7,768 results match your criteria Epistaxis


Factor X deficiency due to a compound heterozygosis between a new mutation (Gla72Asp) in exon 2 and an already known one (Gly154Arg) in exon 5: Factor X Mar del Plata 1).

Cardiovasc Hematol Disord Drug Targets 2018 Dec 11. Epub 2018 Dec 11.

Laboratorio de Hematologia, Sanatorio Allende y Departamento de Bioquimica Clinica, Facultad de Ciencias Quimicas, Universidad Nacional de Cordoba, Cordoba. Argentina.

A compound heterozygote due to the association of a new mutation (Gla72Asp) with an already known mutation (Gly154Arg) of the FX gene is reported. The proposita is a 38 year old female who had a moderate bleeding tendency (menorrhagia, epistaxis, easy bruising). The proposita has never received substitution therapy but in the occasion of a uterine biopsy. Read More

View Article
December 2018

Refractory Severe Thrombocytopenia during Pregnancy: How to Manage.

Rev Bras Ginecol Obstet 2018 Dec 7;40(12):803-807. Epub 2018 Dec 7.

Department of Anaesthesiology, Centro Hospitalar Lisboa Norte, Lisboa, Portugal.

Thrombocytopenia is the most common hemostatic change in pregnancy, but severe thrombocytopenia is rare. One of the causes, immune thrombocytopenic purpura (ITP), is characterized by increased platelet destruction by immunoglobulin G (IgG) antibodies, presenting a high risk of hemorrhage for the patient, but also for the fetus, since antibodies may cross the placenta. We present the case of a 23-year-old pregnant woman with a history of Langerhans cell histiocytosis of the mandible submitted to surgery and chemotherapy when she was 10 years old, with diagnosis of ITP since then. Read More

View Article
December 2018

Prospective, randomized, controlled, open-label study to compare efficacy of a mineral-rich solution vs normal saline after complete ethmoidectomy.

Eur Arch Otorhinolaryngol 2018 Dec 8. Epub 2018 Dec 8.

CHU Bordeaux, CIC 14-01 IT, 33000, Bordeaux, France.

Purposes: The purpose of this study was to compare the efficacy of a mineral-rich solution vs normal saline solution (0.9% NaCl) following endoscopic complete bilateral ethmoidectomy.

Methods: This was a prospective, multicenter, randomized, controlled, open-label trial in subjects suffering from steroid-resistant sinonasal polyposis. Read More

View Article
December 2018

The application of nasoseptal "rescue" flap technique in endoscopic transsphenoidal pituitary adenoma resection.

Neurosurg Rev 2018 Dec 11. Epub 2018 Dec 11.

Department of Neurosurgery, Qilu Hospital, Shandong University, 107 Wenhua Western Rd., Jinan, 250012, Shandong, China.

To explore the reliability and superiority of nasoseptal "rescue" flap technique in neuroendoscopic transnasal pituitary adenoma resection. Retrospective clinical analysis of 113 cases of endoscopic transsphenoid pituitary adenoma resection with the application of nasoseptal "rescue" flap technology. The reliability and the superiority of the technique were evaluated according to the duration of nasal cavity and sphenoid sinus stage, the incidence of postoperative anosmia, and cerebrospinal rhinorrhea. Read More

View Article
December 2018

Platelet transfusion practices in immune thrombocytopenia related hospitalizations.

Transfusion 2018 Dec 5. Epub 2018 Dec 5.

Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Division of Hematology/Oncology, Emory University School of Medicine, Atlanta, Georgia.

Background: The role of platelet transfusions in management of Immune Thrombocytopenia (ITP) remains controversial. Current guidelines recommend that platelet transfusions in ITP be reserved for catastrophic hemorrhage or invasive surgical procedures. This study assesses the nationwide platelet transfusion practices in hospitalized children and adults with ITP. Read More

View Article
December 2018
3 Reads

Giving epistaxis two fingers.

Clin Otolaryngol 2018 Dec 1. Epub 2018 Dec 1.

Royal Berkshire Hospital NHS Foundation Trust, London Road, Reading, RG1 5AN.

Epistaxis is a common presentation to ENT and the use of ice packs is a generally accepted first aid measure. Traditional ice packs on the forehead, bridge of the nose or back of neck can be cumbersome and often requires someone holding onto the ice pack. We describe a simple method to create an ice pack that sits neatly on the nose. Read More

View Article
December 2018
2 Reads

Medical management of haemorrhagic hereditary telangiectasia in adult patients.

Med Clin (Barc) 2018 Nov 27. Epub 2018 Nov 27.

Unidad de Telangiectasia Hemorrágica Hereditaria, Hospital Universitari de Bellvitge-IDIBELL, L'Hospitalet de LLobregat, Barcelona, España; Facultad de Medicina y Ciencias de la Salud, Universitat de Barcelona, Barcelona, España; Unidad de Hepatología y Trasplante hepático, Servicio de Aparato Digestivo, Hospital Universitari de Bellvitge-IDIBELL, L'Hospitalet de LLobregat, Barcelona, España.

Hereditary haemorrhagic telangiectasia (HHT) is an autosomal dominant inherited Rare Disease that causes a systemic anomalous vascular overgrowth. The approach and follow-up of these patients should be from multidisciplinary units. Its diagnosis is carried out according to Curaçao clinical Criteria. Read More

View Article
November 2018
1 Read

Transsphenoidal surgery for pituitary adenomas: early results from a single center.

Hormones (Athens) 2018 Dec 4. Epub 2018 Dec 4.

Endocrinology, Department of Translational Medicine, Università del Piemonte Orientale, Via Solaroli 17, 28100, Novara, Italy.

Objective: To evaluate early results of transsphenoidal surgery for pituitary adenomas.

Design: Retrospective evaluation of 90 consecutive patients undergoing endoscopic pituitary adenoma surgery (2007-2016) at "Maggiore della Carità" Hospital in Novara, Italy. Age at diagnosis, sex, symptoms at presentation, hormonal and radiological data, complications of surgery, and short-term follow-up information were collected. Read More

View Article
December 2018
1 Read

Safety and Tolerability of Pharyngeal High-Resolution Manometry.

Am J Speech Lang Pathol 2018 Dec 4:1-10. Epub 2018 Dec 4.

Department of Surgery, University of Wisconsin-Madison.

Purpose: Pharyngeal high-resolution manometry is an emerging practice for diagnosis of swallowing disorders in the upper aerodigestive tract. Advancement of a catheter through the upper esophageal sphincter may introduce safety considerations. There are no published studies of catheter placement complications, side effects, or tolerability. Read More

View Article
December 2018
3 Reads

A rare presentation of a paediatric sinonasal inverted papilloma.

J Surg Case Rep 2018 Nov 30;2018(11):rjy321. Epub 2018 Nov 30.

Department of Otorhinolaryngology-Head and Neck Surgery, University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, UK.

Sinonasal inverted papilloma (IP) is a benign tumour with an extremely low incidence in children. We report the case of an 11-year-old Caucasian male presenting with recurrent right-sided epistaxis, nasal obstruction and a mass in the right nasal cavity. An initial diagnosis of a nasopharyngeal angiofibroma was considered; however, on detailed histological examination, the mass was found to be an inverted papilloma. Read More

View Article
November 2018

Depression and anxiety levels in mothers of children with epistaxis: A controlled study.

Acta Otorrinolaringol Esp 2018 Nov 30. Epub 2018 Nov 30.

Department of Otorhinolaryngology, Gaziantep 25 Aralık State Hospital, Gaziantep, Turkey.

Introduction: Pediatric epistaxis is very common. A child's illness can lead to depression and anxiety in the parents. The association between pediatric epistaxis and mothers' anxiety has not been well documented. Read More

View Article
November 2018
2 Reads

Comparative Study between Conventional Method and Endonasal Endoscopic Resection of Juvenile Nasopharyngeal Angiofibroma.

Mymensingh Med J 2018 Oct;27(4):785-792

Dr KM Reza-Ul-Haq, Assistant Professor, Department of ENT and Head Neck Surgery, Delta Medical College, Mirpur, Dhaka, Bangladesh.

Juvenile Nasopharyngeal Angiofibroma (JNA) is an uncommon, benign and extremely vascular tumour which accounts for 0.05-0.5% of all head and neck tumours. Read More

View Article
October 2018

Intraoral Endoscopic Ligation of Maxillary Artery in the Infratemporal Fossa.

J Craniofac Surg 2018 Nov 22. Epub 2018 Nov 22.

Department of Otolaryngology - Head and Neck Surgery, Endoscopic Sinus Surgery and Skull Base Surgery, Autonomous University of Veracruz, Xalapa, Mexico.

Ligation of the sphenopalatine and posterior nasal arteries is indicated for posterior epistaxis as initial treatment or when conservative measures fail. In some patients, a transnasal approach or its alternative transantral approach are not possible due to tumor filling the nasal corridor, pterygopalatine fossa, or maxillary sinus. Aim of this study was to evaluate feasibility of endoscopically assisted transoral approach for the ligation of the maxillary artery (MA). Read More

View Article
November 2018
3 Reads

NAVIGATE I: Randomized, Placebo-Controlled, Double-Blind Trial of the Exhalation Delivery System With Fluticasone for Chronic Rhinosinusitis With Nasal Polyps.

Am J Rhinol Allergy 2018 Nov 27:1945892418810281. Epub 2018 Nov 27.

5 OptiNose AS, Oslo, Norway.

Background: Chronic rhinosinusitis is a common, high-morbidity chronic inflammatory disease, and patients often experience suboptimal outcomes with current medical treatment. The exhalation delivery system with fluticasone (EDS-FLU) may improve care by increasing superior/posterior intranasal corticosteroid deposition.

Objective: To evaluate the efficacy and safety of EDS-FLU versus EDS-placebo in patients with nasal polyps (NP). Read More

View Article
November 2018

Massive aneurysmal bone cyst of the skull base treated with denosumab.

Head Neck 2018 Nov 26. Epub 2018 Nov 26.

Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Background: Aneurysmal bone cysts are rare, benign expansile tumors most commonly involving long bones and vertebrae in patients younger than age 20. Skull base involvement is rare. Aneurysmal bone cysts shares radiological and histological features with other bone tumors, posing a diagnostic challenge. Read More

View Article
November 2018
7 Reads

Clinical characteristics of internal carotid artery pseudoaneurysms in the sphenoid sinus.

Am J Otolaryngol 2019 Jan - Feb;40(1):106-109. Epub 2018 Sep 19.

Department of Otorhinolaryngology Head & Neck surgery, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, PR China. Electronic address:

Background: Internal carotid artery (ICA) pseudoaneurysms are associated with high mortality if lack of proper management. Patients with ICA pseudoaneurysms in the sphenoid sinus often visit a hospital's ear, nose and throat (ENT) department due to nasal bleeding. In such cases, simple examination and therapy will lead to misdiagnosis. Read More

View Article
September 2018
5 Reads

Effects of oral isotretinoin therapy on the nasal cavities.

Braz J Otorhinolaryngol 2018 Nov 12. Epub 2018 Nov 12.

Gulhane Medical School, Department of Otolaryngology, Head and Neck Surgery, Ankara, Turkey.

Introduction: Isotretinoin (13 cis-retinoic acid) is the most effective treatment for acne vulgaris and is the only treatment option that can provide either remission or a permanent cure.

Objective: The aim of this study was to use both subjective and objective methods to assess the nasal complaints of patients with severe acne who received oral isotretinoin therapy.

Methods: Fifty-four subjects were enrolled in the study. Read More

View Article
November 2018
1 Read

Documentation and incidence of late effects and screening recommendations for adolescent and young adult head and neck cancer survivors treated with radiotherapy.

Support Care Cancer 2018 Nov 22. Epub 2018 Nov 22.

British Columbia Cancer, Vancouver, BC, Canada.

Purpose: A retrospective review of adolescent and young adult (AYA) head and neck cancer (HNC) patients treated with radiation therapy (RT) at British Columbia Cancer  was performed to determine the incidence of late toxicities, the documented late side effects discussed and the screening recommendations provided at the time of transfer of care to primary care providers (PCPs).

Methods: Charts (n = 162) were reviewed for all patients 15 to 35 years at diagnosis with HNC treated with RT from 1960 to 2010 who survived > 5 years after diagnosis.

Results: A discussion regarding the risk of long-term side effects was documented in the initial consultation for 85% of patients. Read More

View Article
November 2018
4 Reads

Safety of flexible endoscopic evaluation of swallowing examination in gastroenterological practice.

Turk J Gastroenterol 2018 Nov 19. Epub 2018 Nov 19.

Institute for Digestive Research, Digestive Disease Center, Soonchunhyang University Seoul Hospital, Seoul, Republic of Korea.

Background/aims: In South Korea, the flexible endoscopic evaluation of swallowing (FEES) has been increasingly performed by gastroenterologists. The principal concern was the safety of the FEES performed by gastroenterologists without any involvement of speech-language pathologists. We aimed to characterize the safety and tolerance of gastroenterologist-directed FEES examinations (GDFEES). Read More

View Article
November 2018
6 Reads

Epistaxis and mortality.

Authors:

J Laryngol Otol 2018 Nov 20:1-6. Epub 2018 Nov 20.

Background: Epistaxis is a common emergency presentation to ENT. The 'Epistaxis 2016: national audit of management' collected prospective data over a 30-day audit window in 113 centres. A 30-day all-cause mortality rate of 3. Read More

View Article
November 2018
3 Reads

Pediatric Endoscopic Endonasal Approaches for Skull Base Lesions in the Very Young: Is It Safe and Effective?

J Neurol Surg B Skull Base 2018 Dec 30;79(6):574-579. Epub 2018 Apr 30.

Department of Neurosurgery, University of California San Diego, San Diego, California, United States.

 The fully endoscopic expanded endonasal approach (EEA) has been shown to be safe and efficacious in pediatric patients. However, in the very young patient (ages six and under), the anatomical challenge of working through a small nasal corridor is problematic. The ability to repair the skull base and use a nasoseptal flap (NSF) has also been called into question. Read More

View Article
December 2018

Large cell neuroendocrine carcinoma of the nasal cavity: an extremely rare and new distinct entity.

Pan Afr Med J 2018 29;30:188. Epub 2018 Jun 29.

ENT Department, Ibn Sina University Hospital, Mohammed V University, Rabat, Morocco.

Large cell neuroendocrine carcinoma (LCNEC) is a rare but distinct entity of nasal cavity carcinomas. Only a very few cases have been reported in the nasal cavity. Its treatment is not well established. Read More

View Article
December 2018
3 Reads

Epistaxis.

Emerg Med Clin North Am 2019 Feb;37(1):29-39

Division of Emergency Medicine, University of Utah, 30 North 1900 East, Room 1C26, Salt Lake City, UT 84132, USA.

Most anterior epistaxis originates primarily from the Kiesselbach plexus, whereas posterior epistaxis is less common and originates from branches of the sphenopalatine artery. Risk factors include local trauma, foreign body insertion, substance abuse, neoplasms, inherited bleeding diatheses, or acquired coagulopathies. Assessment of airway, breathing, and circulation precedes identification of bleeding source, pain control, and achieving hemostasis. Read More

View Article
February 2019
4 Reads

NUT carcinoma of the nasal cavity that responded to a chemotherapy regimen for Ewing's sarcoma family of tumors: a case report.

BMC Cancer 2018 Nov 19;18(1):1134. Epub 2018 Nov 19.

Department of Hematology/Oncology, Japan Community Healthcare Organization Kyushu Hospital, Fukuoka, Japan.

Background: Nuclear protein in testis (NUT) carcinoma (NC) is a rare epithelial malignancy characterized by rearrangement of the NUT gene on chromosome 15. If NC is not suspected, it is often diagnosed as other malignancies. We present the case of NC of the nasal cavity that responded to a chemotherapy regimen for Ewing's sarcoma family of tumors (ESFT). Read More

View Article
November 2018
7 Reads

Mirtazapine-Induced Epistaxis in an Australian Indigenous Man.

Prim Care Companion CNS Disord 2018 Oct 25;20(5). Epub 2018 Oct 25.

View Article
October 2018

Choanal polyps in children and adults: 10-year experience from a tertiary care hospital.

Eur Arch Otorhinolaryngol 2018 Nov 14. Epub 2018 Nov 14.

Institute for Pathology, Military Medical Academy Faculty of Medicine, Belgrade, Serbia.

Purpose: Choanal polyps (CPs) are benign, solitary, soft-tissue lesions extending towards the junction between the nasal cavity and the nasopharynx through the choana. The aim of this retrospective study was to evaluate clinical and histological characteristics of CPs in children comparing to adult patients.

Methods: Characteristics of CPs treated in our hospital (demography, main complaints, side, localization, surgical approach, histological characteristics, accompanying paranasal sinus diseases, association with allergic rhinitis, postoperative follow-up period, and recurrence rates) were retrospectively reviewed. Read More

View Article
November 2018
2 Reads

Analysis of Patients with Ventricular Assist Devices Presenting to an Urban Emergency Department.

West J Emerg Med 2018 Nov 10;19(6):907-911. Epub 2018 Sep 10.

Harvard University, Massachusetts General Hospital, Department of Emergency Medicine, Boston, Massachusetts.

Introduction: Left ventricular assist device (LVAD) insertion is an increasingly common intervention for patients with advanced heart failure; however, published literature on the emergency department (ED) presentation of this population is limited. The objective of this study was to characterize ED presentations of patients with LVADs with a focus on device-specific complications to inform provider education and preparation initiatives.

Methods: This was a retrospective chart review of all patients with LVADs followed at an urban academic medical center presenting to the ED over a five-year period (July 1, 2009, to June 30, 2014). Read More

View Article
November 2018
4 Reads

Treatment of Refractory Adrenocortical Carcinoma with Thalidomide: Analysis of 27 Patients from the European Network for the Study of Adrenal Tumours Registry.

Exp Clin Endocrinol Diabetes 2018 Nov 14. Epub 2018 Nov 14.

Department of Internal Medicine I, Endocrine and Diabetes Unit, University Hospital Würzburg, University of Würzburg, Germany.

Objective: Adrenocortical carcinoma (ACC) is a rare malignancy with a dismal prognosis. In advanced stages, tumour control by mitotane and cytotoxic chemotherapy is often temporary and salvage treatments are warranted.

Methods: Retrospective cohort study of participants in the prospective European Networks for the Study of Adrenal Tumours (ENSAT) registry. Read More

View Article
November 2018
8 Reads

Chronic sinusitis-associated antrolith.

IDCases 2018 3;14:e00467. Epub 2018 Nov 3.

VA NY Harbor Healthcare System, Brooklyn Campus, 800 Poly Place, Brooklyn, NY 11209, USA.

An antrolith is a calcified mass found in the nasal cavity or sinus, usually maxillary, described in literature as a rare phenomenon. Its presenting symptoms are variable and include symptoms associated with chronic sinusitis. We describe a 66 year old man with chronic sinusitis who presented with facial pain and epistaxis and upon further evaluation was found to have an antrolith of the left maxillary sinus. Read More

View Article
November 2018
1 Read

A comparative study of gloved versus ungloved merocel as nasal pack after septoplasty.

Niger J Clin Pract 2018 Nov;21(11):1391-1395

CHC, Patiala, Punjab, India.

Introduction: Septoplasty or septal reconstruction is a corrective surgical procedure performed to straighten the nasal septum. It may be associated with numerous complications. To minimize these complications, both nasal cavities are frequently packed with different types of nasal packing. Read More

View Article
November 2018
7 Reads

Early discharge of pediatric patients with cancer, fever, and neutropenia with low-risk of systemic infection.

Bol Med Hosp Infant Mex 2018 ;75(6):352-357

Unidad de Investigación en Análisis y Síntesis de la Evidencia, Centro Médico Nacional Siglo XXI, IMSS, Coordinación de Investigación, Instituto Mexicano del Seguro Social, Mexico City.

Background: Ambulatory therapy in low-risk patients with cancer, fever, and neutropenia seems to be a secure and effective alternative. This study aimed to compare the effectiveness and safety of the antimicrobial treatment in early discharge vs. in-hospital treatment in children with cancer and febrile neutropenia (FN) with low risk of invasive bacterial infection (IBI). Read More

View Article
January 2018
2 Reads

Stop the bleed campaign: A qualitative study from our experience from the middle east.

Ann Med Surg (Lond) 2018 Dec 24;36:67-70. Epub 2018 Oct 24.

Mubarak Al-Kabeer Hospital, Kuwait.

Background: Bleeding due to unintentional injuries are a leading cause of death in the younger population. The immediate involvement of lay bystanders has been proven to be imperative in outcomes, however, there still is less than 30% of out-of-hospital resuscitation attempts initiated by them.

Study Design: The Stop the Bleed campaign was initiated in Kuwait in September-2017, with the aim to raise awareness and train the general public on emergency situations. Read More

View Article
December 2018
7 Reads

Hemorrhage within the tympanic membrane without perforation.

J Otolaryngol Head Neck Surg 2018 Nov 6;47(1):66. Epub 2018 Nov 6.

Department of Otorhinolaryngology-Head and Neck Surgery, Konkuk University School of Medicine, Konkuk University Medical Center, 120-1 Neungdong-ro (Hwayang-dong), Gwangjin-gu, Seoul, 143-729, Republic of Korea.

Background: Hemotympanum refers to both the presence of blood in the middle ear cavity and to ecchymosis of the tympanic membrane (TM), and a systematic study of intra-TM (iTM) hemorrhage without bleeding in the middle ear cavity has not been conducted. The goals of our study were to analyze the causes of iTM hemorrhage without TM perforation or bleeding in the middle ear cavity, and to demonstrate the clinical characteristics of the disease.

Methods: This Case series study included five patients with iTM hemorrhage between August 2014 and August 2017. Read More

View Article
November 2018
5 Reads

Efficacy and Safety of Daflon® in the Treatment of Idiopathic Epistaxis.

Authors:
Tamer M Attia

Am J Rhinol Allergy 2018 Nov 5:1945892418809237. Epub 2018 Nov 5.

1 Department of Otolaryngology, Faculty of Medicine, Menoufia University, Al Minufya, Egypt.

Background: Epistaxis is a very common ENT emergency with the idiopathic variety being the commonest type. Daflon® is a mixture of flavonoids with beneficial vascular effects that may help in the treatment of epistaxis.

Objective: To assess the efficacy and safety of Daflon® in the treatment of idiopathic epistaxis. Read More

View Article
November 2018
5 Reads

12q13.12q13.13 microdeletion encompassing ACVRL1 and SCN8A genes: Clinical report of a new contiguous gene syndrome.

Eur J Med Genet 2018 Oct 30. Epub 2018 Oct 30.

Hospices Civils de Lyon, Genetic Department and National HHT Reference Center, Femme-Mère-Enfants Hospital, Bron, F-69677, France.

Hereditary hemorrhagic telangiectasia is usually linked to the presence of a pathogenic mutation ACVRL1 or ENG. Thus, apparently there is no benefit to perform an array CGH in case of HHT. However, ENG has been involved in a contiguous gene syndrome due to a de novo 9q33. Read More

View Article
October 2018
6 Reads

Renal cell carcinoma presenting as epistaxis from a nasal cavity metastasis.

Radiol Case Rep 2019 Jan 26;14(1):116-120. Epub 2018 Oct 26.

University of Illinois at Chicago, 1740 West Taylor Street, Chicago, IL 60612, USA.

We present a 58-year-old gentleman who initially presented to the otolaryngology clinic with new onset epistaxis revealing a palpable facial mass that was subsequently biopsied revealing metastatic renal cell carcinoma. We hope to present an interesting case highlighting the rarity of this disease and unusual presentation in which the presence of the primary renal cell carcinoma was recognized only after biopsy. Read More

View Article
January 2019
2 Reads

An unusual complication of posterior packing in epistaxis.

North Clin Istanb 2018 12;5(2):157-159. Epub 2018 Apr 12.

Department of Emergency Medicine, Adıyaman University Training and Research Hospital, Adıyaman, Turkey.

Endonasal or transnasal procedures are sometimes necessary in patients with head trauma. Before these procedures, the integrity of the skull base must be considered to avoid penetration of the cranial vault. A 54-year-old man was taken to a district hospital following a car accident. Read More

View Article
April 2018
4 Reads

[A Case of Pseudoaneurysm of the Lingual Artery that was Difficult to be Distinguished from Epistaxis].

No Shinkei Geka 2018 Oct;46(10):911-916

Department of Endovascular Surgery, Tokyo Medical and Dental University.

We describe the case of a 75-year-old man with pharyngeal hemorrhage caused by a pseudoaneurysm of the lingual artery after accidentally swallowing his dentures. He developed sudden oral and nasal hemorrhage and was transported to a hospital near his residence. The doctors at the hospital diagnosed the case as epistaxis and treated the symptom with nasal packing. Read More

View Article
October 2018
5 Reads

Ethnopharmacological study of Sephardic remedies in the 19th century: The "Livro de Milizinas".

J Ethnopharmacol 2019 Feb 21;230:20-73. Epub 2018 Oct 21.

Dpto. Ecología e Hidrología, Campus de Espinardo, Universidad de Murcia, 30100 Murcia, Spain. Electronic address:

Ethnopharmacological Relevance: The Sephardic or Judeo-Spanish communities kept a cultural heritage extremely relevant which is recognizable through the peculiar form of their language and practices. Medicine was one of the main professional activities among Jews of Spain before their expulsion in 1492. We expected to find ingredients and recipes in the Sephardic traditional medicine related to classical medicine and to modern ethnopharmacology of Spain, but also influenced by the host countries. Read More

View Article
February 2019
7 Reads

Weak correlation of bleeding scores to platelet electron microscopy: A retrospective chart review of pediatric patients with delta-storage pool disorder.

Pediatr Blood Cancer 2018 Oct 21:e27505. Epub 2018 Oct 21.

Department of Pediatric Hematology Oncology, University of California-Davis, Davis, California.

Background: Delta granule storage pool deficiency (δ-SPD) is a rare platelet disorder in which a deficiency of platelet granules leads to poor aggregation, resulting in varying clinical bleeding phenotypes. Children with δ-SPD have variable laboratory results, making the proper diagnosis and evaluation controversial.

Objectives: To describe the demographic and laboratory trends of this population and to assess the value of electron microscopy in diagnostic evaluation and its correlation to bleeding symptoms. Read More

View Article
October 2018
4 Reads

Acute Brucellosis Presenting with Bleeding Tendency due to Isolated Severe Thrombocytopenia.

Authors:
M Aon T Al-Enezi

Case Rep Infect Dis 2018 23;2018:7867435. Epub 2018 Sep 23.

Department of Medicine, Jahra Hospital, Al-Jahra, Kuwait.

Mild anemia and leukopenia are the most common hematologic findings in the course of acute brucellosis. Severe form of thrombocytopenia is less frequently reported. We describe a case of acute brucellosis in a 20-year-old man, who presented with fever, purpuric skin lesions, epistaxis, and hematuria. Read More

View Article
September 2018
2 Reads

Clinical features and outcome in paediatric newly diagnosed immune thrombocytopenic purpura in a tertiary care centre.

Pak J Med Sci 2018 Sep-Oct;34(5):1195-1199

Shazia Riaz, MD. Department of Paediatric Haematology, Oncology and Bone Marrow Transplant, The Children's Hospital and the Institute of Child Health, Lahore, Pakistan.

Objective: The study aimed to demonstrate the pattern of clinical presentations and outcome of acute Immune Thrombocytopenia (ITP) in our Centre.

Methods: A descriptive, observational study was conducted by collecting and analysing the data of 103 patients of acute ITP, ageing between 1-14 years, at The Children's Hospital, Lahore from January 2016 to December 2016. We collected the data regarding age, sex, clinical presentations, history of preceding viral infections, vaccination history, laboratory values, different treatment options used, and response to the treatment concerning complete response, partial response and poor responders. Read More

View Article
October 2018
6 Reads

Topical use of tranexamic acid for the management of post-procedural rectal bleeding.

Am J Emerg Med 2019 Jan 25;37(1):173.e3-173.e4. Epub 2018 Sep 25.

Department of Emergency Medicine, Boston Medical Center, 1 Boston Medical Center Place, Boston 02118, MA, USA.

Tranexamic acid (TXA) is increasingly used in the Emergency Department (ED). While the intravenous form has been extensively studied and used, it's utility in a topical formulation is not as widespread. Its reported use in the ED is mostly for control of epistaxis. Read More

View Article
January 2019

Sinuses and Common Rhinologic Conditions.

Med Clin North Am 2018 Nov 18;102(6):993-1000. Epub 2018 Aug 18.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, 601 North Caroline Street, 6th Floor, Baltimore, MD 21287, USA. Electronic address:

Some of the most common rhinologic disorders that may present to the primary care provider include disorders of hemostasis, such as epistaxis, or sinonasal inflammatory disorders, such as allergic rhinitis and acute or chronic rhinosinusitis. This article is written with the intent to review these common rhinologic conditions for primary care providers and to summarize symptoms, diagnostic testing, differential diagnosis, and management/treatment approaches. Read More

View Article
November 2018
5 Reads

Endoscopic management of Esthesioneuroblastoma: Our experience and review of the literature.

J Clin Neurosci 2018 Dec 16;58:117-123. Epub 2018 Oct 16.

Division of Neurosurgery, Toronto Western Hospital, University Health Network, Toronto, ON, Canada.

During the last two decades evolution of the endoscopic endonasal approaches (EEA) has offered the option of minimally invasive techniques in the management of esthesioneuroblastomas (ENB), either as endoscope assisted cranial resection or as pure endoscopic procedures. This study presents the use of pure EEA in the management of ENB in our center, along with a literature review. We retrospectively reviewed the clinical, radiology and pathology records of patients with ENB treated during the period July 2006 to January 2016. Read More

View Article
December 2018
4 Reads

Arterial Blood Supply of the Nose: An Angiographic Study.

ORL J Otorhinolaryngol Relat Spec 2018 Oct 18:1-10. Epub 2018 Oct 18.

Otorhinolaryngology, Ain Shams University Faculty of Medicine, Cairo, Egypt.

Objective: To define anatomical variations associated with arterial blood supply of the nose which has clinical implications on the management of different disorders, especially intractable posterior epistaxis.

Study Design: Case series.

Methods: Selective angiography of external and internal carotid arteries of 100 patients scheduled for routine angiography was done. Read More

View Article
October 2018
1 Read
0.670 Impact Factor

Pentraxin 3 level is elevated in hereditary hemorrhagic telangiectasia and reflects the severity of disease-associated epistaxis.

Laryngoscope 2018 Oct 17. Epub 2018 Oct 17.

Department of Otorhinolaryngology-Head and Neck Surgery, Division of Head and Neck and Reconstructive Surgery, Oslo University Hospital, Rikshospitalet, Oslo, Norway.

Objectives/hypothesis: We aimed to investigate if vascular endothelial growth factor (VEGF) and other angiogenic and inflammatory factors correlated with the clinical presentation in hereditary hemorrhagic telangiectasia (HHT) patients, particularly in regard to the severity of epistaxis.

Study Design: Prospective, comparative, single-center study.

Methods: One hundred nine samples were collected from 75 HHT patients attending the ear, nose, and throat department at Oslo University Hospital from February 2012 to August 2013. Read More

View Article
October 2018

Giant petrous internal carotid aneurysm causing epistaxis: A case report.

J Clin Neurosci 2018 Dec 13;58:221-223. Epub 2018 Oct 13.

Department of Neurosurgery, Sapporo Medical University, Sapporo, Japan.

Aneurysms of the internal carotid artery (ICA) arising from the petrous portion are extremely rare, and most cases are asymptomatic or cause a mass effect leading to palsy of the adjacent cranial nerves. In rupture cases, massive nasal and ear bleeding occurs, which may cause death. We describe a 73-year-old man with a giant ICA aneurysm arising from the petrous portion and presenting as epistaxis. Read More

View Article
December 2018
3 Reads

Epistaxis in the setting of antithrombotic therapy: A comparison between factor Xa inhibitors, warfarin, and antiplatelet agents.

Laryngoscope 2018 Oct 16. Epub 2018 Oct 16.

Department of Otolaryngology-Head and Neck Surgery, Sheba Medical Center, Tel-Hashomer, Israel.

Objectives/hypothesis: To describe the characteristics and severity of epistaxis in patients taking factor Xa inhibitors novel anticoagulants.

Study Design: Retrospective cohort study.

Methods: A study of adult patients hospitalized due to spontaneous epistaxis under the treatment of warfarin, rivaroxaban, or apixaban between the years 2011 and 2017 was performed. Read More

View Article
October 2018
1 Read

Intranasal Lobular Capillary Hemangioma with Multiple Sites of Origin during Pregnancy: A Case Report and Literature Review.

Case Rep Otolaryngol 2018 18;2018:7413918. Epub 2018 Sep 18.

Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, Saudi Arabia.

In the present case report, we describe a 33-year-old pregnant woman in the third trimester with a history of recurrent epistaxis leading to frequent visits to the emergency department. Each episode of epistaxis was managed by anterior nasal packing. During endoscopic examination, a left nasal mass was seen. Read More

View Article
September 2018
1 Read