7,784 results match your criteria Epidemiologic Perspectives & Innovations [Journal]


Prostate care and prostate cancer from the perspectives of undiagnosed men: a systematic review of qualitative research.

BMJ Open 2019 Jan 28;9(1):e022842. Epub 2019 Jan 28.

Clinical Registry Unit, Department of Epidemiology and Preventive Medicine, Monash University Australia, Melbourne, Victoria, Australia.

Objectives: To summarise and evaluate evidence from men who had not been diagnosed with prostate cancer about their perspectives on prostate care and prostate cancer.

Design: A systematic review of qualitative research, on the perspectives of non-cancerous men regarding prostate cancer prevention and care.

Setting: A wide range of settings including primary and secondary care. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-022842DOI Listing
January 2019

Clinical pharmacokinetic and pharmacodynamic analysis of daptomycin and the necessity of high-dose regimen in Japanese adult patients.

J Infect Chemother 2019 Feb 16. Epub 2019 Feb 16.

Division of Infectious Disease and Hospital Epidemiology, Saga University Medical Center, Saga, Japan; Department of International Medicine, Faculty of Medicine, Saga University, Saga, Japan.

The objective of this study was to explore the optimal dosage regimen of daptomycin and to determine the necessity and validity of a high-dose regimen from the perspectives of PK/PD parameters using Monte Carlo Simulation (MCS) and therapeutic drug monitoring (TDM) in a Japanese clinical setting. The volume of distribution (0.13 ± 0. Read More

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http://dx.doi.org/10.1016/j.jiac.2019.01.011DOI Listing
February 2019

Perspectives on the Management of Children in a Biocontainment Unit: Report of the NETEC Pediatric Workgroup.

Health Secur 2019 Jan/Feb;17(1):11-17

H. Dele Davies, MD, is Professor of Pediatric Infectious Diseases and Public Health, Department of Pediatrics, University of Nebraska Medical Center, Omaha NE.

During the outbreak of Ebola virus disease that struck West Africa during 2014-2016, a small handful of expatriate patients were evacuated to specialized high-level containment care units, or biocontainment units, in the United States and Western Europe. Given the lower mortality rate (18% versus 40% for those treated in Africa) among these patients, it is likely that high-level containment care will be used in the future with increasing frequency. It is also likely that children infected with Ebola and other highly hazardous communicable diseases will someday require such care. Read More

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http://dx.doi.org/10.1089/hs.2018.0074DOI Listing
February 2019

Negative Effects of "Predatory" Journals on Global Health Research.

Ann Glob Health 2018 Nov 5;84(4):584-589. Epub 2018 Nov 5.

Department of Mathematics, School of Sciences, Universidad Antonio Narino, CO.

Predatory journals (PJ) exploit the open-access model promising high acceptance rate and fast track publishing without proper peer review. At minimum, PJ are eroding the credibility of the scientific literature in the health sciences as they actually boost the propagation of errors. In this article, we identify issues with PJ and provide several responses, from international and interdisciplinary perspectives in health sciences. Read More

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http://dx.doi.org/10.9204/aogh.2389DOI Listing
November 2018

Reducing waste in nutritional epidemiology: review and perspectives.

Proc Nutr Soc 2019 Feb 19:1-9. Epub 2019 Feb 19.

Department of Food Technology, Safety and Health,Ghent University,Ghent,Belgium.

We discuss efforts in improving the value of nutrition research. We organised the paper in five research stages: Stage 1: research priority setting; Stage 2: research design, conduct and analysis; Stage 3: research regulation and management; Stage 4: research accessibility and Stage 5: research reporting and publishing. Along the stages of the research cycle, varied initiatives exist to improve the quality and added value of nutrition research. Read More

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http://dx.doi.org/10.1017/S002966511900051XDOI Listing
February 2019

Implications of a complexity perspective for systematic reviews and guideline development in health decision making.

BMJ Glob Health 2019 25;4(Suppl 1):e000899. Epub 2019 Jan 25.

Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK.

There is growing interest in the potential for complex systems perspectives in evaluation. This reflects a move away from interest in linear chains of cause-and-effect, towards considering health as an outcome of interlinked elements within a connected whole. Although systems-based approaches have a long history, their concrete implications for health decisions are still being assessed. Read More

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http://gh.bmj.com/lookup/doi/10.1136/bmjgh-2018-000899
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http://dx.doi.org/10.1136/bmjgh-2018-000899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350708PMC
January 2019
1 Read

Cost analysis and provider preferences of low-dose, high-frequency approach to in-service training programs in Uganda.

J Glob Health 2019 Jun;9(1):010416

Jhpiego, an affiliate of Johns Hopkins, Baltimore, Maryland, USA.

Background: Many countries in sub-Saharan Africa still face significant challenges in maternal and child health where low numbers, uneven distribution, and training deficits of the health workforce impede quality care. Low-dose, high-frequency training (LDHF), an innovative approach to in-service training, focuses on competency, team-based repetitive learning and practice in the clinical setting. In Uganda, we conducted cost analyses of local organization LDHF training programs for Post-abortion care (PAC) and Pediatric HIV to assess cost drivers and cost efficiency and compare costs to traditional workshop based training. Read More

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http://dx.doi.org/10.7189/jogh.09.010416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370980PMC

Hierarchical complexity of the adult human structural connectome.

Neuroimage 2019 Feb 14;191:205-215. Epub 2019 Feb 14.

Usher Institute for Population Health Science and Informatics, Medical School, University of Edinburgh, Edinburgh, EH16 4UX, UK.

The structural network of the human brain has a rich topology which many have sought to characterise using standard network science measures and concepts. However, this characterisation remains incomplete and the non-obvious features of this topology have largely confounded attempts towards comprehensive constructive modelling. This calls for new perspectives. Read More

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http://dx.doi.org/10.1016/j.neuroimage.2019.02.028DOI Listing
February 2019

Ovarian carcinosarcoma: Current developments and future perspectives.

Crit Rev Oncol Hematol 2019 Feb 24;134:46-55. Epub 2018 Dec 24.

Gynaecology Unit, General Hospital "G. Hatzikosta", Makrigianni Avenue, 45001, Ioannina, Greece.

Ovarian carcinosarcoma (OCS) constitute uncommon malignancies accounting for only 1-4% of ovarian cancers. Patients more often present with advanced stage disease and symptoms similar to those of epithelial ovarian cancers (EOC). Optimal tumor cytoreduction appears to be an important determinant of survival. Read More

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http://dx.doi.org/10.1016/j.critrevonc.2018.12.006DOI Listing
February 2019

Patient Perspectives on DMARD Safety Concerns in Rheumatology Trials: Results from Inflammatory Arthritis Patient Focus Groups and OMERACT Attendees Discussion.

J Rheumatol 2019 Feb 15. Epub 2019 Feb 15.

Department of Family Medicine, McGill University, Montreal, Canada. Musculoskeletal Statistics Unit, The Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark. Canberra Rheumatology, Canberra, ACT, Australia College of Health and Medicine, Australian National University, Canberra, ACT, Australia; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, NSW, Australia. Patient Partners, Ingersoll, Canada. Division of Rheumatology, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA. Division of Rheumatology, Department of Medicine, Hospital for Special Surgery, New York, NY, USA; Department Social Work Programs, Hospital for Special Surgery, New York, NY USA; Department Social Work Programs, Hospital for Special Surgery, New York, NY USA; Division of Rheumatology, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA; Institute of Bone and Joint Research-Kolling Institute, University of Sydney; Rheumatology Department, Royal North Shore Hospital; Centre for Health Policy, School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia; Northern Health, Epping Victoria. Sydney Medical School, University of Sydney, Sydney, Australia; Institute of Bone and Joint Research, Kolling Institute, Northern Sydney Local Health District, St Leonards, NSW, Australia; Department of Rheumatology, Royal North Shore Hospital, Reserve Road, St Leonards, NSW, 2065, Australia. Clinical Investigator, Ottawa Hospital Research Institute, Ottawa Hospital, Ottawa, Ontario, Canada; Adjunct Professor, School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Division of Rheumatology, Department of Medicine, and School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa; Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa; Professor of Biostatistics and Clinical Epidemiology; Musculoskeletal Statistics Unit, The Parker Institute, Bispebjerg and Frederiksberg Hospital; & Department of Rheumatology, Odense University Hospital, Denmark.Professor, Department of Medicine, McGill University, Montreal, Quebec, Canada Adjunct Professor, Division of Rheumatology, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA. Address correspondence to Dr. Susan J. Bartlett. Email:

Objective: The OMERACT Safety Working Group is identifying core safety domains that matter most to rheumatic disease patients.

Methods: International focus groups were held with 39 inflammatory arthritis patients to identify DMARD experiences and concerns. Themes were identified by pragmatic thematic coding and discussed in small groups by meeting attendees. Read More

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http://dx.doi.org/10.3899/jrheum.181185DOI Listing
February 2019
1 Read

Intersectional decomposition analysis with differential exposure, effects, and construct.

Soc Sci Med 2019 Jan 31. Epub 2019 Jan 31.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

In recent years a wide array of proposals for bringing intersectional perspectives into quantitative studies of health disparities have appeared, from studies of interaction, predictive discrimination, to mediation. Bauer and Scheim, in a companion set of articles, extend these proposals by developing new attribution-blind measures of perceived discrimination and using VanderWeele's 3-way decomposition to quantify its contribution to disparities through differential exposure and differential effects (sometimes called differential vulnerability or susceptibility). In this commentary, after providing an overview of causal inference interpretations with social characteristics, we provide a broad overview of old and new decomposition methods in the social sciences literature and contrast their strengths and weaknesses for studying intersectional inequalities. Read More

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http://dx.doi.org/10.1016/j.socscimed.2019.01.033DOI Listing
January 2019

The Daniel K. Inouye College of Pharmacy Scripts: Perspectives on the Epidemiology of Gout and Hyperuricemia.

Authors:
Youssef M Roman

Hawaii J Med Public Health 2019 Feb;78(2):71-76

Daniel K. Inouye College of Pharmacy, University of Hawai'i at Hilo, Hilo, HI.

Gout is the most common inflammatory arthritic condition affecting more men than women. Hyperuricemia and the deposition of urate crystals into the joints are the hallmarks of gout. The prevalence of gout and hyperuricemia is rising in the United States and world-wide possibly due to the aging population, comorbidities, and other lifestyle factors. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369891PMC
February 2019
1 Read

Scleroderma patient perspectives on social support from close social relationships.

Disabil Rehabil 2019 Feb 14:1-11. Epub 2019 Feb 14.

a Lady Davis Institute for Medical Research, Jewish General Hospital , Montreal , Canada.

Purpose: People with rare diseases must cope with many physical and psychological challenges; an endeavor that can be difficult to carry out without external support. The purpose of this study was to understand how patients with scleroderma perceive the social support they need and receive from close relationships to better manage their disease.

Method: Four focus groups with patients (N = 19) were conducted. Read More

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http://dx.doi.org/10.1080/09638288.2018.1531151DOI Listing
February 2019
1 Read

Transformative learning as pedagogy for the health professions: a scoping review.

Med Educ 2019 Feb 14. Epub 2019 Feb 14.

Warwick Medical School, University of Warwick, Coventry, UK.

Context: Transformative learning (TL) has been described as learning that challenges established perspectives, leading to new ways of being in the world. As a learning theory it has resonated with educators globally, including those in the health professions. Described as a complex metatheory, TL has evolved over time, eliciting divergent interpretations of the construct. Read More

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http://dx.doi.org/10.1111/medu.13804DOI Listing
February 2019
2 Reads

The value and consequences of using public health technology assessments for private payer decision-making in Canada: one size does not fit all.

J Med Econ 2019 Feb 13. Epub 2019 Feb 13.

b McMaster University, Department of Clinical Epidemiology and Biostatistics (CEB) , Hamilton , Ontario , Canada.

Background Both public and private insurers provide drug coverage in Canada. All payers are under pressure to contain costs. It has recently been proposed that private plans leverage the public health technology assessment (HTA) evaluation process in their decision-making. Read More

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http://dx.doi.org/10.1080/13696998.2019.1582535DOI Listing
February 2019

An Overview on Epidemiology of Tuberculosis.

Mymensingh Med J 2019 Jan;28(1):259-266

Dr Mohammad Kamruzzaman Khan, Lecturer, Department of Community Medicine, Mymensingh Medical College (MMC), Mymensingh, Bangladesh; E-mail: kamruz

Tuberculosis (TB) is a progressive granulomatous infectious disease caused by the gram positive, acid fast bacilli classified under the genus Mycobacterium. Tuberculosis in human is mostly by Mycobacterium tuberculosis and primarily affects lungs causing pulmonary tuberculosis. It can also affect intestine, meninges, bones, joints, lymph nodes, skin and other tissues of the body causing extra-pulmonary tuberculosis. Read More

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January 2019
2 Reads

Life Course Socioeconomic Conditions and Frailty at Older Ages.

J Gerontol B Psychol Sci Soc Sci 2019 Feb 7. Epub 2019 Feb 7.

Swiss NCCR "LIVES - Overcoming Vulnerability: Life Course Perspectives", University of Geneva, Switzerland.

Objectives: This paper aimed to assess associations of childhood socioeconomic conditions (CSC) with the risk of frailty in old age and whether adulthood socioeconomic conditions (ASC) influence this association.

Methods: Data from 21 185 individuals aged 50 years and older included in the longitudinal Survey of Health, Ageing, and Retirement in Europe were used. Frailty was operationalized as a sum of presenting weakness, shrinking, exhaustion, slowness, or low activity. Read More

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http://dx.doi.org/10.1093/geronb/gbz018DOI Listing
February 2019
1 Read

Engaging men in an mHealth approach to support postpartum family planning among couples in Kenya: a qualitative study.

Reprod Health 2019 Feb 11;16(1):17. Epub 2019 Feb 11.

Department of Obstetrics and Gynecology, University of Washington, Harborview Medical Center, 325 Ninth Ave., Boxes 359909, Seattle, WA, 98104, USA.

Background: Involving male partners in family planning (FP) education and counseling may improve FP utilization and help meet couples' reproductive health needs in the postpartum period. We aimed to explore Kenyan men's and women's perspectives on an interactive short message service (SMS) approach to support postpartum FP decision-making, and inform intervention content for a randomized controlled trial (RCT).

Methods: We conducted four focus group discussions (FGD) among men (n = 35) and two among pregnant/postpartum women (n = 15) in western Kenya. Read More

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http://dx.doi.org/10.1186/s12978-019-0669-xDOI Listing
February 2019
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Caregivers' Perspectives on the Slight Recovery of Oral Intake of Home-Dwelling Patients Living With a Percutaneous Endoscopic Gastrostomy Tube: A Qualitative Study Using Focus Group Interviews.

Nutr Clin Pract 2019 Feb 11. Epub 2019 Feb 11.

Gerodontology and Oral Rehabilitation, Department of Gerontology and Gerodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

Background: Swallowing rehabilitation for patients living with a percutaneous endoscopic gastrostomy (PEG) tube for home enteral nutrition (HEN) is poorly documented, and the quality of caregivers' daily lives is also unknown.

Methods: A qualitative study based on constant comparative analysis was conducted. The study subjects were the caregivers of acquired brain injury survivors residing at home and living with a PEG tube for HEN who had recovered slight oral intake because of swallowing rehabilitation. Read More

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http://dx.doi.org/10.1002/ncp.10253DOI Listing
February 2019

Dental opinion leaders' perspectives on barriers and facilitators to HPV-related prevention.

Hum Vaccin Immunother 2019 Feb 8:1-7. Epub 2019 Feb 8.

a College of Public Health , University of South Florida , Tampa , FL , USA.

Evidence suggests a causal connection between the Human Papillomavirus (HPV) and oropharyngeal cancers. HPV-related oropharyngeal cancers are increasing and are the most common HPV-associated cancer. Previous research suggests that dental professionals recognize a role in the prevention of HPV and oropharyngeal cancers. Read More

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http://dx.doi.org/10.1080/21645515.2019.1565261DOI Listing
February 2019
4 Reads

Parental perspectives on provider adherence to AAN epilepsy quality measures in rural and urban tertiary care centers.

Epilepsy Behav 2019 Feb 4;92:256-259. Epub 2019 Feb 4.

Children's National Health System, Center for Neuroscience, 111 Michigan Avenue NW, Washington, DC 10010, USA. Electronic address:

Several American Academy of Neurology (AAN) epilepsy practice guidelines recommend conversations that neurologists should have with patients and their parents. We sought to determine whether parents of pediatric patients with epilepsy had knowledge of epilepsy quality measures (EQMs) and whether they recalled having discussions with their child's neurologist about each of the EQM. Surveys were distributed to parents at five clinic sites associated with epilepsy centers in Washington, DC and Charlottesville, Virginia. Read More

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http://dx.doi.org/10.1016/j.yebeh.2019.01.009DOI Listing
February 2019
1 Read

Administrators, health service providers, and consumers perspectives of functions of district health-care systems in Oromia region, Ethiopia: A qualitative study.

Int J Health Plann Manage 2019 Feb 6. Epub 2019 Feb 6.

School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia.

The practice of functions of district health-care systems in Ethiopia is not clear. The aim of this study was to investigate the perspectives of administrators, health service providers, and health-care consumers regarding functions of district health-care systems as currently practiced. Grounded theory approach was applied using interviews and desk review of documents. Read More

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http://dx.doi.org/10.1002/hpm.2742DOI Listing
February 2019

[From Alma-Ata to the digital citizen: towards a digital primary health care in Peru].

Rev Peru Med Exp Salud Publica 2018 Oct-Dec;35(4):678-683

Instituto de Gobierno y de Gestión Pública. Universidad de San Martín de Porres. Lima, Perú.

The countries of the Region of the Americas Numerous have experienced many changes since the Declaration of AlmaAta in 1978, such as globalization, new epidemiologic and demographic profiles, and the information and communication technology revolution. Nevertheless, the primary health care models in many countries of the region still endure numerous challenges, including the disarticulation of the levels of care and an inefficient management of information. It is urgent to implement a strong, flexible, and interoperable health information system that would allow the suitable access to precise, reliable, and consistent information about the health of the population. Read More

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http://dx.doi.org/10.17843/rpmesp.2018.354.3710DOI Listing

Health Care Professionals' Perceptions of Home Telemonitoring in Heart Failure Care: Cross-Sectional Survey.

J Med Internet Res 2019 Feb 6;21(2):e10362. Epub 2019 Feb 6.

Centre for Patient-Centered Heart and Lung Research, Department of Cardiothoracic Surgery, Oslo University Hospital Ullevål, Oslo, Norway.

Background: Noninvasive telemonitoring (TM) can be used in heart failure (HF) patients to perform early detection of decompensation at home, prevent unnecessary health care utilization, and decrease health care costs. However, the evidence is not sufficient to be part of HF guidelines for follow-up care, and we have no knowledge of how TM is used in the Nordic Baltic region.

Objective: The aim of this study was to describe health care professionals' (HCPs) perception of and presumed experience with noninvasive TM in daily HF patient care, perspectives of the relevance of and reasons for applying noninvasive TM, and barriers to the use of noninvasive TM. Read More

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http://dx.doi.org/10.2196/10362DOI Listing
February 2019
2 Reads

Dynamic perspectives on the search for a universal influenza vaccine.

J Infect Dis 2019 Jan 31. Epub 2019 Jan 31.

Department of Ecology and Evolutionary Biology, Princeton University.

A universal influenza vaccine (UIV) could considerably alleviate the public health burden of both seasonal and pandemic influenza. While significant progress has been achieved in clarifying basic immunology and virology relating to UIV, a number of important questions relating to the dynamics of infection, immunity, and pathogen evolution remain unsolved. Here, we review these gaps, which span integrative levels, from cellular to global and timescales from molecular events to decades. Read More

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http://dx.doi.org/10.1093/infdis/jiz044DOI Listing
January 2019

Monogenean fauna of alien tilapias (Cichlidae) in south China.

Parasite 2019 4;26. Epub 2019 Feb 4.

State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory for Improved Variety Reproduction of Aquatic Economic Animals, and Research Center for Parasitic Organisms, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China.

Tilapias are important aquaculture fishes that have been introduced widely all over the world, often carrying their monogenean parasites with them. An extensive investigation on monogeneans of invasive tilapias was conducted in 19 natural water sources in south China between July 2015 and December 2017. We found nine known species of monogeneans, i. Read More

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https://www.parasite-journal.org/10.1051/parasite/2019003
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http://dx.doi.org/10.1051/parasite/2019003DOI Listing
February 2019
1 Read

International Perspectives on Old Age Psychiatry Training.

Am J Geriatr Psychiatry 2018 Dec 20. Epub 2018 Dec 20.

Department of Demographic Epidemiology and Social Determinants (AM), National Institute of Geriatrics, Mexico City, Mexico.

Psychiatry of old age is a psychiatric subspecialty that has been developed in many countries since the 1950s as an attempt to improve the care of older adults with mental health disorders. Psychiatry of old age specialist training programs were subsequently established to develop a medical workforce that has the required competencies to work in this subspecialty. This article describes the psychiatry of old age specialist training programs in Australia, New Zealand, the United Kingdom, and Mexico. Read More

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http://dx.doi.org/10.1016/j.jagp.2018.12.021DOI Listing
December 2018

Removal of antibiotics from aqueous solutions by nanoparticles: a systematic review and meta-analysis.

Environ Sci Pollut Res Int 2019 Jan 31. Epub 2019 Jan 31.

Environmental Health Engineering Research Center, Kerman University of Medical Sciences, Kerman, Iran.

Antibiotics, as one of the emerging pollutants, are non-biodegradable compounds and long-term exposure to them may affect endocrine, hormonal, and genetic systems of human beings, representing a potential risk for both the environment and human health. The presence of antibiotics in surface waters and drinking water causes a global health concern. Many researches have stated that conventional methods used for wastewater treatment cannot fully remove antibiotic residues, and they may be detected in receiving waters. Read More

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http://dx.doi.org/10.1007/s11356-019-04227-wDOI Listing
January 2019

New perspectives on Kawasaki disease.

Authors:
Jane C Burns

Arch Dis Child 2019 Jan 30. Epub 2019 Jan 30.

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http://dx.doi.org/10.1136/archdischild-2018-316322DOI Listing
January 2019
1 Read

Unmet health care needs in old age and their association with depression - results of a population-representative survey.

J Affect Disord 2019 02 19;245:998-1006. Epub 2018 Nov 19.

Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, Philipp-Rosenthal-Straße 55, Leipzig 04103, Germany.

Background: Due to the demographic changes, unmet health care needs are expected to increase in the elderly population. The aim of this study was to analyse the distribution of met and unmet needs and their association with depression in old age.

Methods: Based on a population-representative telephone survey of the elderly population aged 75 + years and older, a sample of 845 individuals was assessed via structured clinical interviews. Read More

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http://dx.doi.org/10.1016/j.jad.2018.11.096DOI Listing
February 2019

Consistency of child self-reports with parent proxy reports on the quality of life of children with attention-deficit/hyperactivity disorder in Riyadh, 2016.

J Family Community Med 2019 Jan-Apr;26(1):9-16

Department of Family and Community Medicine, College of Medicine and King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia.

Background: The quality of life (QoL) of children with attention-deficit/hyperactivity disorder (ADHD) has not been addressed in Saudi Arabia despite the considerable attention it has on account of its prevalence, duration of illness, and sociopsychological effects. The aim of this study was to report on the QoL of children with ADHD and test the concord between children's and parents' reports.

Materials And Methods: Using the generic PedsQL™ (version 4. Read More

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http://dx.doi.org/10.4103/jfcm.JFCM_19_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335840PMC
January 2019
1 Read

Perspectives of bereaved relatives of patients with haematological malignancies concerning preferred place of care and death: A qualitative study.

Palliat Med 2019 Jan 30:269216318824525. Epub 2019 Jan 30.

1 Epidemiology and Cancer Statistics Group, University of York, York, UK.

Background:: People with haematological malignancies have different end-of-life care patterns from those with other cancers and are more likely to die in hospital. Little is known about patient and relative preferences at this time and whether these are achieved.

Aim:: To explore the experiences and reflections of bereaved relatives of patients with leukaemia, lymphoma or myeloma, and examine (1) preferred place of care and death; (2) perceptions of factors influencing attainment of preferences; and (3) changes that could promote achievement of preferences. Read More

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http://dx.doi.org/10.1177/0269216318824525DOI Listing
January 2019

Prophylactic human papilloma virus vaccination in head and neck: indications and future perspectives.

Curr Opin Otolaryngol Head Neck Surg 2019 Jan 28. Epub 2019 Jan 28.

Department of Otorhinolaryngology, Amsterdam UMC, University of Amsterdam, Meibergdreef, Amsterdam, the Netherlands.

Purpose Of Review: To gain the evidence-based knowledge concerning the efficacy of HPV vaccination for oropharyngeal sites and to highlight the trials and strategies for vaccine administration in HPV-dependent head and neck diseases.

Recent Findings: Vaccination can be provided in two injections. There is increasing anecdotal evidence that therapeutic vaccination is effective in treatment of recurrent respiratory papillomatosis. Read More

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http://Insights.ovid.com/crossref?an=00020840-900000000-9921
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http://dx.doi.org/10.1097/MOO.0000000000000525DOI Listing
January 2019
8 Reads

New perspectives in Merkel cell carcinoma.

Curr Opin Oncol 2019 Mar;31(2):72-83

APHP, Department of Dermatology, Saint-Louis Hospital, Sorbonne Paris Cité Université, Paris Diderot, INSERM U976, Paris, France.

Purpose Of Review: Merkel cell carcinoma (MCC), a rapidly progressing skin cancer, has poor prognosis. We reviewed the epidemiology, pathogenesis, diagnosis and treatment of MCC, with a focus on recent therapeutic advancements.

Recent Findings: Risk factors for MCC, such as old age, immunosuppression, polyomavirus infection and exposure to UV radiation have already been identified, but the underlying mechanisms leading to carcinogenesis still need clarification. Read More

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http://Insights.ovid.com/crossref?an=00001622-900000000-9921
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http://dx.doi.org/10.1097/CCO.0000000000000508DOI Listing
March 2019
5 Reads

Mix methods approach to explore patients' perspectives on the acceptability of a urinary biomarker test in replacement of cystoscopy in bladder cancer surveillance.

BJU Int 2019 Jan 29. Epub 2019 Jan 29.

Division of Surgery and Interventional Science, University College London, London, UK.

Objective: To determine the minimal accepted sensitivity (MAS) of a urine biomarker that patients are willing to accept to replace cystoscopy and to qualitatively assess their views and reasons.

Patient And Methods: Patients were part of a prospective multi-center observational study recruiting patients with bladder cancer for a urine biomarker study (DETECT II; ClinicalTrials.gov: NCT02781428). Read More

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http://dx.doi.org/10.1111/bju.14690DOI Listing
January 2019
3.533 Impact Factor

Human T cell leukemia virus type 1 and Zika virus: tale of two reemerging viruses with neuropathological sequelae of public health concern.

J Neurovirol 2019 Jan 28. Epub 2019 Jan 28.

Department of Microbiology and Immunology, and the Institute for Molecular Medicine and Infectious Disease, Drexel University College of Medicine, 2900 West Queen Lane, Philadelphia, PA, 19102, USA.

Human T cell leukemia virus type 1 (HTLV-1) and Zika virus (ZIKV) have been considered neglected viruses of low public health concern until recently when incidences of HTLV-1 and ZIKV were observed to be linked to serious immune-related disease and neurological complications. This review will discuss the epidemiology, genomic evolution, virus-host interactions, virulence factors, neuropathological sequelae, and current perspectives of these reemerging viruses. There are no FDA-approved therapeutics or vaccines against these viruses, and as such, it is important for clinical trials to focus on developing vaccines that can induce cell-mediated immune response to confer long-term protective immunity. Read More

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http://link.springer.com/10.1007/s13365-019-00720-7
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http://dx.doi.org/10.1007/s13365-019-00720-7DOI Listing
January 2019
5 Reads

Transition Between Different Renal Replacement Modalities: Gaps in Knowledge and Care-The Integrated Research Initiative.

Perit Dial Int 2019 Jan-Feb;39(1):4-12

Ghent University Hospital, Ghent, Belgium

Patients with end-stage kidney disease (ESKD) have different options to replace the function of their failing kidneys. The "integrated care" model considers treatment pathways rather than individual renal replacement therapy (RRT) techniques. In such a paradigm, the optimal strategy to plan and enact transitions between the different modalities is very relevant, but so far, only limited data on transitions have been published. Read More

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http://dx.doi.org/10.3747/pdi.2017.00242DOI Listing
November 2017
2.199 Impact Factor

Academic Expectations and Mental Health in Adolescence: A Longitudinal Study Involving Parents' and Their Children's Perspectives.

J Adolesc Health 2019 Jan 25. Epub 2019 Jan 25.

Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden; Centre for Epidemiology and Community Medicine (CES), Stockholm County Council, Stockholm, Sweden.

Purpose: We investigated parental academic expectations and their agreement with child expectations as predictors of offspring's mental health. We additionally analyzed whether these associations were moderated by parent-child relationship factors and whether similar associations were found when using aspirations as the predictor.

Methods: Dyads of parents and children (aged 13 years) in Sweden answered three annual surveys asking how far in education parents (or their children) expected to go (respondents' wave 1: N = 3,383, wave 2: N = 3,096, wave 3: N = 2,905). Read More

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http://dx.doi.org/10.1016/j.jadohealth.2018.11.015DOI Listing
January 2019
2 Reads

Childhood socioeconomic circumstances and disability trajectories in older men and women: a European cohort study.

Eur J Public Health 2019 Feb;29(1):50-58

Institute of Demography and Socioeconomics, University of Geneva, Geneva, Switzerland.

Background: We observed a lack of population-based longitudinal research examining the association of disadvantaged childhood socioeconomic circumstances (CSC) and disability [activities of daily living (ADL) and instrumental activities of daily living (IADL)] in older age, and whether socioeconomic attainments in adulthood can compensate for a poor socioeconomic start in life.

Methods: Data on 24 440 persons aged 50-96 in 14 European countries (Survey of Health, Ageing and Retirement in Europe) were used to measure the associations between CSC and limitations with ADL and with IADL, using mixed-effects logistic regression models. Models stratified by gender were adjusted for education during young adulthood, main occupation during middle age, ability to make ends meet during old age and potential confounding and control variables. Read More

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http://dx.doi.org/10.1093/eurpub/cky166DOI Listing
February 2019

Sick leave assessments of workers with subjective health complaints: a cross-sectional study on differences among physicians working in occupational health care.

Disabil Rehabil 2019 Jan 26:1-8. Epub 2019 Jan 26.

a Department of Public and Occupational Health , Amsterdam Public Health research institute, VU University Medical Center , Amsterdam , The Netherlands.

Aims: To obtain more insight into differences in sick leave assessments of workers with subjective health complaints, we studied sick leave assessments among Dutch occupational and insurance physicians, and explored possible determinants for these differences.

Methods: A cross-sectional study was conducted among 50 occupational and 43 insurance physicians in the Netherlands. They all assessed sick leave (complete, partial or no) of nine video case vignettes of workers with subjective health complaints and gave their opinion on the complaints, sick leave and health status. Read More

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http://dx.doi.org/10.1080/09638288.2018.1513085DOI Listing
January 2019

Epidermolysis Bullosa Acquisita: The 2019 Update.

Front Med (Lausanne) 2018 10;5:362. Epub 2019 Jan 10.

Lübeck Institute of Experimental Dermatology, University of Lübeck, Lübeck, Germany.

Epidermolysis bullosa acquisita (EBA) is an orphan autoimmune disease. Patients with EBA suffer from chronic inflammation as well as blistering and scarring of the skin and mucous membranes. Current treatment options rely on non-specific immunosuppression, which in many cases, does not lead to a remission of treatment. Read More

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http://dx.doi.org/10.3389/fmed.2018.00362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335340PMC
January 2019
9 Reads

The impact and cost-effectiveness of combined HIV prevention scenarios among transgender women sex-workers in Lima, Peru: a mathematical modelling study.

Lancet Public Health 2019 Jan 22. Epub 2019 Jan 22.

Centro de Investigación Interdisciplinaria en Sexualidad, SIDA y Sociedad, Universidad Cayetano Heredia, Lima, Peru.

Background: HIV incidence remains high among transgender women in Lima, Peru, most of whom report sex work. On the basis of a stakeholder analysis and health system capacity assessment, we designed a mathematical model to guide HIV programmatic planning among transgender women sex workers (TWSW) in Lima.

Methods: Using a deterministic compartmental model, we modelled HIV transmission among TWSW, their stable partners, and their clients to estimate the impact and cost-effectiveness of combinations of interventions compared with the standard of care on reducing HIV incidence over a 10-year period. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24682667183023
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http://dx.doi.org/10.1016/S2468-2667(18)30236-6DOI Listing
January 2019
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Hearing Norton Sound: mixed methods protocol of a community randomised trial to address childhood hearing loss in rural Alaska.

BMJ Open 2019 Jan 22;9(1):e023081. Epub 2019 Jan 22.

Norton Sound Health Corporation, Nome, Alaska, USA.

Introduction: Childhood hearing loss has implications for school achievement, economic outcomes and quality of life. This study will engage rural Alaska communities in research to improve the school hearing screening and referral process, partnering with stakeholders to develop a locally derived, evidence-based solution to improve timely identification and treatment of childhood hearing loss.

Methods And Analysis: Mixed methods community randomised trial in 15 communities in the Norton Sound region of northwest Alaska. Read More

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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2018-02308
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http://dx.doi.org/10.1136/bmjopen-2018-023081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347925PMC
January 2019
4 Reads

Coital Frequency and Male Concurrent Partnerships During Pregnancy and Postpartum in Agbogbloshie, Ghana.

AIDS Behav 2019 Jan 23. Epub 2019 Jan 23.

Regional Institute for Population Studies, University of Ghana, Legon, Ghana.

During pregnancy and postpartum, women in high HIV prevalence regions continue to be at high risk for acquiring HIV, due to both behavioral and biological mechanisms, despite declines in coital frequency as a pregnancy advances. We estimated differences in rates of partnership concurrency for men with and without pregnant or postpartum sexual partners. We used monthly retrospective panel data from Ghana from three perspectives: couple-level data, female reports of pregnancy and male partner concurrency, and male reports of concurrent partnerships and female partner pregnancy. Read More

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http://dx.doi.org/10.1007/s10461-019-02403-0DOI Listing
January 2019

Current status, problems, and perspectives of non-alcoholic fatty liver disease research.

World J Gastroenterol 2019 Jan;25(2):163-177

Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto 390-8621, Japan.

Non-alcoholic fatty liver disease (NAFLD) is a major chronic liver disease that can lead to liver cirrhosis, liver cancer, and ultimately death. NAFLD is pathologically classified as non-alcoholic fatty liver (NAFL) or non-alcoholic steatohepatitis (NASH) based on the existence of ballooned hepatocytes, although the states have been known to transform into each other. Moreover, since the detection of ballooned hepatocytes may be difficult with limited biopsied specimens, its clinical significance needs reconsideration. Read More

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http://dx.doi.org/10.3748/wjg.v25.i2.163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337019PMC
January 2019
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Safe and effective person- and family-centered care practices during transitions from hospital to home-A web-based Delphi technique.

PLoS One 2019 22;14(1):e0211024. Epub 2019 Jan 22.

Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Canada.

Background: Research has shown that adverse events during care transitions from hospital to home can have a significant impact on patients' outcomes, leading to readmission, delayed healing or even death. Gaps exist in the ways of monitoring care during transition periods and there is a need to help organizations better implement and monitor safe person-and family-centered care. Value statements are a way to obtain narratives in lay terms about how well care, treatment and support is organized to meet the needs and preferences of patients/families. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0211024PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342305PMC
January 2019

Adapting the Interpersonal Quality in Family Planning care scale to assess patient perspectives on abortion care.

J Patient Rep Outcomes 2019 Jan 21;3(1). Epub 2019 Jan 21.

Sydney School of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, 2006, NSW, Australia.

Background: Women value receiving quality interpersonal care during abortion services, yet no measure exists to assess this outcome from patients' perspectives. We sought to adapt the Interpersonal Quality in Family Planning care scale (Dehlendorf et al., American Journal of Obstetrics Gynaecology 10. Read More

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http://dx.doi.org/10.1186/s41687-018-0089-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340910PMC
January 2019

Healthcare professionals' perspectives on working conditions, leadership, and safety climate: a cross-sectional study.

BMC Health Serv Res 2019 Jan 21;19(1):53. Epub 2019 Jan 21.

Institute for Patient Safety, University Hospital of Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany.

Background: Promoting patient and occupational safety are two key challenges for hospitals. When aiming to improve these two outcomes synergistically, psychosocial working conditions, leadership by hospital management and supervisors, and perceptions of patient and occupational safety climate have to be considered. Recent studies have shown that these key topics are interrelated and form a critical foundation for promoting patient and occupational safety in hospitals. Read More

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http://dx.doi.org/10.1186/s12913-018-3862-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341698PMC
January 2019

Barriers and facilitators of pediatric shared decision-making: a systematic review.

Implement Sci 2019 Jan 18;14(1). Epub 2019 Jan 18.

Faculty of Health Sciences, University of Ottawa, 540 King Edward Avenue, Ottawa, ON, K1N 6N5, Canada.

Background: Shared decision-making (SDM) is rarely implemented in pediatric practice. Pediatric health decision-making differs from that of adult practice. Yet, little is known about the factors that influence the implementation of pediatric shared decision-making (SDM). Read More

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http://dx.doi.org/10.1186/s13012-018-0851-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339273PMC
January 2019
1 Read