1,018 results match your criteria Endocrinologia y Nutricion [Journal]


Endocrinology, diabetes and nutrition: The future is here.

Endocrinol Nutr 2016 Dec;63(10):509-510

En representación de la Sociedad Española de Endocrinología y Nutrición.

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http://dx.doi.org/10.1016/j.endonu.2016.10.001DOI Listing
December 2016
9 Reads

Healthcare costs of people with type 2 diabetes mellitus in the Basque Country (Spain).

Endocrinol Nutr 2016 Dec 4;63(10):543-550. Epub 2016 Nov 4.

Osakidetza, Servicio Vasco de Salud, Vitoria-Gasteiz, España; Universidad del País Vasco, Leioa, España; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, España.

Objective: The aim of the study was to estimate the direct costs of healthcare provided to patients with type 2 diabetes mellitus (T2DM) in the Basque Country and to compare them with those of the population with chronic diseases.

Material And Methods: A retrospective, cross-sectional, population-based study. Direct healthcare costs for patients aged over 35 years diagnosed with T2DM in the Basque Country (n=126,894) were calculated, stratified by age, sex and deprivation index, and compared to the costs for the population diagnosed with a chronic disease other than T2DM (n=1,347,043). Read More

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http://dx.doi.org/10.1016/j.endonu.2016.08.003DOI Listing
December 2016
11 Reads

Impact of diabetes education on type 1 diabetes mellitus control in children.

Endocrinol Nutr 2016 Dec 17;63(10):536-542. Epub 2016 Oct 17.

Servicio de Pediatría, Unidad de Diabetes Pediátrica, Hospital Universitario Ramón y Cajal, Madrid, España.

Introduction: Diabetes education is an essential tool to achieve treatment objectives in type1 diabetes mellitus (T1DM). The aim of this study was to determine if understanding of diabetes by caregivers/patients or sociodemographic factors affect blood glucose control in children and adolescents with T1DM.

Patients And Methods: The level of knowledge of 105 caregivers of children and adolescents with T1DM was assessed using a survey adapted to the type of treatment used (multiple dose insulin [MDI] or continuous subcutaneous insulin infusion [CSII]). Read More

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http://dx.doi.org/10.1016/j.endonu.2016.08.004DOI Listing
December 2016
9 Reads

Bariatric surgery results in patients with type 1 diabetes mellitus on continuous subcutaneous insulin infusion therapy.

Endocrinol Nutr 2016 Dec 17;63(10):571-572. Epub 2016 Oct 17.

Department of Endocrinology and Nutrition, Santa Creu i Sant Pau Hospital, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.endonu.2016.09.002DOI Listing
December 2016
15 Reads

Venlafaxine drug interaction in the diagnosis of pheochromocytoma.

Endocrinol Nutr 2016 Dec 15;63(10):569-570. Epub 2016 Oct 15.

Servicio de Endocrinología y Nutrición, Hospital HM Montepríncipe, Boadilla del Monte, Madrid, España.

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http://dx.doi.org/10.1016/j.endonu.2016.08.006DOI Listing
December 2016
19 Reads

Cardiovascular risk factors in scholars (RIVACANGAS).

Endocrinol Nutr 2016 Dec 13;63(10):511-518. Epub 2016 Oct 13.

Sección de Endocrinología Pediátrica, Hospital Universitario de Cruces. CIBERDEM, Barakaldo, Bizkaia, España.

Background And Aim: The current guidelines for treatment of high blood pressure do not include any section dedicated to hypertension in children and adolescents or to cardiovascular disease (CVD) prevention strategies in that age group. Our study was aimed at identifying cardiovascular risk factors (CVRFs) in an adolescent sample.

Subjects And Methods: A cross-sectional study of a sample of adolescents aged 12 to 17years (n=630), conducted from October 2014 to February 2015 in four schools in Cangas do Morrazo (Pontevedra). Read More

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http://dx.doi.org/10.1016/j.endonu.2016.07.005DOI Listing
December 2016
13 Reads

Impact of obesity on bone metabolism.

Endocrinol Nutr 2016 Dec 12;63(10):551-559. Epub 2016 Oct 12.

Servicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, Valladolid, España; Instituto Endocrinología y Nutrición Valladolid, Valladolid, España.

High weight is a protective factor against osteoporosis and risk of fracture. In obesity, however, where overweight is associated to excess fat, this relationship does not appear to be so clear, excess weight has sometimes been associated to decreased bone mass. Obesity interferes with bone metabolism through mechanical, hormonal, and inflammatory factors. Read More

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http://dx.doi.org/10.1016/j.endonu.2016.08.005DOI Listing
December 2016
7 Reads

Use of healthcare resources and costs associated to the start of treatment with injectable drugs in patients with type 2 diabetes mellitus.

Endocrinol Nutr 2016 Dec 13;63(10):527-535. Epub 2016 Oct 13.

Departamento de Evaluación de Medicamentos, GlaxoSmithKline, Madrid, España.

Objectives: The main objective was to assess resource use and costs of starting treatment with insulin or injectable GLP-1 receptor analogues (GLP-1 RAs) in a Spanish population of patients with type 2 diabetes mellitus. Treatment adherence and persistence were also determined for both treatment groups.

Patients And Methods: A retrospective, non-interventional, observational study was conducted. Read More

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http://dx.doi.org/10.1016/j.endonu.2016.07.001DOI Listing
December 2016
15 Reads

Autosomal dominant hypocalcaemia: A novel mutation.

Endocrinol Nutr 2016 Nov 20;63(9):505-506. Epub 2016 Sep 20.

Secciòn de endocrinologia, Hospital Marqués de Valdecilla, Santander, España.

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http://dx.doi.org/10.1016/j.endonu.2016.08.001DOI Listing
November 2016
5 Reads

Severe systemic type 1 pseudohypoaldosteronism: 5 years of evolution.

Endocrinol Nutr 2016 Nov 18;63(9):502-505. Epub 2016 Sep 18.

Department of Pediatrics, Hospital de Braga, Sete Fontes, São Victor, 4710-243 Braga, Portugal.

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http://dx.doi.org/10.1016/j.endonu.2016.08.002DOI Listing
November 2016
10 Reads

Pituitary adenoma associated with pheochromocytoma/paraganglioma: A new form of multiple endocrine neoplasia.

Endocrinol Nutr 2016 Nov 14;63(9):506-508. Epub 2016 Sep 14.

Servicio de Endocrinología y Nutrición, Hospital Universitario de Bellvitge, Hospitalet de Llobregat, Barcelona, España.

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https://linkinghub.elsevier.com/retrieve/pii/S15750922163011
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http://dx.doi.org/10.1016/j.endonu.2016.07.007DOI Listing
November 2016
13 Reads

Associations of adiponectin and leptin levels with protein-energy wasting, in end stage renal disease patients.

Endocrinol Nutr 2016 Nov;63(9):449-457

Department of Nephrology, University Hospital of Heraklion, Heraklion, Crete, Greece.

Objective: The aim of the study was to examine the prevalence of protein-energy wasting (PEW) in hemodialysis (HD) and peritoneal dialysis (PD) patients in our center and determine whether adiponectin and leptin are involved in the development of PEW.

Design: Prospective (18 months).

Setting: University Hospital of Heraklion, Crete, Greece. Read More

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http://dx.doi.org/10.1016/j.endonu.2016.07.003DOI Listing
November 2016
8 Reads

Gut microbiota and type 2 diabetes mellitus.

Endocrinol Nutr 2016 Dec 12;63(10):560-568. Epub 2016 Sep 12.

Endocrinología y Nutrición, Hospital Clínico Universitario Virgen de la Victoria, Málaga, España. Electronic address:

In recent years, many studies have related gut microbiome to development of highly prevalent diseases such as type 2 diabetes and obesity. Obesity itself is associated to changes in the composition of gut microbiome, with a trend to an overgrowth of microorganisms more efficiently obtaining energy from diet. There are several mechanisms that relate microbiota to the onset of insulin resistance and diabetes, including changes in bowel permeability, endotoxemia, interaction with bile acids, changes in the proportion of brown adipose tissue, and effects associated to use of drugs like metformin. Read More

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http://dx.doi.org/10.1016/j.endonu.2016.07.008DOI Listing
December 2016
7 Reads

An update on probiotics, prebiotics and symbiotics in clinical nutrition.

Endocrinol Nutr 2016 Nov 12;63(9):482-494. Epub 2016 Sep 12.

UGC Endocrinología y Nutrición, Instituto de Investigación Biomédica de Málaga, Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, España; CIBERDEM, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CB07/08/0019), Instituto de Salud Carlos III, Madrid, España.

The concept of prebiotics, probiotics, and symbiotics and their use in different situations of daily clinical practice related to clinical nutrition is reviewed, as well as their role in the treatment/prevention of diarrhea (acute, induced by antibiotics, secondary to radiotherapy), inflammatory bowel disease (ulcerative colitis and pouchitis), in colonic health (constipation, irritable bowel), in liver disease (steatosis and minimum encephalopathy), and in intensive care, surgical, and liver transplantation. While their effectiveness for preventing antibiotic-induced diarrhea and pouchitis in ulcerative colitis appears to be shown, additional studies are needed to establish recommendations in most clinical settings. The risk of infection associated to use of probiotics is relatively low; however, there are selected groups of patients in whom they should be used with caution (as jejunum infusion). Read More

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http://dx.doi.org/10.1016/j.endonu.2016.07.006DOI Listing
November 2016
5 Reads

Is diabetes mellitus correctly registered and classified in primary care? A population-based study in Catalonia, Spain.

Endocrinol Nutr 2016 Nov 6;63(9):440-448. Epub 2016 Sep 6.

DAP-Cat group, Unitat de Suport a la Recerca Barcelona Ciutat, Institut Universitari d'Investigació en Atenció Primària Jordi Gol (IDIAP Jordi Gol), Barcelona, Spain; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Spain; Primary Health Care Center Raval Sud, Gerència d'Àmbit d'Atenció Primària Barcelona Ciutat, Institut Català de la Salut, Barcelona, Spain. Electronic address:

Objective: To assess the prevalence of miscoding, misclassification, misdiagnosis and under-registration of diabetes mellitus (DM) in primary health care in Catalonia (Spain), and to explore use of automated algorithms to identify them.

Methods: In this cross-sectional, retrospective study using an anonymized electronic general practice database, data were collected from patients or users with a diabetes-related code or from patients with no DM or prediabetes code but treated with antidiabetic drugs (unregistered DM). Decision algorithms were designed to classify the true diagnosis of type 1 DM (T1DM), type 2 DM (T2DM), and undetermined DM (UDM), and to classify unregistered DM patients treated with antidiabetic drugs. Read More

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http://dx.doi.org/10.1016/j.endonu.2016.07.004DOI Listing
November 2016
10 Reads

Clinical and economic benefits of integrated pump/CGM technology therapy in patients with type 1 diabetes in Colombia.

Endocrinol Nutr 2016 Nov 30;63(9):466-474. Epub 2016 Aug 30.

Medtronic Latinamerica Inc., Miami, FL, EE. UU.

Objective: To assess the long-term clinical and economic impact of integrated pump/CGM technology therapy as compared to multiple daily injections (MDI), for the treatment of type 1 diabetes (T1D) in Colombia.

Methods: The CORE Diabetes Model was used to simulate a hypothetical cohort of patients with T1D. Mean baseline characteristics were taken from a clinical study conducted in Colombia and a healthcare payer perspective was adopted, with a 5% annual discount rate applied to both costs and outcomes. Read More

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http://dx.doi.org/10.1016/j.endonu.2016.05.011DOI Listing
November 2016
32 Reads

Efficacy and safety of empagliflozin in combination with other oral hypoglycemic agents in patients with type 2 diabetes mellitus.

Endocrinol Nutr 2016 Dec 28;63(10):519-526. Epub 2016 Aug 28.

Eli Lilly and Company, UK, Basingstoke, Reino Unido; Faculty of Science, Liverpool Hope University, Liverpool, Reino Unido.

Introduction: To analyze the efficacy and safety of empagliflozin combined with other oral hypoglycemic agents in patients with type 2 diabetes mellitus.

Methods: Pooled analysis of three phase III trials in patients with type 2 diabetes mellitus (n=1,801) who received placebo or empagliflozin 10 or 25mg once daily for 24 weeks, in combination with metformin, metformin+sulphonylurea or pioglitazone ± metformin.

Results: Empagliflozin significantly decreased HbA1c (adjusted mean reduction vs placebo with empagliflozin 10mg: -0. Read More

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http://dx.doi.org/10.1016/j.endonu.2016.06.003DOI Listing
December 2016
18 Reads

Vitamin D status in Egyptian euthyroid multinodular non-toxic goiter patients and its correlation with TSH levels.

Endocrinol Nutr 2016 Oct 21;63(8):380-6. Epub 2016 Aug 21.

Clinical Pathology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

Background And Aim: Although the prevalence of MNG is widespread throughout the world, its pathogenesis is poorly understood, and the complex interactions of both genetic predisposition and the individuals' environment are likely. However, to the best of our knowledge, it remains unknown whether there is a relationship between vitamin D status and prevalence or pathogenesis of euthyroid MNG. Therefore, the goal of the present study was determination of vitamin D status in euthyroid MNG as well as exploration of the correlation between vitamin D status & TSH levels. Read More

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http://dx.doi.org/10.1016/j.endonu.2016.06.005DOI Listing
October 2016
16 Reads

Bone mineral density in anorexia nervosa: Only weight and menses recovery?

Endocrinol Nutr 2016 Nov 6;63(9):458-465. Epub 2016 Aug 6.

Centro Ecotest, Seville, Spain; Universidad de Sevilla, Seville, Spain.

Introduction: The study objectives were to analyze the presence of reduced bone mass in a sample of patients with anorexia nervosa (AN) and amenorrhea, to assess Bone Mineral Density (BMD) recovery after having a normal weight is reached and regular menses are resumed, and to predict BMD after a treatment period considering different variables (baseline BMD, baseline and final body mass index (BMI), treatment duration).

Material & Methods: 35 patients with AN (mean age 20.57±5. Read More

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http://dx.doi.org/10.1016/j.endonu.2016.06.006DOI Listing
November 2016
4 Reads

The diabetic paradox: Bone mineral density and fracture in type 2 diabetes.

Endocrinol Nutr 2016 Nov;63(9):495-501

Departamento de Endocrinología y Nutrición, Clínica Universidad de Navarra, Pamplona, España.

Type 2 diabetes mellitus prevalence and morbidity are increasing. Osteoporotic fractures are among the 'non-classical' complications of diabetes and been overlooked for a long time, maybe because of their complex diagnostic and therapeutic approach. The usual tools for preventing fragility fractures (such as the fracture risk assessment tool and bone densitometry) underestimate risk of fractures in type2 diabetic patients. Read More

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http://dx.doi.org/10.1016/j.endonu.2016.06.004DOI Listing
November 2016
7 Reads

Detection of people at risk of diabetes in community pharmacies of Pontevedra (Spain) (DEDIPO).

Endocrinol Nutr 2016 Oct;63(8):387-96

Centro de Información del Medicamento, Colegio Oficial de Farmacéuticos, Pontevedra, España.

Objective: The aim of this study was to detect people at risk of suffering diabetes or changes in carbohydrate metabolism and to refer them for possible diagnosis to health care centres. The number of diagnoses and costs for the pharmacy were recorded.

Methods: A cross-sectional, observational study was conducted in community pharmacies in Pontevedra in September-October of 2014. Read More

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http://dx.doi.org/10.1016/j.endonu.2016.06.002DOI Listing
October 2016
7 Reads

Use of lanreotide in combination with cabergoline or pegvisomant in patients with acromegaly in the clinical practice: The ACROCOMB study.

Endocrinol Nutr 2016 Oct 20;63(8):397-408. Epub 2016 Jul 20.

Endocrinología, Hospital Sant Pau, Pare Claret, 167, Barcelona, Spain.

Purpose: To describe real-world use of lanreotide combination therapy for acromegaly.

Patients And Methods: ACROCOMB is a retrospective observational Spanish study of patients with active acromegaly treated with lanreotide combination therapy between 2006 and 2011. 108 patients treated at 44 Spanish Endocrinology Departments were analyzed separately: 61 patients received lanreotide/cabergoline (cabergoline cohort) and 47 lanreotide/pegvisomant (pegvisomant cohort). Read More

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http://dx.doi.org/10.1016/j.endonu.2016.05.010DOI Listing
October 2016
25 Reads

Incidental versus non-incidental thyroid carcinoma: Clinical presentation, surgical management and prognosis.

Endocrinol Nutr 2016 Nov 11;63(9):475-481. Epub 2016 Jul 11.

Servicio de Cirugía General, Hospital General Universitario J.M. Morales Meseguer, Universidad de Murcia, Murcia, España.

Background And Objective: Thyroid cancer may be clinically evident as a tumor mass in the neck or as a histopathological incidental finding after thyroid surgery for an apparent benign condition. Our objective was to assess the differences in clinical signs, surgical management, and course between incidental and clinically diagnosed thyroid tumors.

Methods: A retrospective study was conducted on patients operated on for benign or malignant thyroid disease from January 2000 to March 2014. Read More

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http://dx.doi.org/10.1016/j.endonu.2016.05.009DOI Listing
November 2016
15 Reads

Nonalcoholic steatohepatitis and diabetes.

Endocrinol Nutr 2016 Oct 15;63(8):377-9. Epub 2016 Jul 15.

Unitat de Suport a la Recerca (USR) Metropolitana Nord, Institut d'Investigació en Atenció Primaria (IDIAP) Jordi Gol, Centro de Investigación en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Barcelona, España.

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http://dx.doi.org/10.1016/j.endonu.2016.06.001DOI Listing
October 2016
6 Reads

Pituitary apoplexy as presentation of atypical teratoid/rhabdoid tumor in an adult.

Endocrinol Nutr 2016 Aug-Sep;63(7):364-5. Epub 2016 Jun 24.

Departamento de Endocrinología y Nutrición, Hospital Universitario Puerta del Mar, Cádiz, España.

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http://dx.doi.org/10.1016/j.endonu.2016.05.004DOI Listing
November 2017
6 Reads

Comments on «Hipercarotinemia after bariatric surgery».

Endocrinol Nutr 2016 Aug-Sep;63(7):375. Epub 2016 Jun 24.

Endocrinología y Nutrición, Hospital Rey Juan Carlos, Móstoles, Madrid, España.

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http://dx.doi.org/10.1016/j.endonu.2016.05.006DOI Listing
June 2016
13 Reads

Comments on «Hipercarotinemia after bariatric surgery».

Endocrinol Nutr 2016 Aug-Sep;63(7):374-5. Epub 2016 Jun 23.

Servicio de Bioquímica Clínica, Hospital Universitario Puerta de Hierro-Majadahonda, Majadahonda, Madrid, España.

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http://dx.doi.org/10.1016/j.endonu.2016.05.007DOI Listing
June 2016
13 Reads

Comments on «Impaired awareness of hypoglycaemia in subjects with type 1 diabetes».

Endocrinol Nutr 2016 Oct 23;63(8):435. Epub 2016 Jun 23.

Endocrinología y Nutrición, Hospital Universitario Puerto Real, Cádiz, España.

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http://dx.doi.org/10.1016/j.endonu.2016.05.005DOI Listing
October 2016
4 Reads

Canagliflozin induced diabetic ketoacidosis.

Endocrinol Nutr 2016 Oct 23;63(8):430-1. Epub 2016 Jun 23.

Sección de Endocrinología y Nutrición, Hospital de Cabueñes, Gijón, Asturias, España.

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http://dx.doi.org/10.1016/j.endonu.2016.05.008DOI Listing
October 2016
11 Reads

The specific immunotherapy of autoimmune diseases through the nanomedicine.

Authors:
Joan Verdaguer

Endocrinol Nutr 2016 Nov 22;63(9):437-439. Epub 2016 Jun 22.

Unitat d'Immunologia, Departament de Medicina Experimental, Facultat de Medicina, Universitat de Lleida, Lleida, España; Institut de Recerca Biomèdica de Lleida (IRBLleida), Lleida, España; CIBER de Diabetes y Enfermedades Metabólicas (CIBERDEM), España. Electronic address:

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http://dx.doi.org/10.1016/j.endonu.2016.05.003DOI Listing
November 2016
7 Reads

Results from Cardiovascular Outcome Trials in Diabetes.

Endocrinol Nutr 2016 Aug-Sep;63(7):317-9. Epub 2016 Jun 17.

UGC Endocrinología y Nutrición, Hospital Universitario Virgen de la Victoria, Málaga, España.

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http://dx.doi.org/10.1016/j.endonu.2016.04.001DOI Listing
November 2017
11 Reads

Sincronous malignant struma ovarii and papillary thyroid carcinoma.

Endocrinol Nutr 2016 Aug-Sep;63(7):366-7. Epub 2016 Jun 11.

Servicio de Endocrinología, Complejo Hospitalario Universitario de Pontevedra, Pontevedra, España.

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http://dx.doi.org/10.1016/j.endonu.2016.05.002DOI Listing
November 2017
7 Reads

Perinatal outcome of macrosomic infants born to diabetic versus non-diabetic mothers.

Endocrinol Nutr 2016 Oct 4;63(8):409-13. Epub 2016 Jun 4.

Unidad de Neonatología y Unidad de Cuidados Intensivos Neonatales, Hospital Universitario Santa Lucía, Complejo Hospitalario Universitario de Cartagena, Cartagena, Murcia, España.

Objective: To assess the incidence and perinatal complications of macrosomic infants born to diabetic and non-diabetic mothers.

Patients And Methods: A six-year retrospective study of newborns at our hospital. A total of 996 macrosomic newborns were found. Read More

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http://dx.doi.org/10.1016/j.endonu.2016.04.010DOI Listing
October 2016
11 Reads

Thyroid dysfunction in the era of precision medicine.

Endocrinol Nutr 2016 Aug-Sep;63(7):354-63. Epub 2016 Jun 3.

Division of Endocrinology, Diabetes, and Metabolism, The John Hopkins University School of Medicine, Baltimore, MD, USA.

The launching of the Precision Medicine Initiative by the President of the United States in January 2015 was an invitation for all healthcare professionals to review their practice. This call should stimulate thyroidologists working in different areas (from basic research or epidemiology to the frontline of the clinical arena or to those designing public health programs) to be aware of this new outlook. The aim of the initiative is to eradicate imprecision in estimating the probability of a correct diagnosis, to be as sure as possible of the most effective treatment, and to maximize the chances of a successful outcome. Read More

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http://dx.doi.org/10.1016/j.endonu.2016.04.009DOI Listing
November 2017
58 Reads

Diabetes knowledge among Greek Type 2 Diabetes Mellitus patients.

Endocrinol Nutr 2016 Aug-Sep;63(7):320-6. Epub 2016 Jun 3.

Postgraduate Program in Diabetes Care, Department of Nursing, Alexander Technological Educational Institute, Sindos GR 57400, Thessaloniki, Greece.

Background & Objective: Diabetes knowledge has been shown to improve glycemic control and associate with several demographic parameters. In Greece, a country with high obesity rates, disease knowledge has never been evaluated in diabetic patients. This cross sectional study aimed to assess diabetes knowledge and its associations between social and demographic parameters, among Greek type 2 diabetes mellitus (T2DM) patients. Read More

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http://dx.doi.org/10.1016/j.endonu.2016.04.008DOI Listing
November 2017
21 Reads

D-lactic acidosis: A rare cause of metabolic acidosis.

Endocrinol Nutr 2016 Oct 3;63(8):433-4. Epub 2016 Jun 3.

Servicio de Endocrinología y Nutrición, Hospital Universitario de Bellvitge, L'Hospitalet de Llobregat, Barcelona, España.

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http://dx.doi.org/10.1016/j.endonu.2016.04.007DOI Listing
October 2016
11 Reads

False overt hyperthyroidism by interference in immunoassay.

Endocrinol Nutr 2016 Oct 31;63(8):431-2. Epub 2016 May 31.

Unidad de Diabetes, Endocrinología y Nutrición, Hospital General de Granollers, Granollers, Barcelona, España.

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http://dx.doi.org/10.1016/j.endonu.2016.05.001DOI Listing
October 2016
4 Reads

Medullary thyroid carcinoma as manifestation of the loss of heterozygosity in a patient with MEN1.

Endocrinol Nutr 2016 Aug-Sep;63(7):371-3. Epub 2016 May 27.

Department of Endocrinology and Nutrition, Hospital Clinic, Barcelona, Spain; Laboratory of Endocrine Disorders, IDIBAPS, Barcelona, Spain; Faculty of Medicine, University of Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.endonu.2016.03.005DOI Listing
November 2017
7 Reads

Study of the pathogenesis and treatment of diabetes mellitus through animal models.

Endocrinol Nutr 2016 Aug-Sep;63(7):345-53. Epub 2016 May 28.

Sección de Endocrinología y Nutrición, Complejo Hospitalario Universitario Insular Materno Infantil de Gran Canaria, Las Palmas de Gran Canaria, Canary Islands, Spain; Instituto Universitario de Investigaciones Biomédicas y Sanitarias de la Universidad de Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Canary Islands, Spain. Electronic address:

Most research in diabetes mellitus (DM) has been conducted in animals, and their replacement is currently a chimera. As compared to when they started to be used by modern science in the 17th century, a very high number of animal models of diabetes is now available, and they provide new insights into almost every aspect of diabetes. Approaches combining human, in vitro, and animal studies are probably the best strategy to improve our understanding of the underlying mechanisms of diabetes, and the choice of the best model to achieve such objective is crucial. Read More

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http://dx.doi.org/10.1016/j.endonu.2016.03.011DOI Listing
November 2017
7 Reads

Association between triglyceride/HDL cholesterol ratio and carotid atherosclerosis in postmenopausal middle-aged women.

Endocrinol Nutr 2016 Aug-Sep;63(7):327-32. Epub 2016 May 25.

Consejo de Epidemiología y Prevención Cardiovascular Dr. Mario Ciruzzi de la Sociedad Argentina de Cardiología, Buenos Aires, Argentina.

Background And Objective: The triglyceride/HDL cholesterol ratio, as a surrogate marker of insulin resistance, may be associated to presence of subclinical carotid atherosclerosis in postmenopausal women. The aim of this study was to explore this association.

Patients And Methods: Women (last menstrual period≥2 years) in primary prevention up to 65 years of age were recruited. Read More

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http://dx.doi.org/10.1016/j.endonu.2016.04.004DOI Listing
November 2017
5 Reads

Economic impact of and satisfaction with a high resolution thyroid nodule clinic at the endocrinology department.

Endocrinol Nutr 2016 Oct 25;63(8):414-20. Epub 2016 May 25.

Consulta Alta Resolución Patología Tiroidea, Servicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, IEN-Universidad de Valladolid, Valladolid, España.

Background And Objective: No conclusive data exist on the value of a high resolution thyroid nodule clinic for management of nodular thyroid disease. The aim of this study was to evaluate the economic impact of and user satisfaction with a high resolution thyroid nodule clinic (HRTNC) in coordination with primary care.

Patients And Method: A prospective, observational, descriptive study was conducted to analyze data from 3,726 patients (mean age 61±12 years; 85% women) evaluated at an HRTNC during 2014 and 2015. Read More

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http://dx.doi.org/10.1016/j.endonu.2016.04.005DOI Listing
October 2016
25 Reads

Pathogenesis of thyroid autoimmune disease: the role of cellular mechanisms.

Endocrinol Nutr 2016 Oct 24;63(8):421-9. Epub 2016 May 24.

Department of Endocrinology, Hospital Universitario de la Princesa, Instituto de Investigación Princesa, Universidad Autónoma de Madrid, C/ Diego de León 62, 28006 Madrid, Spain. Electronic address:

Hashimoto's thyroiditis (HT) and Graves' disease (GD) are two very common organ-specific autoimmune diseases which are characterized by circulating antibodies and lymphocyte infiltration. Although humoral and cellular mechanisms have been classically considered separately in the pathogenesis of autoimmune thyroid diseases (AITD), recent research suggests a close reciprocal relationship between these two immune pathways. Several B- and T-cell activation pathways through antigen-presenting cells (APCs) and cytokine production lead to specific differentiation of T helper (Th) and T regulatory (Treg) cells. Read More

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http://dx.doi.org/10.1016/j.endonu.2016.04.003DOI Listing
October 2016
16 Reads

Glucocorticoid resistance syndrome caused by two novel mutations in the NR3C1 gene.

Endocrinol Nutr 2016 Aug-Sep;63(7):369-71. Epub 2016 May 17.

Endocrinology and Diabetes Research Group, Hospital Universitario Cruces, BioCruces, CIBERER, CIBERDEM, UPV-EHU, Barakaldo, Basque Country, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.endonu.2016.03.010DOI Listing
November 2017
5 Reads

Reproductive options in osteogenesis imperfecta. A two cases report in the same family with a new mutation in COL1A1.

Endocrinol Nutr 2016 Aug-Sep;63(7):367-9. Epub 2016 May 10.

Servicio de Genética, Hospital Universitario de Getafe, Getafe, Madrid, España.

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http://dx.doi.org/10.1016/j.endonu.2016.04.002DOI Listing
November 2017
6 Reads

Metabolic syndrome and peripheral artery disease: Two related conditions.

Endocrinol Nutr 2016 Jun-Jul;63(6):258-64. Epub 2016 May 7.

Diplomada Universitaria en Enfermería, ABS Sant Andreu de la Barça, Barcelona, España.

Aims: To ascertain the prevalence of metabolic syndrome (MS) in patients with peripheral artery disease (PAD) at the Martorell primary care (PC) center. To analyze the differences in comorbidities and cardiovascular risk factors between patients with PAD with and without MS.

Methods: A cross-sectional, descriptive study on patients diagnosed with PAD according to computerized clinical records of the Martorell PC center. Read More

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http://dx.doi.org/10.1016/j.endonu.2016.03.007DOI Listing
November 2017
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Epidemiology of acromegaly in Ecuador.

Endocrinol Nutr 2016 Aug-Sep;63(7):333-8. Epub 2016 May 4.

Servicio de Gastroenterología, Hospital TMC, Guayaquil, Ecuador.

Objectives: To assess the epidemiology of acromegaly in the city of Guayaquil, Ecuador, and to compare our results to those reported in the literature.

Patients, Material And Methods: An analysis was made of retrospective and prospective data from all patients with acromegaly attending endocrinology clinics at the 4 main hospitals of the public health network of Guayaquil from January 2000 to December 2014. Age at diagnosis, estimated delay in diagnosis, imaging studies of pituitary gland, basal growth hormone (GH) level, GH after an oral glucose tolerance test (OGTT-GH), and serum levels of insulin-like growth factor 1 (IGF-1) were recorded. Read More

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http://dx.doi.org/10.1016/j.endonu.2016.03.009DOI Listing
November 2017
5 Reads

Clinical status of a cohort of patients with type 1 diabetes diagnosed more than 2 decades before. Results of a specific clinical follow-up program.

Endocrinol Nutr 2016 Aug-Sep;63(7):339-44. Epub 2016 May 4.

Unidad de Diabetes, Servicio de Endocrinología y Nutrición, ICMDiM (Institut de Malalties Digestives i Metabòliques), Hospital Clínic i Universitari de Barcelona. IDIBAPS (Institut d'Investigacions Biomèdiques August Pi i Sunyer), Barcelona, España. Electronic address:

Background And Objective: The clinical course of type 1 diabetes mellitus (T1DM) has changed in recent decades. The aim of our study was to assess the long-term (> 20 years) clinical status of a patient cohort with T1DM under a specific treatment and follow-up program.

Patients And Methods: A single center, observational, cross-sectional study was conducted of a patient cohort diagnosed with T1DM in the 1986-1994 period at our tertiary university hospital. Read More

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http://dx.doi.org/10.1016/j.endonu.2016.03.008DOI Listing
November 2017
16 Reads

Reply letter: Screening for thyroid disease in pregnancy.

Endocrinol Nutr 2016 Jun-Jul;63(6):312-3. Epub 2016 Apr 15.

Unidad de Endocrinología y Nutrición, Hospital Fundación Alcorcón, Alcorcón, Madrid, España. Electronic address:

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http://dx.doi.org/10.1016/j.endonu.2016.03.003DOI Listing
April 2016
8 Reads

Autoimmune limbic encephalopathy in a girl with type 1 diabetes. Clinical features and outcomes.

Endocrinol Nutr 2016 Jun-Jul;63(6):308-10. Epub 2016 Apr 19.

Servicio de Pediatría, Hospital Universitario del Sureste, Arganda del Rey, Madrid, España.

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http://dx.doi.org/10.1016/j.endonu.2016.03.004DOI Listing
November 2017
5 Reads