Epilepsy Res 2022 May 25;182:106913. Epub 2022 Mar 25.
Division of Neurosurgery, The Hospital for Sick Children, 555 University Ave., Toronto, Ontario, Canada; Department of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada; Program in Neuroscience and Mental Health, Hospital for Sick Children, Toronto, Ontario, Canada. Electronic address:
The thalamus is a densely connected collection of nuclei that play a critical role in gating information flow across the neocortex. Through diffuse reciprocal cortico-thalamo-cortical connectivity, the anterior and centromedian nuclei exert remarkable control over cortically expressed activity. Consequently, mounting evidence implicates these thalamic centres in both the genesis and propagation of aberrant epileptiform activity across the brain. Read More