3,930 results match your criteria Endophthalmitis Fungal


Utility of Ophthalmologic Screening for Patients With Candida Bloodstream Infections: A Systematic Review.

JAMA Ophthalmol 2019 Apr 18. Epub 2019 Apr 18.

Vanderbilt University School of Medicine, Nashville, Tennessee.

Importance: The Infectious Diseases Society of America recommends ophthalmologic examinations for everyone with positive Candida blood culture results (candidemia) to screen for endophthalmitis, a practice that remains controversial because of multiple concerns for its limited usefulness and potential for harm.

Objective: To determine guideline efficacy by reconciling discrepancies in the incidence of endophthalmitis and evaluating outcomes of studies assessing ophthalmologic screening for candidemia.

Evidence Review: PubMed literature searches, including the search terms candidemia, fungemia, chorioretinitis, and endophthalmitis, identified longitudinal studies prior to 2018 of patients who underwent ophthalmologic evaluations in the setting of positive fungal blood culture results regardless of symptoms or clinical status. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamaophthalmol.2019.0733DOI Listing

Recurrent Endophthalmitis.

Korean J Ophthalmol 2019 Apr;33(2):200-201

Department of Ophthalmology, Kosin University College of Medicine, Busan, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3341/kjo.2018.0071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462466PMC

Injectable Schiff base polysaccharide hydrogels for intraocular drug loading and release.

J Biomed Mater Res A 2019 Apr 4. Epub 2019 Apr 4.

Material Science and Engineering College, Qingdao University, Qingdao, Shandong, 266071, People's Republic of China.

A novel voriconazole (VCZ)-loaded injectable hydrogel was in situ synthetized via a Schiff base reaction between polyaldehyde dextran (PAD) and carboxymethyl chitosan (CMCTS) for intraocular drug loading and release. Water-insoluble VCZ, which is an effective agent in clinic treating fungal endophthalmitis, was loaded through the inclusion into the β-cyclodextrin (β-CD) cavity based on host-guest interaction on the linear poly β-CD chain, which was in situ twined in the cross-linked hydrogel structure. The gelation time, degradation, and drug release process were investigated by studying three kinds of hydrogels with different volume ratio of PAD to CMCTS resolving in phosphate buffered saline (PBS) solution (3:7, 6:7, 9:7), respectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jbm.a.36677DOI Listing
April 2019
1 Read

A Case of Pulmonary Mycetoma Caused by .

Eur J Case Rep Intern Med 2019 20;6(2):001040. Epub 2019 Feb 20.

Internal Medicine Department, Hospital de Egas Moniz, Lisbon, Portugal.

Fungal infections caused by species are rare. Although most cases of human infection occur in immunocompromised patients, this species is also being increasingly recognized as a pathogen in immunocompetent individuals. and are the most common pathogens in humans. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12890/2019_001040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432827PMC
February 2019
5 Reads

A diagnostic dilemma in a patient with delayed onset endophthalmitis.

Saudi J Ophthalmol 2019 Jan-Mar;33(1):99-101. Epub 2018 Jul 9.

Department of Ophthalmology, Baskent University, Faculty of Medicine, Ankara, Turkey.

We report a case of nonpainful uveitis nine months after an uncomplicated phacoemulsification cataract surgery. Chronic postoperative endophthalmitis was suspected. Diagnostic vitrectomy and partial capsular bag removal was performed, but the specimens cultured in microbiology laboratory showed no pathogens. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.sjopt.2018.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424715PMC
July 2018
1 Read

Characteristics and Outcomes of Endogenous Endophthalmitis: Eight-Year Experience at a Tertiary Care Center.

Ophthalmol Retina 2019 Jan 6;3(1):61-72. Epub 2018 Sep 6.

Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts. Electronic address:

Purpose: To describe the characteristics and outcomes of endogenous endophthalmitis.

Design: Retrospective case series.

Participants: Patients with endogenous endophthalmitis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.oret.2018.08.009DOI Listing
January 2019
2 Reads

ENDOGENOUS ENDOPHTHALMITIS IN WESTERN AUSTRALIA: A Sixteen-Year Retrospective Study.

Retina 2019 Mar 12. Epub 2019 Mar 12.

Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth, Western Australia, Australia.

Purpose: To review the clinical features, microbiology spectrum, management, and outcomes of patients with endogenous endophthalmitis in Western Australia over a 16-year period.

Methods: This is a retrospective chart review of all patients with endogenous endophthalmitis who presented to all tertiary ophthalmology departments between 2000 and 2015 in Western Australia.

Results: Sixty-six eyes of 57 patients with endogenous endophthalmitis were identified, and follow-up data were available for a mean of 554 days. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/IAE.0000000000002512DOI Listing
March 2019
11 Reads

Post-traumatic endophthalmitis caused by .

JMM Case Rep 2019 Feb 20;6(2):e005175. Epub 2019 Feb 20.

Departament of Microbiology, University Hospital Marqués de Valdecilla - IDIVAL, Santander, Spain.

Introduction: complex has been associated with infections in both immunocompetent and immunocompromised patients. Infection can be localized or disseminated, affecting skin and soft tissues, the respiratory system, bones and joints, the circulatory system and especially the central nervous system. Ocular infections such as keratitis, scleritis, conjunctivitis, dacryocystitis, orbital cellulitis and endophthalmitis due to spp. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1099/jmmcr.0.005175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421342PMC
February 2019
3 Reads

Endophthalmitis following Suture Removal - Clinical Outcomes and Microbiological Profile.

Semin Ophthalmol 2019 16;34(2):115-123. Epub 2019 Mar 16.

b Smt Kanuri Santhamma Center for Vitreo- Retina diseases , Hyderabad , India.

Aims: To review the clinical profile and report the microbiology and treatment outcomes of endophthalmitis following suture removal.

Methods: In this multi-center, retrospective interventional case series, 11 eyes of 11 patients who developed endophthalmitis following suture removal from January 2006 to December 2017 were reviewed.

Results: Nine of the 11 patients developed a culture-proven, acute onset endophthalmitis [5. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/08820538.2019.1590605DOI Listing
April 2019
1 Read
1.196 Impact Factor

Bartonella henselae- and quintana-associated uveitis: a case series and approach of a potentially severe disease with a broad spectrum of ocular manifestations.

Int Ophthalmol 2019 Mar 9. Epub 2019 Mar 9.

Department of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Stavros Niarchos Avenue, 45110, Ioannina, Greece.

Purpose: To evaluate the clinical manifestations of intraocular inflammation associated with Bartonella infection and describe the assessment and management of patients with cat-scratch disease (CSD).

Methods: This is a retrospective review of the clinical records of patients diagnosed with Bartonella henselae and Bartonella quintana intraocular inflammation from 2011 to 2018 in the Department of Ocular Inflammations and Infections of the University Eye Clinic of Ioannina (Greece). An analysis of the current literature concerning Bartonella-related intraocular infections was also carried out. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10792-019-01096-7
Publisher Site
http://dx.doi.org/10.1007/s10792-019-01096-7DOI Listing
March 2019
18 Reads

Endophthalmitis associated with fungal keratitis and penetrating injuries in North China.

Eur J Ophthalmol 2019 Mar 4:1120672119833896. Epub 2019 Mar 4.

3 Clinical Lab of Qilu Hospital (Qingdao), Shandong University, Qingdao, P.R.China.

Purpose:: To report the laboratory findings, management strategies, and visual outcomes of culture-proven exogenous fungal endophthalmitis in North China.

Methods:: The microbiological and treatment records of patients with culture-positive exogenous fungal endophthalmitis who visited the Affiliated Hospital of Qingdao University from January 2012 to December 2016 were reviewed.

Results:: A total of 39 eyes (39 patients) were identified over a 5-year period. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1120672119833896DOI Listing
March 2019
3 Reads

Successful treatment of Fusarium solani anterior chamber involvement secondary to contact lens associated corneal ulcer with intracameral Amphotericin B.

GMS Ophthalmol Cases 2019 12;9:Doc03. Epub 2019 Feb 12.

Department of Ophthalmology, University Hospital Regensburg, Germany.

spp. are leading fungal pathogenes in contact lens associated keratitis and may evoke endophthalmitis. Since spp. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3205/oc000092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381420PMC
February 2019
1 Read

Clinical outcomes in ocular pythiosis patients treated with a combination therapy protocol in Thailand: A prospective study.

Med Mycol 2019 Feb 26. Epub 2019 Feb 26.

Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Ocular pythiosis is the second most common form of human pythiosis, and the rates of evisceration/enucleation in Thailand are 55-79%. This prospective study was conducted to evaluate treatment outcomes of the combination therapy protocol and the potential use of serum (1→3)-β-glucan (BG) and Pythium insidiosum-specific antibody (Pi-Ab) as an aid to diagnosis and monitoring of ocular pythiosis. Thirty patients were enrolled in the study and 14 (non-globe salvage) required evisceration/enucleation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/mmy/myz013DOI Listing
February 2019
2 Reads

Iris melanin pigment as a masquerade of Gram-positive cocci after penetrating ocular trauma.

Digit J Ophthalmol 2018 18;24(4):27-30. Epub 2018 Oct 18.

Department of Ophthalmology, University of North Carolina, Chapel Hill, North Carolina.

We describe a case of penetrating eye injury that resulted in a post-injury day 1 hypopyon, leading to concern for endophthalmitis and phacoanaphylaxis. A Gram stain prepared by the clinical microbiology laboratory was interpreted as Gram-positive cocci (GPC). However, when cultures returned negative, further investigation with microbiology and pathology found that what was thought to be GPC was actually iris melanin pigment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5693/djo.02.2018.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380259PMC
March 2019
1 Read

Culture-Proven Candida Albicans Endogenous Endophthalmitis in a Patient with Onychomycosis.

Ocul Immunol Inflamm 2019 Feb 22:1-4. Epub 2019 Feb 22.

a Department of Ophthalmology , Ankara University Faculty of Medicine , Ankara , Turkey.

Purpose: To report a case of Candida albicans endogenous endophthalmitis in an immunocompetent patient with onychomycosis.

Methods: Retrospective case report.

Results: A 40-year-old man with onychomycosis presented with C. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/09273948.2019.1568503DOI Listing
February 2019

Trends in microbiological spectrum of endophthalmitis at a single tertiary care ophthalmic hospital in India: a review of 25 years.

Eye (Lond) 2019 Feb 21. Epub 2019 Feb 21.

Smt. Kanuri Santhamma Centre for Vitreo-Retinal Diseases, L. V. Prasad Eye Institute, Hyderabad, India.

Purpose: To determine trends in the microbial spectrum of endophthalmitis over the past 25 years and to review its antibiotic susceptibility patterns over the last 10 years.

Methods: Microbiology records of culture-positive endophthalmitis cases from 1991 to 2015 were reviewed. Additionally, data between 2005 and 2015 was also analyzed for trends in antibiotic susceptibility. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41433-019-0380-8DOI Listing
February 2019
2 Reads
1.897 Impact Factor

endophthalmitis following dexamethasone intravitreal implant.

Indian J Ophthalmol 2019 Mar;67(3):424-426

Department of Ophthalmology, James Cook University Hospital, Middlesbrough, United Kingdom; Department of Ophthalmology, Zagazig University, Egypt.

We present a unique case of endophthalmitis with Staphylococcus lugdunensis following dexamethasone intravitreal implant for branch retinal vein occlusion associated with cystoid macular edema. Patient did not show favorable clinical response after vitrectomy and intravitreal antibiotics; so, we decided to repeat vitrectomy, remove the steroid implant and fill the eye with silicon oil, and repeat intravitreal vancomycin. Vision has improved from hand movements at presentation to counting fingers at 1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/ijo.IJO_720_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407396PMC
March 2019
0.927 Impact Factor

Impact of antibiotic resistance of pathogens and early vitrectomy on the prognosis of infectious endophthalmitis: a 10-year retrospective study.

Graefes Arch Clin Exp Ophthalmol 2019 Apr 13;257(4):805-813. Epub 2019 Feb 13.

Department of Ophthalmology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211, Eonjuro, Gangnam-gu, Seoul, 135-720, South Korea.

Purpose: Infectious endophthalmitis (IE) is a severe complication that can lead to blindness even with treatment. However, the impact of antibiotic resistance and early vitrectomy on its prognosis has scarcely been documented. This study investigated the impact of antibiotic resistance of pathogen and early vitrectomy on the prognosis of IE. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00417-019-04261-xDOI Listing
April 2019
1 Read
1.908 Impact Factor

endophthalmitis in a Cuban pediatric patient.

SAGE Open Med Case Rep 2019 30;7:2050313X19827403. Epub 2019 Jan 30.

Pedro Kourí Tropical Medicine Institute, La Habana, Cuba.

Bacterial endophthalmitis is the most severe form of vision-threatening ocular infection. is a primary respiratory pathogen that has been associated with several extrapulmonary manifestation, including ocular infection. In this work, we presented the microbiology diagnosis of an endophalmitis by using a novel A. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/2050313X19827403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354299PMC
January 2019
1 Read

New insights into culture negative endophthalmitis by unbiased next generation sequencing.

Sci Rep 2019 Jan 29;9(1):844. Epub 2019 Jan 29.

Jhaveri Microbiology Centre, Brien Holden Eye Research Centre, L. V. Prasad Eye Institute, Hyderabad, Telangana, India.

The proof-of-concept, study to investigate the presence of microorganisms in presumed infectious endophthalmitis using Next generation sequencing (NGS) was carried out in vitreous biopsies from 34 patients with endophthalmitis, and thirty patients undergoing surgery for non-infectious retinal disorders as controls. Following DNA extraction using the Qiagen mini kit and PCR amplification of the V3-V4 regions of the bacterial 16S rRNA and ITS 2 region of fungus, they samples were sequenced on an Illumina HiSeq 2500 Machine. Paired reads were curated, taxonomically labeled, and filtered. Read More

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41598-018-37502-w
Publisher Site
http://dx.doi.org/10.1038/s41598-018-37502-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351655PMC
January 2019
12 Reads

ENTEROCOCCUS ENDOPHTHALMITIS: Clinical Settings, Antimicrobial Susceptibility, and Management Outcomes.

Retina 2019 Jan 23. Epub 2019 Jan 23.

Srimati Kanuri Santhamma Centre for Vitreo-Retinal Diseases, L V Prasad Eye Institute, Hyderabad, Telangana, India.

Purpose: To report the clinical presentation and management outcome of patients with endophthalmitis caused by Enterococcus species and to report the susceptibility profile of the isolates.

Methods: Twenty-nine cases with culture-proven Enterococcus endophthalmitis from January 2005 to May 2018 underwent vitrectomy/vitreous biopsy, intravitreal antibiotic with or without additional procedures. The undiluted vitreous was subjected to microbiologic evaluation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/IAE.0000000000002462DOI Listing
January 2019
3.243 Impact Factor

Post-Traumatic Endophthalmitis due to Acinetobacter radioresistens: Virulence Potential of Commensal Bacteria.

Infect Disord Drug Targets 2019 Jan 23. Epub 2019 Jan 23.

Department of Microbiology, Government Medical College and Hospital, Sector 32, Chandigarh. India.

Acinetobacter species are widely distributed in soil, water and hospital environment. In addition to A. calcoaceticus-baumannii complex, the clinically most relevant species, there are other genomospecies which are less frequently identified, mostly due to lack of accurate methods for routine identification. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1871526519666190123145321DOI Listing
January 2019
8 Reads

Early Pars Plana Vitrectomy for Treatment of Acute Infective Endophthalmitis.

Asia Pac J Ophthalmol (Phila) 2019 Jan-Feb;8(1):3-7. Epub 2019 Jan 22.

Retina Unit, Sydney Eye Hospital, Sydney, NSW, Australia.

Purpose: To evaluate the efficacy and safety of early pars plana vitrectomy (PPV) for the treatment of acute infective endophthalmitis, and identify prognostic factors for better visual outcome.

Design: Retrospective cohort study.

Methods: Consecutive patients who underwent early PPV within 72 hours of presentation for the treatment of acute infective bacterial endophthalmitis and presented to a large tertiary referral center in New South Wales, Australia, between January 2009 and December 2013 were included. Read More

View Article

Download full-text PDF

Source
http://www.apjo.org/Apjo/pdf/id/643.html
Publisher Site
http://dx.doi.org/10.22608/APO.2018414DOI Listing
March 2019
11 Reads

ACUTE MYOCARDITIS WITH CARDIOGENIC SHOCK AND MULTIPLE ORGAN FAILURE, FOLLOWED BY BILATERAL PANUVEITIS MASQUERADING AS ENDOGENOUS ENDOPHTHALMITIS, DUE TO TOXOPLASMA GONDII IN AN IMMUNOCOMPETENT PATIENT.

Retin Cases Brief Rep 2019 Jan 17. Epub 2019 Jan 17.

Massachusetts Eye Research and Surgery Institution (MERSI), Waltham, Massachusetts.

Purpose: To report a case of systemic and ocular toxoplasmosis in an immunocompetent patient, who developed myocarditis with resulting cardiogenic shock and multiple organ failure, followed by bilateral panuveitis masquerading as endogenous endophthalmitis.

Methods: Single case report with images.

Results: A 59-year-old man with a history of monoclonal gammopathy of undetermined significance and associated scleromyxedema but otherwise immunocompetent was admitted to the intensive care unit for cardiogenic shock and multiple organ failure due to presumed viral myocarditis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/ICB.0000000000000855DOI Listing
January 2019
5 Reads

Postoperative Mycobacteroides abscessus subsp. abscessus endophthalmitis: Clinical analysis of 12 clustered adults and a proposed therapeutic algorithm.

J Microbiol Immunol Infect 2019 Jan 6. Epub 2019 Jan 6.

Department of Ophthalmology, Taipei Medical University Hospital, Taipei, Taiwan; Department of Ophthalmology, School of Medicine, College of Medicine, Taipei Medical University, Taiwan. Electronic address:

Purpose: Postoperative endophthalmitis caused by nontuberculous mycobacterium is a rare but devastating complication after intraocular surgery. However, optimal treatment strategies remain undetermined in view of its rarity.

Methods: We investigated the cases of culture-proven postoperative Mycobacteroides abscessus subsp. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmii.2018.12.011DOI Listing
January 2019
1 Read

A Case Report of Endogenous Endophthalmitis in the Setting of Nocardia kroppenstedtii Infection.

Ophthalmic Surg Lasers Imaging Retina 2019 01;50(1):53-55

A woman with a past medical history of radiation and chemotherapy for multiple malignancies presented with bilateral, multifocal, elevated chorioretinal lesions associated with vitritis. The differential diagnosis included endogenous endophthalmitis and metastatic disease. Her extensive medical history and ill appearance at presentation in concert with vitritis and subretinal lesions was concerning for endogenous endophthalmitis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3928/23258160-20181212-09DOI Listing
January 2019
2 Reads

Culture-Proven Endophthalmitis After Intravitreal Injection: A 10-Year Analysis.

Ophthalmic Surg Lasers Imaging Retina 2019 01;50(1):33-38

Background And Objective: To report on the microbiology, management, and visual outcomes of intravitreal injection (IVI)-associated, culture-proven endophthalmitis.

Patients And Methods: All patients seen at a tertiary referral center with culture-proven endophthalmitis associated with an IVI between June 2007 and July 2017 were included in this retrospective analysis.

Results: Thirty-five patients with culture-positive endophthalmitis following IVI were identified. Read More

View Article

Download full-text PDF

Source
https://www.healio.com/doiresolver?doi=10.3928/23258160-2018
Publisher Site
http://dx.doi.org/10.3928/23258160-20181212-05DOI Listing
January 2019
12 Reads

Effect of time to primary repair on final visual outcome after open globe injury.

Br J Ophthalmol 2019 Jan 12. Epub 2019 Jan 12.

Academic Unit of Ophthalmology, Birmingham and Midland Eye Centre, City Hospital, Birmingham, UK.

Background/aim: Historic data suggest that open globe injuries should be repaired within 12-24 hours to reduce the risk of endophthalmitis. However, endophthalmitis is uncommon when systemic antibiotic prophylaxis is given. It is not clear whether delayed primary repair impacts visual outcomes in other ways or what is the optimum time to repair. Read More

View Article

Download full-text PDF

Source
http://bjo.bmj.com/lookup/doi/10.1136/bjophthalmol-2017-3115
Publisher Site
http://dx.doi.org/10.1136/bjophthalmol-2017-311559DOI Listing
January 2019
19 Reads

Ocular infection caused by Hormographiella aspergillata: A case report and review of literature.

J Mycol Med 2019 Apr 7;29(1):71-74. Epub 2019 Jan 7.

Department of Medical Microbiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Hormographiella aspergillata, a basidiomycete is a rare cause of human infection. We report a case of 70-year-old female with corneal ulcer and endophthalmitis caused by this agent. The patient had an intraocular implantation of lens following a cataract surgery. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S11565233183024
Publisher Site
http://dx.doi.org/10.1016/j.mycmed.2018.12.002DOI Listing
April 2019
11 Reads

Diagnosis of Vitreoretinal Aspergillosis with Transvitreal Retinochoroidal Biopsy.

Case Rep Ophthalmol Med 2018 2;2018:8306163. Epub 2018 Dec 2.

Department of Ophthalmology, Drexel University College of Medicine, Philadelphia, PA, USA.

Diagnosing culture-proven endophthalmitis is complicated by the insufficient yield of intraocular samples and the variety of etiologies which mimic true endophthalmitis. In cases of impending vision loss where vitreous biopsy cannot provide a definitive diagnosis, transvitreal retinochoroidal biopsy can be an effective next step. Our case is a 48-year-old male with B-cell acute lymphoblastic leukemia that presented with counting fingers vision, redness, and tearing of the left eye. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2018/8306163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304639PMC
December 2018
9 Reads

Antibiotic susceptibility, cytotoxicity, and protease activity of viridans group streptococci causing endophthalmitis.

PLoS One 2018 21;13(12):e0209849. Epub 2018 Dec 21.

Department of Pathology, University of Mississippi Medical Center, Jackson, Mississippi, United States of America.

The viridans group streptococci comprise multiple species and have gained more recognition in recent years as common etiologic agents of bacterial endophthalmitis. The purpose of this study was to identify the species of human endophthalmitis isolates of viridans streptococci and to characterize their potential virulence attributes. The species of 22 endophthalmitis strains of viridans streptococci were identified by Matrix Assisted Laser Desorption Ionization Time-of-Flight. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0209849PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303072PMC
December 2018
13 Reads

Acute subretinal abscess in septicaemia with endophthalmitis showcased by multimodal retinal imaging and with 2-year follow-up.

BMJ Case Rep 2018 11 28;11(1). Epub 2018 Nov 28.

Department of Ophthalmology, Royal Bolton Hospital NHS Foundation Trust, Bolton, UK.

A middle-aged man presented to emergency services with central vision loss in the setting of flu-like illness with fever. A striking subfoveal abscess was observed in the right fundus. Focal acute chorioretinal inflammation was noted in the asymptomatic fellow eye. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2018-227288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301446PMC
November 2018

Hypermucoviscous capsular 1 (K1) serotype necrotising fasciitis and metastatic endophthalmitis.

BMJ Case Rep 2018 Nov 28;11(1). Epub 2018 Nov 28.

Section of Infectious Diseases, Department of Medicine, College of Medicine & Philippine General Hospital, University of the Philippines Manila, Manila, Philippines.

A 48-year-old man presented with a non-healing wound on his left foot after stepping on a nail. He self-medicated with amoxicillin, but the wound progressed prompting consult. On examination, his left foot was diffusely swollen with surrounding erythema, areas of gangrene, foul-smelling purulent discharge and subcutaneous emphysema. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2018-226096DOI Listing
November 2018
3 Reads

Fungal infection after endothelial keratoplasty: association with hypothermic corneal storage.

Br J Ophthalmol 2018 Dec 18. Epub 2018 Dec 18.

Corneal Service, Moorfields Eye Hospital NHS Foundation Trust, London, UK

Purpose: To compare the incidence of fungal infection after endothelial keratoplasty (EK) when donor tissue had been stored in hypothermic medium or organ culture.

Methods: We describe the clinical features of 10 cases of fungal infection (keratitis or endophthalmitis) following EK identified at three European centres. Case definition was the culture of fungus or a positive PCR from the host cornea or anterior chamber after EK. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bjophthalmol-2018-312709DOI Listing
December 2018
7 Reads

Unilateral endogenous fungal endophthalmitis after esophageal cancer surgery: a case report.

BMC Infect Dis 2018 Dec 18;18(1):671. Epub 2018 Dec 18.

Department of Ophthalmology, Ningbo Eye Hospital, 855 Minan Road, Ningbo, 315040, China.

Background: This study reports a case of Unilateral Endogenous Fungal Endophthalmitis After Esophageal Cancer Surgery.

Case Presentation: One patient presented with a month-long loss of vision in his left eye, he had surgery for esophageal cancer 2 months earlier. The patient underwent cataract surgery (by phacoemulsification) in the left eye combined with 25-gauge vitrectomy and silicone oil tamponade. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12879-018-3607-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299646PMC
December 2018
2 Reads

Endogenous endophthalmitis caused by a multidrug-resistant hypervirulent Klebsiella pneumoniae strain belonging to a novel single locus variant of ST23: first case report in China.

BMC Infect Dis 2018 Dec 17;18(1):669. Epub 2018 Dec 17.

Department of Respiratory Diseases, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.

Background: Endogenous endophthalmitis caused by hypervirulent Klebsiella pneumoniae (HVKP) is an emerging infectious disease commonly with a devastating visual outcome. Most HVKP strains display a wild-type susceptibility profile to antibiotics. However, reports of antimicrobial-resistant HVKP have increased over time, which poses a serious therapeutic dilemma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12879-018-3543-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296127PMC
December 2018
3 Reads

The Role of Pneumococcal Virulence Factors in Ocular Infectious Diseases.

Interdiscip Perspect Infect Dis 2018 13;2018:2525173. Epub 2018 Nov 13.

Department of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, MS 39216, USA.

is a gram-positive, facultatively anaerobic pathogen that can cause severe infections such as pneumonia, meningitis, septicemia, and middle ear infections. It is also one of the top pathogens contributing to bacterial keratitis and conjunctivitis. Though two pneumococcal vaccines exist for the prevention of nonocular diseases, they do little to fully prevent ocular infections. Read More

View Article

Download full-text PDF

Source
https://www.hindawi.com/journals/ipid/2018/2525173/
Publisher Site
http://dx.doi.org/10.1155/2018/2525173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257906PMC
November 2018
12 Reads

A Review of Antimicrobial Therapy for Infectious Uveitis of the Posterior Segment.

Med Hypothesis Discov Innov Ophthalmol 2018 ;7(4):140-155

UCL Institute of Ophthalmology, Moorfields Eye Hospital, London, UK.

Treatment of infectious posterior uveitis represents a therapeutic challenge for ophthalmologists. The eye is a privileged site, maintained by blood ocular barriers, which limits penetration of systemic antimicrobials into the posterior segment. In addition, topical and subconjunctival therapies are incapable of producing sufficient drug concentrations, intraocularly. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6229674PMC
January 2018
5 Reads

Challenges in the Polyene- and Azole-Based Pharmacotherapy of Ocular Fungal Infections.

J Ocul Pharmacol Ther 2019 Jan/Feb;35(1):6-22. Epub 2018 Nov 8.

1 Department of Pharmaceutics and Drug Delivery, School of Pharmacy, University of Mississippi, Oxford, Mississippi.

Polyenes and azoles constitute 2 major drug classes in the antifungal armamentarium used to treat fungal infections of the eye such as fungal keratitis, endophthalmitis, conjunctivitis, and blepharitis. These classes of drugs have come to occupy an important niche in ophthalmic antifungal therapy due to their broad spectrum of activity against a variety of filamentous and yeast-like fungi. Natamycin suspension (Natacyn), a polyene antifungal drug, is currently the only US FDA-approved formulation for treating ophthalmic fungal infections, whereas the other polyene and azole antifungals such as amphotericin B, fluconazole, itraconazole, ketoconazole, miconazole, voriconazole, and posaconazole are routinely used off-label in the clinical setting. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/jop.2018.0089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354613PMC
November 2018
20 Reads

The role of pars plana vitrectomy in the management of fungal endogenous endophthalmitis.

Eur J Ophthalmol 2018 Nov 26:1120672118815105. Epub 2018 Nov 26.

Department of Ophthalmology, School of Medicine, Marmara University, Istanbul, Turkey.

Purpose:: To identify the causative microorganism of fungal endogenous endophthalmitis in our tertiary referral uveitis center and review the therapeutic role of pars plana vitrectomy in patients with fungal endogenous endophthalmitis.

Methods:: Seven eyes of six cases were identified as fungal endogenous endophthalmitis through positive cultures of ocular fluids and clinical presentations. The final anatomical and functional results were evaluated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1120672118815105DOI Listing
November 2018
13 Reads

Clinical presentations, management outcomes, and diagnostic dilemma in Kocuria endophthalmitis.

J Ophthalmic Inflamm Infect 2018 Nov 20;8(1):21. Epub 2018 Nov 20.

Smt. Kanuri Santhamma Center for Vitreoretinal Diseases, Kallam Anji Reddy Campus, LV Prasad Eye Institute, Hyderabad, Telangana, 500034, India.

Aim: To describe the clinical presentations and management outcomes of Kocuria endophthalmitis and discuss diagnostic dilemmas DESIGN: Retrospective interventional comparative case series INTERVENTION: Eight unilateral cases with culture-proven Kocuria endophthalmitis from January 2013 to December 2017 underwent vitrectomy/vitreous biopsy and intravitreal antibiotic with or without additional procedures. The undiluted vitreous was subjected to microbiologic evaluation.

Main Outcome Measures: The mean age at presentation, etiology, number of interventions, interval between inciting event and presentation, type of intravitreal antibiotic used, and anatomic and functional outcomes were reported. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12348-018-0163-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246755PMC
November 2018
17 Reads

Abdominal Septic Shock: An Eye-Popping Case.

Gastroenterology 2019 03 13;156(4):881-882. Epub 2018 Nov 13.

Ospedale Niguarda Ca' Granda Milano, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2018.10.055DOI Listing

Cluster endophthalmitis due to following intravitreal bevacizumab: outcomes of patients from North India.

Br J Ophthalmol 2018 Nov 12. Epub 2018 Nov 12.

Advanced Eye Center, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India

Purpose: To study features, management and outcomes of cluster endophthalmitis following intravitreal bevacizumab (BCZ) injection in North India.

Methods: In this retrospective study, 28 patients (23 men) (mean age of 59.07±13 years) who received intravitreal injection of BCZ were included. Read More

View Article

Download full-text PDF

Source
http://bjo.bmj.com/lookup/doi/10.1136/bjophthalmol-2018-3131
Publisher Site
http://dx.doi.org/10.1136/bjophthalmol-2018-313131DOI Listing
November 2018
9 Reads

CLINICAL PRESENTATIONS, DIAGNOSIS, AND MANAGEMENT OUTCOMES OF CURVULARIA ENDOPHTHALMITIS AND A REVIEW OF LITERATURE.

Retina 2018 Oct 23. Epub 2018 Oct 23.

Smt. Kanuri Santhamma Center for Vitreoretinal Diseases, LV Prasad Eye Institute, Hyderabad, India.

Purpose: To describe the clinical presentation and management of Curvularia endophthalmitis and compare with previous published literature.

Methods: Retrospective interventional comparative case series and literature review. Eight cases with culture-proven Curvularia endophthalmitis from January 2000 to March 2018 underwent vitrectomy/vitreous biopsy, intravitreal antibiotic with or without additional procedures as appropriate. Read More

View Article

Download full-text PDF

Source
http://Insights.ovid.com/crossref?an=00006982-900000000-9631
Publisher Site
http://dx.doi.org/10.1097/IAE.0000000000002375DOI Listing
October 2018
8 Reads

Identification of Species in a Patient with Endophthalmitis following Penetrating Injury with Retained Intraocular Metallic Foreign Body.

Case Rep Infect Dis 2018 25;2018:3027846. Epub 2018 Sep 25.

Department of Ophthalmology, Oslo University Hospital, Oslo, Norway.

To the best of our knowledge, we report the first case of species in a patient with endophthalmitis. A 47-year-old man presented to the ophthalmology department with decreased vision, redness, and minimal pain in his right eye after a foreign body struck his eye following working using a hammer and chisel. Broad-spectrum polymerase chain reaction (PCR) and deoxyribonucleic acid (DNA) sequencing targeting 16S ribosomal ribonucleic acid-(rRNA-) encoding gene on an undiluted vitreous sample revealed 100% identity with GenBank sequences of species including , , and . Read More

View Article

Download full-text PDF

Source
https://www.hindawi.com/journals/criid/2018/3027846/
Publisher Site
http://dx.doi.org/10.1155/2018/3027846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176285PMC
September 2018
13 Reads

Interface infectious keratitis after anterior and posterior lamellar keratoplasty. Clinical features and treatment strategies. A review.

Br J Ophthalmol 2019 Mar 24;103(3):307-314. Epub 2018 Oct 24.

Ophthalmology Unit, Azienda USL - IRCCS di Reggio Emilia, Reggio Emilia, Italy.

Interface infectious keratitis (IIK) is a novel corneal infection that may develop after any type of lamellar keratoplasty. Onset of infection occurs in the virtual space between the graft and the host where it may remain localised until spreading with possible risk of endophthalmitis. A literature review identified 42 cases of IIK. Read More

View Article

Download full-text PDF

Source
http://bjo.bmj.com/lookup/doi/10.1136/bjophthalmol-2018-3129
Publisher Site
http://dx.doi.org/10.1136/bjophthalmol-2018-312938DOI Listing
March 2019
14 Reads

Genetic diversity and persistent colonization of Enterococcus faecalis on ocular surfaces.

Jpn J Ophthalmol 2018 Nov 15;62(6):699-705. Epub 2018 Oct 15.

Department of Ophthalmology, Gunma University Graduate School of Medicine, 3-39-15 Showa-machi, Maebashi, Gunma, 371-8511, Japan.

Purpose: Enterococcus faecalis causes severe acute endophthalmitis and often leads to poor visual outcomes. Conjunctival bacterial cultures occasionally grow atypical bacteria including E. faecalis, which can potentially contribute to the development of postoperative endophthalmitis. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10384-018-0630-5
Publisher Site
http://dx.doi.org/10.1007/s10384-018-0630-5DOI Listing
November 2018
27 Reads

Complicated bilateral fungal emphysematous pyelonephritis in a 55-year-old diabetic female: A case report and review of literature.

Curr Med Mycol 2018 Jun;4(2):32-35

Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medial Sciences, Tehran, Iran.

Background And Purpose: Emphysematous pyelonephritis (EPN) is a rare and serious disease causing acute renal failure. Diabetes is a major risk factor for this infection.

Case Report: Herein, we present the case of a 55-year-old female patient with diabetes and EPN caused by . Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18502/cmm.4.2.61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181061PMC
June 2018
17 Reads

Chronic postcataract endophthalmitis caused by species in an immunocompetent patient.

Int Med Case Rep J 2018 8;11:259-262. Epub 2018 Oct 8.

Department of Ophthalmology, National Defense Medical College, Tokorozawa, Japan,

Objective: species are abundant, generally saprophytic, and widely distributed in the environment. On rare occasions, they cause endophthalmitis in immunocompromised patients or in immunocompetent patients with uncontrolled diabetic mellitus or immunosuppressive agents. We report a case of endophthalmitis caused by species in an immunocompetent patient without any disorders. Read More

View Article

Download full-text PDF

Source
https://www.dovepress.com/chronic-postcataract-endophthalmit
Publisher Site
http://dx.doi.org/10.2147/IMCRJ.S175374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181112PMC
October 2018
19 Reads