Search Our Scientific Publications & Authors

IDCases 2019 29;15:e00499. Epub 2019 Jan 29.

Department of General Internal Medicine, Iizuka Hospital, Fukuoka, Japan.

Here, we present a 76-year-old diabetic man who was diagnosed as having endogenous endophthalmitis caused by that finally developed globe rupture, which is a rare endogenous endophthalmitis complication. This case highlight that endogenous endophthalmitis is an ophthalmological emergency with poor prognosis, thereby requiring prompt diagnosis and aggressive intervention. Read More

Clin Microbiol Infect 2019 Feb 13. Epub 2019 Feb 13.

Division of Infectious Diseases and Hospital Epidemiology, Departments of Medicine and Clinical Research, University Hospital of Basel and University of Basel, Basel, Switzerland.

Background: Adjunctive systemic antibiotic therapy for treatment of bacterial endophthalmitis is controversial but common practice due to the severity of the disease. In absence of guidance documents, several antibiotic regimens are being used without applying evidence-based prescribing, thus leading to inappropriate treatment of this serious eye condition.

Objectives: To summarize available data on intravitreal penetration of systemically administered antibiotics and to discuss their usefulness from a microbiological and pharmacological point of view. Read More

Middle East Afr J Ophthalmol 2018 Jul-Dec;25(3-4):163-166

Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Subretinal hypopyon is an uncommon entity which has been described in ocular infections and inflammations including endophthalmitis, acute retinal necrosis, and sympathetic ophthalmia. The authors report subretinal hypopyon in two cases of presumed tubercular uveitis which responded well to antitubercular therapy (ATT). The first case was a 47-year-old male with bilateral peripapillary chorioretinitis with a subretinal hypopyon. Read More

Graefes Arch Clin Exp Ophthalmol 2019 Feb 13. Epub 2019 Feb 13.

Department of Ophthalmology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211, Eonjuro, Gangnam-gu, Seoul, 135-720, South Korea.

Purpose: Infectious endophthalmitis (IE) is a severe complication that can lead to blindness even with treatment. However, the impact of antibiotic resistance and early vitrectomy on its prognosis has scarcely been documented. This study investigated the impact of antibiotic resistance of pathogen and early vitrectomy on the prognosis of IE. Read More

J Ophthalmol 2019 14;2019:1585830. Epub 2019 Jan 14.

Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan.

Purpose: Bleb-related endophthalmitis (BRE) after glaucoma surgery is an infection caused by bacteria in the avascular bleb gaining access into the eye. We report the clinical features and outcome of 10 consecutive eyes with severe BRE treated at our hospital.

Methods: Ten patients (10 eyes) with stage IIIb BRE after trabeculectomy diagnosed and treated at the Department of Ophthalmology, Tokyo Medical University, between April 2013 and May 2015, were studied. Read More

SAGE Open Med Case Rep 2019 30;7:2050313X19827403. Epub 2019 Jan 30.

Pedro Kourí Tropical Medicine Institute, La Habana, Cuba.

Bacterial endophthalmitis is the most severe form of vision-threatening ocular infection. is a primary respiratory pathogen that has been associated with several extrapulmonary manifestation, including ocular infection. In this work, we presented the microbiology diagnosis of an endophalmitis by using a novel A. Read More

Vet Ophthalmol 2019 Feb 4. Epub 2019 Feb 4.

Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, Georgia.

Objective: Identify dogs that required removal of an eye that had previously undergone a parotid duct transposition (PDT) and secondly to characterize demographics, surgical technique, and outcomes associated with it.

Procedure: An online survey was distributed to American College of Veterinary Ophthalmologists (ACVO) and Veterinary Ophthalmology (VOPH) listservs asking members to report the breed, reason for eye removal, time between surgeries, surgical technique, complications, and additional therapy instituted for dogs requiring removal of an eye subsequent to PDT surgery.

Results: Sixteen dogs fit the inclusion criteria. Read More

Ophthalmology 2019 Jan 31. Epub 2019 Jan 31.

Department of Ophthalmology, Oakland University William Beaumont School of Medicine, Associated Retinal Consultants, Royal Oak, MI.

Purpose: To report the structural and functional outcomes of the autologous neurosensory retinal transplant for closure of refractory large macular holes.

Design: Multicenter retrospective consecutive case series PARTICIPANTS: Forty-one eyes of 41 patients (27 female and 14 male) with a full thickness macular hole refractory to prior vitrectomy with internal limiting membrane peel and tamponade.

Methods: All patients underwent pars-plana vitrectomy, autologous neurosensory retinal transplant with either gas, silicone oil tamponade, or short-term Perfluoro-n-octane heavy-liquid tamponade. Read More

Sci Rep 2019 Jan 31;9(1):1071. Epub 2019 Jan 31.

Department of Ophthalmology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Endogenous K. pneumoniae endophthalmitis (EKE) has a higher incidence among East Asians, and the most common infectious source of EKE is pyogenic liver abscess (PLA). We investigate the risk factors for poor visual outcomes in patients with PLA-related EKE. Read More

Surv Ophthalmol 2019 Jan 28. Epub 2019 Jan 28.

Prism Eye Institute, University of Toronto, Ontario, Canada.

Toxic anterior segment syndrome (TASS) is a surgical complication characterized by a non-infectious anterior chamber inflammatory reaction having multiple etiologies. The clinical signs (prominent limbus to limbus corneal edema, anterior chamber inflammation) and symptoms (decreased visual acuity, discomfort) generally occur within the first 12-48 hours after intraocular surgery. Most patients achieve good clinical and visual outcomes when there is a prompt clinical diagnosis and adequate treatment. Read More

Sci Rep 2019 Jan 29;9(1):844. Epub 2019 Jan 29.

Jhaveri Microbiology Centre, Brien Holden Eye Research Centre, L. V. Prasad Eye Institute, Hyderabad, Telangana, India.

The proof-of-concept, study to investigate the presence of microorganisms in presumed infectious endophthalmitis using Next generation sequencing (NGS) was carried out in vitreous biopsies from 34 patients with endophthalmitis, and thirty patients undergoing surgery for non-infectious retinal disorders as controls. Following DNA extraction using the Qiagen mini kit and PCR amplification of the V3-V4 regions of the bacterial 16S rRNA and ITS 2 region of fungus, they samples were sequenced on an Illumina HiSeq 2500 Machine. Paired reads were curated, taxonomically labeled, and filtered. Read More

J Cataract Refract Surg 2019 Jan 25. Epub 2019 Jan 25.

School of Medical Sciences, University of Campinas, São Paulo, Brazil.

Purpose: To evaluate the safety and efficacy of intracameral (IC) 0.5% moxifloxacin in the prevention of post-cataract endophthalmitis.

Setting: University of Campinas, São Paulo, Brazil. Read More

J Ophthalmol 2018 27;2018:9250425. Epub 2018 Dec 27.

Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, 270 Xueyuan Road, Wenzhou, Zhejiang Province 325027, China.

Purpose: To report a new technique for sutureless intrascleral fixation of three-piece foldable intraocular lenses (IOLs) using 25-gauge trocars.

Methods: We performed this technique on patients with insufficient posterior capsule support. Seventeen eyes from 15 patients with aphakia, dislocated IOL, or subluxated crystalline lens undergoing posterior chamber sutureless implantation of an IOL were studied. Read More

BMC Ophthalmol 2019 Jan 25;19(1):32. Epub 2019 Jan 25.

Department of Ophthalmology, Xi'an No. 4 Hospital, Shaanxi Eye Hospital, Affiliated Guangren Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, 710004, Shaanxi Province, China.

Purpose: To assess the incidence of acute-onset endophthalmitis after separate bilateral cataract surgeries less than 5 days apart (SBCS5).

Methods: The medical records of all patients who underwent SBCS5 at a single medical center between October 10, 2012 and July 31, 2017 were retrospectively reviewed.

Results: The medical records for treatment of 5374 eyes of 2687 patients were examined. Read More

Retina 2019 Jan 23. Epub 2019 Jan 23.

Srimati Kanuri Santhamma Centre for Vitreo-Retinal Diseases, L V Prasad Eye Institute, Hyderabad, Telangana, India.

Purpose: To report the clinical presentation and management outcome of patients with endophthalmitis caused by Enterococcus species and to report the susceptibility profile of the isolates.

Methods: Twenty-nine cases with culture-proven Enterococcus endophthalmitis from January 2005 to May 2018 underwent vitrectomy/vitreous biopsy, intravitreal antibiotic with or without additional procedures. The undiluted vitreous was subjected to microbiologic evaluation. Read More

Eur J Clin Microbiol Infect Dis 2019 Jan 24. Epub 2019 Jan 24.

Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.

Local anesthetics (LAs) are medications which can provide analgesia in distinct body regions through the blockade of voltage-gated sodium channels. Besides pain management, the supplemental role of LAs as antimicrobial agents has been documented in several studies. Different databases including PubMed, Scopus, and Web of Science with the name of different local anesthetics and related names for antimicrobial keywords were searched without time limitation. Read More

Infect Disord Drug Targets 2019 Jan 23. Epub 2019 Jan 23.

Department of Microbiology, Government Medical College and Hospital, Sector 32, Chandigarh. India.

Acinetobacter species are widely distributed in soil, water and hospital environment. In addition to A. calcoaceticus-baumannii complex, the clinically most relevant species, there are other genomospecies which are less frequently identified, mostly due to lack of accurate methods for routine identification. Read More

Asia Pac J Ophthalmol (Phila) 2018 Jan 22. Epub 2018 Jan 22.

Retina Unit, Sydney Eye Hospital, Sydney, NSW, Australia.

Purpose: To evaluate the efficacy and safety of early pars plana vitrectomy (PPV) for the treatment of acute infective endophthalmitis, and identify prognostic factors for better visual outcome.

Design: Retrospective cohort study.

Methods: Consecutive patients who underwent early PPV within 72 hours of presentation for the treatment of acute infective bacterial endophthalmitis and presented to a large tertiary referral center in New South Wales, Australia, between January 2009 and December 2013 were included. Read More

Retin Cases Brief Rep 2019 Jan 17. Epub 2019 Jan 17.

Massachusetts Eye Research and Surgery Institution (MERSI), Waltham, Massachusetts.

Purpose: To report a case of systemic and ocular toxoplasmosis in an immunocompetent patient, who developed myocarditis with resulting cardiogenic shock and multiple organ failure, followed by bilateral panuveitis masquerading as endogenous endophthalmitis.

Methods: Single case report with images.

Results: A 59-year-old man with a history of monoclonal gammopathy of undetermined significance and associated scleromyxedema but otherwise immunocompetent was admitted to the intensive care unit for cardiogenic shock and multiple organ failure due to presumed viral myocarditis. Read More

Am J Ophthalmol Case Rep 2019 Mar 8;13:127-130. Epub 2018 Dec 8.

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller, School of Medicine, Miami, FL, USA.

Purpose: To describe an immunosuppressed patient who developed acute-onset postoperative endophthalmitis caused by a moxifloxacin-resistant strain of after cataract surgery despite the use of intracameral moxifloxacin.

Observations: A 76-year old woman with a history of birdshot chorioretinopathy controlled on systemic immunosuppression underwent uneventful cataract surgery in her right eye. Compounded intracameral moxifloxacin 0. Read More

J Microbiol Immunol Infect 2019 Jan 6. Epub 2019 Jan 6.

Department of Ophthalmology, Taipei Medical University Hospital, Taipei, Taiwan; Department of Ophthalmology, School of Medicine, College of Medicine, Taipei Medical University, Taiwan. Electronic address:

Purpose: Postoperative endophthalmitis caused by nontuberculous mycobacterium is a rare but devastating complication after intraocular surgery. However, optimal treatment strategies remain undetermined in view of its rarity.

Methods: We investigated the cases of culture-proven postoperative Mycobacteroides abscessus subsp. Read More

J Control Release 2019 Feb 17;296:68-80. Epub 2019 Jan 17.

Department of Ophthalmology, The Johns Hopkins University School of Medicine, 400 North Broadway, Baltimore, MD 21231, USA; Center for Nanomedicine, Wilmer Eye Institute, The Johns Hopkins University School of Medicine, 400 North Broadway, Baltimore, MD 21231, USA; Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, USA; Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, MD 21231, USA; Departments of Oncology, Neurosurgery, and Pharmacology & Molecular Sciences, The Johns Hopkins University, Baltimore, MD 21231, USA. Electronic address:

Noninfectious uveitis is a potentially blinding ocular condition that often requires treatment with corticosteroids to prevent inflammation-related ocular complications. Severe forms of uveitis such as panuveitis that affects the whole eye often require a combination of topical and either regional or systemic corticosteroid. Regional corticosteroids are currently delivered inside the eye by intravitreal injection (e. Read More

Graefes Arch Clin Exp Ophthalmol 2019 Jan 17. Epub 2019 Jan 17.

Department of Ophthalmology, Lund University, BMC D10, 22184, Lund, Sweden.

Purpose: To investigate the inflammatory response of current and future potential vitreous substitutes in an experimental in vivo vitrectomy model.

Methods: Twenty-five gauge pars plana vitrectomy was performed in the right eye of 60 pigmented rabbits, with subsequent injection of 0.5-1. Read More

Exp Ther Med 2019 Jan 20;17(1):869-873. Epub 2018 Nov 20.

Department of Ophthalmology, The General Hospital of Shenyang Military Area Command, Shenyang, Liaoning 110840, P.R. China.

The aim of the present study was to investigate the post-operative outcomes associated with Boston type 1 keratoprosthesis (Kpro-1) implantation in the treatment of patients with corneal blindness in Northeast China. Clinical data of patients who had undergone Kpro-1 implantation between July 2010 and November 2014 were retrospectively collected. The visual performance, implant retention and post-surgical complications were recorded for each patient. Read More

BMC Ophthalmol 2019 Jan 16;19(1):20. Epub 2019 Jan 16.

Eye Hospital, Wenzhou Medical University, 270 Xueyuan Road, Wenzhou, 325027, Zhejiang, China.

Background: The complete disassembly of nuclear is the most challenging step in hard cataract surgery through microincision. The classic phaco chop technique often does not succeed, resulting in incomplete nuclear segmentation. The authors describe a technique to improve the efficacy and safety of the initial chopping. Read More

Ophthalmology 2019 Jan 12. Epub 2019 Jan 12.

Department of Ophthalmology, Queen's University, Kingston, Canada; Department of Ophthalmology, Kingston Health Sciences Centre, Hotel Dieu Hospital Site, Kingston, Canada.

Purpose: Tamsulosin is associated with intraoperative floppy iris syndrome (IFIS), an important risk factor for complications during cataract surgery. Significant efforts have been made to increase awareness of the risks associated with tamsulosin, and educational initiatives have fostered the uptake of technical adjustments to decrease adverse event rates among tamsulosin-exposed patients. However, the effectiveness of these efforts at the population level has not been studied. Read More

J Ophthalmol 2018 16;2018:5149154. Epub 2018 Dec 16.

Department of Ophthalmology, United Christian Hospital, Kowloon, Hong Kong.

Purpose: To compare the surgical outcome of combined phacoemulsification and endoscopic cyclophotocoagulation (phacoECP) versus combined phacoemulsification and mitomycin C-augmented trabeculectomy (phacoTbx) in patients with coexisting glaucoma and visually significant cataract.

Methods: A retrospective review of 89 eyes of 89 patients who received phacoECP (=49) and phacoTbx (=40) was carried out at a tertiary eye center in Hong Kong. The minimum follow-up period was 6 months. Read More

Ophthalmic Surg Lasers Imaging Retina 2019 Jan;50(1):53-55

A woman with a past medical history of radiation and chemotherapy for multiple malignancies presented with bilateral, multifocal, elevated chorioretinal lesions associated with vitritis. The differential diagnosis included endogenous endophthalmitis and metastatic disease. Her extensive medical history and ill appearance at presentation in concert with vitritis and subretinal lesions was concerning for endogenous endophthalmitis. Read More

Ophthalmic Surg Lasers Imaging Retina 2019 Jan;50(1):33-38

Background And Objective: To report on the microbiology, management, and visual outcomes of intravitreal injection (IVI)-associated, culture-proven endophthalmitis.

Patients And Methods: All patients seen at a tertiary referral center with culture-proven endophthalmitis associated with an IVI between June 2007 and July 2017 were included in this retrospective analysis.

Results: Thirty-five patients with culture-positive endophthalmitis following IVI were identified. Read More

Br J Ophthalmol 2019 Jan 12. Epub 2019 Jan 12.

Academic Unit of Ophthalmology, Birmingham and Midland Eye Centre, City Hospital, Birmingham, UK.

Background/aim: Historic data suggest that open globe injuries should be repaired within 12-24 hours to reduce the risk of endophthalmitis. However, endophthalmitis is uncommon when systemic antibiotic prophylaxis is given. It is not clear whether delayed primary repair impacts visual outcomes in other ways or what is the optimum time to repair. Read More

Case Rep Ophthalmol 2018 Sep-Dec;9(3):484-486. Epub 2018 Dec 4.

Special Eye Hospital "Svjetlost,", Zagreb, Croatia.

is a human blood parasite that belongs to the genus . We would like to present a case of late endophthalmitis in one eye of a patient that underwent simultaneous bilateral grade 3 cataract surgery. Read More

J Mycol Med 2019 Jan 7. Epub 2019 Jan 7.

Department of Medical Microbiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Hormographiella aspergillata, a basidiomycete is a rare cause of human infection. We report a case of 70-year-old female with corneal ulcer and endophthalmitis caused by this agent. The patient had an intraocular implantation of lens following a cataract surgery. Read More

Int J Pharm 2019 Mar 7;558:43-52. Epub 2019 Jan 7.

Centro de Química Estrutural, Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal; Centro de Investigação Interdisciplinar Egas Moniz, Instituto Universitário Egas Moniz, Quinta da Granja, Monte de Caparica, 2829-511 Caparica, Portugal. Electronic address:

Cataract is highly prevalent among old population worldwide and replacement of the opacified crystalline lens by an intraocular lens (IOL) is the safest and the most effective treatment. Although not very frequently (0.02-0. Read More

Case Rep Ophthalmol Med 2018 2;2018:8306163. Epub 2018 Dec 2.

Department of Ophthalmology, Drexel University College of Medicine, Philadelphia, PA, USA.

Diagnosing culture-proven endophthalmitis is complicated by the insufficient yield of intraocular samples and the variety of etiologies which mimic true endophthalmitis. In cases of impending vision loss where vitreous biopsy cannot provide a definitive diagnosis, transvitreal retinochoroidal biopsy can be an effective next step. Our case is a 48-year-old male with B-cell acute lymphoblastic leukemia that presented with counting fingers vision, redness, and tearing of the left eye. Read More

Intern Med 2019 Jan 10. Epub 2019 Jan 10.

Division of Cardiovascular Medicine, Department of Internal Medicine, Jichi Medical University School of Medicine, Japan.

A 68-year-old Japanese man was admitted to our hospital with right eye pain, a sudden worsening of his eyesight, and a fever. He was diagnosed with endogenous bacterial endophthalmitis due to infectious endocarditis (IE) of Group B Streptococcus (GBS) on the day of admission. He recovered systemically, but his right eye became phthisical only with the administration of antibiotics. Read More

J Clin Exp Ophthalmol 2018 8;9(5). Epub 2018 Oct 8.

Department of Biomedical Engineering and Ophthalmology, University of Michigan, United States of America.

Objective: We propose a novel attachment method for retinal tissue that utilizes silicone modified with bioactive molecules.

Design: This is an experimental study divided into an section performed in cadaveric pig eyes and an section performed in rabbits.

Subjects: During experiments 36 cadaveric pig eyes were used. Read More

BMJ Case Rep 2018 12 31;11(1). Epub 2018 Dec 31.

J Res Med Sci 2018 28;23:98. Epub 2018 Nov 28.

Department of Biostatistics and Epidemiology, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Although posttraumatic endophthalmitis is an uncommon condition, it causes severe complications, so medical and pharmacological interventions for prevention of endophthalmitis after trauma are a major concern. The aim of this study was to evaluate the efficacy and clinical outcome of oral ciprofloxacin versus intravenous cefazolin/gentamicin for the prevention of endophthalmitis after penetrating ocular trauma.

Materials And Methods: This was a retrospective, descriptive single-center study, including all cases of penetrating ocular trauma seen in the Feiz Hospital, a Tertiary Referral Eye Hospital in Isfahan, Iran, between 2011 and 2017. Read More

Br J Hosp Med (Lond) 2019 Jan;80(1):C8-C11

Consultant Ophthalmologist, Clinical Director of Ophthalmology, Royal Free London NHS Foundation Trust, London.

Case Rep Ophthalmol Med 2018 18;2018:4614802. Epub 2018 Nov 18.

Ophthalmology Clinic, Medical Retina & Vitreoretinal Surgery Department, Venizeleio Hospital of Crete, Knossos Avenue 44, Heraklion of Crete, Greece.

We present a case of acute endophthalmitis after intravitreal dexamethasone implant injection and discuss the management of this rare and challenging case in which the implant could not be removed. A 50-year-old woman with a history of branch retinal vein occlusion in the right eye was treated with intravitreal dexamethasone implant injection for macular oedema. Four days after injection, the patient was admitted to the department with acute pain, decreased vision, and redness. Read More

PLoS One 2018 21;13(12):e0209849. Epub 2018 Dec 21.

Department of Pathology, University of Mississippi Medical Center, Jackson, Mississippi, United States of America.

The viridans group streptococci comprise multiple species and have gained more recognition in recent years as common etiologic agents of bacterial endophthalmitis. The purpose of this study was to identify the species of human endophthalmitis isolates of viridans streptococci and to characterize their potential virulence attributes. The species of 22 endophthalmitis strains of viridans streptococci were identified by Matrix Assisted Laser Desorption Ionization Time-of-Flight. Read More

BMJ Case Rep 2018 11 28;11(1). Epub 2018 Nov 28.

Department of Ophthalmology, Royal Bolton Hospital NHS Foundation Trust, Bolton, UK.

A middle-aged man presented to emergency services with central vision loss in the setting of flu-like illness with fever. A striking subfoveal abscess was observed in the right fundus. Focal acute chorioretinal inflammation was noted in the asymptomatic fellow eye. Read More

BMJ Case Rep 2018 Nov 28;11(1). Epub 2018 Nov 28.

Section of Infectious Diseases, Department of Medicine, College of Medicine & Philippine General Hospital, University of the Philippines Manila, Manila, Philippines.

A 48-year-old man presented with a non-healing wound on his left foot after stepping on a nail. He self-medicated with amoxicillin, but the wound progressed prompting consult. On examination, his left foot was diffusely swollen with surrounding erythema, areas of gangrene, foul-smelling purulent discharge and subcutaneous emphysema. Read More

Br J Ophthalmol 2018 Dec 18. Epub 2018 Dec 18.

Corneal Service, Moorfields Eye Hospital NHS Foundation Trust, London, UK

Purpose: To compare the incidence of fungal infection after endothelial keratoplasty (EK) when donor tissue had been stored in hypothermic medium or organ culture.

Methods: We describe the clinical features of 10 cases of fungal infection (keratitis or endophthalmitis) following EK identified at three European centres. Case definition was the culture of fungus or a positive PCR from the host cornea or anterior chamber after EK. Read More

Am J Ophthalmol 2018 Dec 15. Epub 2018 Dec 15.

Hyderabad, India.

BMC Infect Dis 2018 Dec 18;18(1):671. Epub 2018 Dec 18.

Department of Ophthalmology, Ningbo Eye Hospital, 855 Minan Road, Ningbo, 315040, China.

Background: This study reports a case of Unilateral Endogenous Fungal Endophthalmitis After Esophageal Cancer Surgery.

Case Presentation: One patient presented with a month-long loss of vision in his left eye, he had surgery for esophageal cancer 2 months earlier. The patient underwent cataract surgery (by phacoemulsification) in the left eye combined with 25-gauge vitrectomy and silicone oil tamponade. Read More

BMC Infect Dis 2018 Dec 17;18(1):669. Epub 2018 Dec 17.

Department of Respiratory Diseases, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.

Background: Endogenous endophthalmitis caused by hypervirulent Klebsiella pneumoniae (HVKP) is an emerging infectious disease commonly with a devastating visual outcome. Most HVKP strains display a wild-type susceptibility profile to antibiotics. However, reports of antimicrobial-resistant HVKP have increased over time, which poses a serious therapeutic dilemma. Read More

Enferm Infecc Microbiol Clin 2018 Dec 12. Epub 2018 Dec 12.

Unidad de Enfermedades Infecciosas, Hospital Universitario 12 de Octubre, Instituto de Investigación Hospital 12 de Octubre (imas12), Madrid, España.

Am J Ophthalmol 2018 Dec 12. Epub 2018 Dec 12.

Mid Atlantic Retina, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA. Electronic address:

Purpose: To compare the rates of infectious endophthalmitis following intravitreal injection of ranibizumab using prefilled syringes vs. conventional preparation.

Design: Multicenter, retrospective, cohort study METHODS: All eyes receiving intravitreal injection of 0. Read More

Am J Ophthalmol 2018 Dec 10. Epub 2018 Dec 10.

Austin, Texas, USA.