1,468 results match your criteria Endocrine Research [Journal]


Factors Influencing Serum Homocysteine Levels in Postmenopausal Osteoporotic Females - Comparison to Urinary Collagen Crosslinks.

Endocr Res 2019 Feb 14:1-9. Epub 2019 Feb 14.

d Department of Orthopedic Surgery , Hamamatsu University School of Medicine , Hamamatsu, Shizuoka , Japan.

Purpose: The correlation between serum levels of homocysteine and bone mineral density remains controversial. The aim of this study was to identify the potential factors associated with the levels of serum total homocysteine (S-Hcy) and urinary N-terminal telopeptide of type I collagen (U-NTX) in female osteoporotic patients.

Materials And Methods: This cross-sectional study included 163 female osteoporotic patients, aged between 48 and 91 years, who had never been treated with anti-osteoporosis therapy. Read More

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http://dx.doi.org/10.1080/07435800.2019.1577892DOI Listing
February 2019

TCF7L2 Expression Is Regulated by Cell Differentiation and Overfeeding in Human Adipose Tissue.

Endocr Res 2019 Feb 5:1-7. Epub 2019 Feb 5.

a Department of Endocrinology, Diabetes and Metabolism , Rigshospitalet , Copenhagen , Denmark.

Aim: The TCF7L2 gene variant rs7903146 has the largest effect on type 2 diabetes risk reported in genome-wide association studies, however its role in adipose tissue development and function is unknown. We investigate the association between gene variant rs7903146 and metabolic parameters and examine in vitro and ex vivo gene expression of TCF7L2 in human adipose tissue and progenitor cells from two independent populations of young healthy men with increased risk of type 2 diabetes due to low birth weight (LBW).

Design: Adipose tissue biopsies were excised from 40 healthy young men with low and normal birth weights (NBW) after a control and 5-day high-fat overfeeding diet. Read More

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http://dx.doi.org/10.1080/07435800.2019.1573827DOI Listing
February 2019
1 Read

The Non-Aromatic Δ5-Androstenediol Derivative of Dehydroepiandrosterone Acts as an Estrogen Agonist in Neonatal Rat Osteoblasts through an Estrogen Receptor α-related Mechanism.

Endocr Res 2018 Dec 24:1-16. Epub 2018 Dec 24.

c Departamento de Biología de la Reproducción Carlos Gual Castro , Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (INCMNSZ) , Mexico City , Mexico.

Purpose: It has been proposed that DHEA influences bone formation through, bioconversion to 17β-estradiol; however, DHEA is converted to Δ5-androstenediol (Δ5-Adiol), a metabolite with estrogenic potential involved in diverse biological process. To gain new insight into the role of Δ5-Adiol in bone cells, we examined DHEA and Δ5-Adiol effects in neonatal rat and human hFOB1.19 osteoblasts. Read More

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http://dx.doi.org/10.1080/07435800.2018.1559185DOI Listing
December 2018
2 Reads

Rates and Causes of Death among Adult Diabetes Patients in Romania.

Endocr Res 2018 Nov 13:1-6. Epub 2018 Nov 13.

a Endocrinology and diabetes , "Carol Davila" University of Medicine and Pharmacy , Bucharest , Romania.

Aims: To study the age and sex-dependent mortality rates and causes of death in a large Romanian diabetes cohort as compared with the general population.

Methods: All adult patients aged 20-64 years, receiving a free diabetes prescription in a major urban area during 2001-2008 were included and followed-up for death until December 31, 2011. Crude mortality rates and standardized mortality rate ratios (SMR) against general population (data from the National Institute of Statistics) were calculated. Read More

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https://www.tandfonline.com/doi/full/10.1080/07435800.2018.1
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http://dx.doi.org/10.1080/07435800.2018.1546734DOI Listing
November 2018
10 Reads

Relationship between metabolic syndrome and metabolic syndrome score with β-cell function by gender in non-diabetic Korean populations.

Endocr Res 2018 Oct 19:1-10. Epub 2018 Oct 19.

d Department of Preventive Medicine , Chosun University Medical School , Gwangju , South Korea.

Aims: The present study was conducted to assess the association of metabolic syndrome (MetS) and the MetS score (MSS) with β-cell function by gender in Korean non-diabetic populations.

Methods: This study used the data from the 2015 Korean National Health and Nutrition Examination Survey including 4380 adults, aged 20 or older.

Results: After adjusting for related variables (with exception of body mass index [BMI]), MetS (p < 0. Read More

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http://dx.doi.org/10.1080/07435800.2018.1524476DOI Listing
October 2018
2 Reads

Effect of insulin on thyroid cell proliferation, tumor cell migration, and potentially related mechanisms.

Endocr Res 2018 Sep 27:1-16. Epub 2018 Sep 27.

e Department of Endocrinology , The First Affiliated Hospital of Zhejiang Chinese Medical University , Hangzhou , Zhejiang , China.

Background: Diabetes has recently been identified as a risk factor for a variety of cancers, possibly due to hyperinsulinemia or exogenous insulin use. Thyroid cancer is the most common endocrine malignancy, and its incidence has been exponentially increasing worldwide at an alarming rate. The aim of this study was to establish whether insulin use affects thyroid cancer development and progression, specifically cell proliferation and migration in vitro. Read More

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http://dx.doi.org/10.1080/07435800.2018.1522641DOI Listing
September 2018
5 Reads

Endocrine complications of celiac disease: a case report and review of the literature.

Endocr Res 2018 Sep 10:1-19. Epub 2018 Sep 10.

c Department of Medicine , University of Texas Health Science Center at San Antonio , San Antonio , TX , USA.

Purpose: The purpose of this article is to review recent literature regarding endocrine disorders related to celiac disease (CD).

Methods: We describe a case report and review existing literature on the endocrine manifestations of CD.

Results: CD is an autoimmune disorder characterized by intestinal inflammation in response to gluten. Read More

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http://dx.doi.org/10.1080/07435800.2018.1509868DOI Listing
September 2018
7 Reads

A subset of patients with acquired partial lipodystrophy developing severe metabolic abnormalities.

Endocr Res 2018 Sep 5:1-9. Epub 2018 Sep 5.

a Division of Endocrinology and Metabolism , Dokuz Eylul University, Izmir.

Purpose/Aim of the study: Acquired partial lipodystrophy (APL) is a rare disease characterized by selective loss of adipose tissue. In this study, we aimed to present a subset of patients with APL, who developed severe metabolic abnormalities, from our national lipodystrophy registry.

Materials And Methods: Severe metabolic abnormalities were defined as: poorly controlled diabetes (HbA1c above 7% despite treatment with insulin more than 1 unit/kg/day combined with oral antidiabetics), severe hypertriglyceridemia (triglycerides above 500 mg/dL despite treatment with lipid-lowering drugs), episodes of acute pancreatitis, or severe hepatic involvement (biopsy-proven non-alcoholic steatohepatitis (NASH)). Read More

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http://dx.doi.org/10.1080/07435800.2018.1513029DOI Listing
September 2018
5 Reads

Growth hormone therapy in children with idiopathic short stature - the effect on appetite and appetite-regulating hormones: a pilot study.

Endocr Res 2018 Jul 6:1-11. Epub 2018 Jul 6.

a The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes , National Center for Childhood Diabetes, Schneider Children's Medical Center of Israel , Petah Tikva , Israel.

Aim: To investigate the effect of growth hormone (GH) therapy on appetite-regulating hormones and to examine the association between these hormones and the response to GH, body composition, and resting energy expenditure (REE).

Methods: Nine pre-pubertal children with idiopathic short stature underwent a standard meal test before and 4 months following initiation of GH treatment. Ghrelin, GLP-1, leptin, and insulin levels were measured; area under the curve (AUC) was calculated. Read More

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http://dx.doi.org/10.1080/07435800.2018.1493598DOI Listing
July 2018
19 Reads

Osteoprotegerin increases parallel to insulin resistance in obese adolescents.

Endocr Res 2018 Jun 7:1-7. Epub 2018 Jun 7.

a 4th Department of Pediatrics, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki , Papageorgiou General Hospital , Thessaloniki , Greece.

Purpose/Aim of the Study: Osteoprotegerin (OPG) is an α tumor necrosis factor receptor superfamily glucoprotein that acts as a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL), exerting an antiresoptive bone effect. It was recently shown that OPG/RANKL axis is activated during vascular calcification, contributing to atherosclerotic lesions formation. Additionally, OPG levels are charachterized as an independent risk factor for overall vascular mortality in obese adults. Read More

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http://dx.doi.org/10.1080/07435800.2018.1480630DOI Listing
June 2018
5 Reads

Correlation between thyroidal and peripheral blood total T cells, CD8 T cells, and CD8 T- regulatory cells and T-cell reactivity to calsequestrin and collagen XIII in patients with Graves' ophthalmopathy.

Endocr Res 2018 Nov 22;43(4):264-274. Epub 2018 May 22.

a Department of Academic Medicine , Sydney Medical School, Nepean, The University of Sydney , Kingswood , Australia.

Purpose/aim of the study: Graves' ophthalmopathy (GO) is closely related to the thyroid autoimmune disorder Graves' disease. Previous studies have suggested roles for thyroidal CD8 T cells and autoimmunity against calsequestrin-1 (CASQ)-1 in the link between thyroidal and orbital autoimmune reactions in GO. A role for autoimmunity against CollXIII has also been suggested. Read More

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http://dx.doi.org/10.1080/07435800.2018.1470639DOI Listing
November 2018
3 Reads

Endurance training alters YKL40, PERM1, and HSP70 skeletal muscle protein contents in men with type 2 diabetes mellitus.

Endocr Res 2018 May 21:1-8. Epub 2018 May 21.

a Institute of Cardiovascular Research and Sport Medicine, Department of Molecular and Cellular Sport Medicine , German Sport University Cologne , Cologne , Germany.

Background: The fight against type 2 diabetes mellitus (T2DM) is tremendously challenging. This pilot study investigates whether endurance training (3 times per week for 3 months, moderate intensity) can change the skeletal muscle protein contents of chitinase-3-like protein-1 (YKL40), peroxisome proliferator-activated receptor y coactivator-1 and estrogen-related receptor-induced regulator in muscle-1 (PERM1) and heat-shock protein-70 (HSP70), which have been discussed as novel therapeutically relevant targets.

Methods: Muscle biopsies were obtained from overweight/obese men with T2DM (n = 7, years = 63 ± 9) at T1 (6 weeks pre-training), T2 (1 week pre-training) and T3 (3 to 4 days post-training). Read More

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http://dx.doi.org/10.1080/07435800.2018.1474920DOI Listing
May 2018
7 Reads

Fibroblast growth factor 21, adiposity, and macronutrient balance in a healthy, pregnant population with overweight and obesity.

Endocr Res 2018 Nov 16;43(4):275-283. Epub 2018 May 16.

a Reproductive Endocrinology and Women's Health Laboratory , Pennington Biomedical Research Center-Louisiana State University , Baton Rouge , LA , USA.

Aim Of The Study: The regulation and actions of fibroblast growth factor 21 (FGF21) are responsive to energy status and macronutrient balance, and investigations of FGF21 in normal pregnancy, which could be informative for FGF21 biology, are seldom. The goal of our study was to examine FGF21 levels in a contemporary healthy, pregnant population.

Methods: We phenotyped 43 women with overweight and obesity during pregnancy for weight, body composition, and fasting blood. Read More

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http://dx.doi.org/10.1080/07435800.2018.1473421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215499PMC
November 2018
5 Reads

A new type of familial partial lipodystrophy: distinctive fat distribution and proteinuria.

Endocr Res 2018 Nov 7;43(4):258-263. Epub 2018 May 7.

f Division of Endocrinology , Dokuz Eylul University , Izmir , Turkey.

Purpose: To describe an interesting subtype of familial partial lipodystrophy (FPLD).

Methods: The phenotype of this distinctive FPLD subtype was studied in three Turkish female siblings.

Results: Mutation testing was negative for the genes associated with lipodystrophy syndromes. Read More

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http://dx.doi.org/10.1080/07435800.2018.1470188DOI Listing
November 2018
11 Reads
1.410 Impact Factor

Age-associated increase of thyroid hormone receptor β gene promoter methylation coexists with decreased gene expression.

Endocr Res 2018 Nov 7;43(4):246-257. Epub 2018 May 7.

a Department of Human Epigenetics , Mossakowski Medical Research Centre, PAS , Warsaw , Poland.

Purpose: It is not established if healthy aging of the thyroid axis is associated with alterations other than changes in hormone secretion.

Methods: The expression of thyroid hormone receptor β gene (THRB) was analyzed in peripheral blood mononuclear cells (PBMC) obtained from young, elderly, and long-lived individuals. The interaction between the 3'UTR of TRβ1 mRNA and selected miRNAs was measured using pmirGLO reporter vector. Read More

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http://dx.doi.org/10.1080/07435800.2018.1469648DOI Listing
November 2018
2 Reads

Skeletal response to treatment with teriparatide (TPD) after bisphosphonate in post-menopausal women with osteoporosis and a high prevalence of secondary risk factors in real-life setting of a metabolic bone clinic; effect of age and vitamin D status.

Endocr Res 2018 Aug 13;43(3):195-202. Epub 2018 Apr 13.

a Department of Chemical Pathology and Metabolic Medicine , St Thomas' Hospital , London , UK.

Purpose: Teriparatide (TPD) is a skeletal anabolic agent used in patients with severe post-menopausal osteoporosis (PMO) and steroid-induced osteoporosis who are at hish risk of fracture. Predictors of therapeutic response to teriparatide in real-life setting are not well characterised. We investigated potential factors associated with teriparatide response in post-menopausal women with established osteoporosis. Read More

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http://dx.doi.org/10.1080/07435800.2018.1454461DOI Listing
August 2018
3 Reads

Diagnostic evaluation in steroid-induced myopathy: case report suggesting clinical utility of quantitative muscle ultrasonography.

Endocr Res 2018 Nov 12;43(4):235-245. Epub 2018 Apr 12.

f Department of Translational Neurosciences and Neurotherapeutics , John Wayne Cancer Institute and Pacific Neuroscience Institute , Santa Monica , CA , USA.

Purpose: We present a patient with adrenal Cushing's syndrome causing steroid myopathy. The purpose of the case report is to illustrate the clinical usefulness of quantitative muscle ultrasonography for the assessment of glucocorticoid-induced changes in muscle mass (MM) and structure.

Methods: Assessments of physical performance, muscle strength, MM (i. Read More

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http://dx.doi.org/10.1080/07435800.2018.1461904DOI Listing
November 2018
7 Reads

Suppressive effects of metformin on T-helper 1-related chemokines expression in the human monocytic leukemia cell line THP-1.

Endocr Res 2018 Nov 9;43(4):228-234. Epub 2018 Apr 9.

a Department of Pediatrics , Kaohsiung Municipal Hsiao-Kang Hospital , Kaohsiung , Taiwan.

Purpose Of The Study: Type 1 and type 2 diabetes mellitus (DM) are chronic T-cell-mediated inflammatory diseases. Metformin is a widely used drug for type 2 DM that reduces the need for insulin in type 1 DM. However, whether metformin has an anti-inflammatory effect for treating DM is unknown. Read More

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https://www.tandfonline.com/doi/full/10.1080/07435800.2018.1
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http://dx.doi.org/10.1080/07435800.2018.1460605DOI Listing
November 2018
16 Reads

Effects of intracerebroventricularly injected glucagon-like peptide-2 on ethanol-induced gastric mucosal damage in rats.

Endocr Res 2018 Nov 9;43(4):220-227. Epub 2018 Apr 9.

a Department of Physiology, School of Medicine , Uludağ University , Bursa , Turkey.

Purpose: The present study aims to investigate the effects of intracerebroventricularly (i.c.v. Read More

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http://dx.doi.org/10.1080/07435800.2018.1460604DOI Listing
November 2018
9 Reads

Excess visceral adiposity is associated with diabetic retinopathy in a multiethnic Asian cohort with longstanding type 2 diabetes.

Endocr Res 2018 Aug 6;43(3):186-194. Epub 2018 Apr 6.

a Clinical Research Unit , Khoo Teck Puat Hospital , Singapore.

Purpose/Aim: Diabetic retinopathy (DR) is the most common diabetic microvascular complication, and it typically develops after 10 years of diabetes diagnosis. The primary aim of this study was to evaluate the association between adiposity and DR susceptibility among individuals with longstanding type 2 diabetes mellitus (T2D).

Materials And Methods: In this cross-sectional study, DR was assessed by fundus photography in 953 T2D subjects. Read More

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https://www.tandfonline.com/doi/full/10.1080/07435800.2018.1
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http://dx.doi.org/10.1080/07435800.2018.1451541DOI Listing
August 2018
16 Reads

Activation of tumor cell integrin αvβ3 by radiation and reversal of activation by chemically modified tetraiodothyroacetic acid (tetrac).

Endocr Res 2018 Nov 3;43(4):215-219. Epub 2018 Apr 3.

c Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sciences , Rensselaer , NY , USA.

Purpose: Integrin αvβ3 is an important structural and signaling protein of the plasma membrane of cancer cells and dividing blood vessel cells. The plastic extracellular domain of the protein binds to extracellular matrix proteins and plasma membrane proteins, changing cell-cell interactions and generating intracellular signals that influence cell behavior. αvβ3 also contains a receptor for thyroid hormone and derivatives, including tetraiodothyroacetic acid (tetrac). Read More

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http://dx.doi.org/10.1080/07435800.2018.1456550DOI Listing
November 2018
10 Reads

The cellular and molecular effects of the androgen receptor agonist, Cl-4AS-1, on breast cancer cells.

Endocr Res 2018 Aug 26;43(3):203-214. Epub 2018 Mar 26.

b Department of Pharmacology, School of Medicine , The University of Jordan , Amman , Jordan.

Purpose: The androgen receptor (AR) has attracted attention in the treatment of breast cancer. Due to the undesirable side effects of AR agonists, attempts have been undertaken to develop selective AR modulators. One of these compounds is Cl-4AS-1. Read More

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http://dx.doi.org/10.1080/07435800.2018.1455105DOI Listing
August 2018
8 Reads

Modifications in the spectrum of bone mass predictive factors with menopausal status.

Endocr Res 2018 Aug 12;43(3):176-185. Epub 2018 Mar 12.

a Endocrinology Department, "St. Spiridon" Hospital , "Grigore T. Popa" University of Medicine and Pharmacy , Iasi , Romania.

Purpose: Fat mass (FM) is a source of adipocytokines, with both positive and negative bone consequences. We aimed to investigate the role of body composition and adipokines as predictive factors for bone mass in women.

Methodology: This cross-sectional study included 93 women (38 premenopausal and 55 postmenopausal). Read More

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https://www.tandfonline.com/doi/full/10.1080/07435800.2018.1
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http://dx.doi.org/10.1080/07435800.2018.1448991DOI Listing
August 2018
12 Reads

Vasoactive androgens: Vasorelaxing effects and their potential regulation of blood pressure.

Endocr Res 2018 Aug 12;43(3):166-175. Epub 2018 Mar 12.

b Instituto de Investigaciones Biomédicas, Departamento de Biología Celular y Fisiología , Universidad Nacional Autónoma de México , Mexico City , Mexico.

Background: Testosterone, 5α- and 5β-dihydrotestosterone (-DHT) induce an acute in vitro vasorelaxation and in vivo vasodepressor, hypotensive and antihypertensive responses. Our aim was to study whether androgen-induced blood pressure (BP) reduction is involved with a blockade of Ca influx through L-type voltage-operated calcium channels (L-VOCCs) and/or the signaling pathways of α-adrenoceptors to induce vasoconstriction, which are one of the major mechanisms of BP maintenance.

Materials And Methods: The relaxing potency and efficacy of each androgen in large conduit (thoracic aorta) and resistance (mesenteric) arteries from male hypertensive (SHR) and normotensive (WKY) rats were established. Read More

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http://dx.doi.org/10.1080/07435800.2018.1448868DOI Listing
August 2018
5 Reads

Diabetic serum from older women increases adipogenic differentiation in mesenchymal stem cells.

Endocr Res 2018 Aug 9;43(3):155-165. Epub 2018 Mar 9.

a Division of Endocrinology, Diabetes & Metabolism, Department of Medicine , Johns Hopkins University School of Medicine , Baltimore , Maryland.

Background: Paradoxically, elderly persons with type 2 diabetes mellitus (T2DM) fracture despite having higher bone density than nondiabetics. Systemic factors associated with aging and T2DM may have detrimental, local effects on the skeleton. One such factor could be by altering the microenvironment of the mesenchymal stem cells (MSCs), multipotent progenitors capable of differentiating into adipocytes or osteoblasts. Read More

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http://dx.doi.org/10.1080/07435800.2018.1441868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062440PMC
August 2018
6 Reads

MIBI scintigraphy of parathyroid adenomas: correlation with biochemical and histological markers.

Endocr Res 2018 Aug 20;43(3):141-148. Epub 2018 Feb 20.

e Nuklearmedizinische Klinik , Universitaetsklinikum Erlangen , Erlangen , Germany.

Purpose: In this study, we tested the hypothesis that MIBI-positive and MIBI-negative adenomas of parathyroid glands (APGs) have distinct biochemical and histological markers that could help differentiate MIBI-positive from MIBI-negative APGs.

Patients And Methods: 40 patients with 41 APGs were included in the study. Patients were enrolled in the study after MIBI scintigraphy examinations had been carried out. Read More

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http://dx.doi.org/10.1080/07435800.2018.1437747DOI Listing
August 2018
5 Reads

Association of adiponectin/leptin ratio with carbohydrate and lipid metabolism parameters in HIV-infected patients during antiretroviral therapy.

Endocr Res 2018 Aug 16;43(3):149-154. Epub 2018 Feb 16.

a Carol Davila University of Medicine and Pharmacy , Bucharest , Romania.

Background: Adiponectin and leptin are adipose tissue hormones that regulate important lipid and glucose metabolic pathways. Our objective was to evaluate the interplay of these hormones described by the adiponectin/leptin ratio (ALR) in correlation to lipid and carbohydrate metabolism parameters in nondiabetic HIV-infected patients during antiretroviral therapy (ART).

Materials And Methods: We enrolled consecutive nondiabetic patients with confirmed HIV infection, undergoing stable ART regimens for at least six months. Read More

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http://dx.doi.org/10.1080/07435800.2018.1439058DOI Listing
August 2018
19 Reads

Occult urolithiasis in asymptomatic primary hyperparathyroidism.

Endocr Res 2018 May 5;43(2):106-115. Epub 2018 Feb 5.

a Division of Endocrinology, Department of Medicine , Columbia University, College of Physicians and Surgeons , New York.

Objective: Recent international guidelines suggest renal imaging to detect occult urolithiasis in all patients with asymptomatic primary hyperparathyroidism (PHPT), but data regarding their prevalence and associated risk factors are limited. We evaluated the prevalence and risk factors for occult urolithiasis.

Methods: Cross-sectional analysis of 96 asymptomatic PHPT patients from a university hospital in the United States with and without occult nephrolithiasis. Read More

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http://dx.doi.org/10.1080/07435800.2018.1431275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042842PMC
May 2018
11 Reads

Impact of admission serum calcium levels on mortality in hospitalized patients.

Endocr Res 2018 May 30;43(2):116-123. Epub 2018 Jan 30.

d Division of Pulmonary and Critical Care Medicine, Department of Medicine , Mayo Clinic , Rochester , MN , USA.

Objectives: To assess the relationship between admission serum calcium levels and in-hospital mortality in all hospitalized patients.

Methods: All adult hospitalized patients who had admission serum calcium levels available between years 2009 and 2013 were enrolled. Admission serum calcium was categorized based on its distribution into six groups (<7. Read More

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https://www.tandfonline.com/doi/full/10.1080/07435800.2018.1
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http://dx.doi.org/10.1080/07435800.2018.1433200DOI Listing
May 2018
10 Reads

Secondary and tertiary preventions of thyroid disease.

Endocr Res 2018 May 10;43(2):124-140. Epub 2018 Jan 10.

a Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences , Tehran , Iran.

Introduction: Secondary and tertiary preventions are concerned with the recognition of the disease process in a very early stage and delay in progression to complete disease and minimization of complications and the impact of illness.

Methods: All articles related to secondary and tertiary prevention of thyroid diseases were reviewed. Using related key words, articles published between 2001 and 2015 were evaluated, categorized, and analyzed. Read More

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http://dx.doi.org/10.1080/07435800.2018.1424720DOI Listing
May 2018
11 Reads
1.410 Impact Factor

All-cause and cardiovascular mortality associated with sulphonylurea and metformin therapy in type 2 diabetes.

Endocr Res 2018 May 8;43(2):97-105. Epub 2018 Jan 8.

a Department of Endocrinology and diabetes , "Carol Davila" University of Medicine and Pharmacy , Bucharest , Romania.

Purpose: To test the hypothesis that cumulative exposure to sulphonylurea (SU) or metformin (MET) have different effects on mortality when taken as a replacement or add-on of one for the other.

Methods: All consecutive diabetes patients aged over 20 years were screened at their first diabetes outpatient visit between 2001 and 2008 (n = 79869). Only patients on MET (n = 11374) or SU (n = 18502) monotherapy were retained. Read More

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http://dx.doi.org/10.1080/07435800.2017.1422745DOI Listing
May 2018
11 Reads

Association between anemia at three different time points and new-onset diabetes after kidney transplantation--a retrospective cohort study.

Endocr Res 2018 May 4;43(2):90-96. Epub 2018 Jan 4.

a Sackler Faculty of Medicine , Tel Aviv University , Tel Aviv , Israel.

Purpose: Anemia has been reported to be associated with diabetes, but the association between new-onset diabetes after transplantation (NODAT) and anemia has not been reported.

Methods: Patients who underwent kidney transplantation and did not have diabetes prior to transplantation were included in this study. Hemoglobin levels and the prevalence of anemia (hemoglobin <12 g/dL in females and <13 g/dL in males) were evaluated at three time points (prior to transplantation, 6 months following transplantation or 1 month before the development of NODAT, 2 years following transplantation, or following the development of NODAT) and were compared between those who developed NODAT and those who did not. Read More

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http://dx.doi.org/10.1080/07435800.2017.1422516DOI Listing
May 2018
11 Reads

The effect of weight loss on body composition, serum bone markers, and adipokines in prepubertal obese children after 1-year intervention.

Endocr Res 2018 May 1;43(2):80-89. Epub 2017 Dec 1.

c Department of Epidemiology and Biostatistics , Institute of Mother and Child , Warsaw , Poland.

Purpose/Aim: The influence of weight loss on bone turnover and bone quality in childhood remains controversial, but it may implicate interactions between adiposity and bone metabolism. Therefore, we studied the relationships between bone markers and adipokines during weight loss in obese children.

Materials And Methods: We determined serum leptin, soluble leptin receptor, adiponectin, bone alkaline phosphatase (BALP), C-terminal telopeptide of type I collagen (CTX-I), osteocalcin (OC), carboxylated-OC (Gla-OC), undercarboxylated-OC (Glu-OC), sclerostin, body composition, and bone mineral density (BMD) in 40 obese prepubertal children before and after therapy. Read More

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http://dx.doi.org/10.1080/07435800.2017.1403444DOI Listing
May 2018
13 Reads

Reduced insulin sensitivity in differentiated thyroid cancer patients with suppressed TSH.

Endocr Res 2018 May 30;43(2):73-79. Epub 2017 Oct 30.

a Division of Endocrinology, Department of Internal Medicine , University of Campinas , Campinas , Brazil.

Objective: TSH-suppression is a therapy for thyroid cancer management, but it may lead to adverse effects, which should be balanced with its benefits. Previous studies evaluating the consequences of TSH suppression on insulin sensitivity have only been done with indirect techniques, and results were controversial. Therefore, we aimed to assess insulin sensitivity in patients with thyroid cancer and suppressed thyroid-stimulating hormone (TSH) with the most appropriate direct method (hyperinsulinemic-euglycemic clamp) in order to get a more conclusive response about the topic. Read More

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http://dx.doi.org/10.1080/07435800.2017.1390673DOI Listing
May 2018
5 Reads

Body weight predicts Nicotinamide N-Methyltransferase activity in mouse fat.

Endocr Res 2018 Feb 16;43(1):55-63. Epub 2017 Oct 16.

a Medizinische Klinik und Poliklinik I, Abteilung für Nephrologie, Universitätsklinikum Würzburg , Würzburg , Germany.

Aim: Nicotinamide N-methyltransferase (NNMT) is a novel regulator of energy homeostasis in adipose tissue. NNMT expression is higher in obese mice than in lean mice, and NNMT knockdown prevents diet-induced obesity. Little is known about the regulation of enzyme activity during the development of obesity. Read More

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http://dx.doi.org/10.1080/07435800.2017.1381972DOI Listing
February 2018
9 Reads

Factors influencing the outcome from ultrasonography-guided fine-needle aspiration of benign thyroid cysts and partially cystic thyroid nodules: A multicenter study.

Endocr Res 2018 May 16;43(2):65-72. Epub 2017 Oct 16.

g Department of Radiology , Chung-Ang University Hospital, Chung-Ang University College of Medicine , Seoul , South Korea.

Purpose: The effect of ultrasonography (US)-guided fine-needle aspiration (US-FNA) for the collapse of benign cystic thyroid nodules is still unclear. This study aimed to assess the positive response rate following US-FNA of the cystic component of thyroid cysts and of partially cystic thyroid nodules (PCTNs), and to evaluate the factors influencing the outcome.

Methods: From June to December 2013, seven radiologists at seven institutions prospectively performed US-FNA on 320 cystic thyroid nodules in 320 patients. Read More

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https://www.tandfonline.com/doi/full/10.1080/07435800.2017.1
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http://dx.doi.org/10.1080/07435800.2017.1381973DOI Listing
May 2018
15 Reads
1.410 Impact Factor

Postmeal increment in intact glucagon-like peptide 1 level, but not intact glucose-dependent insulinotropic polypeptide levels, is inversely associated with metabolic syndrome in patients with type 2 diabetes.

Endocr Res 2018 Feb 13;43(1):47-54. Epub 2017 Oct 13.

a Department of Internal Medicine , Jeju National University Hospital , Jeju-si , Republic of Korea.

Purpose: Metabolic syndrome increases the risk of cardiovascular disease. Recently glucagon-like peptide 1 (GLP-1) agonists proved to be effective in preventing cardiovascular disease (CVD) in patients with type 2 diabetes. We investigated the association of blood incretin levels with metabolic syndrome in patients with type 2 diabetes. Read More

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http://dx.doi.org/10.1080/07435800.2017.1379023DOI Listing
February 2018
17 Reads

Role of sclerostin and dkk1 in bone remodeling in type 2 diabetic patients.

Endocr Res 2018 Feb 3;43(1):29-38. Epub 2017 Oct 3.

a Department of Endocrinology , The Third Hospital of Hebei Medical University , Shijiazhuang , China.

Purpose: This study aimed to investigate the role of sclerostin and dkk1 in the bone metabolism of type 2 diabetic patients.

Methods: This cross-sectional study included 95 inpatients with type 2 diabetes mellitus. We divided the patients into three groups (i. Read More

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http://dx.doi.org/10.1080/07435800.2017.1373662DOI Listing
February 2018
29 Reads

The role of the ovarian cycle and the effects of mitogen-induced cytokines on human prolactin gene expression in peripheral blood mononuclear cells.

Endocr Res 2018 Feb 3;43(1):39-46. Epub 2017 Oct 3.

a Departamento de Biología de la Reproducción Dr. Carlos Gual Castro , Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán , Mexico City , Mexico.

Background: little is known on the influences of normal menstrual cycle on prolactin gene expression in immune cells.

Aim Of The Study: to determine the effects of the ovarian cycle on prolactin and its receptor expression.

Methods: peripheral blood mononuclear cells (PBMC) were obtained from twenty-six normal menstruating women at different intervals of their menstrual cycle. Read More

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http://dx.doi.org/10.1080/07435800.2017.1374967DOI Listing
February 2018
14 Reads

Effect of parathyroidectomy on osteopontin and undercarboxylated osteocalcin in patients with primary hyperparathyroidism.

Endocr Res 2018 Feb 22;43(1):21-28. Epub 2017 Sep 22.

f Department of Surgery , Christiana Care Health System , Newark , DE , USA.

Purpose: Surgical treatment for primary hyperparathyroidism (PHPT) improves bone metabolism. Osteocalcin (OC) and its undercarboxylated form (ucOC) are associated with bone and energy metabolism. Osteopontin (OPN), a multifunctional protein expressed in bone, is involved in resorption, along with β-carboxyl-terminal cross-linking telopeptide of type 1 collagen (β-CTX), and osteoprotegerin (OPG). Read More

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http://dx.doi.org/10.1080/07435800.2017.1369432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082020PMC
February 2018
18 Reads

Association of ADAMTS4 and ADAMTS9 levels with cardiovascular risk in patients with primary hyperparathyroidism.

Endocr Res 2018 Feb 22;43(1):15-20. Epub 2017 Sep 22.

a Department of Endocrinology and Metabolism , Diskapi Yildirim Beyazit Training and Research Hospital , Ankara , Turkey.

Purpose: Primary hyperparathyroidism (PHPT) has been associated with increased incidence of morbidity and mortality of the cardiovascular system. The pathogenetic mechanisms underlying this association are still not completely clear. A disintegrin and metalloproteinase with thrombospondin-like motifs (ADAMTS) play a critical role in atherosclerosis. Read More

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http://dx.doi.org/10.1080/07435800.2017.1368543DOI Listing
February 2018
10 Reads

Comparison of 30 mCi and 50 mCi I-131 doses for ablation of thyroid remnant in papillary thyroid cancer patients.

Endocr Res 2018 Feb 25;43(1):11-14. Epub 2017 Jul 25.

a Department of Medicine , University of Alberta , Edmonton , Alberta , Canada.

Purpose Of The Study: To compare efficacy of thyroid remnant ablation using 30 mCi or 50 mCi 131-I in papillary thyroid cancer patients.

Materials And Methods: Five hundred and fifteen consecutive patients with Tumor-Node-Metastasis (TNM) stages T1-T3 N1/N0/NX receiving either 30 mCi or 50 mCi I-131 were analyzed for the effectiveness of remnant ablation using rhTSH-stimulated serum thyroglobulin. One hundred and five consecutive patients receiving 100 mCi I-131 were analyzed for the incidence of radiation thyroiditis and sialadenitis. Read More

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http://dx.doi.org/10.1080/07435800.2017.1346662DOI Listing
February 2018
17 Reads

The effects of vitamin D and evening primrose oil co-supplementation on lipid profiles and biomarkers of oxidative stress in vitamin D-deficient women with polycystic ovary syndrome: A randomized, double-blind, placebo-controlled trial.

Endocr Res 2018 Feb 25;43(1):1-10. Epub 2017 Jul 25.

c Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences , Kashan , I.R . Iran.

Purpose Of The Study: There was inconsistent evidence about the benefit of vitamin D plus evening primrose oil (EPO) supplement intake on lipid profiles and reduced oxidative stress among women with polycystic ovary syndrome (PCOS). The current study was performed to evaluate the effects of vitamin D plus EPO supplementation on lipid profiles and biomarkers of oxidative stress in vitamin D-deficient women with PCOS.

Materials And Methods: This randomized, double-blind, placebo-controlled trial was performed among 60 vitamin D-deficient women with PCOS. Read More

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http://dx.doi.org/10.1080/07435800.2017.1346661DOI Listing
February 2018
28 Reads

Influence of endurance training on skeletal muscle mitophagy regulatory proteins in type 2 diabetic men.

Endocr Res 2017 Nov 24;42(4):325-330. Epub 2017 May 24.

a Department of Molecular and Cellular Sport Medicine, Institute of Cardiovascular Research and Sport Medicine , German Sport University Cologne , Germany.

Background: Mitophagy is a form of autophagy for the elimination of mitochondria. Mitochondrial content and function are reduced in the skeletal muscle of patients with type 2 diabetes mellitus (T2DM). Physical training has been shown to restore mitochondrial capacity in T2DM patients, but the role of mitophagy has not been examined in this context. Read More

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http://dx.doi.org/10.1080/07435800.2017.1323914DOI Listing
November 2017
13 Reads

Hypopituitarism after gamma knife radiosurgery for pituitary adenoma.

Endocr Res 2017 Nov 24;42(4):318-324. Epub 2017 May 24.

b Department of Endocrinology , University Hospital Centre Zagreb , Zagreb , Croatia.

Purpose: The aim of the study was to investigate the incidence of and risk factors for hypopituitarism after gamma knife radiosurgery (GKRS) for pituitary adenoma.

Materials And Methods: We conducted a retrospective analysis of the pituitary function of 90 patients who underwent GKRS for pituitary adenoma at the University Hospital Centre Zagreb between 2003 and 2014. Twenty seven of them met the inclusion criteria and the others were excluded from the study due to pituitary insufficiency which was present before GKRS. Read More

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http://dx.doi.org/10.1080/07435800.2017.1323913DOI Listing
November 2017
24 Reads

Follow-up of patients with thyroglobulin-antibodies: Rising Tg-Ab trend is a risk factor for recurrence of differentiated thyroid cancer.

Endocr Res 2017 Nov 16;42(4):302-310. Epub 2017 May 16.

a Department of Surgical Oncology and Endocrine Surgery , University Medical Center Utrecht , Utrecht , The Netherlands.

Purpose: Differentiated thyroid cancer is the most common endocrine malignancy. Recurrences (5-20%) are the main reason for follow-up. Thyroglobulin (Tg) has proven to be an excellent disease marker, but thyroglobulin-antibodies (Tg-Ab) may interfere with Tg measurement, leading to over or underestimation. Read More

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http://dx.doi.org/10.1080/07435800.2017.1319858DOI Listing
November 2017
50 Reads

Trends in white blood cell and platelet indices in a comparison of patients with papillary thyroid carcinoma and multinodular goiter do not permit differentiation between the conditions.

Endocr Res 2017 Nov 16;42(4):311-317. Epub 2017 May 16.

a Second Department of Propedeutic Surgery , " Laiko" General Hospital, National and Kapodistrian University of Athens, Medical School , Athens , Greece.

Aim: Carcinogenesis has been related to systematic inflammatory response. Our aim was to study white blood cell and platelet indices as markers of this inflammatory response in thyroid cancer and to associate them with various clinicopathological parameters.

Methods: We included 228 patients who underwent thyroidectomy within a period of 54 months, 89 with papillary thyroid carcinoma and 139 with multinodular hyperplasia. Read More

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http://dx.doi.org/10.1080/07435800.2017.1319859DOI Listing
November 2017
14 Reads

Increased kallistatin levels in patients with obesity and prediabetes compared to normal glucose tolerance.

Endocr Res 2017 May 16;42(2):163-168. Epub 2017 Feb 16.

a Clinic of Endocrinology, University Hospital "Alexandrovska" , Department of Internal Diseases, Medical University - Sofia , Sofia , Bulgaria.

Purpose: Kallistatin is a member of serine protease inhibitors (SERPIN) family, which has various functions such as regulation of cardiovascular function and blood vessels development. Its levels are elevated in patients with type 1 and type 2 diabetes with chronic diabetic complications. The aim of the present study was to compare serum kallistatin levels between obese subjects with prediabetes and with normal glucose tolerance. Read More

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http://dx.doi.org/10.1080/07435800.2017.1286671DOI Listing
May 2017
19 Reads
3 Citations
1.410 Impact Factor

The vitamin D receptor functional variant rs2228570 (C>T) does not associate with type 2 diabetes mellitus.

Endocr Res 2017 Nov 7;42(4):331-335. Epub 2017 Apr 7.

a Department of Experimental Medicine , Sapienza University of Rome , Rome , Italy.

Aim: Vitamin D acts through the binding to the vitamin D receptor (VDR). Several polymorphisms in VDR gene have been studied. Among these, the rs2228570 C>T (FokI) variant has been demonstrated to be functional, leading to a protein with a different size and activity. Read More

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http://dx.doi.org/10.1080/07435800.2017.1305965DOI Listing
November 2017
23 Reads

Association between serum gamma-glutamyl transferase and serum uric acid levels in Chinese females: A cross-sectional study.

Endocr Res 2017 Nov 23;42(4):296-301. Epub 2017 Mar 23.

a Department of Endocrinology , The Affiliated Hospital of Luzhou Medical College , Luzhou , China.

Objective: To investigate the association between serum gamma-glutamyl transferase (GGT) levels and serum uric acid levels in middle-aged and elderly Chinese females.

Methods: A cross-sectional population survey was performed in Luzhou, China (2014). Questionnaires, physical examinations and biochemical tests were conducted. Read More

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http://dx.doi.org/10.1080/07435800.2017.1300809DOI Listing
November 2017
18 Reads