393 results match your criteria Eosinophilic Ulcer

Atypical presentation at acute gastritis: significant gastric wall thickening as a presentation of a primary infection in children.

BMJ Case Rep 2021 Jul 9;14(7). Epub 2021 Jul 9.

Pediatric Surgery, Kanazawa Medical University, Kahoku-gun, Ishikawa, Japan.

infection could cause chronic inflammation in the stomach and induce peptic ulcer disease or even malignant tumour. The initial infection of the organism happens in childhood but most of cases are latent. We had a case of 10-year-old girl who presented with acute epigastric pain and significant thickening of the stomach wall on CT. Read More

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Cost-effectiveness analysis of anti-IL-5 therapies of severe eosinophilic asthma in Spain.

J Med Econ 2021 Jan-Dec;24(1):874-882

Medicine and Specialities Department, Universidad de Alcalá (Alcalá de Henares, Madrid), Hospital Universitario Guadalajara, Guadalajara, Spain.

Aim: To analyse the cost-effectiveness of MEP with standard of care (SoC) versus other anti-IL-5 therapies approved for the treatment of severe eosinophilic asthma (SEA) patients, within the Spanish National Health System (NHS) perspective.

Methods: A Markov model with a 4-week cycle length was used to compare MEP with BEN and RES as therapies added to SoC in the management of SEA, in terms of cost per QALY gained and incremental cost-effectiveness ratio (ICER). Costs (€2019) were obtained from public sources, while utilities and transition probabilities were retrieved from literature, e. Read More

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Traumatic ulcerative granuloma with stromal eosinophilia: A puzzle.

J Oral Maxillofac Pathol 2021 Mar 19;25(Suppl 1):S42-S45. Epub 2021 Mar 19.

Department of Public Health Dentistry, Bareilly International University, Institute of Dental Sciences, Bareilly, Uttar Pradesh, India.

Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is an ulcerative condition of the oral mucosa amid a chronic course and delayed healing. It is a reactive lesion that usually affects the tongue. TUGSE is a rare mucosal lesion to aid as an ulcer or an indurated submucosal mass and might cause diagnostic problems as it mimics a traumatic or neoplastic ulcer. Read More

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Non-responsive celiac disease in children on a gluten free diet.

World J Gastroenterol 2021 Apr;27(13):1311-1320

Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA 02115, United States.

Background: Non-responsive celiac disease (NRCD) is defined as the persistence of symptoms in individuals with celiac disease (CeD) despite being on a gluten-free diet (GFD). There is scant literature about NRCD in the pediatric population.

Aim: To determine the incidence, clinical characteristics and underlying causes of NRCD in children. Read More

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Riga-Fede disease: a mimicker of malignancy.

BMJ Case Rep 2021 Mar 18;14(3). Epub 2021 Mar 18.

Otorhinolaryngology, Sri Ramachandra Medical College and Research Institute, Chennai, India.

Riga-Fede disease (RFD), also known as traumatic eosinophilic granuloma, is a benign inflammatory condition of the oral cavity that may mimic a malignant tumour. It's a rare condition mainly reported in infants. We present a unique case report of a 57-year-old man who presented to our outpatient department with foreign body sensation in the throat and swelling over the dorsum of the tongue for a period of 1 month. Read More

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Hemocytic sarcoma of the body wall in a California king crab Paralithodes californiensis.

Dis Aquat Organ 2021 Jan 28;143:13-18. Epub 2021 Jan 28.

Joint Pathology Center, 606 Stephen Sitter Ave., Silver Spring, MD 20910, USA.

Neoplasia is rarely reported in decapod crustaceans, and sarcoma has not been previously reported in any crab species. A California king crab Paralithodes californiensis with a recent history of autotomy (4 legs lost) and anorexia was found dead. Grossly, the crab had a pigmented ulcer on the right cheliped merus. Read More

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January 2021

Diagnostic Delay in Patients with Eosinophilic Gastritis and/or Duodenitis: A Population-Based Study.

J Allergy Clin Immunol Pract 2021 05 10;9(5):2050-2059.e20. Epub 2021 Jan 10.

Allakos Inc., Redwood City, Calif.

Background: Eosinophilic gastritis and/or eosinophilic duodenitis (EG/EoD) is characterized by persistent symptoms and elevated eosinophils in the gastrointestinal tract. Limited disease awareness and lack of diagnostic guidelines suggest that patients may remain undiagnosed or endure diagnostic delay.

Objective: To characterize the path to diagnosis for patients with EG/EoD in a representative population. Read More

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Analysis and Follow up of Endoscopy Results in 1099 Patients with Terminal Ileum Lesions.

Can J Gastroenterol Hepatol 2020 4;2020:8838613. Epub 2020 Dec 4.

University of Delaware, Newark, DE, USA.

Objective: We aim to analyze the diagnostic yield, diagnostic accuracy, and delayed diagnosis of patients with terminal ileum lesions, providing follow-up suggestions for suspected patients.

Methods: We carried out an analysis of 1099 patients who had terminal ileum lesions in our hospital from 2009 to 2019. The endoscopy reports and histopathology reports of terminal ileal biopsies were recorded. Read More

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December 2020

[The eosinophilic esophagitis and IgG4-related disease involving the esophagus].

Ter Arkh 2020 Sep 3;92(8):100-107. Epub 2020 Sep 3.

Mechnikov North-Western State Medical University.

The study of eosinophilic esophagitis has become a dynamic field with an evolving understanding of the pathogenesis, diagnosis, and treatment. Immunoglobulin G4 (IgG4)-related disease exhibits systemic involvement but very rarely involves the esophagus. The article presents a clinical case: the history of ulcer and stricture of the esophagus in a young man of 17 years. Read More

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September 2020

The Use and Misuse of Proton Pump Inhibitors: An Opportunity for Deprescribing.

J Am Med Dir Assoc 2021 01 13;22(1):15-22. Epub 2020 Dec 13.

Department of Medicine, Geriatric Medicine, Geriatric Medicine Fellowship Program, Montefiore Medical Center, Wakefield Campus, Bronx, NY, USA; Albert Einstein College of Medicine, Bronx, NY, USA. Electronic address:

Proton pump inhibitors (PPIs) are proven medications of choice for gastroesophageal reflux disease (GERD), acid-related disorders, erosive esophagitis, Barrett esophagus, prevention of gastrointestinal bleeding while on nonsteroidal anti-inflammatory drugs, eosinophilic esophagitis, peptic ulcer disease, stress ulcer prophylaxis in critically ill patients, and other indications. Best practice guidelines from several sources on the appropriate indications and duration of PPI therapy have been summarized for easy assimilation. Individualized decision with regard to PPI use is illustrated by case vignettes; best approaches are provided. Read More

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January 2021

Subcutaneous administration of triamcinolone as part of the management of feline eosinophilic keratoconjunctivitis.

J Feline Med Surg 2021 Jun 3;23(6):575-583. Epub 2020 Nov 3.

Department of Surgical and Radiological Sciences, University of California-Davis, Davis, CA, USA.

Objectives: The aim of this retrospective case-control study was to report the efficacy of subcutaneous triamcinolone as part of a regimen for feline eosinophilic keratoconjunctivitis (FEK).

Methods: Records and clinical photographs were reviewed and lesions semiquantitatively graded for cats with cytologically confirmed FEK. Clinical data were compared between a study population of nine cats (11 eyes) treated with, and a reference population of seven cats (eight eyes) treated without, a median of 0. Read More

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Review - Helicobacter pylori and non-malignant upper gastro-intestinal diseases.

Helicobacter 2020 Sep;25 Suppl 1:e12738

Department of Gastroenterology & Institute for Digestive Research, Lithuanian University of Health Sciences, Kaunas, Lithuania.

This review takes into account recent publications focusing on the relationship between Helicobacter pylori infection and non-malignant diseases of the upper gastro-intestinal tract. The authors have summarized current knowledge on associations between the H pylori infection and non-malignant upper GI conditions including gastroesophageal reflux disease (GERD), Barrett's esophagus, eosinophilic esophagitis (EOE), peptic ulcer disease (PUD), H pylori gastritis, celiac disease and functional dyspepsia. In the field of GERD, current data focusing on different locations of H pylori infection detect significant differences between antrum- and corpus predominant gastritis explainable by different changes in acid secretion in different gastric niches. Read More

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September 2020

Solitary Duodenal Ulcer Causing Biliary Obstruction Requiring Rendezvous Procedure in a Pediatric Patient With Eosinophilic Gastroenteritis.

Cureus 2020 Jul 24;12(7):e9377. Epub 2020 Jul 24.

Gastroenterology, Johns Hopkins All Children's Hospital, St. Petersburg, USA.

Eosinophilic gastroenteritis (EGE) is an uncommon disease characterized by immune cell-mediated inflammation of the gastrointestinal (GI) tract resulting in vague abdominal symptoms, most commonly nausea, vomiting, diarrhea, and abdominal pain. We report the case of a 16-year-old male presenting with a six-week history of progressive pruritus, jaundice, fatigue, abdominal pain, acholic stools, and dark-colored urine. This patient was diagnosed via endoscopy with biliary obstruction caused by a large, solitary, duodenal ulcer secondary to EGE. Read More

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Eosinophilic gastroenteritis as a cause of non-Helicobacter pylori, non-gastrotoxic drug ulcers in children.

BMC Gastroenterol 2020 Aug 20;20(1):280. Epub 2020 Aug 20.

Department of Pediatrics, Seoul National University Bundang Hospital, Seoul National University, 82, Gumi-ro 173 Beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do, 13620, South Korea.

Background: While Helicobacter pylori (H. pylori) ulcers has declined recently, H. pylori-negative and/or gastrotoxic drug-negative peptic ulcers (HNGN-PU) has increased. Read More

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Asymptomatic coronary aneurysms in a patient with eosinophilic granulomatosis with polyangiitis who developed a digital gangrene.

Mod Rheumatol Case Rep 2021 01 25;5(1):130-136. Epub 2020 Aug 25.

Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan.

A 33-year-old male with a history of bronchial asthma and allergic rhinitis was diagnosed with eosinophilic granulomatosis with polyangiitis (EGPA) eight years ago. The diagnosis was based on the presence of fever, remarkable eosinophilia, and painful digital ulcer. His signs and symptoms improved with a moderate dose of glucocorticoids. Read More

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January 2021

Eosinophilic Gastroenteritis-associated Duodenal Ulcer Successfully Treated with Crushed Budesonide.

Intern Med 2020 Sep 15;59(18):2249-2254. Epub 2020 Jun 15.

Departments of Gastroenterology, National Hospital Organization Hakodate National Hospital, Japan.

Eosinophilic gastroenteritis (EGE)-associated duodenal ulcer is rare and its endoscopic and pathological features remain poorly described. A 15-year-old boy was referred to our hospital for further examination and treatment of duodenal ulcer. Esophagogastroduodenoscopy (EGD) revealed two A2-stage duodenal ulcers on the duodenal bulb. Read More

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September 2020

Eosinophilic ulcer mimicking malignancy of the lower lip: A case report.

Clin Case Rep 2020 May 3;8(5):804-807. Epub 2020 Mar 3.

Mazandaran University of Medical Sciences Sari Iran.

Eosinophilic ulcer (EU) is a rare self-limiting chronic benign lesion of the oral mucosa. It is an uncommon and benign disease, which may leading to diagnostic difficulties. Biopsy is recommended to rule out any malignant etiology. Read More

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Gastric crystal-storing histiocytosis with concomitant mucosa-associated lymphoid tissue lymphoma.

J Pathol Transl Med 2020 Jul 22;54(4):332-335. Epub 2020 May 22.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Goyang.

Crystal-storing histiocytosis (CSH) is a rare entity that is characterized by intrahistiocytic accumulation of crystallized immunoglobulins. CSH is not a malignant process per se, but the majority of CSH cases are associated with underlying lymphoproliferative disorder. Although CSH can occur in a variety of organs, gastric CSH is very rare. Read More

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Upper Gastrointestinal Bleed in a Young Male- A Rare Presentation of Eosinophilic Gastroenteritis.

Cureus 2020 Feb 20;12(2):e7059. Epub 2020 Feb 20.

Internal Medicine, Avnentura Hosptial and Medical Center, Aventura, USA.

Eosinophilic gastroenteritis (EGE) is a rare idiopathic disease affecting multiple organs (stomach and small intestine) of the digestive tract. It is characterized by eosinophilic infiltration of the bowel wall to a variable depth and symptoms associated with gastrointestinal tract disease. The prevalence of this condition is ranging from 8 and 28 per 100,000. Read More

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February 2020

Multiple ulcerations and perforation in the small intestine after steroid treatment in eosinophilic granulomatosis with polyangiitis: a case report and literature review.

Cardiovasc Pathol 2020 Jul - Aug;47:107193. Epub 2019 Dec 18.

Department of Cellular and Organ Pathology, Graduate School of Medicine, Akita University, Akita, Japan.

Eosinophilic granulomatosis with polyangiitis (EGPA), formerly called Churg-Strauss syndrome, is an uncommon disease with pathological features consisting of systemic necrotizing vasculitis, eosinophilic infiltration, and granulomatous or nongranulomatous extravascular eosinophilic inflammation. EGPA preferentially affects certain organ systems, including the airways, peripheral nerves, heart, kidney, and gastrointestinal tract. Although gastrointestinal involvement, such as ulcerations, is common in EGPA, gastrointestinal perforation is relatively uncommon and is associated with a poor prognosis. Read More

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Lessons of the month 3: Duodenal perforation after polystyrene sulfonate.

Clin Med (Lond) 2020 01;20(1):107-109

Prince of Wales Hospital, Hong Kong

Ion-exchange resins, sodium or calcium polystyrene sulfonate, are commonly used medications for management of hyperkalaemia. However, the drug can be associated with serious bowel injury. We report a case of a renal transplant recipient who developed duodenal ulcer perforation secondary to the use of calcium polystyrene sulfonate. Read More

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January 2020

Association Between Endoscopic and Histologic Findings in a Multicenter Retrospective Cohort of Patients with Non-esophageal Eosinophilic Gastrointestinal Disorders.

Dig Dis Sci 2020 07 26;65(7):2024-2035. Epub 2019 Nov 26.

Center for Esophageal Diseases and Swallowing and Center for Gastrointestinal Biology and Disease, Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina School of Medicine, CB #7080, Chapel Hill, NC, 27599, USA.

Background: Little is known about the endoscopic and histologic findings of non-esophageal eosinophilic gastrointestinal diseases (EGID).

Aim: To characterize the presenting endoscopic and histologic findings in patients with eosinophilic gastritis (EG), eosinophilic gastroenteritis (EGE), and eosinophilic colitis (EC) at diagnosis and 6 months after initiating the treatment.

Methods: We conducted a retrospective cohort study at 6 US centers associated with the Consortium of Eosinophilic Gastrointestinal Researchers. Read More

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Traumatic ulcerative granuloma with stromal eosinophilia - clinical case report, literature review, and differential diagnosis.

World J Surg Oncol 2019 Nov 9;17(1):184. Epub 2019 Nov 9.

Department of Oral and Craniomaxillofacial Surgery, University Hospital Basel, Spitalstrasse 21, CH-4031, Basel, Switzerland.

Background: Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is a rare self-limiting condition of the oral mucosa. The lesion manifests as an isolated ulcer that can be either asymptomatic or associated with mild to severe pain, and in most cases, it affects the tongue. TUGSE lesions may mimic malignancy such as squamous cell carcinoma, CD30 positive lymphoproliferative disorder, or infectious diseases such as primary syphilis, tuberculosis, or Epstein-Barr virus mucocutaneous ulcer. Read More

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November 2019

Metastatic Crohn Disease: A Clinicohistological Appraisal From a Tertiary Care Center in India.

Am J Dermatopathol 2020 Jul;42(7):506-512

Departments of Histopathology and Dermatology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Background: Granulomatous dermatitis due to noncontiguous involvement of Crohn disease (CD) of the gut has been described as metastatic CD (MCD). MCD is the rarest form of cutaneous manifestations of CD. This study aims to analyze the clinicohistological features of MCD in a tertiary care center of India. Read More

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Gastrointestinal involvement in patients with vasculitis: IgA vasculitis and eosinophilic granulomatosis with polyangiitis.

Endosc Int Open 2019 Nov 22;7(11):E1333-E1343. Epub 2019 Oct 22.

Division of Gastroenterology, Iwate Medical University, Morioka, Japan.

 Among vasculitides, IgA vasculitis (IgAV) and eosinophilic granulomatosis with polyangiitis (EGPA) frequently damage the gastrointestinal tract. However, only a few studies have investigated the entire gastrointestinal tract in patients with IgAV or EGPA by endoscopy. The aim of this study was to clarify endoscopic characteristics of patients with IgAV and those with EGPA. Read More

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November 2019

You're the Flight Surgeon.


Aerosp Med Hum Perform 2019 Nov;90(11):986-988

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November 2019

An Autopsy Case of a 5-Year-Old Child with Acute Pancreatitis Caused by Eosinophilic Granulomatosis with Polyangiitis-like Necrotizing Vasculitis.

Case Rep Rheumatol 2019 2;2019:9053747. Epub 2019 Sep 2.

Department of Diagnostic Pathology, Seirei Mikatahara Hospital, 3453 Mikataharacho, Hamamatsu 433-8558, Japan.

In children, acute pancreatitis has been reported in IgA vasculitis, Kawasaki disease, systemic lupus erythematosus-associated vasculitis, and juvenile dermatomyositis-associated vasculitis. However, its frequency in these vasculitides has been shown to be low. In other childhood-onset vasculitides, acute pancreatitis is seldom reported. Read More

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September 2019

Review: Helicobacter pylori and non-malignant upper gastrointestinal diseases.

Helicobacter 2019 Sep;24 Suppl 1:e12637

Medical Department II, University Hospital, LMU, Munich, Germany.

This review covers recent publications investigating the relationship between Helicobacter pylori infection and gastroesophageal reflux disease, Barrett's esophagus, eosinophilic esophagitis, peptic ulcer disease (PUD), H pylori gastritis, and functional dyspepsia. In the area of gastroesophageal reflux disease, new data suggest that reflux may have a role in the transmission of H pylori infection. In addition to several observational studies, data on alterations in esophageal physiology in patients with H pylori infection are presented. Read More

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September 2019

[Langerhans cell histiocytosis revealed by a temporomandibular joint disorder: Report of a case and review of the craniofacial expressions].

Rev Med Interne 2020 Jan 29;41(1):50-53. Epub 2019 Aug 29.

Service de chirurgie maxillo-faciale et stomatologie, centre hospitalo-universitaire de Rouen, 1, rue de Germont, 76000 Rouen, France; Laboratoire d'anatomie, faculté de médecine de Rouen, 22, boulevard Gambetta, 76000 Rouen, France; Institut national de la santé et de la recherche médicale (Inserm), LIMICS UMR-1142, 76000 Rouen, France. Electronic address:

Introduction: Langerhans cell histiocytosis (HL) is a rare disease that can affect all tissues. Oral manifestations such as mucosal ulcer and tooth mobility are often the first signs of the disease. We report a rare case of mandibular condyle unifocal HL mimicking a temporomandibular joint disorder. Read More

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January 2020