2,155,689 results match your criteria Environmental and Ecological Statistics [Journal]
J Vet Sci 2018 Dec 4. Epub 2018 Dec 4.
Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata, Anthrax Reference Institute of Italy, Foggia 71121, Italy.
Anthrax, caused by , is a non-contagious infectious disease that affects a wide range of animal species (primarily ruminants), as well as humans. Due to the often fatal outcome in human cases, the quick administration of definitely effective antimicrobials is crucial either as prophylaxis or for the therapy of clinical cases. In this study, a total of 110 strains, temporally, geographically and genetically different, isolated during anthrax outbreaks in Italy from 1984 to 2017, were screened for their susceptibility towards 16 clinically relevant antimicrobial agents using the broth microdilution method. Read More
Nucleic Acids Res 2018 Dec 12. Epub 2018 Dec 12.
School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Alternative splicing is a key feature of human genes, yet studying its regulation is often complicated by large introns. The Down Syndrome Cell Adhesion Molecule (Dscam) gene from Drosophila is one of the most complex genes generating vast molecular diversity by mutually exclusive alternative splicing. To resolve how alternative splicing in Dscam is regulated, we first developed plasmid-based UAS reporter genes for the Dscam variable exon 4 cluster and show that its alternative splicing is recapitulated by GAL4-mediated expression in neurons. Read More
J Biochem 2018 Dec 12. Epub 2018 Dec 12.
Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DISTABIF), University of Campania 'Luigi Vanvitelli', Via Vivaldi 43, Caserta, Italy.
Here, we report the amino acid sequence of Ageritin, the first ribotoxin-like protein from basidiomycetes (Agrocybe aegerita). This protein consists of 135 amino acid residues with a theoretical molecular mass of 14801.80 Da (experimental mass 14802. Read More
J Biochem 2018 Dec 12. Epub 2018 Dec 12.
Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan.
Males and females share the same genetic code, but gene expression profile often displays differences between two sexes. Mouse embryonic fibroblasts (MEFs) have been used to experiment as a useful tool to test gene function. They have also been characterized by gender-based differences in expressed genes such as Y-linked Sry or X-linked Hprt. Read More
ILAR J 2018 Dec 12. Epub 2018 Dec 12.
Department of Radiology, Miller Research Building Molecular Imaging Service Center, Johns Hopkins University, Baltimore, Maryland.
Preclinical noninvasive imaging can be an indispensable tool for studying animal models of disease. In vivo imaging to assess anatomical, functional, and molecular features requires verification by a comparison to the macroscopic and microscopic morphological features, since all noninvasive in vivo imaging methods have much lower resolution than standard histopathology. Comprehensive pathological evaluation of the animal model is underutilized; yet, many institutions have veterinary or human pathologists with necessary comparative pathology expertise. Read More
Ann Bot 2018 Dec 12. Epub 2018 Dec 12.
Department of Botany, Faculty of Science, University of South Bohemia, Branišovská, Ceské Budejovice, Czech Republic.
Background And Aims: Polyploidy has played an important role in the evolution of ferns. However, the dearth of data on cytotype diversity, cytotype distribution patterns and ecology in ferns is striking in comparison with angiosperms and prevents an assessment of whether cytotype coexistence and its mechanisms show similar patterns in both plant groups. Here, an attempt to fill this gap was made using the ploidy-variable and widely distributed Cystopteris fragilis complex. Read More
Ann Bot 2018 Dec 12. Epub 2018 Dec 12.
University of Vienna, Department of Botany and Biodiversity Research, Rennweg, Vienna, Austria.
Background And Aims: Phylogenetic relationships within tribe Shoreeae, containing the main elements of tropical forests in Southeast Asia, present a long-standing problem in the systematics of Dipterocarpaceae. Sequencing whole plastomes using next-generation sequencing- (NGS) based genome skimming is increasingly employed for investigating phylogenetic relationships of plants. Here, the usefulness of complete plastid genome sequences in resolving phylogenetic relationships within Shoreeae is evaluated. Read More
Ann Bot 2018 Dec 12. Epub 2018 Dec 12.
Institute of Botany, The Czech Academy of Sciences, Průhonice, Czech Republic.
Background And Aims: Alpine cushion plants can initially facilitate other species during ecological succession, but later on can be negatively affected by their development, especially when beneficiaries possess traits allowing them to overrun their host. This can be reinforced by accelerated warming favouring competitively strong species over cold-adapted cushion specialists. However, little empirical research has addressed the trait-based mechanisms of these interactions. Read More
J Natl Cancer Inst 2018 Dec 12. Epub 2018 Dec 12.
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Background: Genome-wide association studies (GWAS) identify associations of individual single-nucleotide polymorphisms (SNPs) with cancer risk but usually only explain a fraction of the inherited variability. Pathway analysis of genetic variants is a powerful tool to identify networks of susceptibility genes.
Methods: We conducted a large agnostic pathway-based meta-analysis of GWAS data using the summary-based adaptive rank truncated product method to identify gene sets and pathways associated with pancreatic ductal adenocarcinoma (PDAC) in 9040 cases and 12 496 controls. Read More
Hum Reprod Update 2018 Dec 12. Epub 2018 Dec 12.
Priority Research Centre for Reproductive Science, Discipline of Biological Sciences, University of Newcastle, Callaghan, NSW, Australia.
Background: DNA integrity and stability are critical determinants of cell viability. This is especially true in the female germline, wherein DNA integrity underpins successful conception, embryonic development, pregnancy and the production of healthy offspring. However, DNA is not inert; rather, it is subject to assault from various environment factors resulting in chemical modification and/or strand breakage. Read More
Int J Epidemiol 2018 Dec 11. Epub 2018 Dec 11.
Population Health Sciences, University of Bristol, Bristol, UK.
Background: Accumulating evidence suggests that breastfeeding benefits children's intelligence, possibly due to long-chain polyunsaturated fatty acids (LC-PUFAs) present in breast milk. Under a nutritional adequacy hypothesis, an interaction between breastfeeding and genetic variants associated with endogenous LC-PUFAs synthesis might be expected. However, the literature on this topic is controversial. Read More
ILAR J 2018 Dec 12. Epub 2018 Dec 12.
Unit for Laboratory Animal Medicine, University of Michigan Medical School in Ann Arbor, Michigan.
Research using laboratory animals has been revolutionized by the creation of humanized animal models, which are immunodeficient animals engrafted with human cells, tissues, or organs. These animal models provide the research community a unique and promising opportunity to mimic a wide variety of disease conditions in humans, from infectious disease to cancer. A vast majority of these models are humanized mice like those injected with human CD34+ hematopoietic stem cells and patient-derived xenografts. Read More
J Phys Condens Matter 2018 Dec 12. Epub 2018 Dec 12.
Advanced Computing and Simulation Laboratory, Monash University, Clayton,, Victoria 3800, Melbourne, Victoria, 3800, AUSTRALIA.
A hybrid nanostructure where a graphene nanoflake (GNF) is optically coupled to a carbon nanotube (CNT) could potentially possess enhanced sensing capabilities compared to the individual constituents whilst inheriting their high biocompatibility, favourable electrical, mechanical and spectroscopic properties. Therefore, in this paper, we investigate the scattering characteristics of an all-carbon exciton-plasmon nanohybrid which was made by coupling an elliptical GNF resonator to a semiconducting CNT gain element. We analytically model the nanohybrid as an open quantum system using cavity quantum electrodynamics. Read More
Bioelectrochemistry 2018 Dec 1;126:105-112. Epub 2018 Dec 1.
McGill University, Bioresource Engineering Department, 21111 Lakeshore Rd., Ste-Anne-de-Bellevue, QC H9X 3V9, Canada; National Research Council of Canada, 6100 Royalmount Ave, Montreal, QC H4P 2R2, Canada. Electronic address:
This study compares the biosensing performance of a microbial fuel cell (MFC) and a microbial electrolysis cell (MEC). Initial tests provided a qualitative comparison of MFC and MEC currents after the anode compartment liquid (anolyte) was spiked with acetate, or sulphates of NH, Na, Mg, Fe, or a fertilizer solution. Current measurements showed that the MFC sensor had a faster response time, higher sensitivity, and faster recovery time after the spike. Read More
Colloids Surf B Biointerfaces 2018 Dec 5;175:239-247. Epub 2018 Dec 5.
Laboratory of Environmental Sciences and Technology, Xinjiang Technical Institute of Physics & Chemistry, Chinese Academy of Sciences, Urumqi, Xinjiang 830011, China; Shanghai Institute of Pollution Control and Ecological Security, Shanghai 200092, China. Electronic address:
Chemotherapy is an important first-line strategy for tumor therapy in cancer treatment, but multidrug resistance (MDR) is a major problem that reduces the efficacy of chemotherapeutics. Herein, we report a novel photothermally controlled intelligent drug release system (AuNP@mSiO-DOX-FA) with a large amount of drugs loading for synergistic chemo-photothermal therapy of MDR in breast cancer. The nanoplatform utilized gold nanoparticles as a hyperthermia core, and large-mesoporous silica as a shell for doxorubicin (DOX) loading. Read More
Cell Rep 2018 Dec;25(11):3194-3203.e4
Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address:
5-hydroxymethylcytosine (5hmC) is enriched in brain and has been recognized as an important DNA modification. However, the roles of 5hmC and its writers, ten-eleven translocation (Tet) proteins, in stress-induced response have yet to be elucidated. Here, we show that chronic restraint stress (CRS) induced depression-like behavior in mice and resulted in a 5hmC reduction in prefrontal cortex (PFC). Read More
Ann Am Thorac Soc 2018 Dec 12. Epub 2018 Dec 12.
Brigham and Women's Hospital, Medicine, Boston, Massachusetts, United States.
Telomeres are repetitive nucleotide sequences that cap linear chromosomes, thereby limiting progressive chromosomal shortening during cell replication. In conjunction with environmental factors, common single nucleotide polymorphisms and rare and ultra-rare telomere-related mutations are associated with accelerated telomere shortening resulting in organ dysfunction, including interstitial lung disease (ILD). The most common telomere-related mutation-associated ILD is idiopathic pulmonary fibrosis (IPF). Read More
Am J Respir Cell Mol Biol 2018 Dec 12. Epub 2018 Dec 12.
University of Tokushima Graduate School, Respiratory Medicine and Rheumatology, Tokushima, Japan ;
The signaling pathways of growth factors including platelet-derived growth factor (PDGF) can be considered specific targets for overcoming the poor prognosis of idiopathic pulmonary fibrosis (IPF). Nintedanib, the recently approved multiple kinase inhibitor, has shown promising anti-fibrotic effects in IPF patients; however, its efficacy is still limited, and in some cases, treatment discontinuation is necessary due to toxicities such as gastrointestinal disorders. Therefore, more effective agents with less toxicity are still needed. Read More
Nano Lett 2018 Dec 12. Epub 2018 Dec 12.
Pt nanoparticles play an essential role in a wide variety of catalytic reactions. The activity of the particles strongly depends on their three-dimensional (3D) structure and exposed facets, as well as on the reactive environment. High resolution electron microscopy has often been used to characterize nanoparticle catalysts, but unfortunately, most observations so far have been either performed in vacuum and/or using conventional (2D) in situ microscopy. Read More
PLoS One 2018 12;13(12):e0208978. Epub 2018 Dec 12.
Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, Ontario, Canada.
An increasing number of antibody-based therapies are being considered for controlling bacterial infections, including Clostridium difficile by targeting toxins A and B. In an effort to develop novel C. difficile immunotherapeutics, we previously isolated several single-domain antibodies (VHHs) capable of toxin A neutralization through recognition of the extreme C-terminal combined repetitive oligopeptides (CROPs) domain, but failed at identifying neutralizing VHHs that bound a similar region on toxin B. Read More
PLoS One 2018 12;13(12):e0208995. Epub 2018 Dec 12.
School of Environmental Sciences, University of Liverpool, Liverpool, United Kingdom.
Marine ecosystems are heavily influenced by a wide range of human-related impacts, and thus monitoring is essential to preserve and manage these sensitive habitats. Seabirds are considered important bioindicators of the oceans, but accessing breeding populations can be difficult, expensive and time consuming. New technologies have been employed to facilitate data collection on seabirds that can reduce costs and minimize disturbance. Read More
PLoS One 2018 12;13(12):e0208945. Epub 2018 Dec 12.
U. S. Department of Agriculture, Agricultural Research Service, Beltsville Agricultural Research Center, Environmental Microbiology and Food Safety Laboratory, Beltsville, Maryland, United States of America.
Water conservation and economics dictate that fresh produce processors reuse/recirculate the process water. However, the ensuing accumulation of organic matter in water depletes the chlorine sanitizer required for food safety. In this study, we comprehensively investigated chemical compounds that are responsible for water quality in relation to chemical oxygen demand (COD) and chlorine demand (CLD), the two most critical factors associated with water treatment and chlorine replenishment. Read More
PLoS One 2018 12;13(12):e0208560. Epub 2018 Dec 12.
Forest Resources and Environmental Science, Michigan Technological University, Houghton, MI, United States of America.
Using time-series transcriptomic data from poplar roots undergoing polyethylene glycol (PEG)-induced drought stress, we built a genetic network model of the involved putative molecular responses. We found that the network resembled a hierarchical structure. The highest hierarchical level in this structure is occupied by 9 genes, which we called superhubs because they were primarily connected to 18 hub genes, which are then connected to 2,934 terminal genes. Read More
PLoS One 2018 12;13(12):e0209013. Epub 2018 Dec 12.
Fort Collins Science Center, U.S. Geological Survey, Fort Collins, Colorado, United States of America.
How information is communicated influences the public's environmental perceptions and behaviors. Information channels and sources both play an important role in the dissemination of information. Trust in a source is often used as a proxy for whether a particular piece of information is credible. Read More
PLoS One 2018 12;13(12):e0209022. Epub 2018 Dec 12.
Karlsruhe Institute of Technology, Institute of Meteorology and Climate Research - Atmospheric Environmental Research, Garmisch-Partenkirchen, Germany.
It has been hypothesized that the energy balance closure problem of single-tower eddy-covariance measurements is linked to large-scale turbulent transport. In order to shed light on this problem, we investigate the functional dependence of the normalized residual for the potential temperature and humidity conservation equations, i.e. Read More
PLoS One 2018 12;13(12):e0208950. Epub 2018 Dec 12.
Centre for Behavioural Research in Cancer, Cancer Council Victoria, Melbourne, Australia.
Background: Social denormalisation of smoking can provide an environment that helps smokers to quit. This study examined which of three measures of anti-smoking social norms have the greatest influence on quitting-related cognitions and behaviours, and if this influence differs according to socioeconomic status (SES).
Methods: The Victorian Tracking Survey measured social norms among 1,348 (n(weighted) = 1,373) Australian adult smokers (aged 18-59) between 2012 and 2014, who were followed-up one week later. Read More
PLoS One 2018 12;13(12):e0208621. Epub 2018 Dec 12.
Spatial Epidemiology and Ecology Research Laboratory, Department of Geography, University of Florida, Gainesville, Florida, United States of America.
Quantitative models describing environmentally-mediated disease transmission rarely focus on the independent contribution of recruitment and the environment on the force of infection driving outbreaks. In this study we attempt to investigate the interaction between external factors and host's population dynamics in determining the outbreaks of some indirectly transmitted diseases. We first built deterministic and stochastic compartmental models based on anthrax which were parameterized using information from literature and complemented with field observations. Read More
PLoS One 2018 12;13(12):e0207954. Epub 2018 Dec 12.
Division of Bacteriology, Indian Council of Medical Research-National Institute of Cholera and Enteric Diseases, Kolkata, West Bengal, India.
Salmonella enterica serovar Typhimurium (S. Typhimurium) is a common serovar associated with non-typhoidal salmonellosis globally. However, there is insufficient data on molecular characterization of S. Read More
PLoS One 2018 12;13(12):e0207936. Epub 2018 Dec 12.
Department of Biology, Stanford University, Stanford, California, United States of America.
Species are shifting their ranges due to climate change, many moving to cooler and higher locations. However, with elevation increase comes oxygen decline, potentially limiting a species' ability to track its environment depending on what mechanisms it has available to compensate for hypoxic stress. Pikas (Family Ochotonidae), cold-specialist small mammal species, are already undergoing elevational range shifts. Read More
PLoS One 2018 12;13(12):e0208535. Epub 2018 Dec 12.
Department of Zoology, Institute of Ecology and Earth Sciences, University of Tartu, Vanemuise, Tartu, Estonia.
Finding standard cost-effective methods for monitoring biodiversity is challenging due to trade-offs between survey costs (including expertise), specificity, and range of applicability. These trade-offs cause a lack of comparability among datasets collected by ecologists and conservationists, which is most regrettable in taxonomically demanding work on megadiverse inconspicuous taxon groups. We have developed a site-scale survey method for diverse sessile land organisms, which can be analyzed over multiple scales and linked with ecological insights and management. Read More
PLoS One 2018 12;13(12):e0208272. Epub 2018 Dec 12.
Department of Evolutionary Biology, Ecology and Environmental Sciences, Faculty of Biology, University of Barcelona, Barcelona, Spain.
The study of leaf litter as a resource for shredders has emerged as a key topic in trophic links in ecology. However, thus far, most studies have emphasized the leaf quality as one of the main determinants of shredder behaviour and growth without simultaneously considering the leaf quantity availability. Nevertheless, the combined effects of leaf quantity and quality on shredder behaviour and growth is particularly crucial to further understand how ecosystem functioning may respond to the increasing flow intermittency due to climate change. Read More
PLoS One 2018 12;13(12):e0208223. Epub 2018 Dec 12.
Desert Agriculture Initiative, King Abdullah University of Science and Technology (KAUST), Biological and Environmental Sciences and Engineering Division (BESE), Thuwal, Kingdom of Saudi Arabia.
Deserts, such as those found in Saudi Arabia, are one of the most hostile places for plant growth. However, desert plants are able to impact their surrounding microbial community and select beneficial microbes that promote their growth under these extreme conditions. In this study, we examined the soil, rhizosphere and endosphere bacterial communities of four native desert plants Tribulus terrestris, Zygophyllum simplex, Panicum turgidum and Euphorbia granulata from the Southwest (Jizan region), two of which were also found in the Midwest (Al Wahbah area) of Saudi Arabia. Read More
PLoS One 2018 12;13(12):e0207640. Epub 2018 Dec 12.
Graduate Institute of Environmental Education, National Taiwan Normal University, Taipei City, Taiwan, ROC.
Terrestrial hermit crabs play a significant role in coastal ecology. For example, as seed dispersers and debris scavengers in coastal forests, they accelerate the decomposition of organic substances. In the Indo-Pacific Ocean, Coenobita rugosus, C. Read More
PLoS One 2018 12;13(12):e0207161. Epub 2018 Dec 12.
School of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, United States of America.
The success of Staphylococcus aureus as a pathogen is due in part to its ability to adapt to changing environmental conditions using signal transduction pathways, such as metabolite- responsive regulators and two-component systems. S. aureus has a two-component system encoded by the gene pair sav0224 (hptS) and sav0223 (hptR) that regulate the hexose phosphate transport (uhpT) system in response to extracellular glucose-6-phosphate. Read More
PLoS One 2018 12;13(12):e0207394. Epub 2018 Dec 12.
University of Science and Technology of China, Hefei, Anhui, China.
Background: The tension in doctor-patient relationships is becoming progressively greater due to the high expectations of patients and the physicians' work pressure. Recent studies have addressed factors which affect the tension of doctor-patient relationships, and our study continues this trend by looking at the influence of resiliency and physician trust in the patient (PTP), that is, how much the doctor trusts the patient.
Methods: Based on a survey of 329 physicians, a descriptive analysis of measured data was done using SPSS 19. Read More
PLoS One 2018 12;13(12):e0207783. Epub 2018 Dec 12.
Department of Environmental Sciences, University of Toledo, Toledo, OH, United States of America.
In the past few years, miniature light-level geolocators have been developed for tracking wild bird species that were previously too small to track during their full annual cycle. Geolocators offer an exciting opportunity to study the full annual cycle for many species. However, the potential detrimental effects of carrying geolocators are still poorly understood, especially for small-bodied birds. Read More
PLoS One 2018 12;13(12):e0207359. Epub 2018 Dec 12.
Defence Institute of Physiology and Allied Sciences, Defence Research and Development Organization, Timarpur, Delhi, India.
Seasonal and human physiological changes are important factors in the development of many diseases. But, the study of genuine seasonal impact on these diseases is difficult to measure due to many other environment and lifestyle factors which directly affect these diseases. However, several clinical studies have been conducted in different parts of the world, and it has clearly indicated that certain groups of population are highly subjected to seasonal changes, and their maladaptation can possibly lead to several disorders/diseases. Read More
PLoS One 2018 12;13(12):e0207236. Epub 2018 Dec 12.
Department of Biology, University of Turku, Turku, Finland.
Reproduction is predicted to trade-off with long-term maternal survival, but the survival costs often vary between individuals, cohorts and populations, limiting our understanding of this trade-off, which is central to life-history theory. One potential factor generating variation in reproductive costs is variation in developmental conditions, but the role of early-life environment in modifying the reproduction-survival trade-off has rarely been investigated. We quantified the effect of early-life environment on the trade-off between female reproduction and survival in pre-industrial humans by analysing individual-based life-history data for >80 birth cohorts collected from Finnish church records, and between-year variation in local crop yields, annual spring temperature, and infant mortality as proxies of early-life environment. Read More
PLoS One 2018 12;13(12):e0207237. Epub 2018 Dec 12.
Earth and Environmental Sciences, Boston College, Chestnut Hill, Massachusetts, United States of America.
Cranberry growers in New England are increasingly pressured by negative effects associated with global climate change, some of which are familiar to this group (such as precipitation fluctuations and pest pressures), others that are rather new (such as warmer winters that threaten needed chill hours for the plants to bloom). The first study of this population of its kind, we use a survey, supplemented with observations and interviews, to assess Massachusetts cranberry grower attitudes towards climate change, and whether certain conditions of production might be associated with their attitudes. Our findings suggest that certain personal and ecological conditions are associated with greater worry of climate change effects, and that communal conditions of the cranberry grower social network provide some ways to cope with a warming climate. Read More
Spine (Phila Pa 1976) 2018 Dec 11. Epub 2018 Dec 11.
Department of Spine Surgery, Beijing Jishuitan Hospital, Peking University, Beijing, China.
Study Design: Rat nucleus pulposus (NP) cells or annulus fibrosus (AF) cells were stimulated with conditioned media of RAW 264.7 macrophages and vice versa under healthy culture conditions and in the presence of pro-inflammatory mediators. The gene expression of pro-inflammatory mediators, ECM-modifying enzymes, and chemokines, which play important roles in intervertebral disc degeneration (IDD), was determined. Read More
Nurs Res 2018 Dec 12. Epub 2018 Dec 12.
Professor and Associate Vice Dean of Research, University of South Florida College of Nursing, Tampa, FL Founding Director, Center of Community Alliance for Research Education, Professor, Department of Population Sciences, Beckman Research Institute, City of Hope Medical Center, Duarte, CA Associate Professor, The Ohio State University, College of Nursing, Columbus, OH Department of Health Outcomes and Behavior, Division of Population Science, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612 Assistant Professor, College of Nursing, University of Utah, Salt Lake City, UT Professor, Department of Psychological Science, University of North Carolina at Charlotte, Charlotte, NC Senior Member, Division of Population Science, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL Department of Health Disparities Research, MD Anderson Cancer Center, Houston, TX Division of Population Science, H. Lee Moffitt Cancer Center and Research Institute & Department of Oncological Sciences, University of South Florida, College of Medicine, Tampa, FL Assistant Professor, Department of Oncology Sciences, Icahn School of Medicine at Mount Sinai, New York, NY Assistant Professor, Department of Community Health Sciences, Boston University School of Public Health and Department of Social and Behavioral Sciences, and Harvard T.H. Chan School of Public Health, Boston, MA Assistant Professor, Department of Medical Social Sciences and Robert H. Lurie Comprehensive Cancer Center at Northwestern University Feinberg School of Medicine, Chicago, IL Associate Professor, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR Staff Scientist, Project Director, Biobehavioral Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA Strategic Director of Health Disparities Research, Behavioral Research Center, American Cancer Society, Atlanta, GA.
Background: An emphasis on precision health (PH) has stimulated precision medicine studies to focus on the interplay of biological, behavioral, and environmental factors with disease risks, treatments, prognoses, and outcomes affecting health disparities. It is imperative, as well, that improving health equity among underserved populations remains central to the efforts and aims of PH.
Objectives: Apply the transdisciplinary ConNECT Framework: A model for advancing behavioral medicine science and practice to foster health equity to PH by integrating a population health agenda for reducing health disparities. Read More
Nurs Res 2019 Jan/Feb;68(1):3-12
Ashley Schoenfisch, PhD, MSPH, is Assistant Professor, Duke University School of Nursing, and Division of Occupational and Environmental Medicine, Department of Community and Family Medicine, Duke University School of Medicine, Durham, North Carolina. Kristen L. Kucera, PhD, MSPH, ATC, LAT, is Assistant Professor, Department of Exercise and Sport Science, University of North Carolina at Chapel Hill, and Director, National Center for Catastrophic Sport Injury Research, University of North Carolina at Chapel Hill. Hester J. Lipscomb, PhD, is Professor Emeritus, Division of Occupational and Environmental Medicine, Department of Community and Family Medicine, Duke University School of Medicine, Durham, North Carolina. Jennifer McIlvaine, PT, MSPT, CSPHA, is Physical Therapist, Safe Patient Handling Specialist, Duke Occupational and Environmental Safety Office, Durham, North Carolina. Lori Becherer, BS, is Staff Specialist, Duke Occupational and Environmental Safety Office, Durham, North Carolina, and Injury Prevention Research Center, University of North Carolina at Chapel Hill. Tamara James, MA, CPE, CSPHP, is Director, Ergonomics, Duke Occupational and Environmental Safety Office, and Assistant Professor, Division of Occupational and Environmental Medicine, Department of Community and Family Medicine, Duke University School of Medicine, Durham, North Carolina. Susan Avent, MSN, MBA, MHA, RN, NEA-BC, is Associate Chief Nursing Officer, Quality, Duke University Health System, Durham, North Carolina.
Background: Devices to lift, transfer, and reposition patients are recommended for healthcare workers' and patients' safety, but their intended use has yet to be fully realized.
Objective: The aim of this study was to describe hospital nursing staff use of lift/transfer devices and the presence of factors at the time of lifts/transfers with potential to influence whether devices are used.
Methods: Participants were 108 US nursing staff in a university-based medical center and two community hospitals. Read More
J Orthop Trauma 2019 Jan;33 Suppl 1:S33-S37
Orthopaedic Trauma Service, Hospital for Special Surgery, New York, NY.
In physiologically young patients with displaced femoral neck fractures, surgical treatment is aimed at achieving fracture union while preserving native hip anatomy and biomechanics. The intracapsular environment, tenuous vascular supply, and unfavorable hip biomechanics contribute to the high complication rates seen after osteosynthesis of these fractures. Conventional fixation methods for osteosynthesis of femoral neck fractures include multiple cancellous screws, fixed-angle dynamic implants, and fixed-angle length-stable constructs. Read More
J Orthop Trauma 2019 Jan;33 Suppl 1:S20-S26
Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Winston-Salem, NC.
Fixation of young femoral neck fractures represents a challenge in the field of orthopaedic trauma surgery. Conventional methods, including cannulated screw and sliding hip screw constructs, have been studied and found to have similar results with regards to patient outcomes, which has made choosing an optimum fixation strategy difficult. In all of these cases, quality of reduction has been shown to be the most important factor when it comes to creating a favorable environment for fracture healing. Read More
J Orthop Trauma 2019 Jan;33 Suppl 1:S1-S6
Department Orthopaedic Surgery, Wake Forest University School of Medicine, Winston-Salem, NC.
Femoral neck fractures in the physiologically young patient are challenging injuries to manage. A tenuous blood supply and the intrasynovial nature of the fracture create a challenging biological environment. To make matters worse, the biomechanics are equally problematic. Read More
J Occup Environ Med 2018 Dec 11. Epub 2018 Dec 11.
Global Health Institute, Department of Epidemiology and Social Medicine, Faculty of Medicine and Health Sciences, University of Antwerp, Belgium (Mutambudzi); Department of Preventive Medicine & Community Health, University of Texas Medical Branch, Galveston, Texas (Mutambudzi); Stress Research Institute, Stockholm University, Stockholm, Sweden (Theorell); Institute of Occupational, Social, and Environmental Medicine, Centre for Health and Society, Faculty of Medicine, University of Düsseldorf, Germany (Li).
Objective: To examine the prospective associations between baseline job strain and ten-year cumulative incidence of long term sickness absence (LTSA) in the German workforce.
Methods: This study used longitudinal data from the 2001-2010 waves of The German Socio-Economic Panel (SOEP) (n = 9794). Kaplan-Meier survival curves and Cox proportional hazard regression models were used to examine the prospective association between job strain and incidence of LTSA. Read More
J Occup Environ Med 2018 Dec 11. Epub 2018 Dec 11.
Authors of the 2018 American College of Occupational and Environmental Medicine (ACOEM) Guidance Statement on Climate Change University of Colorado, Anschutz Medical Campus, Aurora, CO Authors of the 2018 American College of Occupational and Environmental Medicine (ACOEM) Guidance Statement on Climate Change Authors of the 2018 American College of Occupational and Environmental Medicine (ACOEM) Guidance Statement on Climate Change Authors of the 2018 American College of Occupational and Environmental Medicine (ACOEM) Guidance Statement on Climate Change Authors of the 2018 American College of Occupational and Environmental Medicine (ACOEM) Guidance Statement on Climate Change Authors of the 2018 American College of Occupational and Environmental Medicine (ACOEM) Guidance Statement on Climate Change Authors of the 2018 American College of Occupational and Environmental Medicine (ACOEM) Guidance Statement on Climate Change.
J Occup Environ Med 2018 Dec 11. Epub 2018 Dec 11.
Faculty of Health Medicine and Life Sciences, Maastricht University, Netherlands (Leitaru), Department of Health Promotion, School of Nutrition and Translational Research in Metabolism, Maastricht University, Netherlands (Kremers), Institute of Environmental Medicine, Karolinska Institutet, Sweden (Hagberg, Björklund, Kwak).
Objective: To examine the associations between work-stress and physical activity (PA) with sleep quality while controlling for covariates, including social support.
Methods: A cross-sectional study among employees of a municipality (n = 2765). Data from respondents (n = 1973) with good/poor sleep quality were included. Read More
J Am Assoc Nurse Pract 2018 Dec;30(12):664-666
College of Nursing, University of Florida, Gainesville, Florida.
The American Association of Colleges of Nursing (AACN) last defined academic nursing scholarship in 1999. The AACN recognized faculty scholarship must align with the increasingly complex and dynamic health care environment to prepare nurses for an ever-changing future. The new, broader definition recognizes multiple ways of knowing and values all scholarly contributions, which affect nursing science and the health care system. Read More
Anesth Analg 2018 Dec 11. Epub 2018 Dec 11.
United States National Aeronautics and Space Administration, Ames Research Center, Moffett Field, California.
When life-threatening, critical events occur in the operating room, the fast-paced, high-distraction atmosphere often leaves little time to think or deliberate about management options. Success depends on applying a team approach to quickly implement well-rehearsed, systematic, evidence-based assessment and treatment protocols. Mobile devices offer resources for readily accessible, easily updatable information that can be invaluable during perioperative critical events. Read More