2,155,269 results match your criteria Environmental Toxicology and Pharmacology [Journal]


The Value of Unilateral CIs, CI-CROS and Bilateral CIs, with and without Beamformer Microphones, for Speech Understanding in a Simulation of a Restaurant Environment.

Audiol Neurootol 2018 Dec 11;23(5):270-276. Epub 2018 Dec 11.

Advanced Bionics, Valencia, California, USA.

Objective: Our primary aim was to determine, in a simulation of a crowded restaurant, the value to speech understanding of (i) a unilateral cochlear implant (CI), (ii) a CI plus CROS (contralateral routing of signals) aid system and (iii) bilateral CIs when tested with and without beamforming microphones.

Design: The listeners were 7 CI listeners who had used bilateral CIs for an average of 9 years. The listeners were tested with three device configurations (bilateral CI, unilateral CI + CROS, and unilateral CI), two signal processing conditions (without and with beamformers) and with speech either from +90°, -90°, or from the front. Read More

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December 2018

Sodium Fluoride Arrests Renal G2/M Phase Cell-Cycle Progression by Activating ATM-Chk2-P53/Cdc25C Signaling Pathway in Mice.

Cell Physiol Biochem 2018 11;51(5):2421-2433. Epub 2018 Dec 11.

College of Veterinary Medicine, Sichuan Agricultural University, Ya'an, China.

Background/aims: Excessive fluoride intake can induce cytotoxicity, DNA damage and cell-cycle changes in many tissues and organs, including the kidney. However, the underlying molecular mechanisms of fluoride-induced renal cell-cycle changes are not well understood at present. In this study, we used a mouse model to investigate how sodium fluoride (NaF) induces cell-cycle changes in renal cells. Read More

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December 2018

Circular RNA circPVT1 Promotes Proliferation and Invasion Through Sponging miR-125b and Activating E2F2 Signaling in Non-Small Cell Lung Cancer.

Cell Physiol Biochem 2018 7;51(5):2324-2340. Epub 2018 Dec 7.

Department of Prevention Medicine, School of Public Health, Mudanjiang Medical College, Mudanjiang City,

Background/aims: Circular RNAs (circRNAs) are key regulators in the development and progression of human cancers, however its role in non-small cell lung cancer (NSCLC) tumorigenesis is not well understood. The aim of this study is to identify the expression level of circPVT1 in NSCLC and further investigated its functional relevance with NSCLC progression both in vitro and in vivo.

Methods: Quantative real-time PCR was used for the measurement of circPVT1 in NSCLC specimens and cell lines. Read More

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December 2018

Comparison of Pure-Tone Average Methods for Estimation of Hearing Loss Caused by Environmental Exposure to Lead and Cadmium: Does the Pure-Tone Average Method Which Uses Low-Frequency Ranges Underestimate the Actual Hearing Loss Caused by Environmental Lead and Cadmium Exposure?

Audiol Neurootol 2018 Dec 11;23(5):259-269. Epub 2018 Dec 11.

BK21 PLUS Program in Embodiment: Health-Society Interaction, Department of Public Health Sciences, Graduate School, Korea University, Seoul, Republic of Korea.

Previous studies have reported that exposure to lead and cadmium can damage the inner ear receptor, which perceives high-frequency sounds. However, few studies have used the pure-tone average (PTA), including high-frequency ranges, for the estimation of hearing loss caused by lead and cadmium exposure. We estimated hearing loss using the PTA test, in low-frequency, speech frequency, and high-frequency ranges and compared the differences in the results using 3 PTA calculation methods. Read More

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December 2018

Role and mechanisms of a three-dimensional bioprinted microtissue model in promoting proliferation and invasion of growth-hormone-secreting pituitary adenoma cells.

Biofabrication 2018 Dec 11. Epub 2018 Dec 11.

Department of Mechanical Engineering, Biomanufacturing Center, Tsinghua University, Beijing, CHINA.

Growth-hormone-secreting pituitary adenoma (GHSPA) is a benign tumour with a high incidence and large economic burden, which greatly affects quality of life. The aetiological factors are yet to be clarified for GHSPA. Conventional two-dimensional (2D) monolayer culture of tumour cells cannot ideally reflect the growth status of tumours in the physiological environment, and insufficiencies of in vitro models have severely restricted the progress of cancer research. Read More

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December 2018

Coaxial-cable hierarchical tubular MnO2@Fe3O4@C heterostructures as advanced anode for lithium-ion batteries.

Nanotechnology 2018 Dec 11. Epub 2018 Dec 11.

Institute of Advanced Materials, Nanjing Tech University, Nanjing, CHINA.

Nanostructured manganese oxides have been regarded as promising anodes for lithium-ion batteries (LIBs) due to their high specific capacity, environmental friendliness and low cost. However, as conversion-type electrodes, their scalable utilization is hindered by intrinsically low reaction kinetics, large volume variation and high polarization. Herein, a coaxial-cable tubular heterostructures composed of hollow carbon skeleton, Fe3O4 nanoparticles and ultrathin MnO2 nanosheets from inside out, donated as MnO2@Fe3O4@C, is synthesized via facile two-step hydrothermal process. Read More

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December 2018

Kojic acid applications in cosmetic and pharmaceutical preparations.

Biomed Pharmacother 2018 Dec 8;110:582-593. Epub 2018 Dec 8.

Student Research Committee, Department of Pharmaceutics, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran. Electronic address:

Skin color disorders can be caused by various factors, such as excessive exposure to sunlight, aging and hormonal imbalance during pregnancy, or taking some medications. Kojic acid (KA) is a natural metabolite produced by fungi that has the ability to inhibit tyrosinase activity in synthesis of melanin. The major applications of KA and its derivatives in medicine are based on their biocompatibility, antimicrobial and antiviral, antitumor, antidiabetic, anticancer, anti-speck, anti-parasitic, and pesticidal and insecticidal properties. Read More

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December 2018
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Superior activity of Pd nanoparticles confined in carbon nanotubes for hydrogen production from formic acid decomposition at ambient temperature.

J Colloid Interface Sci 2018 Dec 4;538:474-480. Epub 2018 Dec 4.

College of Chemistry and Environmental Protection Engineering, Southwest Minzu University, Chengdu 610041, Sichuan, China. Electronic address:

Designing highly efficient and low-cost catalysts is essential toward realizing the practical application of hydrogen generation by formic acid decomposition (FAD) under ambient conditions. Herein, we report the synthesis of a hybrid material of Pd nanoparticles encapsulated within carbon nanotubes (CNTs) (Pd-CNTs-in). Transmission electron microscopy images show that most Pd nanoparticles (mean diameter 4. Read More

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December 2018

Graphene from discharged dry cell battery electrodes.

J Hazard Mater 2018 Dec 3;366:358-369. Epub 2018 Dec 3.

Department of Metallurgical and Materials Engineering, Visvesvaraya National Institute of Technology, Nagpur, 440010, India. Electronic address:

Utilization of extracted graphite rods from discharged dry cell batteries for synthesis of graphene oxide / graphene serves two purposes, one is waste management which supports environmental safety and the second is low cost production of graphene oxide / graphene which are highly promising 2D materials in various fields of research. In the present work, a sustainable feasibility for the synthesis of graphene oxide / graphene from graphite rods of waste dry cell batteries is demonstrated. The graphite rods separated from the waste dry cell batteries were subjected to electrochemical exfoliation (ECE) in an acidic media. Read More

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December 2018

Metabolic profiling study on potential toxicity in male mice treated with Dechlorane 602 using UHPLC-ESI-IT-TOF-MS.

Environ Pollut 2018 Nov 27;246:141-147. Epub 2018 Nov 27.

Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, China; University of Chinese Academy of Sciences, Beijing, China. Electronic address:

Dechlorane 602 (Dec 602), a chlorinated flame retardant, has been widely detected in different environmental matrices and biota. However, toxicity data for Dec 602 seldom have been reported. A metabolomics study based on ultra-high performance liquid chromatography coupled with ion trap time-of-flight mass spectrometry was employed to study the urine and sera metabolic profiles of mice administered with Dec 602 (0, 0. Read More

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November 2018

Impact of disinfectant on bacterial antibiotic resistance transfer between biofilm and tap water in a simulated distribution network.

Environ Pollut 2018 Nov 24;246:131-140. Epub 2018 Nov 24.

College of Environmental Science and Engineering, Tongji University, Shanghai, 200092, China.

Bacterial antibiotic resistance (BAR) is profoundly important to human health, but the environmental reservoirs of resistance determinants are poorly understood. BAR of biofilm and tap water were analyzed by using a water distribution simulator where different doses of chlorine and chloramine were used in this study. The results revealed that the disinfectants (≥2 mg/L) suppressed antibiotic resistant bacteria (ARB) in tap water and biofilms, while disinfected water and biofilms had a high relative abundance of ARB. Read More

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November 2018

Prediction of organic contaminant uptake by plants: Modified partition-limited model based on a sequential ultrasonic extraction procedure.

Environ Pollut 2018 Nov 30;246:124-130. Epub 2018 Nov 30.

Department of Environmental Science, Zhejiang University, Hangzhou, Zhejiang 310058, China; Zhejiang Provincial Key Laboratory of Organic Pollution Process and Control, Hangzhou, Zhejiang 310058, China. Electronic address:

Predicting the translocation of organic contaminants to plants is crucial to ensure the quality of agricultural goods and assess the risk of human exposure through the food web. In this study, the performance of a modified plant uptake model was evaluated considering a number of chemicals, such as polycyclic aromatic hydrocarbons (PAHs), organochlorine pesticides (OCPs) and polybrominated diphenyl ethers (PBDEs), with a range of physicochemical properties; different plant species (Ipomoea aquatica Forsk (swamp morning glory), Chrysanthemum coronarium L. (crown daisy), Zea mays L. Read More

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November 2018
2 Reads

Phytotoxicity of individual and binary mixtures of rare earth elements (Y, La, and Ce) in relation to bioavailability.

Environ Pollut 2018 Dec 4;246:114-121. Epub 2018 Dec 4.

School of Environmental Science and Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China; Shanghai Institute of Pollution Control and Ecological Security, Shanghai, 200092, China.

Rare earth elements (REEs) are typically present as mixtures in the environment, but a quantitative understanding of mixture toxicity and interactions of REEs is still lacking. Here, we examined the toxicity to wheat (Triticum aestivum L.) of Y, La, and Ce when applied individually and in combination. Read More

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December 2018
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Daily oxytocin patterns in relation to psychopathy and childhood trauma in residential youth.

Psychoneuroendocrinology 2018 Dec 1;102:105-113. Epub 2018 Dec 1.

Behavioural Science Institute, Radboud University, Nijmegen, the Netherlands; Stichting Conrisq Groep, the Netherlands; Stichting Jeugdzorg Sint Joseph, the Netherlands; Maastricht University, the Netherlands.

Inconsistent findings have been found on the relation between oxytocin levels and psychopathy or callous-unemotional (CU) traits in humans, potentially because the role of trauma in oxytocin secretion and the distinction between primary and secondary psychopathy have been overlooked so far. Primary psychopathy has a stronger biological background, whereas secondary psychopathy mainly develops due to environmental adversity, such as childhood trauma. This study investigated the interaction effects of CU traits and childhood trauma on daily salivary oxytocin levels in 57 males living in residential youth care facilities. Read More

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December 2018

Why we can't determine reliably the age of a subject on the basis of his maturation degree.

J Forensic Leg Med 2018 Dec 5;61:97-101. Epub 2018 Dec 5.

Past Director of the Complex Unit of Auxology, Faculty of Medicine and Surgery, Università degli Studi di Torino, Turin, Italy. Electronic address:

Background: Maturation is the irreversible biological process leading to adult form or function. The degree of maturation can be derived from the examination of maturity indicators, i.e. Read More

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December 2018
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A review of methods used for hazard identification and risk assessment of environmental hazards.

Environ Int 2018 Dec 8;123:231-239. Epub 2018 Dec 8.

Department of Innovation, Evidence and Research, World Health Organization, Av. Appia 20 CH-1211, Geneva 27, Switzerland. Electronic address:

Background: Approximately one quarter of all deaths globally are attributed to living or working in an unhealthy environment, with household and ambient air pollution, along with exposures to ultraviolet radiation and chemicals amongst the leading causes. At present there are no international standards for assessing the risks of these environmental hazards. The use of heterogeneous methods to identify health risks from environmental hazards may reduce the level of confidence the public has in the conclusions that are made. Read More

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December 2018

The association between Parkinson's disease symptom side-of-onset and performance on the MDS-UPDRS scale part IV: Motor complications.

J Neurol Sci 2018 Dec 4;396:262-265. Epub 2018 Dec 4.

Division of General Medicine and Geriatrics, Department of Medicine, Emory School of Medicine, 1648 Pierce Dr. NE, Atlanta, GA 30307, USA; Atlanta VA Center for Visual and Neurocognitive Rehabilitation, 1670 Clairmont Rd., Decatur, GA 30033, USA; Department of Rehabilitation Medicine, Emory School of Medicine, 1648 Pierce Dr. NE, Atlanta, GA 30307, USA. Electronic address:

Introduction: Parkinson's disease (PD) is a neurodegenerative condition associated with aging characterized by loss of dopamine-producing neurons in the substantia nigra pars compacta and a reduction in dopamine levels in the striatum. PD is commonly treated using dopamine-replacement medication called levodopa. Levodopa has decreasing efficacy over time. Read More

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December 2018

Formation mechanisms of Caprolactam-tetraalkyl ammonium halide deep eutectic and its hydrate.

Spectrochim Acta A Mol Biomol Spectrosc 2018 Dec 5;211:189-194. Epub 2018 Dec 5.

School of Environmental Science and Engineering, Hebei University of Science and Technology, Shijiazhuang, Hebei, 050018, China; Pollution prevention biotechnology laboratory of Hebei Province, 050018, China. Electronic address:

Deep eutectic solvents (DES) are generally composed of two or three cheap and safe components that are associated with each other via hydrogen bonds. The formation Caprolactam (CPL)-tetraalkyl ammonium halide (TAAX) DES and its hydrate were investigated using React IR. TAAX was introduced to CPL in the molten state at 353. Read More

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December 2018

Synthesizing, characterizing, and toxicity evaluating of Phycocyanin-ZnO nanorod composites: A back to nature approaches.

Colloids Surf B Biointerfaces 2018 Dec 4;175:221-230. Epub 2018 Dec 4.

Division of Industrial & Environmental Biotechnology, National Institute of Genetic Engineering and Biotechnology (NIGEB), P.O. Box 14155-6343, Tehran, Iran. Electronic address:

C-Phycocyanin pigment was purified from a native cyanobacterial strain using a novel consecutive multi-step procedure and utilized for the first time for the green synthesis of phycocyanin-zinc oxide nanorods (PHY-ZnO NRs) by a simple, low-cost and eco-friendly approach. The PHY-ZnO NRs were characterized using UV-vis spectroscopy, X-ray diffraction (XRD), zeta potential measurement, FTIR, SEM, TEM, differential scanning calorimetry (DSC), thermogravimetric (TGA), and EDX spectroscopy analysis. The UV-vis spectra showed an absorption band at 364 nm which is characteristic of ZnO nanoparticles (ZnONPs). Read More

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December 2018

Exogenous alpha lipoic acid can stimulate photosystem II activity and the gene expressions of carbon fixation and chlorophyll metabolism enzymes in maize seedlings under drought.

J Plant Physiol 2018 Nov 29;232:65-73. Epub 2018 Nov 29.

Department of Biology, Faculty of Science, Karadeniz Technical University, 61080, Trabzon, Turkey. Electronic address:

Protective compounds such as non-enzymatic antioxidants, osmolytes and signal molecules have been applied to plants exposed to various environmental stresses to increase their stress tolerance. However, there are not enough records about the response of plants to alpha lipoic acid (ALA) application with antioxidant properties. Therefore, this study was designed to evaluate the function of exogenous ALA on the photosynthetic performance of maize seedlings grown in hydroponic conditions under drought stress. Read More

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November 2018

A roadmap towards a functional paradigm for learning & memory in plants.

J Plant Physiol 2018 Nov 8;232:209-215. Epub 2018 Nov 8.

Institute of Applied Biosciences, Center for Research & Technology (CERTH), Thessaloniki, Greece.

In plants, the acquisition, processing and storage of empirical information can result in the modification of their behavior according to the nature of the stimulus, and yet this area of research remained relatively understudied until recently. As the body of evidence supporting the inclusion of plants among the higher organisms demonstrating the adaptations to accomplish these tasks keeps increasing, the resistance by traditional botanists and agricultural scientists, who were at first cautious in allowing the application of animal models onto plant physiology and development, subsides. However, the debate retains much of its heat, a good part of it originating from the controversial use of nervous system terms to describe plant processes. Read More

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November 2018

Metabolic and biochemical responses of Potamogeton anguillanus Koidz. (Potamogetonaceae) to low oxygen conditions.

J Plant Physiol 2018 Nov 23;232:171-179. Epub 2018 Nov 23.

Graduate School of Science and Engineering, Saitama University, 255 Shimo-Okubo, Sakura-ku, Saitama 338-8570, Japan; Research Institute of Chuo University, Kasuga, Bunkyo, Tokyo 112-8551, Japan. Electronic address:

Oxygen availability in water is considered one of the most important factors for growth and productivity in aquatic submerged macrophytes. In the present study, the growth, stress responses, and metabolic changes in Potamogeton anguillanus Koidz. (Potamogetonaceae) were assessed after a 21-day exposure to low (hypoxia; dissolved oxygen, DO < 1 mg/L) or null (anoxia) oxygen concentrations in water. Read More

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November 2018

Defense responses of Thuja orientalis to infestation of anholocyclic species aphid Cinara tujafilina.

J Plant Physiol 2018 Nov 22;232:160-170. Epub 2018 Nov 22.

Department of Plant Physiology, Poznań University of Life Sciences, Wołyńska 35, 60-637 Poznań, Poland. Electronic address:

The aim of this study was to determine an interdependence between generation of semiquinone radicals, superoxide anion (O-), manganese ions (Mn) and phenolic content in leaves of Thuja orientalis in response to infestation by varying populations of Cinara tujafilina, i.e. 40 or 80 aphids per plant. Read More

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November 2018

Stable isotope natural abundances (δC and δN) and carbon-water relations as drought stress mechanism response of taro (Colocasia esculenta L. Schott).

J Plant Physiol 2018 Nov 28;232:100-106. Epub 2018 Nov 28.

ISOPlexis Genebank, University of Madeira, Campus da Penteada, 9020-105, Funchal, Madeira, Portugal.

Taro (Colocasia esculenta L. Schott) is an important staple food crop in tropical and developing countries, having high water requirements. The purpose of this study was to evaluate the feasibility of using carbon and nitrogen isotopic composition (δC and δN) as a physiological indicator of taro response to drought, and elucidation of the relationship between the water use efficiency (WUE) under drought conditions and carbon isotope discrimination (ΔC). Read More

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November 2018

Enantioselective LC-MS/MS for anthropogenic markers of septic tank discharge.

Chemosphere 2018 Dec 3;219:191-201. Epub 2018 Dec 3.

School of Pharmacy and Life Sciences, Robert Gordon University, Aberdeen, AB10 7GJ, UK. Electronic address:

Households in rural locations utilize septic tanks for wastewater treatment and can cause surface water contamination. A new methodology was developed to help investigate the role septic tanks play in the dissemination of prescription and over-the-counter drugs, personal care products and stimulants in the aqueous environment. Simultaneous analysis of 16 chiral and achiral anthropogenic markers was achieved using a Chirobiotic V2 enantioselective column in polar ionic mode. Read More

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December 2018

Adsorption and mechanistic study for phosphate removal by magnetic FeO-doped spent FCC catalysts adsorbent.

Chemosphere 2018 Nov 21;219:183-190. Epub 2018 Nov 21.

State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process, East China University of Science and Technology, Shanghai, 200237, China.

The waste materials utilization has attained increasing attention due to the generation of a large number of spent materials. In the current study, a practical magnetic adsorbent (FeO-doped spent Fluid Catalytic Cracking catalysts, abbreviated as FCC@(Fe)-O) was prepared, liable to be separated. The batch experiments were employed to investigate the phosphate removal behavior. Read More

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November 2018

Occurrence and contamination of heavy metals in urban mangroves: A case study in Shenzhen, China.

Chemosphere 2018 Nov 27;219:165-173. Epub 2018 Nov 27.

Guangdong Neilingding Futian National Nature Reserve, Shenzhen, 518000, China.

Urban mangroves are affected by surrounding anthropogenic activities. Heavy metals in urban mangroves lack systematic evaluation, and their relationships with surrounding anthropogenic activities have not been explored with quantified data. In this study, urban mangroves with different urban functional zonings were selected in Shenzhen, South China, including: Shajing mangrove (SJM) and Xixiang mangrove (XXM) featured with industry district, Futian mangrove (FTM) and Baguang mangrove (BGM) featured with central business district and ecological preserve, respectively. Read More

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November 2018

Green synthesis of reduced graphene oxide using bagasse and its application in dye removal: A waste-to-resource supply chain.

Chemosphere 2018 Dec 3;219:148-154. Epub 2018 Dec 3.

School of Environmental Science and Engineering, Fujian Normal University, Fuzhou 350007, Fujian Province, China. Electronic address:

Graphene is usually synthesized through deoxygenation of graphene oxide (GO) by hydrazine which functions as a reducing agent, but the production of graphene via this method suffers a high cost and is often regarded to be not environmental-friendly. In this work, we developed a simple and efficient method for the green reduction of GO to reduced graphene oxide (rGO) dispersed on sugarcane bagasse derived from rGO/bagasse material. The rGO/bagasse was characterized by Scanning electron microscopy, Fourier transform infrared spectroscopy, Raman spectroscopy, Thermogravimetric analysis, X-ray photoelectron spectroscopy and X-ray diffraction analysis. Read More

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December 2018

PVA/CS and PVA/CS/Fe gel beads' synthesis mechanism and their performance in cultivating anaerobic granular sludge.

Chemosphere 2018 Dec 3;219:130-139. Epub 2018 Dec 3.

Department of Environmental Engineering, Xi'an Jiaotong University, Xi'an 710049, China.

Biomass washout from high-speed anaerobic suspended bed bio-reactors is still a challenge to their stable operation. Preserving active biomass to efficiently retain biomass in the reactor is one of the solutions to this problem. Herein, two carriers (polyvinyl alcohol/chitosan (PVA/CS) and PVA/CS/Fe gel beads) were prepared using the cross-linking method. Read More

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December 2018

Phytoextraction of copper from a contaminated soil using arable and vegetable crops.

Chemosphere 2018 Dec 4;219:122-129. Epub 2018 Dec 4.

Department of Agrifood Production and Environmental Sciences, University of Florence, Piazzale Delle Cascine, 18, 50144, Florence, Italy.

Copper (Cu) is among the main contaminant of agricultural soil. The reclamation of Cu polluted soils can be achieved with phytoextraction even if, in general, plants are Cu-excluders and uncommon are Cu-accumulators. The research objectives were to establish the Cu removal capacity by arable and vegetable crops and to investigate the distribution of Cu in their roots, stems and leaves, and fruits. Read More

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December 2018
2 Reads

Enhanced removal of coumarin by a novel O/SPC system: Kinetic and mechanism.

Chemosphere 2018 Dec 4;219:100-108. Epub 2018 Dec 4.

School of Civil Engineering, Southeast University, Nanjing, 210096, China; Key Laboratory of Concrete and Prestressed Concrete Structures of the Ministry of Education, Southeast University, Nanjing, 210096, China.

A high-efficient, eco-friendly and applicable oxidant of percarbonate (SPC, NaCO·1.5HO) is applied as oxidant in ozonation (O) process. In this work, coumarin (COU) decomposition by O and O/SPC was proposed in terms of diverse parameters, including ozone concentration, SPC dosage and pH, with regard to the pseudo-first-order kinetic model. Read More

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December 2018

Estimating soil nitrate leaching of nitrogen fertilizer from global meta-analysis.

Sci Total Environ 2018 Dec 4;657:96-102. Epub 2018 Dec 4.

Key Lab of Plant-Soil Interaction, Ministry of Education, Center for Resources, Environment and Food Security, College Resources and Environmental Sciences, China Agricultural University, Beijing 100193, China. Electronic address:

Global estimates of soil nitrate leaching of applied nitrogen (N) in agricultural production systems are not imprecise; however, the results of some field experiments have suggested that nitrate leaching responds exponentially rather than linearly to increasing N inputs. In this study, we compiled field data on nitrate leaching for 324 site-year combinations extracted from 86 peer-reviewed articles to test the hypothesis that in response to N fertilizer addition, soil nitrate leaching emission factors (EF) do not remain constant, but rather increase rapidly with increasing rates of N application. The averaged overall results showed that the proportional change in the EF response to increasing N input (ΔEF, %) was 0. Read More

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December 2018
1 Read

Linking organochlorine contaminants with demographic parameters in free-ranging common bottlenose dolphins from the northern Adriatic Sea.

Sci Total Environ 2018 Dec 4;657:200-212. Epub 2018 Dec 4.

Morigenos - Slovenian Marine Mammal Society, Kidričevo nabrežje 4, 6330 Piran, Slovenia.

Marine top predators, including marine mammals, are known to bio-accumulate persistent pollutants such as polychlorinated biphenyls (PCBs), a serious conservation concern for these species. Although PCBs declined in European seas since the 1970s-1980s ban, considerable levels still persist in European and Mediterranean waters. In cetaceans, stranded animals are a valuable source of samples for pollutant studies, but may introduce both known and unknown biases. Read More

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December 2018

Impact of upstream oil extraction and environmental public health: A review of the evidence.

Sci Total Environ 2018 Dec 4;657:187-199. Epub 2018 Dec 4.

Department of Preventive Medicine, Keck School of Medicine of University of Southern California, Los Angeles, CA, United States of America.

Upstream oil extraction, which includes exploration and operation to bring crude oil to the surface, frequently occurs near human populations. There are approximately 40,000 oil fields globally and 6 million people that live or work nearby. Oil extraction can impact local soil, water, and air, which in turn can influence community health. Read More

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December 2018
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Elevated arsenic exposure and efficient arsenic metabolism in indigenous women around Lake Poopó, Bolivia.

Sci Total Environ 2018 Dec 2;657:179-186. Epub 2018 Dec 2.

Hydrosciences Montpellier, Institut de Recherche pour le Développement, CNRS, University of Montpellier, France.

Elevated concentrations of inorganic arsenic, one of the most potent environmental toxicants and carcinogens, have been detected in well water around Lake Poopó, Bolivia. This study aimed to assess human exposure to arsenic in villages around Lake Poopó, and also to elucidate whether the metabolism and detoxification of arsenic in this population is as efficient as previously indicated in other Andean areas. We recruited 201 women from 10 villages around Lake Poopó. Read More

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December 2018

Elevated ozone reduced leaf nitrogen allocation to photosynthesis in poplar.

Sci Total Environ 2018 Dec 3;657:169-178. Epub 2018 Dec 3.

State Key Laboratory of Urban and Regional Ecology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Shuangqing Road 18, Haidian District, Beijing 100085, China; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 100049, China; Collaborative Innovation Center of Atmospheric Environment and Equipment Technology, School of Environmental Science and Technology, Nanjing University of Information Science & Technology, Nanjing 210044, China. Electronic address:

We investigated the effects of elevated ozone (O) concentration on leaf nitrogen (N), a key determinant of plant photosynthesis, with two clones of poplar grown in open-top chambers. We focus on the difference between mass-based leaf N concentration (N) and area-based one (N) in their responses to elevated O, and the allocation of N to different leaf components: photosynthetic apparatus, cell walls, and others under elevated O level. Our results showed that elevated O significantly increased N, but reduced N and leaf mass per area (LMA). Read More

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December 2018

Understanding nitrate contamination based on the relationship between changes in groundwater levels and changes in water quality with precipitation fluctuations.

Sci Total Environ 2018 Dec 5;657:146-153. Epub 2018 Dec 5.

Center for Water Cycle, Marine Environment and Disaster Management, Kumamoto University, Japan.

There are growing concerns about nitrate contamination in Kumamoto City, where >700,000 people completely depend on groundwater as a source of drinking water. We found that some groundwater samples showed considerably different nitrate concentrations although their sampling locations were close to one another, and we speculated that this phenomenon was due to the differences in subsurface geological properties. In order to verify this hypothesis, we carried out temporally intensive long-term monitoring of the groundwater levels and water qualities at three of the closely related sampling wells, and the results revealed that the changes in water level and water quality were different at each well. Read More

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December 2018

Mesophyll conductance limitation of photosynthesis in poplar under elevated ozone.

Sci Total Environ 2018 Dec 4;657:136-145. Epub 2018 Dec 4.

Department of Biological and Environmental Sciences, University of Gothenburg, SE-405 30 Gothenburg, Sweden.

Finite mesophyll conductance (g) reduces the rate of CO diffusion from the leaf intercellular space to the chloroplast and constitutes a major limitation of photosynthesis in trees. While it is well established that g is decreased by stressors such as drought and high temperature, few studies have investigated if the phytotoxic air pollutant ozone (O) affects g. We quantified the relative importance of three different types of limitations of photosynthesis in poplar trees exposed to elevated O: decreases in stomatal conductance, g and biochemical photosynthetic capacity. Read More

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December 2018
1 Read

Effectiveness assessment of risk reduction measures at coastal areas using a decision support system: Findings from Emma storm.

Sci Total Environ 2018 Dec 1;657:124-135. Epub 2018 Dec 1.

CIMA/FCT, University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal. Electronic address:

Storms impact coastal areas often causing damages and losses at occupied areas. On a scenario of increasing human occupation at coastal zones and under climate change conditions (including sea level rise and increasing frequency of extreme sea levels), the consequences of storms are expected to be amplified if no adaptation or further management actions are implemented. The selection of the best possible coastal management measures, considering both costs and effectiveness, will be mandatory in the future, in order to optimise resources. Read More

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December 2018

Do concentrations of perfluoroalkylated acids (PFAAs) in isopods reflect concentrations in soil and songbirds? A study using a distance gradient from a fluorochemical plant.

Sci Total Environ 2018 Dec 7;657:111-123. Epub 2018 Dec 7.

Systemic Physiological and Ecotoxicologal Research (SPHERE), Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium. Electronic address:

Perfluoroalkylated acids (PFAAs) are persistent chemicals that have been detected globally in the environment and in wildlife. Although it is known that PFAAs sorb to solid matrices, little is known on PFAA concentrations in soils. PFAA pollution has often been studied in aquatic invertebrates. Read More

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December 2018

Micro(nano)plastics: An un-ignorable carbon source?

Sci Total Environ 2018 Dec 5;657:108-110. Epub 2018 Dec 5.

College of Environmental Science and Engineering, Hunan University, Changsha 410082, PR China; Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha 410082, PR China.

Micro(nano)plastics, new emerging contaminants, are widely found in the environment due to continuous release. Massive and widespread presence of micro(nano)plastics may have a significant impact on the calculation of total organic carbon, and potentially result in misunderstanding of the overall environmental pollution level. Previous studies typically paid attention to the environmental distribution, source, analysis methods and technologies, as well as the environmental and ecological effects of micro(nano)plastics. Read More

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December 2018

Mid-calf skeletal muscle density and its associations with physical activity, bone health and incident 12-month falls in older adults: The Healthy Ageing Initiative.

Bone 2018 Dec 8. Epub 2018 Dec 8.

Department of Community Medicine and Rehabilitation, Geriatric Medicine, Umeå University, Umeå, Sweden.

Background: Lower skeletal muscle density, indicating greater infiltration of adipose tissue into muscles, is associated with higher fracture risk in older adults. We aimed to determine whether mid-calf muscle density is associated with falls risk and bone health in community-dwelling older adults.

Methods: 2214 community-dwelling men and women who participated in the Healthy Ageing Initiative (Sweden) study at age 70 were included in this analysis. Read More

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December 2018
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In vivo transcriptome changes of human white blood cells in response to vitamin D.

J Steroid Biochem Mol Biol 2018 Dec 8. Epub 2018 Dec 8.

School of Medicine, Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland. Electronic address:

In the vitamin D intervention study VitDbol (NCT02063334) blood samples were drawn directly before an oral bolus (2000 µg vitamin D) and 24 h later. The focus of phase II of VitDbol was the transcriptome-wide analysis of the effects of vitamin D gene expression in human peripheral blood mononuclear cells (PBMCs). All five participants responded in an individual fashion to the bolus by increases in serum levels of the vitamin D metabolites 25-hydroxyvitamin D (25(OH)D) and 1α,25-dihydroxyvitamin D (1,25(OH)D). Read More

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December 2018
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What's going on at the entrance? A characterisation of the social interface in ant nests.

Behav Processes 2018 Dec 8. Epub 2018 Dec 8.

Unit of Social Ecology, Université libre de Bruxelles, CP231, Bd du Triomphe, 1050, Brussels, Belgium.

Nest entrances are key locations where information about environmental opportunities and constraints are shared between foragers and inner-nest workers. However, despite its functional value, we still lack a detailed characterisation of the interface between the nest and the environment. Here, we identified the social interface in the ant Myrmica rubra as being the population of ants that faced the nest entrance and that received significantly more contacts from returning foragers than other nearby ants. Read More

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December 2018
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cDNA cloning and expression analysis of glutaredoxin (Grx) 2 in the Pacific white shrimp Litopenaeus vannamei.

Fish Shellfish Immunol 2018 Dec 8. Epub 2018 Dec 8.

Hainan Provincial Key Laboratory for Functional Components Research and Utilization of Marine Bio-resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101, People's Republic of China. Electronic address:

Glutaredoxin (Grx) is a class molecule oxidoreductase, which can regulate the redox state of proteins and plays a key role in antioxidant defense. However, the informations of Grx cDNA sequences and their functions are lack in decapod crustacea. In the present study, the cDNA of LvGrx 2 was cloned from the Pacific white shrimp, Litopenaeus vannamei. Read More

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December 2018

Explaining consumers' intentions towards purchasing green food in Qingdao, China: The amendment and extension of the theory of planned behavior.

Appetite 2018 Dec 8. Epub 2018 Dec 8.

Department of Organic Food Quality and Food Culture, Faculty of Organic Agricultural Sciences, University of Kassel, Nordbahnhofstrasse 1A, 37213, Witzenhausen, Germany.

This study aims to investigate consumers' green food purchase intentions using a survey conducted in Qingdao, Shandong Province, China. Based on the Theory of Planned Behavior (TPB), it models the influences of Chinese culture and consumer characteristics towards purchasing green food products. According to TPB, the behavioral intention is determined by attitude, subjective norms and perceived behavioral control, whereas subjective norms vary according to differences in cultural systems. Read More

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December 2018

Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories.

Cancer Cell 2018 Dec;34(6):996-1011.e8

Finsen Laboratory, Rigshospitalet, DK-2200, Copenhagen, Denmark; Biotech Research & Innovation Centre (BRIC), University of Copenhagen, DK-2200, Copenhagen, Denmark; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, 69120 Heidelberg, Germany; Charité Universitätsmedizin Berlin, Charitéplatz 1, D-10117 Berlin, Germany. Electronic address:

Identifying the earliest somatic changes in prostate cancer can give important insights into tumor evolution and aids in stratifying high- from low-risk disease. We integrated whole genome, transcriptome and methylome analysis of early-onset prostate cancers (diagnosis ≤55 years). Characterization across 292 prostate cancer genomes revealed age-related genomic alterations and a clock-like enzymatic-driven mutational process contributing to the earliest mutations in prostate cancer patients. Read More

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December 2018

Suppressive effect of ascophyllan HS on postprandial blood sugar level through the inhibition of α-glucosidase and stimulation of glucagon-like peptide-1 (GLP-1) secretion.

Int J Biol Macromol 2018 Dec 8. Epub 2018 Dec 8.

Graduate School of Fisheries Science and Environmental Studies, Nagasaki University, Nagasaki 852-8521, Japan. Electronic address:

A sulfated polysaccharide ascophyllan inhibited α-glucosidase in a concentration dependent manner, and >90% activity was inhibited at 1.0 mg/mL. The inhibitory activity was much higher than that of acarbose. Read More

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December 2018

Biopolymers - Calcium phosphates composites with inclusions of magnetic nanoparticles for bone tissue engineering.

Int J Biol Macromol 2018 Dec 8. Epub 2018 Dec 8.

Grigore T. Popa University of Medicine and Pharmacy, Faculty of Medical Bioengineering, Department of Biomedical Sciences, Iasi, Romania. Electronic address:

Composites based on combination of biopolymers (chitosan, hyaluronic acid and bovine serum albumin or gelatin), calcium phosphates (CP) and magnetic nanoparticles have been prepared by a biomimetic co-precipitation method. The biomimetic strategy is inspired by natural mineralization processes, where the synthesized minerals are usually combined with proteins, polysaccharides or other mineral forms to form composite, in physiological conditions of temperature and pH. The morphology of the magnetic composites, studied using scanning electron microscopy (SEM) indicated a macroporous structure, which influenced the retention of simulated biological fluids. Read More

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December 2018
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