5,238 results match your criteria Epidermal Inclusion Cyst

Hair-Bearing Human Skin Organoids from Pluripotent Stem Cells: A Novel Source of Advanced Skin Substitutes for Wound Repair.

FASEB J 2022 May;36 Suppl 1

Department of Otolaryngology, Boston Children's Hospital, Boston, MA.

Cutaneous injuries represent a major clinical challenge domestically and globally. Indeed, chronic wounds are estimated to affect the quality of life of nearly 2.5% of the United States population, and diabetic foot ulcers have a lethality nearly equivalent to that of all cancers combined. Read More

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Top Advances in Dermatologic Ultrasound.

Ximena Wortsman

J Ultrasound Med 2022 May 10. Epub 2022 May 10.

Institute for Diagnostic Imaging and Research of the Skin and Soft Tissues, Santiago, Chile.

The advances in dermatologic ultrasound have been significantly influenced by the development of high- and ultrahigh-frequency probes, the provision of guidelines for performing the examinations, and a growing number of publications in the field. This review analyzes the most significant contributions that have impacted the daily practice of dermatologists in recent years. This includes the advances in anatomical detection and the patterns of benign and malignant cutaneous tumors, inflammatory dermatologic conditions, vascular anomalies, nail abnormalities, and aesthetic procedures. Read More

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Epidermoid Cyst of the Cavum Septum Pellucidum: A Case Report and Literature Review.

Neurol India 2022 Mar-Apr;70(2):832-833

Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

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Expression of BMP4 and FOXN1 in orthokeratinized odontogenic cyst compared to odontogenic keratocyst suggests an epidermal phenotype.

Biotech Histochem 2022 May 9:1-9. Epub 2022 May 9.

Department of Oral Medicine and Pathology and Hospital Dentistry, National and Kapodistrian University of Athens, Athens, Greece.

Odontogenic keratocysts (OKC) and orthokeratinized odontogenic cysts (OOC) are odontogenic cysts that share histological and immunohistochemical similarity with epidermal appendages and cutaneous cystic lesions despite exhibiting contrasting biological behavior. In epidermal appendages, BMP4 induces expression of FOXN1, which participates in terminal differentiation of keratinocytes and control of proliferation. We compared BMP4 and FOXN1 expression in OOC and OKC to investigate their role in the epithelial differentiation of these cysts. Read More

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Epidermoid cyst in an intrapancreatic accessory spleen with abnormally high CEA level in cyst fluid: a case report.

Autops Case Rep 2022 14;12:e2021369. Epub 2022 Apr 14.

United Christian Hospital, Department of Pathology, Hong Kong, China.

Epidermoid cyst in an intrapancreatic accessory spleen is a rare benign lesion that is difficult to diagnose preoperatively. Cyst fluid analysis for biochemistry markers has been widely used to aid the diagnosis of pancreatic cysts. A high cyst fluid carcinoembryonic antigen (CEA) level (>800 ng/mL) is said to be useful in distinguishing intraductal papillary mucinous neoplasm (IPMN) and mucinous cystic neoplasm (MCN) from other non-mucinous cysts. Read More

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Activation of the EGFR/MAPK pathway drives transdifferentiation of quiescent niche cells to stem cells in the testis niche.

Elife 2022 04 25;11. Epub 2022 Apr 25.

Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, United States.

Adult stem cells are maintained in niches, specialized microenvironments that regulate their self-renewal and differentiation. In the adult testis stem cell niche, somatic hub cells produce signals that regulate adjacent germline stem cells (GSCs) and somatic cyst stem cells (CySCs). Hub cells are normally quiescent, but after complete genetic ablation of CySCs, they can proliferate and transdifferentiate into new CySCs. Read More

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A Case of Surgically Treated Epidermal Cyst En Plaque of Scrotum.

Ann Dermatol 2022 Apr 24;34(2):152-153. Epub 2022 Mar 24.

Department of Dermatology, Chosun University College of Medicine, Gwangju, Korea.

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Mucoepidermoid carcinoma - A common neoplasm at an unusual site, mimicking a benign cyst on cytology: Diagnostic pitfall!

J Oral Maxillofac Pathol 2022 Feb 28;26(Suppl 1):S30-S33. Epub 2022 Feb 28.

Department of Pathology, Kasturba Medical College, Manipal, Karnataka, India.

Mucoepidermoid carcinoma (MEC) is known to be a relatively common neoplasm of the major and minor salivary glands that can secondarily involve skin. The clinical manifestations, diagnostic cytology and histopathology of MEC presenting as a clinically benign periauricular cystic nodule have been analyzed. The challenge of accurate diagnosis can be illustrated by the fact that initially, on cytology, this tumor was misdiagnosed as a benign epidermal inclusion cyst due to the presence of mucin-filled cells which were misinterpreted as cyst macrophages. Read More

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February 2022

Basal cell carcinoma derived from epidermal cyst of the knee of a patient with xeroderma pigmentosum group C.

J Dermatol 2022 Apr 12. Epub 2022 Apr 12.

Department of Dermatology, Graduate School of Medicine, Kobe University, Kobe, Japan.

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Identification of Codon 146 Variants in Isolated Epidermal Nevus and Multiple Lesions in Oculoectodermal Syndrome: Confirmation of the Phenotypic Continuum of Mosaic RASopathies.

Int J Mol Sci 2022 Apr 6;23(7). Epub 2022 Apr 6.

Center for Medical Genetics Ghent, Ghent University Hospital, 9000 Ghent, Belgium.

Mosaic RASopathies are a molecularly heterogeneous group of (neuro)cutaneous syndromes with high phenotypical variability. Postzygotic variants in have been described in oculoectodermal syndrome (OES), encephalocraniocutaneous lipomatosis (ECCL) and epidermal nevus syndrome (ENS). This study confirms the continuum of mosaic neurocutaneous RASopathies showing codon 146 variants in an individual with OES and, for the first time, in an individual with (isolated) epidermal nevus. Read More

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Primary Splenic Epidermoid Cyst: A Case Report.

Cureus 2022 Mar 3;14(3):e22799. Epub 2022 Mar 3.

General Surgery, Ross University School of Medicine, Atlanta, USA.

Primary splenic epidermal cysts, a type I splenic lesion, are very uncommon and usually found coincidentally. In this report, we present a primary splenic epidermal cyst that presented as a mass in the left upper quadrant associated with sharp pain, early satiety, and constipation. We review the classification of splenic cysts with a detailed look into the causes and types of type I cysts. Read More

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Intrasellar epidermoid cyst. A case report.

Endocrinol Diabetes Nutr (Engl Ed) 2022 03 16;69(3):227-229. Epub 2022 Feb 16.

Servicio de Endocrinología, Hospital Universitario La Paz, Madrid, Spain.

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Umbilical epidermal inclusion cysts, an unusual cause of umbilical mass following laparoscopic surgery: case report.

J Surg Case Rep 2022 Mar 22;2022(3):rjac059. Epub 2022 Mar 22.

Department of General Surgical Specialties, Royal Melbourne Hospital, Parkville, Australia.

Umbilical lumps are a common presentation that can represent a diagnostic challenge as the differentials are broad. Epidermal inclusion cysts occur when epidermal cells are implanted in the dermis following trauma, or surgery. Although epidermal inclusion cysts are common, they are rarely cause of umbilical mass, with less than 10 cases described in the literature. Read More

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Imaging findings of malignant skin tumors: radiological-pathological correlation.

Insights Imaging 2022 Mar 22;13(1):52. Epub 2022 Mar 22.

Department of Radiology, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.

Sometimes, radiologists encounter malignant skin tumors (MSTs) during image interpretation. As MSTs require different clinical management modalities for each histological subtype, accurate preoperative diagnosis is essential. The histological subtypes of MST can be easily assessed by visual inspection or biopsy. Read More

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Searching beyond nevi - A rare case of neurocutaneous ocular syndrome.

Orbit 2022 Mar 17:1-5. Epub 2022 Mar 17.

Department of Orbit and Oculoplasty, Aravind Eye Hospital and PG Institute of Ophthalmology, Madurai, India.

Epidermal nevus syndrome is a rare congenital disorder affecting only a few hundred people in the world. It has ophthalmic, dermatological, and neurological manifestations, with varied presentation. Here, we report a case of two-year-old child who presented with epibulbar mass in left eye, pigmented nevi over left side of the body and alopecia over left side of parieto-temporal scalp. Read More

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Surgical management of large, connected perineal and pelvic epidermal inclusion cysts mimicking a dumbbell-shaped lesion in an adult male.

Int J Surg Case Rep 2022 Apr 9;93:106932. Epub 2022 Mar 9.

Department of Surgery, University of Iowa Carver College of Medicine, 375 Newton Rd, Iowa City, IA 52242, USA. Electronic address:

Introduction And Importance: Epidermal inclusion cysts are a common benign finding, and they are predominantly asymptomatic. They can rarely form in the pelvis or abdomen, however, and may cause symptoms secondary to mass effect. This case highlights management of an anterectal epidermal inclusion cyst connected to the perineal cyst, mimicking a dumbbell-shaped lesion, found in a male. Read More

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Leiomyoma with bizarre nuclei of the scrotum: a rare entity.

BMJ Case Rep 2022 Mar 9;15(3). Epub 2022 Mar 9.

Pathology Department, Centro Hospitalar e Universitário de Coimbra EPE, Coimbra, Portugal.

Leiomyomas of the paratesticular region are a rare entity. A subtype of leiomyomas called bizarre nuclei leiomyoma is even rarer and histologically present some interesting features that are important to recognise to make the differential diagnosis with its malignant counterpart-leiomyosarcoma. We present a case of a man in his 60s, who presented with a painless mass on the right testicle. Read More

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Delayed Postoperative Hemorrhage in Epidermoid Tumors: A Unique and Catastrophic Complication.

Neurol India 2022 Jan-Feb;70(1):462-463

Department of Neurosurgery, RMLIMS, Lucknow, Uttar Pradesh, India.

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[Testicular Preservation in a Patient with a Testicular Epidermoid Cyst Achieved by Preoperative Diagnosis : A Case Report].

Hinyokika Kiyo 2022 Feb;68(2):67-70

The Departments of Urology, Ohara HealthCare Foundation Kurashiki Central Hospital.

Testicular epidermoid cysts are relatively rare, accounting for about 1% of all testicular tumors, and are often treated by high orchiectomy. We describe here the case of a testicular epidermoid cyst treated by testicle-sparing surgery due to a preoperative diagnosis. A 23-year-old man complained of a painless mass in the right scrotum. Read More

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February 2022

Management of Soft-tissue Tumors With a Size of 2-5 cm, Including Malignancy.

Anticancer Res 2022 Mar;42(3):1555-1562

Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.

Background/aim: The management of soft-tissue tumors of 2-5 cm is not specified. We investigated the management of these cases.

Patients And Methods: Among 105 cases with soft-tissue tumors from 2014 to 2021, 38 with tumors of 2-5 cm were retrospectively reviewed. Read More

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Diagnostic Challenge in Rapidly Growing Langerhans Cell Histiocytosis with Aneurysmal Bone Cyst in the Maxilla: A Case Report.

Diagnostics (Basel) 2022 Feb 3;12(2). Epub 2022 Feb 3.

Department of Pathology, Kyung Hee University College of Medicine, Kyung Hee University Hospital, #23 Kyunghee-daero, Dongdaemun-gu, Seoul 02447, Korea.

Langerhans cell histiocytosis (LCH) is a rare neoplastic disorder characterized by the clonal proliferation of CD1a +/CD 207 + dendritic cells, whose features are similar to those of epidermal Langerhans cells. LCH is more common in children than in adults. Localized osteolytic lesions in the craniofacial bones are the most common manifestations of LCH. Read More

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February 2022

Expression of epithelial growth factors and of apoptosis-regulating proteins, and presence of CD57+ cells in the development of inflammatory periapical lesions.

J Appl Oral Sci 2022 21;30:e20210413. Epub 2022 Feb 21.

Universidade Estácio de Sá, Programa de Pós-Graduação em Odontologia, Rio de Janeiro, RJ, Brasil.

Objective: The mechanisms that stimulate the proliferation of epithelial cells in inflammatory periapical lesions are not completely understood and the literature suggests that changes in the balance between apoptosis and immunity regulation appear to influence this process.To evaluate the expression of the epidermal growth factor (EGF), its receptor (EGFR) and of the keratinocyte growth factor (KGF), the presence of CD57+ cells, the epithelial cell proliferation index, and the expression of the Bcl-2 protein in inflammatory periapical lesions (IPL) at different stages of development.

Methodology: Our sample was composed of 52 IPLs (22 periapical granulomas - PG - and 30 periapical cysts - PC), divided into three groups: PGs, small PCs, and large PCs. Read More

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February 2022

Lip Epidermoid Cyst Caused by a Piercing: A Report of a Rare Case.

Case Rep Dent 2022 8;2022:8015990. Epub 2022 Feb 8.

Department of Oral and Maxillofacial Surgery, Faculty of Medicine, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki 305-8575, Japan.

We report the case of a lip epidermoid cyst, caused by piercing in a 23-year-old Japanese woman. She had an exophytic lesion in the lower lip associated with the piercing which was initially diagnosed as a mucous retention cyst. The lesion was resected under local anesthesia, and pathological examination revealed an epidermoid cyst, likely caused by piercings. Read More

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February 2022

Intrapancreatic accessory spleen with an epidermoid cyst: a malignant mimicry.

BMJ Case Rep 2022 Feb 14;15(2). Epub 2022 Feb 14.

General Surgery, Tan Tock Seng Hospital, Singapore.

With the liberal use of CT scan for clinical diagnosis, clinicians are faced with an increasing number of pancreatic incidentalomas. Compared with other incidentalomas, pancreatic incidentalomas have higher chances of future malignant transformation. There are many differential diagnoses, and epidermoid cyst in an intrapancreatic accessory spleen (ECIPAS) is extremely rare, with only a handful of reports. Read More

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February 2022

Correlation of radiological features of white epidermoid cysts with histopathological findings.

Sci Rep 2022 02 10;12(1):2314. Epub 2022 Feb 10.

Kingston Health Sciences Centre, Queen's University, Kingston, Canada.

Epidermoid cysts are benign congenital extra-axial lesions commonly found in the posterior fossa. These lesions have a characteristic imaging appearance on computed tomography (CT) scan and magnetic resonance imaging (MRI), but occasionally they may exhibit atypical radiological features, showing unusual hyperintensity on T1-weighted images (T1WI). Currently, such atypical appearance is referred to as white epidermoid. Read More

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February 2022

A Novel Presentation of Nasal Steatocystoma Simplex: A Case Report and Literature Review.

JAMA Otolaryngol Head Neck Surg 2022 Apr;148(4):380-381

Department of Otolaryngology-Head and Neck Surgery, Tallaght University Hospital, Dublin, Ireland.

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Imaging of synchronous multiple primary lung adenocarcinoma with concomitant and mutations: a case report and review of the literature.

Transl Cancer Res 2021 May;10(5):2509-2515

Department of Diagnostic Radiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

With the application of computed tomography (CT) imaging technology, the incidence rate of multiple primary lung cancer has gradually increased. However, the prevalence of concomitant epidermal growth factor receptor () and Kirsten rat sarcoma viral oncogene () mutations in patients with non-small cell lung cancer (NSCLC) is low, and cases of concomitant and mutations have rarely been reported. In this case, we report a 71-year-old male patient with multiple primary lung adenocarcinoma harboring different gene mutation subtypes of and . Read More

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Two Cases of Malignant Proliferating Trichilemmal Tumor (MPTT) and Review of Literature.

R I Med J (2013) 2022 Feb 1;105(1):12-16. Epub 2022 Feb 1.

Department of Dermatology, The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

Malignant proliferating trichilemmal tumors (MPTTs, malignant proliferating pilar tumors) are theorized to originate from the outer root sheath of the hair follicle which resembles the isthmic portion of the hair follicle and epithelium of the lower hair follicle in catagen phase.1 They may develop de novo or arise from a pre- existing trichilemmal cyst or proliferating trichilemmal tumor. The tumors typically present with rapid growth on the scalps of women over the age of 50. Read More

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February 2022

Melanoma arising in an epidermal inclusion cyst presenting as discharging sinus: A rare case report.

Indian J Pathol Microbiol 2022 Jan-Mar;65(1):235-237

Department of Pathology and Surgery, Maulana Azad Medical College and Associated Hospitals, New Delhi, India.

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February 2022

Tacrolimus-induced Epidermoid Cysts in the Renal Transplant Patient.

Indian J Nephrol 2021 Nov-Dec;31(6):571-573. Epub 2021 Nov 9.

Department of Nephrology, Sir Ganga Ram Hospital, New Delhi, India.

Epidermal cysts are common benign cystic lesions that occur mostly sporadically. Common sites involved are arms, face, and trunk. The cyst may progress slowly and remain for years. Read More

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November 2021