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    229 results match your criteria Eosinophilic Pustular Folliculitis

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    Eosinophilic Pustular Folliculitis in Children after Stem Cell Transplantation: An Eruption Distinct from Graft-Versus-Host Disease.
    Pediatr Dermatol 2017 May 20;34(3):326-330. Epub 2017 Mar 20.
    Department of Pediatrics, University of California, San Francisco, California.
    Eosinophilic pustular folliculitis (EPF) is a rare cutaneous disorder that typically occurs in three clinical contexts: men, individuals who are immunosuppressed or have human immunodeficiency virus, and infants. A fourth subtype occurring 2 to 3 months after hematopoietic stem cell transplantation (HSCT) has recently been described in several adults. We report two cases of EPF arising in children after HSCT. Read More

    Ofuji disease: a rare dermatosis and its challenging therapeutic approach.
    An Bras Dermatol 2016 Sep-Oct;91(5):646-648
    Instituto Lauro de Souza Lima (ILSL) - Bauru (SP), Brazil.
    Eosinophilic pustular folliculitis (EPF) or Ofuji disease is a rare dermatosis, prone to recurrence and chronicity. The peak incidence occurs in the third decade of life and its exact etiology remains unknown. Evidence suggests that the expression of adhesion molecules and the production of cytokines activate the follicular unit, but the stimulus that triggers these changes remains unclear. Read More

    Pilosebaceous targeting by isotretenoin-loaded invasomal gel for the treatment of eosinophilic pustular folliculitis: optimization, efficacy and cellular analysis.
    Drug Dev Ind Pharm 2017 Feb 2;43(2):293-304. Epub 2016 Nov 2.
    c Department of Pharmaceutics , Pharmacy College Saifai, UPRIMS & R , Saifai, Etawah , Uttar Pradesh , India.
    Context: Eosinophilic pustular folliculitis is a secondary symptom associated with HIV infection appears as levels of CD4 lymphocyte cells and T4 lymphocyte cell. Isotretinoin, an analog of vitamin A (retinoid) alters the DNA transcription mechanism and interferes in the process of DNA formation. It also inhibits the eosinophilic chemotactic factors present in sebaceous lipids and in the stratum corneum of patients suffering from this ailment. Read More

    Eosinophilic pustular folliculitis: A proposal of diagnostic and therapeutic algorithms.
    J Dermatol 2016 Nov 30;43(11):1301-1306. Epub 2016 Mar 30.
    Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
    Eosinophilic pustular folliculitis (EPF) is a sterile inflammatory dermatosis of unknown etiology. In addition to classic EPF, which affects otherwise healthy individuals, an immunocompromised state can cause immunosuppression-associated EPF (IS-EPF), which may be referred to dermatologists in inpatient services for assessments. Infancy-associated EPF (I-EPF) is the least characterized subtype, being observed mainly in non-Japanese infants. Read More

    Ofuji's disease in an immunocompetent patient successfully treated with dapsone.
    Indian Dermatol Online J 2016 Sep-Oct;7(5):399-401
    Department of Pathology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India.
    Eosinophilic pustular folliculitis or Ofuji's disease is a non-infectious eosinophilic infiltration of hair follicles, which usually presents with itchy papules and pustules in a circinate configuration. We report this case of an immunocompetent patient with erythematous papules and plaques without macropustules diagnosed as eosinophilic pustular folliculitis-a rarely reported entity outside Japan. He was successfully treated with oral dapsone. Read More

    Eosinophilic pustular folliculitis: A published work-based comprehensive analysis of therapeutic responsiveness.
    J Dermatol 2016 Aug 15;43(8):919-27. Epub 2016 Feb 15.
    Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
    Eosinophilic pustular folliculitis (EPF) is a non-infectious inflammatory dermatosis of unknown etiology that principally affects the hair follicles. There are three variants of EPF: (i) classic EPF; (ii) immunosuppression-associated EPF, which is subdivided into HIV-associated (IS/HIV) and non-HIV-associated (IS/non-HIV); and (iii) infancy-associated EPF. Oral indomethacin is efficacious, especially for classic EPF. Read More

    Eosinophilic Pustular Folliculitis Post Chemotherapy in a Patient of Non-Hogkins Lymphoma: A Case Report.
    Indian J Dermatol 2015 Sep-Oct;60(5):521
    Department of Skin (DVL), Goa Medical College, Goa, India.
    Eosinophilic pustular folliculitis (EPF) was originally described by Ofuji in Japanese patients without any systemic disease. Later it was widely associated with HIV. Lately a large number of hematological malignancies have been associated with EPF. Read More

    Eosinophilic pustular folliculitis associated with hematological disorders: A report of two cases and review of Japanese literature.
    J Dermatol 2016 Apr 12;43(4):432-5. Epub 2015 Sep 12.
    Department of Dermatology, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
    Eosinophilic pustular folliculitis (EPF) occurs in patients with hematological disorders. However, clinical information about hematological disorder-associated EPF is scarce. We report two cases of EPF associated with mantle cell lymphoma and reviewed the available published work on Japanese cases. Read More

    Eosinophilic Skin Diseases: A Comprehensive Review.
    Clin Rev Allergy Immunol 2016 Apr;50(2):189-213
    Department of Dermatology, The Second Xiangya Hospital, Central South University, 139 Middle Renmin Road, Changsha, Hunan, 410011, China.
    Eosinophilic skin diseases, commonly termed as eosinophilic dermatoses, refer to a broad spectrum of skin diseases characterized by eosinophil infiltration and/or degranulation in skin lesions, with or without blood eosinophilia. The majority of eosinophilic dermatoses lie in the allergy-related group, including allergic drug eruption, urticaria, allergic contact dermatitis, atopic dermatitis, and eczema. Parasitic infestations, arthropod bites, and autoimmune blistering skin diseases such as bullous pemphigoid, are also common. Read More

    Eosinophilic pustular folliculitis: the transition in sex differences and interracial characteristics between 1965 and 2013.
    J Dermatol 2015 Apr 10;42(4):343-52. Epub 2015 Feb 10.
    Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Department of Dermatology, Ijinkai Takeda General Hospital, Kyoto, Japan.
    Eosinophilic pustular folliculitis (EPF) is characterized by a non-infectious infiltration of eosinophils in the hair follicles. It has three variants: (i) classic EPF; (ii) immunosuppression-associated EPF, which herein is subdivided into HIV-associated (IS/HIV) and non-HIV-associated (IS/non-HIV); and (iii) infancy-associated EPF (I-EPF). The rarity of EPF has hindered our understanding of this entity. Read More

    Clinical epidemiology of eosinophilic pustular folliculitis: results from a nationwide survey in Japan.
    Dermatology 2015 9;230(1):87-92. Epub 2014 Dec 9.
    Department of Dermatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
    Background: No epidemiological study has examined the clinical characteristics, including medication use, of patients with eosinophilic pustular folliculitis (EPF).

    Objective: To describe the clinical characteristics for EPF and to examine the factors associated with the effectiveness of oral indomethacin for EPF.

    Methods: A cross-sectional study was performed of patients with EPF who visited the dermatology departments of the 67 main teaching facilities in Japan. Read More

    Eosinophilic folliculitis occurring after stem cell transplant for acute lymphoblastic leukemia: a case report and review.
    Int J Dermatol 2015 Jul 11;54(7):785-9. Epub 2014 Jul 11.
    Department of Dermatology, University of Cincinnati, Cincinnati, OH, USA.
    Background: Eosinophilic folliculitis (EF) comprises classic eosinophilic pustular folliculitis (EPF), human immunodeficiency virus (HIV)-related EF, and infantile EPF subtypes. A fourth proposed subtype describes EF associated with hematologic malignancy. Recently, EF has occurred after bone marrow or stem cell transplantation (SCT). Read More

    Widespread eosinophilic pustular folliculitis in a nonimmunocompromised patient.
    Med Princ Pract 2014 15;23(5):475-7. Epub 2014 Apr 15.
    Department of Dermatology, San Cecilio University Hospital, Granada, Spain.
    Objective: We present a case of eosinophilic pustular folliculitis, a rare dermatosis which is often associated with HIV infection or internal malignancies.

    Clinical Presentation And Intervention: We report the case of a 66-year-old man with a medical history of hypertension. Histopathological examination showed a dense follicular inflammatory infiltrate with abundant eosinophils. Read More

    Facial and extrafacial eosinophilic pustular folliculitis: a clinical and histopathological comparative study.
    Br J Dermatol 2014 May;170(5):1173-6
    Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Pungnapdong Songpagu, Seoul, 138-736, Korea.
    Background: Although more than 300 cases of eosinophilic pustular folliculitis (EPF) have been reported to date, differences in clinicohistopathological findings among affected sites have not yet been evaluated.

    Objectives: To evaluate differences in the clinical and histopathological features of facial and extrafacial EPF.

    Methods: Forty-six patients diagnosed with EPF were classified into those with facial and extrafacial disease according to the affected site. Read More

    Histopathological study of cutaneous manifestations in HIV and AIDS patients.
    Int J Dermatol 2014 Jun 10;53(6):746-51. Epub 2013 Dec 10.
    Department of Pathology, Byramjee Jeejeebhoy Government Medical College, Sassoon General Hospital, Pune, India.
    Objectives: Most human immunodeficiency virus (HIV)-infected patients develop various skin diseases. These skin manifestations not only act as markers but also reflect the patient's underlying immune status. Investigating CD4 counts is costly and not always possible. Read More


    [Verification of the hygienic hypothesis by evaluating the regional incidence of eosinophilic pustular folliculitis].
    J UOEH 2013 Sep;35(3):201-5
    Department of Dermatology, School of Medicine, University of Occupational and Environmental Health, Japan.
    Eosinophilic pustular folliculitis (EPF) is a disorder associated with a high expression of interleukin-5 by T helper 2 cells. Treatment involving T helper 1 (Th1) modulation has been shown to be effective. We report that the occurrence of Bowen's disease in the medical care zone of the University of Occupational and Environmental Health in the Kitakyushu industrial area is more frequent in Yahatahigashi-ku, Yahatanishi-ku, and Wakamatsu-ku than in Tobata-ku, Kokurakita-ku, and Kokuraminamiku. Read More

    Patient characteristics of neonatal eosinophilic pustulosis.
    Pediatr Dermatol 2013 Nov-Dec;30(6):e204-7. Epub 2013 Jul 22.
    Department of Dermatology, Stony Brook University, Stony Brook, New York.
    A 10-week old preterm infant boy presented with a pustular eruption of the face and blood eosinophilia. Histology demonstrated eosinophils without predominant follicular involvement. The lesions healed without intervention within 2 months. Read More

    Transdermal nicotine patches for eosinophilic pustular folliculitis.
    J Dermatol 2013 Sep 27;40(9):711-4. Epub 2013 Jun 27.
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
    We previously reported the clinical effectiveness of transdermal nicotine patches for the treatment of skin disorders with eosinophilic infiltration such as Kimura's disease, erythema nodosum and eosinophilic pustular folliculitis (EPF). We assessed the efficacy and safety of transdermal nicotine patches for EPF. We treated eight patients with EPF with transdermal nicotine patches and evaluated the treatment response by performing overall lesional assessment. Read More

    Evaluation of the Effectiveness of Antibiotics against Eosinophilic Pustular Folliculitis.
    Case Rep Dermatol 2013 May 4;5(2):144-7. Epub 2013 May 4.
    Departments of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
    Eosinophilic pustular folliculitis (EPF) is a chronic intractable pruritic dermatosis. Although indomethacin is generally effective against EPF and considered as a first-line therapy, quite a few patients with indomethacin still suffer from the symptoms. Among other therapeutic options, some antibiotics have been reported to be effective; however, there has been no epidemiological description regarding oral antibiotics use in patients with EPF. Read More

    Indomethacin inhibits eosinophil migration to prostaglandin D2 : therapeutic potential of CRTH2 desensitization for eosinophilic pustular folliculitis.
    Immunology 2013 Sep;140(1):78-86
    Department of Dermatology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.
    Indomethacin is a cyclo-oxygenase inhibitor, and shows therapeutic potential for various eosinophilic skin diseases, particularly eosinophilic pustular folliculitis. One of the unique characteristics of indomethacin is that, unlike other non-steroidal anti-inflammatory drugs, it is a potent agonist of chemoattractant receptor-homologous molecule expressed on T helper type 2 cells (CRTH2), a receptor for prostaglandin D2 (PGD2 ). This study investigated the pharmacological actions of indomethacin on eosinophil migration to clarify the actual mechanisms underlying the therapeutic effects of indomethacin on eosinophilic pustular folliculitis. Read More

    Clinical and histopathological differential diagnosis of eosinophilic pustular folliculitis.
    J Dermatol 2013 Jun 12;40(6):419-23. Epub 2013 Mar 12.
    Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu, Japan.
    Eosinophilic pustular folliculitis (EPF) is an inflammatory disease characterized by repeated pruritic follicular papules and pustules arranged in arcuate plaques, and folliculotropic infiltration of eosinophils. The diagnosis of EPF is occasionally difficult and problematic because EPF may share the clinical appearance and histological findings with other diseases. Moreover, EPF has several clinical subtypes, including the classical type, infantile type and immunosuppression-associated type. Read More

    Vesicles and pustules in the neonate.
    Semin Perinatol 2013 Feb;37(1):8-15
    Children's Hospital of Philadelphia, Philadelphia, PA 19010, USA.
    Vesicles and pustules in the neonate can be due to common or life threatening conditions. Recognizing key clinical features and understanding when and how to workup the various different vesiculopustular eruptions that occur in the neonatal period is vital. A rapid diagnosis of an infectious cause of a neonatal vesiculopustular eruption can be life-saving. Read More

    Eosinophilic pustular folliculitis in infancy: report of a new case.
    Dermatol Online J 2012 Oct 15;18(10). Epub 2012 Oct 15.
    Servicio de Dermatología, Hospital Ramón y Cajal, Madrid, Spain.
    We report a new case of eosinophilic pustular folliculitis in a 23-month-old boy. He presented with a seven-month history of recurrent episodes of pustular lesions on the scalp after having been treated with oral antifungal and topic antibiotics without response. The diagnosis was based on the clinical course and typical histopathological findings. Read More

    Eosinophilic pustular folliculitis: a review of the Japanese published works.
    J Dermatol 2013 Jan 22;40(1):15-20. Epub 2012 Oct 22.
    Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
    Eosinophilic pustular folliculitis (EPF), also known as Ofuji's disease, is an inflammatory dermatosis that was first described in Japan in 1970. More than 300 cases have been reported so far, and 113 Japanese cases have been reported in Japan since 1980. To comprehend the characteristics of Japanese EPF cases, we classified these cases into three types: classic, immunosuppression-associated (IS-EPF), and infancy-associated (I-EPF). Read More

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