8,832 results match your criteria Ephelides Freckles


Neurocutaneous Melanosis in Association With Large Congenital Melanocytic Nevi in Children: A Report of 2 Cases With Clinical, Radiological, and Pathogenetic Evaluation.

Front Neurol 2019 7;10:79. Epub 2019 Feb 7.

Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan.

Melanocytic nevi present at birth, or within the first few months of life, are defined as congenital melanocytic nevi (CMN). Neurocutaneous melanosis (NCM) is a rare disorder, represents pigment cell tumors of the leptomeninges, and occurs in association with large or multiple CMN. NCM carries an extremely poor prognosis. Read More

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http://dx.doi.org/10.3389/fneur.2019.00079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374324PMC
February 2019

Melanoma arising in a Giant congenital melanocytic nevus: two case reports.

Diagn Pathol 2019 Feb 19;14(1):21. Epub 2019 Feb 19.

Federal State Budgetary Institution, "N.N. Blokhin Medical Research Center of Oncology" of the Ministry of Health of the Russian Federation, 115478 Kashirskoye shosse, 24, Moscow, Russian Federation.

Background: A giant congenital melanocytic nevus (GCMN) is found in 0.1% of live-born infants. If present, the lesion has a chance of about 6% to develop into malignant melanoma. Read More

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http://dx.doi.org/10.1186/s13000-019-0797-1DOI Listing
February 2019

Ocular Surface Squamous Neoplasia Hiding in Primary Acquired Melanosis.

JAMA Ophthalmol 2019 Feb 14. Epub 2019 Feb 14.

Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami, Miami, Florida.

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http://archopht.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaophthalmol.2018.6503DOI Listing
February 2019
3 Reads

Gastric Tumoral Melanosis: a Rare Manifestation of Successfully Treated Malignant Melanoma.

Clin Gastroenterol Hepatol 2019 Feb 8. Epub 2019 Feb 8.

Department of General Medical Oncology, University Hospitals Leuven, KU Leuven, Belgium.

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http://dx.doi.org/10.1016/j.cgh.2019.02.006DOI Listing
February 2019
1 Read

Peutz-Jeghers Syndrome.

N Engl J Med 2019 Jan;380(5):472

R.G. Kar Medical College and Hospital, Kolkata, India

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http://dx.doi.org/10.1056/NEJMicm1806623DOI Listing
January 2019
1 Read

Black and Brown Oro-facial Mucocutaneous Neoplasms.

Authors:
Easwar Natarajan

Head Neck Pathol 2019 Jan 29. Epub 2019 Jan 29.

Section of Oral and Maxillofacial Pathology, University of Connecticut Health Center, 263 Farmington Ave, MC-0925, Farmington, CT, 06030, USA.

Black and brown-colored mucocutaneous lesions present a differential diagnostic challenge, with malignant melanoma being the primary clinical concern. The vast majority of pigmented lesions in the head and neck region are the result of benign, reactive factors such as post-inflammatory melanosis. However, it is not uncommon to discover a range of muco-cutaneous black and brown neoplasms in the oro-facial area. Read More

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http://dx.doi.org/10.1007/s12105-019-01008-2DOI Listing
January 2019
2 Reads

Black and Brown: Non-neoplastic Pigmentation of the Oral Mucosa.

Head Neck Pathol 2019 Jan 22. Epub 2019 Jan 22.

Louisiana State University, 1100 Florida Avenue, New Orleans, LA, 70119, USA.

Black and brown pigmentation of the oral mucosa can occur due to a multitude of non-neoplastic causes. Endogenous or exogenous pigments may be responsible for oral discoloration which can range from innocuous to life-threatening in nature. Physiologic, reactive, and idiopathic melanin production seen in smoker's melanosis, drug-related discolorations, melanotic macule, melanoacanthoma and systemic diseases are presented. Read More

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http://dx.doi.org/10.1007/s12105-018-0980-9DOI Listing
January 2019
3 Reads

Common Neonatal Rashes.

Pediatr Ann 2019 Jan;48(1):e16-e22

Skin eruptions are commonly encountered in the neonatal and infant period and can be a source of concern for providers and parents alike. We present a brief, clinically focused discussion on topics commonly encountered by the pediatrician with a focus on pearls of knowledge to help distinguish diseases from one another and from more serious conditions. We review miliaria, transient neonatal pustular melanosis, neonatal cephalic pustulosis, erythema toxicum neonatorum, diaper dermatitis, seborrheic dermatitis, and atopic dermatitis. Read More

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http://dx.doi.org/10.3928/19382359-20181206-01DOI Listing
January 2019
4 Reads

[Diagnosis and treatment for 46 cases of Peutz-Jeghers syndrome].

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2018 Dec;43(12):1323-1327

Department of Gastroenterology, the Seventh Medical Center of PLA General Hospital, Beijing 100700, China.

Objective: To explore the clinical features, pathological features, gene test results, diagnosis, treatment and prognosis of Peutz-Jeghers syndrome(PJS).
 Methods: We retrospectively analyzed clinical data of 46 hospitalized cases of PJS during 2007 and 2017.
 Results: All 46 patients had mucocutaneous melanin pigmentation and multiple gastrointestinal polyposis. Read More

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http://www.csumed.org/xbwk/CN/10.11817/j.issn.1672-7347.2018
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http://dx.doi.org/10.11817/j.issn.1672-7347.2018.12.007DOI Listing
December 2018
4 Reads

Melanosis Coli: A Case of Mistaken Identity-A Case Report.

Perm J 2019 ;23

Division of Acute Care Surgery and Trauma, Memorial Regional Hospital, Hollywood, FL.

Introduction: Melanosis coli is a condition in which the colon develops a brown to black discoloration. It is associated with chronic laxative use and frequently diagnosed incidentally during colonoscopy or histopathologic evaluation.

Case Presentation: A 74-year-old woman presented to the Emergency Department with severe abdominal pain and bilious emesis. Read More

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http://dx.doi.org/10.7812/TPP/18-063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326559PMC
January 2019
1 Read

Photo-Modification of Melanin by a Mid-infrared Free-electron Laser.

Photochem Photobiol 2019 Jan 5. Epub 2019 Jan 5.

Institute of Advanced Energy, Kyoto University, Gokasho, Uji, Kyoto, Japan.

Melanin is rigidly constructed by several nitrogen-containing aromatic rings, and its excess accumulation in skin tissue is closely associated with melanosis. Although visible lasers (wavelength: 600-1000 nm) are conventionally used for the photo-thermolysis of melanocyte, several pigmented nevi are difficult to be treated. Here, we propose an alternate method for targeting the molecular structure of melanin using an infrared free-electron laser (FEL) tuned to 5. Read More

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http://dx.doi.org/10.1111/php.13079DOI Listing
January 2019
1 Read

Comparison of the Inflammatory Infiltrates in Tumoral Melanosis, Regressing Nevi, and Regressing Melanoma.

Am J Dermatopathol 2018 Dec 19. Epub 2018 Dec 19.

Department of Dermatology, University of Florida College of Medicine, Gainesville, FL.

Background: Tumoral melanosis (TM) is a histologic diagnosis characterized by abundant pigment-laden macrophages in the dermis. It is generally thought to represent a regressed melanoma, although it has also been reported after benign pigmented lesions as well. Determining the antecedent lesion in cases of TM is of clinical importance to accurately guide therapy and prognostication. Read More

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http://dx.doi.org/10.1097/DAD.0000000000001346DOI Listing
December 2018
4 Reads

Pseudomelanosis intestini "from pylorus to jejunum:" A rare endoscopic finding in a patient with GI bleeding.

J Family Med Prim Care 2018 Sep-Oct;7(5):1120-1122

Department of Gastroenterology, Providence-Providence Park Hospital, Michigan State University College of Human Medicine, Southfield, Michigan, USA.

Pseudomelanosis of the gastrointestinal (GI) tract is a rare condition used to describe the accumulation of pigment deposits in the intestinal mucosa. Its underlying cause is not well understood. It has been described in association with gastrointestinal hemorrhage, chronic kidney disease, hypertension, diabetes mellitus, and medications such as hydralazine, ferrous sulfate, and furosemide. Read More

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http://dx.doi.org/10.4103/jfmpc.jfmpc_53_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259497PMC
January 2019

[Friction melanosis and mode of dress].

Pan Afr Med J 2018 17;30:215. Epub 2018 Jul 17.

Service de Dermatologie-Vénérologie, Hôpital d'Instruction Mohammed V, Rabat, Maroc.

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http://www.panafrican-med-journal.com/content/article/30/215
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http://dx.doi.org/10.11604/pamj.2018.30.215.16239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294982PMC
January 2019
1 Read

Melanosis Coli: A Helpful Contrast Effect or a Harmful Pigmentation?

Clin Med Insights Gastroenterol 2018 4;11:1179552218817321. Epub 2018 Dec 4.

Department of Gastroenterology and Hepatology, Hillel Yaffe Medical Center, Technion Faculty of Medicine, Hadera, Israel.

Background: Melanosis coli, a brown discoloration of colonic mucosa, is considered as a benign condition mainly observed in patients under chronic anthranoid laxatives. Recent data link this condition with an increased adenoma detection rate. Moreover, its tumorigenic potential and possible association with the development of colorectal cancer remains uncertain. Read More

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http://dx.doi.org/10.1177/1179552218817321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299301PMC
December 2018
6 Reads

Corneal dysplastic melanosis associated with recurrent corneal erosions: A case report.

Medicine (Baltimore) 2018 Dec;97(51):e13367

Department of Ophthalmology, Seoul National University College of Medicine.

Rationale: Pigmented lesions of conjunctiva and cornea can be observed in various conditions, from the benign nevus to malignant melanoma. Pigmented acquired melanosis (PAM) is one of them, which is a neoplastic proliferation with malignant transformation potential of melanocytes. However, to our knowledge, there has been no report as to a disturbance of corneal barrier function caused by PAM. Read More

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http://dx.doi.org/10.1097/MD.0000000000013367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319972PMC
December 2018
8 Reads

Identification of candidate biomarkers associated with apoptosis in melanosis coli: GNG5, LPAR3, MAPK8, and PSMC6.

Biosci Rep 2019 Jan 18;39(1). Epub 2019 Jan 18.

Clinical Laboratory, Hangzhou Cancer Hospital, Hangzhou 310000, Zhejiang, China

Melanosis coli (MC) is a disorder of pigmentation of the wall of the colon, often identified at the time of colonoscopy. The aim of the present study is to identify candidate biomarkers for MC. The transcriptome data for MC (GSE78933) with five MC tissues and five corresponding normal tissues is obtained from the NCBI Gene Expression Omnibus (GEO) database. Read More

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http://dx.doi.org/10.1042/BSR20181369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340944PMC
January 2019

Effects of moringa leaves () extraction on quality changes and melanosis of giant freshwater prawn () during chilled storage.

Ital J Food Saf 2018 Sep 26;7(3):6846. Epub 2018 Sep 26.

Institute of Tropical Aquaculture.

An aqueous extraction of moringa () leaves were prepared as the edible coats for keeping the quality of the giant freshwater prawn (). In addition, the antioxidant properties and activity; total phenolic content (TPC), total flavonoid contents (TFC), free radical scavenging activity (DPPH), and ferric reducing antioxidant power (FRAP) of moringa leaves were also determined. The phenolic compounds and antioxidant properties in the moringa leaves are low; 16. Read More

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http://dx.doi.org/10.4081/ijfs.2018.6846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240840PMC
September 2018
1 Read

Acquired diffuse slate-grey facial dyspigmentation due to henna: an unrecognized cause of pigment contact dermatitis in Korean patients.

Eur J Dermatol 2018 Oct;28(5):644-648

Department of Dermatology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Henna is a vegetable hair dye that can be used by individuals who are sensitized to oxidative dyes due to low allergenicity. The reported incidence of slate-grey facial dyspigmentation following the use of henna hair dye is extremely rare. This study aimed to identify the clinical, dermoscopic, and histopathological features of slate-grey facial dyspigmentation following the use of henna hair dye in Korean patients. Read More

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http://dx.doi.org/10.1684/ejd.2018.3404DOI Listing
October 2018
15 Reads

Bilateral Iris Mammillations in Amblyopic Eyes without Oculodermal Melanocytosis or Neurofibromatosis.

Case Rep Ophthalmol Med 2018 29;2018:2534042. Epub 2018 Oct 29.

Department of Ophthalmology, Teikyo University School of Medicine, Tokyo 173-8605, Japan.

Purpose: Iris mammillations are related to oculodermal melanosis and iris nevi. We report a rare case of bilateral simple iris mammillations without ocular melanosis or systemic neuronal disorders.

Case Report: A healthy 10-year-old Japanese girl was found incidentally to have bilateral iris mammillations while being treated for amblyopia. Read More

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http://dx.doi.org/10.1155/2018/2534042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231380PMC
October 2018
2 Reads

Clinicopathologically problematic melanocytic tumors: a case-based review.

Dermatol Pract Concept 2018 Oct 31;8(4):306-313. Epub 2018 Oct 31.

Anatomic Pathology Unit, Hospital of Macerata, Italy.

Background: In spite of recent advances in the histopathological and molecular diagnosis of melanocytic neoplasms, a certain proportion of these lesions remain a daunting challenge for both the clinician and the pathologist.

Objectives: To emphasize the importance of close collaboration between clinicians and pathologists in case of problematic melanocytic lesions.

Patients: We report and discuss 5 problematic scenarios of melanocytic lesions, including tumoral melanosis, nevoid melanoma, lentiginous melanoma, spitzoid melanoma and BAPoma that may pose diagnostic difficulties in our practice. Read More

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http://dx.doi.org/10.5826/dpc.0804a12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246059PMC
October 2018
1 Read

Going Viral 2019: Zika, Chikungunya, and Dengue.

Dermatol Clin 2019 Jan;37(1):95-105

Department of Dermatology, University Hospital "Dr. José E. González", Universidad Autónoma de Nuevo León, Mitras Centro, Avenida Gonzalitos y Madero S/N, Monterrey 64460, Mexico.

Chikungunya and Zika virus infections are emerging diseases in the Americas, and dengue continues to be the most prevalent arthropod-borne virus in the world. These arbovirus diseases may spread by endemic transmission or as travel-related infections and have rapidly expanded their geographic distribution secondary to vector spread. All 3 share a similar clinical picture that includes a maculopapular rash. Read More

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http://dx.doi.org/10.1016/j.det.2018.07.008DOI Listing
January 2019
21 Reads

A melanosis coli associated with a large flat adenoma of the cecum.

Clin Res Hepatol Gastroenterol 2018 Nov 14. Epub 2018 Nov 14.

Department of pathology, university hospital, 37044 Tours cedex 9, France.

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http://dx.doi.org/10.1016/j.clinre.2018.10.006DOI Listing
November 2018

Neurocutaneous Melanosis with Leptomeningeal Melanoma Involving Supratentorium and Infratentorium.

Cureus 2018 Sep 10;10(9):e3275. Epub 2018 Sep 10.

Radiotherapy, Christian Medical College, Vellore, IND.

Neurocutaneous melanoma is a rare congenital syndrome associated with congenital melanocytic nevi with meningeal melanosis or melanoma. The disease is aggressive and has a high propensity for leptomeningeal metastases. We present the case history of a man with neurocutaneous melanoma managed with radical excision followed by hypofractionated adjuvant radiotherapy. Read More

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http://dx.doi.org/10.7759/cureus.3275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235644PMC
September 2018
4 Reads

Evaluation of the Prevalence of Oral Mucosal Lesions in a Population of Eastern Coast of South India.

J Int Soc Prev Community Dent 2018 Sep-Oct;8(5):396-401. Epub 2018 Oct 8.

Department of Public Health Dentistry, Sibar Institute of Dental Sciences and Research, Guntur, Andhra Pradesh, India.

Objective/aim: The aim of this study is to measure the association between oral mucosal lesions (OMLs) and habit of tobacco and alcohol in the population of Guntur city, Andhra Pradesh, South India.

Material And Method: A cross-sectional study was conducted on 300 participants in Guntur city with the habit of tobacco and alcohol consumption in various forms who were selected by stratified cluster random sampling technique. Guntur city was divided into four zones, that is, North, East, South, and West; and two administrative wards were randomly selected from each zone as clusters. Read More

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http://www.jispcd.org/text.asp?2018/8/5/396/242866
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http://dx.doi.org/10.4103/jispcd.JISPCD_207_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187880PMC
October 2018
3 Reads

Extensive Vulvar Melanosis.

Actas Dermosifiliogr 2018 Oct 31. Epub 2018 Oct 31.

Departamento de Dermatología, Hospital Costa del Sol, Marbella, Málaga, España.

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http://dx.doi.org/10.1016/j.ad.2017.07.027DOI Listing
October 2018
2 Reads

Diffuse palmoplantar keratotic papules and melanosis.

Int J Dermatol 2019 Jan 21;58(1):e9-e10. Epub 2018 Oct 21.

Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1111/ijd.14265DOI Listing
January 2019
2 Reads

A pilot study of oral tranexamic acid and Glycyrrhizin compound in the treatment of recalcitrant Riehl's melanosis.

J Cosmet Dermatol 2019 Feb 19;18(1):286-292. Epub 2018 Oct 19.

Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.

Background: Up till now, there is no standardized and satisfactory treatment strategy for Riehl's melanosis.

Objective: In this pilot study, we evaluated the efficacy and safety of a novel combination therapy with oral administration of tranexamic acid (TA) and Glycyrrhizin compound for recalcitrant Riehl's melanosis.

Methods: Ten patients with Riehl's melanosis were recruited in this study. Read More

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http://dx.doi.org/10.1111/jocd.12797DOI Listing
February 2019
4 Reads

Tumoral melanosis associated with combined / inhibition (dabrafenib/trametinib) in metastatic melanoma.

JAAD Case Rep 2018 Oct 10;4(9):921-923. Epub 2018 Oct 10.

Dermatology Research Centre, The University of Queensland, The University of Queensland Diamantina Institute, Brisbane, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S23525126183017
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http://dx.doi.org/10.1016/j.jdcr.2018.06.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180233PMC
October 2018
1 Read

A dermatoscopic portrait of morphological changes of vulvar melanosis over time.

J Dtsch Dermatol Ges 2018 Nov 9;16(11):1372-1375. Epub 2018 Oct 9.

Unit of Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, Policlinico Sant'Orsola-Malpighi, University of Bologna, Italy.

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http://doi.wiley.com/10.1111/ddg.13672
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http://dx.doi.org/10.1111/ddg.13672DOI Listing
November 2018
2 Reads
1.820 Impact Factor

Neurocutaneous Melanosis with Bilateral Temporal Lobe Lesions without Leptomeningeal Enhancement: A Distinct Entity or Subtype.

J Pediatr Neurosci 2018 Jul-Sep;13(3):331-333

Department of Radiology, Command Hospital (Central Command), Lucknow Cantonment, Lucknow, Uttar Pradesh, India.

Neurocutaneous melanosis (NCM) is a rare congenital disorder. Most of the cases described in literature for this entity have involvement of the leptomeninges and other structures of brain such as brain stem, temporal lobes, and spinal meninges and no involvement of leptomeninges and presence of lesions in bilateral temporal lobes. NCM without the involvement of leptomeninges should be considered a distinct entity as the prognosis is favorable as compared to cases with leptomeningeal involvement who develop early hydrocephalus and multiple cranial nerve palsies. Read More

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http://dx.doi.org/10.4103/JPN.JPN_53_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144608PMC
October 2018
3 Reads

[Primary melanoma of the bladder. A case report].

Rev Esp Patol 2018 Oct - Dec;51(4):244-247. Epub 2018 Feb 23.

Departamento de Patología, Hospital General San Juan de Dios, Guatemala, Guatemala.

Primary melanoma of the urinary bladder is rare. We report a case of a 58-year-old woman, who presented with a 4 month history of dysuria and hematuria. A biopsy indicated a diagnosis of invasive melanoma and a partial cystectomy was performed. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S16998855183000
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http://dx.doi.org/10.1016/j.patol.2017.12.001DOI Listing
February 2018
2 Reads

Effect of layer-by-layer antimicrobial edible coating of alginate and chitosan with grapefruit seed extract for shelf-life extension of shrimp (Litopenaeus vannamei) stored at 4 °C.

Int J Biol Macromol 2018 Dec 26;120(Pt B):1468-1473. Epub 2018 Sep 26.

Department of Food and Nutrition, Kookmin University, Seoul 136-702, Republic of Korea. Electronic address:

The effect of a layer-by-layer (LbL) electrostatic deposition coating of alginate and chitosan with grapefruit seed extract was investigated on the shelf life of shrimp (Litopenaeus vannamei) stored for 15 days under refrigeration (4 °C). The shrimp were periodically analyzed for changes in microbiological parameters (total aerobic mesophilic bacteria and total aerobic psychrotrophic bacteria counts), chemical parameters, melanosis, and sensory characteristics. The chitosan-alginate coating had the advantage of reducing the bacterial count by 2 log CFU in combination with the antimicrobial activity of the grapefruit seed extract. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2018.09.160DOI Listing
December 2018

[Peutz-Jegher syndrome presenting with intussusception].

Laeknabladid 2018 Oktober;104(10):439-441

Surgical unit at Landspítali, University Hospital, Iceland.

In this case report we describe a patient with a confirmed diagnosis of Peutz-Jegher syndrome. A diagnosis made from a positive tissue sample from the small bowels and characteristic hyperpigmentation on the patient's lips. This particular patient wasn't diagnosed till he got intussusception which required an operation. Read More

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http://dx.doi.org/10.17992/lbl.2018.10.200DOI Listing
January 2019
1 Read

Approach to Skin Lightening in Patients With Melasma.

Authors:
Philip R Cohen

J Drugs Dermatol 2018 Sep;17(9):1018

I read with interest the informative article by Spencer et al1 that describes the efficacious use as a novel skin lightening agent (LumaPro-C) for the treatment of patients with melasma. Read More

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September 2018
3 Reads

A Randomized, Double-Blind, Placebo-Controlled, Split-Face Study of the Efficacy of Topical Epidermal Growth Factor for the Treatment of Melasma.

J Drugs Dermatol 2018 Sep;17(9):970-973

Introduction: Melasma is a condition in which patients develop symmetric, reticulated, hyperpigmented macules and patches on the face which is thought to be the result of ultraviolet (UV) exposure and hormonal influences, although the pathogenesis is not completely understood. The topical application of epidermal growth factor has been used as a whitening agent, moisturizer, and an aid for wound healing. In this study, we explore the efficacy of topical EGF in the treatment of melasma. Read More

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September 2018
34 Reads

The Management of Melasma on Skin Types V and VI Using Light Emitting Diode Treatment.

Photomed Laser Surg 2018 Oct 18;36(10):522-529. Epub 2018 Sep 18.

2 Faculty of Health Sciences, Laser Research Centre, University of Johannesburg , Doornfontein, South Africa .

Objective: This study investigated light emitting diode (LED) treatment for patients with melasma on darker skin types.

Background: Melasma is a common disfiguring skin condition in women which is difficult to treat and is refractory. The cause of melasma remains unclear. Read More

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https://www.liebertpub.com/doi/10.1089/pho.2018.4486
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http://dx.doi.org/10.1089/pho.2018.4486DOI Listing
October 2018
14 Reads

Unilateral retinoblastoma with contralateral isolated choroidal Melanocytosis: case report of an unexpected presentation.

BMC Ophthalmol 2018 Sep 17;18(1):251. Epub 2018 Sep 17.

Department of Ophthalmology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Background: Congenital ocular melanocytosis has been shown to be extremely uncommon in studies of numerous infants and children with retinoblastoma and disorders such as retinopathy of prematurity.

Case Presentation: A 33-month-old Caucasian boy presented with a solid white predominantly endophytic retinoblastoma filling most of the nasal aspect of the fundus and extensive vitreous seeding. Fundus exam of the contralateral eye showed a broad-based flat melanotic area of the choroid extending from the subfoveal region to the ora serrata temporally. Read More

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http://dx.doi.org/10.1186/s12886-018-0916-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142679PMC
September 2018
2 Reads

The Largest Mass Poisoning in History: Arsenic Contamination of Well Water in Bangladesh.

Skinmed 2018 1;16(4):265-267. Epub 2018 Jul 1.

From the Department of Dermatology, SUNY Downstate Medical Center at Brooklyn, Brooklyn, New York, NY.

Arsenic is a naturally occurring compound that is widely distributed in trace quantities in the environment. Levels toxic to humans have been found contaminating certain regions of the world and their groundwater, leading to deleterious effects. In fact, an estimated 150 million people are affected by arsenic contamination worldwide. Read More

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July 2018
1 Read

Shunt Surgery for Neurocutaneous Melanosis with Hydrocephalus: Case Report and Review of the Literature.

World Neurosurg 2018 Dec 8;120:583-589.e3. Epub 2018 Sep 8.

Section of Neurosurgery, Department of Neurosciences, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Philippines. Electronic address:

Background: Neurocutaneous melanosis is a rare phakomatosis characterized by large or multiple pigmented nevi and melanosis of the leptomeninges. It is often complicated by hydrocephalus due to melanotic deposits interfering with cerebrospinal fluid reabsorption in the basal cisterns or causing foraminal or aqueductal obstruction. In 10% of cases, it will be associated with the Dandy-Walker complex. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.09.002DOI Listing
December 2018
9 Reads

Tumoral Melanosis Arising on a Mycosis Fungoides Plaque

Balkan Med J 2018 11 11;35(6):447-448. Epub 2018 Sep 11.

Department of Pathology, Ankara University School of Medicine, Ankara, Turkey

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http://dx.doi.org/10.4274/balkanmedj.2018.0936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251375PMC
November 2018
7 Reads

Dermoscopy of Pigmentary Disorders in Brown Skin.

Dermatol Clin 2018 Oct;36(4):473-485

Department of Dermatology, Command Hospital, 17/1E, Alipore Road, Alipore Police Line, Alipore, Kolkata, West Bengal 700027, India. Electronic address:

Dermoscopy is a noninvasive technique for the diagnosis, prognosis, and monitoring of pigmentary disorders in brown skin. It can be used for the diagnosis of various facial melanoses, which can avoid the need for biopsy in many cases. It can also help in early identification of the adverse effect of topical steroids and hydroquinone when they are used for the treatment of these disorders. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07338635183108
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http://dx.doi.org/10.1016/j.det.2018.05.014DOI Listing
October 2018
15 Reads
1.434 Impact Factor

Dermoscopy for the Diagnosis of Conjunctival Lesions.

Dermatol Clin 2018 Oct 16;36(4):439-449. Epub 2018 Aug 16.

Department of Medical, Surgical and Neurological Science, Dermatology Section, University of Siena, S. Maria Alle Scotte Hospital, Viale Bracci 16, Siena 53100, Italy.

This article describes the present literature on dermoscopy of conjunctiva and shows the results of a dermoscopy study of 147 conjunctival tumors. Melanomas were characterized by a heavy pigmentation, irregular dots, and a higher prevalence of gray color compared with nevi. Squamous cell carcinomas had peculiar hairpin and glomerular vessels. Read More

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http://dx.doi.org/10.1016/j.det.2018.05.011DOI Listing
October 2018
25 Reads

A global consensus statement on ashy dermatosis, erythema dyschromicum perstans, lichen planus pigmentosus, idiopathic eruptive macular pigmentation, and Riehl's melanosis.

Int J Dermatol 2019 Mar 3;58(3):263-272. Epub 2018 Sep 3.

Department of Dermatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Ashy dermatosis (AD), lichen planus pigmentosus (LPP), erythema dyschromicum perstans (EDP), and idiopathic eruptive macular pigmentation are several acquired macular hyperpigmentation disorders of uncertain etiology described in literature. Most of the published studies on these disorders are not exactly comparable, as there are no clear definitions and different regions in the world describe similar conditions under different names. A consensus on the terminology of various morphologies of acquired macular pigmentation of uncertain etiology was a long-felt need. Read More

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http://dx.doi.org/10.1111/ijd.14189DOI Listing
March 2019
20 Reads
1.230 Impact Factor

Effect of Chamuang (Garcinia cowaRoxb.) leaf extract on inhibition of melanosis and quality changes of Pacific white shrimp during refrigerated storage.

Food Chem 2019 Jan 21;270:554-561. Epub 2018 Jul 21.

Department of Food Technology, Faculty of Agro-Industry, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand.

Inhibition of Pacific white shrimp polyphenoloxidase (PPO) with Chamuang leaf extract (CLE) was studied. CLE was rich in polyphenolic glycosides, in which chrysoeriol 6-C-glucoside-8-C-arabinopyranoside and 2-feruloyl-l-sinapoylgentiobiose were dominant. It also contained organic acids including hydroxycitric acid and oxalosuccinic acid. Read More

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http://dx.doi.org/10.1016/j.foodchem.2018.07.139DOI Listing
January 2019
2 Reads
3.391 Impact Factor

Familial acanthosis nigricans with the FGFR3 mutation: Differences of pigmentation between male and female patients.

J Dermatol 2018 Nov 31;45(11):1357-1361. Epub 2018 Aug 31.

Department of Dermatology, Gunma University Graduate School of Medicine, Maebashi, Japan.

Familial acanthosis nigricans caused by the mutation of the fibroblast growth factor receptor 3 (FGFR3) gene is characterized by short stature, hypochondroplasia and acanthosis nigricans. We herein report a Japanese family that showed a missense mutation of c.1948A>C (p. Read More

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http://dx.doi.org/10.1111/1346-8138.14623DOI Listing
November 2018
13 Reads

Widespread keratosis pilaris in a patient with Noonan syndrome with multiple lentigines.

Int J Dermatol 2018 11 27;57(11):e140-e141. Epub 2018 Aug 27.

Department of Dermatology, University of Health Sciences, Ankara Numune Training and Research Hospital, Ankara, Turkey.

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http://doi.wiley.com/10.1111/ijd.14209
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http://dx.doi.org/10.1111/ijd.14209DOI Listing
November 2018
5 Reads

NRAS mutated diffuse leptomeningeal melanomatosis in an adult patient with a brief review of the so-called "forme fruste" of neurocutaneous melanosis.

Brain Tumor Pathol 2018 Oct 25;35(4):217-223. Epub 2018 Aug 25.

Pathology Unit, Department of Pathology and Diagnostics, University and Hospital Trust of Verona, Verona, Italy.

Primary melanocytic tumors of central nervous system represent rare tumors arising from melanocytes of the leptomeninges. These neoplasms include focal forms like melanocytoma and primary malignant melanoma and diffuse forms like leptomeningeal melanocytosis and primary leptomeningeal melanomatosis. The clinical diagnosis remains challenging, with clinical and radiologic features overlapping with other more common diseases. Read More

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http://link.springer.com/10.1007/s10014-018-0328-x
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http://dx.doi.org/10.1007/s10014-018-0328-xDOI Listing
October 2018
11 Reads