14,300 results match your criteria Enterococcal Infections

Mortality predictive factors of People Living with Human-immunodeficiency-virus and Bloodstream Infection.

Int J Infect Dis 2021 Jun 20. Epub 2021 Jun 20.

Internal Medicine department, Coimbra Hospital and University Center, Coimbra, Portugal; Faculty of Medicine, University of Coimbra. Electronic address:

Introduction: Portugal had one of the highest people living with human-immunodeficiency-virus (PLWHIV) mortality rates in Europe, although it is declined after antiretroviral therapy introduction such as bloodstream infections (BSI) mortality in these patients. However BSI mortality is still high and with few European data. So, characterizing BSI and defining prognostic factors may improve our approach. Read More

View Article and Full-Text PDF

Evolution of the Antimicrobial resistance of Bacteria causing Urinary Tract Infections.

Comb Chem High Throughput Screen 2021 Jun 22. Epub 2021 Jun 22.

Basic Science Department, College of Medicine, Hawler Medical University, Erbil, Kurdistan Region. Iraq.

Background: The bacteria, Escherichia coli (E. coli) and Klebsiella pneumoniae (K. pneumoniae), are the main reasons for urinary tract infections (UTIs). Read More

View Article and Full-Text PDF

Bacillus subtilis var. natto increases the resistance of Caenorhabditis elegans to gram-positive bacteria.

J Appl Microbiol 2021 Jun 22. Epub 2021 Jun 22.

Graduate School of Human Life Science, Osaka City University, Osaka, Japan.

Aims: This study aimed to investigate the effect of Bacillus subtilis var. natto on the susceptibility of the model host, Caenorhabditis elegans, to bacterial infection.

Methods And Results: Caenorhabditis elegans worms were fed with a standard food consisting of Escherichia coli OP50 strain (control) or B. Read More

View Article and Full-Text PDF


Wiad Lek 2021 ;74(4):934-939


Objective: The aim: To obtain the first national estimates of the current prevalence rate of SSI after CSEC and antimicrobial resistance of causing pathogens in Ukraine.

Patients And Methods: Materials and methods: We performed a retrospective multhicentre cogort study based surveillance data was conducted from May 2017 to December 2019. The study population consisted of all women who had a cesarean section in 11 regional women hospitals of Ukraine. Read More

View Article and Full-Text PDF


Olena I Krotik

Wiad Lek 2021 ;74(4):896-901


Objective: The aim: To identify the characteristics of the vaginal microbiota, cervical and uterine flora in women with the past history of sexually transmitted infections.

Patients And Methods: Materials and methods: A prospective study and the analysis of the vaginal microbiota, cervical and uterine flora were conducted in 96 women of reproductive age with infertility after the past history of STIs, who planned to get pregnant using ART. Together they made up the group I (main group) and the CG included 30 women of reproductive age, who planned pregnancy without a compromised reproductive history. Read More

View Article and Full-Text PDF

Recommendations of the AFU Infectious Diseases Committee on the prevention, diagnosis and treatment of infections of endo-ureteral equipment.

Prog Urol 2021 Jun 18. Epub 2021 Jun 18.

Service d'Urologie, CHRU Bretonneau, Tours, France.

Introduction: No recent national guidelines exist regarding the management of urinary tract infections (UTIs) in the presence of ureteral stent. This situation could lead to discrepancies in clinical management and less opportunity for a favorable patient's outcome.

Methods: All available data published on Medline® between 1998 and 2018 were systematically searched and reviewed. Read More

View Article and Full-Text PDF

Genetic and behavioral adaptation of Candida parapsilosis to the microbiome of hospitalized infants revealed by in situ genomics, transcriptomics, and proteomics.

Microbiome 2021 06 21;9(1):142. Epub 2021 Jun 21.

Chan Zuckerberg Biohub, San Francisco, CA, USA.

Background: Candida parapsilosis is a common cause of invasive candidiasis, especially in newborn infants, and infections have been increasing over the past two decades. C. parapsilosis has been primarily studied in pure culture, leaving gaps in understanding of its function in a microbiome context. Read More

View Article and Full-Text PDF

Characterization of presumptive vancomycin-resistant enterococci recovered during infection control surveillance in Dallas, Texas, USA.

Access Microbiol 2021 Mar 22;3(3):000214. Epub 2021 Mar 22.

Department of Biological Sciences, The University of Texas at Dallas, Richardson, Texas, USA.

and are Gram-positive bacteria that normally inhabit the human gastrointestinal tract. They are also opportunistic pathogens and can cause nosocomial infection outbreaks. To prevent the spread of nosocomial infections, hospitals may rely on screening methods to identify patients colonized with multidrug-resistant organisms including vancomycin-resistant enterococci (VRE). Read More

View Article and Full-Text PDF

growth-inhibitory effects of L. formulation on intestinal pathogens.

Access Microbiol 2021 Mar 24;3(3):000208. Epub 2021 Feb 24.

Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.

Introduction: Empirical evidence suggests that L. treats enteric infections, including dysentery, cholera, and acute infectious gastroenteritis.

Aim: The aim of this study is to clarify the growth-inhibitory effects of L. Read More

View Article and Full-Text PDF

Industrial dog food is a vehicle of multidrug-resistant enterococci carrying virulence genes often linked to human infections.

Int J Food Microbiol 2021 Jun 6:109284. Epub 2021 Jun 6.

UCIBIO/REQUIMTE, Departamento de Ciências Biológicas, Laboratório de Microbiologia, Faculdade de Farmácia, Universidade do Porto, Porto, Portugal; Departmento de Ciências, Instituto Universitário de Ciências da Saúde (IUCS), Cooperativa de Ensino Superior Politécnico e Universitário (CESPU), CRL, Gandra, Portugal; ESCMID Food- and Water-borne Infections Study Group (EFWISG). Electronic address:

The increase in the number of pets in recent years has been followed by an exponential growth of the industrial pet food sector, which has been accompanied by new food safety risks, namely antibiotic resistance. The aim of this study was to investigate whether dog food commercially available in Portugal is a reservoir of clinically-relevant antibiotic resistant Enterococcus. Fifty-five samples (25 brands; 22 wet, 14 raw frozen, 8 dry, 7 treats and 4 semi-wet) were collected on 9 commercial surfaces in the Porto region (September 2019 to January 2020). Read More

View Article and Full-Text PDF

Bloodstream infections among intestinal and multivisceral transplant recipients.

Transpl Infect Dis 2021 Jun 18:e13668. Epub 2021 Jun 18.

Medstar Georgetown Transplant Institute.

Objective: To examine the etiologies, risk factors, and microbiology of bloodstream infections (BSIs) among intestinal and multivisceral transplant recipients in the two year post-operative period.

Methods: A retrospective medical record review of adults intestinal or multivisceral transplant recipients between 2003 to 2015. Descriptive statistics were used to describe cohort data. Read More

View Article and Full-Text PDF

Enterococcus faecalis in blood cultures-a prospective study on the role of persistent bacteremia.

Diagn Microbiol Infect Dis 2021 May 18;101(1):115433. Epub 2021 May 18.

Section for Infection Medicine, Department of Sciences Lund, Lund University, Lund, Sweden; Skåne University Hospital, Lund, Sweden. Electronic address:

Enterococcus faecalis can cause infective endocarditis and other complicated infections. We prospectively investigate the incidence of persistent bacteremia with E. faecalis. Read More

View Article and Full-Text PDF

Azoles containing naphthalene with activity against Gram-positive bacteria: studies and predictions for flavohemoglobin inhibition.

J Biomol Struct Dyn 2021 Jun 17:1-10. Epub 2021 Jun 17.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.

Azoles are first-line drugs used in fungal infections. Topical antifungals, such as miconazole and econazole, are known to be active against Gram-positive bacteria, which was reported to result from bacterial flavohemoglobin (flavoHb) inhibition. Dual antibacterial/antifungal action is believed to have benefits for antimicrobial chemotherapy. Read More

View Article and Full-Text PDF

Epidemiological and Clinical Characterization of Superinfections in Critically Ill Coronavirus Disease 2019 Patients.

Crit Care Explor 2021 Jun 11;3(6):e0430. Epub 2021 Jun 11.

Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.

To describe the epidemiology of superinfections (occurring > 48 hr after hospital admission) and their impact on the ICU and 28-day mortality in patients with coronavirus disease 2019 with acute respiratory distress syndrome, requiring mechanical ventilation.

Design: Retrospective analysis of prospectively collected observational data.

Setting: University-affiliated adult ICU. Read More

View Article and Full-Text PDF

Biofilm Formation by Pathogens Causing Ventilator-Associated Pneumonia at Intensive Care Units in a Tertiary Care Hospital: An Armor for Refuge.

Biomed Res Int 2021 28;2021:8817700. Epub 2021 May 28.

Department of Clinical Microbiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.

Background: Emerging threat of drug resistance among pathogens causing ventilator-associated pneumonia (VAP) has resulted in higher hospital costs, longer hospital stays, and increased hospital mortality. Biofilms in the endotracheal tube of ventilated patients act as protective shield from host immunity. They induce chronic and recurrent infections that defy common antibiotics. Read More

View Article and Full-Text PDF

Low Proportion of Linezolid and Daptomycin Resistance Among Bloodborne Vancomycin-Resistant and Methicillin-Resistant Infections in Europe.

Front Microbiol 2021 31;12:664199. Epub 2021 May 31.

Unit 37: Nosocomial Infections, Surveillance of Antimicrobial Resistance and Consumption, Robert Koch Institute, Berlin, Germany.

Vancomycin-resistant (VREF) and methicillin-resistant (MRSA) are associated with significant health burden. We investigated linezolid and daptomycin resistance among VREF and MRSA in the EU/EEA between 2014 and 2018. Descriptive statistics and multivariable logistic regression were used to analyze 6,949 VREF and 35,131 MRSA blood isolates from patients with bloodstream infection. Read More

View Article and Full-Text PDF

Comparative Biofilm Assays Using Enterococcus faecalis OG1RF Identify New Determinants of Biofilm Formation.

mBio 2021 Jun 15:e0101121. Epub 2021 Jun 15.

Department of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, Minnesota, USA.

Enterococcus faecalis is a common commensal organism and a prolific nosocomial pathogen that causes biofilm-associated infections. Numerous E. faecalis OG1RF genes required for biofilm formation have been identified, but few studies have compared genetic determinants of biofilm formation and biofilm morphology across multiple conditions. Read More

View Article and Full-Text PDF

Antimicrobial susceptibility of gram-positive and gram-negative bacteria: a 5-year retrospective analysis at a multi-hospital healthcare system in Saudi Arabia.

Ann Clin Microbiol Antimicrob 2021 Jun 12;20(1):43. Epub 2021 Jun 12.

College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.

Background: Studying time-related changes in susceptible pathogens causing healthcare-associated infections (HAIs) is vital in improving local antimicrobial and infection control practices.

Objectives: Describe susceptibility patterns to several antimicrobials in gram-positive and gram-negative pathogens isolated from patients causing HAIs at three private tertiary care hospitals in Saudi Arabia over a 5-year period.

Methods: Data on trends of antimicrobial susceptibility among bacteria causing HAIs events in children and adults at three tertiary private hospitals located in Riyadh and Qassim, Saudi Arabia, were collected retrospectively between 2015 and 2019 using the surveillance data datasets. Read More

View Article and Full-Text PDF

Etiology and prevalence of ESBLs in adult community-onset urinary tract infections in East China: a prospective multicenter study.

J Infect 2021 Jun 8. Epub 2021 Jun 8.

Department of Infectious Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Key Laboratory of Microbial Technology and Bioinformatics of Zhejiang Province, Hangzhou, Zhejiang, China; Regional Medical Center for National Institute of Respiratory Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China. Electronic address:

Objectives: Community onset urinary tract infections (COUTIs) drew attention recently owing to their increased prevalence and associations with resistant pathogens. The study is aimed at investigating the etiology of COUTIs as well as prevalence and the related risk factors of extended-spectrum β-lactamase (ESBL) in COUTIs in China.

Methods: The prospective study was performed in nineteen hospitals during November 1, 2017 and August 31, 2019. Read More

View Article and Full-Text PDF

Comparative analysis of bacterial content, levels of lipopolysaccharides and lipoteichoic acid in symptomatic and asymptomatic endodontic infections at different stages of endodontic treatment.

Clin Oral Investig 2021 Jun 11. Epub 2021 Jun 11.

Department of Restorative Dentistry, Division of Endodontics, Piracicaba Dental School - State University of Campinas, UNICAMP, Av Limeira 901, Piracicaba, São Paulo, Brazil.

Objectives: This study aimed to detect the presence of specific bacteria and to evaluate the levels of lipopolysaccharides (LPS) and lipoteichoic acid (LTA) in symptomatic necrotic root canals associated with acute apical abscess (symptomatic group - GI). It also aimed to compare the findings with those presented by asymptomatic necrotic root canals (asymptomatic group - GII) in the different stages of the endodontic treatment.

Materials And Methods: Microbiological samples were collected from 20 root canals, including purulent collection from acute apical abscesses, before and after chemo-mechanical preparation (CMP) preparation (CMP) with chlorhexidine gel 2% and after 30 days of intracanal medication (ICM) with (Ca[OH]) + chlorhexidine. Read More

View Article and Full-Text PDF

The interface between COVID-19 and bacterial healthcare-associated infections.

Ronan F O'Toole

Clin Microbiol Infect 2021 Jun 7. Epub 2021 Jun 7.

Department of Pharmacy and Biomedical Sciences, School of Molecular Sciences, College of Science, Health and Engineering, La Trobe University, Victoria, Australia. Electronic address:

Background: A wide range of bacterial infections occur in COVID-19 patients, particularly, in those with severe coronaviral disease. Some of these are community acquired co-infections.

Objective: To review recent data which indicate the occurrence of hospital-onset bacterial infections, including with antibiotic-resistant isolates, in COVID-19 patients. Read More

View Article and Full-Text PDF

Infection related mortality in adults and children undergoing allogeneic hematopoietic cell transplantation: An Australian registry report.

Transplant Cell Ther 2021 Jun 7. Epub 2021 Jun 7.

National Centre for Infection in Cancer, Peter MacCallum Cancer Centre, Melbourne, Australia; Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Australia.

Background: Infection related mortality (IRM) is the most common non-relapse mortality reported post allogeneic hematopoietic cell transplantation (HCT). Information on the incidence and timing of specific infective organisms and the risk factors for IRM is essential to developing prevention strategies.

Objective: This report provides the first account of IRM in adults and children undergoing HCT in Australia. Read More

View Article and Full-Text PDF

Broad-Spectrum Photo-Antimicrobial Polymers Based on Cationic Polystyrene and Rose Bengal.

Front Med (Lausanne) 2021 24;8:641646. Epub 2021 May 24.

Departamento de Química Inorgánica y Orgánica, Universitat Jaume I, Castellón, Spain.

New strategies to fight bacteria and fungi are necessary in view of the problem of iatrogenic and nosocomial infections combined with the growing threat of increased antimicrobial resistance. Recently, our group has prepared and described two new readily available materials based on the combination of Rose Bengal (singlet oxygen photosensitizer) and commercially available cationic polystyrene (macroporous resin Amberlite® IRA 900 or gel-type resin IRA 400). These materials showed high efficacy in the antimicrobial photodynamic inactivation (aPDI) of . Read More

View Article and Full-Text PDF

Causative Agents of Urinary Tract Infections in Elderly Men with Benign Prostatic Hyperplasia: a Microbiological Evaluation.

Clin Lab 2021 Jun;67(6)

Background: Benign prostatic hyperplasia is an important risk factor for urinary tract infections. In this study, the causative agents of urinary tract infections were isolated from urine samples of benign prostatic hyperplasia patients aged 65 and older. Bacteremia risk and the patterns of antibiotic resistance were investigated to guide clinicians in empirical antibiotic treatment. Read More

View Article and Full-Text PDF

Raoultella ornithinolytica urinary tract infection in a pediatric patient with T-cell precursor acute lymphoblastic leukemia.

Bol Med Hosp Infant Mex 2021 Jun 9. Epub 2021 Jun 9.

Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA; Comité de Medicina Tropical, Zoonosis y Medicina del Viajero, Asociación Colombiana de Infectología, Bogotá, Colombia.

Background: Currently, Raoultella ornithinolytica is considered an emerging pathogen of community- and hospital-acquired infection, particularly in patients with immunodeficiencies, malignancies, anatomical abnormalities, or after invasive procedures. Pediatric infections with R. ornithinolytica are exceedingly rare, with only six previously reported cases, of which only two were reported as a urinary tract infection. Read More

View Article and Full-Text PDF

Influence of Luseogliflozin on Vaginal Bacterial and Fungal Populations in Japanese Patients With Type 2 Diabetes.

J Clin Med Res 2021 May 25;13(5):309-316. Epub 2021 May 25.

Office of Medical Education, School of Medicine, International University of Health and Welfare, 4-3, Kozunomori, Narita-shi, Chiba 286-8686, Japan.

Background: Selective sodium-glucose cotransporter 2 inhibitors, known to lower the blood glucose levels by promoting the urinary glucose excretion, can predispose to genitourinary infections. This prospective study investigated the influence of selective sodium-glucose cotransporter 2 inhibitors luseogliflozin on the vaginal flora of the pre- and postmenopausal women with type 2 diabetes mellitus.

Methods: Twelve premenopausal and 24 postmenopausal female Japanese patients with type 2 diabetes mellitus took luseogliflozin 2. Read More

View Article and Full-Text PDF

Bacterial and fungal bloodstream infections in pediatric liver and kidney transplant recipients.

BMC Infect Dis 2021 Jun 8;21(1):541. Epub 2021 Jun 8.

Viro-immunology Research Unit, Department of Infectious Diseases 8632, Rigshospitalet, University of Copenhagen, Blegdamsvej 9B, DK-2100, Copenhagen Ø, Denmark.

Background: Bacterial and fungal bloodstream infections (BSI) are common after pediatric liver and kidney transplantations and associated with morbidity and mortality. However, knowledge about incidence rates, pathogen composition, and resistance patterns is limited. We aimed to describe the pattern of bacterial and fungal BSI in a cohort of pediatric liver and kidney transplant recipients. Read More

View Article and Full-Text PDF

Readily Adapts Membrane Phospholipid Composition to Environmental and Genetic Perturbation.

Front Microbiol 2021 21;12:616045. Epub 2021 May 21.

Department of Microbiology, University of Tennessee, Knoxville, Knoxville, TN, United States.

The bacterial lipid membrane, consisting both of fatty acid (acyl) tails and polar head groups, responds to changing conditions through alteration of either the acyl tails and/or head groups. This plasticity is critical for cell survival as it allows maintenance of both the protective nature of the membrane as well as functioning membrane protein complexes. Bacteria that live in fatty-acid rich environments, such as those found in the human host, can exploit host fatty acids to synthesize their own membranes, in turn, altering their physiology. Read More

View Article and Full-Text PDF

Pediatric sepsis cases diagnosed with group B streptococcal meningitis using next-generation sequencing: a report of two cases.

BMC Infect Dis 2021 Jun 5;21(1):531. Epub 2021 Jun 5.

Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Background: Group B Streptococcus (GBS) is an important cause of invasive infection in neonates and infants. Cerebrospinal fluid (CSF) findings and culture may not show evidence of infection early in GBS meningitis. Next-generation sequencing (NGS) has the potential to detect microbial genetic material in patients with infectious diseases. Read More

View Article and Full-Text PDF

Antibiofilm activity of laser ablation with indocyanine green activated photodynamic therapy on root canals infected with Enterococcus faecalis.

Photodiagnosis Photodyn Ther 2021 Jun 1:102377. Epub 2021 Jun 1.

Department of Preventive and Restorative Dentistry, São Paulo State University (UNESP) School of Dentistry, Araçatuba, SP, Brazil. Electronic address:

Background: Antimicrobial Photodynamic therapy (aPDT) is used as an adjunct to endodontic treatment to enhance the microbial reduction in the root canal system. However, studies evaluating the impact of Laser Ablation with Indocyanine Green (ICG) are scarce. Thus, this in vitro study aimed to evaluate the efficiency of Laser Ablation with ICG using different laser parameters compared with aPDT using photosensitizer methylene blue (MB) and curcumin (CUR) on the reduction of E. Read More

View Article and Full-Text PDF