7,722 results match your criteria Endolymphatic Hydrops


Stability of Endolymphatic Hydrops in Ménière Disease Shown by 3-Tesla Magnetic Resonance Imaging During and After Vertigo Attacks.

JAMA Otolaryngol Head Neck Surg 2019 Apr 18. Epub 2019 Apr 18.

Department of Otolaryngology, University of Tokushima School of Medicine, Tokushima, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamaoto.2019.0435DOI Listing

Therapeutic strategies in the treatment of Menière's disease: the Italian experience.

Eur Arch Otorhinolaryngol 2019 Apr 11. Epub 2019 Apr 11.

UOSD "Vestibologia E Otorinolaringoiatria" Presidio Ospedaliero "Giovanni Paolo II", Policoro, Italy.

Purpose: Ménière's disease (MD) is an inner ear disorder of unknown etiology, whose pathological substrate is the endolymphatic hydrops. Different treatments have been proposed; however, evidence of their effectiveness is lacking. The aim of this study was to evaluate by a questionnaire which medical and surgical treatments are used in Italy for the treatment of MD and to compare them with those proposed in other countries. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00405-019-05423-7DOI Listing
April 2019
2 Reads

Menière's Disease and Disorders of the Carbohydrate Metabolism Involving the Inner Ear.

Int Arch Otorhinolaryngol 2019 Apr 15;23(2):218-220. Epub 2019 Feb 15.

Department of Otolaryngology, Hospital Albert Einstein, São Paulo, SP, Brazil.

 Menière's disease was described in 1861, but there are still uncertainties regarding its pathophysiology and treatment. Endolymphatic hydrops is recognized as a fundamental pathological characteristic of the disease, as a result of an inadequate absorption of the endolymph. A milder type of endolymphatic hydrops results from an altered chemical composition of the endolymph, due to disorders of the carbohydrate metabolism. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0038-1673698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449135PMC

Imaging of Temporal Bone.

Adv Otorhinolaryngol 2019 15;82:12-31. Epub 2019 Jan 15.

Multidetector computed tomography has been the benchmark for visualizing bony changes of the ear, but has recently been challenged by cone-beam computed tomography. In both methods, all inner ear bony structures can be visualized satisfactorily with 2D or 3D imaging. Both methods produce ionizing radiation and induce adverse health effects, especially among children. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000490268DOI Listing
January 2019
3 Reads

MRI of endolymphatic hydrops in patients with vestibular schwannomas: a case-controlled study using non-enhanced T2-weighted images at 3 Teslas.

Eur Arch Otorhinolaryngol 2019 Mar 27. Epub 2019 Mar 27.

Service de Radiologie 1, Hôpitaux Universitaires de Strasbourg, Hôpital de Hautepierre, 1 avenue Molière, 67098, Strasbourg CEDEX, France.

Objective: Vestibular schwannomas (VS) may present with similar symptoms endolymphatic hydrops. Association between hydrops and internal auditory canal VS has been described by Naganawa et al. (Neuroradiology 53:1009-1015, 2011), but has never been confirmed since. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00405-019-05395-8DOI Listing

The Natural History of Labyrinthine Hemorrhage in Patients With Sudden Sensorineural Hearing Loss.

Ear Nose Throat J 2019 Mar 26:145561319834862. Epub 2019 Mar 26.

1 Department of Otorhinolaryngology Head and Neck Surgery, First Affiliated Hospital of Fujian Medical University, Taijiang District, Fuzhou, China.

To investigate the application of inner ear 3-dimensional fluid-attenuated inversion recovery (3D-FLAIR) magnetic resonance imaging (MRI) in patients with sudden sensorineural hearing loss (SSNHL) accompanied by inner ear hemorrhage. A total of 1252 SSNHL patients who were admitted from January 2010 to April 2018 were included in the study. The patients' clinical features, complete blood counts, coagulation profiles, audiometry data, and MRI scans were retrospectively reviewed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0145561319834862DOI Listing

3D-real IR MRI detects serendipity of inner ear in enlarged vestibular aqueduct syndrome.

Acta Otolaryngol 2019 Mar 18:1-5. Epub 2019 Mar 18.

a NHC Key Laboratory of Hearing Medicine , Fudan University , Shanghai , PR China.

Background: Although, the diagnostic criteria for enlarged vestibular aqueduct syndrome (EVAS) were determined by years. On the shoulders of predecessors, we still detected some new discoveries about EVAS by using 3D-real IR MRI.

Aims/objectives: To analyze the signal intensity of membranous and osseous labyrinths of vestibular aqueduct (VA) and endolymphatic sac (ES) in EVAS using three-dimensional real inversion recovery (3D-Real-IR) magnetic resonance imaging (MRI) after intratympanic injection of gadolinium. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/00016489.2018.1563719DOI Listing
March 2019
1 Read

Clinical Features of Ears With Otosclerosis and Endolymphatic Hydrops.

Otol Neurotol 2019 Apr;40(4):441-445

Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Objective: Endolymphatic hydrops (EH) has been reported in ears with otosclerosis. The objective of this study was to investigate the clinical features of ears with otosclerosis and EH on magnetic resonance imaging (MRI) and identify predictors for the presence of EH.

Study Design: Retrospective study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MAO.0000000000002175DOI Listing
April 2019
5 Reads

Increased signal intensity of low-concentration gadolinium contrast agent by longer repetition time in heavily T-weighted-3D-FLAIR.

Jpn J Radiol 2019 Mar 12. Epub 2019 Mar 12.

Department of Radiology, Graduate School of Medicine, Nagoya University, Nagoya, Aichi, 466-8550, Japan.

Purpose: To apply for detecting low-concentration gadolinium contrast agent (Gd), such as those in the perilymph and cerebrospinal fluid (CSF) at 4 h after intravenous administrations (IV), we tried to clarify the degree of increased signal intensity (SI) of low-concentration Gd by longer repetition time (TR) in heavily T-weighed 3D-FLAIR.

Materials And Methods: A phantom was designed using Gd diluted with saline at 0.250-0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11604-019-00828-0DOI Listing

[Acoustic absorbance characteristics of wideband tympanometry in patients with Meniere's disease].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Mar;33(3):224-227

Department of Otolaryngology Head and Neck Surgery, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine; Institute of Ophthalmology, School of Medicine, Shanghai Jiaotong University; Shanghai key Laboratory of Ear and Nose Disease Transformation, Shanghai, 200092, China.

To study acoustic absorbance characteristics of wideband tympanometry in patients with unilateral Meniere's disease. Acoustic absorbance were detected using wideband tympanometry in 36 patients with unilateral Meniere's disease and 39 control subjects excluding inner ear and middle ear disease. All patients with Meniere's disease underwent electrocochleography, gadolinium contrast internal auditory canal MRI, pure tone test. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.13201/j.issn.1001-1781.2019.03.010DOI Listing

[The critical thoughts on clinical diagnosis and treatment of Meniere's disease].

Authors:
C F Dai X Y Li

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Mar;33(3):196-199

View Article

Download full-text PDF

Source
http://dx.doi.org/10.13201/j.issn.1001-1781.2019.03.002DOI Listing
March 2019
5 Reads

The role of magnetic resonance imaging in Ménière disease: the current state of endolymphatic hydrops evaluation.

Einstein (Sao Paulo) 2019 Feb 25;17(1):eMD4743. Epub 2019 Feb 25.

Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.

Technical advances in magnetic resonance imaging have allowed to accurately detect and grade endolymphatic space distension in Ménière disease; this was only possible in post-mortem histological studies until a few years ago. Magnetic resonance imaging rules out other causes of vertigo and hearing loss, and is able to evaluate the cochlear and vestibular compartments of the endolymphatic space using a dedicated protocol. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31744/einstein_journal/2019MD4743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388723PMC
February 2019
2 Reads

Three-Dimensional Magnetic Resonance Imaging Reveals the Relationship Between the Control of Vertigo and Decreases in Endolymphatic Hydrops After Endolymphatic Sac Drainage With Steroids for Meniere's Disease.

Front Neurol 2019 4;10:46. Epub 2019 Feb 4.

Department of Otolaryngology- Head and Neck Surgery, Nara Medical University, Kashihara, Japan.

Meniere's disease is a common disease, that presents with recurrent vertigo and cochlear symptoms. The pathology of Meniere's disease was first reported to involve endolymphatic hydrops in 1938. The endolymphatic sac is thought to have a role to keep the hydrostatic pressure and endolymph homeostasis for the inner ear. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fneur.2019.00046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369164PMC
February 2019
14 Reads

Sensorineural hearing loss in patients with vestibular schwannoma correlates with the presence of utricular hydrops as diagnosed on heavily T2-weighted MRI.

Diagn Interv Imaging 2019 Feb 14. Epub 2019 Feb 14.

Department of Neuroradiology, Rouen University Hospital, 76000 Rouen, France; Department of Neuroradiology and MRI, Grenoble Alpes University Hospital, SFR RMN neurosciences, 38000 Grenoble, France.

Purpose: The purpose of this study was to assess whether the volume of the vestibular endolymphatic space correlates with the degree of hearing loss using heavily T2-weighted fast imaging employing steady-state acquisition with cycle phase (FIESTA-C) MRI.

Materials And Methods: A total of 23 patients with vestibular schwannoma, as diagnosed on typical image findings, who underwent FIESTA-C MRI were included. There were 13 women and 10 men with a mean age of 63. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.diii.2019.01.006DOI Listing
February 2019

[Magnetic resonance imaging study of endolymphatic hydrops based on 3D-FLAIR sequence after single-dose intravenous gadolinium injection].

Zhonghua Yi Xue Za Zhi 2019 Jan;99(5):333-337

Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.

To investigate the visualization of endolymph in patients with otogenic vertigo by intravenous administration of single dose of gadolinium contrast agents and magnetic resonance three-dimensional fluid-attenuated inversion recovery sequence (3D-FLAIR MRI), and further assess the extent of endolymphatic hydrops. From Beijing Tongren Hospital of Capital Medical University between October 2017 and June 2018, 30 patients (16 males, 14 females) with unilateral otogenic vertigo were involved in this study, with the age of 30 to 68 years, mean age of (53±10) years. Eight hours after intravenous administration of single dose (0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.05.003DOI Listing
January 2019

The Biomechanics of Lesion Formation in Endolymphatic Hydrops: Single and Double Hit Mechanisms.

Authors:
Daniel J Pender

Otol Neurotol 2019 Mar;40(3):398-403

College of Physicians and Surgeons, Columbia University, New York City, New York.

Background: The vestibular membranes of the cochlea and saccule are subject to two simultaneous constraints as they deform in endolymphatic hydrops. Boundary tethers impose a bulge-type constraint during pressure-induced transverse membrane displacement, while inherent elasticity imposes a stretch-type constraint during stress-induced longitudinal membrane distention.

Objective: The aim of this study is to reconcile the effect of these dual constraints on membrane deformation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MAO.0000000000002149DOI Listing

Drop attacks, hydrops severity, and disease duration in hydropic ear disease (Menière's).

Authors:
Robert Gürkov

Eur Arch Otorhinolaryngol 2019 05 9;276(5):1553. Epub 2019 Feb 9.

Department of Otorhinolaryngology, Klinikum Bielefeld, Academic Teaching Hospital of the University of Münster, Teutoburger Str. 50, 33604, Bielefeld, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00405-019-05329-4DOI Listing

[The subjective perception of the vertical-a valuable parameter for determination of peripheral vestibular disorder in Menière's disease in the chronic phase?]

HNO 2019 Apr;67(4):282-292

Klinik für Hals‑, Nasen- und Ohrenheilkunde, Campus Charité Mitte, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität, Berlin Humboldt Universität zu Berlin and Berlin Institute of Health, Berlin, Deutschland.

The perception of verticality is mainly based on utricular afferent signals and central processing of the transmitted signals. However, there are also extracranial receptors that make a considerable contribution to the perception of verticality. With the subjective visual vertical (SVV) for the utricle and the subjective trunk vertical (STV), two different parameters are available that are not fully understood in terms of their response to physiologic and pathologic changes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00106-019-0626-6DOI Listing

The value of four stage vestibular hydrops grading and asymmetric perilymphatic enhancement in the diagnosis of Menière's disease on MRI.

Neuroradiology 2019 Apr 5;61(4):421-429. Epub 2019 Feb 5.

Department of Radiology, GZA Hospitals Antwerp, Oosterveldlaan 24, 2610, Wilrijk, Belgium.

Purpose: There is still a clinical-radiologic discrepancy in patients with Menière's disease (MD). Therefore, the purpose of this study was to investigate the reliability of current MRI endolymphatic hydrops (EH) criteria according to Baráth in a larger study population and the clinical utility of new imaging signs such as a supplementary fourth low-grade vestibular EH and the degree of perilymphatic enhancement (PE) in patients with Menière's disease (MD).

Methods: This retrospective study included 148 patients with probable or definite MD according to the 2015 American Academy of Otolaryngology, Head and Neck Surgery criteria who underwent a 4-h delayed intravenous Gd-enhanced 3D-FLAIR MRI between January 2015 and December 2016. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00234-019-02155-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431299PMC
April 2019
17 Reads

Quantitative evaluation of endolymphatic hydrops with MRI through intravenous gadolinium administration and VEMP in unilateral definite Meniere's disease.

Eur Arch Otorhinolaryngol 2019 Apr 29;276(4):993-1000. Epub 2019 Jan 29.

NHC Key Laboratory of Hearing Medicine, Department of Otolaryngology, Eye Ear Nose & Throat Hospital Shanghai, Fudan University, 83 Fenyang Rd, Shanghai, 200031, People's Republic of China.

Purpose: To help clinicians to further understand the significance of vestibular-evoked myogenic potential (VEMP) examinations to diagnose MD and the quantitative relationship between VEMP and MRI in assessing the location and degree of endolymphatic hydrops (EH) in definite Meniere's disease (MD) patients.

Methods: Fifty-six patients with unilateral definite MD participated in this study, which used MRIs through intravenous gadolinium administration (IV-Gd), audiometry, caloric tests and VEMP tests. The VEMP results of 26 healthy volunteers were used as a normal reference value. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00405-018-05267-7DOI Listing

Vincamine exerts protective effect on spiral ganglion neurons in endolymphatic hydrops guinea pig models.

Am J Transl Res 2018 15;10(11):3650-3663. Epub 2018 Nov 15.

Shanghai University of TCM Shanghai 201203, China.

The aim of this study was to investigate the protective effects of vincamine in endolymphatic hydrops (ELH). After ELH guinea pigs treated by vincamine, the concentration of VAP in plasma, and the levels of cAMP, MDA, SOD, GSH-Px in right cochlea were measured using spectrophotometric method. The V2R, NMDAR1, p-NMDAR1, AQP2, p-AQP2, caspase3/9 and c-caspase3/9 expressions in right cochlea were detected using western blot analysis. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291722PMC
November 2018
20 Reads

Postoperative compensation after neurotomy in Meniere's disease: Retrospective study of 15 cases.

Neurochirurgie 2019 Feb 16;65(1):20-26. Epub 2019 Jan 16.

Service de neurochirurgie, CHU de Limoges, 87000 Limoges, France. Electronic address:

Introduction: Vestibular neurotomy is a functional surgery for Meniere's disease in the event of medical treatment failure. The aim of the study was to assess the efficacy and complications of vestibular neurotomy, and to address the question of postoperative compensation.

Material And Method: All patients included in this retrospective study underwent a vestibular neurotomy at our center between 2009 and 2016. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuchi.2018.11.002DOI Listing
February 2019
7 Reads

[Transient unilateral sudden hearing loss after spinal anesthesia].

Agri 2019 Jan;31(1):50-52

Department of Anesthesiology and Reanimation, Ordu State Hospital, Ordu,Turkey.

Hearing loss after spinal anesthesia is one of the rare complications. It has been suggested that low frequent hearing loss develops after the development of endolymphatic hydrops in the cochlea due to CSF escape after dural puncture. Hearing loss after nonotologic surgical procedures is very rare and usually can only be determined by audiometric evaluation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5505/agri.2017.17136DOI Listing
January 2019
2 Reads

Clinical features and management of Meniere's disease patients with drop attacks.

Eur Arch Otorhinolaryngol 2019 Mar 2;276(3):665-672. Epub 2019 Jan 2.

Department of Otology and Skull Base Surgery, Hearing Research Key Lab of Health Ministry of China, Eye and Ear Nose and Throat Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.

Purpose: The aims of the present study are to investigate the variations in clinical features, including medical history, hearing function, vestibular function, and degree of endolymphatic hydrops (EH), in Meniere's disease (MD) patients with and without drop attacks (DAs), and to examine the efficacy of intratympanic gentamicin (ITG) treatment in alleviating DAs.

Methods: In total, 177 unilateral definite MD patients, including 16 patients with DAs and 161 patients without DAs, were enrolled. The results of hearing test, vestibular-evoked myogenic potentials (VEMPs), and magnetic resonance imaging (MRI) were analyzed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00405-018-5260-5DOI Listing

Gadolinium-enhanced MRI reveals dynamic development of endolymphatic hydrops in Ménière's disease.

Braz J Otorhinolaryngol 2018 Dec 20. Epub 2018 Dec 20.

Shanghai East Hospital, Department of Otorhinolaryngology Shanghai, Shanghai, China.

Introduction: Meniere's disease is associated with impaired hearing, tinnitus, vertigo, and aural fullness. Many anatomical studies have suggested idiopathic endolymphatic hydrops as the pathological basis of Meniere's disease, which now can be visualized by using gadolinium -enhanced magnetic resonance imaging of the inner ear.

Objective: To investigate the development of endolymphatic hydrops in Meniere's disease by monitoring the vestibules and cochleae of affected patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bjorl.2018.10.014DOI Listing
December 2018
6 Reads

Restriction of salt, caffeine and alcohol intake for the treatment of Ménière's disease or syndrome.

Cochrane Database Syst Rev 2018 12 31;12:CD012173. Epub 2018 Dec 31.

Ear Institute, Faculty of Brain Sciences, University College London, London, UK.

Background: Ménière's disease or syndrome is a chronic inner ear disorder that results in sporadic attacks of vertigo, sensorineural hearing loss, aural fullness and tinnitus.There is no definitive treatment for Ménière's disease and treatment options range from dietary modification through medication to surgery.Modification of diet, including restriction of salt, caffeine and alcohol intake, is a management option that is widely recommended to patients with Ménière's as a first-line treatment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/14651858.CD012173.pub2DOI Listing
December 2018
3 Reads

[Recent immunology research of Meniere's disease].

Authors:
S Y Guo Y Zhang B Liu

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;53(12):953-956

Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing Institute of Otorhinolaryngology, Key Laboratory of Otolaryngology Head and Neck Surgery (Capital Medical University), Ministry of Education , Beijing 100730, China.

Inner ear disease is characterized by tinnitus, deafness and vertigo. The pathogenesis remains unknown. In the past, it is considered to be related to vascular disease such as thrombus and hemadostenosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.issn.1673-0860.2018.12.017DOI Listing
December 2018

[Optimization of delivering minimum Gd-DTPA at the posterior upper point on tympanic medial wall and hT2W-3D-FLAIR sequence for detecting endolymphatic hydrops].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;53(12):931-938

Department of Otorhinolaryngology Head and Neck Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, China.

To optimize delivery of gadolinium-diethylenetriamine pentaacetic acid(Gd-DTPA) at the posterior upper point on tympanic medial wall and heavily T2-weighted 3-dimensional fluid-attenuated inversion recovery (hT2W-3D-FLAIR) sequence, and to implement the technique of detecting endolymphatic hydrops using gadolinium-enhancement MRI. Thirteen patients with periphery vertigo, who visited Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Changhai Hospital during June and December of 2017, were enrolled in the study.0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.issn.1673-0860.2018.12.011DOI Listing
December 2018

[Study on the shift of ocular vestibular evoked myogenic potentials frequency tuning of Meniere's disease].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;53(12):904-908

Department of Otorhinolaryngology, Aerospace Center Hospital, Beijing 100049, China.

To study the shift of oVEMP frequency tuning of unilateral Meniere's disease, by analyzing oVEMP of air-conducted tone bursts in various frequencies. From May 2016 to October 2017, 33 patients with unilateral Meniere's from Aerospace Center Hospital were tested for oVEMP in 500 Hz and 1 000 Hz air-conducted tone bursts respectively, and 20 healthy subjects(40 ears), matched for age and sex, were used as healthy control. The amplitudes of the N1-P1 wave and the frequency amplitude ratios of 500/1 000 Hz in affected ears, unaffected ears and normal ears were compared; and receiver operating characteristic curve was analyzed for frequency amplitude ratios of 500/1 000 Hz. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.issn.1673-0860.2018.12.006DOI Listing
December 2018

Clinical Features and Endolymphatic Hydrops in Patients With MRI Evidence of Hydrops.

Ann Otol Rhinol Laryngol 2019 Apr 17;128(4):286-292. Epub 2018 Dec 17.

1 ENT Institute and Otorhinolaryngology Department, Affiliated Eye and ENT Hospital, Fudan University, Shanghai, China.

Objectives:: The purpose of this study was to investigate the correlation between grades of endolymphatic hydrops (ELH) and clinical characteristics and determine the detailed clinical characteristics of Ménière's disease (MD) patients with evidence of hydrops based on magnetic resonance imaging (MRI).

Methods:: One hundred ninety-eight MD patients (396 ears) with MRI evidence of hydrops were included. ELH grades were evaluated using the Nakashima grading standard. Read More

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/0003489418819551
Publisher Site
http://dx.doi.org/10.1177/0003489418819551DOI Listing
April 2019
15 Reads

Diagnostic Value of the Magnetic Resonance Imaging With Intratympanic Gadolinium Administration (IT-Gd MRI) Versus Audio-Vestibular Tests in Menière's Disease: IT-Gd MRI Makes the Difference.

Otol Neurotol 2019 Mar;40(3):e225-e232

Albers-Schönberg Institute for Radiology in Hamburg, Germany.

Objective: Our aim was to evaluate the validity and reliability of clinically relevant tests in the diagnosis of Menière's disease (MD) according to the criteria formulated during 2015 as well as their efficacy in detecting endolymphatic hydrops (EH). The focus was on: three-dimensional fluid-attenuated inversion recovery-SPectral Attenuated Inversion Recovery (3D-FLAIR-SPAIR) sequences using 3 Tesla magnetic resonance imaging (3T MRI) performed 24 hours after intratympanic Gadolinium injection (IT-Gd) in comparison with the functional tests pure tone audiometry (PTA), caloric test, video head impulse test (vHIT), and cervical-vestibular-evoked-myogenic-potentials (cVEMP).

Study Design: Retrospective study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MAO.0000000000002082DOI Listing
March 2019
1 Read

Association of Ménière disease with human leukocyte antigen in Taiwanese population.

Ear Nose Throat J 2018 Dec;97(12):396-402

College of Medicine, Chang Gung University, Taoyuan, Taiwan.

The etiology of Ménière disease (MD) is multifactorial; genetic factors seem to play an important role. The associations between MD and human leukocyte antigen (HLA) status have been studied previously in several populations and have shown that the HLA alleles imparting susceptibility varied. In the present study, we explored HLA status in Taiwanese patients with definitive MD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/014556131809701208DOI Listing
December 2018
9 Reads

Three-Tesla magnetic resonance imaging of the vestibular endolymphatic space: A systematic qualitative description in healthy ears.

Eur J Radiol 2018 Dec 24;109:77-82. Epub 2018 Oct 24.

Neuroradiology Unit, Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico, Milan, Italy; Postgraduate School of Radiodiagnostics, Università degli Studi di Milano, Milan, Italy; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.

Background And Purpose: A detailed knowledge of the normal Magnetic Resonance (MR) anatomy of the vestibular endolymphatic space (ES) could be useful to understand the linkage between endolymphatic hydrops (EH) and Ménière's disease (MD). Our aim was to describe the MR anatomy of the vestibular ES as depicted by MR imaging in healthy ears.

Methods: This report describes a single-center retrospective study. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0720048X183037
Publisher Site
http://dx.doi.org/10.1016/j.ejrad.2018.10.023DOI Listing
December 2018
13 Reads

Magnetic resonance-based volumetric measurement of the endolymphatic space in patients with Meniere's disease and other endolymphatic hydrops-related diseases.

Auris Nasus Larynx 2018 Nov 29. Epub 2018 Nov 29.

Department of Otorhinolaryngology Head and Neck Surgery, Nara Medical University, 840 Shijo-cho, Kashihara-city, Nara, Japan.

Objective: To employ magnetic resonance imaging (MRI) to measure the volume of the inner ear endolymphatic space (ELS) in patients with acute low-tone sensorineural hearing loss (ALHL), sudden deafness (SD), cochlear Meniere's disease (cMD), and unilateral MD (uMD) compared with control subjects (CS) with chronic rhinosinusitis.

Methods: Forty-one patients with ALHL, 82 with SD, 48 with cMD, 72 with uMD, and 47 CS participated in the study. With the exception of all uMD patients, none of the subjects had vertigo. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.anl.2018.11.008DOI Listing
November 2018
13 Reads

Change in endolymphatic hydrops 2 years after endolymphatic sac surgery evaluated by MRI.

Auris Nasus Larynx 2018 Nov 27. Epub 2018 Nov 27.

Department of Otorhinolaryngology - Head and Neck Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.

Objective: This study was performed to determine whether endolymphatic sac surgery improves vestibular and cochlear endolymphatic hydrops 2 years after sac surgery and to elucidate the relationship between the degree of improvement of endolymphatic hydrops and the changes in vertigo symptoms, the hearing level, and the summating potential/action potential ratio (-SP/AP ratio) by electrocochleography (ECochG) in patients with Ménière's disease (MD).

Methods: Twenty-one patients with unilateral MD who underwent sac surgery were included in this study. All patients underwent gadolinium-enhanced magnetic resonance imaging (Gd-MRI) before and 2 years after sac surgery. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03858146183065
Publisher Site
http://dx.doi.org/10.1016/j.anl.2018.10.011DOI Listing
November 2018
24 Reads

Bilateral delayed endolymphatic hydrops evaluated by bilateral intratympanic injection of gadodiamide with 3T-MRI.

PLoS One 2018 5;13(12):e0206891. Epub 2018 Dec 5.

Department of Otorhinolaryngology, Shinshu University School of Medicine, Matsumoto, Japan.

The purpose of this study was to assess the diagnostic performance of 3T MRI after intratympanic injection of gadodiamide for delayed endolymphatic hydrops (DEH), and assess the relationship between endolymphatic hydrops (ELH) and vestibular function in patients diagnosed with DEH and confirmed by 3T MRI. Nineteen patients clinically diagnosed with DEH (11 ipsilateral DEH, 8 contralateral DEH) participated in this study. Diluted gadodiamide was administered to the bilateral tympanic cavity by injection through the tympanic membrane. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0206891PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281314PMC
December 2018
17 Reads

Vertical head impulse and caloric are complementary but react opposite to Meniere's disease hydrops.

Laryngoscope 2018 Dec 4. Epub 2018 Dec 4.

Department of Otolaryngology, University of Tokushima School of Medicine, Tokushima, Japan.

Objectives/hypothesis: Meniere's disease (MD) patients can show normal head impulses despite poor caloric test results. This study aimed to investigate the discrepancy in the vestibulo-ocular reflex (VOR) in MD patients and whether endolymphatic hydrops (EH) influence the VOR.

Study Design: Prospective, cross-sectional observational study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/lary.27580DOI Listing
December 2018
21 Reads

Usefulness of Intravenous Gadolinium Inner Ear MR Imaging in Diagnosis of Ménière's Disease.

Sci Rep 2018 Dec 3;8(1):17562. Epub 2018 Dec 3.

Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

This study aimed to investigate the usefulness of the intravenous gadolinium enhanced inner ear magnetic resonance imaging (IV-Gd inner ear MRI) in diagnosing Ménière's disease(MD) and find a correlation between the degree of endolymphatic hydrops(EH) and the audiovestibular tests. Total 29 patients diagnosed with unilateral definite MD were enrolled. All patients underwent IV-Gd inner ear MRI and auditory and vestibular function tests such as pure tone audiometry (PTA), electrocochleography (ECoG), cervical vestibular evoked myogenic potential (cVEMP) and caloric test. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-018-35709-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277445PMC
December 2018
6 Reads

Disorders of the inner-ear balance organs and their pathways.

Handb Clin Neurol 2018 ;159:385-401

Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, Central Clinical School, University of Sydney, Sydney, NSW, Australia; Neurology Department, Royal Prince Alfred Hospital, Central Clinical School, University of Sydney, Sydney, NSW, Australia. Electronic address:

Disorders of the inner-ear balance organs can be grouped by their manner of presentation into acute, episodic, or chronic vestibular syndromes. A sudden unilateral vestibular injury produces severe vertigo, nausea, and imbalance lasting days, known as the acute vestibular syndrome (AVS). A bedside head impulse and oculomotor examination helps separate vestibular neuritis, the more common and innocuous cause of AVS, from stroke. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/B97804446391650
Publisher Site
http://dx.doi.org/10.1016/B978-0-444-63916-5.00025-2DOI Listing
March 2019
16 Reads

Secondary Endolymphatic Hydrops Associated With Spontaneous Intracranial Hypotension.

JAMA Otolaryngol Head Neck Surg 2018 Nov 21. Epub 2018 Nov 21.

Department of Otolaryngology-Head and Neck Surgery, Osaka University, Graduate School of Medicine, Osaka, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamaoto.2018.3073DOI Listing
November 2018

Imaging of Ménière Disease.

Neuroimaging Clin N Am 2019 Feb;29(1):19-28

Department of Radiology, GZA Hospitals Antwerp, Oosterveldlaan 24, Wilrijk 2610, Belgium.

Visualization of the morphologic substrate of Ménière disease, the endolymphatic hydrops, can be performed using noncontrast or contrast-enhanced MR imaging techniques. Noncontrast MR imaging uses a heavily T2-weighted sequence; however, its reproducibility remains to be confirmed. Contrast-enhanced MR imaging techniques mainly use a 3-dimensional fluid-attenuated inversion recovery sequence after intratympanic gadolinium administration or after a 4-hour delayed intravenous gadolinium administration. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nic.2018.09.002DOI Listing
February 2019
13 Reads

Gentamicin delivery to the inner ear: Does endolymphatic hydrops matter?

PLoS One 2018 15;13(11):e0207467. Epub 2018 Nov 15.

Department of Otorhinolaryngology, S.João Hospital Centre, Porto, Portugal.

Introduction: Middle ear application of gentamicin is a common medical treatment for uncontrolled Ménière's disease. The objective of the study was to evaluate the impact of endolymphatic hydrops on inner ear delivery.

Methods: Perilymph gentamicin concentrations and correlation with endolymphatic hydrops in an animal model were assessed. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0207467PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237362PMC
April 2019
18 Reads

Towards personalized medicine in Ménière's disease.

F1000Res 2018 15;7. Epub 2018 Aug 15.

Clinique du Vertige, Centre Hospitalier Emile Mayrisch, Esch-sur-Alzette, Luxembourg.

Ménière's disease (MD) represents a heterogeneous group of relatively rare disorders with three core symptoms: episodic vertigo, tinnitus, and sensorineural hearing loss involving 125 to 2,000 Hz frequencies. The majority of cases are considered sporadic, although familial aggregation has been recognized in European and Korean populations, and the search for familial MD genes has been elusive until the last few years. Detailed phenotyping and cluster analyses have found several clinical predictors for different subgroups of patients, which may indicate different mechanisms, including genetic and immune factors. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12688/f1000research.14417.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097350PMC
March 2019
13 Reads

The vestibular aqueduct sign: Magnetic resonance imaging can detect abnormalities in both ears of patients with unilateral Meniere's disease.

J Neuroradiol 2018 Nov 10. Epub 2018 Nov 10.

Department of neuroradiology and MRI, Grenoble university hospital, 38000 Grenoble France; University Grenoble Alpes, 38000 Grenoble, France; IRMaGe, inserm US 17, CNRS UMS 3552, 38000 Grenoble, France.

Background And Purpose: In patients with Meniere's disease (MD), saccular hydrops can only be studied by magnetic resonance imaging (MRI) at a late stage when the disease is already responsible for moderate to severe hearing loss. However, these patients may also present vestibular aqueduct (VA) abnormalities.

Materials And Methods: In this prospective study (38RC14. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurad.2018.10.003DOI Listing
November 2018
23 Reads

Tenotomy of the middle ear muscles : An unknown surgical approach in Meniere's disease.

Wien Klin Wochenschr 2019 Feb 12;131(3-4):87-91. Epub 2018 Nov 12.

Department of Otorhinolaryngology, Head and Neck Surgery, Rudolfstiftung Teaching Hospital, Juchgasse 25, 1030, Vienna, Austria.

Tenotomy of the tendon of the stapedius and tensor tympani muscles is a relatively unknown therapeutic procedure in Menière's disease. Widespread approaches include medicinal treatment with betahistine or diuretics as well as interventional procedures, such as intratympanic gentamicin or glucocorticoid injection, vestibular neurectomy, labyrinthectomy or endolymphatic sac surgery. The exact pathomechanism of this approach is not fully known. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00508-018-1405-1DOI Listing
February 2019
16 Reads

Signal Intensity of the Cerebrospinal Fluid after Intravenous Administration of Gadolinium-based Contrast Agents: Strong Contrast Enhancement around the Vein of Labbe.

Magn Reson Med Sci 2018 Nov 9. Epub 2018 Nov 9.

Department of Otorhinolaryngology, Kamiiida Daiichi General Hospital.

Purpose: Since the first report on the deposition of gadolinium in the brain parenchyma after repeated intravenous administrations of gadolinium-based contrast agent GBCA (IV-GBCA), the mechanisms of penetration and retention are still remaining a hot topic of discussion and a target of investigation. We routinely obtain endolymphatic hydrops (EH) images at 4 h after IV administration of a single dose (SD) of GBCA (IV-SD-GBCA) using heavily T-weighted three-dimensional fluid-attenuated inversion recovery imaging (hTW-3D-FLAIR). Occasionally, we have encountered cases, which indicate high-signal intensity (SI) in the cerebrospinal fluid (CSF) surrounding the vein of Labbe. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2463/mrms.mp.2018-0043DOI Listing
November 2018

[The effectiveness of the intra-tympanic administration of methylprednisolone and gentamycin for the treatment of Meniere's disease].

Vestn Otorinolaringol 2018;83(5):17-20

MSCh 'Neftyanik' joint stock company, Tyumen, Russia.

Meniere's disease is an inner ear pathology characterized by periodic fits of systemic dizziness, fluctuating low-frequency sensorineural loss of hearing, stuffiness in the ear and tympanophonia. The objective of the present study was to evaluate the effectiveness of the intra-tympanic administration of methyl prednisolone in the combination with gentamycin used to treat the patients presenting with Meniere's disease. The study included 18 patients at the age varying from 18 to 70 years presenting with this condition. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17116/otorino20188305117DOI Listing
January 2018
6 Reads

Evaluation of the Effects of Chronic Kidney Disease and Hemodialysis on the Inner Ear Using Multifrequency Tympanometry.

J Int Adv Otol 2018 Dec;14(3):447-450

Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Objectives: To evaluate the effects of chronic kidney disease (CKD) and hemodialysis (HD) on the inner ear using the G width (the width between the bimodal peaks of the conductance (G) tympanogram at 2,000 Hz), which reflects the inner ear pressure and/or the existence of endolymphatic hydrops.

Materials And Methods: We selected five patients (10 ears) from the patients with CKD who were hospitalized for creation of arteriovenous fistula prior to initiation of HD (non-HD group), and we selected seven patients (14 ears) from the patients with CKD who were undergoing HD (the HD group). As a control group, we selected 80 healthy individuals (160 ears); these were mainly the medical staff of the hospital. Read More

View Article

Download full-text PDF

Source
http://www.advancedotology.org/eng/makale/1267/84/Full-Text
Publisher Site
http://dx.doi.org/10.5152/iao.2018.4736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354524PMC
December 2018
10 Reads

Autoimmunity and Otolaryngology Diseases.

J Immunol Res 2018;2018:2747904. Epub 2018 Oct 4.

Department Oral and Maxillofacial Sciences, Sapienza University of Rome, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2018/2747904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193323PMC
February 2019
2 Reads

Age Dependence of Gadolinium Leakage from the Cortical Veins into the Cerebrospinal Fluid Assessed with Whole Brain 3D-real Inversion Recovery MR Imaging.

Magn Reson Med Sci 2019 Apr 5;18(2):163-169. Epub 2018 Nov 5.

Department of Radiology, Nagoya University Graduate School of Medicine.

Purpose: It has been reported that intravenously administered gadolinium-based contrast agents (IV-GBCAs) leak into the cerebrospinal fluid (CSF) even in healthy subjects. The purpose of this study was to evaluate GBCA leakage from the cortical veins in patients with delayed imaging after IV-GBCA.

Materials And Methods: There are two parts of retrospective study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2463/mrms.mp.2018-0053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460126PMC