2,184,066 results match your criteria Environmental toxicology and chemistry / SETAC[Journal]


[Recent studies on the signaling pathways implicated myopia].

Zhonghua Yan Ke Za Zhi 2019 Feb;55(2):148-152

Eye Institute of Xiamen University, Fujian Provincial Key Laboratory of Ophthalmology and Visual Science, Xiamen 361102, China.

Myopia has emerged as one of the major health issues in China given its increasingly high prevalence. It is generally accepted that myopia is the result of a complex interaction of environmental exposures and genetic predisposition. Many studies have indicated that abnormal visual stimulation regulates retinal neurotransmitters and growth factors to release resulting in scleral remodeling and axial elongation through signaling pathway transduction. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2019.02.016DOI Listing
February 2019

Local oestrogen therapy modulates extracellular matrix and immune response in the vaginal tissue of post-menopausal women with severe pelvic organ prolapse.

J Cell Mol Med 2019 Feb 17. Epub 2019 Feb 17.

Department of Physiology, University of Toronto, Toronto, ON, Canada.

This study investigates the effect of local oestrogen therapy (LET) on the expression of proteins participating in collagen/elastin biogenesis and immune markers in vaginal tissues of post-menopausal women with severe pelvic organ prolapse (POP). Vaginal biopsies were collected from the anterior vaginal wall of informed and consented 52 post-menopausal women with severe POP undergoing total hysterectomy. Twenty-nine of the 52 women were treated with LET (in the form of vaginal oestrogen cream or tablet), while the remaining 23 untreated patients served as the controls. Read More

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http://dx.doi.org/10.1111/jcmm.14199DOI Listing
February 2019

Nutrition and its role in human evolution.

J Intern Med 2019 Feb 17. Epub 2019 Feb 17.

Vice Chancellor and Dean for Agriculture and Life Sciences, Texas A&M AgriLife, College Station, TX, USA.

Our understanding of human evolution has improved rapidly over recent decades, facilitated by large-scale cataloguing of genomic variability amongst both modern and archaic humans. It seems clear that the evolution of the ancestors of chimpanzees and hominins separated 7-9 million years ago with some migration out of Africa by the earlier hominins; Homo sapiens slowly emerged as climate change resulted in drier, less forested African conditions. The African populations expanded and evolved in many different conditions with slow mutation and selection rates in the human genome, but with much more rapid mutation occurring in mitochondrial DNA. Read More

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http://dx.doi.org/10.1111/joim.12878DOI Listing
February 2019

Characterizing Perceptions Around the Patient-Oncologist Relationship: a Qualitative Focus Group Analysis.

J Cancer Educ 2019 Feb 16. Epub 2019 Feb 16.

Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA.

The purpose of the current study was to characterize the experiences of cancer patients and their caregiver/family members around their relationship with their oncologist, health care team, and the hospital environment. Participants were recruited from The Ohio State University Comprehensive Cancer Center. Participant sociodemographic factors were assessed. Read More

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http://dx.doi.org/10.1007/s13187-019-1481-6DOI Listing
February 2019

Evaluating the health risk of metals (Zn, Cr, Cd, Ni, Pb) in staple foods from Lagos and Ogun States, Southwestern Nigeria.

Environ Monit Assess 2019 Feb 16;191(3):167. Epub 2019 Feb 16.

Department of Pure and Applied Zoology, Federal University of Agriculture, Abeokuta, Ogun State, PMB 2240, Nigeria.

The study evaluated the health risk of metals in commonly consumed staple foods from Lagos and Ogun states, southwestern Nigeria. One hundred and thirty-three food samples were collected and analyzed for Zn, Cr, Cd, Ni, and Pb using atomic absorption spectrophotometric method. Data collected were analyzed for simple descriptive and inferential statistics using SPSS for Windows. Read More

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http://dx.doi.org/10.1007/s10661-019-7307-5DOI Listing
February 2019

Zarqa River pollution: impact on its quality.

Environ Monit Assess 2019 Feb 16;191(3):166. Epub 2019 Feb 16.

Royal Scientific Society, Amman, Jordan.

Pollutants released to the Zarqa River have been identified, quantified, and linked to their sources. The methodology included field observation of the river, collection of available quality data, literature review, and grab sampling. Identified pollution sources to the Zarqa River are wastewater treatment plants, overflow of wastewater pumping stations, and leaks from sewer lines and manholes that pass through the riverbed, in addition to industrial, commercial, domestic, and agricultural activities along the river course. Read More

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http://dx.doi.org/10.1007/s10661-019-7283-9DOI Listing
February 2019

The Clinical and Molecular Epidemiology of CTX-M-9 Group Producing Enterobacteriaceae Infections in Children.

Infect Dis Ther 2019 Feb 16. Epub 2019 Feb 16.

Research Service, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, USA.

Introduction: The pandemic of extended-spectrum beta-lactamase-(ESBL)-producing Enterobacteriaceae (Ent) is strongly linked to the dissemination of CTX-M-type-ESBL-Ent. We sought to define the epidemiology of infections in children due to an emerging resistance type, CTX-M-9-group-producing-Ent (CTX-M-9-grp-Ent).

Methods: A retrospective matched case-control analysis of children with CTX-M-9-grp-Ent infections who received medical care at three Chicago area hospitals was performed. Read More

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http://dx.doi.org/10.1007/s40121-019-0237-2DOI Listing
February 2019

Breakthroughs and new horizons in reproductive biology of rare and endangered animal species.

Biol Reprod 2019 Feb 17. Epub 2019 Feb 17.

Academic Unit of Reproductive and Developmental Medicine, University of Sheffield, Sheffield S10 2SF, UK.

Because of higher extinction rates due to human and natural factors, more basic and applied research in reproductive biology is required to preserve wild species and design proper strategies leading to sustainable populations. The objective of the review is to highlight recent, inspiring breakthroughs in wildlife reproduction science that will set directions for future research and lead to more successes in conservation biology. Despite new tools and approaches allowing a better and faster understanding of key mechanisms, we still know little about reproduction in endangered species. Read More

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http://dx.doi.org/10.1093/biolre/ioz031DOI Listing
February 2019

Maternal blood pressure, cord glucocorticoids, and child neurodevelopment at 2 years of age: a birth cohort study.

Am J Hypertens 2019 Feb 16. Epub 2019 Feb 16.

Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Background: Pregnancy hypertensive disorders have impaired neurodevelopment in offspring. We aimed to explore the association of normal range maternal blood pressure (BP) with child neurodevelopment, as well as the possible role of placental 11-beta-hydroxysteroid dehydrogenase type 2 (11β-HSD2) therein.

Methods: Among 1,008 mother-child pairs recruited in Wuhan, China, in 2013-2015, we measured maternal third-trimester BP (systolic and diastolic BP, SBP and DBP) and cord glucocorticoids (cortisol and cortisone), a marker reflecting placental 11β-HSD2 activity. Read More

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http://dx.doi.org/10.1093/ajh/hpz024DOI Listing
February 2019

Scaffolding clinical reasoning of medical students with virtual patients: effects on diagnostic accuracy, efficiency, and errors.

Diagnosis (Berl) 2019 Feb 18. Epub 2019 Feb 18.

Medizinische Klinik und Polklinik IV, University Hospital, LMU Munich, Munich, Germany.

Background Understanding clinical reasoning is a major challenge in medical education research. Little is known about the influence of scaffolding and feedback on the clinical reasoning of medical students. The aim of this study was to measure the effects of problem representation (cognitive representation of a clinical case) and structured scaffolding for reflection with or without feedback on the diagnostic efficiency and characterization of diagnostic errors of medical students. Read More

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http://dx.doi.org/10.1515/dx-2018-0090DOI Listing
February 2019

PROFIT, a PROspective, randomised placebo controlled feasibility trial of Faecal mIcrobiota Transplantation in cirrhosis: study protocol for a single-blinded trial.

BMJ Open 2019 Feb 15;9(2):e023518. Epub 2019 Feb 15.

James Black Centre, School of Immunology & Microbial Sciences, Faculty of Life Sciences & Medicine, King's College London, London, UK.

Introduction: Patients with advanced cirrhosis have enteric bacterial dysbiosis and translocation of bacteria and their products across the gut epithelial barrier. This culminates in systemic inflammation and endotoxaemia, inducing innate immune dysfunction which predisposes to infection, and development of complications such as bleeding, sepsis and hepatic encephalopathy. This feasibility study aims to assess the safety of administering faecal microbiota transplantion to patients with cirrhosis and explore the effect of the intervention on their prognosis by achieving restoration of a healthy gut microbiome. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-023518DOI Listing
February 2019

Lifetime exposure to rubber dusts, fumes and N-nitrosamines and cancer mortality in a cohort of British rubber workers with 49 years follow-up.

Occup Environ Med 2019 Feb 16. Epub 2019 Feb 16.

Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

Objectives: To quantitatively evaluate exposure-response associations between occupational exposures to rubber dust, fumes and N-nitrosamines and cancer mortality in the UK rubber industry.

Methods: Competing risk survival analyses were used to examine cancer mortality risk in a cohort of 36 441 males aged 35+ years employed in the British rubber industry in 1967, followed up to 2015 (94% mortality). Exposure measurements are based on a population-specific quantitative job-exposure matrix for rubber dust, rubber fumes and N-nitrosamines from the EU-EXASRUB project. Read More

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http://dx.doi.org/10.1136/oemed-2018-105181DOI Listing
February 2019

Job-exposure matrix for historical exposures to rubber dust, rubber fumes and n-Nitrosamines in the British rubber industry.

Occup Environ Med 2019 Feb 16. Epub 2019 Feb 16.

Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

Objectives: To develop a quantitative historical job-exposure matrix (JEM) for rubber dust, rubber fumes and n-Nitrosamines in the British rubber industry for 1915-2002 to estimate lifetime cumulative exposure (LCE) for a cohort of workers with 49 years follow-up.

Methods: Data from the EU-EXASRUB database-rubber dust (n=4157), rubber fumes (n=3803) and n-Nitrosamines (n=10 115) collected between 1977 and 2002-were modelled using linear mixed-effects models. Sample year, stationary/personal measurement, industry sector and measurement source were included as fixed explanatory variables and factory as random intercept. Read More

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http://dx.doi.org/10.1136/oemed-2018-105182DOI Listing
February 2019

Extraction and characterization of high purity chitosan by rapid and simple techniques from mud crabs taken from Abbottabad.

Pak J Pharm Sci 2019 Jan;32(1):171-175

Department of Zoology, Government Post Graduate College No.1, Abbottabad, Pakistan.

Chitosan and chitosan based materials offer diverse applications in the field of biotechnology, nanotechnology, pharmaceuticals, environmental protection and tissue engineering due to their various biological and physicochemical properties. Major sources of chitosan are shrimps, crabs and lobsters. Properties of chitosan differ with the degree of deacetylation and the molecular weight. Read More

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January 2019

The analysis of the possibility of using biological tests for assessment of toxicity of leachate from an active municipal landfill.

Environ Toxicol Pharmacol 2019 Feb 11;67:94-101. Epub 2019 Feb 11.

Engineering Institute, State University of Applied Sciences in Nowy Sącz, Zamenhofa 1a St., 33-300, Nowy Sącz, Poland. Electronic address:

One of the consequence of municipal waste deposition is the production of landfill leachate. Its volume and composition is determined by numerous factors, including waste composition, landfill age and the volume of precipitation. Leachate may contain a number of mineral and organic compounds, the volume of which must be controlled regularly. Read More

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http://dx.doi.org/10.1016/j.etap.2019.01.013DOI Listing
February 2019

Association between high levels of inflammatory markers and cognitive outcomes at 4 years of age: The Rhea mother-child cohort study, Crete, Greece.

Cytokine 2019 Feb 14;117:1-7. Epub 2019 Feb 14.

Department of Social Medicine, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, USA.

There is growing evidence associating inflammatory markers in complex, higher order neurological functions, such as cognition and memory. We examined whether high levels of various inflammatory markers are associated with cognitive outcomes at 4 years of age in a mother-child cohort in Crete, Greece (Rhea study). We included 642 children in this cross-sectional study. Read More

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http://dx.doi.org/10.1016/j.cyto.2019.01.010DOI Listing
February 2019

Assessing the threats of organophosphate esters (flame retardants and plasticizers) to drinking water safety based on USEPA oral reference dose (RfD) and oral cancer slope factor (SFO).

Water Res 2019 Feb 1;154:84-93. Epub 2019 Feb 1.

School of Environmental Science and Engineering, Tianjin University, Tianjin, 300072, China; School of Marine Science and Technology, Tianjin University, Tianjin, 300072, China. Electronic address:

As one group of emerging pollutants, the threat of organophosphate esters (flame retardants and plasticizers, OPEs) to drinking water safety is not well recognized. Now, the oral reference dose (RfD) and oral cancer slope factor (SFO) of OPEs have been updated by USPEA, therefore the threat of OPEs to drinking water safety could be assessed. In this study, occurrence, health risk and key impact factor of OPEs in drinking water of China were analyzed covering 79 cities, whose population and gross domestic product (GDP) accounted for 28. Read More

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http://dx.doi.org/10.1016/j.watres.2019.01.035DOI Listing
February 2019

Civil conflict, domestic violence, and poverty as predictors of corporal punishment in Colombia.

Child Abuse Negl 2019 Feb 14;90:108-119. Epub 2019 Feb 14.

Department of Psychology and School of Social Work, University of Michigan, Ann Arbor, MI 48109, United States.

Background: With lingering effects from more than 50 years of war, young children in Colombia are exposed to multiple risk factors such as poverty, civil conflict, and domestic violence. In addition to these environmental stressors, public and legal support for corporal punishment remains high, which is shown by the high prevalence of young children exposed to corporal punishment in Colombia.

Objective: The purpose of this study is to identify individual, family, and municipality-level predictors of corporal punishment (i. Read More

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http://dx.doi.org/10.1016/j.chiabu.2019.02.003DOI Listing
February 2019

Importance of sperm density in assessing the toxicity of metals to the fertilization of broadcast spawners.

Ecotoxicol Environ Saf 2019 Feb 14;172:547-555. Epub 2019 Feb 14.

Faculty of Engineering Sciences, University College London, GPO Box 2471, Adelaide SA 5001, Australia.

Many marine invertebrates reproduce through broadcast spawning, where sperm and eggs are released into the water column and are vulnerable to toxicants present in the environment. The potential impacts of toxicants on spawning success are often assessed through laboratory-based fertilization tests. In most cases, these tests assess toxicant impacts at a single, pre-defined sperm density, based on a sperm:egg ratio that ensures high fertilization success (≥70-80%) in a filtered seawater control. Read More

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http://dx.doi.org/10.1016/j.ecoenv.2019.01.053DOI Listing
February 2019

Real-world effectiveness of antipsychotic monotherapy and polytherapy in 1543 patients with acute-phase schizophrenia.

Asian J Psychiatr 2019 Feb 8;40:82-87. Epub 2019 Feb 8.

Department of Psychiatry, Numazu Chuo Hospital, Numazu, Japan.

Purpose: The effectiveness of antipsychotic treatments in the acute phase of schizophrenia in actual clinical practice remains somewhat unclear. Therefore, the purpose of the present naturalistic, multi-center study conducted from 1 year starting in September 2017 was to examine the response rate to an initial or second antipsychotic in newly admitted patients with acute-phase schizophrenia, as well as the response rate and quality of augmentation with two antipsychotics in patients who failed to respond to both the initial and second antipsychotics.

Results: In total, there were 660 (42. Read More

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http://dx.doi.org/10.1016/j.ajp.2019.02.005DOI Listing
February 2019

Treatments for color removal from wastewater: State of the art.

J Environ Manage 2019 Feb 14;236:727-745. Epub 2019 Feb 14.

Department of Civil Engineering and Architecture, University of Pavia, via Ferrata 1, 27100, Pavia, Italy. Electronic address:

It is evident from many recent papers that release of colored wastewater into the environment is source of pollution and this is a problem that particularly affect textile, dyeing and food industries. The review: (i) presents an analysis of various mechanisms involved in the different processes for color removal; (ii) describes conveniences and disadvantages that may exist in adopting one type of treatment in spite of another; (iii) reports the results of approximately 180 experimental tests. Both examples of treatments already widely applied to the real scale and still in the experimental phase are reported. Read More

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http://dx.doi.org/10.1016/j.jenvman.2018.11.094DOI Listing
February 2019

Co-pretreatment of wheat straw by potassium hydroxide and calcium hydroxide: Methane production, economics, and energy potential analysis.

J Environ Manage 2019 Feb 14;236:720-726. Epub 2019 Feb 14.

College of Chemical Engineering, Beijing University of Chemical Technology, Beijing, 100029, China. Electronic address:

To improve the methane production of wheat straw (WS), the mono-pretreatment (MP) and co-pretreatment (CP) of WS with KOH and Ca(OH) were conducted in this study. The results showed that the MP with KOH presented better effects than the MP with Ca(OH). However, the CP with 2% KOH combined with 1% Ca(OH) displayed similar effects to those of the MP with 3% KOH, obtaining the cumulative methane yield of 239. Read More

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http://dx.doi.org/10.1016/j.jenvman.2019.01.046DOI Listing
February 2019

Hydrodynamic modelling of a polluted tropical bay: Assessment of anthropogenic impacts on freshwater runoff and estuarine water renewal.

J Environ Manage 2019 Feb 14;236:695-714. Epub 2019 Feb 14.

Universidad EAFIT, School of Sciences, Department of Earth Sciences, Carrera 49 #7S-50, A.A.3300, Medellín, Colombia.

A bay's capacity to buffer fluvial fluxes between the land and sea is sensitive to hydrological changes that can affect its water renewal rates. In Cartagena Bay, Colombia, pollution issues have been associated with freshwater fluxes which are projected to increase in future years. This has led to plans to reduce freshwater flows by constructing upstream hydraulic doors. Read More

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http://dx.doi.org/10.1016/j.jenvman.2019.01.104DOI Listing
February 2019

Evaluation of the influence of temperature and relative humidity on the permeability of four films to the fumigant dimethyl disulfide.

J Environ Manage 2019 Feb 14;236:687-694. Epub 2019 Feb 14.

State Key Laboratory for Biology of Plant Disease and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China. Electronic address:

Dimethyl disulfide (DMDS) is an alternative fumigant to methyl bromide that was phased out globally due to its stratospheric ozone-depleting properties. Covering the surface of the soil with a plastic tarpaulin or 'barrier film' when using a soil fumigant is typically used to retain fumigants in the soil and to reduce emissions. Emission levels depend on the film's permeability, which varies mainly according to the film's material, the type of fumigant and the environmental conditions. Read More

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http://dx.doi.org/10.1016/j.jenvman.2018.12.075DOI Listing
February 2019

Abating N in Nordic agriculture - Policy, measures and way forward.

J Environ Manage 2019 Feb 14;236:674-686. Epub 2019 Feb 14.

Natural Resources Institute Finland (Luke), Tietotie 4, FI-31600, Jokioinen, Finland.

During the past twenty years, the Nordic countries (Denmark, Sweden, Finland and Norway) have introduced a range of measures to reduce losses of nitrogen (N) to air and to aquatic environment by leaching and runoff. However, the agricultural sector is still an important N source to the environment, and projections indicate relatively small emission reductions in the coming years. The four Nordic countries have different priorities and strategies regarding agricultural N flows and mitigation measures, and therefore they are facing different challenges and barriers. Read More

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http://dx.doi.org/10.1016/j.jenvman.2018.11.143DOI Listing
February 2019

Effects of biochar on bacterial communities in a newly established landfill cover topsoil.

J Environ Manage 2019 Feb 14;236:667-673. Epub 2019 Feb 14.

State Environmental Protection Key Laboratory of Integrated Surface Water-Groundwater Pollution Control, Southern University of Science and Technology, Shenzhen, China; Department of Science and Environmental Studies, The Education University of Hong Kong, Tai Po, Hong Kong, China; Consortium on Health, Environment, Education and Research (CHEER), The Education University of Hong Kong, Tai Po, Hong Kong, China; Guangdong Provincial Key Laboratory of Soil and Groundwater Pollution Control, Southern University of Science and Technology, Shenzhen, China. Electronic address:

Recent studies revealed the benefits of applying biochar in landfill final cover soil, such as adsorbing odorous compounds and promoting microbial methane oxidation. Most of these processes are related to the soil bacterial communities. However, the effects of biochar application on the overall bacterial community in newly established landfill cover soil are not yet understood, especially in field condition. Read More

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http://dx.doi.org/10.1016/j.jenvman.2019.02.010DOI Listing
February 2019

Properties of composts from household food waste produced in automatic composters.

J Environ Manage 2019 Feb 14;236:657-666. Epub 2019 Feb 14.

Department of Power Engineering, Faculty of Mechanical Engineering, VŠB - Technical University of Ostrava, 17. listopadu 15/2172, 708 33, Ostrava-Poruba, Czech Republic. Electronic address:

The minimization of landfill deposition of waste containing biological components represents a big problem, especially in built-up residential areas. The main problem of biologically degradable municipal waste is the quantity and composition of household waste which can have an important influence on decomposition processes already in collecting vessels. An amount of household waste produced in residential areas in the Czech Republic varies from 31 to 337 g/person/day, with an average value of 250 g. Read More

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http://dx.doi.org/10.1016/j.jenvman.2019.02.018DOI Listing
February 2019

Extraction, recovery and characterization of structural extracellular polymeric substances from anammox granular sludge.

J Environ Manage 2019 Feb 14;236:649-656. Epub 2019 Feb 14.

Department of Civil and Environmental Engineering, Polytechnic University of Milan, Via Golgi 39, 20133 Milan, Italy. Electronic address:

The composition and colloidal properties of extracellular polymeric substances (EPS) from anammox granular sludge were investigated through a complete set of spectroscopic and scattering techniques. To fully characterize EPS, we developed a robust and reproducible extraction/recovery protocol specific for anammox biofilms, based on the change of water affinity under alternated alkaline and acidic conditions, each monitored with Z-potential and dynamic light scattering analysis. This method enabled both extraction as a colloidal suspension and recovery as a solid of large amounts of EPS (0. Read More

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http://dx.doi.org/10.1016/j.jenvman.2019.01.054DOI Listing
February 2019

An examination of attributes and barriers to adopt biomass and solar technology. A cross-cultural approach.

J Environ Manage 2019 Feb 14;236:639-648. Epub 2019 Feb 14.

Department Marketing and Market Research. Faculty of Business and Economics. University of Granada, Spain. Electronic address:

This research is primarily aimed at analyzing the most favorable and unfavorable characteristics considered by consumers contemplating the adoption of biomass and solar energy technologies. The pro-environmental behavior, the level of anthropocentrism and ecocentrism in three different cultures are also analyzed using the New Ecological Paradigm scale. Based on a sample of 489 respondents collected by questionnaire, it finds the predominant view in the three cultures is ecocentrism. Read More

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http://dx.doi.org/10.1016/j.jenvman.2019.02.022DOI Listing
February 2019

Removal of metals from mine drainage waters by in situ mineral sorbent-based pilot filter systems.

J Environ Manage 2019 Feb 14;236:631-638. Epub 2019 Feb 14.

Chemical Process Engineering, P.O. Box 4300, FIN-90014, University of Oulu, Oulu, Finland. Electronic address:

Discharge of metal-containing wastewater streams into the environment is an environmental concern because these pollutants do not degrade and tend to bioaccumulate. A number of laboratory-based investigations on the effectiveness of a wide range of filter materials for metal removal from diluted wastewater streams have been reported. However, only a few pilot or full-scale investigations have been conducted. Read More

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http://dx.doi.org/10.1016/j.jenvman.2019.01.115DOI Listing
February 2019

Multifrequency nanoscale impedance microscopy (m-NIM): A novel approach towards detection of selective and subtle modifications on the surface of polycrystalline boron-doped diamond electrodes.

Ultramicroscopy 2019 Feb 8;199:34-45. Epub 2019 Feb 8.

Department of Electrochemistry, Corrosion and Materials Engineering, Faculty of Chemistry, Gdansk University of Technology, Narutowicza 11/12, 80-233 Gdansk, Poland. Electronic address:

In this paper, we describe the modification of Nanoscale Impedance Microscopy (NIM), namely, a combination of contact-mode atomic force microscopy with local impedance measurements. The postulated approach is based on the application of multifrequency voltage perturbation instead of standard frequency-by-frequency analysis, which among others offers more time-efficient and accurate determination of the resultant impedance spectra with high spatial resolution. Based on the impedance spectra analysis with an appropriate electric equivalent circuit, it was possible to map surface resistance and contact capacitance. Read More

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http://dx.doi.org/10.1016/j.ultramic.2019.01.004DOI Listing
February 2019

Potentially toxic elements (PTEs) and polycyclic aromatic hydrocarbons (PAHs) in fish and prawn in the Persian Gulf, Iran.

Ecotoxicol Environ Saf 2019 Feb 14;173:251-265. Epub 2019 Feb 14.

Khorramshahr Environmental Protection Office, Khorramshahr 6491846783, Iran.

This study aimed to speciate and quantify potentially toxic elements (PTEs) and polycyclic aromatic hydrocarbons (PAHs), in addition to estimate potential human health risk of PTEs (As, Cd, Co, Cr, Cu, Hg, Mn, Ni, Pb, Se, V, and Zn) through the consumption of three edible fish species (Leuciscus vorax, Liza abu, and Coptodon zillii) and two prawn species (Metapenaeus affinis and Penaeus semisulcatus) collected from Arvand River and Musa Estuary in the Persian Gulf. The concentration of As in prawn species exceeded permissible limit set by international organizations. PAHs were dominated by low molecular weight species such as naphthalene, phenanthrene, and, fluorene but generally exhibited low mean concentrations in fish and prawn samples. Read More

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http://dx.doi.org/10.1016/j.ecoenv.2019.02.005DOI Listing
February 2019

N-acetylcysteine alleviated bisphenol A-induced testicular DNA hypermethylation of rare minnow (Gobiocypris rarus) by increasing cysteine contents.

Ecotoxicol Environ Saf 2019 Feb 14;173:243-250. Epub 2019 Feb 14.

College of Animal Science and Technology, Northwest A&F University, Shaanxi Key Laboratory of Molecular Biology for Agriculture, Yangling, Shaanxi 712100, China. Electronic address:

Ubiquitous BPA exposure resulted in DNA methylation errors and oxidative stress. Numerous studies have demonstrated that oxidative stress can lead to changes in DNA methylation levels and supplementation with antioxidants, including N-acetylcysteine (NAC), was able to restore these changes. Our previous study supposed that BPA-induced de novo synthesis of glutathione (GSH) promoted DNA methylation process in Gobiocypris rarus testes. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01476513193018
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http://dx.doi.org/10.1016/j.ecoenv.2019.02.035DOI Listing
February 2019
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The effects of EDTA on plant growth and manganese (Mn) accumulation in Polygonum pubescens Blume cultured in unexplored soil, mining soil and tailing soil from the Pingle Mn mine, China.

Ecotoxicol Environ Saf 2019 Feb 14;173:235-242. Epub 2019 Feb 14.

Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Guangxi Normal University), the Ministry of Education, China; College of Life Science, Guangxi Normal University, 541004 Guilin, China. Electronic address:

The effects of water-extractable Mn concentration, bioaccumulation factor (BAF), translocation factor (TF), and Mn uptake by Polygonum pubescens Blume cultured in the unexplored soil, mining soil and tailing soil from the Pingle Mn mine in China were quantified in a pot experiment to determine the effects of EDTA exposure on the success of phytoremediation. The results showed that EDTA significantly (P < 0.05) increased the water-extractable Mn concentration, and soils with different amounts of artificial disturbances had different responses to EDTA exposure. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01476513193011
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http://dx.doi.org/10.1016/j.ecoenv.2019.01.086DOI Listing
February 2019
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Antioxidative enzymes activity and thiol metabolism in three leafy vegetables under Cd stress.

Ecotoxicol Environ Saf 2019 Feb 14;173:214-224. Epub 2019 Feb 14.

Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China.

The enrichment of Cadmium in vegetables is threatening human health. The study aimed to screen Cd low-enriched leafy vegetables and explore whether antioxidative enzymes and heavy metal chelators are synergistic defensive mechanisms. In this paper, the Cd accumulation and translocation of garland chrysanthemum (Chrysanthemum coronarium L. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01476513193017
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http://dx.doi.org/10.1016/j.ecoenv.2019.02.026DOI Listing
February 2019
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The defense system for Bidens pilosa root exudate treatments in Pteris multifida gametophyte.

Ecotoxicol Environ Saf 2019 Feb 14;173:203-213. Epub 2019 Feb 14.

Stockbridge School of Agriculture, University of Massachusetts, Amherst, MA 01003, USA.

According to the novel weapons hypothesis, root exudates are the inhibition factors for native species growth and development through invasive plants. It is hypothesized that antioxidant system (AOS) presents an effective role in plant defense system. The allelopathy indexes of P. Read More

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http://dx.doi.org/10.1016/j.ecoenv.2019.01.097DOI Listing
February 2019

The occurrence, potential toxicity, and toxicity mechanism of bisphenol S, a substitute of bisphenol A: A critical review of recent progress.

Ecotoxicol Environ Saf 2019 Feb 14;173:192-202. Epub 2019 Feb 14.

Guangdong Provincial Key Laboratory of Soil and Groundwater Pollution Control, School of Environmental Science and Engineering, Southern University of Science and Technology, Shenzhen 518055, China; State Environmental Protection Key Laboratory of Integrated Surface Water-Groundwater Pollution Control, School of Environmental Science and Engineering, Southern University of Science and Technology, Shenzhen 518055, China. Electronic address:

Bisphenol S (BPS) has been introduced into the industry as a safer alternative to bisphenol A (BPA). The distribution of BPS has recently become an important issue worldwide, but investigations on the toxicity and mechanisms of BPS remain limited. A review of the literature reveals that BPS has widespread presence in environmental media, such as indoor dust, surface water, sediments, and sewage sludge. Read More

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http://dx.doi.org/10.1016/j.ecoenv.2019.01.114DOI Listing
February 2019

Effects of biochar and zeolite soil amendments with foliar proline spray on nickel immobilization, nutritional quality and nickel concentrations in wheat.

Ecotoxicol Environ Saf 2019 Feb 14;173:182-191. Epub 2019 Feb 14.

Department of Bioinformatics and Biotechnology, Government College University, Faisalabad 38000, Pakistan. Electronic address:

Since Ni-rich soils are a threat to the environment, growing edible crops on Ni-rich soils can pose a serious risk to human, animal, plant and ecosystem health and, hence, is considered as a challenging task for the researchers. Contrarily, limiting the bioavailability of Ni in such soils upon the addition of suitable amendments cum foliar spray of proteinogenic amino acids having an objective to alleviate stress to crop plants can considerably reduce the environmental risk. In this pot trail, we substantiate the effects of biochar (BR) and zeolite (ZL) addition in the soil along with proline (PN) spray on the resistance, and stress responses of wheat against Ni as well as on Ni translocation and accumulation in wheat plants grown on a Ni-rich soil contaminated by electroplating effluent. Read More

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http://dx.doi.org/10.1016/j.ecoenv.2019.02.025DOI Listing
February 2019

Effects of gemfibrozil on sex hormones and reproduction related performances of Oryzias latipes following long-term (155 d) and short-term (21 d) exposure.

Ecotoxicol Environ Saf 2019 Feb 14;173:174-181. Epub 2019 Feb 14.

School of Public Health, Seoul National University, Seoul 08826, Republic of Korea. Electronic address:

Gemfibrozil, a lipid-regulating pharmaceutical, has been widely used for treating dyslipidemia in humans and detected frequently in freshwater environments. Since plasma cholesterol is a precursor of steroid hormones, the use of gemfibrozil may influence the sex hormone balances. However, its endocrine toxicity following long-term exposure is not well understood. Read More

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http://dx.doi.org/10.1016/j.ecoenv.2019.02.015DOI Listing
February 2019

Remediation of Cd- and Pb- contaminated clay soils through combined freeze-thaw and soil washing.

J Hazard Mater 2019 Feb 11;369:87-95. Epub 2019 Feb 11.

Department of Civil and Environmental Engineering, Setsunan University, Osaka 5728508, Japan.

To improve the washing efficiency for low-permeability clay, the method of freeze-thaw synergistic chemical washing was put forward to study the cadmium (Cd)-and lead (Pb)- real-site contaminated soils as the research object and ethylene diaminete traacetic acid (EDTA) was selected as the eluent to conduct a soil column washing test of heavy metal-contaminated clay soil. Results show that repeated freeze-thaw of soil can destroy the original structure of soil particles, help the eluent fully interact with pollutants, and thus improve washing efficiency. Cd was showed the best removal effect after supplying 0. Read More

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http://dx.doi.org/10.1016/j.jhazmat.2019.02.038DOI Listing
February 2019

Shock initiation of multi-component insensitive PBX explosives: Experiments and MC-DZK mesoscopic reaction rate model.

J Hazard Mater 2019 Feb 10;369:62-69. Epub 2019 Feb 10.

The State Key Laboratory of Explosion Science and Technology, Beijing Institute of Technology, Beijing, 100081, China.

To facilitate the pre-estimation and optimization of the prescription design of a multi-component polymer bonded explosive (PBX), a multicomponent mesoscopic reaction rate model (MC-DZK model) is developed to predicate preferably the influence of both the explosive components and the particle size of on the shock initiation. All the parameters in the model are determined directly by the parameters in the DZK model for each explosive component. Furthermore, for the multicomponent insensitive explosive PBXC10 (70% TATB, 25% HMX, and 5% Kel-F800 by weight) with different explosive particle sizes, both shock initiation experiments and corresponding numerical simulations are performed, and there is satisfactory agreement between the numerical results and the available experimental data. Read More

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http://dx.doi.org/10.1016/j.jhazmat.2019.02.028DOI Listing
February 2019

Persistent Na influx drives L-type channel resting Ca entry in rat melanotrophs.

Cell Calcium 2019 Feb 6;79:11-19. Epub 2019 Feb 6.

Laboratory of Veterinary Physiology, Joint Department of Veterinary Medicine, Faculty of Agriculture, Tottori University, Tottori, Japan; The United Graduate School of Veterinary Science, Yamaguchi University, Yamaguchi, Japan. Electronic address:

Rat melanotrophs express several types of voltage-gated and ligand-gated calcium channels, although mechanisms involved in the maintenance of the resting intracellular Ca concentration ([Ca]) remain unknown. We analyzed mechanisms regulating resting [Ca] in dissociated rat melanotrophs by Ca-imaging and patch-clamp techniques. Treatment with antagonists of L-type, but not N- or P/Q-type voltage-gated Ca channels (VGCCs) as well as removal of extracellular Ca resulted in a rapid and reversible decrease in [Ca], indicating constitutive Ca influx through L-type VGCCs. Read More

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http://dx.doi.org/10.1016/j.ceca.2019.02.001DOI Listing
February 2019

Net-societal and net-private benefits of some existing vehicle crash avoidance technologies.

Accid Anal Prev 2019 Feb 14;125:207-216. Epub 2019 Feb 14.

Civil and Environmental Engineering, Carnegie Mellon University, Porter Hall 103, 5000 Forbes Avenue, Pittsburgh, PA 15213, USA. Electronic address:

Most light-duty vehicle crashes occur due to human error. Many of these crashes could be avoided or made less severe with the aid of crash avoidance technologies. These technologies can assist the driver in maintaining control of the vehicle when a possibly dangerous situation arises by issuing alerts to the driver and in a few cases, responding to the situation itself. Read More

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http://dx.doi.org/10.1016/j.aap.2019.02.003DOI Listing
February 2019

Late mortality and causes of death among 5-year survivors of childhood cancer diagnosed in the period 1960-1999 and registered in the Italian Off-Therapy Registry.

Eur J Cancer 2019 Feb 14;110:86-97. Epub 2019 Feb 14.

Epidemiology and Biostatistics Unit, IRCCS Istituto Giannina Gaslini, Genova, Italy. Electronic address:

Introduction: Advances in paediatric oncology led to the increase in long-term survival, revealing the burden of therapy-related long-term side effects. We evaluated overall and cause-specific mortality in a large cohort of Italian childhood cancer survivors (CCSs) and adolescent cancer survivors identified through the off-therapy registry.

Materials And Methods: CCSs alive 5 years after cancer diagnosis occurring between 1960 and 1999 were eligible; the last follow-up was between 2011 and 2014. Read More

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http://dx.doi.org/10.1016/j.ejca.2018.12.021DOI Listing
February 2019

Highly synergistic effects on ammonium removal by the co-system of Pseudomonas stutzeri XL-2 and modified walnut shell biochar.

Bioresour Technol 2019 Feb 8;280:239-246. Epub 2019 Feb 8.

Key Laboratory of the Three Gorges Reservoir Region's Eco-Environment, Ministry of Education, Chongqing University, Chongqing 400045, PR China.

Pseudomonas stutzeri strain XL-2 presented efficient ammonium removal due to heterotrophic nitrification-aerobic denitrification. The modified walnut shell biochar also showed ammonium adsorption due to chemical interaction. The complex of modified biochar and strain XL-2 exhibited excellent synergistic effects on ammonium removal, especially in unfavorable environment. Read More

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http://dx.doi.org/10.1016/j.biortech.2019.02.037DOI Listing
February 2019

Radon in groundwater baseline study prior to unconventional shale gas development and hydraulic fracturing in the Karoo Basin (South Africa).

Appl Radiat Isot 2019 Feb 7;147:7-13. Epub 2019 Feb 7.

Military Academy, Stellenbosch University, Private Bag X2, Saldanha, 7395, South Africa.

The prospect of unconventional shale gas development in the semi-arid Karoo Basin (South Africa) has created the prerequisite to temporally characterise the natural radioactivity in associated groundwater which is solely depended on for drinking and agriculture purposes. Radon (Rn) was the primary natural radionuclide of interest in this study; however, supplementary radium (Ra and Ra) in-water measurements were also conducted. A total of 53 aquifers spanning three provinces were studied during three separate measurement campaigns from 2014 to 2016. Read More

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http://dx.doi.org/10.1016/j.apradiso.2019.02.006DOI Listing
February 2019

The peculiar aging of human liver: A geroscience perspective within transplant context.

Ageing Res Rev 2019 Feb 14. Epub 2019 Feb 14.

Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy; CIG-Interdepartmental Center "Galvani", University of Bologna, Bologna, Italy; CSR-Centro di Studio per la Ricerca dell'Invecchiamento, University of Bologna, Bologna, Italy.

An appraisal of recent data highlighting aspects inspired by the new Geroscience perspective are here discussed. The main findings are summarized as follows: i) liver has to be considered an immunological organ, and new studies suggest a role for the recently described cells named telocytes; ii) the liver-gut axis represents a crucial connection with environment and life style habits and may influence liver diseases onset; iii) the physiological aging of liver shows relatively modest alterations. Nevertheless, several molecular changes appear to be relevant: a) an increase of microRNA-31-5p; -141-3p; -200c-3p expressions after 60 years of age; b) a remodeling of genome-wide DNA methylation profile evident until 60 years of age and then plateauing; c) changes in transcriptome including the metabolic zones of hepatocyte lobules; d) liver undergoes an accelerated aging in presence of chronic inflammation/liver diseases in a sort of continuum, largely as a consequence of unhealthy life styles and exposure to environmental noxious agents. Read More

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http://dx.doi.org/10.1016/j.arr.2019.02.002DOI Listing
February 2019

Microbial transformation of chiral organohalides: Distribution, microorganisms and mechanisms.

J Hazard Mater 2019 Jan 31;368:849-861. Epub 2019 Jan 31.

School of Environmental Science and Engineering, Sun Yat-Sen University, 510275 Guangzhou, China; Environmental Microbiome Research Center, Sun Yat-Sen University, 510275 Guangzhou, China; Guangdong Provincial Key Laboratory of Environmental Pollution Control and Remediation Technology, 510275 Guangzhou, China. Electronic address:

Chiral organohalides including dichlorodiphenyltrichloroethane (DDT), Hexabromocyclododecane (HBCD) and polychlorinated biphenyls (PCBs) raise a significant concern in the environmental occurrence, fate and ecotoxicology due to their enantioselective biological effects. This review provides a state-of-the-art overview on enantioselective microbial transformation of the chiral organohalides. We firstly summarized worldwide field assessments of chiral organohalides in a variety of environmental matrices, which suggested the pivotal role of microorganisms in enantioselective transformation of chiral organohalides. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03043894193011
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http://dx.doi.org/10.1016/j.jhazmat.2019.01.103DOI Listing
January 2019
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Receptive and productive speech and language abilities in hearing-impaired children with German as a second language.

Int J Pediatr Otorhinolaryngol 2019 Feb 6;120:100-107. Epub 2019 Feb 6.

University of Applied Sciences, Alter Teichweg 19, 22081, Hamburg, Germany. Electronic address:

Objectives: Many studies examining early bilingualism in migrant populations focus on the development of the first language. As language acquisition is closely related to the hearing development, there is a critical need to investigate language development in hearing-impaired children being raised bilingually who were fitted with cochlear implants and/or hearing aids. Therefore, this research project aimed to study the linguistic development of hearing-impaired children being raised with German as a second language who were provided with hearing aids or cochlear implants. Read More

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http://dx.doi.org/10.1016/j.ijporl.2019.02.012DOI Listing
February 2019

Clustered risk: An ecological understanding of sexual activity among adolescent boys and girls in two urban slums in Monrovia, Liberia.

Soc Sci Med 2019 Feb 8;224:106-115. Epub 2019 Feb 8.

Department of Social and Behavioral Sciences, Harvard TH Chan School of Public Health, Division of Adolescent and Young Adult Medicine, Boston Children's Hospital, 677 Huntington Avenue, Boston, MA, 02115, USA. Electronic address:

Many young people experience sexual debut before they are able to manage risk in order to avoid adverse consequences. Gender norms, social position, and power can undermine an adolescent's ability to exercise agency in their first sexual encounters and negotiate safer sexual behavior. This study examines the intersection of psychosocial and interpersonal factors with the social and physical environment to form an ecological understanding of how the determinants that shape sexual activity differ between boys and girls in two urban slums in Monrovia, Liberia. Read More

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http://dx.doi.org/10.1016/j.socscimed.2019.02.010DOI Listing
February 2019
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