5,876 results match your criteria Endometritis


Field trial on the post-insemination intrauterine treatment of dairy cows with mild endometritis with cephapirin.

Theriogenology 2020 Jun 29;156:20-26. Epub 2020 Jun 29.

Clinical Unit for Herd Health Management in Ruminants, University Clinic for Ruminants, Department of Farm Animals and Veterinary Public Health, University of Veterinary Medicine Vienna, Veterinärplatz 1, 1210, Vienna, Austria.

Cows in estrus but with signs of clinical endometritis (CE) are often not inseminated or undergo an intrauterine treatment after artificial insemination (AI). Decades ago, the so-called Aström method was described as intrauterine infusion of iodine-potassium solution 2-4 days after AI. Nowadays, it is common to use antibiotics instead of iodine solution and the treatment is performed only a few hours after AI. Read More

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http://dx.doi.org/10.1016/j.theriogenology.2020.06.024DOI Listing

Inflammation changes the expression of neuropeptide Y receptors in the pig myometrium and their role in the uterine contractility.

PLoS One 2020 10;15(7):e0236044. Epub 2020 Jul 10.

Division of Clinical Physiology, Faculty of Veterinary Medicine, University of Warmia and Mazury, Olsztyn, Poland.

In the experiment the influence of inflammation on neuropeptide Y (NPY) receptor subtype 1 (Y1Rs) and 2 (Y2Rs) expression pattern in the gilt myometrium and NPY effect alone or with Y1Rs and Y2Rs antagonists on contractility of an inflamed uterus were recognized. On Day 3 of the estrous cycle, either E.coli suspension (E. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0236044PLOS

Maternal Outcomes of Ongoing Pregnancies Complicated by Fetal Life-Limiting Conditions.

Am J Perinatol 2020 Jul 9. Epub 2020 Jul 9.

Department of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, Wisconsin.

Objective:  This study aimed to examine maternal outcomes of ongoing pregnancies complicated by fetal life-limiting conditions.

Study Design:  This was a retrospective matched cohort study of women with a diagnosis of fetal life-limiting condition between 2010 and 2018 in a single academic center. Cases were matched to controls (women who had normal fetal anatomic survey) according to year of delivery, body mass index, and parity in a 1:4 ratio. Read More

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http://dx.doi.org/10.1055/s-0040-1713927DOI Listing

Candidate genes for age at menarche are associated with endometrial hyperplasia.

Gene 2020 Jul 5:144933. Epub 2020 Jul 5.

Department of Medical Biological Disciplines, Belgorod State University, 308015 Belgorod, Russia.

Objectives: To study associations candidate genes for age at menarche with a risk of endometrial hyperplasia (EH).

Methods: 52 candidate loci for age at menarche were analyzed for possible association with EH in a sample of 520 patients and 981 controls. Association of the polymorphisms was analyzed using the method of logistic regression. Read More

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http://dx.doi.org/10.1016/j.gene.2020.144933DOI Listing

The association of skin incision placement during cesarean delivery with wound complications in obese women: a systematic review and meta-analysis.

J Matern Fetal Neonatal Med 2020 Jul 7:1-13. Epub 2020 Jul 7.

Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Thomas Jefferson University Hospital, Philadelphia, PA, USA.

Objective: To determine the risk of wound complications by skin incision type in obese women undergoing cesarean delivery. Electronic databases (MEDLINE, Scopus, and Ovid) were searched from their inception through August 2018. We included all randomized controlled trials and cohort studies reporting the placement of skin incision during cesarean section in obese women, defined as those with BMI ≥30 kg/m. Read More

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http://dx.doi.org/10.1080/14767058.2020.1786050DOI Listing

Case Report: Use of Amniotic Microvesicles for Regenerative Medicine Treatment of a Mare With Chronic Endometritis.

Front Vet Sci 2020 17;7:347. Epub 2020 Jun 17.

Department of Veterinary Medicine (DIMEVET), Università degli Studi di Milano, Via dell'Università, Lodi, Italy.

Chronic endometritis is an inflammation in the inner layer of uterine mucosa, with or without an infectious process, which affects the animal's fertility but not its general health. A variety of treatments has been adopted over the years but to date, no effective cures have been able to renew the injured tissue. Since the defects in the fetal-maternal communication are caused by degenerative changes due to chronic endometrial inflammation, our working hypothesis was a new approach to this disease by the regenerative medicine using amniotic derived microvesicles (MVs) for their anti-inflammatory and regenerative effects. Read More

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http://dx.doi.org/10.3389/fvets.2020.00347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311574PMC

Metabolic markers for purulent vaginal discharge and subclinical endometritis in dairy cows.

Theriogenology 2020 Jun 8;155:43-48. Epub 2020 Jun 8.

Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.

This study compares serum markers for systemic inflammation, and liver, mineral, and energy status in samples obtained -7, 1, 3, 5, 7, 14 ± 1, 21 ± 1, and 35 d relative to calving from healthy dairy cows and those diagnosed with purulent vaginal discharge (PVD) or subclinical endometritis (SCE). Metabolites and markers measured in serum were total calcium, total protein, albumin, globulin, cholesterol, urea, glucose, gamma-glutamyl transferase, aspartate aminotransferase, glutamate dehydrogenase, β-hydroxybutyrate (BHB), non-esterified fatty acids (NEFA), haptoglobin (Hp), and insulin-like growth factor-1 (IGF-1). Holstein cows with no recorded clinical disease were classified healthy (neither PVD nor SCE; n = 38), PVD (n = 10) or SCE (n = 10) at 35 d postpartum. Read More

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http://dx.doi.org/10.1016/j.theriogenology.2020.06.005DOI Listing

Assessment of the anti-inflammatory and engraftment potential of horse endometrial and adipose mesenchymal stem cells in an in vivo model of post breeding induced endometritis.

Theriogenology 2020 Jun 14;155:33-42. Epub 2020 Jun 14.

Department of Animal Science, Faculty of Veterinary Sciences, Universidad de Concepción, Chillán, Chile. Electronic address:

Horse mesenchymal stem cells (MSC) are potential anti-inflammatory tools for post-breeding induced endometritis (PBIE). In this research MSCs isolated from the endometrium or subcutaneous fat of the same donors were infused iu into mares with PBIE for assessment of their anti-inflammatory action and engraftment. PBIE was induced in nine gynecologically healthy mares by iu infusion of 500 million dead sperm in saline. Read More

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http://dx.doi.org/10.1016/j.theriogenology.2020.06.010DOI Listing

The advantages of using cytospins of uterine lavage fluid for the diagnosis of equine endometritis.

Theriogenology 2020 May 21;154:143-151. Epub 2020 May 21.

Animal Reproduction Center of Vairão, ICBAS-UP, Portugal.

Uterine lavage (UL) is a routine diagnostic procedure for endometritis. In UL the fluid is centrifuged and the sediment smeared. Samples prepared in cytocentrifuges, the so-called "cytospins", are useful for evaluating cells in fluids, but never been used in UL. Read More

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http://dx.doi.org/10.1016/j.theriogenology.2020.05.008DOI Listing

Hysterectomy and Oophorectomy in Reproductive Age: A Cross-Sectional Study from a Tertiary Care Hospital.

Cureus 2020 May 28;12(5):e8344. Epub 2020 May 28.

Pathology, Dow Medical College, Dow University of Health Sciences, Karachi, PAK.

Introduction Hysterectomy is a common surgical procedure in women, and oophorectomy may also be performed with the hysterectomy. The objective of this study was to identify clinical indications and pathological findings in hysterectomies, performed for gynecological causes, in women of reproductive age (15-49 years) and to determine if oophorectomy or ovarian conservation was performed with the hysterectomy as well as the pathological findings in the ovaries. Methods This cross-sectional study was conducted in the department of Pathology at Dow Medical College in Karachi, Pakistan, from September 2017 to December 2018. Read More

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http://dx.doi.org/10.7759/cureus.8344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325352PMC

Estimating prevalence of endometritis in smallholder zero-grazed dairy cows in Rwanda.

Trop Anim Health Prod 2020 Jun 25. Epub 2020 Jun 25.

Department of Animal Sciences, Faculty of Agriculture, Egerton University, P. O. Box 536, Njoro, 20115, Kenya.

Endometritis is a postpartum uterine disease of cows that interrupts reproductive cycles resulting in suboptimal fertility, reduced performance and profitability of the dairy herd. The objective of the study was to estimate the perceived and observed prevalence of endometritis among zero-grazed dairy cows in smallholder farms in Rwanda. A snowball sampling method was applied in cross-sectional survey to obtain data from 370 farms on 466 cows within their 21-60 days postpartum (dpp). Read More

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http://dx.doi.org/10.1007/s11250-020-02337-zDOI Listing

Skin preparation for preventing infection following caesarean section.

Cochrane Database Syst Rev 2020 06 25;6:CD007462. Epub 2020 Jun 25.

Global Health Nursing, Graduate School of Nursing Science, St. Luke's International University, Tokyo, Japan.

Background: The risk of maternal mortality and morbidity is higher after caesarean section than for vaginal birth. With increasing rates of caesarean section, it is important to minimise risks to the mother as much as possible. This review focused on different skin preparations to prevent infection. Read More

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http://dx.doi.org/10.1002/14651858.CD007462.pub5DOI Listing

In women with chronic or subclinical endometritis is hysteroscopy suitable for setting the diagnosis? A systematic review.

J Obstet Gynaecol Res 2020 Jun 23. Epub 2020 Jun 23.

Department of Obstetrics and Gynaecology, University Hospital of Ioannina, Ioannina, Greece.

The role of hysteroscopy in cases of chronic or subclinical endometritis remains uncertain. Reevaluating the clinical relevance of diagnostic hysteroscopic in these cases will improve the level of case in women's health worldwide. The objective of this systematic review was to assess the suitability of hysteroscopy in detecting and diagnosing female patients with chronic or subclinical endometritis, as a first-line diagnostic tool. Read More

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http://dx.doi.org/10.1111/jog.14360DOI Listing

Pregnancy and delivery in women with a high risk of infection in pregnancy.

J Matern Fetal Neonatal Med 2020 Jun 23:1-6. Epub 2020 Jun 23.

Federal State Funded Educational Institution for Higher Education Omsk State Medical University, Ministry of Public Health, Russian Federation.

Pregnant women with chronic genital and non-genital infections are at a high risk of infections complication during pregnancy and the postpartum period. Preterm birth is one of the leading causes of obstetric and neonatal complications and occurs in one in nine women. Forty per cent of preterm births are considered to be caused by the abnormal vaginal microbiome, and there is currently no consensus on the contribution of combined bacterial and viral infections. Read More

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http://dx.doi.org/10.1080/14767058.2020.1781810DOI Listing

Maternal and neonatal outcomes following a prolonged second stage of labor: A meta-analysis of observational studies.

Eur J Obstet Gynecol Reprod Biol 2020 Jun 10;252:62-69. Epub 2020 Jun 10.

1(st)department of Obstetrics and Gynecology, Alexandra Hospital, National and Kapodistrian University of Athens, Greece.

Several articles investigated the impact of prolonged second stage of labor on maternal and neonatal outcomes; however, strict consensus is still lacking. The purpose of the present meta-analysis is to investigate risk factors that contribute to the pathophysiology of prolonged labor as well as effect sizes of maternal and neonatal morbidity. We searched Medline, Scopus, Clinicaltrials. Read More

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http://dx.doi.org/10.1016/j.ejogrb.2020.06.018DOI Listing

Adipokines as biomarkers of postpartum subclinical endometritis in dairy cows.

Reproduction 2020 Jun 1. Epub 2020 Jun 1.

L Lopes-da-Costa, Reproduction and Development, CIISA - Centro de Investigação Interdisciplinar em Sanidade Animal, Faculdade de Medicina Veterinária, Universidade de Lisboa, Lisboa, Portugal.

Adipokines emerged as regulators of metabolism and inflammation in several scenarios. This study evaluated the relationship between adipokines (adiponectin, chemerin and visfatin) and cytological (subclinical) endometritis, by comparing healthy (without), transient (recovered by 45 days postpartum (DPP)) and persistent (until 45 DPP) endometritis cows (n = 49). Cows with persistent endometritis had higher adiponectin concentrations in plasma (at 21 DPP, P < 0. Read More

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http://dx.doi.org/10.1530/REP-20-0183DOI Listing

[Establishment and evaluation of multiplex PCR for detection of main pathogenic bacteria of endometritis in Tibetan sheep].

Sheng Wu Gong Cheng Xue Bao 2020 May;36(5):908-919

Technology and Research Center of Gansu Province for Embryo Engineering of Bovine and Sheep& Goat, College of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, Gansu, China.

A multiplex PCR method was developed to detect the main pathogens of Qinghai Tibetan sheep endometritis. First, the genomes of five standard bacterial strains were extracted and specific primers were selected; the multiplex PCR method was established by using the genome of the standard strain as a template. The samples were collected by sterile cotton swab from Tibetan sheep uterus, and then placed in LB medium and numbered. Read More

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http://dx.doi.org/10.13345/j.cjb.190365DOI Listing

The Influence of Academic Hospitalists on Labor and Delivery Outcomes.

Gynecol Obstet Invest 2020 Jun 9:1-5. Epub 2020 Jun 9.

Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA,

Background: Our goal was to examine differences in maternal and neonatal outcomes following the transition from a private practice to an academic model at a community hospital.

Methods: This is a retrospective cohort study of a high-volume community hospital labor and delivery unit. A private practice hospitalist group was replaced with academic hospitalists. Read More

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http://dx.doi.org/10.1159/000508246DOI Listing

Clinical, ultrasonographic, bacteriological, cytological and histological findings during uterine involution in ewes with pregnancy toxaemia and subsequent reproductive efficiency.

Anim Reprod Sci 2020 Jul 26;218:106460. Epub 2020 Apr 26.

Veterinary Faculty, University of Thessaly, 43100 Karditsa, Greece. Electronic address:

Objectives were to evaluate characteristics of uterine involution in ewes with pregnancy toxaemia during gestation and to study effects on subsequent reproductive performance. Pregnancy toxaemia was induced in ewes (A) by feeding an energy-deficient diet as confirmed by detecting β-hydroxybutyrate concentrations in blood indicative of this disorder. There was also a control group (C). Read More

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http://dx.doi.org/10.1016/j.anireprosci.2020.106460DOI Listing

Therapeutic potential of a designed CSαβ peptide ID13 in Staphylococcus aureus-induced endometritis of mice.

Appl Microbiol Biotechnol 2020 Aug 6;104(15):6693-6705. Epub 2020 Jun 6.

Team of Alternatives to Antibiotics, Gene Engineering Lab, Feed Research Institute, Chinese Academy of Agricultural Science, Beijing, 100081, People's Republic of China.

Staphylococcus aureus is a common pathogen that can cause clinical and subclinical endometritis in humans and animals. In this study, a designed CSαβ peptide ID13 from DLP4 exhibited high stable antibacterial activity in simulated gastric fluid (90.79%), serum (99. Read More

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http://dx.doi.org/10.1007/s00253-020-10685-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275135PMC

Revealing active ingredients, potential targets, and action mechanism of Ermiao fang for treating endometritis based on network pharmacology strategy.

J Ethnopharmacol 2020 Jun 4;260:113051. Epub 2020 Jun 4.

Department of Traditional Chinese Medicine, South Campus, Ren Ji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 201112, China. Electronic address:

Ethnopharmacological Relevance: Ermiao fang (EMF) is a traditional Chinese medicinal herbal formula from ancient times and recorded in the pharmacopeia of the People's Republic of China. It is composed of two typical Chinese herbal medicines, Cortex Phellodendri (Huangbai), the bark of Phellodendron chinensis Schneid. (Rutaceae), and Rhizoma Atractylodis (Cangzhu), the rhizome of Atractylodes lancea (Thunb. Read More

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http://dx.doi.org/10.1016/j.jep.2020.113051DOI Listing
June 2020
2.998 Impact Factor

Perception of farmers about endometritis prevention and control measures for zero-grazed dairy cows on smallholder farms in Rwanda.

BMC Vet Res 2020 Jun 5;16(1):175. Epub 2020 Jun 5.

Department of Animal Sciences, Faculty of Agriculture, Egerton University, P.O; Box 536, Egerton, Kenya.

Background: Endometritis is a prevalent uterine disease in postpartum cows. The disease reduces fertility performance and milk yield, and subsequently, productivity and profitability of dairy farms. The reduction in performance is associated with considerable economic losses on dairy farms. Read More

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http://dx.doi.org/10.1186/s12917-020-02368-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275537PMC

The efficacy of two doses versus 7 days' course of prophylactic antibiotics following cesarean section: An experience from Aminu Kano Teaching Hospital.

Ann Afr Med 2020 Apr-Jun;19(2):103-112

Department of Obstetrics and Gynaecology, Bayero University Kano/Aminu Kano Teaching Hospital, Kano, Nigeria.

Background: Postcesarean wound infection is a leading cause of prolonged hospital stay. Considerable debates still exist regarding choice of antibiotics, dose, and duration of use.

Objectives: The objective is to compare the efficacy of 2 doses of amoxicillin-clavulanic acid versus a 7 days combination of amoxicillin-clavulanic acid and metronidazole as prophylactic antibiotics following cesarean section (CS). Read More

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http://dx.doi.org/10.4103/aam.aam_39_19DOI Listing

Genital TB screening at an academic fertility center in the US.

Am J Obstet Gynecol 2020 Jun 1. Epub 2020 Jun 1.

Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut, USA.

Background: Infertility is a common presentation of female genital tuberculosis (FGTB) in endemic areas. FGTB-related maternal and neonatal complications have increased in recent years following assisted-reproductive technology treatments. Despite rising emigration rates to the United States, guidelines to identify those with latent TB or FGTB in fertility centers do not exist. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.05.045DOI Listing

LPS-treatment of bovine endometrial epithelial cells causes differential DNA methylation of genes associated with inflammation and endometrial function.

BMC Genomics 2020 Jun 3;21(1):385. Epub 2020 Jun 3.

Department of Clinical Sciences, Division of Reproduction, Swedish University of Agricultural Sciences, Uppsala, 750 07, Sweden.

Background: Lipopolysaccharide (LPS) endotoxin stimulates pro-inflammatory pathways and is a key player in the pathological mechanisms involved in the development of endometritis. This study aimed to investigate LPS-induced DNA methylation changes in bovine endometrial epithelial cells (bEECs), which may affect endometrial function. Following in vitro culture, bEECs from three cows were either untreated (0) or exposed to 2 and 8 μg/mL LPS for 24 h. Read More

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http://dx.doi.org/10.1186/s12864-020-06777-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268755PMC

Relationship of chronic endometritis with chronic deciduitis in cases of miscarriage.

BMC Womens Health 2020 Jun 1;20(1):114. Epub 2020 Jun 1.

Department of Obstetrics and Gynecology, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan.

Background: The presence of chronic deciduitis (CD) was determined in patients diagnosed with or without chronic endometritis (CE) before pregnancy.

Objective: To study the effect of CE on decidua in cases of miscarriage.

Methods: Decidual tissue was obtained from the patients who miscarried at the first pregnancy within a year after the diagnosis of the presence or absence of CE. Read More

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http://dx.doi.org/10.1186/s12905-020-00982-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268368PMC

Characterization of native Escherichia coli populations from bovine vagina of healthy heifers and cows with postpartum uterine disease.

PLoS One 2020 1;15(6):e0228294. Epub 2020 Jun 1.

Instituto Superior de Investigaciones Biológicas (INSIBIO), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), San Miguel de Tucumán, Tucumán, Argentina.

Even though Escherichia coli are common bacteria of the bovine vaginal microbiota, they represent an important pathogen that causes diseases in the reproductive tract and subfertility. However, the actual endometrial virulence profile of E. coli is poorly understood. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0228294PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263596PMC

A Gap in Care? Postpartum Women Presenting to the Emergency Room and Getting Readmitted.

Am J Perinatol 2020 May 30. Epub 2020 May 30.

Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas.

Objective:  Emergent postpartum hospital encounters in the first 42 days after birth are estimated to complicate 5 to 12% of births. Approximately 2% of these visits result in admission. Data on emergent visits and admissions are critically needed to address the current maternal morbidity crisis. Read More

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http://dx.doi.org/10.1055/s-0040-1712170DOI Listing

Streptococcus uberis strains originating from bovine uteri provoke upregulation of pro-inflammatory factors mRNA expression of endometrial epithelial cells in vitro.

Vet Microbiol 2020 Jun 5;245:108710. Epub 2020 May 5.

Functional Microbiology, Institute for Microbiology, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria. Electronic address:

Streptococcus uberis is an opportunistic pathogen involved in various infections of cattle. It is a well-known etiological agent of bovine mastitis and has recently also been linked to postpartum endometritis in dairy cows. S. Read More

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http://dx.doi.org/10.1016/j.vetmic.2020.108710DOI Listing

Uterine body placenta accreta spectrum: A detailed literature review.

Placenta 2020 Jun 26;95:44-52. Epub 2020 Apr 26.

Makassed General Hospital, Beirut, Lebanon.

Placenta accreta spectrum (PAS) is a major obstetrical problem whose incidence is rising. Current guidelines recommend screening of all women with placenta previa and risk factors for PAS between 20 and 24 weeks. Risk factors, diagnosis, and management of previa PAS are well established, but an apparently normal location of the placenta does not exclude PAS. Read More

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http://dx.doi.org/10.1016/j.placenta.2020.04.005DOI Listing
June 2020
2.710 Impact Factor

Is Group B Streptococcus Colonization Associated with Maternal Peripartum Infection in an Era of Routine Prophylaxis?

Am J Perinatol 2020 May 23. Epub 2020 May 23.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University, Durham, North Carolina.

Objective:  This study aimed to assess whether colonization with group B streptococcus (GBS) is associated with maternal peripartum infection in an era of routine prophylaxis.

Study Design:  This study presented a secondary analysis of women delivering ≥37 weeks who underwent a trial of labor from the U.S. Read More

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http://dx.doi.org/10.1055/s-0040-1709666DOI Listing

Intrauterine therapy with ozone reduces subclinical endometritis and improves reproductive performance in postpartum dairy cows managed in pasture-based systems.

Trop Anim Health Prod 2020 May 22. Epub 2020 May 22.

Instituto Nacional de Investigación Agropecuaria (INIA), Ruta 50 km 11.5, Colonia del Sacramento, Uruguay.

New postpartum strategies have been developed in dairy cows to ameliorate uterine health and reproductive performance, especially the first service conception rates. This study aimed to assess the effect of intrauterine therapy with ozone (IUTO) in early postpartum on subclinical endometritis prevalence and reproductive parameters in dairy cows under commercial farm conditions. For this purpose, eighty clinically healthy cows with a body condition score between 3. Read More

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http://dx.doi.org/10.1007/s11250-020-02298-3DOI Listing

Endometritis Changes the Neurochemical Characteristics of the Caudal Mesenteric Ganglion Neurons Supplying the Gilt Uterus.

Animals (Basel) 2020 May 20;10(5). Epub 2020 May 20.

Department of Clinical Physiology, Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowskiego 14, 11-041 Olsztyn, Poland.

This study analyzed the influence of uterine inflammation on the neurochemical characteristics of the gilt caudal mesenteric ganglion (CaMG) uterus-supplying neurons. The horns of uteri were injected with retrograde tracer Fast Blue on day 17 of the first studied estrous cycle. Twenty-eight days later (the expected day 3 of the third studied estrous cycle), either saline or suspension were administered into each uterine horn. Read More

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http://dx.doi.org/10.3390/ani10050891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278384PMC

Variation of diagnostic criteria in women with chronic endometritis and its effect on reproductive outcomes: A systematic review and meta-analysis.

J Reprod Immunol 2020 Aug 19;140:103146. Epub 2020 May 19.

Reproductive Medical Center, the First Affiliated Hospital of Guangxi Medical University, Nanning, China. Electronic address:

This meta-analysis aimed to evaluate the variation in the diagnostic criteria for chronic endometritis (CE) and its effect on reproductive outcomes. A search of the academic literature was conducted in various databases including PubMed, Embase, Cochrane Library, and Chinese National Knowledge Internet. Studies published in English or Chinese prior to October 1, 2019, were included in the primary screen. Read More

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http://dx.doi.org/10.1016/j.jri.2020.103146DOI Listing

Decreasing of S100A4 in bovine endometritis in vivo and in vitro.

Theriogenology 2020 Sep 12;153:68-73. Epub 2020 May 12.

Key Laboratory of Veterinary Pharmaceutical Development of Ministry of Agriculture, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of CAAS, Lanzhou, 730050, PR China. Electronic address:

Endometritis is a prevalent reproductive disease in dairy cows, and is a superficial inflammation of the endometrium. S100 calcium-binding protein A4 (S100A4) is suggested to be implicated in the progression of inflammation. However, to our knowledge, no study has reported the changes of S100A4 during bovine endometritis. Read More

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http://dx.doi.org/10.1016/j.theriogenology.2020.05.015DOI Listing
September 2020

Pregnancy related pharmacokinetics and antimicrobial prophylaxis during fetal surgery, cefazolin and clindamycin as examples.

Prenat Diagn 2020 May 22. Epub 2020 May 22.

Department of Pharmacy, Erasmus University Medical Center, Rotterdam, The Netherlands.

Antimicrobial prophylaxis during surgery aims to prevent post-operative site infections. For fetal surgery, this includes the fetal and amniotic compartments. Both are deep compartments as drug equilibrium with maternal blood is achieved relatively late. Read More

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http://dx.doi.org/10.1002/pd.5753DOI Listing

Isolation and characteristics of multi-drug resistant Streptococcus porcinus from the vaginal secretions of sow with endometritis.

BMC Vet Res 2020 May 20;16(1):146. Epub 2020 May 20.

Hebei Province Research Center of Veterinary Biological Engineering and Technology, College of Veterinary Medicine, Hebei Agricultural University, Baoding, 071000, China.

Background: Sow endometritis is a common disease in pig breeding farms after artificial insemination, which leads to gray-green vaginal secretions and decreased conception rates. It is important to perform an etiologic diagnosis for effective treatments and control of diseases. The aim of this study was to carry out a pathogenic detection in five specimens of vaginal secretions collected from sick pigs with endometritis, implement identification of the pathogens by phenotypic detection and 16 s rDNA sequence and phylogeny analysis, and determinate antibiotic susceptibility of the isolates. Read More

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http://dx.doi.org/10.1186/s12917-020-02365-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238638PMC

The In Vitro Inhibitory Effect of Sivelestat on Elastase Induced Collagen and Metallopeptidase Expression in Equine Endometrium.

Animals (Basel) 2020 May 16;10(5). Epub 2020 May 16.

CIISA-Centre for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medicine, University of Lisbon, 1300-477 Lisbon, Portugal.

Neutrophil extracellular traps (NETs) fight endometritis, and elastase (ELA), a protease found in NETs, might induce collagen type I (COL1) accumulation in equine endometrium. Metallopeptidases (MMPs) are involved in extracellular matrix balance. The aim was to evaluate the effects of ELA and sivelestat (selective elastase inhibitor) on MMP-2 and MMP-9 expression and gelatinolytic activity, as well as the potential inhibitory effect of sivelestat on ELA-induced COL1 in equine endometrium. Read More

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http://dx.doi.org/10.3390/ani10050863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278485PMC

Anti-inflammatory Effect of Astragalin and Chlorogenic Acid on -Induced Inflammation of Sheep Endometrial Epithelium Cells.

Front Vet Sci 2020 30;7:201. Epub 2020 Apr 30.

College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, China.

Endometritis is one of the main diseases which harm sheep husbandry. Astragalin and chlorogenic acid (CGA) are common active ingredients of traditional Chinese medicine (TCM) with immunoprotective, antioxidant, and anti-inflammatory properties. In the present study, sheep endometrial epithelium cells (SEECs) were successfully purified and identified, and the inflammation model of SEECs induced by was successfully established. Read More

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http://dx.doi.org/10.3389/fvets.2020.00201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205036PMC

Risk Factors for Postpartum Maternal Infection Following Spontaneous Vaginal Delivery Complicated by Chorioamnionitis.

AJP Rep 2020 Apr 15;10(2):e159-e164. Epub 2020 May 15.

Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina.

 Guidelines for the management of chorioamnionitis include intrapartum antibiotics, while postpartum antibiotics after spontaneous vaginal delivery (SVD) are reserved high-risk women. Our objective is to describe the incidence of and risk factors for postpartum infection after SVD complicated by chorioamnionitis.  This is a retrospective study of SVDs with clinically diagnosed chorioamnionitis at a single center. Read More

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http://dx.doi.org/10.1055/s-0040-1709983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228805PMC

Can we induce labor by mechanical methods following preterm premature rupture of membranes?

J Gynecol Obstet Hum Reprod 2020 May 15:101745. Epub 2020 May 15.

CHRU Lille, Clinique d'Obstétrique, F-59000, Lille,France; Université de Lille, EA 4489, Environnement Périnatal et Santé, F-59000, Lille,France.

Objective: To evaluate the use of the intracervical balloon compared with locally applied prostaglandins for cervical ripening for induction in patients with preterm premature rupture of membranes.

Methods: Monocentric, retrospective (from 2002 to 2017) observational cohort study of singleton pregnancies complicated by preterm premature rupture of membranes and induced between 34 and 37 weeks. The primary outcome measure was balloon catheter efficiency evaluated by Cesarean section rate. Read More

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http://dx.doi.org/10.1016/j.jogoh.2020.101745DOI Listing

Comparison of maternal and fetal complications in pregnant women with breech presentation undergoing spontaneous or induced vaginal delivery, or cesarean delivery.

Taiwan J Obstet Gynecol 2020 May;59(3):392-397

Department of Obstetrics and Gynecology, Istanbul Medeniyet University Goztepe Education and Research Hospital, Doktor Erkin caddesi, Kadıkoy/Istanbul, Turkey. Electronic address:

Objective: Breech presentation is the most common form of malpresentation, and associated with perinatal asphyxia and mortality, and maternal morbidity. Data associated with labor induction in breech presentation are limited. The aim of this study was to compare maternal and fetal complication rates in induced and spontaneous vaginal, and cesarean delivery with breech presentation. Read More

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http://dx.doi.org/10.1016/j.tjog.2020.03.010DOI Listing

TLR2/4 promotes PGE production to increase tissue damage in Escherichia coli-infected bovine endometrial explants via MyD88/p38 MAPK pathway.

Theriogenology 2020 Aug 7;152:129-138. Epub 2020 Apr 7.

Key Laboratory of Clinical Diagnosis and Treatment Techniques of Animal Disease for Ministry of Agriculture, College of Veterinary Medicine, Inner Mongolia Agricultural University, Huhhot, China. Electronic address:

Prostaglandin E2 (PGE), a lipid mediator, is released by several cell types including endometrial cells and plays a central role in bacterial infection of the endometrium during inflammation. PGE production accumulated in Escherichia coli (E. coli) -infected bovine endometrial tissue, which increased E. Read More

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http://dx.doi.org/10.1016/j.theriogenology.2020.04.004DOI Listing

Study To Reduce Infection Prior to Elective Cesarean Deliveries (STRIPES): a randomized clinical trial of chlorhexidine.

Am J Obstet Gynecol 2020 Jul 12;223(1):113.e1-113.e11. Epub 2020 May 12.

Department of Obstetrics, Gynecology and Reproductive Sciences, Icahn School of Medicine at Mount Sinai, New York, NY.

Background: Surgical site infections after cesarean delivery are a cause of maternal morbidity and are typically caused by skin microbial flora. Preadmission application of chlorhexidine gluconate using impregnated cloths may decrease surgical site infections by decreasing the abundance of microbial flora.

Objective: To determine whether the application of chlorhexidine gluconate cloths the night before and the morning of scheduled cesarean delivery decreases the risk of surgical site infections by 6 weeks postoperatively compared with placebo. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.05.021DOI Listing

Spontaneous pelvic inflammatory disease; Case report and review of the literature.

IDCases 2020 5;20:e00785. Epub 2020 May 5.

University of Maryland Medical Center, Department of Medicine, Division of Infectious Disease. 22 South Greene St, Baltimore MD 21201, United States.

gynecological infections generally occur in association with childbirth, intra-uterine devices, and other invasive gynecologic procedures, but rarely cause spontaneous pelvic inflammatory disease. We describe a case of a healthy young woman with spontaneous pelvic inflammatory disease, bacteremia, and shock, and summarize an additional 13 cases found in the literature. The majority were bacteremic and a significant number were also hypotensive. Read More

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http://dx.doi.org/10.1016/j.idcr.2020.e00785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210579PMC

Experimentally induced endometritis impairs the developmental capacity of bovine oocytes.

Biol Reprod 2020 May 13. Epub 2020 May 13.

Department of Animal Sciences, University of Florida, Gainesville FL 32611.

Uterine infection is associated with infertility in women and dairy cows, even after the resolution of infection. However, the mechanisms causing this persistent infertility are unclear. Here, we hypothesized that induced endometritis in non-lactating dairy cows would reduce the developmental competence of oocytes. Read More

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http://dx.doi.org/10.1093/biolre/ioaa069DOI Listing
May 2020
3.318 Impact Factor

Combination of Foley and prostaglandins versus Foley and oxytocin for cervical ripening: a network meta-analysis.

Am J Obstet Gynecol 2020 May 7. Epub 2020 May 7.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Massachusetts-Baystate, Springfield, MA. Electronic address:

Background: Trial and meta-analysis data revealed a reduction in time to delivery for Foley and prostaglandins or Foley and oxytocin vs Foley alone. However, there are limited data for the comparison of the 2 combination methods against each other.

Objective: This study aimed to determine whether Foley and prostaglandins or Foley and oxytocin decrease the time to vaginal delivery using a network meta-analysis. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.05.007DOI Listing

Invasive Group A streptococcal postpartum endometritis associated with multi-organ infarctions: an uncommon case presentation and literature review.

Postgrad Med 2020 May 7:1-6. Epub 2020 May 7.

Department of Internal Medicine, University of Alabama Huntsville Regional Campus, Huntsville, AL, USA.

: Streptococcal Toxic Shock Syndrome (STSS) is a serious condition that can arise from streptococcal postpartum endometritis. It is associated with a substantial increase in mortality rate and can rarely result in multiorgan infarction. Early recognition plays a vital role in patients' outcome. Read More

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http://dx.doi.org/10.1080/00325481.2020.1760031DOI Listing

Psammoma bodies in Papanicolaou tests and associated factors to predict an underlying malignancy: a clinicopathological analysis of 10 cases.

J Am Soc Cytopathol 2020 Apr 11. Epub 2020 Apr 11.

Department of Pathology, University of Massachusetts Medical School-Baystate Medical Center, Springfield, Massachusetts.

Introduction: Psammoma bodies (PBs) are rarely encountered in Papanicolaou tests. They have been described in benign and malignant conditions of the gynecologic tract and peritoneum. The aim of our study was to reveal the associated factors with PBs in Papanicolaou tests to predict an underlying malignancy, particularly in the absence of atypical glandular cells (AGCs). Read More

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http://dx.doi.org/10.1016/j.jasc.2020.04.002DOI Listing

Increased risk of endometriosis in patients with endometritis - a nationwide cohort study involving 84,150 individuals.

Ginekol Pol 2020 ;91(4):193-200

Department of Obstetrics and Gynecology, China Medical University Hospital, Taichung, Taiwan.

Objectives: To evaluate the incidence of endometriosis among endometritis patients and its association with confounding comorbidities.

Material And Methods: A population-based, retrospective cohort study of women aged between 20 to 55 years, who were newly diagnosed with endometritis between 2000 to 2013. A total of 16,830 endometritis patients and 67,230 non-endometritis individuals were enrolled by accessing data from the National Health Insurance Research Database of Taiwan. Read More

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http://dx.doi.org/10.5603/GP.2020.0040DOI Listing
January 2020