8,180 results match your criteria Endolymphatic Hydrops


Magnetic resonance imaging of endolymphatic hydrops in patients with unilateral Meniere's disease: a comparison between with and without herniation into the posterior and lateral semi-circular canals.

Acta Otolaryngol 2021 Jun 1:1-7. Epub 2021 Jun 1.

Department of Otorhinolaryngology-Head and Neck Surgery, Nara Medical University, Nara, Japan.

Background: The presence of endolymphatic hydrops (ELH) in patients with Meniere's disease (MD) is considered a pathological hallmark.

Aims/objectives: We aimed to conduct a quantitative volumetric measurement of inner ear ELH in patients with unilateral MD (uMD). The values of uMD with and without herniation into the posterior semi-circular canal (h-PSC) and the lateral semi-circular canal (h-LSC) were compared using 3 D magnetic resonance imaging. Read More

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Evolution of migraine vertigo in overlapping syndrome with Ménière's disease: prognostic role of instrumental examination.

Acta Otorhinolaryngol Ital 2021 Apr;41(2):180-184

Istituto Euro-Mediterraneo di Scienza e Tecnologia - IEMEST, Palermo, Italy.

Introduction: Migraine vertigo (MV) and Ménière's disease (MD) share several signs and symptoms such as tinnitus, fullness, photophobia, phonophobia, headache and vertigo spells lasting hours.

Objective: The aim of the present study was to prospectively observe patients with MV with a sporadic audiological symptom evaluated with clinical examination, Vestibular Evoked Myogenic Potentials (VEMPs), ECochG and v-HIT.

Results: The finding of VEMP asymmetry, according to our cut-off of 33% of difference between sides, resulted in 20 cases, of which 6 had asymmetry of both c-VEMPs and o-VEMPS, all with development of fluctuating hearing during follow-up. Read More

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Enhanced Eye Velocity in Head Impulse Testing-A Possible Indicator of Endolymphatic Hydrops.

Front Surg 2021 7;8:666390. Epub 2021 May 7.

Vestibular Research Laboratory, School of Psychology, The University of Sydney, Sydney, NSW, Australia.

On video head impulse testing (vHIT) of semicircular canal function, some patients reliably show enhanced eye velocity and so VOR gains >1.0. Modeling and imaging indicate this could be due to endolymphatic hydrops. Read More

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[Studies of brain function associated with otogenic vertigo].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 May;56(5):517-521

Department of Otorhinolaryngology Head and Neck Surgery, Sixth People's Hospital, Shanghai Jiaotong University,Shanghai 200233, China.

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Wideband tympanometry as a diagnostic tool for Meniere's disease: a retrospective case-control study.

Eur Arch Otorhinolaryngol 2021 May 19. Epub 2021 May 19.

Department of Otolaryngology, Head and Neck Surgery and Audiology, Aalborg University Hospital, Aalborg, Denmark.

Purpose: The main purpose of this study was to investigate the usefulness of wide band tympanometry (WBT) as a diagnostic tool for Ménière's disease (MD) by comparing differences in absorbance measures between normal hearing ears and patient diagnosed with MD.

Methods: We conducted a retrospective case-control study. From a cohort of 116 patients diagnosed with Ménière disease, 52 MD patients and 99 normal hearing adults with no history of otological disease served as subjects. Read More

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Altered mapping of sound frequency to cochlear place in ears with endolymphatic hydrops provide insight into the pitch anomaly of diplacusis.

Sci Rep 2021 May 17;11(1):10380. Epub 2021 May 17.

Department of Otolaryngology, School of Medicine, Washington University St. Louis, Campus Box 8115, 660 South Euclid Avenue, Saint Louis, MO, 63110, USA.

A fundamental property of mammalian hearing is the conversion of sound pressure into a frequency-specific place of maximum vibration along the cochlear length, thereby creating a tonotopic map. The tonotopic map makes possible systematic frequency tuning across auditory-nerve fibers, which enables the brain to use pitch to separate sounds from different environmental sources and process the speech and music that connects us to people and the world. Sometimes a tone has a different pitch in the left and right ears, a perceptual anomaly known as diplacusis. Read More

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Diagnosis of Menière's disease on MRI: feasibility at 1.5 Tesla.

Acta Radiol 2021 May 17:2841851211016478. Epub 2021 May 17.

Department of Radiology, GZA Hospitals Antwerp, Wilrijk, Belgium.

Background: Menière's disease (MD) is clinically characterized by the triad sensorineural hearing loss, tinnitus and/or aural fullness, and vertigo. Endolymphatic hydrops (EH) is the histopathological basis associated with MD, which can be demonstrated on magnetic resonance imaging (MRI). Currently, most studies are done on a 3-T MRI scanner and to date it is believed that EH can only be demonstrated on a 3-T magnet. Read More

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Clinical Prevalence of Enhanced Vestibulo-Ocular Reflex Responses on Video Head Impulse Test.

Otol Neurotol 2021 May 14. Epub 2021 May 14.

Neurotology Unit, Otorhinolaryngology Department, Hospital Universitario Donostia, Donostia (San Sebastián), Spain.

Objective: To measure and analyze the clinical and epidemiological characteristics of patients and healthy controls with enhanced eye velocity responses as well as evaluate their relationship with endolymphatic hydrops related diseases.

Study Design: Cross-sectional clinical study.

Setting: Tertiary hospital. Read More

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Intravenous Delayed Gadolinium-Enhanced MR Imaging of the Endolymphatic Space: A Methodological Comparative Study.

Front Neurol 2021 22;12:647296. Epub 2021 Apr 22.

Department of Neurology, University Hospital, Ludwig-Maximilians-Universität, Munich, Germany.

non-invasive verification of endolymphatic hydrops (ELH) by means of intravenous delayed gadolinium (Gd) enhanced magnetic resonance imaging of the inner ear (iMRI) is rapidly developing into a standard clinical tool to investigate peripheral vestibulo-cochlear syndromes. In this context, methodological comparative studies providing standardization and comparability between labs seem even more important, but so far very few are available. One hundred eight participants [75 patients with Meniere's disease (MD; 55. Read More

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Magnetic resonance imaging of the inner ear in the diagnostics of Ménière's disease.

Otolaryngol Pol 2020 Dec;75(2):1-8

Department of Otorhinolaryngology, Head and Neck Surgery, Medical University of Warsaw, Poland; Head: Prof. Kazimierz Niemczyk MD PhD.

Ménière's disease is characterized by sudden episodes of vertigo accompanied by tinnitus and/or feeling of fullness in the ear as well as fluctuating sensorineural hearing loss. Despite numerous studies, the etiology of this disease remains unknown. However, the enlargement of the inner ear's endolymphatic spaces, referred to as endolymphatic hydrops, is considered the underlying condition. Read More

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December 2020

Vestibular drop attacks in Ménière's disease: A systematic review and meta-analysis of frequency, correlates and consequences.

J Vestib Res 2021 Apr 28. Epub 2021 Apr 28.

Hearing and Balance Research Unit, Field of Otolaryngology, School of Medicine, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

Background: Vestibular drop attacks (VDA), also called Tumarkin otolith crises as a complication of Ménière's disease (MD) were first described in 1936. Nevertheless, a clearer understanding of their prevalence and manifestations is needed.

The Objective: of this review is to determine the frequency, correlates and consequences of VDA in MD. Read More

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[Betahistine in vestibular disorders: current concepts and perspectives].

Vestn Otorinolaringol 2021 ;86(2):73-81

Federal Siberian Research Clinical Centre under the Federal Medical Biological Agency, Krasnoyarsk, Russia.

The goal of this paper is to review the pharmacological profile of betahistine and evidence for using it in the treatment of common vestibular disorders. Betahistine is a weak agonist for histamine H1 receptors and strong antagonist for histamine H3 receptors. It demonstrates the maximum benefit in different types of peripheral vertigo, especially in Meniere's disease. Read More

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Association between Chronic Obstructive Pulmonary Disease and Ménière's Disease: A Nested Case-Control Study Using a National Health Screening Cohort.

Int J Environ Res Public Health 2021 04 24;18(9). Epub 2021 Apr 24.

Hallym Data Science Laboratory, Hallym University College of Medicine, Anyang 14068, Korea.

This study explored the relation between Ménière's disease and chronic obstructive pulmonary disease (COPD). The ≥40-year-old population of the Korean National Health Insurance Service-Health Screening Cohort was included. In total, 7734 Ménière's disease patients and 30,936 control participants were enrolled. Read More

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[Episodic vestibular syndrome].

Ugeskr Laeger 2021 04;183(15)

Dizziness and vertigo are frequent symptoms in the primary care facility and emergency departments. Episodic vestibular syndrome (EVS) is defined as episodic dizziness, vertigo or postural imbalance with remission between episodes. EVS can be divided into spontaneous (s-EVS) and triggered EVS (t-EVS). Read More

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Cross-sectional Area of the Superior Petrosal Sinus is Reduced in Patients with Significant Endolymphatic Hydrops.

Magn Reson Med Sci 2021 Apr 24. Epub 2021 Apr 24.

Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine.

Purpose: To evaluate the relationship between the size of the venous structures related to the inner ear and the degree of endolymphatic hydrops (EH).

Methods: Thirty-four patients with a suspicion of EH underwent whole brain MR imaging including the inner ear. Images were obtained pre- and post-administration, and at 4 and 24 hours after the intravenous administration of a gadolinium-based contrast agent (IV-GBCA). Read More

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MR Imaging of Endolymphatic Hydrops in Five Minutes.

Magn Reson Med Sci 2021 Apr 24. Epub 2021 Apr 24.

Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine.

In this study, we present images acquired by a fast-imaging method for the evaluation of endolymphatic hydrops after intravenous administration of a single dose of gadolinium-based contrast agent. We utilized the hybrid of reversed image of MR cisternography and a positive perilymph signal by heavily T2- weighted 3D-fluid attenuated inversion recovery-multiplied by T2 (HYDROPS2-Mi2) method combined with deep learning reconstruction denoising. The scan time for the fast protocol was approximately 5 mins, which is far shorter than previously reported scan times. Read More

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Endolymphatic Sac Surgery And Posterior Semicircular Canal Fenestration For Meniere's Disease.

Pril (Makedon Akad Nauk Umet Odd Med Nauki) 2021 Apr 23;42(1):141-148. Epub 2021 Apr 23.

University Clinic for Otorhinolaryngology, Faculty of Medicine, University Ss. Cyril and Methodius, Skopje, RN Macedonia.

: To evaluate the efficiency and safety of the simultaneous endolymphatic sac drainage (ELSD) and posterior semicircular canal fenestration (PSCF) primary on the vestibular function as an new therapeutic strategy in the patients with medically refractory Meniere's disease (MD).: retrospective follow-up study.: University Clinic of Otolaryngology. Read More

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Prosper Menière: the man who located vertigo in the inner ear.

Arq Neuropsiquiatr 2021 03;79(3):254-256

Hospital Naval Marcílio Dias, Rio de Janeiro RJ, Brazil.

Since the Greek Aellus Galenum (129 AD - c.200/c.216), vertigo was considered a problem attributed to a cerebral disorder, diagnosed as the manifestation of apoplectiform cerebral congestion. Read More

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Volume quantification of endolymphatic hydrops in patients with vestibular schwannoma.

Neuroimage Clin 2021 3;30:102656. Epub 2021 Apr 3.

Department of Otolaryngology-Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yishan Road, Shanghai 200233, China; Otolaryngology Institute of Shanghai Jiao Tong University, Shanghai 200233, China; Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai 200233, China.

Objective: The origin of vestibular symptoms in patients with vestibular schwannoma (VS) is uncertain. We used intratympanic gadolinium-enhanced magnetic resonance imaging (MRI) to confirm the labyrinthine lesions in patients with VS and to explore the features of endolymphatic hydrops (EH) in these patients.

Methods: In total, 66 patients diagnosed with unilateral VS were enrolled in this study and underwent intratympanic gadolinium-enhanced MRI. Read More

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Correlation between magnetic resonance imaging classification of endolymphatic hydrops and clinical manifestations and audiovestibular test results in patients with definite Ménière's disease.

Auris Nasus Larynx 2021 Apr 14. Epub 2021 Apr 14.

Department of Otorhinolaryngology, Head and Neck Surgery, Medical University of Warsaw, Poland.

Objectives: The purpose was to evaluate magnetic resonance imaging (MRI) classification of endolymphatic hydrops with clinical features, audiological and vestibular tests in patients with definite unilateral Ménière's disease (MD).

Methods: Thirty-eight patients were enrolled in this study. The severity of the main clinical symptoms, audiovestibular tests, and MRI, performed 4 hours after intravenous injection of gadobutrol to visualize inner ear compartments, were evaluated. Read More

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The Correlation of Clinical Features and Endolymphatic Hydrops Visualized by 3D-Real IR MRI in Children With Sudden Sensorineural Hearing Loss.

Ear Nose Throat J 2021 Apr 13:1455613211009432. Epub 2021 Apr 13.

Department of Radiology, Eye & ENT Hospital of Fudan University, Shanghai, China.

Objectives: To investigate the correlation between clinical features and endolymphatic hydrops (EH) in children with sudden sensorineural hearing loss (SSNHL).

Methods: We collected 30 SSNHL children aged ≤17 years old, all of whom underwent intravenous gadolinium injection. After 4 hours, inner ear 3-dimensional inversion recovery sequence with real reconstruction (3D-real IR) magnetic resonance imaging was performed. Read More

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Effectiveness of intratympanic dexamethasone for the treatment of vertigo attacks in patients with Ménière's disease compared with betahistine pharmacotherapy.

J Int Med Res 2021 Apr;49(4):300060520985647

37637Semmelweis University, Department of Otolaryngology and Head and Neck Surgery, Budapest, Hungary.

Objective: This study analyzed the possible effects of intratympanic steroid (ITS) therapy in the symptomatic treatment of vertigo attacks in patients with Ménière's disease.

Methods: Thirty-five patients treated with ITS (dexamethasone) plus betahistine (Group A) and 35 patients treated with betahistine alone (Group B) were enrolled in this investigation. Complaints were analyzed using medical records and vertigo diaries. Read More

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The neurologist and the hydrops.

J Vestib Res 2021 Apr 9. Epub 2021 Apr 9.

Department of Evaluation and Treatment of Pain, FHU INOVPAIN, CHU Timone, AP-HM, Marseille, France.

The presence of endolymphatic hydrops has been studied in many neurological disorders. The pathophysiological mechanisms may involve CSF pressure variations, transmitted to the innear ear. This hydrops could play a role in vestibular or cochlear symptoms. Read More

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Case Report: Positive Pressure Therapy Combined With Endolymphatic sac Surgery in a Patient With Ménière's Disease.

Front Surg 2021 25;8:606100. Epub 2021 Mar 25.

Department of Otolaryngology, University of Tokushima School of Medicine, Tokushima, Japan.

Positive pressure therapy (PPT) is applied for medically-intractable vertigo in Ménière's disease (MD); however, it remains unknown whether PPT affects endolymphatic hydrops (EH). In this case report, we describe a 5-year course of MD in a patient in which EH was repeatedly observed. As the patient experienced recurrent vertigo attacks after endolymphatic sac surgery, he began to use the PPT device additionally and vertiginous episodes decreased in accordance with a decrease in the EH volume. Read More

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Comparison of inner ear MRI enhancement in patients with Meniere's disease after intravenous injection of gadobutrol, gadoterate meglumine, or gadodiamide.

Eur J Radiol 2021 Jun 26;139:109682. Epub 2021 Mar 26.

Department of Radiology, The First Hospital of China Medical University, Shenyang, Liaoning 110001, China. Electronic address:

Purpose: To compare the enhancement results of three gadolinium contrast agents in the inner ear of patients with Meniere's disease 4 h after intravenous injection of gadobutrol, gadoterate meglumine, or gadodiamide.

Methods: We enrolled 60 patients with a definitive diagnosis of unilateral Meniere's disease and divided them into three groups of 20 patients; each group received a double dose of gadobutrol, gadoterate meglumine, or gadodiamide. The postcontrast signal intensity of the basal cochlear turn was scored quantitatively, and qualitative visual evaluation of the cochlea, vestibule and semi-circular canals was also performed. Read More

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The relationship between clinical characteristics and magnetic resonance imaging results of Ménière disease: a prospective study.

Sci Rep 2021 Mar 30;11(1):7212. Epub 2021 Mar 30.

Department of Otolaryngology, Head and Neck Surgery & Audiology and Neurotology, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden.

Ménière disease (MD) is an idiopathic inner ear disorder, and endolymphatic hydrops (EH) being considered to be its pathological basis. Currently, there is no gold standard for diagnosing MD. Previous study has reported visualized EH using MRI by intratympanic gadolinium-based contrast media (GBCM) administration (IT-Gd) in patients with MD, and this technique was gradually established for MD diagnosis. Read More

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Identification of early-stage Meniere's disease as a cause of unilateral tinnitus.

Authors:
Haider Alsarhan

J Otol 2021 Apr 11;16(2):85-88. Epub 2020 Nov 11.

College of Medicine Mustansiriyah University, Al-Qadesiyah-Alkarkh, Baghdad, 00616, Iraq.

Introduction: Meniere's disease (MD) is characterized by episodic symptoms, including vertigo, hearing loss, and tinnitus.

Objectives: in this study, cases of unilateral tinnitus were investigated for MD.

Method: Twenty-two patients who presented with chronic unilateral tinnitus on puretone audiograms showing an average threshold better than 25 dB HL and thresholds in the lower frequencies worse than those in the higher frequencies by more than 10 dB were suspected to have early-stage MD and underwent electrocochleography (ECochG). Read More

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Endolymphatic Hydrops in Patients With Vestibular Migraine and Concurrent Meniere's Disease.

Front Neurol 2021 11;12:594481. Epub 2021 Mar 11.

Department of Neurology, University Hospital, Ludwig-Maximilians-Universität, Munich, Germany.

Intravenous contrast agent enhanced, high-resolution magnetic resonance imaging of the inner ear (iMRI) confirmed that patients with Menière's disease (MD) and vestibular migraine (VM) could present with endolymphatic hydrops (EH). The present study aimed to investigate EH characteristics and their interrelation to neurotologic testing in patients with VM, MD, or VM with concurrent MD (VM-MD). Sixty-two patients (45 females, aged 23-81 years) with definite or probable VM ( = 25, 19 definite), MD ( = 29, 17 definite), or showing characteristics of both diseases ( = 8) were included in this study. Read More

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The relationship between nutrition and Ménière's disease.

Auris Nasus Larynx 2021 Mar 24. Epub 2021 Mar 24.

Department of Audiology, Faculty of Health Sciences, Marmara University, Istanbul, Turkey. Electronic address:

Ménière's disease is an inner ear disease with attacks characterized by ear fullness, tinnitus, fluctuant sensorineural hearing loss and vertigo. Although pathophysiology of the disease is not fully known, endolymphatic hydrops are believed to play a role. Although there is no certain treatment procedure for Ménière's disease, some treatments are applied to prevent attacks, to treat the symptoms that occur during the attacks, and to prevent the permanent effects of the symptoms on the hearing and balance system. Read More

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Vertigo without cochlear symptoms: vestibular migraine or Menière disease?

Neurol Sci 2021 Mar 25. Epub 2021 Mar 25.

Department of Otolaryngology Head & Neck Surgery, IRCCS San Raffaele Scientific Institute, San Raffaele Hospital, Via Olgettina 60, 20132, Milan, Italy.

Background: Menière's disease (MD) is an inner ear disorder due to raised endolymphatic pressure (hydrops), characterized by cochlear symptoms associated with episodic vertigo. In delayed hydrops, vertigo attacks begin long after the onset of a hearing loss. Few were published on MD in which the onset of vertigo precedes cochlear symptoms by several months. Read More

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