Anti-Type VII Collagen Antibodies Are Identified in a Subpopulation of Bullous Pemphigoid Patients With Relapse.
- Delphine Giusti,
- Grégory Gatouillat,
- Sébastien Le Jan,
- Julie Plée,
- Philippe Bernard,
- Frank Antonicelli,
- Bach-Nga Pham
Front Immunol 2018 21;9:570. Epub 2018 Mar 21.
Laboratory of Dermatology, Faculty of Medicine, University of Reims Champagne-Ardenne, Reims, France.
Bullous pemphigoid (BP) is an autoimmune bullous skin disease characterized by anti-BP180 and anti-BP230 autoantibodies (AAbs). Mucous membrane involvement is an uncommon clinical feature of BP which may evoke epidermolysis bullosa acquisita, another skin autoimmune disease characterized by anti-type VII collagen AAbs. We therefore evaluated the presence of anti-type VII collagen AAbs in the serum of BP patients with and without mucosal lesions at time of diagnosis and under therapy. Read More