37,692 results match your criteria Endocarditis


Hypertrophic obstructive cardiomyopathy and mitral regurgitation in Libman-Sacks endocarditis.

Gen Thorac Cardiovasc Surg 2018 Dec 5. Epub 2018 Dec 5.

Department of Cardiovascular Surgery, Mitsubishi Kyoto Hospital, 1 Goshomachi, Nishikyo-ku, Kyoto, 615-8087, Japan.

Hypertrophic obstructive cardiomyopathy in Libman-Sacks endocarditis is quite rare and the correct etiological relationship between them is unknown. Some changes may cause a secondary disorganization of the ordinary muscle structure, making a disarray pattern with irregular interwoven myocyte fibers. This case report describes one of the first cases of ventricular septal myectomy and mitral valve replacement for hypertrophic obstructive cardiomyopathy and mitral valve regurgitation associated with Libman-Sacks endocarditis. Read More

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December 2018

MRI Presentation of Infectious Intracranial Aneurysms in Infective Endocarditis.

Neurocrit Care 2018 Dec 5. Epub 2018 Dec 5.

Cerebrovascular Center, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA.

Background: The radiographic appearance of infectious intracranial aneurysms (IIAs) of infective endocarditis (IE) on magnetic resonance imaging (MRI) of brain is varied. We aimed to describe the IIA-specific MRI features in a series of patients with IIAs.

Methods: Records of patients with active IE who had digital subtraction angiography (DSA) at a tertiary medical center from January 2011 to December 2016 were reviewed. Read More

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December 2018
1 Read

Trends in Drug Use-Associated Infective Endocarditis and Heart Valve Surgery, 2007 to 2017: A Study of Statewide Discharge Data.

Ann Intern Med 2018 Dec 4. Epub 2018 Dec 4.

University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (A.J.S., D.L.R.).

Background: Drug use-associated infective endocarditis (DUA-IE) is increasing as a result of the opioid epidemic. Infective endocarditis may require valve surgery, but surgical treatment of DUA-IE has invoked controversy, and the extent of its use is unknown.

Objective: To examine hospitalization trends for DUA-IE, the proportion of hospitalizations with surgery, patient characteristics, length of stay, and charges. Read More

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December 2018

Drug-Associated Infective Endocarditis Trends: What's All the Buzz About?

Authors:
Alysse G Wurcel

Ann Intern Med 2018 Dec 4. Epub 2018 Dec 4.

Tufts Medical Center and Tufts University, Boston, Massachusetts (A.G.W.).

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December 2018

Oral antibiotics in infective endocarditis.

Authors:
David Isaacs

J Paediatr Child Health 2018 Dec;54(12):1401-1402

Children's Hospital at Westmead, Sydney.

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December 2018

Pulmonary Valve Prosthesis Endocarditis Caused By .

Thorac Cardiovasc Surg Rep 2018 Jan 29;7(1):e47-e49. Epub 2018 Nov 29.

Center of Infectious Diseases, Heidelberg University Hospital, Heidelberg, Germany.

  is a gram-negative bacterium assigned to the family of . Less than 1% of Q-fever infection leads to infective endocarditis (IE). Cases of reported pulmonary valve (PV) prosthesis endocarditis are scarce. Read More

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January 2018

Valve durability after transcatheter aortic valve implantation.

J Thorac Dis 2018 Nov;10(Suppl 30):S3629-S3636

Division of Cardiology, University of Washington, Seattle, WA, USA.

Transcatheter aortic valve implantation (TAVI) is a minimally invasive procedure to treat severe symptomatic aortic stenosis. While the TAVI procedure can be performed safely and provide excellent 5-year results, little is known about long-term durability. TAVI valves are composed of bioprosthetic leaflets are prone to deterioration, which are categorized as structural valve deterioration (SVD) and non-SVD. Read More

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November 2018

Surgical treatment of right-sided infective endocarditis.

J Thorac Cardiovasc Surg 2018 Sep 25. Epub 2018 Sep 25.

Heart and Vascular Institute, Department of Thoracic and Cardiovascular Surgery. Electronic address:

Objective: Right-sided infective endocarditis is increasing because of increasing prevalence of predisposing conditions, and the role and outcomes of surgery are unclear. We therefore investigated the surgical outcomes for right-sided infective endocarditis.

Methods: From January 2002 to January 2015, 134 adults underwent surgery for right-sided infective endocarditis. Read More

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September 2018

The toll of complicated endocarditis and septic sequela: Old wives' tales and dogma.

J Thorac Cardiovasc Surg 2018 Nov 3. Epub 2018 Nov 3.

Department of Surgery, University of Kentucky, Lexington, Ky. Electronic address:

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November 2018

MS2-Affinity Purification Coupled With RNA Sequencing Approach in the Human Pathogen Staphylococcus aureus.

Methods Enzymol 2018 25;612:393-411. Epub 2018 Sep 25.

Architecture et Réactivité de l'ARN, Université de Strasbourg, IBMC-CNRS, Strasbourg, France. Electronic address:

Staphylococcus aureus is a Gram-positive major human pathogen involved in a wide range of human infectious diseases (from minor skin infections to septicemia, endocarditis or toxic shock syndrome). The treatment of S. aureus infections is very challenging due to the emergence of multiple antibiotic-resistant isolates. Read More

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September 2018

[Antibiotic prophylaxis in urodynamics: Clinical practice guidelines using a formal consensus method].

Prog Urol 2018 Nov 27. Epub 2018 Nov 27.

Service d'urologie, université Paris-7, hôpital Bichat Claude-Bernard, AP-HP, 46, rue Henri-Huchard, 75018 Paris, France.

Objective: The aim of this work was to issue clinical practice guidelines on antibiotic prophylaxis in urodynamics (urodynamic studies, UDS).

Materials And Methods: Clinical practice guidelines were provided using a formal consensus method. Guidelines proposals were drew up by a multidisciplinary experts group (pilot group = steering group), then rated by a panel of 12 experts (rating group) using a formal consensus method, and then peer reviewed by a reviewing/reading group of experts (different from the rating group). Read More

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November 2018
4 Reads

Male-female differences in characteristics and early outcomes of patients undergoing tricuspid valve surgery: a national cohort study in the Netherlands.

Eur J Cardiothorac Surg 2018 Dec 4. Epub 2018 Dec 4.

Department of Cardiothoracic Surgery, Erasmus MC, Rotterdam, Netherlands.

Objectives: This study aims to explore male-female differences in baseline and procedural characteristics, and outcomes of patients undergoing isolated or concomitant tricuspid valve (TV) surgery.

Methods: All TV procedures registered between 2007 and 2016 in the database of the Netherlands Association for Cardio-Thoracic Surgery were analysed. Logistic regression analyses with interaction terms were used to determine whether sex was associated with hospital mortality. Read More

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December 2018

Comparative genomics of transport proteins in seven Bacteroides species.

PLoS One 2018 5;13(12):e0208151. Epub 2018 Dec 5.

Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA, United States of America.

The communities of beneficial bacteria that live in our intestines, the gut microbiome, are important for the development and function of the immune system. Bacteroides species make up a significant fraction of the human gut microbiome, and can be probiotic and pathogenic, depending upon various genetic and environmental factors. These can cause disease conditions such as intra-abdominal sepsis, appendicitis, bacteremia, endocarditis, pericarditis, skin infections, brain abscesses and meningitis. Read More

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December 2018
2 Reads

Emergence of a dalbavancin induced glycopeptide/lipoglycopeptide non-susceptible Staphylococcus aureus during treatment of a cardiac device-related endocarditis.

Emerg Microbes Infect 2018 Dec 5;7(1):202. Epub 2018 Dec 5.

Department of Medicine I, Division of Infectious Diseases and Tropical Medicine, Medical University of Vienna, Vienna, Austria.

In the present study, we demonstrated the emergence of dalbavancin non-susceptible and teicoplanin-resistant Staphylococcus aureus small colony variants which were selected in vivo through long-term treatment with dalbavancin. A 36-year-old man presented with a cardiac device-related S. aureus endocarditis and received long-term therapy with dalbavancin. Read More

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December 2018
3 Reads

Bartonella infections in cats and dogs including zoonotic aspects.

Parasit Vectors 2018 Dec 4;11(1):624. Epub 2018 Dec 4.

Departament de Medicina i Cirurgia Animals, Facultat de Veterinària, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.

Bartonellosis is a vector-borne zoonotic disease with worldwide distribution that can infect humans and a large number of mammals including small companion animals (cats and dogs). In recent years, an increasing number of studies from around the world have reported Bartonella infections, although publications have predominantly focused on the North American perspective. Currently, clinico-pathological data from Europe are more limited, suggesting that bartonellosis may be an infrequent or underdiagnosed infectious disease in cats and dogs. Read More

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December 2018

Antimicrobial Susceptibilities of Oral Isolates of and According to the Consensus Guidelines for Fastidious Bacteria.

Medicines (Basel) 2018 Dec 3;5(4). Epub 2018 Dec 3.

Department of Microbiology, St. Marianna University School of Medicine, Kawasaki, Kanagawa 216-8511, Japan.

The genera and , previously known as nutritionally variant streptococci (NVS), are fastidious bacteria requiring vitamin B₆ analogs for growth. They are members of human normal oral microbiota, and are supposed to be one of the important pathogens for so-called "culture-negative" endocarditis. The type strains and oral isolates identified, by using both phenotypic profiles and the DNA⁻DNA hybridization method, were examined for susceptibilities to 15 antimicrobial agents including penicillin (benzylpenicillin, ampicillin, amoxicillin, and piperacillin), cephem (cefazolin, ceftazidime, ceftriaxone, and cefaclor), carbapenem (imipenem), aminoglycoside (gentamicin), macrolide (erythromycin), quinolone (ciprofloxacin), tetracycline (minocycline), glycopeptide (vancomycin), and trimethoprim-sulfamethoxazole complex. Read More

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December 2018

Apport des nouvelles recommandations pour la prise en charge de l’endocardite infectieuse.

Rev Prat 2017 Feb;66(2):183-190

Service des maladies infectieuses et tropicales, CHU de Pointe-à-Pitre/Abymes, Les Abymes, Guadeloupe, France.

Contribution of the new guidelines for the management of infective endocarditis. New guidelines for the management of infective endocarditis (IE) have been recently published both in United States and in Europe. Although identification responsible micro-organism by blood culture and assessment of cardiac lesions by echocardiography remain the cornerstone of the diagnosis of IE, recommendations insist on the additive interest of multimodality imaging including cerebral MRI, MSCT and nuclear imaging (Pet CT) in the diagnosis of both cardiac and extracardiac lesions of IE. Read More

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February 2017
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Infective endocarditis complicated with nonobstructive ST elevation myocardial infarction related to septic embolism with intracranial hemorrhage: A case report.

Medicine (Baltimore) 2018 Nov;97(48):e13089

Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital.

Rationale: Infective endocarditis (IE) complicated with obstructive ST elevation myocardial infarction (STEMI) has been reported in the literature and which were mostly related to coronary artery embolism, obstruction, or compression. However, there has been no reported case discussing about IE complicated with nonobstructive STEMI.

Patient Concerns: In this report, we report a 38-year-old female suffering from intermittent fever and was later diagnosed as IE. Read More

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November 2018
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Difference in Outcome Following Surgery for Native Aortic and Mitral Valve Infective Endocarditis.

Thorac Cardiovasc Surg 2018 Nov 30. Epub 2018 Nov 30.

Department of Cardiothoracic Surgery, Skane University Hospital and Lund University, Lund, Sweden.

Background:  We investigated differences in clinical presentation, microbiology, and short- and long-term results according to the affected valve in patients who underwent surgery for left-sided native valve infective endocarditis (IE).

Methods:  This was a single-center retrospective study of 117 patients with isolated mitral valve IE (group M) and 140 patients with isolated aortic valve IE (group A) who underwent surgery between 1998 and 2015.

Results:  The mean age of patients in group M was 62 ± 14 years, whereas in group A the patients were 56 ± 14 years old ( = 0. Read More

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November 2018
7 Reads

Correlation between Streptococcus bovis bacteremia and density of cows in Galicia, northwest of Spain.

Infection 2018 Nov 29. Epub 2018 Nov 29.

Infectious Diseases Unit, Hospital Universitario Lucus Augusti, Lugo, Spain.

Background: There are few data on the epidemiology of infections caused by Streptococcus bovis (Sb). Some studies suggest that both residence in rural areas and contact with livestock could be potential risk factors.

Methods: We performed a retrospective study for the period 2005-2016 of all cases of bacteremia caused by Sb in Galicia (a region in the northwest of Spain). Read More

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November 2018
1 Read

Endocarditis After Transcatheter Pulmonary Valve Replacement.

J Am Coll Cardiol 2018 Dec;72(22):2717-2728

German Heart Center Munich, Munich, Germany.

Background: Endocarditis has emerged as one of the most concerning adverse outcomes in patients with congenital anomalies involving the right ventricular outflow tract (RVOT) and prosthetic valves.

Objectives: The aim of this study was to evaluate rates and potential risk factors for endocarditis after transcatheter pulmonary valve replacement in the prospective Melody valve trials.

Methods: All patients in whom a transcatheter pulmonary valve (TPV) was implanted in the RVOT as part of 3 prospective multicenter studies comprised the analytic cohort. Read More

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December 2018
1 Read

Multispacer sequence typing of Coxiella burnetii DNA from removed prosthetic heart valve material discloses first human case of infective endocarditis caused by MST_18.

Int J Infect Dis 2018 Nov 26. Epub 2018 Nov 26.

Department of Clinical Microbiology, Aarhus University Hospital,Palle-Juul Jensens Boulevard 99, DK-8200 Aarhus N.

Introduction: In Denmark, Q fever was previously considered a rare and imported disease, but recent testing of antibodies in cattle as well as humans has indicated that the infection is widespread. A 76-year old Danish man was diagnosed with infective endocarditis and underwent open surgical aortic valve replacement with insertion of a biologic valve. Due to paravalvular leakage, destruction of the aortic annulus, and an aortic root abscess, the patient was re-operated three weeks later with replacement of the biologic valve and insertion of an aortic prosthetic tube. Read More

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November 2018
1 Read

Cardiac Computed Tomography of Aortic Infective Endocarditis.

QJM 2018 Nov 28. Epub 2018 Nov 28.

Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kitaku, Okayama, Japan.

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November 2018

Bilateral watershed infarcts in infective endocarditis.

QJM 2018 Nov 28. Epub 2018 Nov 28.

Department of Medicine, Geriatrics, Ng Teng Fong General Hospital, Singapore.

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November 2018
1 Read

Beyond the clinical impact of aortic and pulmonary valve implantation: health-related quality of life, informal care and productivity.

Eur J Cardiothorac Surg 2018 Nov 27. Epub 2018 Nov 27.

Institute for Medical Technology Assessment, Erasmus University, Rotterdam, Netherlands.

Objectives: Our aim was to provide estimates of patient-reported health-related quality of life (HRQoL), use of informal care and productivity in patients after surgical aortic and pulmonary valve replacement and transcatheter aortic valve implantation.

Methods: Consecutive cohorts of 1239 adult patients who had surgical aortic valve replacement or surgical pulmonary valve replacement and 433 patients who had transcatheter aortic valve implantation at 2 Dutch heart centres were cross-sectionally surveyed at a median time of 2.9 and 3. Read More

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November 2018

Embolization of Endocardial Vegetation With Stroke Presentation.

Am J Forensic Med Pathol 2018 Nov 27. Epub 2018 Nov 27.

Department of Biomedical Sciences, University of South Carolina School of Medicine Greenville, Greenville, SC.

This case report details the unique cause of death of a 37-year-old Caucasian woman with a history significant for intravenous drug abuse. Before her death, she complained of extremity weakness and pain. Although her death was discovered to be the result of endocarditis, her symptoms were similar to that of a stroke. Read More

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November 2018
3 Reads

Staphylococcus aureus endocarditis associated with injecting new psychoactive substances.

J R Coll Physicians Edinb 2018 Dec;48(4):304-310

Royal Infirmary of Edinburgh, Edinburgh, UK.

Background: Staphylococcus aureus infective endocarditis (IE) associated with injection of new psychoactive substances (NPS) in Edinburgh from 2014 to 2016 was observed. We compared these infections with a series of S. aureus IE cases in a non-injecting population within Edinburgh. Read More

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December 2018
2 Reads

Epidemiology of Whipple's Disease in the USA Between 2012 and 2017: A Population-Based National Study.

Dig Dis Sci 2018 Nov 28. Epub 2018 Nov 28.

Department of Internal Medicine and Division of Gastroenterology and Liver Disease, University Hospitals Cleveland Medical Center, Case Western Reserve University, 11100 Euclid Avenue, Wearn 244, Cleveland, OH, 44106, USA.

Objective: Prior studies on the epidemiology of Whipple's disease are limited by small sample size and case series design. We sought to characterize the epidemiology of Whipple's disease in the USA utilizing a large population-based database.

Methods: We queried a commercial database (Explorys Inc, Cleveland, OH), an aggregate of electronic health record data from 26 major integrated healthcare systems in the USA. Read More

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November 2018

Infective Endocarditis in the Elderly: Diagnostic and Treatment Options.

Drugs Aging 2018 Nov 29. Epub 2018 Nov 29.

Department of Cardiology, St Thomas' Hospital, Westminster Bridge Road, London, SE1 7EH, UK.

Infective endocarditis (IE) is an uncommon, life-threatening systemic disorder with significant morbidity and persistently high mortality. The age of the peak incidence of IE has shifted from 45 years in the 1950s to 70 years at the present time, and elderly people have a five-fold higher risk of IE than the general adult population. Elderly IE patients demonstrate a higher prevalence of coagulase-negative staphylococci, enterococci and Streptococcus bovis, and lower rates of infection by viridans group streptococci. Read More

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November 2018
1 Read

Evaluation of Strategies in the Management of Infective Aortic Valve Endocarditis at German Cardiac Surgical Departments.

Thorac Cardiovasc Surg 2018 Nov 28. Epub 2018 Nov 28.

Department of Cardiac Surgery, Heart Centre, University of Leipzig, Leipzig, Germany.

Background:  Surgical treatment of infective aortic valve endocarditis (AVE) remains a therapeutic challenge, necessitating interdisciplinary approach to limit morbidity and mortality in this high-risk cohort. With a considerable spectrum of available laboratory testings, imaging techniques, as well as operative strategies developed in recent years, there is a lack of standardization across cardiac surgical departments in Germany. Thus, the optimal treatment strategy of AVE has yet to be defined. Read More

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November 2018

Stroke in Patients with Infective Endocarditis: A 15-Year Single-Center Cohort Study.

Eur Neurol 2018 Nov 28;80(3-4):171-178. Epub 2018 Nov 28.

Department of Neurology, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, China.

Objective: To explore the relationship between infective endocarditis (IE) and stroke.

Methods: The clinical data of patients diagnosed with IE from January 2003 to December 2017 in Beijing Anzhen Hospital Affiliated to Capital Medical University were retrospectively analyzed.

Results: A total of 861 patients (mean age: 40. Read More

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November 2018
2 Reads

Mitral valve prolapse.

Expert Rev Cardiovasc Ther 2018 Nov 28. Epub 2018 Nov 28.

a Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust , London , UK.

Introduction: Mitral valve prolapse is a common valve pathology with a spectrum of disease from isolated prolapse to myxomatous, multi-scallop Barlow's disease. The main complications relate to progression of mitral regurgitation, endocarditis, sudden death and stroke. The timing of intervention in patients with asymptomatic severe mitral regurgitation is controversial. Read More

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November 2018
1 Read

Early surgery with aggressive surgical approach to improve 6-month outcomes in patients with active infective endocarditis: contribution of cerebral preoperative magnetic resonance imaging.

Gen Thorac Cardiovasc Surg 2018 Nov 27. Epub 2018 Nov 27.

Departments of Cardiology, Sapporo City General Hospital, Sapporo, Japan.

Objectives: We investigated the hypothesis that early surgery for infective endocarditis (IE) attenuates the rate of death or embolic events and does not increase the rate of relapse or postoperative valvular dysfunction (PVD) at 6 months.

Methods: 21 consecutive patients who underwent surgical treatment of IE were prospectively included. We assessed 6-month postoperative clinical outcomes by comparing early surgery (Group E, surgery within 72 h) and conventional treatment (Group C). Read More

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November 2018

Asunaprevir and daclatasvir in hemodialysis patients with chronic hepatitis C virus genotype 1b infection.

JGH Open 2017 Dec 28;1(4):148-152. Epub 2017 Nov 28.

Department of Internal Medicine, Division of Hepatology Saga University Hospital Saga Japan.

Background And Aim: Patients requiring hemodialysis show high morbidity with hepatitis C virus (HCV) infection, but there are difficulties associated with interferon-based therapies. Asunaprevir and daclatasvir could help patients with HCV genotype 1b because the drugs have a nonrenal metabolism and show good viral eradication. We evaluated the efficacy and safety of combined asunaprevir and daclatasvir therapy. Read More

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December 2017

Severity of presentation, not sex, increases risk of surgery for infective endocarditis (Commentary).

Ann Thorac Surg 2018 Nov 24. Epub 2018 Nov 24.

Structural Heart and Valve Center, Division of Cardiovascular Surgery, Emory University School of Medicine, 550 Peachtree Street NE, 6(th) Floor Atlanta, GA 30308. Electronic address:

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November 2018
1 Read

Intracolonic cardiac pacemaker: A case of device migration with colon perforation out of a subcutaneous epifascial pocket.

HeartRhythm Case Rep 2018 Nov 22;4(11):497-500. Epub 2018 Apr 22.

Division of Cardiology, Heart Center Lucerne, Luzerner Kantonsspital, Lucerne, Switzerland.

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November 2018
1 Read

Severity of presentation, not sex, increases risk of surgery for infective endocarditis.

Ann Thorac Surg 2018 Nov 23. Epub 2018 Nov 23.

Department of Cardiothoracic Surgery, Heart Center of the University of Cologne, Cologne, Germany.

Background: Cardiac surgery for infective endocarditis (IE) is associated to substantial short- and long-term mortality and female sex seems to be associated with even worse outcomes. The aim of our study was to analyze the impact of sex on 30-day and long-term mortality and to identify sex-related risk factors in IE patients requiring cardiac surgery.

Methods: Relevant clinical data of all consecutive 305 patients undergoing cardiac surgery for IE between 2009-2016 were extracted from our institutional database and retrospectively analyzed. Read More

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November 2018
3 Reads

Long-term performance of pulmonary homografts after the Ross procedure: experience up to 25 years.

Eur J Cardiothorac Surg 2018 Nov 22. Epub 2018 Nov 22.

Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.

Objectives: The aim of this study was to evaluate the long-term durability and function of pulmonary homografts used for right ventricular outflow tract reconstruction in the Ross procedure at a single centre with 25 years of experience.

Methods: The study included 274 patients (212 male patients and 62 female patients; age 3-59 years), who underwent the Ross procedure between 1991 and 2014. Homograft-related complications and reinterventions were assessed. Read More

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November 2018
6 Reads

The Intravenous Drug User with a Big Heart.

Cureus 2018 Sep 18;10(9):e3325. Epub 2018 Sep 18.

Cardiology, Charleston Area Medical Center, Charleston, USA.

Infective endocarditis is a severe and now more frequently encountered condition given the rise of intravenous (IV) drug use. An IV drug user presented with septic shock and bacterial endocarditis. Upon imaging, a fistulous tract was discovered, communicating from the annulus of the infected mitral valve to a large left ventricular pseudoaneurysm (PA). Read More

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September 2018
2 Reads

Association between atopic dermatitis and extra-cutaneous bacterial and mycobacterial infections: A systematic review and meta-analysis.

J Am Acad Dermatol 2018 Nov 21. Epub 2018 Nov 21.

Department of Dermatology, Preventive Medicine and Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL; Northwestern Medicine Multidisciplinary Eczema Center, Chicago, IL. Electronic address:

Background: Atopic dermatitis (AD) is associated with increased bacterial colonization and infection of skin, and multiple risk factors for extra-cutaneous infections. However, previous studies found conflicting results about whether AD is associated with increased extra-cutaneous infections.

Objectives: To determine whether extra-cutaneous bacterial and mycobacterial infections are increased in AD. Read More

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November 2018
3 Reads

Long-term prognosis after surgery for infective endocarditis: Distinction between predictors of early and late survival.

Enferm Infecc Microbiol Clin 2018 Nov 20. Epub 2018 Nov 20.

Cardiac Surgery Department, Ramon y Cajal Hospital, Madrid, Spain.

Objectives: Cardiac surgery is a life-saving procedure in patients diagnosed with infective endocarditis (IE). There are several validated risk scores developed to predict early-mortality; nevertheless, long-term survival has been less investigated. The aim of the present study is to analyze the impact of IE-specific risk factors for early and long-term mortality. Read More

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November 2018
7 Reads

Fifty-seven-year-old man with progressive dyspnoea.

Heart 2018 Nov 22. Epub 2018 Nov 22.

Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia, USA.

Clinical Introduction: A 57-year-old man from the USA with a history of atrial fibrillation and hypertension was evaluated for progressive dyspnoea and decreased energy. The patient denied a history of congestive heart failure, systemic symptoms or myocardial infarction. He was found to have a 3/6 holosystolic murmur radiating to the axilla. Read More

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November 2018
4 Reads

Case of Invasive Streptococcus Dysgalactiae Infection Presenting as Infective Endocarditis with Multiple Brain Embolisms.

Int Heart J 2018 Nov 20. Epub 2018 Nov 20.

Department of the Internal Medicine, Cardiovascular, Respiratory and Neurology Division, Asahikawa Medical University.

A 65-year-old Japanese man complaining of general malaise and presenting with high fever was admitted to our hospital. He had untreated diabetes and hepatocellular carcinoma with liver cirrhosis. Overall findings of the patient indicated sepsis. Read More

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November 2018
2 Reads

Rheumatoid Arthritis-Associated Autoimmunity Due to and Its Resolution With Antibiotic Therapy.

Front Immunol 2018 16;9:2352. Epub 2018 Oct 16.

Division of Rheumatology, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.

() is a Gram-negative coccobacillus recognized as a pathogen in periodontitis and infective endocarditis. By producing a toxin (leukotoxin A, LtxA) that triggers global hypercitrullination in neutrophils, has been recently linked to rheumatoid arthritis (RA) pathogenesis. Although mechanistic and clinical association studies implicate infection in the initiation of autoimmunity in RA, direct evidence in humans is lacking. Read More

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October 2018
4 Reads

Daptomycin Resistant Clinical Strain With Novel Non-synonymous Mutations in the and Genes: A New Insight Into Daptomycin Resistance.

Front Microbiol 2018 6;9:2705. Epub 2018 Nov 6.

Department of Medical Microbiology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.

Daptomycin (DAP) resistance in is uncommon but there are increasing reports of the emergence of resistance during DAP therapy. Most clinical DAP-resistant isolates investigated carried mutations in the gene. The aim of this study was to identify mutations between a clinical pair of methicillin-susceptible (MSSA) isolates (DAP-susceptible and DAP-resistant). Read More

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November 2018
3 Reads

Omphalitis, urachocystitis and septicemia by Streptococcus dysgalactiae in a southern right whale calf Eubalaena australis, Brazil.

Dis Aquat Organ 2018 Nov;131(3):227-232

Setor de Patologia Veterinária, Faculdade de Veterinária (FAVET), Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul (RS) 91540-000, Brazil.

Southern right whales Eubalaena australis (SRW) use the southern coast of Brazil as a wintering and calving ground. Other than anthropogenic threats, there is limited knowledge on health and disease aspects for this species. We report the gross and microscopic findings and microbiological identification of streptococcal septicemia in a SRW calf. Read More

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November 2018
1 Read

Disseminated Spiroplasma apis Infection in Patient with Agammaglobulinemia, France.

Emerg Infect Dis 2018 Dec;24(12):2382-2386

We report a disseminated infection caused by Spiroplasma apis, a honeybee pathogen, in a patient in France who had X-linked agammaglobulinemia. Identification was challenging because initial bacterial cultures and direct examination by Gram staining were negative. Unexplained sepsis in patients with agammaglobulinemia warrants specific investigation to identify fastidious bacteria such as Spiroplasma spp. Read More

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December 2018

[Micra™ leadless pacemaker : Clinical experience and perspectives].

Herzschrittmacherther Elektrophysiol 2018 Dec 19;29(4):334-339. Epub 2018 Nov 19.

Klinik für Kardiologie und Internistische Intensivmedizin, Kepler Universitätsklinikum Linz, Medizinische Fakultät, Johannes Kepler Universität Linz, Altenberger Straße 69, 4040, Linz, Österreich.

Leadless pacemakers have the potential to fundamentally change the field of device therapy. As leads and generator pockets are no longer needed with this technology, many potentially dangerous complications of conventional pacemaker systems like lead fractures, lead endocarditis or pocket infections can be effectively avoided. At present, Micra™ (Medtronic Inc. Read More

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December 2018
1 Read