Search Our Scientific Publications & Authors

J Vet Med Sci 2019 Apr 18. Epub 2019 Apr 18.

Iwate University Small Animal Veterinary Internal Science.

A 12-year-old, male miniature dachshund has an ulcer on the footpad of the right hind limb. Despite treatment for longer than 6 months, the ulcer did not heal. Biopsy of the lesion was done to make a definitive diagnosis. Read More

G Ital Dermatol Venereol 2019 Feb 4. Epub 2019 Feb 4.

Dermatology, Department of Specialized, Diagnostic and Experimental Medicine, University of Bologna, Bologna, Italy.

Vet Ophthalmol 2019 Jan 31. Epub 2019 Jan 31.

Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, California.

Objective: (a) To evaluate the epidemiology of equine eosinophilic keratoconjunctivitis (EK) in the western United States, (b) to ascertain the efficacy of keratectomy and diamond burr debridement vs medical management alone, (c) to determine the efficacy of various medical therapies, and (d) to further characterize the histopathologic findings of the disease in horses.

Animals Studied: Twenty-nine horses (47 eyes) diagnosed with EK from 1993 to 2017.

Procedure: Retrospective medical record review; owner questionnaire. Read More

Rev Pneumol Clin 2018 12 24;74(6):516-519. Epub 2018 Nov 24.

Service de pneumologie, CHL, Strassen, Luxembourg.

Gastroenterol Hepatol (N Y) 2018 Mar;14(3):169-175

Dr Khan is a third year gastroenterology fellow and Dr Howden is the Hyman Professor of Medicine and Chief of the Division of Gastroenterology at the University of Tennessee Health Science Center in Memphis, Tennessee.

Proton pump inhibitors (PPIs) have been in use since the early 1990s and play a crucial role in the management of a number of conditions affecting the upper gastrointestinal tract, including gastroesophageal reflux disease, Barrett esophagus, eosinophilic esophagitis, and dyspepsia. PPIs also play an important role in the treatment of infection and in the prevention of upper gastrointestinal tract ulcers and bleeding among patients taking antiplatelet therapy and/or nonsteroidal anti-inflammatory drugs. Despite recent concerns regarding the long-term safety of PPIs, their risk-benefit profiles strongly favor their appropriate use in patients who have genuine indications for them. Read More

Indian J Pathol Microbiol 2018 Apr-Jun;61(2):255-257

Department of General Pathology, Christian Medical College, Vellore, Tamil Nadu, India.

Epstein-Barr virus-positive mucocutaneous ulcer (EBVMCU) comprises part of the spectrum of B-cell lymphoproliferative disorders, reported in settings of immunosenescence and iatrogenic immunosuppression, affecting the oropharyngeal mucosa, skin, and gastrointestinal tract. We report a case of a 59-year-old female, known case of rheumatoid arthritis on methotrexate (MTX) for 15 years, who presented with an ulcer in the inner aspect of her cheek region for 2 years. Clinical examination revealed an infiltrative lesion involving the lower gingivobuccal sulcus of size 2 cm × 3 cm extending to the alveolus with level I lymph nodes, suspicious for carcinoma buccal mucosa. Read More

Vet Dermatol 2018 Jun 6;29(3):258-e96. Epub 2018 Apr 6.

Department of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126, Perugia, Italy.

Background: Feline herpesvirus ulcerative dermatitis is an uncommon skin disease in cats, with a predominantly facial distribution characterized by massive infiltration of eosinophils and, occasionally, predominant neutrophils.

Objective: To describe the clinical and histopathological features of a putative atypical case of feline herpesvirus dermatitis.

Animal: A 10-month-old, intact male, European cat was presented with chronic monolateral ulcerative dermatitis with adherent crusts on the left pinna. Read More

Gastroenterology 2018 04 8;154(5):1209-1214. Epub 2018 Mar 8.

Division of Gastroenterology, Northwestern University Feinberg School of Medicine, Chicago, Illinois. Electronic address:

Open Dent J 2018 29;12:19-23. Epub 2018 Jan 29.

Department of Stomatology, Oral Medicine Division, School of Dentistry, University of São Paulo, São Paulo, SP. Brazil.

Objective: This article describes a case of an Oral Eosinophilic Ulcer (OEU) in an otherwise healthy 31-year-old white woman.

Introduction: The importance of reporting this case was the presence of recurrent episodes with lesions appearing in different areas of the oral mucosa, a type of manifestation not commonly associated with this disease. A typical manifestation of OEU occurs as a single ulceration that goes into healing after an incisional biopsy, a procedure usually required for a proper diagnosis of the disease. Read More

Biol Trace Elem Res 2018 Sep 4;185(1):36-47. Epub 2018 Jan 4.

Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8555, Japan.

Lanthanum (La) carbonate (LC) is one of the most potent phosphate binders that prevents the elevation of serum phosphate levels in patients with end-stage renal diseases undergoing dialysis. LC binds strongly to dietary phosphate and forms insoluble complexes that pass through the gastrointestinal tract. La deposition in patients treated with LC is a recently documented finding particularly observed in gastric mucosa. Read More

J Nippon Med Sch 2017 ;84(6):286-290

Department of Dermatology, Nippon Medical School.

A 72-year-old man was referred to our hospital for treatment of an ulcer that had been growing on his back for 10 years. Physical examination showed an ulcerated tumor from the neck to the back and swollen cervical lymph nodes. The tumor size was 12×9 cm. Read More

Ann Diagn Pathol 2017 Dec 16;31:50-55. Epub 2017 Jun 16.

Weill Cornell Medicine, 1300 York Ave, New York, NY 10065, USA. Electronic address:

Eosinophilic ulcer of the oral mucosa (EUOM) is a rare, benign, self-resolving lymphoproliferative disorder, which typically presents with asymptomatic to mildly tender ulcers. Histological findings of EUOM are characterized by a polymorphic infiltrate with many eosinophils often extending into the underlying muscle. Although this entity is well documented within the dental literature, it is not well known to physicians. Read More

J Dermatol 2018 Feb 15;45(2):220-223. Epub 2017 Nov 15.

Department of Dermatology, Kansai Medical University Medical Center, Osaka, Japan.

Case 1 was a 75-year-old Japanese man who presented with a poorly demarcated, dark-red nodule with a destructive defect in the center, measuring 3 cm × 2 cm on the right wing of his nose. The histological diagnosis was a common form of infundibular squamous cell carcinoma. Atypical neoplastic cells radiated from the wall of a follicular infundibulum. Read More

Clin Endosc 2018 May 26;51(3):285-288. Epub 2017 Oct 26.

Department of Internal medicine, Digestive Disease Research Institute, Wonkwang University College of Medicine, Iksan, Korea.

Esophagogastroduodenoscopy for cancer screening was performed in a 55-year-old woman as part of a health screening program, and revealed a depressed lesion approximately 20 mm in diameter in the lesser curvature of the mid-gastric body. Several biopsy specimens were collected as the lesion resembled early gastric cancer; however, histopathologic evaluation revealed chronic active gastritis with an ulcer and amorphous eosinophilic material deposition. Congo red staining identified amyloid proteins, and apple-green birefringence was shown using polarized light microscopy. Read More

Cutis 2017 Aug;100(2):E28-E31

Wilford Hall Ambulatory Surgical Center, San Antonio Uniformed Services Health Education Consortium, Texas, USA.

Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is an underreported diagnosis in dermatologic literature. Rapid expansion with an ulcerative clinical appearance often provokes fear of malignancy despite its benign nature. Traumatic ulcerative granuloma with stromal eosinophilia is thought to be a reactive tissue response to trauma, but CD30 mononuclear cells within a TUGSE lesion suggests the possibility of an underlying lymphoproliferative disorder. Read More

J Oral Maxillofac Pathol 2017 May-Aug;21(2):321

Department of Oral Pathology and Microbiology, Saraswati Dental College, Lucknow, Uttar Pradesh, India.

Eosinophilic ulcer (EU) is a rare self-limiting chronic benign ulcerative lesion of the oral mucosa often misdiagnosed as oral malignancy. Its etiopathogenesis is ambiguous, but trauma plays an important role in the development. Microscopically, it is characterized by a polymorphic inflammatory infiltrate with a prominent eosinophilic component and large mononuclear cells extending deep into the submucosa, underlying muscle and salivary glands. Read More

Medicine (Baltimore) 2017 Sep;96(37):e8075

aDepartment of Gastroenterology and Hepatology, Jinling Hospital, School of Medicine, Southern Medical University bDepartment of Gastroenterology and Hepatology, Jinling Hospital cDepartment of Gastroenterology and Hepatology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu, China.

Rationale: Eosinphilic gastroenteritis (EG) is a gastrointestinal disorder characterized by eosinophilic infiltration with various manifestations. The diagnosis is usually confirmed by an endoscopic biopsy, which is considered a safe and routine procedure for the majority.

Patient Concerns: We report a 54-year-old male who was presented with intermittent periumbilical pain and melena, and only revealed verrucous gastritis by endoscopy. Read More

Helicobacter 2017 Sep;22 Suppl 1

Institute of Clinical and Preventive Medicine & Faculty of Medicine, University of Latvia, Riga, Latvia.

A substantial decrease in Helicobacter pylori-associated peptic ulcer disease has been observed during the last decades. Drug-related ulcers as well as idiopathic ulcers are becoming predominant and are more refractory to treatment; however, H. pylori infection still plays an important role in ulcer bleeding and recurrence after therapy. Read More

Rev Med Suisse 2017 Jan;13(544-545):49-53

Service de gastroentérologie et hépatologie, HUG, 1211 Genève 14.

This article aims to detail the major innovations occurred in Gastro-enterology in 2016, including the introduction of a new molecule, the vonoprazan, for the treatment of refractory gastroesophagal reflux disease (GERD) and a new way of eradication of H. pylori. The possibility to use an intermittent dose of PPI rather than continuously in severe gastric and duodenal ulcers after successful endoscopic hemostasis is also discussed as well as the withdrawal of corticosteroids in the treatment of autoimmune pancreatitis. Read More

Bladder Cancer 2017 Apr 27;3(2):133-138. Epub 2017 Apr 27.

Department of Urology, University of Michigan Health System, Ann Arbor, MI, USA.

A post-bladder tumor resection dose of MMC can reduce non-invasive papillary (pTa) bladder cancer recurrences by up to 40%; this treatment is recommended in both the AUA and EUA non-muscle-invasive bladder cancer guidelines. A common complication of this treatment is eosinophilic cystitis. Symptoms range from mild urinary frequency and urgency to debilitating pain and dysuria. Read More

J Fish Dis 2017 Oct 23;40(10):1341-1350. Epub 2017 Jan 23.

Wildlife, Exotic and Aquatic Pathology- Special Task Force for Activating Research, Department of Veterinary Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.

In 2013, an outbreak of ulcerative disease associated with ranavirus infection occurred in barcoo grunter, Scortum barcoo (McCulloch & Waite), farms in Thailand. Affected fish exhibited extensive haemorrhage and ulceration on skin and muscle. Microscopically, the widespread haemorrhagic ulceration and necrosis were noted in gill, spleen and kidney with the presence of intracytoplasmic eosinophilic inclusion bodies. Read More

Gastroenterol Hepatol Bed Bench 2017 ;10(Suppl1):S161-S164

Behbood Gastroenterology and Liver Diseases Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Eosinophilic gastroenteritis is a rare inflammatory disease, defined by infiltration of eosinophils in gastrointestinal (GI) tract, but the etiology of this disorder is unknown. Depends on the involvement region of Eosinophilic gastroenteritis, GI symptoms are variable including abdominal pain, malabsorption, gastric and duodenal ulcer. Due to its non-specific symptoms, the diagnosis is based on upper GI endoscopy followed by histopathological examination of the biopsies, which shows eosinophilic infiltration in different layers of GI tract. Read More

BMC Med 2016 11 9;14(1):179. Epub 2016 Nov 9.

Division of Pharmacology, Department of Clinical & Experimental Medicine, University of Pisa, Pisa, Italy.

Background: The introduction of proton pump inhibitors (PPIs) into clinical practice has revolutionized the management of acid-related diseases. Studies in primary care and emergency settings suggest that PPIs are frequently prescribed for inappropriate indications or for indications where their use offers little benefit. Inappropriate PPI use is a matter of great concern, especially in the elderly, who are often affected by multiple comorbidities and are taking multiple medications, and are thus at an increased risk of long-term PPI-related adverse outcomes as well as drug-to-drug interactions. Read More

Pediatr Transplant 2016 Nov 13;20(7):994-999. Epub 2016 Jul 13.

Hepatology and Liver Transplantation, Hospital Sirio-Libanes, Sao Paulo, SP, Brazil.

The association between LT and gastrectomy is not common. Only two studies reported the gastrectomy/LT association in children. Here, we report three children who underwent LT who required a concomitant or sequential gastrectomy for different reasons. Read More

Gac Med Mex 2016 Sep;152 Suppl 1:74-83

Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, México.

Diet is considered an important triggering factor for gastrointestinal symptoms whose physiopathology includes not only measurable, inflammatory reactions, but also functional disorders, where no organic effects may be measured or demonstrated. Moreover, the prevalence of the perceived intolerance to certain foods ranges from 20-25% (within the general population) to 50-70% in diseases like irritable bowel syndrome. This intolerance has been observed particularly after the consumption of milk and dairy products, which are frequently considered as causative of gastrointestinal symptoms, thus limiting their ingestion. Read More

Histopathology 2017 Jan 12;70(2):203-210. Epub 2016 Oct 12.

MRC Cancer Unit, Hutchison-MRC Research Centre, Cambridge, UK.

Aims: Reflux symptoms are highly prevalent and non-specific; hence, in the absence of alarm symptoms, endoscopy referral decisions are challenging. This study evaluated whether a non-endoscopic Cytosponge could detect benign oesophageal pathologies and thus have future potential in triaging patients with persistent symptoms.

Methods And Results: Two complementary cohorts were recruited: (i) patients with reflux symptoms and no prior endoscopy (n = 409), and (ii) patients with reflux symptoms referred for endoscopy (n = 411). Read More

Natl J Maxillofac Surg 2015 Jul-Dec;6(2):237-40

Department of Anatomical Pathology, Laverty Pathology, North Ryde, NSW 2113, Australia.

Eosinophilic ulcer of the oral mucosa is considered to be a benign, reactive, and self-limiting lesion, with unclear pathogenesis, manifesting as a rapidly developing solitary ulcer. We report a case of a 42-year-old man who presented with a chronic indurated ulcer of buccal mucosa adjacent to the right upper wisdom tooth. Histopathological examination showed polymorphic inflammatory infiltrate, rich in eosinophilis, involving the superficial mucosa, and the deeper muscle layer. Read More

Acta Gastroenterol Belg 2016 Apr-Jun;79(2):245-50

Therapy with proton-pump inhibitors (PPIs) results in remission in at least one third of patients with esophageal eosinophilia, presumably because of both their acid-related and anti-inflammatory mechanisms of action. However, eosinophilic esophagitis (EoE) may also develop during therapy with PPIs. We present a case series of four children who were initially diagnosed with infectious esophagitis, gastroesophageal reflux disease or gastric ulcer, who had no eosinophilic infiltration of the esophagus, but subsequently developed symptoms, endoscopic features and histological picture of typical EoE. Read More

Ann Dermatol Venereol 2016 Oct 21;143(10):616-621. Epub 2016 Jun 21.

Service de dermatologie, hôpital Saint-André, CHU de Bordeaux, rue Jean-Burguet, 33076 Bordeaux, France. Electronic address:

Introduction: Cutaneous tuberculosis (CT) is rare in industrialized countries. Given the clinicopathological polymorphism and the difficulty of isolating the pathogen, diagnosis can be difficult. The condition may be associated with other known locations of the disease or in rare cases, it may be a tell-tale sign, as in our case, in which leg ulcers revealed paucisymptomatic disseminated tuberculosis. Read More

Am J Case Rep 2016 Apr 18;17:259-63. Epub 2016 Apr 18.

Department of Internal Medicine, Ubekosan Central Hospital Corporation, Ube-city, Yamaguchi, Japan.

Background: The clinical manifestations of eosinophilic gastroenteritis are nonspecific and vary depending on which layer of the gastrointestinal tract is involved. Computed tomography (CT) is valuable for detecting and characterizing gastrointestinal wall abnormalities.

Case Report: We report a case of eosinophilic gastroenteritis that formed a chamber in the rigid duodenal wall of a 67-year-old woman. Read More

Clin Endosc 2016 Jul 21;49(4):387-90. Epub 2016 Mar 21.

Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Ube, Japan.

A 64-year-old man was found to have a nodule in his right lung. He also complained of nausea and abdominal pain during the clinical course. Esophagogastroduodenoscopy revealed a duodenal ulcer associated with severe stenosis and a suspicion of malignancy. Read More

BMJ Case Rep 2016 Feb 17;2016. Epub 2016 Feb 17.

Department of Pediatric Rheumatology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.

A 14-year-old boy previously misdiagnosed as having cutaneous anthrax was referred with a 2-month history of multiple wide and deep ulceronecrotic lesions in the lower extremities, which occurred after contact with animals. Skin biopsy was compatible with vasculitis. Further examination at our hospital elicited eosinophilia and a history of asthma. Read More

Pediatr Gastroenterol Hepatol Nutr 2015 Dec 23;18(4):253-60. Epub 2015 Dec 23.

Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.

Purpose: The aim of the present study was to investigate the clinical features and outcome of eosinophilic gastroenteritis (EGE) in children.

Methods: Our study enrolled 24 children who were diagnosed with EGE from 1993 to 2014 at the Department of Pediatrics, Seoul National University Children's Hospital. The patients' clinical manifestations, treatments, and outcomes were reviewed from the medical records. Read More

BMJ Case Rep 2016 Jan 12;2016. Epub 2016 Jan 12.

Teikyo University Chiba Medical Center, Ichihara, Japan.

World J Gastroenterol 2015 Nov;21(44):12709-12

Kevin M Riggle, Kimberly J Riehle, Department of General Surgery, University of Washington, Seattle, WA 98195, United States.

Spontaneous perforation of a duodenal ulcer secondary to allergic eosinophilic gastroenteritis (EGE) has not been previously reported. We present such a case in a teenager who presented with peritonitis. After exploration and operative repair of his ulcer, he continued to experience intermittent abdominal pain, and further evaluation revealed eosinophilic gastroenteritis in the setting of multiple food allergies. Read More

J Pathol Transl Med 2015 Nov 30;49(6):525-30. Epub 2015 Sep 30.

Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Eosinophilic ulcer of the oral mucosa (EUOM) is a very rare, benign, self-limiting ulcerative lesion of the oral cavity of unknown pathogenesis, and belongs to the same spectrum of CD30(+) T-cell lymphoproliferative disease (LPD) of the oral mucosa. The etiology and pathogenesis of the disease are unknown. We report two cases in children who were initially diagnosed with EUOM and CD30(+) T-cell LPD, respectively. Read More

An Bras Dermatol 2015 May-Jun;90(3 Suppl 1):88-90

Clinica Dermatologica, La Sapienza University of Rome, Rome, IT.

Eosinophilic ulcer of the oral mucosa is a rare, self-limiting, chronic and benign lesion of unknown pathogenesis that affects the oral mucosa. We present the case of a 65 year-old Caucasian female with a five month history of a painful ulcer on the lateral side of her tongue. The ulcer was not adhered to the underlying structures and there was no evidence of regional lymph node involvement. Read More

Int J Surg Pathol 2015 Dec 26;23(8):667-72. Epub 2015 Aug 26.

Western Connecticut Health Network, Danbury, CT, USA.

Russell bodies represent a cellular response to overstimulation of plasma cells, leading to the accumulation of abundant, nondegradable, condensed immunoglobulin in dilated rough endoplasmic reticulum cisternae. Russell body gastritis was first described 1998 by Tazawa and Tsutsumi. Since then only 39 cases involving the gastrointestinal tract have been reported in English literature, which include Russell body gastritis, duodenitis, and esophagitis. Read More

Clin Gastroenterol Hepatol 2015 Dec 10;13(13):A23-4. Epub 2015 Aug 10.

Department of Gastroenterology and Hepatology, Gunma University Hospital, Maebashi, Japan.

Dtsch Med Wochenschr 2015 Jul 31;140(15):1166-72. Epub 2015 Jul 31.

Innere Medizin/Klinik II, Helios Klinikum Krefeld.

Non cardiac chest pain (NCCP) are recurrent angina pectoris like pain without evidence of coronary heart diesease in conventional diagnostic evaluation. The prevalence of NCCP is up to 70% and may be detected in this order at all levels of the medical health care system (general practitioner, emergency department, chest pain unit, coronary care). Reduction of quality of life in NCCP is comparable, partially even higher compared to cardiac chest pain. Read More

BMJ Case Rep 2015 Jun 11;2015. Epub 2015 Jun 11.

Department of Dermatology and Venereology, Hospital de Braga, Braga, Portugal.

Cryoglobulinaemic vasculitis is a complication of hepatitis C virus (HCV) infection, responding to treatment with pegylated interferon (peg-IFN)/ribavirin (RIB), but vasculitis may first appear after treatment with peg-IFN/RIB. A 35-year-old man with HCV infection presented to our department with a 2-month history of a 3.3 × 3 cm ulcer localised on the right shin, with a regular border, on a violaceous base. Read More

PLoS One 2015 5;10(6):e0128110. Epub 2015 Jun 5.

Department of Pathology, Seoul National University Boramae Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.

The aim of this study was to investigate histomorphological and immunophenotypic features in pill-induced esophagitis. We comparatively evaluated the histomorphological, immunophenotypic features of pill-induced esophagitis vs. reflux esophagitis, as well as clinical information and endoscopic findings. Read More

Clin J Gastroenterol 2015 Aug 3;8(4):179-85. Epub 2015 Jun 3.

Department of Gastroenterology, Gifu Prefectural General Medical Center, Gifu, Japan,

A boy in his early teens visited our hospital with chief complaints of hematemesis and tarry stools. Upper gastrointestinal endoscopy identified a hemorrhagic duodenal ulcer, for which hemostasis was performed using a clip. Proton pump inhibitor (PPI) administration diminished the ulcer but relapse occurred after PPI discontinuation. Read More

J Clin Diagn Res 2015 Mar 1;9(3):ZD22-3. Epub 2015 Mar 1.

Professor and Head, Department of Oral and Maxillofacial Pathology, SVS institute of Dental Sciences , Telangana, India .

Langerhans cell histiocytosis (LCH), mainly affects the skull, vertebrae, ribs and mandible in children and the long bones of adults. Symptoms range from none to pain, swelling and tenderness over the site of the lesion. This disease presents oral manifestations which can sometimes be the first expression of the condition. Read More

BMJ Case Rep 2015 Apr 2;2015. Epub 2015 Apr 2.

Department of Oral Medicine and Maxillofacial Radiology, Farooqia Dental College and Hospital, Mysore, Karnataka, India.

Eosinophilic ulcers are rare, benign, reactive and often self-limiting lesions of the oral cavity. Although the aetiology is not clear, trauma is believed to play a role in their development. Clinically, the lesion manifests as an isolated ulcer, with raised, indurated borders and a yellow fibrinous floor; because of its long duration it often leads to the suspicion of squamous cell carcinoma. Read More

Int J Colorectal Dis 2016 Feb 22;31(2):473-4. Epub 2015 Mar 22.

Section of Gastroenterology, Department of Medicine, Levanger Hospital, Kirkegata 2, 7600, Levanger, Norway.

Endosc Ultrasound 2015 Jan-Mar;4(1):78-9

Department of Pathology, Institute of Digestive and Hepatobiliary Sciences, Medanta, The Medicity, Gurgaon, Haryana, India.

Int J Clin Exp Pathol 2015 1;8(1):1041-5. Epub 2015 Jan 1.

Department of Pathology, First Affiliated Hospital and College of Basic Medicine Sciences, China Medical University China.

We presented a case of 80-year-old male with long term stomachache, marasmus and anaemia. Endoscopic evaluation suggested the malignant ulcerative tumor on the Gastric antrum, and biopsy confirmed the diagnosis of gastric adenocarcinoma. Surprisingly, in resected specimen the pathologist found a nodule just below the ulcer with clear boundary and gray-yellow section. Read More

Korean J Parasitol 2015 Feb 27;53(1):95-9. Epub 2015 Feb 27.

Department of Pathology, Kyungpook National University Medical Center, Kyungpook National University School of Medicine, Deagu 700-721, Korea.

Strongyloides stercoralis can cause systemic infection, termed strongyloidiasis, and gastrointestinal ulcer disease in immunocompromised patients. However, to our knowledge, there are no reported cases of comorbid gastric adenocarcinoma and S. stercoralis infection. Read More

Z Gastroenterol 2015 Feb 10;53(2):120-4. Epub 2015 Feb 10.

Gastro-Liga e. V., Deutsche Gesellschaft zur Bekämpfung der Krankheiten von Magen, Darm und Leber sowie von Störungen des Stoffwechsels und der Ernährung (Gastro-Liga) e. V., Gießen.

Non cardiac chest pain (NCCP) are recurrent angina pectoris like pain without evidence of coronary heart disease in conventional diagnostic evaluation. The prevalence of NCCP is up to 70 % and may be detected in this order at all levels of the medical health care system (general practitioner, emergency department, chest pain unit, coronary care). Reduction of quality of life in NCCP is comparable, partially even higher compared to cardiac chest pain. Read More