3,382 results match your criteria Epididymitis


Isolation of and from a 2-month-old calf with chronic fibrosing and suppurative epididymitis.

Can Vet J 2020 Jul;61(7):776-778

Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1.

A 2-month-old red Angus crossbred calf was evaluated for a severely swollen scrotum, approximately 30 cm in diameter. Culture of the lesion isolated both and A final diagnosis based on the histopathology report was chronic fibrosing epididymitis with testicular atrophy and mild orchitis. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313357PMC

Increase of leucocyte-derived extracellular traps (ETs) in semen samples from human acute epididymitis patients-a pilot study.

J Assist Reprod Genet 2020 Jul 10. Epub 2020 Jul 10.

Institute of Parasitology, Justus Liebig University Giessen, Giessen, Germany.

Purpose: To study the effector mechanism against pathogens of polymorphonuclear neutrophils (PMN) and macrophages, called ETosis, involving the release of extracellular traps (ETs) in patients with acute epididymitis. To assess the different ET phenotypes present in semen samples and to identify correlations between ETosis and clinical parameters.

Materials And Methods: Samples from patients diagnosed with acute epididymitis were examined and compared with samples from uninfected controls. Read More

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http://dx.doi.org/10.1007/s10815-020-01883-7DOI Listing

[Complications of the acute scrotum syndrome in children].

Urologiia 2020 Jun(3):77-80

FGBOU VO Yaroslavl state medical university of the Ministry of Health of the Russian Federation, Yaroslavl, Russia.

Aim: To establish causes of complications and repeated surgical procedures in patients with acute scrotal pathology during the short- and long-term follow-up.

Materials And Methods: The treatment results of 3315 patients aged 0 to 18 years with various forms of acute scrotal pathology were analyzed.

Results: A total of 43 complications were documented, 32 of them required surgical intervention. Read More

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How common are traumatic injuries to the epididymis? A study of prevalence, imaging appearance, and management implications.

Emerg Radiol 2020 Jun 27. Epub 2020 Jun 27.

Department of Radiology and Biomedical Imaging, University of California San Francisco and Zuckerberg San Francisco General Hospital, 1001 Potrero Ave. Building 5, 1X57, San Francisco, CA, 94110, USA.

Purpose: To evaluate the prevalence of epididymal injuries with scrotal trauma, review imaging appearance, clinical management, and outcomes.

Methods: In this retrospective study, the radiology report database was queried for scrotal ultrasounds containing keywords pertaining to trauma, from 1998 to 2019. Exams with no clinically documented trauma, exams with trauma > 1 year ago, and duplicate exams were excluded. Read More

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http://dx.doi.org/10.1007/s10140-020-01814-0DOI Listing

Cystoscopy-Guided Laparoscopic Excision of Prostatic Utricle: Report of a Case.

European J Pediatr Surg Rep 2020 Jan 28;8(1):e35-e38. Epub 2020 Apr 28.

Department of Pediatric Surgery, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Prostatic utricle (PU) is incomplete regression of Müllerian duct and may cause recurrent urinary tract infections (UTIs), stone formation, postvoid dribbling, and recurrent epididymitis. Although surgical excision is recommended to avoid complications, surgical access to PU has been challenging. Cystoscopy-guided laparoscopic management of PU in a 3-year-old boy is reported to discuss use of other endoscopic aids in the surgical treatment of PU. Read More

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http://dx.doi.org/10.1055/s-0040-1705155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188514PMC
January 2020

What is beyond testicular torsion and epididymitis? Rare differential diagnoses of acute scrotal pain in adults: A systematic review.

Ann Med Surg (Lond) 2020 Jul 29;55:265-274. Epub 2020 May 29.

Department of Urology, University Hospital Leipzig, Germany.

Background: Acute scrotal pain is a urological emergency. While for testicular torsion and acute epididymitis clinical recommendations are well established, few is known about low incidence causes of acute scrotal pain. Our aim is to identify and characterise rare differential diagnoses of acute scrotal pain in order to give diagnostic and therapeutic recommendations. Read More

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http://dx.doi.org/10.1016/j.amsu.2020.05.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283975PMC

In silico vaccine design against infection.

Netw Model Anal Health Inform Bioinform 2020 10;9(1):39. Epub 2020 Jun 10.

Biodiscovery Group for Life Sciences, Bangalore, India.

a gram-negative bacterium known to infect the genital sites mainly columnar epithelial cells of the cervix, urethra and rectum in women and causes acute epididymitis, urinary tract inflammation and DNA damage to the sperms in men, hence considered to be one of the major sexually transmitted infections. The infection is asymptomatic in many people and remains untreated leading to serious health complications, including pelvic inflammatory disease, ectopic pregnancy and infertility. The current treatment options include antibiotics, but the pathogen has gained resistance against many antibiotics. Read More

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http://dx.doi.org/10.1007/s13721-020-00243-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283423PMC

Polyarteritis nodosa with genital necrosis.

Urol Case Rep 2020 Nov 28;33:101285. Epub 2020 May 28.

Chairman of Urology, Clínica San Camilo, Buenos Aires, Argentina.

Polyarteritis nodosa (PAN) is a multisystemic disease that is characterized by the presence of necrotizing vasculitis of small and medium-sized blood vessels. Genital compromise is rare. Our patient presented a systemic disease associated to genital signs (penis and scrotum skin necrosis). Read More

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http://dx.doi.org/10.1016/j.eucr.2020.101285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270192PMC
November 2020

Testicular torsion in geriatric 82-year old man.

Urol Case Rep 2020 Nov 19;33:101258. Epub 2020 May 19.

Department of Urology, University Hospital Ulm, Albert-Einstein-Allee 23, 89081, Ulm, Germany.

The leading cause of scrotal pain in the geriatric population is epididymitis. Testicular torsion is rare in adult men. This case report of an 82-year old man with acute scrotum represents the second oldest patient reported in published studies. Read More

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http://dx.doi.org/10.1016/j.eucr.2020.101258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267712PMC
November 2020

Challenges in the diagnosis of testicular infarction in the presence of prolonged epididymitis: Three cases report and literature review.

J Xray Sci Technol 2020 May 24. Epub 2020 May 24.

Department of Urology and Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.

Introduction: Testicular infarction is a rare complication of prolonged epididymitis and may be misdiagnosed as testicular torsion. In this study, we present three cases of testicular infarction and discuss their clinical characteristics, imaging features and clinical management.

Patients And Methods: Three adult males with prolonged epididymitis presented with chronic unilateral testicular pain, tenderness, and palpable swelling, including left varicocele in one case and hydrocele in the other two cases. Read More

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http://dx.doi.org/10.3233/XST-200671DOI Listing

Multilocus sequence typing characterizes diversity of Ureaplasma diversum strains, and intra-species variability induces different immune response profiles.

BMC Vet Res 2020 May 26;16(1):163. Epub 2020 May 26.

Universidade Estadual de Santa Cruz, Brazil, Jorge Amado Highway, Km 16, Salobrinho, Ilheus, Bahia, 45662-900, Brazil.

Background: Ureaplasma diversum is a pathogen found in the genital tract of cattle and associated with genital disorders such as infertility, placentitis, abortion, birth of weak calves, low sperm motility, seminal vesiculitis and epididymitis. There are few studies evaluating the genetic diversity of U. diversum strains and their influence on the immune response in cattle. Read More

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http://dx.doi.org/10.1186/s12917-020-02380-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249313PMC

Transcriptome Landscape of Intracellular Brucella ovis Surviving in RAW264.7 Macrophage Immune System.

Inflammation 2020 May 19. Epub 2020 May 19.

College of Animal Science, Southwest University, Chongqing, 402460, People's Republic of China.

Brucella ovis infection results in genital damage and epididymitis in rams, placental inflammation and rare abortion in ewes, and neonatal mortality in lambs. However, the mechanism underlying B. ovis infection remains unclear. Read More

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http://dx.doi.org/10.1007/s10753-020-01239-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235551PMC
May 2020
1.921 Impact Factor

Non-surgical management of methamphetamine induced testicular ischemia.

Urol Case Rep 2020 Sep 3;32:101238. Epub 2020 May 3.

Urologist at Royal Perth Hospital, Victoria Square, Perth, 6000, Australia.

A rare case of methamphetamine induced testicular ischemia, a 35-year-old man with clinical and sonographic features of left epididymitis. However, Ultrasound incidentally showed a lack of vascularity of the right testicle despite being asymptomatic on the right hemi-scrotum. He was a known intravenous methamphetamine user, admitting his last injection was 4 h prior to his presentation. Read More

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http://dx.doi.org/10.1016/j.eucr.2020.101238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217995PMC
September 2020

Tumor of the epididymis: an uncommon presentation of disseminated coccidioidomycosis.

Rev Inst Med Trop Sao Paulo 2020 11;62:e24. Epub 2020 May 11.

Hospital Universitario "Dr. Jose Eleuterio Gonzalez", Facultad de Medicina, Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Leon, Mexico.

Coccidioidomycosis is an endemic disease of arid regions in the Western hemisphere. Its clinical presentation varies from asymptomatic nodules on chest x-rays to disseminated disease. We present the case of a 48-year-old man with a hard and heterogeneous tumor in the posterior aspect of the right testis. Read More

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http://dx.doi.org/10.1590/s1678-9946202062024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232960PMC

Is Non-Chlamydial Non-Gonococcal Urethritis Associated with Significant Clinical Complications in Men? A Systematic Review.

Curr Urol 2020 Mar 20;14(1):1-13. Epub 2020 Mar 20.

East and North Hertfordshire NHS Trust, Department of Urology, Lister Hospital, Stevenage.

Background: It is estimated that between 50 and 89% of non-gonococcal urethritis is not caused by . Associations between non-chlamydial non-gonococcal urethritis (NCNGU) with balanoposthitis, epididymo-orchitis and reactive arthritis have been suggested, but evidence to support these often-theoretical relationships is sparse and further investigation is called for. Concerns over increasing antimicrobial resistance has rendered the need for clarity over this question ever more pressing in recent years. Read More

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http://dx.doi.org/10.1159/000499266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206600PMC

Region-specific immune responses to autoimmune epididymitis in the murine reproductive tract.

Cell Tissue Res 2020 May 8. Epub 2020 May 8.

Centre for Reproductive Health, Hudson Institute of Medical Research, Clayton, Victoria, Australia.

Epididymitis is a common pathology of the male reproductive tract, potentially leading to infertility. Studies on bacterial epididymitis indicate that the cauda epididymis is more susceptible to inflammatory damage than the caput. These regional differences in immunoregulation are further investigated using an experimental autoimmune epididymo-orchitis model. Read More

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http://dx.doi.org/10.1007/s00441-020-03215-8DOI Listing

Typhimurium Triggered Unilateral Epididymo-Orchitis and Splenomegaly in a Holstein Bull in Assiut, Egypt: A Case Report.

Pathogens 2020 Apr 24;9(4). Epub 2020 Apr 24.

Department of Anatomy, Embryology and Histology, Faculty of Veterinary Medicine, Assiut University, 71526 Assiut, Egypt.

This report illustrates, for the first time, a case of unilateral orchitis and epididymitis in a Holstein-Friesian bull, associated with infection ( serovar Typhimurium). A one and a half-year-old Holstein-Friesian bull had arrived at the Veterinary Hospital of Assiut University suffering from anorexia accompanied with persistent fever, which did not respond to oxytetracycline and flunixin meglumine injection for 15 days. Gross examination revealed left scrotal enlargement (three times its normal size), heat sensation, and induration of the testis and epididymis, which was painful on external palpation. Read More

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http://dx.doi.org/10.3390/pathogens9040314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238186PMC

A Teenager With Recurrent Epididymitis.

Urology 2020 Jul 22;141:e10. Epub 2020 Apr 22.

Children's Hospital of Philadelphia, Philadelphia, PA.

A 17-year-old man with a history of imperforate anus presented to clinic with recurrent epididymitis. A fluoroscopic voiding cystourethrogram demonstrated urethra-ejaculatory duct reflux. A narrowing was also noted in the distal prostatic urethra with dilation of the proximal urethra. Read More

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http://dx.doi.org/10.1016/j.urology.2020.04.051DOI Listing

Transurethral resection of ejaculatory duct combined with seminal vesiculoscopy for management of persistent or recurrent hemospermia in men with ejaculatory duct obstruction.

BMC Urol 2020 Mar 23;20(1):34. Epub 2020 Mar 23.

Department of Urology, Institute of Urology, West China Hospital, Sichuan University, 37, Guo Xue Road, Chengdu, 610041, Sichuan Province, China.

Background: Persistent or recurrent haemospermia often occurs in individuals with ejaculatory duct obstruction (EDO). This study aimed to evaluate the efficacy and safety of transurethral resection of the ejaculatory duct (TURED) combined with seminal vesiculoscopy in treating persistent or recurrent haemospermia in men with EDO.

Methods: From June 2014 to March 2018, 103 consecutive patients with EDO who underwent TURED combined with seminal vesiculoscopy for persistent or recurrent haemospermia at the Department of Urology of West China Hospital were enrolled into this retrospective study. Read More

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http://dx.doi.org/10.1186/s12894-020-00589-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087380PMC

The role of multiparametric ultrasound in the diagnosis of paediatric scrotal pathology.

Br J Radiol 2020 Jun 23;93(1110):20200063. Epub 2020 Apr 23.

Department of Radiology, King's College Hospital, London. Denmark Hill, London SE5 9RS U.K, United Kingdom.

Multiparametric ultrasound (MPUS), combining conventional techniques (greyscale and colour Doppler ultrasound), ultrasound strain elastography, and contrast-enhanced ultrasound (CEUS), has been successfully used in the assessment of adult scrotal pathology. Contrast-enhanced ultrasound can confidently establish testicular tissue vascularity even in the small-volume paediatric testis. Elastography provides further assessment of tissue stiffness, potentially adding useful diagnostic information. Read More

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http://dx.doi.org/10.1259/bjr.20200063DOI Listing
June 2020
1.533 Impact Factor

Assessing the Utility of Ultrasound and Urinalysis for Patients with Possible Epididymo-Orchitis - A Retrospective Study.

Open Access Emerg Med 2020 13;12:47-51. Epub 2020 Mar 13.

Department of Emergency Medicine, Kendall Regional Medical Center, Miami, FL, USA.

Purpose: Many experts recommend ordering an ultrasound and a urinalysis on all patients with scrotal pain. While the ultrasound may help diagnose a number of potential causes of scrotal pain, the urinalysis primarily has value in assessing for epididymo-orchitis. This study sought to evaluate the utility of these diagnostic tests for patients who presented to the emergency department (ED) with acute scrotal pain and possible epididymo-orchitis. Read More

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http://dx.doi.org/10.2147/OAEM.S234413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081061PMC

Clinical features of Behcet's disease in Mongolia: a multicenter study.

Clin Rheumatol 2020 Mar 10. Epub 2020 Mar 10.

Department of Ophthalmology, Health Sciences University of Hokkaido Hospital, Ainosato 2-5, Kita-ku, Sapporo, 002-8072, Japan.

Objective: The aim of the present study is to investigate the clinical features of patients with Behcet's disease (BD) in Mongolia.

Methods: Patients were identified and examined from six medical institutions in Mongolia from January 2015 to January 2019. BD was diagnosed according to the diagnostic criteria for BD established by the International Study Group. Read More

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http://dx.doi.org/10.1007/s10067-020-05019-1DOI Listing
March 2020
1.774 Impact Factor

Incidental imaging findings suggesting Zinner syndrome in a young patient with pulmonary embolism: A case report.

Radiol Case Rep 2020 Apr 19;15(4):437-441. Epub 2020 Feb 19.

Central Radiology Institute, Kepler University Hospital, Medical Faculty of the Johannes Kepler University, Krankenhausstrasse 9, Linz, Austria.

A triad of seminal vesical cyst, ipsilateral renal agenesis and ipsilateral ejaculatory duct obstruction is known as Zinner Syndrome. First described in 1914, only about 200 cases have been reported in literature. Usually it stays undiagnosed until the second to third decade of life due to lack of symptoms or nonspecific symptoms such as lower urinary tract symptoms, dysuria or painful ejaculation. Read More

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http://dx.doi.org/10.1016/j.radcr.2020.01.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033301PMC

S100A4 promotes the progression of lipopolysaccharide-induced acute epididymitis in mice†.

Biol Reprod 2020 May;102(6):1213-1224

National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, People's Republic of China.

S100A4 has been suggested to be a critical regulator of tumor metastasis and is implicated in the progression of inflammation. The aim of this study is to investigate the expression and possible role of S100A4 in epididymitis. Using a mouse model of epididymitis induced by the injection of lipopolysaccharide (LPS) in the deferent duct, we found that LPS administration induced an upregulation of S100a4 transcription (P < 0. Read More

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http://dx.doi.org/10.1093/biolre/ioaa022DOI Listing

Complete testicular infarction secondary to epididymoorchitis and pyocele.

Radiol Case Rep 2020 Apr 12;15(4):420-423. Epub 2020 Feb 12.

Donald and Barbara Zucker School of Medicine at Hofstra, Department of Radiology, Northwell at Staten Island University Hospital, 475 Seaview Avenue, Staten Island, NY, USA.

Epididymoorchitis is a relatively common urologic condition involving the scrotum which presents with unilateral pain and swelling. It is typically treated with antibiotics but can progress to complications such as scrotal pyocele. Global testicular infarction is an exceedingly rare but devastating complication of epididymoorchitis. Read More

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http://dx.doi.org/10.1016/j.radcr.2020.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016336PMC

Ectopic Intravesical Ejaculatory Ducts: Case Report of Bulking Agent Injection for Treatment of Recurrent Epididymitis in a Patient With Anorectal Malformation.

Urology 2020 Jun 15;140:162-164. Epub 2020 Feb 15.

Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel; Urology Unit, Schneider Children's Medical Center of Israel, Petah Tikva, Israel.

As far as we know this is the first report on bulking agent injection into intravesical ectopic ejaculatory orifices reported in the English literature. During a follow-up period of 23 months, the child was free of episodes of epididymo-orchitis. Deflux injection in this rare anomaly of intravesical refluxing ducts had prevented irreversible damage to the testes from recurrent EO. Read More

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http://dx.doi.org/10.1016/j.urology.2020.02.003DOI Listing

[Acute idiopathic scrotal edema-an underestimated differential diagnosis of acute scrotum].

Urologe A 2020 Mar;59(3):266-270

Klinik für Kinderurologie in Kooperation mit der Universität Regensburg, KUNO-Klinik St. Hedwig, Steinmetzstraße 1-3, 93049, Regensburg, Deutschland.

Considering that Quist et al. first described the acute idiopathic scrotal edema (AISE) already in 1956, there are not many studies published in literature concerning the etiology, the development, and the progress of the disease since then. According to the literature the incidence of AISE is about 20%. Read More

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http://dx.doi.org/10.1007/s00120-020-01144-6DOI Listing

Paratesticular colon cancer metastasis in an area of remote trauma.

Authors:
Moshe Wald

BMJ Case Rep 2020 Feb 5;13(2). Epub 2020 Feb 5.

Urology, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA

A 53-year-old man with a history of colon adenocarcinoma and remote scrotal trauma resulting in a palpable nodule. Gradual increase in the size of this lesion over the year prior to his presentation to our clinic prompted scrotal ultrasound that demonstrated a 1.1 cm solid lesion, which appeared to arise from the right epididymal tail. Read More

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http://dx.doi.org/10.1136/bcr-2019-233106DOI Listing
February 2020

Acute scrotum and testicular torsion in children: a retrospective study in a single institution.

J Pediatr Urol 2020 Feb 27;16(1):55-60. Epub 2019 Nov 27.

Department of Pediatric Surgery, Juntendo University Urayasu Hospital, 2-1-1, Tomioka, Urayasu-shi, Chiba, 279-0021, Japan.

Introduction: Testicular torsion (TT), as per the reported incidences in children and preadolescents, is an emergency medical condition that requires prompt surgical treatment. In cases of TT, early and accurate diagnosis of acute scrotum (AS) is important to preserve testicular fertility. In this study, the authors aimed to determine the incidence, clinical examination, etiology, clinical predictors, and treatment of patients with AS and TT. Read More

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http://dx.doi.org/10.1016/j.jpurol.2019.11.007DOI Listing
February 2020

Overview of ultrasound applications for assessing scrotal disorders.

J Ultrasound Med 2020 Jun 16;39(6):1047-1056. Epub 2019 Dec 16.

Department of Radiology, Ludwig-Maximilians-University Munich, Grosshadern Campus, Munich, Germany.

The scrotum may be affected by a plethora of different disorders such as infections, vasculopathies, trauma, and manifestations of primary and secondary malignant masses. In addition to the patient's medical history and clinical examination, ultrasound represents the imaging modality of choice to assess scrotal disorders. Time-consuming contrast-enhanced ultrasound and elastography can provide further information to distinguish between benign and malignant testicular mass lesions. Read More

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http://dx.doi.org/10.1002/jum.15197DOI Listing

Emergency Department Approach to Testicular Torsion: Two Illustrative Cases.

Cureus 2019 Oct 22;11(10):e5967. Epub 2019 Oct 22.

Emergency Medicine, Envision Physician Services, Orlando, USA.

We present two cases of young men with spontaneous nontraumatic testicular pain. While the differential diagnosis for scrotal or testicular pain can include less urgent causes, such as epididymitis, hydrocele, referred pain, idiopathic scrotal edema, and inguinal hernia, for example, the most feared etiology for acute scrotal pain is testicular torsion. The fact that a testicle can torse and detorse is also a confounding factor. Read More

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http://dx.doi.org/10.7759/cureus.5967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863585PMC
October 2019

Comparison of low-power magnification one-layer vasovasostomy with stent and microscopic two-layer vasovasostomy for vasectomy reversal.

Int J Impot Res 2019 Dec 2. Epub 2019 Dec 2.

Department of Urology, Minimally Invasive Urology of Shenzhen Research and Development Center of Medical Engineering and Technology, Shenzhen People's Hospital, Second Clinic Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, 518020, China.

This study aimed to evaluate a simplified vasovasostomy procedure that shortens the operative time. This was a retrospective (non-randomized) study of men who underwent bilateral vasectomy and consulted for vasovasostomy (02/2014-08/2016). Eight interrupted sutures were used for one-layer full-thickness vasal anastomosis over a 20 or 22 G catheter temporarily inserted in the lumen of the anastomotic site as a stent. Read More

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http://dx.doi.org/10.1038/s41443-019-0216-xDOI Listing
December 2019

Region-specific transcriptomic and functional signatures of mononuclear phagocytes in the epididymis.

Mol Hum Reprod 2020 01;26(1):14-29

Program in Membrane Biology, Center for Systems Biology and Division of Nephrology, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.

In the epididymis, prevention of autoimmune responses against spermatozoa and simultaneous protection against pathogens is important for male fertility. We have previously shown that mononuclear phagocytes (MPs) are located either in the epididymal interstitium or in close proximity to the epithelium. In the initial segments (IS), these 'intraepithelial' MPs extend slender luminal-reaching projections between epithelial cells. Read More

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http://dx.doi.org/10.1093/molehr/gaz059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992890PMC
January 2020

Imaging of the acute scrotum: keys to a rapid diagnosis of acute scrotal disorders.

Abdom Radiol (NY) 2020 Jul;45(7):2063-2081

Section of Abdominal Imaging, Imaging Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.

Imaging of the scrotum in the setting of acute symptoms such as pain or swelling is commonly performed emergently to differentiate between patients who require immediate surgery and those that do not. Acute scrotal symptoms are generally caused by infectious, traumatic or vascular etiologies. Rapid diagnosis and initiation of treatment is vital for testicular salvage in cases of acute testicular torsion, testicular rupture, and Fournier gangrene. Read More

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http://dx.doi.org/10.1007/s00261-019-02333-4DOI Listing

A Rare Case of Epididymal Cyst Due to Schistosomiasis.

Cureus 2019 Sep 25;11(9):e5755. Epub 2019 Sep 25.

Pathology, Fortis Escorts Hospital, Faridabad, IND.

Schistosomal epididymitis is a very rare condition. Worldwide, very few cases have been reported, especially in India. Here is a case of schistosomal epididymitis that was found on histopathological examination of an epididymal cyst in a 32-year-old man in India. Read More

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http://dx.doi.org/10.7759/cureus.5755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825452PMC
September 2019

Fine needle aspiration cytology of epididymal nodules and its corroboration with ultrasonographic-histological findings.

Diagn Cytopathol 2020 Feb 7;48(2):118-127. Epub 2019 Nov 7.

Department of Pathology, Sonoscan Healthcare, Malda, West Bengal, India.

Background: Fine needle aspiration cytology (FNAC) assisted with scrotal ultrasonography is the best preoperative diagnostic modality for palpable epididymal nodules. It also aids in their successive remedial approach as well as serves semi-therapeutically in cystic lesions. The objectives of this study are to recognize the spectrum of pathological conditions giving rise to epididymal nodules, then to compare them with corresponding ultrasound images, and to evaluate the histological features wherever practicable. Read More

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http://dx.doi.org/10.1002/dc.24336DOI Listing
February 2020

Unusual intrascrotal lesions in adults in urological practice.

Arch Esp Urol 2019 Nov;72(9):955-964

Departamento de Urología. Hospital de la Universidad de Yüksek Ihtisas Koru Ankara. Ankara. Turquía.

Objective: Unusual intrascrotal lesions in adults generally have been described as case reports in the medical literature. We present two lesions observed in two clinics over more than 28 years, with their radiological, pathological and clinical characteristics.

Methods: Retrospective study preformed between 1989 and 2017 in 446 patients undergoing inguinal orchiectomy. Read More

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November 2019

Damaged male germ cells induce epididymitis in mice.

Asian J Androl 2019 Nov 1. Epub 2019 Nov 1.

Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing 100005, China.

Epididymitis can be caused by infectious and noninfectious etiological factors. While microbial infections are responsible for infectious epididymitis, the etiological factors contributing to noninfectious epididymitis remain to be defined. The present study demonstrated that damaged male germ cells (DMGCs) induce epididymitis in mice. Read More

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http://dx.doi.org/10.4103/aja.aja_116_19DOI Listing
November 2019

Testicular ischemia secondary to epididymo-orchitis: A case report.

Urol Case Rep 2019 Nov 19;27:100893. Epub 2019 Apr 19.

Urology Department, King Fahd Specialist Hospital, Buraidah, Saudi Arabia.

Testicular infarction is a common urological emergency in clinical practice, it is still underreported when it results from other than spermatic cord torsion. It rarely arises from other pathological processes like vasculitis and infectious disease. We report a case of 18-year-old with epididymo-orchitis complicated by testicular ischemia. Read More

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http://dx.doi.org/10.1016/j.eucr.2019.100893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819811PMC
November 2019
1 Read

More Than Just Torsion: An Unusual Case of Testicular Pain.

Mil Med 2020 Jun;185(5-6):e900-e903

Naval Medical Center Portsmouth, 620 John Paul Jones Circle, Portsmouth, VA 23708.

Testicular pain has a wide differential and the nonspecific presentation should be triaged rapidly for urgent diagnosis and treatment. Scrotal pyoceles are uncommon collections of purulent fluid between the visceral and parietal tunica vaginalis, usually secondary to acute epididymo-orchitis, intra-abdominal infection, or trauma. Epididymitis and epididymo-orchitis are generally secondary to sexually transmitted infections or urinary tract pathogens. Read More

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http://dx.doi.org/10.1093/milmed/usz316DOI Listing
June 2020
2 Reads

Comparisons of cancer detection rate and complications between transrectal and transperineal prostate biopsy approaches - a single center preliminary study.

BMC Urol 2019 Oct 28;19(1):101. Epub 2019 Oct 28.

Department of Urology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No.123, Dapi Rd., Niaosong Dist., Kaohsiung, Taiwan, Republic of China.

Background: Prostate biopsy remains the gold standard approach to verify prostate cancer diagnosis. Transrectal (TR) biopsy is a regular modality, while transperineal (TP) biopsy is an alternative for the patients who display persistently high levels of prostate-specific antigen (PSA) and thus have to undergo repeat biopsy. This study aimed to compare the cancer detection rates between TR and TP approaches and assess the post-bioptic complications of the two procedures. Read More

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http://dx.doi.org/10.1186/s12894-019-0539-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816188PMC
October 2019

Pyuria and Post-Operation Urinary Tract Infection after Diode Laser Vaporesection of the Prostate.

Surg Infect (Larchmt) 2020 Apr 17;21(3):255-261. Epub 2019 Oct 17.

Department of Urology, Chung Shan Medical University Hospital, Taichung, Taiwan.

Monopolar transurethral resection of prostate (m-TURP) remains the gold standard for benign prostate obstruction (BPO). Recently developed laser surgical technique provides fewer peri-operative complications with equivalent outcomes. Diode laser vaporesection (DiLRP) offers better hemostasis, shorter catheterization duration, and shorter hospital stay, however, deep thermal penetration might cause prolonged prostatic urethra inflammation and subsequent complications. Read More

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http://dx.doi.org/10.1089/sur.2019.117DOI Listing
April 2020
3 Reads

A Dutch Case Report of Successful Treatment of Chronic Relapsing Urinary Tract Infection with Bacteriophages in a Renal Transplant Patient.

Antimicrob Agents Chemother 2019 12 20;64(1). Epub 2019 Dec 20.

Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands.

We report a case of a 58-year-old renal transplant patient who developed a recurrent urinary tract infection with an extended-spectrum β-lactamase (ESBL)-positive strain in the first month posttransplant. Even though it tested susceptible to carbapenems and despite repeated meropenem treatment, his infection recurred. The infection eventually evolved into epididymitis that was successfully treated with meropenem and bacteriophages. Read More

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http://dx.doi.org/10.1128/AAC.01281-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187595PMC
December 2019
4.476 Impact Factor

Epididymo-orchitis masquerading as an irreducible inguinal hernia.

Br J Hosp Med (Lond) 2019 Oct;80(10):616-617

Consultant Urologist, Nepean Urology Research Group, Department of Urology, Nepean Hospital, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.12968/hmed.2019.80.10.616DOI Listing
October 2019
1 Read

[A young man with a painful scrotum].

Ned Tijdschr Geneeskd 2019 10 3;163. Epub 2019 Oct 3.

Medisch Centrum Leeuwarden, afd. Spoedeisende Hulp, Leeuwarden.

A 16-year-old male patient with no known medical history presented at the Emergency Department (ED) with a 2-day history of pain and swelling in his right hemiscrotum. He was diagnosed with non-bacterial epididymitis and discharged home with medical advice. Six days after being diagnosed, the pain and swelling worsened and he was seen by a general practitioner who concluded that the symptoms were attributable to the previously diagnosed epididymitis. Read More

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October 2019

Melatonin protects against lipopolysaccharide-induced epididymitis in sheep epididymal epithelial cells in vitro.

Immunol Lett 2019 10 3;214:45-51. Epub 2019 Sep 3.

College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, China. Electronic address:

Melatonin has protective effects against inflammation but its role in epididymitis is unknown. We addressed this in the present study using lipopolysaccharide (LPS)-stimulated sheep epididymal epithelial cells as an in vitro inflammation model. We found that interleukin (IL)-1β, IL-6, tumor necrosis factor α, and cyclooxygenase (COX)-2 mRNA levels; COX-2 and Toll-like receptor (TLR)-4 protein levels; and nuclear factor (NF)-κB p65 phosphorylation were increased by LPS treatment. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01652478193027
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http://dx.doi.org/10.1016/j.imlet.2019.09.001DOI Listing
October 2019
6 Reads

Case Report: Epididymo-Orchitis due to .

Am J Trop Med Hyg 2019 11;101(5):1070-1072

Travel and Tropical Medicine Center, HealthPartners, Minneapolis, Minnesota.

Genitourinary tuberculosis (TB) is a rare but well-described form of extrapulmonary TB. We present a case of a 35-year-old man from Ethiopia with scrotal swelling and fever who was found to have epididymo-orchitis due to . The patient presented to the hospital multiple times before undergoing operative debridement with fine needle aspiration and tissue biopsy to confirm the diagnosis. Read More

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http://dx.doi.org/10.4269/ajtmh.19-0162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838570PMC
November 2019
1 Read

False-positive halo sign on testicular scintigraphy in a 2-year-old boy with epididymo-orchitis.

Nucl Med Rev Cent East Eur 2019 ;22(2):94-95

Pain Research Center Imam Khomeini Hospital Ahvaz Jundishapur University Of Medical Science, Ahvaz, Iran.

We reported a case of 2-year-old child where epididymo-orchitis was misdiagnosed as testicular torsion on scrotal scintigraphy. The scan showed that left hemiscrotum demonstrated a rim of increased activity with a photopenic center in the left testis (halo sign). At surgery, epididymo-orchitis was detected and there was no testicular torsion. Read More

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http://dx.doi.org/10.5603/NMR.2019.0023DOI Listing
January 2020
1 Read