1,163 results match your criteria Eosinophilic Gastroenteritis


Eosinophilic Disorders of the Gastrointestinal Tract and Associated Abdominal Viscera: Imaging Findings and Diagnosis.

Radiographics 2022 Jun 24:220004. Epub 2022 Jun 24.

From the Department of Radiology (M.Y., A.D.T.A., Z.S.K., M.L.W., J.P.H., S.P.S., J.L.F., S.K.V.) and Department of Laboratory Medicine and Pathology (M.S.T.), Mayo Clinic, 200 2nd St SW, Rochester, MN 55905; and Department of Diagnostic Imaging, National University Health System, Singapore (L.L.S.T.).

Eosinophilic gastrointestinal disorders (EGIDs) are inflammatory conditions of the gastrointestinal tract that are characterized by tissue eosinophilia and end-organ dysfunction or damage. Primary EGIDs are associated with atopy and other allergic conditions, whereas secondary EGIDs are associated with underlying systemic diseases or hypereosinophilic syndrome. Within the spectrum of EGIDs, eosinophilic esophagitis is the most prevalent. Read More

View Article and Full-Text PDF

Follow-Up of a Rare Case of Eosinophilic Gastroenteritis Associated with Persistent Blood Eosinophilia and Multiple Food Allergies.

Diagnostics (Basel) 2022 Jun 2;12(6). Epub 2022 Jun 2.

Clinical Department 5, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.

Eosinophilic gastroenteritis (EGE) is a subgroup of the eosinophilic gastro-intestinal disorders (EGIDs), characterized by eosinophilic infiltration and chronic inflammation of the gastrointestinal tract. These are rare diseases with still incompletely elucidated causes and mechanisms, with frequently delayed diagnosis and variable outcome. Despite increased interest in eosinophilic diseases in recent years, fewer data have been published on EGE and no standardized diagnostic and therapeutic approach exists. Read More

View Article and Full-Text PDF

OX40 Expression in Eosinophils Aggravates OVA-Induced Eosinophilic Gastroenteritis.

Front Immunol 2022 2;13:841141. Epub 2022 Jun 2.

Department of Gastroenterology, Peking University Ninth School of Clinical Medicine, Beijing, China.

Background & Aims: Eosinophils are the main inflammatory effector cells that damage gastrointestinal tissue in eosinophilic gastrointestinal diseases (EGIDs). Activation of the OX40 pathway aggravates allergic diseases, such as asthma, but it is not clear whether OX40 is expressed in eosinophils to regulate inflammation in EGIDs. In this study, we assessed the expression and effect of OX40 on eosinophils in WT and eosinophilic gastroenteritis (EGE) mice. Read More

View Article and Full-Text PDF

Eosinophilic Ascites: An Infrequent Presentation of Eosinophilic Gastroenteritis.

Cureus 2022 Apr 20;14(4):e24303. Epub 2022 Apr 20.

Internal Medicine, Hospital Garcia de Orta, Almada, PRT.

Eosinophilic gastroenteritis (EGE) is an unusual and benign inflammatory disorder that mainly affects the digestive tract. Its main symptoms are cramp-like abdominal pain, nausea, vomiting, diarrhea, gastrointestinal bleeding, and weight loss. Laboratory results show peripheral eosinophilia. Read More

View Article and Full-Text PDF

Eosinophilic Gastritis With Linear Arrays of Pseudopolyps in the Antrum Treated With Exclusive Enteral Nutrition.

J Pediatr Gastroenterol Nutr 2022 05 30;74(5):e127. Epub 2021 Nov 30.

Department of Pediatrics, School of Medicine, Kyungpook National University, Daegu, Korea.

View Article and Full-Text PDF

Accurate and timely diagnosis of Eosinophilic Esophagitis improves over time in Europe. An analysis of the EoE CONNECT Registry.

United European Gastroenterol J 2022 Jun 16;10(5):507-517. Epub 2022 May 16.

Centro de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas, Madrid, Spain.

Background: Poor adherence to clinical practice guidelines for eosinophilic esophagitis (EoE) has been described and the diagnostic delay of the disease continues to be unacceptable in many settings.

Objective: To analyze the impact of improved knowledge provided by the successive international clinical practice guidelines on reducing diagnostic delay and improving the diagnostic process for European patients with EoE.

Methods: Cross-sectional analysis of the EoE CONNECT registry based on clinical practice. Read More

View Article and Full-Text PDF

Eosinophilic colitis: An entity on the rise.

Authors:
J M Remes-Troche

Rev Gastroenterol Mex (Engl Ed) 2022 Apr-Jun;87(2):133-134. Epub 2022 May 13.

Laboratorio de Fisiología Digestiva y Motilidad Gastrointestinal, Instituto de Investigaciones Médico Biológicas, Universidad Veracruzana, Veracruz, Veracruz, Mexico. Electronic address:

View Article and Full-Text PDF

[A case of eosinophilic gastroenteritis caused after the use of Seprafilm].

Nihon Shokakibyo Gakkai Zasshi 2022 ;119(5):459-465

Department of Gastroenterology, Osaka Rosai Hospital.

Eosinophilic gastroenteritis is a fairly uncommon condition. It has been suggested that allergic reactions may have played a role in the development of this illness. The case of a 66-year-old woman who had a total hysterectomy due to a right ovarian tumor is described here. Read More

View Article and Full-Text PDF

Whipple's disease with normal duodenal histology diagnosed by ileal biopsy using balloon endoscopy.

Clin J Gastroenterol 2022 May 6. Epub 2022 May 6.

Department of Gastroenterology, Nakagami Hospital, 610 Noborikawa, Okinawa, 904-2142, Japan.

A 34 year-old previously healthy Japanese woman presented with a 4 year history of migratory arthralgia, chronic diarrhea, mild fever, and 10 kg weight loss. She was initially misdiagnosed with seronegative arthritis, followed by eosinophilic gastroenteritis. Oral prednisolone was found to be ineffective. Read More

View Article and Full-Text PDF

Eosinophilic enteritis accompanied by cytomegalovirus disease: a case report.

BMC Gastroenterol 2022 Apr 28;22(1):209. Epub 2022 Apr 28.

Department of Gastroenterology, Mitsubishi Kyoto Hospital, Kyoto, Japan.

Background: Eosinophilic enteritis is a chronic inflammatory disorder of the intestinal tract that is characterized by eosinophil infiltration. Cytomegalovirus (CMV), a common virus, has a broad infectivity range. CMV is retained in the host body after infection. Read More

View Article and Full-Text PDF

Clinical profile and characteristics of eosinophilic esophagitis patients presenting with refractory gastroesophageal reflux disease in Makassar, Indonesia.

Pan Afr Med J 2022 2;41:93. Epub 2022 Feb 2.

Department of Internal Medicine, Faculty of Medicine, Universitas Hasanuddin, Makassar, South Sulawesi, Indonesia.

Refractory Gastroesophageal Reflux Disease (GERD) is a typical GERD that does not respond to Proton Pump Inhibitor (PPI) treatment for 8-12 weeks. One of the differential diagnoses for refractory GERD is eosinophilic esophagitis which is characterized by eosinophilic infiltration into the esophagus endothelium. However, to date, eosinophilic esophagitis is still poorly understood and data is still limited. Read More

View Article and Full-Text PDF

Nutritional and Psychological Considerations for Dietary Therapy in Eosinophilic Esophagitis.

Nutrients 2022 Apr 12;14(8). Epub 2022 Apr 12.

Department of Gastroenterology, Hospital Universitario de Caceres, 10004 Caceres, Spain.

The step-up empiric elimination diet, starting from one/two food groups of most local allergens remains the current gold standard for a dietary approach in eosinophilic esophagitis (EoE) patients. Milk, followed by wheat and egg, is the most frequent food that triggers EoE in pediatric and adult patients. Elimination diets, with restrictions over four food groups, may be limited to highly motivated patients, in which nutritional counseling is recommended. Read More

View Article and Full-Text PDF

Postpartum Eosinophilic Ascites: A Case Report.

Cureus 2022 Mar 18;14(3):e23301. Epub 2022 Mar 18.

Department of Internal Medicine, Hospital de Braga, Braga, PRT.

Eosinophilic gastrointestinal diseases (EGID) are a group of conditions characterized by histopathologic eosinophilic infiltrates in one or more segments of the gastrointestinal (GI) tract. It occurs in the absence of known causes for eosinophilia. It can affect every part of the gastrointestinal tract, but eosinophilic ascites (EA) is uncommon. Read More

View Article and Full-Text PDF

Eosinophilic Duodenal Ulcer Exacerbation after Helicobacter pylori Eradication in a 14-Year-Old Boy.

Tohoku J Exp Med 2022 Jun 21;257(2):153-156. Epub 2022 Apr 21.

Department of Pediatrics, Dokkyo Medical University.

Eosinophilic gastrointestinal disorders (EGIDs) cause various gastrointestinal symptoms due to infiltration of eosinophils into the gastrointestinal tract. Helicobacter pylori (H. pylori) is a microorganism that is associated with various diseases such as autoimmune diseases. Read More

View Article and Full-Text PDF

[Acute Diseases of the Esophagus - Esophagitis].

Ther Umsch 2022 04;79(3-4):209-211

Klinik für Gastroenterologie, gastrointestinale Onkologie und Endokrinologie, Universitätsmedizin Göttingen, Georg-August-Universität, Göttingen, Deutschland.

Acute Diseases of the Esopagus - Esophagitis Inflammation of the esophagus can be caused by various conditions including gastroesophageal reflux (GERD), immunosuppression, infections, allergens, or distinct medications. GERD will be covered in a separate article. Clinical symptoms include heartburn, retrosternal pain, dysphagia, or fetor ex ore. Read More

View Article and Full-Text PDF

Hypereosinophilic syndrome presenting as eosinophilic gastroenteritis disorder and splinter hemorrhages: A case report.

World J Gastrointest Pharmacol Ther 2022 Mar;13(2):23-29

Department of Pathology, All India Institute of Medical Sciences, Rishikesh 249203, India.

Background: Eosinophilia and related organ damage are extensively studied hot topics among rare disorders. Any addition to the cohort of available case reports of the same will be adding knowledge for better management of this less known entity.

Case Summary: In this article, we describe a 27-year-old Indo-Aryan man who presented with abdominal pain, abdominal distension, and loose stools for variable days. Read More

View Article and Full-Text PDF

Symptoms and complications that require urgent treatment and upper digestive comorbidities in eosinophilic esophagitis.

Dig Liver Dis 2022 06 11;54(6):842-844. Epub 2022 Apr 11.

Sección de Alergología del Hospital General Universitario de Ciudad Real, C / Obispo R Torija S/N, Ciudad Real CP 13005, Spain. Electronic address:

View Article and Full-Text PDF

Evidence-Based and Emerging Diet Recommendations for Small Bowel Disorders.

Am J Gastroenterol 2022 06 8;117(6):958-964. Epub 2022 Apr 8.

Academic Unit of Gastroenterology, Royal Hallamshire Hospital, Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, England.

Diet plays a key role in the manifestation and severity of gastrointestinal symptoms, with increasing research interest on the role of diet in small bowel disorders. There are predominantly 3 small bowel conditions that have potential dietary interventions. Self-reported nonceliac gluten/wheat sensitivity is prevalent. Read More

View Article and Full-Text PDF

[Eosinophilic gastrointestinal disease - a rare condition of unknown cause].

Authors:
Nikolaos Melas

Lakartidningen 2022 04 8;119. Epub 2022 Apr 8.

specialistläkare, sektionen för gastroenterologi och hepatologi, Centralsjukhuset Karlstad.

Eosinophilic gastrointestinal disease is a rare condition of unknown cause with rising incidence in adults and characterized by chronic inflammation in the gastrointestinal tract with accumulation of eosinophils in the gastrointestinal wall, without other apparent cause (e.g., infections, IBD). Read More

View Article and Full-Text PDF

The incidence of eosinophilic oesophagitis in 2007-2017 among children in North Denmark Region is lower than expected.

BMC Pediatr 2022 04 6;22(1):183. Epub 2022 Apr 6.

Department of Clinical Medicine, Aalborg University, Frederik Bajers Vej 7D, 9220, Aalborg, Denmark.

Background: In North Denmark Region (NDR), the incidence of Eosinophilic Oesophagitis (EoE) among adults has increased following a new biopsy protocol in 2011, whereas data on the incidence of EoE among children is lacking.

Aims: To describe the incidence of EoE in children aged 0-17 in NDR as well as diagnostic delay, clinical manifestations, treatment and complications.

Methods: This retrospective, register-based DanEoE cohort study included 18 children diagnosed with EoE between 2007-2017 in NDR. Read More

View Article and Full-Text PDF

[Human diseases caused by Anisakis simplex].

Rev Med Suisse 2022 Apr;18(776):634-638

Service d'immunologie et allergie, Centre hospitalier universitaire vaudois, 1011 Lausanne.

Anisakis simplex is a parasitic worm. It infects marine mammals that feed on fish and cephalopods, its intermediary hosts. Human disease is caused by accidental ingestion of Anisakis larvae. Read More

View Article and Full-Text PDF

[Diagnosis and Treatment of Eosinophilic Esophagitis].

Korean J Gastroenterol 2022 Mar;79(3):99-108

Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Korea.

Eosinophilic esophagitis (EoE) is a chronic, immune/antigen-mediated esophageal disease characterized by symptoms of esophageal dysfunction and eosinophil-predominant inflammation. The diagnostic criteria for EoE have changed with our growing knowledge over the past two decades. Esophageal eosinophilia, which responds histologically to a proton pump inhibitor (PPI) is not a distinct disease but a subset of EoE. Read More

View Article and Full-Text PDF

Prevalence of inflammatory versus neoplastic lesions in dogs with chronic gastrointestinal signs undergoing gastroduodenoscopy: 195 cases (2007-2015).

Res Vet Sci 2022 Sep 17;146:28-33. Epub 2022 Mar 17.

Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zurich, Switzerland. Electronic address:

Objectives: Prevalence of inflammatory enteropathy versus lymphoma in dogs undergoing gastroduodenoscopy has not been evaluated. This retrospective study assessed outcome from 195 client-owned dogs scheduled to undergo upper gastrointestinal endoscopy as the next diagnostic step.

Material And Methods: Cases were grouped into the following diagnoses according to WSAVA guidelines: lymphoplasmacytic enteritis (LPE), eosinophilic enteritis (EE), mixed-cell enteritis (ME), histologically normal biopsies (N), and lymphoma (L). Read More

View Article and Full-Text PDF
September 2022

Endoscopic diagnosis of chronic diarrhea.

DEN open 2022 Apr 28;2(1):e53. Epub 2021 Sep 28.

Department of Gastroenterology Steel Memorial Hirohata Hospital Hyogo Japan.

The prevalence of chronic diarrhea in the general population is reported to be 4%-5%. Since various pathological conditions cause diarrheal symptoms, etiological diagnosis of chronic diarrhea is difficult in many cases. Medical history taking, physical examinations, and laboratory testing are not adequately sensitive or specific, thus a colonoscopic investigation is frequently employed for etiological evaluation. Read More

View Article and Full-Text PDF

Eosinophilic Esophagitis With Subsequent Eosinophilic Colitis: Keeping a High Index of Suspicion.

Cureus 2022 Feb 9;14(2):e22073. Epub 2022 Feb 9.

Department of Gastroenterology and Hepatology, University of Connecticut Health, Farmington, USA.

The prevalence of eosinophilic esophagitis (EoE) has significantly increased, while, in comparison, eosinophilic gastroenteritis and colitis remain rare entities. The diagnosis and management of eosinophilic gastrointestinal (GI) disorders can be challenging given the non-specific manifestations and variable treatment response. Symptoms refractory to initial therapies (e. Read More

View Article and Full-Text PDF
February 2022

Should children with immunoglobulin E-mediated food allergy be screened for eosinophilic esophagitis?

Ann Allergy Asthma Immunol 2022 Jun 12;128(6):724-725. Epub 2022 Mar 12.

University of Rochester School of Medicine and Dentistry, Rochester, New York; Allergy and Clinical Immunology, Rochester Regional Health, Rochester, New York.

View Article and Full-Text PDF

Benralizumab Completely Depletes Gastrointestinal Tissue Eosinophils and Improves Symptoms in Eosinophilic Gastrointestinal Disease.

J Allergy Clin Immunol Pract 2022 Jun 10;10(6):1598-1605.e2. Epub 2022 Mar 10.

Human Eosinophil Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.

Background: Previous studies of targeted eosinophil biologics in eosinophilic esophagitis have yielded mixed results. Possible explanations include incomplete eosinophil depletion with anticytokine (anti-IL-5) treatments and/or irreversible fibrotic tissue changes contributing to symptomatology.

Objective: To characterize the therapeutic effect of eosinophil depletion in patients with hypereosinophilic syndrome with varied eosinophilic gastrointestinal (GI) disorders. Read More

View Article and Full-Text PDF

Colonic mucosal eosinophilia and immunohistochemical expression of COX-2 and NF-kB in patients with irritable bowel syndrome.

Eur J Gastroenterol Hepatol 2022 05;34(5):512-517

Department of Endemic Medicine.

Background: There is growing evidence that eosinophilic infiltration can release mediators which are harmful to the intestinal epithelium in patients with irritable bowel syndrome (IBS). Although cyclooxygenase 2 (COX-2) and nuclear factor-kappa beta (NF-kB) expression had been previously reported to increase in many inflammatory conditions, there is a paucity in data investigating their expressions in IBS. Our aim was to evaluate colonic mucosal eosinophilia and immunohistochemical expression of COX-2 and NF-kB in patients with irritable bowel syndrome. Read More

View Article and Full-Text PDF

Beige mucosa observable under narrow-band imaging indicates the active sites of eosinophilic esophagitis.

J Gastroenterol Hepatol 2022 May 9;37(5):891-897. Epub 2022 Mar 9.

Division of Gastroenterology, Department of Internal Medicine 2, Kawasaki Medical School, Okayama, Japan.

Background And Aim: The majority of patients with eosinophilic esophagitis (EoE) are likely to have observable features under narrow-band imaging, namely beige mucosa. However, the histological features and clinical implications of beige mucosa have not been investigated. The aim of this study was to determine whether beige mucosa could serve as an endoscopic marker for predicting active inflammatory sites of EoE. Read More

View Article and Full-Text PDF