6,440 results match your criteria Endometritis

Advances in the ultrasound diagnosis in equine reproductive medicine: new approaches.

Reprod Domest Anim 2022 Jun 24. Epub 2022 Jun 24.

Laboratory of Equine Reproduction and Equine Spermatology, Veterinary Teaching Hospital, University of Extremadura, Cáceres, Spain.

Ultrasound technology has led to new lines of research in equine reproduction, and it has helped to greatly improve clinical diagnosis and reproductive outcomes in equine practice. This review aims to discuss the potential clinical uses and new approaches of ultrasonography in equine reproduction. Doppler modalities are usually used to evaluate the vascularization of the follicles, corpus luteum (CL), and the uterus in the mare for diagnostic purposes. Read More

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The Expression and Bioinformatics Analysis of Circular RNAs in Endometritis Mouse Uterus Tissues.

Molecules 2022 Jun 8;27(12). Epub 2022 Jun 8.

Joint Laboratory of the Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.

Previous studies have shown that circular RNAs are directly or indirectly involved in the occurrence of various diseases by regulating gene expression. However, the acting mechanism of circular RNAs in endometritis remains unclear. In this study, we successfully established an endometritis model in mouse using ; endometrial integrity was destroyed, inflammatory cells infiltrated and the expression of IL-6, IL-1β, TNF-α was significantly up-regulated. Read More

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Antibiotic Prophylaxis to Prevent Obesity-Related Induction Complications in Nulliparae at Term (APPOINT): A Pilot Randomized Controlled Trial.

Am J Obstet Gynecol MFM 2022 Jun 18:100681. Epub 2022 Jun 18.

Department of Obstetrics and Gynecology, Section of Maternal-Fetal Medicine, University of Oklahoma College of Medicine, Oklahoma City, OK, USA.

Background: Obese women are at increased risk for complications during and after labor and delivery, including puerperal infection and cesarean delivery. Since labor induction has become increasingly common, it is crucial to find ways to decrease complication rates in this high-risk population.

Objective: To explore the effect of prophylactic antibiotics during labor induction of obese, nulliparous women on rates of cesarean delivery and puerperal infection, and to estimate the parameters needed to calculate the sample size for a larger, multicenter trial. Read More

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Dietary Tryptophan-Mediated Aryl Hydrocarbon Receptor Activation by the Gut Microbiota Alleviates Escherichia coli-Induced Endometritis in Mice.

Microbiol Spectr 2022 Jun 21:e0081122. Epub 2022 Jun 21.

Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Jilin Universitygrid.64924.3d, Changchun, Jilin Province, China.

Intestinal microbiota-mediated aryl hydrocarbon receptor (AhR) activation plays an important role in host-microbiota interactions and disease development. However, whether AhR activation mediates infection-induced inflammation in remote organs is not clear. The purpose of this study is to assess the effects and underlying mechanism of AhR activation and gut microbiota-mediated dietary tryptophan (Trp) metabolism on infection-induced inflammation using an Escherichia coli (E. Read More

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Serum Essential Trace Element Status in Women and the Risk of Endometrial Diseases: a Case-Control Study : Serum Essential Trace Element Status in Women and the Risk of Endometrial Diseases: a Case-Control Study.

Biol Trace Elem Res 2022 Jun 21. Epub 2022 Jun 21.

Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Anhui Medical University, No. 218 Jixi Road, Hefei, 230022, Anhui, China.

Endometrial diseases, including uterine fibroids, polyps, intrauterine adhesion, endometritis, etc., are the major causes of infertility among women. However, the association between essential trace element status in women and the risk of endometrial disease is limited and unclear. Read More

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Diagnosing chronic endometritis: when simplification fails to clarify.

Hum Reprod Open 2022 7;2022(3):hoac023. Epub 2022 Jun 7.

Next Fertility IVF Prof. Zech-Bregenz, Bregenz, Austria.

Reproductive immunology has grown in importance in recent years and has even developed into a discipline of its own within the field of reproductive medicine. Many aspects of reproductive failure such as repeated implantation failure or recurrent miscarriages are, meanwhile, seen as a consequence of aberrant expression of immunological factors. This is reflected by the increasing number of tests for assessing and quantifying different immune cell types as well as by a wide range of immune therapies offered to a clientele consisting of desperate patients requesting additional 'IVF tools': first, what is still usually disregarded is the enormous plasticity and fluctuation of most immune cells in the genital tract; second, their still poorly characterized functions in the endometrial cycle: further, their partially unknown role in embryo implantation and in establishing a pregnancy; and third, the fact that one of the fundamental hypotheses of reproductive immunology-of note-the Medawar concept or 'Medawar's Paradox' of semi-allogeneic graft embryo, is partially based on an erroneous assumption, i. Read More

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Prevalence of and risk factors for chronic endometritis in patients with intrauterine disorders after hysteroscopic surgery.

Fertil Steril 2022 Jun 16. Epub 2022 Jun 16.

Center for Reproductive Medicine and Implantation Research, Sugiyama Clinic Shinjuku, Tokyo, Japan.

Objective: To identify the prevalence of and risk factors for chronic endometritis (CE) in patients with intrauterine disorders and the therapeutic efficacy of hysteroscopic surgery in the treatment of CE without antibiotic therapy.

Design: Prospective cohort study.

Setting: Hospital specializing in reproductive medicine. Read More

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Medical management of secondary postpartum haemorrhage: A prospective cohort study.

Aust N Z J Obstet Gynaecol 2022 Jun 14. Epub 2022 Jun 14.

Department of Obstetrics and Gynaecology, Mercy Hospital for Women, Melbourne, Victoria, Australia.

Background: Secondary postpartum haemorrhage (PPH) complicates ~1% of pregnancies and can cause serious maternal morbidity. However, evidence guiding optimal management is scarce and often based on case series and expert opinion.

Aims: To measure the success of primary medical therapy in managing secondary PPH and to identify factors associated with need for surgical management. Read More

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The prevalence of gonococcal and non-gonococcal infections in women referred to obstetrics and gynecology clinics.

Infez Med 2022 1;30(2):247-253. Epub 2022 Jun 1.

Department of Microbiology, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.

Bacterial vaginosis is a condition caused by changes in the vaginal microbial ecosystem and increases the risk of preterm delivery, premature rupture of membranes, endometritis, and weight loss of the baby. This study aimed to evaluate the frequency of gonococcal and non-gonococcal genital infections in women referred to clinics in Ilam, Iran. Two swab samples were taken from each patient using a sterile swab, one swab was placed in a THB medium for the culture of and the other in PBS buffer for PCR. Read More

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Risk of spontaneous abortion after antibiotic therapy for chronic endometritis before in vitro fertilization and intracytoplasmic sperm injection stimulation.

Fertil Steril 2022 Jun 9. Epub 2022 Jun 9.

Reproductive Medicine Center, Northwest Women's and Children's Hospital, Xi'an, People's Republic of China. Electronic address:

Objective: To investigate whether cured chronic endometritis (CE) from antibiotic treatment would be associated with a higher risk of spontaneous abortion in the following in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) treatment.

Design: Prospective cohort study.

Setting: Tertiary reproductive medicine center. Read More

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Timing of Adjunctive Azithromycin for Unscheduled Cesarean Delivery and Postdelivery Infection.

Obstet Gynecol 2022 Jun 2;139(6):1043-1049. Epub 2022 May 2.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, the Center for Women's Reproductive Health, and the Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama; the Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, and Mission Hospital, Asheville, North Carolina; and the Departments of Obstetrics and Gynecology, University of Texas Medical Branch at Galveston, Galveston, Texas, Ochsner Health System, New Orleans, Louisiana, University of Utah and Intermountain Health Care, Salt Lake City, Utah, Columbia University, New York, New York, University of Mississippi, Jackson, Mississippi, University of Texas Health Sciences Center, Houston, Texas.

Objective: To estimate the association between timing of administration of adjunctive azithromycin for prophylaxis at unscheduled cesarean delivery and maternal infection and neonatal morbidity.

Methods: We conducted a secondary analysis of a randomized trial of adjunctive azithromycin prophylaxis in patients with singleton gestations who were undergoing unscheduled cesarean delivery. The primary exposure was the timing of initiation of the study drug (after skin incision or 0-30 minutes, more than 30-60 minutes, or more than 60 minutes before skin incision). Read More

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IFN-τ mediated miR-26a targeting PTEN to activate PI3K/AKT signalling to alleviate the inflammatory damage of bEECs.

Sci Rep 2022 Jun 7;12(1):9410. Epub 2022 Jun 7.

Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, People's Republic of China.

Endometritis is the failure of embryo implantation and an important cause of infertility in dairy cows. IFN-τ is a type I interferon unique to ruminants. In regulating the process of inflammatory response, IFN-τ can be expressed through MicroRNAs (miRNAs) to regulate the process of inflammation. Read More

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Single-dose versus multiple-dose antibiotics prophylaxis for preventing caesarean section postpartum infections: A randomized controlled trial.

Womens Health (Lond) 2022 Jan-Dec;18:17455057221101071

Department of Obstetrics and Gynaecology, Federal Medical Centre, Keffi, Nigeria.

Background: Caesarean section, a common obstetric surgical procedure, is a major predisposing factor for puerperal infections, requiring the need for antibiotic prophylaxis. Evidence suggests that single-dose antibiotic prophylaxis has comparable efficacy to multiple-dose antibiotic prophylaxis, but with a lower cost and risk of antibiotic resistance. However, single-dose antibiotic prophylaxis after caesarean section is not generally used in many centres in sub-Saharan Africa. Read More

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Bacteria Isolated From Equine Uteri in The United Arab Emirates: A Retrospective Study.

J Equine Vet Sci 2022 Jun 2;115:104029. Epub 2022 Jun 2.

Sharjah Equine Hospital, Al Atain, Sharjah, UAE. Electronic address:

The United Arab Emirates (UAE) presents a unique environment in which to breed horses with a non-physiological breeding season coupled with high temperatures and humidity for much of the year. This study aimed to describe bacterial isolates from the uteri of mares in the UAE and compare them to those reported elsewhere in the world. Bacterial antibiotic resistance was also analyzed to give a starting point for future monitoring. Read More

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Multi-drug-resistant chronic endometritis in infertile women with repeated implantation failure: trend over the decade and pilot study for third-line oral antibiotic treatment.

J Assist Reprod Genet 2022 Jun 2. Epub 2022 Jun 2.

Reproduction Clinic Osaka, Grand Front Osaka Tower-A 15F, 4-20 Oofuka-cho, Kita-ku, Osaka, 530-0011, Japan.

Purpose: To evaluate the yearly prevalence and annual transition of multi-drug-resistant-chronic endometritis (MDR-CE) in infertile women with a history of repeated implantation failure (RIF) and to establish the third-line antibiotic treatment regimen against MDR-CE.

Methods: This retrospective/prospective cohort and pilot study included 3473 RIF women between April 2010 and September 2021. The endometrial stromal plasmacyte density index (ESPDI) was calculated in 3449 CD138-immunostained endometrial sections to evaluate CE. Read More

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Bovine salpingitis: Histopathology, bacteriology, cytology and transcriptomic approaches and its impact on the oocyte competence.

Anim Reprod Sci 2022 Jul 22;242:107004. Epub 2022 May 22.

Department of Animal Reproduction, School of Veterinary Medicine, Shiraz University, Shiraz, Iran. Electronic address:

The present study was performed to examine the histopathology, cytology, bacteriology and expression pattern of a targeted set of genes of cytokines in the oviduct of cows with inflammation (Experiment 1). In addition, the effects of oviductal fluid from cows with salpingitis on the oocyte maturation and fertilization in vitro were examined (Experiment 2). The most frequent bacterial co-infection was Escherichia coli and Fusobacterium necrophorum, which was always associated with severe histopathologic salpingitis. Read More

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Baicalin alleviates endometrial inflammatory injury through regulation of tight junction proteins.

Food Funct 2022 Jun 20;13(12):6522-6533. Epub 2022 Jun 20.

College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.

Endometritis is the foremost reason for reduced reproductive performance, which impedes the establishment of pregnancy in ruminants. Baicalin is extensively acknowledged as a tocolytic drug. However, the preventive effect of baicalin on endometrial inflammatory injury remains unclear. Read More

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Subclinical endometritis differentially affects the transcriptomic profiles of endometrial glandular, luminal, and stromal cells of postpartum dairy cows.

J Dairy Sci 2022 Jul 28;105(7):6125-6143. Epub 2022 May 28.

Department of Clinical Sciences, Swedish University of Agricultural Sciences, SLU, PO Box 7054, 750 07 Uppsala, Sweden.

In postpartum dairy cows, subclinical endometritis (SCE) is characterized by persistent endometrial inflammation, which has profound detrimental effects on subsequent reproductive performance. To date, transcriptomic studies related to this condition were either based on biopsy-derived whole-endometrium tissue or endometrial swab or cytobrush samples, thus masking effects of disease on cell type-specific gene expression. This study tested the hypothesis that different endometrial health statuses are associated with distinct transcription profiles of endometrial stromal, glandular, and luminal epithelial cells. Read More

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Investigation of the Role of Pituitary Adenylate Cyclase-Activating Peptide (PACAP) and Its Type 1 (PAC1) Receptor in Uterine Contractility during Endometritis in Pigs.

Int J Mol Sci 2022 May 13;23(10). Epub 2022 May 13.

Division of Reproductive Biology, Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences, Tuwima 10, 10-078 Olsztyn, Poland.

Uterine inflammation is a common pathology in animals, leading to disturbances in reproductive processes and reduced production profitability. Pituitary adenylate cyclase-activating peptide (PACAP) effects at the uterine level during inflammation are not known. In the current study, we analyzed the relative PACAP type 1 receptor (PAC1R) mRNA transcript and protein abundances in the myometrium (MYO), as well s PACAP and PAC1R involvement in the contractile function of inflamed pig uterus. Read More

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Genetic Diversity, Biofilm Formation, and Antibiotic Resistance of Isolated from Cow, Camel, and Mare with Clinical Endometritis.

Vet Sci 2022 May 16;9(5). Epub 2022 May 16.

Department of Microbiology, Faculty of Veterinary Medicine, Assiut University, Assiut 71515, Egypt.

is a ubiquitous opportunistic bacterium that causes diseases in animals and humans. This study aimed to investigate the genetic diversity, antimicrobial resistance, biofilm formation, and virulence and antibiotic resistance genes of isolated from the uterus of cow, camel, and mare with clinical endometritis and their drinking water. Among the 180 uterine swabs and 90 drinking water samples analysed, 54 (20%) isolates were recovered. Read More

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Endometritis - Diagnosis,Treatment and its impact on fertility - A Scoping Review.

JBRA Assist Reprod 2022 May 27. Epub 2022 May 27.

Department of Obstetrics and Gynaecology All India Institute of Medical Sciences New Delhi India Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, New Delhi, India.

Endometritis is defined as an infection or inflammation of the endometrium. Endometritis is of two types: acute and chronic. Acute endometritis is the symptomatic acute inflammation of the endometrium, which upon examination with a microscope shows micro-abscess and neutrophil invasion in the superficial endometrium. Read More

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Medicinal Importance, Pharmacological Activities and Analytical Aspects of Engeletin in the Medicine: Therapeutic Benefit through Scientific Data Analysis.

Endocr Metab Immune Disord Drug Targets 2022 May 20. Epub 2022 May 20.

Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, 211007, Uttar Pradesh, India.

Background: Flavonoidal class phytocompounds have been used in the medicine for the treatment of numerous kinds of human health complications. Flavonoidal class phytocompounds have health beneficial aspects in medicine mainly due to its anti-microbial, anti-diabetic, anti-inflammatory, anti-cancer and anti-carcinogenic activities. Flavonoidal class phytocompounds have been well investigated in the scientific field for their health beneficial aspects and pharmacological activities against various forms of human complications. Read More

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Identifying causal relationships of cancer treatment and long-term health effects among 5-year survivors of childhood cancer in Southern Sweden.

Commun Med (Lond) 2022 2;2:21. Epub 2022 Mar 2.

Department of Clinical Sciences Lund, Pediatrics, Faculty of Medicine, Lund University, Lund, Sweden.

Background: Survivors of childhood cancer can develop adverse health events later in life. Infrequent occurrences and scarcity of structured information result in analytical and statistical challenges. Alternative statistical approaches are required to investigate the basis of late effects in smaller data sets. Read More

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Severity of intrapartum fever and neonatal outcomes.

Am J Obstet Gynecol 2022 May 19. Epub 2022 May 19.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Washington University School of Medicine in St. Louis, St. Louis, MO.

Background: The few studies that have addressed the relationship between severity of intrapartum fever and neonatal and maternal morbidity have had mixed results. The impact of the duration between reaching maximum intrapartum temperature and delivery on neonatal outcomes remains unknown.

Objective: To test the association of severity of intrapartum fever and duration from reaching maximum temperature to delivery with neonatal and maternal morbidity. Read More

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Research update for the immune microenvironment of chronic endometritis.

J Reprod Immunol 2022 May 11;152:103637. Epub 2022 May 11.

The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital), Shenzhen 518020, China; Hainan Vocational University of Science and Technology, No.18 Qiongshan Avenue, Meilan District, Haikou City 571126, Hainan Province, China; Shenzhen Children's Hospital Affiliated to Shantou University Medical College, Shenzhen 518038, China. Electronic address:

Chronic endometritis (CE) is a persistent and subtle local inflammatory disease characterized by abnormal plasma cell infiltration in the endometrial stroma.The incidence of chronic endometritis is as high as 15-57.5% in women suffering from infertility, implantation failure of in vitro fertilization (IVF) and unexplained recurrent abortion. Read More

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Vascular endothelial growth factor (VEGF) expression in histological endometritis in the bitch: An immunohistochemical study.

Reprod Domest Anim 2022 May 15. Epub 2022 May 15.

Instituto de Investigaciones en Reproducción Animal (INIRA), Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata, Argentina.

This work aimed to study the immunolocalization of vascular endothelial growth factor (VEGF) and its FLT-1 receptor (VEGFR1) in systemically healthy bitches with and without endometritis (END). Thirty-one uterine samples from mixed-breed, systemically healthy diestrous bitches, were included in the study. The bitches were divided into three groups after histological evaluation (normal endometrium [n = 8]; acute-END [n = 8]; subacute-END [n = 5]; chronic-END [n = 10]). Read More

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Infectious Inflammatory Processes and the Role of Bioactive Agent Released from Imino-Chitosan Derivatives Experimental and Theoretical Aspects.

Polymers (Basel) 2022 Apr 30;14(9). Epub 2022 Apr 30.

Department of Internal Medicine (Cardiology), "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.

The paper focuses on the development of a multifractal theoretical model for explaining drug release dynamics (drug release laws and drug release mechanisms of cellular and channel-type) through scale transitions in scale space correlated with experimental data. The mathematical model has been developed for a hydrogel system prepared from chitosan and an antimicrobial aldehyde via covalent imine bonds. The reversible nature of the imine linkage points for a progressive release of the antimicrobial aldehyde is controlled by the reaction equilibrium shifting to the reagents, which in turn is triggered by aldehyde consumption in the inhibition of the microbial growth. Read More

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Fluorescence Spectroscopy for the Diagnosis of Endometritis in the Mare.

Animals (Basel) 2022 Apr 29;12(9). Epub 2022 Apr 29.

Department of Sciences, University of Basilicata, Campus Macchia Romana, 85100 Potenza, Italy.

By exploiting the PMN property to produce high quantities of oxygen peroxide to neutralize pathogens, the oxygen peroxide content of uterine cells was measured to diagnose endometritis. After preliminary in vitro studies in which endometrial cells from slaughtered mares were mixed with leukocytes from peripheral blood, endometrial samples were collected by uterine flushing from mares before insemination. Staining endometrial cells with HDCF-DA was combined with hydroethidine to normalize the fluorescence intensity with the cellular content of the sample. Read More

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Inhibition of Neutrophil Extracellular Traps Formation by Cl-Amidine Alleviates Lipopolysaccharide-Induced Endometritis and Uterine Tissue Damage.

Animals (Basel) 2022 Apr 29;12(9). Epub 2022 Apr 29.

Lanzhou Institute of Husbandry and Pharmaceutical Science, Chinese Academy of Agricultural Science, Lanzhou 730050, China.

Endometritis is a common disease that affects the production in dairy cows and leads to severe losses in the dairy industry. Neutrophil extracellular traps (NETs) formation promotes pathogenic invasions of the lumen of the tissue, leading to inflammatory diseases such as mastitis, pancreatitis, and septic infection. However, research that could show the relationship between NETs and endometritis is scarce. Read More

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Placental Abruption and Partial Placental Prolapse During Induction of Labor in a 31-Year-Old Female With Intrahepatic Cholestasis of Pregnancy: A Case Report.

Cureus 2022 Apr 9;14(4):e23995. Epub 2022 Apr 9.

Obstetrics/Gynecology, West Suburban Medical Center, Chicago, USA.

Placental abruption during induction of labor in females with intrahepatic cholestasis of pregnancy is not exceptionally common and there are no documented reports of placental prolapse following abruption in the literature. The aim of this study is to discuss the possibility of placental abruption and partial prolapse of a low-lying placenta during a prolonged induction of labor in a female with recurrent intrahepatic cholestasis of pregnancy following a cholecystectomy. We describe a 31-year-old G4P3003 female with recurrent intrahepatic cholestasis of pregnancy, with no family history of the condition and surgical history of cholecystectomy, whose induction of labor at 37+3/7 gestational weeks for intrahepatic cholestasis of pregnancy was complicated by placental abruption and partial prolapse of the low-lying placenta. Read More

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