3,632 results match your criteria Endophthalmitis Bacterial


Utility of Ophthalmologic Screening for Patients With Candida Bloodstream Infections: A Systematic Review.

JAMA Ophthalmol 2019 Apr 18. Epub 2019 Apr 18.

Vanderbilt University School of Medicine, Nashville, Tennessee.

Importance: The Infectious Diseases Society of America recommends ophthalmologic examinations for everyone with positive Candida blood culture results (candidemia) to screen for endophthalmitis, a practice that remains controversial because of multiple concerns for its limited usefulness and potential for harm.

Objective: To determine guideline efficacy by reconciling discrepancies in the incidence of endophthalmitis and evaluating outcomes of studies assessing ophthalmologic screening for candidemia.

Evidence Review: PubMed literature searches, including the search terms candidemia, fungemia, chorioretinitis, and endophthalmitis, identified longitudinal studies prior to 2018 of patients who underwent ophthalmologic evaluations in the setting of positive fungal blood culture results regardless of symptoms or clinical status. Read More

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http://dx.doi.org/10.1001/jamaophthalmol.2019.0733DOI Listing

Comparative Study Between Topical Gatifloxacin 0.5% and Moxifloxacin 0.5% as a Prophylactic Measure Before Intraocular Surgery.

J Ocul Pharmacol Ther 2019 Apr 5. Epub 2019 Apr 5.

1 Department of Ophthalmology, Fayoum University Faculty of Medicine, Fayoum, Egypt.

Purpose: To compare equal concentrations (0.5%) of moxifloxacin and gatifloxacin ophthalmic solutions with regard to conjunctival bacterial reduction as well as anterior chamber penetration.

Methods: One hundred patients were divided into 2 groups. Read More

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http://dx.doi.org/10.1089/jop.2018.0088DOI Listing
April 2019
1 Read

A diagnostic dilemma in a patient with delayed onset endophthalmitis.

Saudi J Ophthalmol 2019 Jan-Mar;33(1):99-101. Epub 2018 Jul 9.

Department of Ophthalmology, Baskent University, Faculty of Medicine, Ankara, Turkey.

We report a case of nonpainful uveitis nine months after an uncomplicated phacoemulsification cataract surgery. Chronic postoperative endophthalmitis was suspected. Diagnostic vitrectomy and partial capsular bag removal was performed, but the specimens cultured in microbiology laboratory showed no pathogens. Read More

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http://dx.doi.org/10.1016/j.sjopt.2018.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424715PMC
July 2018
1 Read

[Endogenous endophthalmitis following staphylococcus aureus meningitis].

Rinsho Shinkeigaku 2019 Mar 30. Epub 2019 Mar 30.

Division of Ophthalmology, Nishi-Kobe Medical Center.

Endogenous endophthalmitis is a rare complication of acute meningitis. A healthy 82-year-old woman suddenly developed septic bacteremia and meningitis owing to Staphylococcus aureus (methicillin-susceptible Staphylococcus aureus); she presented with a high fever and drowsiness. Improvement of these initial symptoms unveiled impaired bilateral visual acuity. Read More

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http://dx.doi.org/10.5692/clinicalneurol.cn-001233DOI Listing
March 2019
2 Reads

Characteristics and Outcomes of Endogenous Endophthalmitis: Eight-Year Experience at a Tertiary Care Center.

Ophthalmol Retina 2019 Jan 6;3(1):61-72. Epub 2018 Sep 6.

Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts. Electronic address:

Purpose: To describe the characteristics and outcomes of endogenous endophthalmitis.

Design: Retrospective case series.

Participants: Patients with endogenous endophthalmitis. Read More

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http://dx.doi.org/10.1016/j.oret.2018.08.009DOI Listing
January 2019
2 Reads

Sticky Business: a syndrome of mucoid bacterial spread.

BMJ Case Rep 2019 Mar 22;12(3). Epub 2019 Mar 22.

Division of Infectious Diseases, California Pacific Medical Center, San Francisco, California, USA.

A 70-year-old man presented with acute wrist pain concerning for septic arthritis. Shortly thereafter, he developed acute monocular vision loss and was diagnosed with endogenous endophthalmitis. Subsequent imaging revealed numerous visceral abscesses and a mycotic abdominal aortic aneurysm. Read More

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http://dx.doi.org/10.1136/bcr-2018-226956DOI Listing
March 2019
1 Read

ENDOGENOUS ENDOPHTHALMITIS IN WESTERN AUSTRALIA: A Sixteen-Year Retrospective Study.

Retina 2019 Mar 12. Epub 2019 Mar 12.

Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth, Western Australia, Australia.

Purpose: To review the clinical features, microbiology spectrum, management, and outcomes of patients with endogenous endophthalmitis in Western Australia over a 16-year period.

Methods: This is a retrospective chart review of all patients with endogenous endophthalmitis who presented to all tertiary ophthalmology departments between 2000 and 2015 in Western Australia.

Results: Sixty-six eyes of 57 patients with endogenous endophthalmitis were identified, and follow-up data were available for a mean of 554 days. Read More

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http://dx.doi.org/10.1097/IAE.0000000000002512DOI Listing
March 2019
11 Reads

Endophthalmitis following Suture Removal - Clinical Outcomes and Microbiological Profile.

Semin Ophthalmol 2019 16;34(2):115-123. Epub 2019 Mar 16.

b Smt Kanuri Santhamma Center for Vitreo- Retina diseases , Hyderabad , India.

Aims: To review the clinical profile and report the microbiology and treatment outcomes of endophthalmitis following suture removal.

Methods: In this multi-center, retrospective interventional case series, 11 eyes of 11 patients who developed endophthalmitis following suture removal from January 2006 to December 2017 were reviewed.

Results: Nine of the 11 patients developed a culture-proven, acute onset endophthalmitis [5. Read More

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http://dx.doi.org/10.1080/08820538.2019.1590605DOI Listing
April 2019
1 Read
1.196 Impact Factor

Endophthalmitis associated with fungal keratitis and penetrating injuries in North China.

Eur J Ophthalmol 2019 Mar 4:1120672119833896. Epub 2019 Mar 4.

3 Clinical Lab of Qilu Hospital (Qingdao), Shandong University, Qingdao, P.R.China.

Purpose:: To report the laboratory findings, management strategies, and visual outcomes of culture-proven exogenous fungal endophthalmitis in North China.

Methods:: The microbiological and treatment records of patients with culture-positive exogenous fungal endophthalmitis who visited the Affiliated Hospital of Qingdao University from January 2012 to December 2016 were reviewed.

Results:: A total of 39 eyes (39 patients) were identified over a 5-year period. Read More

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http://dx.doi.org/10.1177/1120672119833896DOI Listing
March 2019
3 Reads

The effect of diluting povidone-iodine on bacterial growth associated with speech.

BMC Ophthalmol 2019 Feb 26;19(1):62. Epub 2019 Feb 26.

Centre For Eye Research Australia, The Royal Victorian Eye and Ear Hospital, University of Melbourne, 32 Gisborne Street, East Melbourne, Victoria, 3002, Australia.

Background: Povidone-Iodine (PI) may be diluted when used as an antiseptic prior to an intravitreal injection in an attempt to decrease patient discomfort. This study aims to investigate the effect of diluting povidone-iodine (PI) on bacterial growth from bacterial droplet dispersal associated with speech.

Methods: Participants read a standardised script for 5 min over a blood agar plate positioned at 20 cm in a simulated position of an intravitreal injection procedure. Read More

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http://dx.doi.org/10.1186/s12886-019-1066-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390624PMC
February 2019
2 Reads

Klebsiella Pneumoniae Endogenous Endophthalmitis Mimicking a Choroidal Neovascular Membrane with Subretinal Hemorrhage.

Ocul Immunol Inflamm 2019 Feb 26:1-3. Epub 2019 Feb 26.

a Advanced Eye Centre , Post Graduate Institute of Medical Education and Research , Chandigarh , India.

Background: Klebsiella endogenous endophthalmitis (EE) is commonly seen in patients with hepato-biliary disease and urinary tract infections. Subretinal abscess with vitreous cells is the usual presentation and requires intensive treatment with systemic and intravitreal antibiotics along with prompt vitrectomy. Subretinal hemorrhage surrounding a choroidal mass has not been reported as the presenting feature of endogenous bacterial endophthalmitis. Read More

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http://dx.doi.org/10.1080/09273948.2019.1569695DOI Listing
February 2019

Iris melanin pigment as a masquerade of Gram-positive cocci after penetrating ocular trauma.

Digit J Ophthalmol 2018 18;24(4):27-30. Epub 2018 Oct 18.

Department of Ophthalmology, University of North Carolina, Chapel Hill, North Carolina.

We describe a case of penetrating eye injury that resulted in a post-injury day 1 hypopyon, leading to concern for endophthalmitis and phacoanaphylaxis. A Gram stain prepared by the clinical microbiology laboratory was interpreted as Gram-positive cocci (GPC). However, when cultures returned negative, further investigation with microbiology and pathology found that what was thought to be GPC was actually iris melanin pigment. Read More

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http://dx.doi.org/10.5693/djo.02.2018.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380259PMC
March 2019
1 Read

Revisiting systemic treatment of bacterial endophthalmitis: a review of intravitreal penetration of systemic antibiotics.

Clin Microbiol Infect 2019 Feb 14. Epub 2019 Feb 14.

Division of Infectious Diseases and Hospital Epidemiology, Departments of Medicine and Clinical Research, University Hospital of Basel and University of Basel, Basel, Switzerland.

Background: Adjunctive systemic antibiotic therapy for treatment of bacterial endophthalmitis is controversial but common practice due to the severity of the disease. In the absence of guidance documents, several antibiotic regimens are being used without applying evidence-based prescribing, leading to inappropriate treatment of this serious eye condition.

Objectives: To summarize available data on intravitreal penetration of systemically administered antibiotics and to discuss their usefulness from a microbiological and pharmacological point of view. Read More

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http://dx.doi.org/10.1016/j.cmi.2019.01.017DOI Listing
February 2019
1 Read

Subretinal Hypopyon in Presumed Tubercular Uveitis: A Report of Two Cases.

Middle East Afr J Ophthalmol 2018 Jul-Dec;25(3-4):163-166

Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Subretinal hypopyon is an uncommon entity which has been described in ocular infections and inflammations including endophthalmitis, acute retinal necrosis, and sympathetic ophthalmia. The authors report subretinal hypopyon in two cases of presumed tubercular uveitis which responded well to antitubercular therapy (ATT). The first case was a 47-year-old male with bilateral peripapillary chorioretinitis with a subretinal hypopyon. Read More

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http://dx.doi.org/10.4103/meajo.MEAJO_187_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348936PMC

Impact of antibiotic resistance of pathogens and early vitrectomy on the prognosis of infectious endophthalmitis: a 10-year retrospective study.

Graefes Arch Clin Exp Ophthalmol 2019 Apr 13;257(4):805-813. Epub 2019 Feb 13.

Department of Ophthalmology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211, Eonjuro, Gangnam-gu, Seoul, 135-720, South Korea.

Purpose: Infectious endophthalmitis (IE) is a severe complication that can lead to blindness even with treatment. However, the impact of antibiotic resistance and early vitrectomy on its prognosis has scarcely been documented. This study investigated the impact of antibiotic resistance of pathogen and early vitrectomy on the prognosis of IE. Read More

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http://dx.doi.org/10.1007/s00417-019-04261-xDOI Listing
April 2019
1 Read
1.908 Impact Factor

endophthalmitis in a Cuban pediatric patient.

SAGE Open Med Case Rep 2019 30;7:2050313X19827403. Epub 2019 Jan 30.

Pedro Kourí Tropical Medicine Institute, La Habana, Cuba.

Bacterial endophthalmitis is the most severe form of vision-threatening ocular infection. is a primary respiratory pathogen that has been associated with several extrapulmonary manifestation, including ocular infection. In this work, we presented the microbiology diagnosis of an endophalmitis by using a novel A. Read More

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http://dx.doi.org/10.1177/2050313X19827403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354299PMC
January 2019
1 Read

New insights into culture negative endophthalmitis by unbiased next generation sequencing.

Sci Rep 2019 Jan 29;9(1):844. Epub 2019 Jan 29.

Jhaveri Microbiology Centre, Brien Holden Eye Research Centre, L. V. Prasad Eye Institute, Hyderabad, Telangana, India.

The proof-of-concept, study to investigate the presence of microorganisms in presumed infectious endophthalmitis using Next generation sequencing (NGS) was carried out in vitreous biopsies from 34 patients with endophthalmitis, and thirty patients undergoing surgery for non-infectious retinal disorders as controls. Following DNA extraction using the Qiagen mini kit and PCR amplification of the V3-V4 regions of the bacterial 16S rRNA and ITS 2 region of fungus, they samples were sequenced on an Illumina HiSeq 2500 Machine. Paired reads were curated, taxonomically labeled, and filtered. Read More

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http://www.nature.com/articles/s41598-018-37502-w
Publisher Site
http://dx.doi.org/10.1038/s41598-018-37502-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351655PMC
January 2019
12 Reads

Incidence of acute-onset endophthalmitis after separate bilateral cataract surgeries less than 5 days apart.

BMC Ophthalmol 2019 Jan 25;19(1):32. Epub 2019 Jan 25.

Department of Ophthalmology, Xi'an No. 4 Hospital, Shaanxi Eye Hospital, Affiliated Guangren Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, 710004, Shaanxi Province, China.

Purpose: To assess the incidence of acute-onset endophthalmitis after separate bilateral cataract surgeries less than 5 days apart (SBCS5).

Methods: The medical records of all patients who underwent SBCS5 at a single medical center between October 10, 2012 and July 31, 2017 were retrospectively reviewed.

Results: The medical records for treatment of 5374 eyes of 2687 patients were examined. Read More

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http://dx.doi.org/10.1186/s12886-019-1028-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347771PMC
January 2019
13 Reads

Early Pars Plana Vitrectomy for Treatment of Acute Infective Endophthalmitis.

Asia Pac J Ophthalmol (Phila) 2019 Jan-Feb;8(1):3-7. Epub 2019 Jan 22.

Retina Unit, Sydney Eye Hospital, Sydney, NSW, Australia.

Purpose: To evaluate the efficacy and safety of early pars plana vitrectomy (PPV) for the treatment of acute infective endophthalmitis, and identify prognostic factors for better visual outcome.

Design: Retrospective cohort study.

Methods: Consecutive patients who underwent early PPV within 72 hours of presentation for the treatment of acute infective bacterial endophthalmitis and presented to a large tertiary referral center in New South Wales, Australia, between January 2009 and December 2013 were included. Read More

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http://www.apjo.org/Apjo/pdf/id/643.html
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http://dx.doi.org/10.22608/APO.2018414DOI Listing
March 2019
11 Reads

A Case Report of Endogenous Endophthalmitis in the Setting of Nocardia kroppenstedtii Infection.

Ophthalmic Surg Lasers Imaging Retina 2019 01;50(1):53-55

A woman with a past medical history of radiation and chemotherapy for multiple malignancies presented with bilateral, multifocal, elevated chorioretinal lesions associated with vitritis. The differential diagnosis included endogenous endophthalmitis and metastatic disease. Her extensive medical history and ill appearance at presentation in concert with vitritis and subretinal lesions was concerning for endogenous endophthalmitis. Read More

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http://dx.doi.org/10.3928/23258160-20181212-09DOI Listing
January 2019
2 Reads

Culture-Proven Endophthalmitis After Intravitreal Injection: A 10-Year Analysis.

Ophthalmic Surg Lasers Imaging Retina 2019 01;50(1):33-38

Background And Objective: To report on the microbiology, management, and visual outcomes of intravitreal injection (IVI)-associated, culture-proven endophthalmitis.

Patients And Methods: All patients seen at a tertiary referral center with culture-proven endophthalmitis associated with an IVI between June 2007 and July 2017 were included in this retrospective analysis.

Results: Thirty-five patients with culture-positive endophthalmitis following IVI were identified. Read More

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https://www.healio.com/doiresolver?doi=10.3928/23258160-2018
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http://dx.doi.org/10.3928/23258160-20181212-05DOI Listing
January 2019
12 Reads

The Early Diagnosis of Endophthalmitis Due to Group B Streptococcus Infective Endocarditis and Its Clinical Course: A Case Report and Literature Review.

Intern Med 2019 Jan 10. Epub 2019 Jan 10.

Division of Cardiovascular Medicine, Department of Internal Medicine, Jichi Medical University School of Medicine, Japan.

A 68-year-old Japanese man was admitted to our hospital with right eye pain, a sudden worsening of his eyesight, and a fever. He was diagnosed with endogenous bacterial endophthalmitis due to infectious endocarditis (IE) of Group B Streptococcus (GBS) on the day of admission. He recovered systemically, but his right eye became phthisical only with the administration of antibiotics. Read More

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http://dx.doi.org/10.2169/internalmedicine.2232-18DOI Listing
January 2019
3 Reads

Antibiotic susceptibility, cytotoxicity, and protease activity of viridans group streptococci causing endophthalmitis.

PLoS One 2018 21;13(12):e0209849. Epub 2018 Dec 21.

Department of Pathology, University of Mississippi Medical Center, Jackson, Mississippi, United States of America.

The viridans group streptococci comprise multiple species and have gained more recognition in recent years as common etiologic agents of bacterial endophthalmitis. The purpose of this study was to identify the species of human endophthalmitis isolates of viridans streptococci and to characterize their potential virulence attributes. The species of 22 endophthalmitis strains of viridans streptococci were identified by Matrix Assisted Laser Desorption Ionization Time-of-Flight. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0209849PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303072PMC
December 2018
13 Reads

Acute subretinal abscess in septicaemia with endophthalmitis showcased by multimodal retinal imaging and with 2-year follow-up.

BMJ Case Rep 2018 11 28;11(1). Epub 2018 Nov 28.

Department of Ophthalmology, Royal Bolton Hospital NHS Foundation Trust, Bolton, UK.

A middle-aged man presented to emergency services with central vision loss in the setting of flu-like illness with fever. A striking subfoveal abscess was observed in the right fundus. Focal acute chorioretinal inflammation was noted in the asymptomatic fellow eye. Read More

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http://dx.doi.org/10.1136/bcr-2018-227288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301446PMC
November 2018

Endogenous endophthalmitis caused by a multidrug-resistant hypervirulent Klebsiella pneumoniae strain belonging to a novel single locus variant of ST23: first case report in China.

BMC Infect Dis 2018 Dec 17;18(1):669. Epub 2018 Dec 17.

Department of Respiratory Diseases, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.

Background: Endogenous endophthalmitis caused by hypervirulent Klebsiella pneumoniae (HVKP) is an emerging infectious disease commonly with a devastating visual outcome. Most HVKP strains display a wild-type susceptibility profile to antibiotics. However, reports of antimicrobial-resistant HVKP have increased over time, which poses a serious therapeutic dilemma. Read More

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http://dx.doi.org/10.1186/s12879-018-3543-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296127PMC
December 2018
3 Reads

The Role of Pneumococcal Virulence Factors in Ocular Infectious Diseases.

Interdiscip Perspect Infect Dis 2018 13;2018:2525173. Epub 2018 Nov 13.

Department of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, MS 39216, USA.

is a gram-positive, facultatively anaerobic pathogen that can cause severe infections such as pneumonia, meningitis, septicemia, and middle ear infections. It is also one of the top pathogens contributing to bacterial keratitis and conjunctivitis. Though two pneumococcal vaccines exist for the prevention of nonocular diseases, they do little to fully prevent ocular infections. Read More

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https://www.hindawi.com/journals/ipid/2018/2525173/
Publisher Site
http://dx.doi.org/10.1155/2018/2525173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257906PMC
November 2018
12 Reads

Complete Genome Sequence of Massilia oculi sp. nov. CCUG 43427 (=DSM 26321), the Type Strain of M. oculi, and Comparison with Genome Sequences of Other Massilia Strains.

Curr Microbiol 2018 Nov 15. Epub 2018 Nov 15.

Key Laboratory of Urban Agriculture by Ministry of Agriculture of China, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.

Massilia oculi sp. nov. of type strain CCUG 43427 is a Gram-negative, rod-shaped, nonspore-forming bacterium, which was recently isolated from the eye of a patient suffering from endophthalmitis and was described as novel species in Massilia genus. Read More

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http://dx.doi.org/10.1007/s00284-018-1597-7DOI Listing
November 2018
3 Reads

Infectious postoperative endophthalmitis after cataract surgery performed over 7 years. The role of azithromycin versus ciprofloxacin eye drops.

Rev Esp Quimioter 2018 12 31;31(6):15-21. Epub 2018 Oct 31.

Santiago Grau Department of Pharmacy, Hospital del Mar, Parc de Salut Mar, Universitat Autònoma de Barcelona, Spain.

Objective: Although topical antibiotics have been used as antimicrobial prophylaxis after ocular surgery, recent studies have determined that intracameral cefuroxime at the end of surgery significantly reduce the risk to suffer an infection and suggest that the use of topical antibiotics in the prophylaxis of infectious postoperative endophthalmitis (IPOE) is controversial. Moreover, there is no evidence to confirm the higher effectiveness of topical ciprofloxacin, considered the standard of care, or topical azithromycin in preventing IPOE of cataract surgeries.

Methods: IPOE topical prophylaxis was performed with two different strategies: with azithromycin from January 1st, 2010 to December 31st, 2014 (group I) and with ciprofloxacin from January 1st, 2015 to January 31st, 2017 (group II). Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254483PMC
December 2018
7 Reads

[Vitrectomy for endophthalmitis : Incubation time and prognosis following intravitreal injection vs. cataract surgery].

Ophthalmologe 2018 Nov 12. Epub 2018 Nov 12.

Klinik für Augenheilkunde, Akademisches Lehrkrankenhaus der Johannes Gutenberg-Universität Mainz und der Medizinischen Fakultät Mannheim der Universität Heidelberg, Klinikum Ludwigshafen am Rhein, Bremserstr. 79, 67063, Ludwigshafen am Rhein, Deutschland.

Background: Bacterial endophthalmitis is a rare but devastating complication following intraocular surgery. Guidelines on the diagnostics and treatment are based mainly on experience of endophthalmitis treatment following cataract surgery.

Objective: In this study we analyzed infectious endophthalmitis cases following either intravitreal operative drug injection (IVOM) or cataract surgery for possible differences in the clinical course and prognosis. Read More

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http://dx.doi.org/10.1007/s00347-018-0816-8DOI Listing
November 2018
3 Reads

Orbital Cellulitis: Clinical Manifestations and Outcomes in a Tertiary Medical Center in Taiwan.

J Ophthalmol 2018 2;2018:4237573. Epub 2018 Oct 2.

Department of Ophthalmology, Chang Gung Memorial Hospital Linkou Branch, Taoyuan, Taiwan.

Purpose: To report six cases of orbital cellulitis without preceding endophthalmitis.

Method: Retrospective chart review.

Results: We reported four females and two males admitted to our hospital for orbital cellulitis proven by computed tomographies and bacterial cultures from May 1995 to March 2017. Read More

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https://www.hindawi.com/journals/joph/2018/4237573/
Publisher Site
http://dx.doi.org/10.1155/2018/4237573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189659PMC
October 2018
12 Reads

Genetic diversity and persistent colonization of Enterococcus faecalis on ocular surfaces.

Jpn J Ophthalmol 2018 Nov 15;62(6):699-705. Epub 2018 Oct 15.

Department of Ophthalmology, Gunma University Graduate School of Medicine, 3-39-15 Showa-machi, Maebashi, Gunma, 371-8511, Japan.

Purpose: Enterococcus faecalis causes severe acute endophthalmitis and often leads to poor visual outcomes. Conjunctival bacterial cultures occasionally grow atypical bacteria including E. faecalis, which can potentially contribute to the development of postoperative endophthalmitis. Read More

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http://link.springer.com/10.1007/s10384-018-0630-5
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http://dx.doi.org/10.1007/s10384-018-0630-5DOI Listing
November 2018
27 Reads

Chronic postcataract endophthalmitis caused by species in an immunocompetent patient.

Int Med Case Rep J 2018 8;11:259-262. Epub 2018 Oct 8.

Department of Ophthalmology, National Defense Medical College, Tokorozawa, Japan,

Objective: species are abundant, generally saprophytic, and widely distributed in the environment. On rare occasions, they cause endophthalmitis in immunocompromised patients or in immunocompetent patients with uncontrolled diabetic mellitus or immunosuppressive agents. We report a case of endophthalmitis caused by species in an immunocompetent patient without any disorders. Read More

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https://www.dovepress.com/chronic-postcataract-endophthalmit
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http://dx.doi.org/10.2147/IMCRJ.S175374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181112PMC
October 2018
19 Reads

Utility of broad-range 16S rRNA PCR assay versus conventional methods for laboratory diagnosis of bacterial endophthalmitis in a tertiary care hospital.

Br J Ophthalmol 2019 Jan 12;103(1):152-156. Epub 2018 Oct 12.

Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.

Background: Endophthalmitis, a sight-threatening intraocular infection, can be of postsurgical, post-traumatic or endogenous origin. Laboratory diagnosis-based appropriate therapy can be vision-saving. Conventional culture-based laboratory diagnosis takes time and lacks sensitivity. Read More

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http://bjo.bmj.com/lookup/doi/10.1136/bjophthalmol-2018-3128
Publisher Site
http://dx.doi.org/10.1136/bjophthalmol-2018-312877DOI Listing
January 2019
3 Reads

Filamentous gram-negative bacteria masquerading as actinomycetes in infectious endophthalmitis: a review of three cases.

J Ophthalmic Inflamm Infect 2018 Oct 11;8(1):15. Epub 2018 Oct 11.

Smt. Kanuri Santhamma Centre for Vitreo-Retinal Diseases, L. V. Prasad Eye Institute, Hyderabad, India.

Background: To report microbiological diagnostic dilemma posed by observation of unusual morphology of bacteria in the vitreous sample of a series of three cases of bacterial endophthalmitis.

Results: A non-comparative, descriptive case series is described. All three cases presented to the retina-vitreous clinic with a clinical diagnosis of acute endophthalmitis between January and April 2018. Read More

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https://joii-journal.springeropen.com/articles/10.1186/s1234
Publisher Site
http://dx.doi.org/10.1186/s12348-018-0157-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179972PMC
October 2018
8 Reads

Elevated cytokine levels in vitreous as biomarkers of disease severity in infectious endophthalmitis.

PLoS One 2018 8;13(10):e0205292. Epub 2018 Oct 8.

Jhaveri Microbiology Centre, Brien Holden Eye Research Centre, L. V. Prasad Eye Institute, Hyderabad, Telangana, India.

Purpose: To investigate the immunopathogenesis of endophthalmitis, and determine if cytokine profiles could serve as biomarkers of disease severity in infectious endophthalmitis.

Materials And Methods: Vitreous samples of 46 patients clinically diagnosed as endophthalmitis (of which 25 were culture positive) and 20 non-infectious controls from patients with Retinal Detachment (RD) or diabetic retinopathy were included in the study. The cytokine and chemokine expression patterns of 40 immune mediators including 6 antiinflammatory cytokines, 15 proinflammatory cytokines, 9 Growth factors and 10 proinflammatory chemokines in the vitreous were were analyzed by multiplex cytokine immunoassay. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205292PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175518PMC
March 2019
21 Reads
3.230 Impact Factor

Antibiotic resistance profile in eye infections in a reference centre in Floridablanca, Colombia.

Arch Soc Esp Oftalmol 2019 Jan 27;94(1):4-11. Epub 2018 Sep 27.

Centro Oftalmológico Virgilio Galvis, Floridablanca, Colombia.

Background And Objective: In view of the increasing bacterial resistance to antibiotics, it is necessary to determine it locally in order to serve as a guide in clinical management. The purpose of this study was to characterise the pattern of antibiotic sensitivity in cases of eye infections in a third level ophthalmological institution in Floridablanca (Colombia).

Materials And Methods: An observational cross-sectional study in which an analysis was made of the culture and antibiogram reports of specimens taken from cases of conjunctivitis, infectious keratitis, and endophthalmitis between January 2013 and June 2016. Read More

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http://dx.doi.org/10.1016/j.oftal.2018.07.003DOI Listing
January 2019
2 Reads

Endogenous bacterial endophthalmitis and subretinal abscess complicating diabetic ketoacidosis.

BMJ Case Rep 2018 Sep 18;2018. Epub 2018 Sep 18.

Ophthalmology Department, King's College Hospital NHS Foundation Trust, London, UK.

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http://dx.doi.org/10.1136/bcr-2018-227025DOI Listing
September 2018
5 Reads

Successful treatment of endogenous endophthalmitis with extensive subretinal abscess: a case report.

BMC Ophthalmol 2018 Sep 5;18(1):238. Epub 2018 Sep 5.

Departments of Gastroenterology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China.

Background: Endogenous endophthalmitis could lead to a devastating outcome without a prompt and appropriate management. We report a case of advanced endogenous Klebsiella pneumoniae endophthalmitis with extensive subretinal abscess that was successfully treated with a vitrectomy.

Case Presentation: A systemically well 61-year-old man complained of ocular pain and visual decrease in his right eye for eighteen days. Read More

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http://dx.doi.org/10.1186/s12886-018-0908-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125994PMC
September 2018
18 Reads

Disseminated Nocardiosis with subretinal abscess in a patient with nephrotic syndrome-a case report.

BMC Ophthalmol 2018 Sep 3;18(1):234. Epub 2018 Sep 3.

Departments of Gastroenterology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China.

Background: Nocardia infection is uncommon in clinical practice, with most cases occuring as the result of opportunistic infection in immunocompromsed patients. Here, we report a case of disseminated nocardiosis with subretinal abscess in a patient with nephrotic syndrome, and whom is receiving immunosuppressive therapy.

Case Presentation: A 58-year-old male presented with decreased vision in his left eye, without redness or floaters, which had persisted for three days. Read More

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http://dx.doi.org/10.1186/s12886-018-0883-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122714PMC
September 2018
4 Reads

Noninfectious Inflammatory Response following Intravitreal Bevacizumab Injections: Description of a Cluster of Cases in Two Centers and a Review of the Literature.

Ophthalmologica 2018 31;240(3):163-166. Epub 2018 Aug 31.

Department of Ophthalmology, Tel-Aviv Medical Center, affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

Purpose: To report a cluster of high incidence of noninfectious inflammatory reaction shortly after bevacizumab injection.

Methods: Data were collected from medical records of consecutive patients who underwent bevacizumab injections and presented with acute uveitis within 1-4 days.

Results: All 7 patients were injected intravitreally with bevacizumab from different batches and presented with visual deterioration. Read More

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http://dx.doi.org/10.1159/000492681DOI Listing
October 2018
25 Reads

Identification and Visualization of a Distinct Microbiome in Ocular Surface Conjunctival Tissue.

Invest Ophthalmol Vis Sci 2018 08;59(10):4268-4276

School of Biological, Earth and Environmental Sciences, University of New South Wales, Sydney, Australia.

Purpose: Knowledge of whether microorganisms reside in protected niches of the conjunctiva is potentially significant in terms of minimizing risks of contact lens inflammation/infection and endophthalmitis. We define if and how microbial communities from limbal and forniceal conjunctival tissue differ from those on the conjunctival surface.

Methods: Human limbal and forniceal conjunctival tissue was obtained from 23 patients undergoing pterygium surgery and analyzed with data from a recent study of conjunctival surface swabs (n = 45). Read More

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http://dx.doi.org/10.1167/iovs.18-24651DOI Listing
August 2018
19 Reads

In vitro synergistic effect of baicalin with azithromycin against Staphylococcus saprophyticus isolated from francolins with ophthalmia.

Poult Sci 2019 Jan;98(1):373-380

Institute of Traditional Chinese Veterinary Medicine, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, PR China.

Francolins ophthalmia is often caused by resistant conditional pathogenic bacteria. Conditional pathogenic Staphylococcus saprophyticus is a potential reservoir of macrolides antibiotics resistance gene. Baicalin has been reported as a potential agent to synergistically inhibit the replication of Staphylococcus. Read More

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http://dx.doi.org/10.3382/ps/pey356DOI Listing
January 2019
4 Reads

Outcomes of combined keratoplasty and pars plana vitrectomy for endophthalmitis with compromised corneal clarity.

Clin Exp Ophthalmol 2019 Jan 23;47(1):49-56. Epub 2018 Aug 23.

Dr. Shroff's Charity Eye Hospital, New Delhi, India.

Importance: Studies evaluating combined penetrating keratoplasty and pars plana vitrectomy for infectious aetiologies are limited.

Background: To evaluate the outcomes of combined penetrating keratoplasty and pars plana vitrectomy in patients with endophthalmitis and poor corneal clarity.

Design: Retrospective interventional case series conducted at a tertiary care eye hospital in North India. Read More

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http://dx.doi.org/10.1111/ceo.13370DOI Listing
January 2019
6 Reads

Epidemiology of uveitis (2013-2015) and changes in the patterns of uveitis (2004-2015) in the central Tokyo area: a retrospective study.

BMC Ophthalmol 2018 Aug 2;18(1):189. Epub 2018 Aug 2.

Department of Ophthalmology, University of Tokyo Graduate School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.

Background: The distribution of uveitis varies with genetic, ethnic, geographic, environmental, and lifestyle factors. Epidemiological information about the patterns of uveitis is useful when an ophthalmologist considers the diagnosis of uveitis. Therefore, it is important to identify the causes of uveitis over the years in different regions. Read More

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http://dx.doi.org/10.1186/s12886-018-0871-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090933PMC
August 2018
3 Reads

Community-acquired group B streptococcal meningitis in adults: 33 cases from prospective cohort studies.

J Infect 2019 Jan 29;78(1):54-57. Epub 2018 Jul 29.

Amsterdam UMC, University of Amsterdam, Department of Neurology, Amsterdam Neuroscience, Meibergdreef 9, The Netherlands. Electronic address:

Objectives: Streptococcus agalactiae (group B streptococcus, GBS) is an uncommon cause of bacterial meningitis in adults. We describe clinical characteristics, serotype distribution and outcome of adult GBS meningitis.

Patients And Methods: Patients aged 16 years or older with GBS cultured in cerebrospinal fluid included in two prospective nationwide cohort studies performed in the Netherlands between 1998-2002 and 2006-2017 were evaluated. Read More

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http://dx.doi.org/10.1016/j.jinf.2018.07.009DOI Listing
January 2019
5 Reads

A Case of Fulminant Endophthalmitis.

Clin Infect Dis 2017 08;65(3):527-528

Formerly at Kaiser Regional Reference Laboratory, North Hollywood, California.

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http://dx.doi.org/10.1093/cid/cix273DOI Listing
August 2017
2 Reads

Ocular culture-proven endogenous endophthalmitis: a 5-year retrospective study of the microorganism spectrum at a tertiary referral center in Turkey.

Int Ophthalmol 2018 Jul 26. Epub 2018 Jul 26.

Department of Ophthalmology, Marmara University School of Medicine, Fevzi Çakmak Mah. Muhsin Yazıcıoğlu Cad. No:10, Pendik/Istanbul, Turkey.

Purpose: The aim of this study was to review the clinical profile of endogenous endophthalmitis (EE), including predisposing systemic conditions, responsible microorganisms, clinical presentations, and outcomes.

Methods: We reviewed data from 21 eyes of 15 patients diagnosed with EE and compared their clinical characteristics over a 5-year period. All patients were ocular fluid cultures proven. Read More

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http://dx.doi.org/10.1007/s10792-018-0997-9DOI Listing
July 2018
1 Read

Bacterial endogenous endophthalmitis after colonoscopy.

Rev Esp Enferm Dig 2018 Sep;110(9):601

Aparato Digestivo, Hospital San Agustín, España.

We report a case with bacterial endogenous endophthalmitis caused by Streptococcus bovis, developed after colonoscopy, which had a poor outcome and resulted in evisceration. Bacterial endogenous endophthalmitis is a rare, but serious ocular disease that occurs when bacteria from a primary focus reach the eye. It requires a very early diagnosis. Read More

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http://dx.doi.org/10.17235/reed.2018.5658/2018DOI Listing
September 2018