3,235 results match your criteria Eosinophilic Granuloma Histiocytosis X


Pulmonary Langerhans Cell Histiocytosis Associated with Bronchogenic Carcinoma.

Cureus 2020 Jan 12;12(1):e6634. Epub 2020 Jan 12.

Internal Medicine: Pulmonology/Critical Care, Charleston Area Medical Center, Charleston, USA.

Pulmonary Langerhans cell histiocytosis (PLCH, pulmonary eosinophilic granuloma) is a rare disease of clonal dendritic cells that primarily affects adults who smoke cigarettes. PLCH association with other malignancies is rarely reported. Herein, an unusual case of PLCH is presented with synchronous lung adenocarcinoma. Read More

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http://dx.doi.org/10.7759/cureus.6634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011584PMC
January 2020

Langerhans Cell Histiocytosis in an Adult with Oral Cavity Involvement: Posing a Diagnostic Challenge.

Contemp Clin Dent 2019 Jan-Mar;10(1):154-157

Department of Oral and Maxillofacial Pathology, Guru Nanak Institute of Dental Sciences and Research, Kolkata, West Bengal, India.

Langerhans cell histiocytosis (LCH) is a rare hematological disorder characterized by local or generalized, uncontrolled proliferation and infiltration of Langerhans type of histiocytic cells. It represents a spectrum of clinicopathologic disorders, ranging from a highly aggressive and frequently fatal multisystem disease to an easily cured solitary lesion of bone. Involvement of children and the younger age group is more common than the adults. Read More

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http://dx.doi.org/10.4103/ccd.ccd_432_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974994PMC
February 2020

A Case of Multi-System Langerhans Cell Histiocytosis with Local Invasion of the Orbital Apex.

Case Rep Ophthalmol 2019 Sep-Dec;10(3):319-326. Epub 2019 Sep 19.

Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.

Langerhans cell histiocytosis (LCH) is characterised by tissue destruction caused by the abnormal proliferation of pathogenic dendritic cells. We report a rare case of multi-system LCH with local invasion of the orbital apex. A 56-year-old woman suffered from a decrease of visual acuity in the left eye caused by central scotoma and the limitation of eye movement in all directions. Read More

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http://dx.doi.org/10.1159/000502946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873077PMC
September 2019

Traumatic ulcerative granuloma with stromal eosinophilia - clinical case report, literature review, and differential diagnosis.

World J Surg Oncol 2019 Nov 9;17(1):184. Epub 2019 Nov 9.

Department of Oral and Craniomaxillofacial Surgery, University Hospital Basel, Spitalstrasse 21, CH-4031, Basel, Switzerland.

Background: Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is a rare self-limiting condition of the oral mucosa. The lesion manifests as an isolated ulcer that can be either asymptomatic or associated with mild to severe pain, and in most cases, it affects the tongue. TUGSE lesions may mimic malignancy such as squamous cell carcinoma, CD30 positive lymphoproliferative disorder, or infectious diseases such as primary syphilis, tuberculosis, or Epstein-Barr virus mucocutaneous ulcer. Read More

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http://dx.doi.org/10.1186/s12957-019-1736-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842515PMC
November 2019

Outcome of Surgery as Sole Treatment of Eosinophilic Granuloma of Jaws.

J Dent (Shiraz) 2019 Sep;20(3):210-214

Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Ardabil University of Medical Sciences, Ardabil, Iran.

Langerhans cell histiocytosis (LCH) is characterized by the congregation of proliferating langerhans cells (LC). Langerhans cells are a part of dendritic cell system of primary immune response that is responsible for presenting antigen to lymphocytes. Being a rare disease, the total incidence of LCH is reported to be 1 in 2 million people. Read More

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http://dx.doi.org/10.30476/DENTJODS.2019.44903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732173PMC
September 2019
1 Read

Langerhans Cell Histiocytosis of the Skull.

Ear Nose Throat J 2019 Sep 26:145561319869605. Epub 2019 Sep 26.

Department of Otolaryngology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA.

This is a case of a pediatric male who presented with a postauricular mass and pain. Computed tomography and magnetic resonance imaging suggested a diagnosis of Langerhans cell histiocytosis. Characteristic imaging findings and initial workup for Langerhans cell histiocytosis are described. Read More

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http://dx.doi.org/10.1177/0145561319869605DOI Listing
September 2019
2 Reads

[Langerhans cell histiocytosis revealed by a temporomandibular joint disorder: Report of a case and review of the craniofacial expressions].

Rev Med Interne 2020 Jan 29;41(1):50-53. Epub 2019 Aug 29.

Service de chirurgie maxillo-faciale et stomatologie, centre hospitalo-universitaire de Rouen, 1, rue de Germont, 76000 Rouen, France; Laboratoire d'anatomie, faculté de médecine de Rouen, 22, boulevard Gambetta, 76000 Rouen, France; Institut national de la santé et de la recherche médicale (Inserm), LIMICS UMR-1142, 76000 Rouen, France. Electronic address:

Introduction: Langerhans cell histiocytosis (HL) is a rare disease that can affect all tissues. Oral manifestations such as mucosal ulcer and tooth mobility are often the first signs of the disease. We report a rare case of mandibular condyle unifocal HL mimicking a temporomandibular joint disorder. Read More

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http://dx.doi.org/10.1016/j.revmed.2019.08.005DOI Listing
January 2020
1 Read

Eosinophilic bronchitis, eosinophilic granuloma, and eosinophilic bronchopneumopathy in 75 dogs (2006-2016).

J Vet Intern Med 2019 Sep 29;33(5):2217-2226. Epub 2019 Aug 29.

Department of Pathology, Microbiology and Immunology, The University of California School of Veterinary Medicine, Davis, California.

Background: Eosinophilic lung disease is a poorly understood inflammatory airway disease that results in substantial morbidity.

Objective: To describe clinical findings in dogs with eosinophilic lung disease defined on the basis of radiographic, bronchoscopic, and bronchoalveolar lavage fluid (BAL) analysis. Categories included eosinophilic bronchitis (EB), eosinophilic granuloma (EG), and eosinophilic bronchopneumopathy (EBP). Read More

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http://dx.doi.org/10.1111/jvim.15605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766508PMC
September 2019
3 Reads

Diagnosis and treatment of Langerhans Cell Histiocytosis with bone lesion in pediatric patient: A case report.

Ann Med Surg (Lond) 2019 Sep 2;45:102-109. Epub 2019 Aug 2.

Department of Orthopaedic and Traumatology, Dr.Cipto Mangunkusumo General Hospital/Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.

Background: Langerhans cell histiocytosis (LCH) is a rare group of disorders without a well understood etiology. Known formerly as histiocytosis X, the disease has a wide spectrum of clinical presentations, including eosinophilic granuloma (solitary bone lesion), diabetes insipidus, and exophthalmos. Many of these patients initially present to orthopaedic surgeons, and misdiagnosis is frequent. Read More

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http://dx.doi.org/10.1016/j.amsu.2019.07.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702438PMC
September 2019

Myopericarditis as a presentation of eosinophilic granulomatosus with polyangiitis (EGPA).

BMJ Case Rep 2019 Aug 15;12(8). Epub 2019 Aug 15.

Department of Cardiology, Aintree University Hospitals NHS Foundation Trust, Liverpool, UK.

A 60-year-old woman was admitted to the hospital with worsening dyspnoea, cough and chest pain. This was on a background of weight loss, decreased appetite, mononeuritis multiplex, chronic eosinophilia and a single episode of a non-blanching rash. Investigations demonstrated a raised troponin and ischaemic changes on ECG, and she was therefore initially treated for a presumed myocardial infarction. Read More

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http://dx.doi.org/10.1136/bcr-2019-230593DOI Listing
August 2019
4 Reads

New perspectives in eosinophilic granulomatosis with polyangiitis (EGPA): report of the first meeting of the European EGPA Study Group.

Intern Emerg Med 2019 11 6;14(8):1193-1197. Epub 2019 Aug 6.

SOC Nefrologia E Dialisi, Azienda Ospedaliero-Universitaria Meyer, e Dipartimento Di Scienze Biomediche, Sperimentali e Cliniche "Mario Serio", Università Di Firenze, Viale Pieraccini 6, 50139, Florence, Italy.

The European Eosinophilic Granulomatosis with Polyangiitis (EGPA) study group first gathered in Firenze in December 2018. The discussion was centred around the clinical and therapeutic needs in EGPA which still remain unmet. Indeed, EGPA is a puzzling and rare disease which shares clinical features with other anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAVs) and hypereosinophilic syndromes (HESs). Read More

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http://dx.doi.org/10.1007/s11739-019-02166-5DOI Listing
November 2019
1 Read

Incidence of cutaneous habronemosis in Manipuri ponies in India.

Vet Parasitol Reg Stud Reports 2019 08 24;17:100295. Epub 2019 Apr 24.

Department of Veterinary Parasitology, College of Veterinary Sciences and Animal Husbandry, Central Agricultural University, Selesih, Aizawl, Mizoram, India.

Information pertaining to parasitic fauna and parasitic diseases in Manipuri ponies in India is not available. Moreover, no systematic studies have been undertaken on cutaneous habronemosis in Manipuri ponies which is a common skin problem of Manipuri ponies as reported by pony owners. Keeping in the view of the importance of parasitic infections in veterinary health coverage particularly in Manipuri ponies, the present study was planned. Read More

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http://dx.doi.org/10.1016/j.vprsr.2019.100295DOI Listing

Angiomatoid Fibrous Histiocytoma Mimicking Eosinophilic Granuloma in a Pediatric Patient.

World Neurosurg 2019 Sep 21;129:345-348. Epub 2019 Jun 21.

Department of Radiology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.

Background: Angiomatoid fibrous histiocytoma (AFH) is a rare low-grade malignant tumor mainly occurring in soft tissues, and its incidence in the bones is extremely rare. Although most of the existing reports focus on the pathological features of AFH, only a few describe its imaging features. To our knowledge, this is the first case of AFH in the skull, and it is distinguished from eosinophilic granuloma based on imaging results. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750193165
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http://dx.doi.org/10.1016/j.wneu.2019.06.102DOI Listing
September 2019
3 Reads

Clinicopathological Features, Risk Factors and Predispositions, and Response to Treatment of Eosinophilic Oral Disease in 24 Dogs (2000-2016).

J Vet Dent 2019 Mar;36(1):25-31

4 Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.

The objectives of this study were to retrospectively describe clinicopathological features of eosinophilic oral disease in dogs, to identify possible risk factors or predispositions to the condition, and to report overall treatment response. Canine medical records from a veterinary teaching hospital and private referral practice over a 17-year period were reviewed for a diagnosis of eosinophilic oral disease. Twenty-four dogs with 26 lesions met the inclusion criteria. Read More

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http://dx.doi.org/10.1177/0898756419834785DOI Listing
March 2019
6 Reads

Eosinophilic Granulomatosis With Polyangiitis: Histopathological Confirmation Despite Negative Serology.

Am J Med 2019 10 14;132(10):e741-e743. Epub 2019 May 14.

Department of Dermatology, Stanford University School of Medicine, Redwood City, Calif; Department of Pathology, Stanford University School of Medicine, Stanford, Calif. Electronic address:

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http://dx.doi.org/10.1016/j.amjmed.2019.04.032DOI Listing
October 2019
15 Reads

Incidence and radiological pattern of eosinophilic granuloma: a retrospective study in a Chinese tertiary hospital.

J Orthop Surg Res 2019 May 9;14(1):123. Epub 2019 May 9.

Department of Radiology and Functional and Molecular Imaging Key Lab of Shaanxi Province, Tangdu Hospital, Fourth Military Medical University (Air Force Medical University), 569 Xinsi Road, Xi'an, 710038, Shaanxi, People's Republic of China.

Background: The incidence and radiological patterns of eosinophilic granuloma (EG) in China is not clear. We described the incidence, presentation, and imaging characteristics of Chinese EG patients in a tertiary hospital.

Methods: A retrospective chart review was performed from January 2004 to October 2017 at a single tertiary general hospital. Read More

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http://dx.doi.org/10.1186/s13018-019-1158-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507022PMC
May 2019
2 Reads
1.577 Impact Factor

Cone Beam CT study of a case of eosinophilic granuloma of the mandible in a young patient.

BMJ Case Rep 2019 May 5;12(5). Epub 2019 May 5.

Diagnostic and Interventional Radiology, University of Pisa, Pisa, Italy.

Eosinophilic granuloma (EG) is a rare bony disease deriving from abnormal proliferation of histiocytes, and is the most common form of presentation of Langerhans cell histiocytosis. EG predominantly affects the axial skeleton. However, when localised in the head and neck district, mandibular lesions account for the majority of cases. Read More

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http://dx.doi.org/10.1136/bcr-2018-228455DOI Listing
May 2019
7 Reads

Langerhans cell histiocytosis presenting as eosinophilic granuloma of the bilateral forearms in an 8-year-old girl: a case report.

J Med Case Rep 2019 Mar 19;13(1):67. Epub 2019 Mar 19.

Department of Paediatric Surgery, University Hospital of Hassan II, Fez, Morocco.

Background: Langerhans cell histiocytosis previously known as histiocytosis X is a rare disease of children and young adults with a very broad clinical spectrum. In children, its annual incidence is estimated between 0.2-0. Read More

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http://dx.doi.org/10.1186/s13256-019-2011-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423802PMC
March 2019
9 Reads

Eosinophilic Granuloma of the Cervical Spine in Adults: A Review.

World Neurosurg 2019 05 13;125:301-311. Epub 2019 Feb 13.

Department of Orthodontics, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal, India.

Objective: Spinal eosinophilic granulomas (EGs) are uncommon tumors, constituting <1% of all bone tumors. They are mostly seen in the pediatric age group, whereas adult onset is rare. The cervical spine is an infrequent location for EG. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.230DOI Listing
May 2019
8 Reads

Eosinophilic Granuloma of Mandible: A Diagnostic Challenge.

Kathmandu Univ Med J (KUMJ) 2018 Apr-Jun;16(62):201-203

Department of Oral Surgery, Peoples Dental College, Shorakhutte, Kathmandu, Nepal.

Eosinophilic Granuloma is the mildest and localized form of Langerhans Cell Histiocytosis and is characterized by clonal proliferation of Langerhans cells. It is a rare disease, accounting for less than 1% of all the osseous neoplasms. It has predilection for the axial skeleton and incidence in jaws is just 7. Read More

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March 2019
8 Reads

[Histiocitosis de Langerhans en el cráneo. Informe de un caso].

Cir Cir 2019 ;87(1):96-100

Delegación Baja California. Instituto Mexicano del Seguro Social, Baja California, México.

Background: Langerhans cell histiocytosis is a rare disease in the adult, predominates in the pediatric age and is more common in men than in women. The sites of greater affection are the long bones, followed by the bones of the skull. Patients usually have symptoms related to the site of affection, usually polyostotic lesions, monostotic lesions occur less frequently. Read More

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http://dx.doi.org/10.24875/CIRU.18000330DOI Listing
August 2019
7 Reads

Langerhans cell histiocytosis in adults is associated with a high prevalence of hematologic and solid malignancies.

Cancer Med 2019 01 30;8(1):58-66. Epub 2018 Dec 30.

Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.

Background: Langerhans cell histiocytosis (LCH) is a rare disorder of histiocyte proliferation. Previous case studies suggest a higher prevalence of hematologic and solid malignancies among LCH patients, possibly due to treatment with tumorigenic agents such as etoposide. We report the first large, single-institution experience of adult LCH patients with additional malignancies to study the characteristics of these patients. Read More

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http://dx.doi.org/10.1002/cam4.1844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346231PMC
January 2019
10 Reads

Evaluation of clinical benefit from treatment with mepolizumab for patients with eosinophilic granulomatosis with polyangiitis.

J Allergy Clin Immunol 2019 06 19;143(6):2170-2177. Epub 2018 Dec 19.

Department of Medicine, National Jewish Health, Denver, Colo. Electronic address:

Background: In a recent phase III trial (NCT02020889) 53% of mepolizumab-treated versus 19% of placebo-treated patients with eosinophilic granulomatosis with polyangiitis (EGPA) achieved protocol-defined remission.

Objective: We sought to investigate post hoc the clinical benefit of mepolizumab in patients with EGPA using a comprehensive definition of benefit encompassing remission, oral glucocorticoid (OGC) dose reduction, and EGPA relapses.

Methods: The randomized, placebo-controlled, double-blind, parallel-group trial recruited patients with relapsing/refractory EGPA receiving stable OGCs (prednisolone/prednisone, ≥7. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183278
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http://dx.doi.org/10.1016/j.jaci.2018.11.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254609PMC
June 2019
43 Reads

Multidisciplinary rehabilitation of eosinophilic granuloma with bone graft surgery and a modified implant-supported hybrid prosthesis: A case report with a 6-year follow-up.

Spec Care Dentist 2019 Jan 15;39(1):45-50. Epub 2018 Nov 15.

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Gazi University, Ankara, Turkey.

Eosinophilic granuloma is the most common form of Langerhans cell histiocytosis and corresponds with bone lesions characterized by pain, rapid growth, and high tendency of recurrence after inadequate curettage. It is a rare disease that is difficult to diagnose clinically and radiographically because it mimics other odontogenic cysts and tumors. In this report, the reconstruction of an osseous defect with an iliac graft and a modified implant-supported hybrid prosthesis after surgical excision of an eosinophilic granuloma in the mandible of a 27-year-old male patient was described. Read More

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http://dx.doi.org/10.1111/scd.12345DOI Listing
January 2019
19 Reads

Common Tumors and Tumor-like Lesions of the Shoulder.

J Am Acad Orthop Surg 2019 Apr;27(7):236-245

From the Department of Orthopaedics (Dr. Lee and Dr. Hills) and the Department of Radiology (Dr. Jordanov), Vanderbilt University Medical Center, Nashville, TN, and the OrthoSports Associates (Dr. Jaffe), Birmingham, AL.

Shoulder lesions range from tumor-like lesions such as simple bone cysts to aggressive high-grade sarcomas. The clinical presentation is often nonspecific with shoulder pain as the primary complaint, which may lead to a delayed or missed diagnosis. Delayed diagnosis or a poorly planned biopsy of a malignant shoulder lesion can have a detrimental effect on the patient's prognosis and treatment options. Read More

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http://Insights.ovid.com/crossref?an=00124635-900000000-9952
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http://dx.doi.org/10.5435/JAAOS-D-17-00449DOI Listing
April 2019
12 Reads

Serum periostin as a biomarker in eosinophilic granulomatosis with polyangiitis.

PLoS One 2018 11;13(10):e0205768. Epub 2018 Oct 11.

Division of Rheumatology and the Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

Objective: Identification of a biomarker for disease activity in eosinophilic granulomatosis with polyangiitis (EGPA; Churg-Strauss) remains an unmet need. This study examined the value of serum periostin, a marker of type 2 inflammation, as a measure of disease activity in patients with EGPA.

Methods: Participants enrolled in a multicenter, prospective cohort of patients with EGPA were included in this study if they had disease activity (defined as Birmingham Vasculitis Activity Score [BVAS] > 0) during follow-up. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205768PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181402PMC
March 2019
41 Reads
3.230 Impact Factor

[Histiocitosis de células de Langerhans con compromiso vertebral].

Bol Med Hosp Infant Mex 2018 ;75(5):309-312

Hospital San Rafael de Tunja, Boyacá. Colombia.

Introducción: La histiocitosis de células de Langerhans (HCL) es un trastorno histiocítico raro y su incidencia exacta se mantiene desconocida; se ha diagnosticado en todos los grupos de edad, pero es más común en los primeros 3 años de vida. Se caracteriza por lesiones únicas o múltiples de tipo osteolítico causadas por proliferación clonal de células histológicamente similares a las células de Langerhans; su presentación clínica es heterogénea.

Caso Clínico: Presentamos el caso de una paciente de sexo femenino de 7 años, con dificultad para la marcha y debilidad progresiva en los miembros inferiores de 5 días de evolución. Read More

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http://dx.doi.org/10.24875/BMHIM.M18000024DOI Listing
October 2019
13 Reads

[A case of multiple cerebral hemorrhage caused by sudden increase of eosinophil in a patient with eosinophilic granulomatosis with polyangiitis].

Rinsho Shinkeigaku 2018 Sep 31;58(9):565-569. Epub 2018 Aug 31.

Department of Neurology, Nagaoka Red Cross Hospital.

A 42-year-old woman with bronchial asthma was admitted to our hospital due to sensory dominant mononeuritis multiplex lasting for more than 6 months. At that time, her eosinophil count was 761/μl and her sural nerve biopsy showed no findings suggestive of vasculitis. Four months later, she experienced sudden convulsions and right hemiparesis due to left lobular parietal subcortical hemorrhage, when her eosinophil count was elevated to 3,257/μl. Read More

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http://dx.doi.org/10.5692/clinicalneurol.cn-001188DOI Listing
September 2018
12 Reads

An Unusual Presentation of Langerhans Cell Histiocytosis.

J Coll Physicians Surg Pak 2018 Sep;28(9):S172-S173

Department of Histopathology, Shifa International Hospital, Islamabad.

Langerhans cell histiocytosis (LCH) is a rare entity formerly known as eosinophilic granuloma. It is characterised by clonal multiplication of langerhans cells (LCs) that can occur anywhere in the body, especially in connective tissue of skin, lymph nodes and bone. Although rare, the disorder frequently affects children. Read More

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https://www.jcpsp.pk/data/view.php?id=356&type=pdf&j
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http://dx.doi.org/10.29271/jcpsp.2018.09.S172DOI Listing
September 2018
43 Reads

Eosinophilic granulomatosis with polyangiitis mimicking peripheral T-cell lymphoma, not otherwise specified.

Scand J Rheumatol 2019 03 28;48(2):171-172. Epub 2018 Aug 28.

a Department of Internal Medicine , Tomakomai City Hospital , Tomakomai , Japan.

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https://www.tandfonline.com/doi/full/10.1080/03009742.2018.1
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http://dx.doi.org/10.1080/03009742.2018.1493746DOI Listing
March 2019
32 Reads

Langerhans cell histiocytosis of the orbit: A study of eight cases.

Oman J Ophthalmol 2018 May-Aug;11(2):134-139

Ocular Oncology Service, The Operation Eyesight Universal Institute for Eye Cancer, L V Prasad Eye Institute, Hyderabad, Telangana, India.

Background: Langerhans cell histiocytosis (LCH) of the orbit is a rare clinical entity with a diagnostic and therapeutic dilemma.

Materials And Methods: This was a retrospective study of eight patients with orbital LCH.

Results: All eight patients in our series were male, and the mean age at presentation was 8 years (median 6 years; range, 7 months-23 years). Read More

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http://dx.doi.org/10.4103/ojo.OJO_226_2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991070PMC
June 2018
47 Reads

Image Gallery: Concomitant eosinophilic angiocentric fibrosis and granuloma faciale.

Br J Dermatol 2018 06;178(6):e395

Department of Dermatology, Peking Union Medical College Hospital, Dongcheng District, Beijing, 100730,, China.

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http://dx.doi.org/10.1111/bjd.16574DOI Listing
June 2018
4 Reads

Oral manifestation of Langerhans cell histiocytosis: a case report.

BMC Oral Health 2018 06 8;18(1):106. Epub 2018 Jun 8.

Clinic of Cranio-Maxillofacial and Oral Surgery, University of Zurich, University Hospital Zurich, Plattenstrasse 11, CH-8032, Zurich, Switzerland.

Background: Bone necrosis of the jaw is a serious condition with a broad differential diagnosis of pathologies such as cutaneous histiocytosis, bone metastases or malignant tumours. In addition to the most common cause, medication related osteonecrosis of the jaw (MRONJ), one must consider a number of other causes, such as histiocytosis. Langerhans cell histiocytosis (LCH) is a histiocytic disorder with a large spectrum of clinical manifestations and with possible involvement of a variety of organs. Read More

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http://dx.doi.org/10.1186/s12903-018-0568-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994067PMC
June 2018
11 Reads

Preliminary report of histopathology associated with infection with tongue worms in Australian dogs and cattle.

Parasitol Int 2018 10 23;67(5):597-600. Epub 2018 May 23.

School of Animal and Veterinary Sciences, Charles Sturt University, Wagga Wagga, NSW 2678, Australia; Graham Centre for Agricultural Innovations, Wagga Wagga, NSW, Australia.

Tongue worms utilise herbivorous mammals as intermediate hosts and reside in the nasopharynx of carnivores as their definitive hosts. A recent study in south eastern Australia showed an unexpectedly high infection (67%) of wild dogs with these parasites. The present study aimed at determining the pathogenicity of the parasite in both definitive (dog) and intermediate (cattle) hosts by histopathology. Read More

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http://dx.doi.org/10.1016/j.parint.2018.05.011DOI Listing
October 2018
9 Reads

Calvarial intraosseous leiomyoma: Another consideration in children with suspected esosinophilic granuloma.

Neurol India 2018 May-Jun;66(3):866-868

Department of Neurosurgery, Zhongshan City People's Hospital, Zhongshan, Guangdong, China.

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http://dx.doi.org/10.4103/0028-3886.232331DOI Listing
September 2019
9 Reads

Histiocytic lesions of the orbit: A study of 9 cases.

Saudi J Ophthalmol 2018 Jan-Mar;32(1):40-44. Epub 2018 Mar 15.

Department of Ophthalmology, Ankara University Faculty of Medicine, Ankara, Turkey.

Purpose: To describe the clinical presentation, treatment, and outcome of patients with histiocytic lesions of the orbit.

Methods: Retrospective study of 9 patients treated and followed up between October 2001 and January 2018.

Results: Eight patients in our series were males and one patient was female. Read More

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http://dx.doi.org/10.1016/j.sjopt.2018.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943821PMC
March 2018
10 Reads

F-FDG PET/CT for the Evaluation of Primary Eosinophilic Granuloma of the Hypothalamus.

J Nucl Med Technol 2018 Sep 3;46(3):290-291. Epub 2018 May 3.

Department of Medical Imaging, University of Arizona, Tucson, Arizona; and.

A 21-y-old man who presented with polyuria and polydipsia was discovered to have diabetes insipidus due to eosinophilic granuloma of the hypothalamus. F-FDG PET/CT, which was performed as a metastatic work-up, revealed an intensely F-FDG-avid hypothalamic mass and no other sites of disease. Read More

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http://dx.doi.org/10.2967/jnmt.118.209957DOI Listing
September 2018
26 Reads

A case report of orbital Langerhans cell histiocytosis presenting as a orbital cellulitis.

Arch Soc Esp Oftalmol 2018 Oct 8;93(10):503-506. Epub 2018 Apr 8.

Unidad de Órbita y Oculoplástica, Servicio de Oftalmología, Hospital Universitario de Gerona Dr. Josep Trueta, Gerona, España.

Clinical Case: A 10-year-old girl was seen with a 3-week history of right upper lid swelling and with no other symptoms or fever. There was no recent history of sinusitis, trauma, or previous infection involving the periorbital area, or response to oral antibiotic treatment. Orbital computed tomography showed a lesion involving the upper margin of the orbit, and bone destruction at the orbital roof. Read More

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http://dx.doi.org/10.1016/j.oftal.2018.03.003DOI Listing
October 2018
14 Reads

[Langerhans cell histiocytosis with orbital involvement in an infant: Case report].

Arch Argent Pediatr 2018 04;116(2):e283-e287

Hospital Nacional Edgardo Rebagliati Martins, Departamento de Anatomía Patológica.

The Langerhans cell histiocytosis is a rare disease characterized by the clonal proliferation of CD1a + myeloid dendritic cells associated with a significant inflammatory component. The localized form of the disease is called eosinophilic granuloma. Bone involvement is common; in children, lytic lesions are most frequently found in the cranial dome being rare in the orbit. Read More

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http://dx.doi.org/10.5546/aap.2018.e283DOI Listing
April 2018
8 Reads

A "cure"ttable cause of secondary headache.

Neurol India 2018 Mar-Apr;66(2):577-578

Department of Radiology, Kerala Institute of Medical Sciences (KIMS), Trivandrum, Kerala, India.

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http://www.neurologyindia.com/text.asp?2018/66/2/577/227333
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http://dx.doi.org/10.4103/0028-3886.227333DOI Listing
September 2019
5 Reads
1.080 Impact Factor

Mepolizumab Treatment of Pediatric Eosinophilic Granulomatosis With Polyangiitis.

JAMA Dermatol 2018 04;154(4):486-487

Division of Dermatology, Augusta University, Augusta, Georgia.

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http://dx.doi.org/10.1001/jamadermatol.2017.5888DOI Listing
April 2018
8 Reads

Multidisciplinary approach in a case of Hand-Schüller-Christian disease with maxillary involvement.

Spec Care Dentist 2018 Mar 8;38(2):107-111. Epub 2018 Feb 8.

Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.

Langerhans cell histiocytosis (LCH) is a childhood pathology with a peak of incidence ranging from 1 to 4 years of age, though diagnosis is often made in adult age. LCH is clinically classified into three types: eosinophilic granuloma, Hand-Schuller-Christian disease and Abt-Letterer-Siwe disease. We report a case of Hand-Schüller-Christian disease with diabetes insipidus, skull and maxillary involvement in a 16-year-old boy referred to our observation for gradual increase in mobility of the teeth and subsequent gradual loss of the second premolars and the first molars of the upper jaw. Read More

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http://dx.doi.org/10.1111/scd.12273DOI Listing
March 2018
9 Reads

Abdominal Angiostrongyliasis: A Presentation of Eosinophilic Granulomatous Colitis.

Int J Surg Pathol 2018 Aug 26;26(5):475-478. Epub 2017 Dec 26.

1 University of Texas Southwestern Medical Center, Dallas, TX, USA.

We present a case of a 4-year-old girl with abdominal angiostrongyliasis who presented with persistent fevers, hepatosplenomegaly, acute abdominal pain, and eosinophilia. Computed tomography scan identified thickening of the ascending colon with a narrowed lumen. Endoscopic evaluation revealed ulcerations and erythema in the ascending colon. Read More

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http://dx.doi.org/10.1177/1066896917749929DOI Listing
August 2018
19 Reads

Mixed histiocytosis: A case report and published work review.

J Dermatol 2018 Apr 15;45(4):491-495. Epub 2017 Dec 15.

Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, China.

Histiocytoses are a group of heterogeneous diseases that encompass Langerhans cell histiocytosis and non-Langerhans cell histiocytosis. Cutaneous plane xanthoma is a non-Langerhans cell histiocytic disorder characterized by the presence of yellow-orange plaques on the face, neck, upper trunk and extremities. It can appear in association with several systemic diseases (including dyslipidemias, paraproteinemias, cardiovascular diseases and lymphoproliferative disorders), but is rarely connected with Langerhans cell histiocytoses. Read More

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http://dx.doi.org/10.1111/1346-8138.14179DOI Listing
April 2018
22 Reads

Eosinophilic granuloma of the mandible mimicking a periapical lesion.

J Dent Sci 2017 Dec 27;12(4):424-425. Epub 2017 Oct 27.

Department of Dentistry, Far Eastern Memorial Hospital, New Taipei City, Taiwan.

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http://dx.doi.org/10.1016/j.jds.2017.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395350PMC
December 2017
6 Reads

Eosinophiler Granulozyt – manchmal Freund, manchmal Feind.

Authors:
Alex Straumann

Ther Umsch 2017 Nov;74(6):289

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http://dx.doi.org/10.1024/0040-5930/a000916DOI Listing
November 2017
9 Reads

Intradural Eosinophilic Granuloma Invading Skull: Case Report and Review of the Literature.

Asian J Neurosurg 2017 Oct-Dec;12(4):698-700

Department of Pathology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.

Eosinophilic granuloma is a localized form of Langerhans cell histiocytosis, most commonly involving the skeletal system. Their origin from the dura is rare with only a handful of cases on record. We present one such rare case of an eosinophilic granuloma originating from the dura mater with secondary osseous invasion in an 11-year-old female child who presented with a swelling in the right parietal region. Read More

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http://dx.doi.org/10.4103/ajns.AJNS_47_15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652098PMC
November 2017
22 Reads

An unusual gastric tumour with gastric outlet obstruction.

Gut 2018 09 28;67(9):1645-1646. Epub 2017 Sep 28.

Department of Internal Medicine, E-Da Hospital/I-Shou University, Kaohsiung, Taiwan.

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http://dx.doi.org/10.1136/gutjnl-2017-315087DOI Listing
September 2018
13 Reads

Traumatic ulcerative granuloma with stromal eosinophilia: a malignant-appearing benign lesion.

Cutis 2017 Aug;100(2):E28-E31

Wilford Hall Ambulatory Surgical Center, San Antonio Uniformed Services Health Education Consortium, Texas, USA.

Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is an underreported diagnosis in dermatologic literature. Rapid expansion with an ulcerative clinical appearance often provokes fear of malignancy despite its benign nature. Traumatic ulcerative granuloma with stromal eosinophilia is thought to be a reactive tissue response to trauma, but CD30 mononuclear cells within a TUGSE lesion suggests the possibility of an underlying lymphoproliferative disorder. Read More

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August 2017
52 Reads