10,116 results match your criteria Endophthalmitis


Unusual presentation of Retinoblastoma.

Eur J Ophthalmol 2020 Jul 2:1120672120939388. Epub 2020 Jul 2.

Department of Radiodiagnosis, Government Medical College Hospital, Chandigarh, India.

Most cases of retinoblastoma are diagnosed before the age of 5 years. The cases in older age groups can have variable presentations leading to misdiagnosis and management challenges. We report a case of retinoblastoma in an 8-year-old female who was primarily referred as a case of sympathetic ophthalmia due to a co-incidental misleading history of penetrating eye injury to other eye 3 weeks prior. Read More

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http://dx.doi.org/10.1177/1120672120939388DOI Listing

The Role of Systemic Antimicrobials in the Treatment of Endophthalmitis: A Review and an International Perspective.

Ophthalmol Ther 2020 Jul 1. Epub 2020 Jul 1.

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.

Background: The optimal management of patients with endophthalmitis is challenging and includes both intravitreal and, in some cases, systemic antimicrobials. Systemic antimicrobials may be administered either intravenously or orally. In this article we review systemic antimicrobial options currently available for the treatment of types of endophthalmitis and the role of systemic antimicrobials (antibiotics and antifungals) in these treatments. Read More

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http://dx.doi.org/10.1007/s40123-020-00270-wDOI Listing

Clinical Etiologies, Microbial Spectrum, Antibiotic Susceptibilities, and Visual Acuity Outcomes of Acute Endophthalmitis.

J Ocul Pharmacol Ther 2020 Jun 29. Epub 2020 Jun 29.

Department of Ophthalmology and Visual Science, Yale School of Medicine, New Haven, Connecticut, USA.

The purpose of this study was to report the clinical etiologies, microbial spectrum, antibiotic resistance, and visual acuity (VA) outcomes associated with acute endophthalmitis. A retrospective chart review of patients with International Classification of Diseases (ICD)-9 and ICD-10 codes for endophthalmitis over a 6-year period (2011-2016) at a tertiary referral center was performed. The clinical records were reviewed to evaluate clinical etiologies, microbial spectrum, antibiotic susceptibilities and resistance, and visual outcomes. Read More

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http://dx.doi.org/10.1089/jop.2018.0074DOI Listing

Clinical analysis and predictive factors associated with improved visual acuity of infectious endophthalmitis.

BMC Ophthalmol 2020 Jun 29;20(1):256. Epub 2020 Jun 29.

Department of Ophthalmfology, Tianjin Medical University General Hospital, No. 154, Anshan Road, Tianjin, 300052, China.

Background: To describe the clinical characteristics and analyze the predictive factors associated with improved visual acuity of 359 patients with infectious endophthalmitis.

Methods: This study retrospectively analyzed 359 eyes of 359 patients with infectious endophthalmitis from January 2014 to December 2018. The findings summarized some epidemiological characteristics of these patients, including age, sex, occupation, patient visit time, etiology, causative organisms, therapy, and best-corrected visual acuity. Read More

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http://dx.doi.org/10.1186/s12886-020-01517-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325235PMC

Endophthalmitis After Cataract Surgery: Changes in Management Based on Microbiologic Cultures.

Ophthalmol Retina 2020 Jun 26. Epub 2020 Jun 26.

Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, PA. Electronic address:

Objective: To assess the utility of microbiologic culture data for the management of endophthalmitis following cataract surgery.

Design: Retrospective, single-center, cohort study PARTICIPANTS: All patients treated for endophthalmitis following cataract surgery between 1/1/2014 and 12/31/2017 at a single institution.

Methods: Endophthalmitis cases were determined from billing records and confirmed with chart review. Read More

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http://dx.doi.org/10.1016/j.oret.2020.06.028DOI Listing

Intravitreal piperacillin-tazobactam in endophthalmitis caused by ne-filled eye: A case report.

Indian J Ophthalmol 2020 Jul;68(7):1471-1473

Shri Bhagwan Mahavir Vitreoretinal Services, Medical Research Foundation, Chennai, Tamil Nadu, India.

A 28-year-old female came to us one month after retinal detachment surgery with a sudden painless drop in vision. The condition gradually worsened with ongoing treatment so she was taken up for lensectomy with silicone oil removal and intravitreal antibiotics and steroids. The microbiological analysis of silicone oil revealed Mycobacterium complex and gene sequencing isolated Mycobacterium abscessus, which showed antibiotic sensitivity to only piperacillin-tazobactam. Read More

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http://dx.doi.org/10.4103/ijo.IJO_1886_19DOI Listing

Meningoencephalitis due to endogenous endophthalmitis by in a diabetic patient.

Indian J Ophthalmol 2020 Jul;68(7):1456

Hospital Universitario Virgen de la Victoria, Radiology Department, Málaga, Spain.

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http://dx.doi.org/10.4103/ijo.IJO_2016_19DOI Listing

Post-cataract surgery cluster endophthalmitis due to multidrug-resistant : A retrospective cohort study of six clusters.

Indian J Ophthalmol 2020 Jul;68(7):1424-1431

Consultant, Cornea and Anterior Segment Services, MGM Eye Institute, Raipur, Chhattisgarh, India.

Purpose: To analyze clinical presentations, antibiotic susceptibility, and visual outcomes in six clusters of post cataract surgery endophthalmitis caused due to multidrug-resistant Pseudomonas aeruginosa (MDR-PA). This was a hospital-based retrospective cohort study.

Methods: Our study comprised sixty-two patients from six nonconsecutive clusters of post cataract surgery endophthalmitis caused by MDR-PA referred to our tertiary eye care institute. Read More

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http://dx.doi.org/10.4103/ijo.IJO_1612_19DOI Listing

Management of cluster endophthalmitis does not stop at clinical care.

Authors:
Taraprasad Das

Indian J Ophthalmol 2020 Jul;68(7):1249-1251

Srimati Kanuri Santamma Centre for Vitreoretinal Diseases, L V Prasad Eye Institute, Kallam Anji Reddy Campus, Hyderabad, Telangana, India.

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http://dx.doi.org/10.4103/ijo.IJO_502_20DOI Listing

Favourable outcome in paediatric endogenous endophthalmitis secondary to following pars plana vitrectomy.

BMJ Case Rep 2020 Jun 24;13(6). Epub 2020 Jun 24.

Ophthalmology Department, Manchester Royal Eye Hospital, Manchester, UK

Paediatric endogenous endophthalmitis is an uncommon but potentially devastating intraocular infection which should not be missed. Often cases present to the accident and emergency department. Accurate and prompt assessment is key in saving sight and life. Read More

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http://dx.doi.org/10.1136/bcr-2019-233133DOI Listing

Peri-Operative Intracameral Antibiotics: The Perfect Storm?

J Ocul Pharmacol Ther 2020 Jun 22. Epub 2020 Jun 22.

Department of Ophthalmology & Visual Sciences, University of California, Davis, California, USA.

In our University journal club we discussed a large, retrospective study of cataract surgery endophthalmitis rates before and after instituting the use of an intracameral fluoroquinolone antibiotic. We identified several factors involved in the use of off-label, compounded moxifloxacin in intraocular surgery. The introduction of phacoemulsification for cataract surgery led to the potential for smaller incisions. Read More

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http://dx.doi.org/10.1089/jop.2020.0034DOI Listing

Management and Visual Outcomes of Acute Bacterial Endophthalmitis Following Intravitreal Injection of Contaminated Bevacizumab in a Single Day.

Ophthalmic Surg Lasers Imaging Retina 2020 Jun;51(6):346-352

Background And Objective: Bevacizumab requires compounding for off-label intravitreal injection, thus creating a risk of possible contamination during preparation.

Patients And Methods: This retrospective, consecutive case series from a single site included patients who developed culture-proven acute endophthalmitis after intravitreal injection with contaminated bevacizumab. All patients suspected of endophthalmitis had vitreous biopsy and microbial cultures prior to initiation of treatment and were managed with immediate tap and injection of antibiotics followed early by pars plana vitrectomy. Read More

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http://dx.doi.org/10.3928/23258160-20200603-05DOI Listing

Ciprofloxacin Loaded Nanostructured Lipid Carriers Incorporated into In-Situ Gels to Improve Management of Bacterial Endophthalmitis.

Pharmaceutics 2020 Jun 19;12(6). Epub 2020 Jun 19.

Department of Pharmaceutics and Drug Delivery, School of Pharmacy, University of Mississippi, Oxford, MS 38677, USA.

Bacterial endophthalmitis (BE) is a potentially sight-threatening inflammatory reaction of the intraocular fluids or tissues caused by bacteria. Ciprofloxacin (CIP) eye drops are prescribed as first-line therapy in BE. However, frequent administration is necessary due to precorneal loss and poor ocular bioavailability. Read More

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http://dx.doi.org/10.3390/pharmaceutics12060572DOI Listing

Postoperative complications in Medicare beneficiaries following endothelial keratoplasty (EK) surgery.

Am J Ophthalmol 2020 Jun 20. Epub 2020 Jun 20.

The Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD. Electronic address:

Purpose: To determine national-level incidence rates of major postoperative complications following EK procedures, and to stratify these rates based on EK indications over an 8-year period using Medicare claims data.

Design: Retrospective, cohort study METHODS: .

Setting: Population-based STUDY POPULATION: Medicare beneficiaries aged ≥65 years who underwent EK procedures MAIN OUTCOME MEASURE(S): 1) Occurrence of major postoperative complications (i. Read More

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http://dx.doi.org/10.1016/j.ajo.2020.05.033DOI Listing

Open globe injuries in children under 7 years referred to a tertiary center in Iran from 2006 to 2016.

Eye (Lond) 2020 Jun 22. Epub 2020 Jun 22.

Ocular Trauma and Emergency Department, Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Purpose: Open globe injuries are one of the most common causes of monocular blindness in many countries. The impact of this traumatic event on patients' quality of life and health is considerable. This study describes the characteristics of open globe injury in children younger than 7 years. Read More

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http://dx.doi.org/10.1038/s41433-020-1023-9DOI Listing

Twenty years of endophthalmitis: Incidence, aetiology and clinical outcome.

Acta Ophthalmol 2020 Jun 22. Epub 2020 Jun 22.

Department of Ophthalmology, Stavanger University Hospital, Stavanger, Norway.

Purpose: To review the incidence, aetiology and outcomes of endophthalmitis during a 20-year period in a Norwegian university hospital.

Methods: Single-centre retrospective review. Medical records of all patients admitted to Stavanger University Hospital with suspected endophthalmitis between January 1999 and December 2018 were reviewed. Read More

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http://dx.doi.org/10.1111/aos.14511DOI Listing

Predictive factors of enucleation after open globe injuries.

Graefes Arch Clin Exp Ophthalmol 2020 Jun 21. Epub 2020 Jun 21.

Rutgers New Jersey Medical School, Institute of Ophthalmology and Visual Science, Rutgers University, 90 Bergen Street, Newark, NJ, 07103, USA.

Background: Trauma is the leading cause of enucleations in the USA. Current information regarding open globe injuries (OGI) is based mainly on data from individual tertiary care centers across the country which might skew the findings towards the population served by these level-one trauma centers. The aim of this study is to evaluate the demographics, characteristics, and risk factors of traumatic enucleations in a large data sample. Read More

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http://dx.doi.org/10.1007/s00417-020-04794-6DOI Listing

Delayed-onset bleb-related endophthalmitis caused by Moraxella nonliquefaciens.

Arch Soc Esp Oftalmol 2020 Jun 17. Epub 2020 Jun 17.

Departamento de Oftalmología, Hospital Clínico Universitario de Valencia, Valencia, España; Facultad de Medicina, Universidad de Valencia, Valencia, España.

Bleb-related endophthalmitis is rare and appears months or years after surgery. The causative agents are usually streptococci or gram-negative bacteria. There are few cases in the literature of endophthalmitis caused by Moraxella nonliquefaciens, and most are delayed-onset associated with blebitis after glaucoma filtration surgery. Read More

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http://dx.doi.org/10.1016/j.oftal.2020.05.012DOI Listing

Fungal endocarditis in transplant recipients: a systematic review.

Mycoses 2020 Jun 18. Epub 2020 Jun 18.

Department of Internal Medicine & Infectious Diseases, University Hospital of Heraklion, Heraklion, Greece.

Background: Invasive fungal infections remain a major cause of morbidity and mortality in transplant recipients. Moreover, Fungal Infective Endocarditis (FIE) is a rare infection that carries a higher mortality than bacterial IE in normal host, while in transplant recipients may be even higher. The purpose of this study was to systemically review all published cases of FIE in solid organ and allogeneic bone marrow transplant recipients, describe the epidemiology, microbiology, clinical characteristics, treatment and outcomes of these infections, and to identify risk factors for mortality by FIE. Read More

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http://dx.doi.org/10.1111/myc.13132DOI Listing

Combined Endoscope assisted Procedures (CEaP) as a complete treatment for neovascular glaucoma.

PLoS One 2020 17;15(6):e0234798. Epub 2020 Jun 17.

Department of Ophthalmology, Taichung Veterans General Hospital, Taichung, Taiwan.

Purpose: To investigate the effect and complications of Combined Endoscope assisted Procedures (CEaP): endoscopic cyclophotocoagulation and pars plana ablation (ECP-plus), along with endoscopic panretinal photocoagulation (PRP).

Patients And Methods: The study design is a retrospective and noncomparative interventional case series from a tertiary referral center in Taiwan. Patients experiencing vessel growth at the iris and anterior chamber angle, along with an IOP > 21 mmHg were included. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0234798PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299373PMC

Endogenous endophthalmitis during pregnancy: Case report.

Arch Soc Esp Oftalmol 2020 Jun 15. Epub 2020 Jun 15.

Servicio de Retina y Vítreo, Instituto de la Retina del Bajío, Santiago de Querétaro, México.

Endogenous endophthalmitis is a disease that potentially threatens vision. It is produced by the haematogenous spread of microorganisms from a septic focus. It is a rare condition that is related to debilitating diseases, immunosuppression states, and invasive procedures. Read More

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http://dx.doi.org/10.1016/j.oftal.2020.05.009DOI Listing

A case report of fulminant endophthalmitis caused by Streptococcus dysgalactiae in a patient with traumatic corneal laceration.

BMC Ophthalmol 2020 Jun 18;20(1):238. Epub 2020 Jun 18.

Department of Cornea and Refractive Surgery, Kim's Eye Hospital, 136, Yeongshin-ro, Yeongdeungpo-gu, Seoul, South Korea.

Background: To report a case of enucleation caused by Streptococcus dysgalactiae endophthalmitis after traumatic corneal laceration.

Case Presentation: A 69-year-old man with history of retinal detachment treated with vitrectomy and subsequent cataract surgery presented with traumatic corneal laceration while cutting grass. Appropriate repair of corneal laceration and intravitreal antibiotics (vancomycin, ceftazidime) injection was performed. Read More

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http://dx.doi.org/10.1186/s12886-020-01511-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301497PMC

Pre-operative conjunctival flora in patients with local and/or systemic risk factors for post cataract surgery infection in Northern Italy.

Eur J Ophthalmol 2020 Jun 19:1120672120934991. Epub 2020 Jun 19.

University Eye Clinic, IRCCS, Policlinico San Matteo, Pavia, Italy.

Purpose: To investigate the pre-operative conjunctival flora in patients undergoing cataract surgery with major local and/or systemic risk factors for developing post-operative infection.

Methods: A total of 83 patients underwent bacterial culture and sensitivity testing of conjunctival swabs obtained from both eyes because of local risk factors at the pre-operative visit (i.e. Read More

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http://dx.doi.org/10.1177/1120672120934991DOI Listing

Intraoperative Cefuroxime Irrigation Prophylaxis for Acute-Onset Endophthalmitis After Phacoemulsification Surgery.

Infect Drug Resist 2020 18;13:1455-1463. Epub 2020 May 18.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Qingdao, People's Republic of China.

Purpose: Acute-onset postoperative endophthalmitis usually compromises the visual function and anatomical integrity of the eye. The aim of this study was to evaluate the efficacy of intraoperative cefuroxime use in irrigating solution on prevention of acute-onset endophthalmitis after phacoemulsification.

Methods: This retrospective, comparative, interventional cohort study included patients who underwent phacoemulsification between January 1, 2012, and December 31, 2019. Read More

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http://dx.doi.org/10.2147/IDR.S252674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244738PMC

Clinical Course and Characteristics of Eyes that Developed Recurrent Episodes of Endophthalmitis.

Ophthalmol Retina 2020 Jun 13. Epub 2020 Jun 13.

Associated Retinal Consultants P.C., William Beaumont Hospital, Royal Oak, MI, USA; Oakland University William Beaumont School of Medicine, Rochester, MI, USA. Electronic address:

Purpose: Infectious endophthalmitis is a devastating, yet rare complication following intraocular surgery, trauma, and systemic illness. Given its rare incidence, few patients would be expected to have more than one episode of infectious endophthalmitis in their lifetime. We reviewed our patients who were diagnosed with, and treated for, at least two separate episodes of endophthalmitis. Read More

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http://dx.doi.org/10.1016/j.oret.2020.06.011DOI Listing

A Novel Vitreous Culture Technique.

Retin Cases Brief Rep 2020 Jun 5. Epub 2020 Jun 5.

Colorado Retina Associates, PC, 8101 E Lowry Blvd, Suite 210, Denver, CO 80230.

Purpose: This is the first case series of a novel method of collecting and transporting a vitreous specimen after a vitreous tap and injection for infectious endophthalmitis.

Methods: Case series RESULTS:: Four consecutive cases of presumed infectious endophthalmitis underwent an in-office vitreous tap and antibiotic injection. The vitreous specimen was injected into the ESwab liquid-based collection and transport system for microbiology samples. Read More

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http://dx.doi.org/10.1097/ICB.0000000000001012DOI Listing

Coccidioidal Endophthalmitis: Excellent Recovery of Vision with Aggressive Use of Intravitreal Antifungals and Vitrectomy.

Retin Cases Brief Rep 2020 Jun 8. Epub 2020 Jun 8.

Retina Service, Department of Ophthalmology, University of California, San Francisco, San Francisco, California, USA.

Purpose: To report a case of Coccidioides immitis endophthalmitis with severe vision loss and a return to excellent vision following aggressive intervention.

Methods: Case report.

Results: A 41-year-old male with a history of solid organ transplantation who complained of floaters and decreased vision in the setting of disseminated Coccidioides infection was found to have presumed coccidioidal endophthalmitis with visual acuities (VA) of 20/20 in the right eye and 20/200 in the left eye. Read More

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http://dx.doi.org/10.1097/ICB.0000000000001022DOI Listing

Bilateral endophthalmitis following bilateral same-day anti-VEGF injections.

Acta Ophthalmol 2020 Jun 13. Epub 2020 Jun 13.

Department of Ophthalmology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

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http://dx.doi.org/10.1111/aos.14504DOI Listing

Endophthalmitis after strabismus surgery: incidence and outcome in relation to age, operated eye muscle, surgical technique, scleral perforation and immune state.

Acta Ophthalmol 2020 Jun 13. Epub 2020 Jun 13.

University Eye Clinic, Freiburg, Germany.

Purpose: Identify risk factors for endophthalmitis after strabismus surgery (EASS) and relate these to incidence and outcome.

Methods: Ophthalmologists, who had operated, diagnosed or treated EASS, completed a case record form with 71 questions in six domains: Preoperative, Surgery, Perforation, Postoperative, Outcome and Experts' opinion. To estimate the age-specific incidence per number of strabismus operations in the Netherlands during 1994-2013, the age distribution of Dutch cases was compared with the age-specific rates of strabismus surgery in the Dutch Registry of Strabismus Operations and with population data. Read More

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http://dx.doi.org/10.1111/aos.14446DOI Listing

Characteristics of paediatric patients hospitalised for eye trauma in 2007-2015 and factors related to their visual outcomes.

Eye (Lond) 2020 Jun 9. Epub 2020 Jun 9.

Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, 200031, China.

Objective: To analyse the epidemiological characteristics and clinical features of children under the age of 16 years with ocular trauma at the Eye and Ear, Nose and Throat Hospital of Fudan University (Shanghai, China) and to investigate the preventive measurements taken to avoid vision-threatening eye trauma.

Methods: The inpatient medical records of children <16 years old treated for ocular trauma between January 2007 and December 2015 were collected. The age, sex, type of trauma, cause of injury, complications and visual acuity on admission and discharge were analysed statistically. Read More

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http://dx.doi.org/10.1038/s41433-020-1002-1DOI Listing

CLINICAL UTILITY OF BETA-D-GLUCAN TESTING FOR ENDOGENOUS FUNGAL CHORIORETINITIS OR ENDOPHTHALMITIS.

Retina 2020 Jun 8. Epub 2020 Jun 8.

Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Philadelphia, Pennsylvania.

Purpose: To evaluate serum beta-D-glucan (BDG) as a biomarker for endogenous fungal eye infection.

Methods: Retrospective case-control study of 88 patients with a BDG test and eye examination at UPenn (2013-2018). Cases had endogenous fungal chorioretinitis or endophthalmitis diagnosed by eye examination and confirmed with positive culture; controls were without these fungal eye findings. Read More

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http://dx.doi.org/10.1097/IAE.0000000000002861DOI Listing

Clinical Review of Microbial Corneal Ulcers Resulting in Enucleation and Evisceration in a Tertiary Eye Care Center in Hungary.

J Ophthalmol 2020 18;2020:8283131. Epub 2020 May 18.

Department of Ophthalmology, Semmelweis University, Budapest, Hungary.

Purpose: To analyse the clinical and microbiological characteristics and preexisting ophthalmic and systemic conditions of infectious keratitis resulting in enucleation/evisceration in a large tertiary referral center in a developed country (Hungary) over a period of 12 years. . A retrospective review of enucleated/eviscerated eyes undergoing surgery between 2007 and 2018 at the Department of Ophthalmology of Semmelweis University, Budapest, Hungary, with infectious keratitis as the primary indication for enucleation or evisceration. Read More

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http://dx.doi.org/10.1155/2020/8283131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254073PMC

Toll-like receptors in acute post-cataract surgery endophthalmitis.

Int Ophthalmol 2020 Jun 7. Epub 2020 Jun 7.

Departments of Pathology, Government Medical College and Hospital, Chandigarh, India.

Objective: To evaluate the expression of toll-like receptor 2 (TLR2) and toll-like receptor 4 (TLR4) on CD14 + cells in vitreous and blood of post-cataract surgery acute endophthalmitis.

Design: This prospective case-control pilot study enrolled 16 patients of post-cataract surgery endophthalmitis. All the cases were subjected to 23 G pars plana vitrectomy (PPV). Read More

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http://dx.doi.org/10.1007/s10792-020-01457-7DOI Listing

Infectious Endophthalmitis in the Current Era.

Ophthalmol Retina 2020 06;4(6):553-554

Aurora, Colorado.

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http://dx.doi.org/10.1016/j.oret.2020.04.002DOI Listing

Baseline visual acuity and interdigitation zone as predictors in idiopathic epiretinal membranes: A retrospective cohort study.

Eur J Ophthalmol 2020 Jun 8:1120672120932094. Epub 2020 Jun 8.

Faculdade de Medicina Universidade do Porto, Alameda Prof. Hernâni Monteiro, Porto, Portugal.

Objective: Determine which functional and anatomical characteristics may be predictors of final visual acuity in patients with idiopathic ERM (iERM) submitted to pars plana vitrectomy (PPV) with ERM and internal and internal limiting membrane (ILM) peeling.

Design: Retrospective cohort study.

Subjects: Patients with iERM submitted to PPV between 2016 and 2017. Read More

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http://dx.doi.org/10.1177/1120672120932094DOI Listing

Endogenous Endophthalmitis successfully treated with Intravitreal Povidone-iodine injection: a case report.

BMC Ophthalmol 2020 Jun 5;20(1):217. Epub 2020 Jun 5.

Edogawa Hospital, Tokyo, Japan.

Background: The usefulness of povidone-iodine as an alternative to antimicrobial agents, for endophthalmitis, has recently been documented. We report a case of endogenous endophthalmitis successfully treated with intravitreal injection of povidone-iodine.

Case Presentation: An 88-year-old woman underwent small bowel bypass surgery for postoperative ileus following rectal cancer resection. Read More

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http://dx.doi.org/10.1186/s12886-020-01487-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275355PMC

Bacterial contamination of intravitreal needles by the ocular surface microbiome.

Ocul Surf 2020 Jun 1. Epub 2020 Jun 1.

School of Biological, Earth and Environmental Sciences, University of New South Wales, Sydney, Australia.

Purpose: The ocular surface microbiota are recognised as one of causative microorganisms in post-procedural endophthalmitis but in many cases the vitreous tap is culture negative. This study investigated bacterial contamination of intravitreal (IVT) needles using multiple approaches covering culturing, 16S rRNA gene sequencing, fluorescent in situ hybridisation (FISH) and scanning electron microscopy (SEM).

Methods: IVT needles were obtained immediately after injection from patients undergoing treatment for predominantly age-related macular degeneration. Read More

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http://dx.doi.org/10.1016/j.jtos.2020.05.010DOI Listing

A comparative study of post-operative endophthalmitis between immediate versus delayed management of eventful cataract extraction.

Pak J Med Sci 2020 May-Jun;36(4):689-692

Prof. Syed Fawad Rizvi, MCPS (Ophth), FCPS (Ophth). Layton Rahamatullah Benevolent Trust (LRBT), Free Base Eye Hospital, Korangi 2 ½, Karachi, Pakistan.

Objective: To compare the incidence of postoperative endophthalmitis after eventful cataract surgery i.e. posterior capsular rupture, in patients managed with anterior vitrectomy and intra ocular lens implantation intraoperatively to patients managed with anterior vitrectomy and intraocular lens implantation two weeks after the posterior capsule rupture. Read More

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http://dx.doi.org/10.12669/pjms.36.4.1911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260893PMC

Effectiveness and safety of ranibizumab 0.5 mg in treatment-naïve patients with diabetic macular edema: Results from the real-world global LUMINOUS study.

PLoS One 2020 3;15(6):e0233595. Epub 2020 Jun 3.

Department of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria.

Purpose: To assess the one-year effectiveness and safety of ranibizumab 0.5 mg in treatment- naïve patients with diabetic macular edema (DME) enrolled in the real-world LUMINOUS study.

Patients And Methods: A 5-year, prospective, observational, open-label, global study which recruited 30,138 patients across all approved indications. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0233595PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269267PMC

Preparation and evaluation of nanoliposomes containing vancomycin after intravitreal injection in albino rabbits.

Iran J Basic Med Sci 2020 Apr;23(4):551-555

Department of Pharmaceutical Control, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.

Objectives: The efficacy of nanoliposomal formulation of vancomycin against methicillin-resistant (MRSA) assessed.

Materials And Methods: Nanoliposomal formulations were prepared and characterized. The study was carried out on rabbits which received liquid culture medium containing MRSA under anesthesia. Read More

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http://dx.doi.org/10.22038/ijbms.2020.43447.10205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239418PMC
April 2020
0.604 Impact Factor

A survey exploring ophthalmologists' attitudes and beliefs in performing Immediately Sequential Bilateral Cataract Surgery in the United Kingdom.

BMC Ophthalmol 2020 Jun 2;20(1):210. Epub 2020 Jun 2.

Brighton and Sussex Medical School, Brighton, UK.

Background: The standard approach to treat cataracts is Delayed Sequential Bilateral Cataract Surgery (DSBCS), during which patients have a separate operation date for each eye. An alternative method of delivery is Immediately Sequential Bilateral Cataract Surgery (ISBCS). The aim of this project was to examine the attitudes and beliefs of UK ophthalmologists towards ISBCS, explore their reasons to either practise or not practise ISBCS and identify barriers hindering its implementation in the UK. Read More

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http://dx.doi.org/10.1186/s12886-020-01475-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265252PMC

The first case of fungal endogenous endophthalmitis caused by : Diagnostic and therapeutic challenge.

Eur J Ophthalmol 2020 Jun 3:1120672120932088. Epub 2020 Jun 3.

Hospital General Universitario de Valencia, Valencia, Spain.

Significance: Fungal endogenous endophthalmitis is an uncommon and potentially blinding infection. is a causative organism in immunocompromized although is virulent enough to afflict immunocompetents. Their propensity to affect macula usually results in a dismal prognosis; thus, improving visual outcome has always been challenging to clinicians. Read More

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http://dx.doi.org/10.1177/1120672120932088DOI Listing

Genotypic and Phenotypic Antibiotic Resistance in Staphylococcus Epidermidis Endophthalmitis.

Ophthalmic Surg Lasers Imaging Retina 2020 05;51(5):S13-S16

Background And Objective: To evaluate antibiotic resistance patterns in Staphylococcus epidermis endophthalmitis isolates, identify antibiotic resistance genes, and compare this to their phenotypic resistance.

Materials And Methods: Retrospective case series of S. epidermidis isolates from January 2012 to December 2017. Read More

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http://dx.doi.org/10.3928/23258160-20200108-02DOI Listing

Intravitreal aflibercept for management of choroidal neovascularization secondary to angioid streaks: The Italian EYLEA-STRIE study.

Eur J Ophthalmol 2020 Jun 2:1120672120928305. Epub 2020 Jun 2.

Universita Vita-Salute San Raffaele, Milano, Italy.

Purpose: To investigate the effect and the safety of intravitreal aflibercept in patients affected by choroidal neovascularization secondary to angioid streaks with a long-term follow-up.

Methods: Multicentre, open-label, phase IIb study (EYLEA-STRIE, EudraCT Number 2014-000986-30) involving four Italian centres (IRCCS Ospedale San Raffaele (Milano), Fondazione G.B. Read More

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http://dx.doi.org/10.1177/1120672120928305DOI Listing

Effect of intravitreal ceftazidime injection on endogenous klebsiella pneumoniae endophthalmitis, a single center case series.

Medicine (Baltimore) 2020 May;99(22):e20521

Department of Ophthalmology Sanggye Paik Hospital, Inje University of Korea, College of Medicine, Seoul, Republic of Korea.

To report long-term outcomes of intravitreal ceftazidime injection in patients with endogenous Klebsiella pneumoniae endophthalmitis (EKPE).This was a retrospective observational case study, including 7 eyes from 6 patients with EKPE. The medical records from January 2010 to December 2018 were reviewed. Read More

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http://dx.doi.org/10.1097/MD.0000000000020521DOI Listing

A novel, low-cost and practical illumination approach for bimanual vitrectomy.

North Clin Istanb 2020 11;7(3):275-279. Epub 2020 Feb 11.

Department of Ophthalmology, Istanbul Medeniyet University Faculty of Medicine, Istanbul, Turkey.

Objective: The present study aims to describe a novel, low-cost, transconjunctival sutureless bimanual vitrectomy illumination approach and evaluate its surgical outcome.

Methods: Thirty-six eyes of 36 patients who underwent pars plana vitrectomy with the above-mentioned technique were included in this study. Four trocars were placed in superotemporal, inferotemporal, inferonasal and superonasal quadrants. Read More

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http://dx.doi.org/10.14744/nci.2020.21704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251264PMC
February 2020

Traumatic intralenticular abscess-What is so different?

Indian J Radiol Imaging 2020 Jan-Mar;30(1):92-94. Epub 2020 Mar 30.

Consultant, Cornea and Refractive Services, Aravind Eye Hospital, Pondicherry, India.

Intralenticular abscess is a very rare entity that occurs after trauma, cataract surgeries, or as metastatic infection. It is important to pinpoint this sequestrated infection and to evacuate the abscess surgically to prevent chronic endophthalmitis. In this report, we describe a case of posttraumatic lenticular abscess highlighting the characteristic clinical features and their management. Read More

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http://dx.doi.org/10.4103/ijri.IJRI_369_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240887PMC

Total Filling of the Vitreous Cavity With a Cohesive Ophthalmic Viscosurgical Device to Support the Removal of the Intraocular Foreign Body.

Retina 2020 May 28. Epub 2020 May 28.

Department of Ophthalmology, Poznan University of Medical Sciences, Poznan, Poland.

Purpose: To evaluate the effectiveness of loading the vitreous cavity with a cohesive ophthalmic viscosurgical device in aiding the removal of the posterior segment intraocular foreign body (IOFB).

Methods: Seven consecutive patients underwent a small-gauge vitrectomy due to eye trauma with the IOFB between January 2019 and December 2019. The IOFB removal was initiated after total filling the vitreous cavity with the ophthalmic viscosurgical device (Eyefill C or Bio-Hyalur Plus) to facilitate maneuvering and slow the descent in cases of the unintendedly released IOFBs. Read More

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http://dx.doi.org/10.1097/IAE.0000000000002858DOI Listing

Endophthalmitis in Advanced Microbial Keratitis: Risk Factors and Examination Findings.

Cornea 2020 May 29. Epub 2020 May 29.

Department of Ophthalmology, University of Michigan Medical School, Ann Arbor, MI.

Purpose: To evaluate clinical and ultrasonographic findings associated with advanced microbial keratitis with concurrent endophthalmitis.

Methods: We performed a retrospective analytical study of patients with severe microbial keratitis who underwent ocular ultrasonography for possible endophthalmitis at our institution over a 5-year period. Ocular and medical history, ocular examination findings, microbiology results, and ultrasonographic features were collected. Read More

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http://dx.doi.org/10.1097/ICO.0000000000002349DOI Listing