163 results match your criteria Eosinophilic Granuloma Thoracic

Pathological features of Brucella spondylitis: A single-center study.

Ann Diagn Pathol 2022 Jun 2;58:151910. Epub 2022 Feb 2.

Department of Spinal Surgery, General Hospital of Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region 750004, China. Electronic address:

Objective: To explore the pathological features of Brucella spondylitis (BS) under the optical microscope, thus providing pathological references for the diagnosis.

Methods: We retrospectively analyzed 70 BS patients (42 males and 28 females, mean age 52.01 ± 10. Read More

View Article and Full-Text PDF

Metachronous Eosinophilic Granuloma of Rib in an Adult Patient.

Cureus 2021 Dec 24;13(12):e20670. Epub 2021 Dec 24.

Thoracic Surgery, Gazi University School of Medicine, Ankara, TUR.

Eosinophilic granuloma (EG) is the unifocal osseous form of Langerhans cell histiocytosis (LCH), which usually affects the skull and long bones. Although it most commonly affects the pediatric age group, it can rarely be seen in adults. Skeletal involvement is common in adult patients, but isolated rib involvement is extremely rare. Read More

View Article and Full-Text PDF
December 2021

First technical report of a pediatric case with thoracic Langerhans cell histiocytosis: Gross total tumor removal, corpectomy, and 360° stabilization via posterolateral approach at a single stage.

J Craniovertebr Junction Spine 2021 Jul-Sep;12(3):236-239. Epub 2021 Sep 8.

Department of Neurosurgery, Ankara University School of Medicine, Ibn-i Sina Hospital, Ankara, Turkey.

Background: Langerhans cell histiocytosis (LCH) is a rare nonmalignant disease characterized by a clonal proliferation of mononuclear cells called Langerhans histiocytes and infiltrates surrounding tissues, mostly self-limiting and usually occurring in the first two decades of life. Vertebral involvement is rare, mostly seen in the thoracic region, and involves the anterior elements of the corpus. In the literature, several treatment options and surgical approaches have been reported concerning the treatment of this disease and surgery. Read More

View Article and Full-Text PDF
September 2021

Posterior Focal Curettage and Spine Stability Reconstruction by Temporary Pedicle Screw Fixation in Children With Collapsed Vertebrae due to Eosinophilic Granuloma.

Global Spine J 2021 Feb 15:2192568220988269. Epub 2021 Feb 15.

Department of Paediatric Orthopaedics, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.

Study Design: Retrospective case series.

Objectives: To evaluate the efficacy of growth-preserving posterior spinal column reconstruction surgery in children with collapsed vertebral eosinophilic granuloma (EG).

Methods: We retrospectively reviewed 15 confirmed cases of vertebral EG who met the inclusion and exclusion criteria from March 2015 to March 2018 in our hospital. Read More

View Article and Full-Text PDF
February 2021

Histiocytosis in the pediatric spine: a clinical and radiographic analysis of 50 patients.

Spine Deform 2021 05 5;9(3):823-831. Epub 2021 Jan 5.

Servicio de Patología Espinal, Hospital de Pediatría Prof. Dr. Juan P. Garrahan, Combate de los Pozos 1881, C1245AAM, Buenos Aires, CABA, Argentina.

Study Design: Descriptive, retrospective. Scientific level of evidence IV.

Objectives: The aim of this study was to evaluate a consecutive case series of 50 pediatric patients with LCH of the spine. Read More

View Article and Full-Text PDF

Nasal polyps in eosinophilic granulomatosis with polyangiitis: Structured histopathology and CD105 expression.

Am J Otolaryngol 2020 Nov - Dec;41(6):102661. Epub 2020 Aug 10.

Department of Neuroscience - DNS, Otolaryngology Section, Padova University, Via Giustiniani 2, 35128 Padova, Italy. Electronic address:

Purpose: Distinguishing the prodromal nasal polyposis of eosinophilic granulomatosis with polyangiitis (EGPA) from chronic rhinosinusitis with nasal polyps (CRSwNP) is a challenge for rhinologists and rheumatologists. It has recently been reported that angiogenesis and CD105 expressed on vascular endothelial cells could have a role in the pathogenesis and development of nasal polyps. This exploratory study examined the structured histopathology of nasal polyps in patients with EGPA and CRSwNP, comparing CD105 expression in their nasal tissue with that of a control group with no chronic sinonasal inflammation. Read More

View Article and Full-Text PDF
December 2020

Long-term Follow-up of Eosinophilic Granulomas of the Axial and Appendicular Skeleton Managed With Biopsy Alone.

J Pediatr Orthop 2020 Nov/Dec;40(10):615-622

Department of Orthopaedics and Traumatology, Koc University Hospital, Istanbul, Turkey.

Background: This study aimed to evaluate the long-term clinical and radiologic follow-up results of eosinophilic granulomas (EGs) of the axial and appendicular skeleton managed with biopsy alone.

Methods: Fifty-five patients with unifocal osseous EGs of the axial and appendicular skeleton were followed after biopsy. Patients were divided into 2 groups on the basis of localization of the lesions. Read More

View Article and Full-Text PDF

Eosinophilic bronchitis, eosinophilic granuloma, and eosinophilic bronchopneumopathy in 75 dogs (2006-2016).

J Vet Intern Med 2019 Sep 29;33(5):2217-2226. Epub 2019 Aug 29.

Department of Pathology, Microbiology and Immunology, The University of California School of Veterinary Medicine, Davis, California.

Background: Eosinophilic lung disease is a poorly understood inflammatory airway disease that results in substantial morbidity.

Objective: To describe clinical findings in dogs with eosinophilic lung disease defined on the basis of radiographic, bronchoscopic, and bronchoalveolar lavage fluid (BAL) analysis. Categories included eosinophilic bronchitis (EB), eosinophilic granuloma (EG), and eosinophilic bronchopneumopathy (EBP). Read More

View Article and Full-Text PDF
September 2019

Lung Transplantation in Hungary From Cardiac Surgeons' Perspective.

Transplant Proc 2019 May;51(4):1263-1267

Department of Thoracic Surgery, Semmelweis University, Budapest, Hungary; Department of Thoracic Surgery, National Institute of Oncology, Budapest, Hungary.

Thoracic organ transplantation made a fresh start in Hungary with the first double lung transplant in December 2015. This major leap in Hungarian transplantation was preceded by almost 10 years of preparation, new infrastructure development, and structural changes not only at the organizational level but in human resources as well. In the following years, until recently, altogether 47 lung transplants were performed on 24 men and 23 women. Read More

View Article and Full-Text PDF

Eosinophilic granuloma of the spine involving C1 and pulmonary infiltration in young children - Presentation of two cases with a follow-up over 10 years including review of the literature.

J Orthop 2018 Sep 16;15(3):808-811. Epub 2018 Aug 16.

Department of Orthopedic Surgery, University of Ulm, Oberer Eselsberg 45, 89081, Ulm, Germany.

Objectives: The incidence of spinal eosinophilic granuloma in children is low.

Methods: Clinical case presentation of two children (♀ 18 months old, ♂ 16 months old) complaining of acute torticollis. Follow-up period was 11 years in the female patient and 13 years in the male patient. Read More

View Article and Full-Text PDF
September 2018

Spontaneous and complete regeneration of a vertebra plana after surgical curettage of an eosinophilic granuloma.

Eur Spine J 2017 05 30;26(Suppl 1):225-228. Epub 2017 Mar 30.

Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.

Purpose: The eosinophilic granuloma is a unifocal or multifocal Langerhans cell histiocytosis characterized by an expanding proliferation of Langerhans cells in bones. Skeletal LCH is a rare condition, and vertebral regeneration in cases of vertebral body collapse is even rarer. We report the case of a girl with spontaneous complete healing. Read More

View Article and Full-Text PDF

Management of eosinophilic granuloma in pediatric patients: surgical intervention and surgery combined with postoperative radiotherapy and/or chemotherapy.

Childs Nerv Syst 2017 Apr 28;33(4):583-593. Epub 2017 Feb 28.

Department of Spine Surgery, Xiangya Hospital of Central South University, Xiangya Road 87, Changsha, Hunan Province, 410008, China.

Background: Eosinophilic granuloma (EG) of spine in pediatric patients presents kinds of clinical manifestation and a difficult management scenario. The choice of treatment, issues of surgical intervention versus conservative treatment, combination therapy or single treatment, all these factors, including neurological deficits, spinal stability, long-term complications, and continued skeletal growth, must be considered.

Methods: From 2008 to the 2015, 31 pediatric patients of spinal EG were retrospectively reviewed. Read More

View Article and Full-Text PDF

Histologic Findings of Severe/Therapy-Resistant Asthma From Video-assisted Thoracoscopic Surgery Biopsies.

Am J Surg Pathol 2017 Feb;41(2):182-188

Departments of *Pathology ‡Cardiothoracic Surgery, University of Pittsburgh Medical Center †Department of Medicine, Pulmonary Allergy and Critical Care Medicine Division, University of Pittsburgh Asthma Institute, University of Pittsburgh Medical Center, Pittsburgh, PA.

The histologic changes occurring in severe/therapy-resistant asthma (SA) as defined by the European Respiratory Society/American Thoracic Society guidelines, particularly at the level of the distal airways are unknown. This study describes the clinical, radiologic, and histologic characteristics of 29 SA patients who underwent video-assisted thoracoscopic surgery lung biopsy. Pathologic observations were correlated with clinical features, especially the presence of autoimmune disease (AID) (15/29, 51. Read More

View Article and Full-Text PDF
February 2017

Rosai-Dorfman disease of vertebra: Case report and literature review.

Turk J Pediatr 2016 ;58(5):566-571

Pediatric Clinic, Clinical Centre Kragujevac; University of Kragujevac, Kragujevac, Serbia.

Rosai-Dorfman disease is a rare benign histiocytic disorder that arises predominantly in lymph nodes with fever and malaise, but can affect various organs, with or without lymphadenopathy. Solitary extranodal skeletal lesions are extremely rare. Herein, we describe a case of isolated disease of thoracic spine, with vertebral body fracture. Read More

View Article and Full-Text PDF
September 2017

PET/CT positive in a case with eosinophilic granuloma.

Tuberk Toraks 2015 Sep;63(3):207-9

Department of Chest Diseases, Faculty of Medicine, Dicle University, Diyarbakir, Turkey.

View Article and Full-Text PDF
September 2015

Thoracic Bone Tumors Every Radiologist Should Know.

Curr Probl Diagn Radiol 2016 Jan-Feb;45(1):71-9. Epub 2015 Jun 15.

Department of Radiology, University of Florida-College of Medicine, Gainesville, FL. Electronic address:

The thoracic cage provides the structural support that makes respiration possible, provides protection to vital organs such as the lungs, heart, liver, and spleen, and serves as an anchor point for the upper extremities. Neoplasms of the bony thorax are not an uncommon incidental finding at both radiography and cross-sectional imaging. Some tumors have a characteristic appearance and it is important that an accurate differential diagnosis be provided. Read More

View Article and Full-Text PDF
September 2016

Sternal tumor resection and reconstruction with titanium mesh: a preliminary study.

Orthop Surg 2015 May;7(2):155-60

Department of Orthopaedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Objective: To explore the clinical efficacy and complications of treating sternal tumors by resection and titanium mesh thoracic reconstruction.

Methods: This retrospective analysis of eight patients with sternal tumors treated in the Department of Orthopedic Surgery at the First Affiliated Hospital of Zhengzhou University from January 2008 to June 2012 included five men and three women aged 37-66 years (mean, 50.4 years). Read More

View Article and Full-Text PDF

Sarcocystis fayeri-Induced Granulomatous and Eosinophilic Myositis in 2 Related Horses.

Vet Pathol 2015 Nov 8;52(6):1191-4. Epub 2015 May 8.

Department of Veterinary Clinical Sciences, Oklahoma State University, Stillwater, OK, USA

This report describes 2 genetically related paint mares, case Nos. 1 and 2, presented to the Oklahoma State University Boren Veterinary Medical Teaching Hospital for chronic weight loss and abnormal gait, respectively. Notable findings in both cases included marked persistent eosinophilia and multiple intramuscular lateral thoracic masses. Read More

View Article and Full-Text PDF
November 2015

Rib tumors: a 15-year experience.

Gen Thorac Cardiovasc Surg 2014 Jul 11;62(7):434-40. Epub 2014 Mar 11.

Thoracic Surgery Department, 401 General Army Hospital, Athens, Greece,

Objective: A retrospective study of rib tumors was conducted to review their clinical, radiological, and pathological features, the difficulties in differentiating benign from malignant tumors, as well as the early and long-term results of surgical management.

Methods: All patients with rib lesions evaluated by the Thoracic Surgery Department from 1998 to 2012 were studied. The patient's age, sex, symptoms, radiologic evaluation, surgical procedure, pathologic diagnosis and follow-up were assessed. Read More

View Article and Full-Text PDF

False Positive F-18 FDG PET/CT of Skeletal Metastasis Due to Solitary Eosinophilic Granuloma.

Mol Imaging Radionucl Ther 2013 Dec 10;22(3):103-5. Epub 2013 Dec 10.

Nepean Hospital, Oncology Department, Penrith, Australia.

Unlabelled: A 31 year old female with a 3 month history of focal right mid posterior thoracic pain, and solitary lytic lesion in the right 7th rib posteriorly on bone scan (SPECT/CT) was referred for PET/CT to identify alternate site for biopsy in suspected malignancy. The patient had no significant past medical history and was afebrile with mildly elevated inflammatory markers. A solitary intensely FDG avid focus was demonstrated localised to a well-defined lytic lesion with partial cortical erosion on the posterior aspect of the right 7th rib. Read More

View Article and Full-Text PDF
December 2013

Thoracic paravertebral nerve block as the sole anesthetic for an open biopsy of a large anterior mediastinal mass.

J Cardiothorac Vasc Anesth 2014 Aug 12;28(4):1032-9. Epub 2013 Sep 12.

Department of Pulmonology, University Hospital Centre Zagreb, Jordanovac 104, Zagreb, Croatia.

View Article and Full-Text PDF

Pedicle screw implantation in the thoracic and lumbar spine of 1-4-year-old children: evaluating the safety and accuracy by a computer tomography follow-up.

J Spinal Disord Tech 2013 Apr;26(2):E46-52

Department of Spine Surgery, The Second Xiangya Hospital of Central South University, Changsha, Hunan, PR China.

Study Design: This was a retrospective clinical study.

Objective: To evaluate the safety and accuracy of pedicle screw placement in very young children and to observe its influence on vertebral and spinal canal growth.

Summary Of Background Data: Although widely used, it is not known if pedicle screw fixation is safe and effective in very young children. Read More

View Article and Full-Text PDF

Langerhans cell histiocytosis case with dense metaphyseal band sign.

Pediatr Int 2013 Feb;55(1):96-8

Departments of Pediatric Orthopedics Pediatric Radiology Pediatrics, Jichi Children's Medical Center Tochigi, Shimotsuke, Japan.

Eosinophilic granuloma, a type of Langerhans cell histiocytosis, exhibits a classic vertebral collapse, which is called vertebra plana (Calve's disease) and it manifests as a solitary bony lesion. Vertebra plana can cause severe pain in patients. Bisphosphonates (clodronate, pamidronate and zoledronic acid) have been recently used to treat osteolytic bone lesions of LCH. Read More

View Article and Full-Text PDF
February 2013

Eosinophilic pulmonary granulomatosis in a young dog with prolonged remission after treatment.

J Small Anim Pract 2013 Jan 12;54(1):40-3. Epub 2012 Nov 12.

Small Animal Clinic Vihtivet, Säntikuja 2, 03100, Nummela, Finland.

A two-year-old Jack Russell terrier was presented for evaluation of chronic cough and exercise intolerance. Previous treatment with antibiotics and glucocorticoids had only partially ameliorated the clinical signs. During investigation, hypoxaemia, peripheral eosinophilia and an eosinophilic bronchoalveolar lavage fluid were noted. Read More

View Article and Full-Text PDF
January 2013

Chickenpox-related pulmonary granulomas in immunocompetent adults: clinicopathologic and molecular features of an underrated occurrence.

Am J Surg Pathol 2012 Oct;36(10):1497-502

Section of Pathologic Anatomy, Azienda Ospedaliero-Universitaria Policlinico, Modena, Italy.

Pulmonary granulomas represent a common inflammatory reaction to several lung infective or noninfective diseases. However, little is known about the histology and clinical presentation of chickenpox-related granulomas in immunocompetent subjects. We collected a series of 8 adult patients (mean age, 40 y; range, 33 to 53 y) with several bilateral pulmonary granulomas incidentally discovered after imaging studies. Read More

View Article and Full-Text PDF
October 2012

Surgical resection of sternal tumors and reconstruction with titanium mesh.

Chin Med Sci J 2011 Dec;26(4):237-40

Department of Thoracic Surgery, Peking Union Medical College Hospital, Chinese.

Objective: To evaluate the use of titanium mesh reconstruction after sternal tumor resection.

Methods: From January 2007 to January 2011, 14 patients with sternal tumors were admitted into Peking Union Medical Hospital. The clinical characteristics, surgical resection, and technique of reconstruction were reviewed. Read More

View Article and Full-Text PDF
December 2011

[Subcutaneous mass as initial manifestation of an osteolytic metastasis].

Dtsch Med Wochenschr 2011 Oct 28;136(40):2040-2. Epub 2011 Sep 28.

Diagnostische und interventionelle Radiologie, HELIOS-Klinikum Wuppertal, Universitätsklinik Witten/Herdecke.

History And Clinical Findings: A 69-year-old woman was admitted for evaluation of a left occipital subcutaneous tumour which had grown during the preceding eight weeks from 2 × 2 cm to 4 × 4 cm.

Investigations: Sonography revealed a pressure-sensitive subcutaneous mass with osteolytic destruction in the occipital bone. Cranial magnetic resonance imaging confirmed the osteolytic lesion. Read More

View Article and Full-Text PDF
October 2011

[Eosinophilic angiocentric fibrosis and granuloma facial with extra facial presentation, the same pathology?].

Ann Pathol 2011 Jun 20;31(3):138-41. Epub 2011 May 20.

Service d'anatomie et de cytopathologie, centre hospitalier Lyon-Sud, 165, chemin du Grand-Revoyet, 69495 Pierre-Bénite, France.

Eosinophilic angiocentric fibrosis is a rare fibro inflammatory lesion of unknown etiology which occurs usually in the upper respiratory tract mucosa of middle-aged adults. The histologic features show an eosinophilic vasculitis and an angiocentric fibrosis with onion-skin pattern. Firstly described as a mucosal variant of the granuloma facial, which is a rare cutaneous vasculitis with eosinophils, it is considerated by some authors as separated entities. Read More

View Article and Full-Text PDF