394 results match your criteria Eosinophilic Folliculitis

Eosinophilic pustular folliculitis of infancy: A rare diagnosis in children.

Clin Case Rep 2021 May 11;9(5):e04167. Epub 2021 May 11.

Department of Dermatology Aarhus University Hospital Aarhus Denmark.

Remember EPFI as a differential diagnosis in children with a rash on the scalp and no effect of antibiotic treatment. Read More

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Predictive Model for Differential Diagnosis of Inflammatory Papular Dermatoses of the Face.

Ann Dermatol 2020 Aug 30;32(4):298-305. Epub 2020 Jun 30.

Department of Dermatology, Seoul National University Bundang Hospital, Seongnam, Korea.

Background: The clinical features of inflammatory papular dermatoses of the face are very similar. Their clinical manifestations have been described on the basis of a small number of case reports and are not specific.

Objective: This study aimed to use computer-aided image analysis (CAIA) to compare the clinical features and parameters of inflammatory papular dermatoses of the face and to develop a formalized diagnostic algorithm based on the significant findings. Read More

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Infantile Eosinophilic Pustular Folliculitis: A Case Report.

J Cosmet Dermatol 2021 Apr 20. Epub 2021 Apr 20.

Department of Pathology, Selcuk University Faculty of Medicine, Konya, Turkey.

Background: Infantile eosinophilic pustular folliculitis (I-EPF) is a rare disease characterized by pruritic vesicles and sterile pustules on the erythematous surface of the scalp and facial localization, usually seen in the neonatal period. It is essential to show the presence of dense eosinophils in the diagnosis of pustules. Histopathological examination of the hair follicles by eosinophils infiltration is determined. Read More

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Uncommon localisation of Ofuji disease in a Moroccan patient.

BMJ Case Rep 2021 Apr 13;14(4). Epub 2021 Apr 13.

Dermatology-Venerology Department, Mohammed V University of Rabat, Rabat, Morocco.

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Eosinophilic folliculitis, eosinophilic dermatosis of hematologic malignancy and acneiform follicular mucinosis: Two case reports and a review of the literature highlighting the spectrum of histopathology.

J Cutan Pathol 2021 Mar 18;48(3):439-450. Epub 2020 Dec 18.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.

Within the literature, there is overlap in the histopathological features described in eosinophilic folliculitis associated with chronic lymphocytic leukemia (CLL), eosinophilic dermatosis of hematologic malignancy, and acneiform follicular mucinosis. These disorders are described with varying degrees of superficial and deep lymphocytic and eosinophilic inflammation demonstrating perivascular, perifollicular, and folliculocentric involvement with or without follicular mucin deposition. Given significant histopathological overlap, these diagnoses may represent a continuum on a spectrum of dermatoses. Read More

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Treatment of eosinophilic pustular folliculitis with benralizumab in a 13-year-old girl.

J Eur Acad Dermatol Venereol 2021 Jun 10;35(6):e401-e403. Epub 2021 Mar 10.

Pediatric Skin Center, Dermatology Department, University Children's Hospital Zurich, Zurich, Switzerland.

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A Case of Eosinophilic Pustular Folliculitis since Birth.

Children (Basel) 2021 Jan 7;8(1). Epub 2021 Jan 7.

Department of Dermatology, Ehime University Graduate School of Medicine, Ehime 791-0295, Japan.

A newborn male infant presented with multiple pustules and erosions with erythema involving his scalp and forehead at birth. One week after birth, new pustules continued to appear, forming crusted, ring-shaped plaques with pigmentation. Tests for possible pathogens were negative. Read More

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January 2021

Eosinophilic pustular folliculitis (EPF) in a patient with HIV infection.

Infection 2020 Nov 25. Epub 2020 Nov 25.

Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45122, Essen, Germany.

Eosinophilic pustular folliculitis is a chronic, recurrent dermatosis, of unknown etiology, which is histologically characterized by folliculotropic inflammatory infiltrates with admixed eosinophils in the dermis. It has often presented with immunosuppression and especially with HIV-Infection. In the HAART-era, eosinophilic pustular folliculitis has become a rarity. Read More

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November 2020

A Case of Eosinophilic Pustular Folliculitis Associated With Herpes Zoster.

Am J Dermatopathol 2021 Apr;43(4):298-299

Department of Dermatology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Republic of Korea.

Abstract: Patients with eosinophilic pustular folliculitis (EPF), a sterile eosinophilic infiltration of hair follicles, often present with papulopustules that tend to form annular plaques. Histopathologic examination revealed eosinophilic infiltration around the pilosebaceous units and eosinophilic microabscess formation. Although the pathogenesis of EPF is unknown, T-helper type 2 immune responses were suggested to be important based on their stimulating effect on the sebaceous glands. Read More

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Papuloerythroderma of Ofuji.

JAMA Dermatol 2020 12;156(12):1365

Department of Dermatology, National Clinical Research Center for Dermatologic and Immunologic Diseases, Translational Medicine Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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December 2020

Eosinophilic folliculitis due to wearing protective gear in citizens volunteering for sanitation services during the COVID-19 pandemic - an original epidemiological, clinical, dermoscopic, and laboratory-based study.

Antonio Chuh

Int J Dermatol 2020 Dec 11;59(12):1468-1474. Epub 2020 Oct 11.

Department of Family Medicine and Primary Care, The University of Hong Kong and Queen Mary Hospital, Pokfulam, Hong Kong.

Background: An association between wearing protective gear and eosinophilic folliculitis has not been reported. We aimed to investigate such during the COVID-19 pandemic.

Methods: In three outpatient clinics, we hand-reviewed records of all patients having consulted us during a Study Period (90 days) in the early phase of the pandemic. Read More

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December 2020

A Case of Ofuji Disease Successfully Treated with the Combination of Low-Dose Indomethacin and Topical Tacrolimus.

Case Rep Dermatol 2020 May-Aug;12(2):155-158. Epub 2020 Aug 18.

Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.

Eosinophilic pustular folliculitis (EPF) (Ofuji disease) is a chronic, noninfectious pruritic cutaneous disorder of unknown etiology. No official guidelines are available for its treatment. Herein we present the case of a 59-year-old Caucasian man admitted to our outpatient clinic due to a generalized itchy skin rash characterized by papulo-pustules involving the face, trunk, and limbs. Read More

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Human Polyomavirus 6 Detected in Cases of Eosinophilic Pustular Folliculitis.

J Infect Dis 2021 May;223(10):1724-1732

Department of Microbiology and Infection, Kochi Medical School, Kochi University, Kochi, Japan.

Background: Human polyomaviruses (HPyVs) have been associated with several cutaneous inflammatory conditions. More investigation is needed to identify further presentations of cutaneous pathology associated with HPyVs. Our aim was to investigate the possible association of skin-tropic HPyVs with folliculitis, particularly eosinophilic pustular folliculitis (EPF). Read More

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Eosinophilic Dermatoses: Recognition and Management.

Am J Clin Dermatol 2020 Aug;21(4):525-539

Dermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Eosinophilic dermatoses encompass a broad spectrum of diseases of different etiologies hallmarked by eosinophilic infiltration of the skin and/or mucous membranes, with or without associated blood eosinophilia. The wide range of dermatological manifestations of this spectrum, including nodules and plaques, pustules, blisters, ulcers, and urticarial lesions, is reflected in a non-univocal classification system. We identified six groups of eosinophilic dermatoses based on the predominant anatomic level of involvement: (1) epidermal; (2) of the dermal-epidermal junction; (3) dermal; (4) of the hypodermis and muscle fascia; (5) of the pilosebaceous unit; and (6) vascular/perivascular. Read More

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Eosinophilic folliculitis of the scalp associated with PD-1/PDL1 inhibitors.

J Cosmet Dermatol 2020 Dec 12;19(12):3367-3370. Epub 2020 Apr 12.

Department of Ematology, Oncology and Dermatology, "Sapienza" University of Rome, Rome, Italy.

Background: Immune checkpoint inhibitors are monoclonal antibodies which target immune "checkpoints" enhancing T cell-mediated cytotoxic and antitumor responses. Together to the amazing results, these drugs are associated with some peculiar adverse events called immune-related adverse events. Alopecia is one of these. Read More

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December 2020

Eosinophilic pustular folliculitis on the vulva of a patient with cervical cancer.

J Dermatol 2020 Jun 15;47(6):e221-e222. Epub 2020 Mar 15.

Department of Dermatology, Shinshu University School of Medicine, Matsumoto, Japan.

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Thalidomide in the Treatment of Sweet's Syndrome and Eosinophilic Folliculitis Associated With Immune Reconstitution Inflammatory Syndrome.

Front Med (Lausanne) 2019 21;6:343. Epub 2020 Jan 21.

Department of Dermatology and Venereology, First Affiliated Hospital of Kunming Medical University, Kunming, China.

Sweet's syndrome and eosinophilic folliculitis are aseptic inflammatory dermatitis mainly because of infiltrated neutrophils and eosinophils on skin, respectively. These diseases rarely overlap or coexist in the same patient, especially co-occur in HIV infected patient. Here, we report a rare case of an AIDS patient who developed eosinophilic folliculitis and Sweet's syndrome within 1 month of initial antiretroviral therapy, presumably due to immune reconstitution inflammatory syndrome. Read More

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January 2020

Malassezia (Pityrosporum) Folliculitis Incognito: Malessezia-associated Folliculitis Masked by Topical Corticosteroid Therapy.

Cureus 2020 Jan 1;12(1):e6531. Epub 2020 Jan 1.

Dermatology/Dermatopathology, Compass Dermatopathology, Inc., San Diego, USA.

Malassezia (Pityrosporum) folliculitis usually appears as pruritic monomorphous papules and pustules on the upper back, chest, extensor arms and face. Acne vulgaris, bacterial folliculitis, eosinophilic folliculitis and systemic corticosteroid-induced acne can clinically mimic the fungal-caused acneiform condition. The designation incognito is used to describe tinea or scabies when the characteristic presentation is masqueraded by the application of topical corticosteroid treatment. Read More

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January 2020


Harefuah 2020 Jan;159(1):34-37

Department of Dermatology, Emek Medical Center, Afula, Israel.

Aims: This study aims to critically review the pros and cons of biological drugs as treatments and triggers of eosinophilic dermatoses.

Background: Eosinophilic dermatoses syndromes are rare diseases with a prominent eosinophilic infiltration mechanism. These syndromes have several known treatments with limited success. Read More

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January 2020

Eosinophilic dermatoses.

J Dtsch Dermatol Ges 2019 10 27;17(10):1039-1051. Epub 2019 Sep 27.

Department of Dermatology, University Hospital, Jena, Germany.

Eosinophilic dermatoses are a heterogeneous group of diseases, characterized by an eosinophil-rich infiltrate and/or degranulation of eosinophils. Blood eosinophilia may be an associated feature. Typical, albeit not specific histological findings include 'flame figures', which are caused by the accumulation of cationic proteins released by eosinophils and subsequent collagen denaturation. Read More

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October 2019

Suspected eosinophilic pustular folliculitis presenting as rapidly evolving acneiform eruption.

J Eur Acad Dermatol Venereol 2020 Jan 9;34(1):e43-e44. Epub 2019 Sep 9.

San Gallicano Dermatological Institute, IRCCS, Rome, Italy.

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January 2020

Upregulation of IL-36 cytokines in folliculitis and eosinophilic pustular folliculitis.

Australas J Dermatol 2020 Feb 19;61(1):e39-e45. Epub 2019 Aug 19.

Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Background: Members of the interleukin (IL)-36 family, IL-36α, IL-36β and IL-36γ, are potent chemoattractive cytokines for neutrophils and eosinophils. IL-36 receptor antagonist (IL-36Ra) inhibits IL-36α, IL-36β and IL-36γ activity. However, the immunohistological expression of IL-36α, IL-36β, IL-36γ and IL-36Ra has never been addressed in normal follicles, folliculitis or eosinophilic pustular folliculitis (EPF). Read More

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February 2020

Eosinophilic folliculitis in a patient with chronic myelomonocytic leukemia.

JAAD Case Rep 2019 Aug 31;5(8):656-659. Epub 2019 Jul 31.

Department of Dermatology, University of Florida College of Medicine, Gainesville, Florida.

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Methotrexate for papuloerythroderma of Ofuji.

Clin Exp Dermatol 2020 Mar 21;45(2):241-243. Epub 2019 May 21.

Department of Dermatology, Kingston Hospital NHS Foundation Trust, London, UK.

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High accuracy of recognition of common forms of folliculitis by dermoscopy: An observational study.

J Am Acad Dermatol 2019 Aug 23;81(2):463-471. Epub 2019 Mar 23.

Division of Mycology, Department of Microbiology, Faculty of Medicine, University of Çukurova, Adana, Turkey.

Background: Clinical differentiation of folliculitis types is challenging. Dermoscopy supports the recognition of folliculitis etiology, but its diagnostic accuracy is not known.

Objective: To assess the diagnostic accuracy of dermoscopy for folliculitis. Read More

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An aggressive case of granulomatous eosinophilic pustular folliculitis on the face.

JAAD Case Rep 2019 Mar 22;5(3):237-239. Epub 2019 Feb 22.

Department of Dermatology, Nippon Medical School, Tokyo, Japan.

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Eosinophilic pustular folliculitis of infancy suppressed with cetirizine.

Pediatr Dermatol 2019 May 21;36(3):395-396. Epub 2019 Feb 21.

Department of Dermatology, Kocaeli University School of Medicine, Kocaeli, Turkey.

Eosinophilic pustular folliculitis of infancy is a rare inflammatory disease characterized by recurrent, itchy sterile pustules mainly located on the scalp. Topical agents are mostly effective to suppress the symptoms in the majority of cases. However, systemic agents that are safe for long-term use are required for patients with widespread or resistant lesions. Read More

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