43,425 results match your criteria Endocarditis


Infective endocarditis due to Staphylococcus aureus in adults with congenital heart disease: The next challenge.

Authors:
Oktay Tutarel

Int J Cardiol 2022 May 18. Epub 2022 May 18.

Department of Congenital Heart Disease and Paediatric Cardiology, German Heart Centre Munich, TUM School of Medicine, Technical University of Munich, Munich, Germany; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany. Electronic address:

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Surgical outcomes of pulmonary valve infective endocarditis: A US population-based analysis.

Int J Cardiol 2022 May 18. Epub 2022 May 18.

Division of Cardiothoracic Surgery, Department of Surgery, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA; Division of Cardiac Surgery, NorthShore University HealthSystem, Chicago, IL, USA. Electronic address:

Background: Pulmonary valve infective endocarditis (PVIE) represents a rare subset of right-sided IE. This study aimed to evaluate the population-level surgical outcomes of PVIE in the United States.

Methods: We performed a retrospective observational study using the 2002-2017 National Inpatient Sample database. Read More

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Outcomes of mitral valve repair in children with infective endocarditis: a single-center experience.

Semin Thorac Cardiovasc Surg 2022 May 17. Epub 2022 May 17.

Department of Cardiac Surgery, Royal Children's Hospital, Melbourne; Department of Paediatrics, University of Melbourne, Melbourne; Heart Research Group, Murdoch Children's Research Institute, Melbourne; Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine, Melbourne. Electronic address:

Background: Mitral valve infective endocarditis (IE) in children is rare, and there are few reports on the outcomes of surgery in these patients. This study investigated the long-term outcomes of mitral valve repair in children with IE.

Methods: Data were retrospectively obtained from medical records and correspondence. Read More

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Streptococcus sanguinis Endocarditis of Bicuspid Aortic Valve Presenting as Septic Arthritis of Lumbar Facet Joint.

Cureus 2022 Apr 16;14(4):e24189. Epub 2022 Apr 16.

Internal Medicine, University of Illinois College of Medicine, Peoria, USA.

Septic arthritis of the facet joint (SAFJ) is an uncommon etiology of low back pain that usually affects the elderly population and immunocompromised patients but is rare in immunocompetent and young patients. When such a clinical presentation occurs, it is imperative to diagnose the source of the infection. We report a case of septic arthritis of the left third and fourth lumbar vertebrae facet joint due to in a young immunocompetent adult, and the source of infection was found to be subacute infective endocarditis of a bicuspid aortic valve which was undiagnosed till now. Read More

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Recurrent Cardioembolic Strokes Due to Marantic Endocarditis As the Initial Presentation of Colorectal Adenocarcinoma.

Cureus 2022 Apr 16;14(4):e24183. Epub 2022 Apr 16.

Neurological Surgery, Boca Raton Regional Hospital, Boca Raton, USA.

Metastases to the brain from primary colorectal carcinoma are rare. Existing literature describing cranial nerve palsy from metastatic colorectal cancer is scattered. To our knowledge, we are the first to describe the combination of CN deficits V, VII, and XII as the initial presentation of colorectal malignancy. Read More

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Optimal surgical strategy for those with aortic valve endocarditis and aortic root abscess.

J Card Surg 2022 May 19. Epub 2022 May 19.

Second Department of Internal Medicine, University of Toyama, Toyama, Japan.

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Diagnosis and Management of Infective Endocarditis in People Who Inject Drugs: JACC State-of-the-Art Review.

J Am Coll Cardiol 2022 May;79(20):2037-2057

Cardiac Surgery Division, Corrigan Minehan Heart Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

The incidence of injection drug use-associated infective endocarditis has been increasing rapidly over the last decade. Patients with drug use-associated infective endocarditis present an increasingly common clinical challenge with poor long-term outcomes and high reinfection and readmission rates. Their care raises issues unique to this population, including antibiotic selection and administration, indications for and ethical issues surrounding surgical intervention, and importantly management of the underlying substance use disorder to minimize the risk of reinfection. Read More

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Effect of Socioeconomic Distress on Risk-Adjusted Mortality after Valve Surgery for Infective Endocarditis.

Semin Thorac Cardiovasc Surg 2022 May 16. Epub 2022 May 16.

Virginia Cardiac Services Quality Initiative, Virginia Beach, VA; Department of Cardiac Surgery, University of Michigan, Ann Arbor, MI. Electronic address:

Objective: Infective endocarditis affects patients of all socioeconomic status. We hypothesized that the Distressed Communities Index (DCI), a comprehensive assessment of socioeconomic status, would be associated with risk-adjusted mortality for patients with endocarditis.

Methods: All patients with endocarditis (2001-2017) in a regional STS database were analyzed. Read More

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Profile, presentation and outcomes of prosthetic valve endocarditis in a South African tertiary hospital: Insights from the Groote Schuur Hospital Infective Endocarditis Registry.

S Afr Med J 2022 Apr 4;112(4):13554. Epub 2022 Apr 4.

Division of Cardiology, Department of Medicine, Faculty of Health Sciences, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.

Background: Prosthetic valve infective endocarditis (PVE) is associated with high morbidity and mortality. The prevalence of PVE in South African retrospective studies ranges between 13% and 17%.

Objectives: To define the clinical profile and outcomes of patients with PVE, and compare them with those of native valve endocarditis (NVE) patients. Read More

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Echocardiographic features of infective endocarditis in South Africa: A prospective cohort study.

S Afr Med J 2022 Apr 30;112(5):321-327. Epub 2022 Apr 30.

Division of Cardiology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa.

Background: Historically, infective endocarditis (IE) in South Africa (SA) was associated with the viridans group of streptococci affecting patients with underlying rheumatic heart disease (RHD). A changing IE bacteriological profile raises the question of whether the profile of underlying valvular abnormality has changed.

Objectives: To investigate the prevalence of underlying structural valve abnormalities and their aetiologies associated with IE in SA, and describe the typical imaging findings. Read More

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Modification of Reconstruction of Left Ventricular Outflow Tract, Aortic Root and the Intervalvular Fibrous Body for Extensive Infective Endocarditis: A Single Center Experience.

Eur J Cardiothorac Surg 2022 May 19. Epub 2022 May 19.

Division of Cardiac Surgery, Heart Centre Siegburg-Wuppertal, University Witten-Herdecke, Germany.

Background: Extensive infective endocarditis stays a serious life-threatening disease with high mortality and morbidity. The aim of this study is to analyze our experience with our modified surgical technique for extensive infective endocarditis during the last 4 years.

Methods: Between March 2017 and February 2021, all patients with extensive infective endocarditis required our modified technique consisting of a radical surgical resection of all infected cardiac tissues, the replacement of infected valves, and a reconstruction of the intervalvular fibrous body, the aortic root and the left ventricular outflow tract with modified elephant trunk were included in this study. Read More

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Septic Pulmonary Embolism Related to Right-sided Infective Endocarditis.

J Saudi Heart Assoc 2022 18;34(2):70-71. Epub 2022 Apr 18.

Department of Cardiology, Bahrain Defence Force Royal Medical Service, Mohammed Bin Khalifa Cardiac Centre (MKCC), Riffa, Kingdom of Bahrain.

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Surgical Correction of a Complex Aorto-Mitral Pathology.

J Saudi Heart Assoc 2022 19;34(2):72-76. Epub 2022 Apr 19.

Department of Cardiovascular Surgery, University of Health Sciences, Gülhane Training and Research Hospital, Ankara 06010, Turkey.

Pseudoaneurysm of mitral-aortic intervalvular fibrosa is a rare entity related to mostly infective endocarditis and surgical trauma of aortic valve. Its diagnosis may be missed following trans-thoracic echocardiographic assessment. Therefore, further imaging investigation such as transesophageal echocardiography and computed tomographic angiography may play a key diagnostic role. Read More

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: Rare case of automatic implantable cardioverter-defibrillator (AICD) lead infection.

SAGE Open Med Case Rep 2022 13;10:2050313X221099367. Epub 2022 May 13.

Department of Internal Medicine, Keesler Medical Center, Keesler Air Force Base, Biloxi, MS, USA.

We present a rare case of automated implantable cardioverter defibrillator (AICD) lead infection. Gemella species are catalase-negative, facultative anaerobic, Gram-positive cocci which are found in normal human oral flora. Gemella are often incorrectly identified on routine Gram stain and culture, requiring advanced techniques such as PCR. Read More

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Lessons of the month 1: Mesenteric ischaemia secondary to infective endocarditis.

Clin Med (Lond) 2022 May;22(3):282-284

Wexham Park Hospital, Slough, UK

A 60-year-old woman presented with sudden-onset epigastric pain, vomiting and small volume rectal bleeding. She had a history of mechanical mitral valve replacement, for which she was on warfarin. Computed tomography (CT) angiography of the abdomen showed gallstones, a fluid-filled stomach and faecal loading. Read More

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Aortic valve repair versus mechanical valve replacement for root aneurysm: The CAVIAAR Multicentric Study.

Eur J Cardiothorac Surg 2022 May 18. Epub 2022 May 18.

APHP, Département de la Recherche Clinique et du Développement (DRCD) Groupement Interrégional de Recherche Clinique et d'Innovation-GIRCI Ile-de-France Hôpital Saint Louis.

Aims: Despite growing evidence that aortic valve repair improves long-term patient outcomes and quality of life, aortic valves are mostly replaced. We evaluate the effect of aortic valve repair versus replacement in patients with dystrophic aortic root aneurysm up to 4 years.

Methods: The multicentric CAVIAAR prospective cohort study enrolled 261 patients: 130 underwent standardized aortic valve repair (REPAIR) consisting of remodelling root repair with expansible aortic ring annuloplasty, and 131 received mechanical composite valve and graft replacement (REPLACE). Read More

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Cardiac calcified amorphous tumor with mitral valve perforation: A case report.

J Cardiol Cases 2022 May 3;25(5):297-299. Epub 2022 Jan 3.

Department of Cardiovascular Surgery, Osaka Police Hospital, Kitayama-cho 10-31, Tennouji-ku, Osaka 543-0035, Japan.

Cardiac calcified amorphous tumors are rare non-neoplastic intracavitary masses. Herein, we report a case of a 75-year-old woman who presented with dyspnea on exertion and multiple cerebral infarctions 3 months prior. Transthoracic echocardiography showed severe mitral regurgitation from the posterior mitral leaflet with valve perforation and severe mitral annular calcification. Read More

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Ruptured sinus of Valsalva aneurysm due to Infective Endocarditis managed by device closure - a case report.

J Cardiol Cases 2022 May 8;25(5):292-296. Epub 2021 Dec 8.

Department of Cardiology, NRS Medical College and Hospital, Kolkata, India.

Ruptured sinus of Valsalva aneurysm (RSOV) is an uncommon cause of high output heart failure. RSOV most commonly opens into the right ventricle followed by the right atrium and non-coronary cusp involvement is relatively uncommon. Infective endocarditis (IE) is a rare cause of RSOV. Read More

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Infective endocarditis caused by from sinusitis: A case report.

J Cardiol Cases 2022 May 8;25(5):279-281. Epub 2021 Dec 8.

Department of Cardiovascular Medicine, Shinshu University Hospital, Matsumoto, Japan.

Since the advent of the pneumococcal vaccine, cases of infective endocarditis (IE) from have become rare. Pneumococcal endocarditis (PE) may be the initial presentation in Austrian syndrome, which is very lethal. PE needs early detection and treatment and more commonly develops from pneumonia. Read More

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Sleep patterns and potential risk factors for disturbed sleep quality in patients after surgery for infective endocarditis.

J Cardiothorac Surg 2022 May 17;17(1):121. Epub 2022 May 17.

Department of Comprehensive Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong Province, China.

Background: The current study aimed to investigate the sleep quality of patients after valve replacement surgery due to infective endocarditis and identify risk factors for disturbed sleep post hospitalisation.

Methods: Eighty patients were assessed postoperatively using subjective scale measures, the Pittsburgh sleep quality index (PSQI) and the Epworth sleepiness scale, and an objective measure, actigraphy. Scale measures were assessed approximately 2 weeks and 6 months after surgery. Read More

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Sensitivity, specificity and predictive values of ICD-10 substance use codes in a cohort of substance use-related endocarditis patients.

Am J Drug Alcohol Abuse 2022 May 17:1-10. Epub 2022 May 17.

Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.

Background: Healthcare databases have the potential to become efficient tools for epidemiological research in People Who Inject Drugs (PWID). The validity of ICD-10 codes for specific substances in this population has not been assessed.

Objectives: Validate ICD-10 diagnosis codes relating to the use of specific substance classes in a cohort of endocarditis patients. Read More

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[Endocarditis complicated by anterior myocardial infarction: a case report. What the guidelines do not say].

G Ital Cardiol (Rome) 2022 May;23(5):336-339

Dipartimento di Cardiologia, Azienda Ospedaliera dei Colli - Ospedale "Monaldi", Napoli.

Acute myocardial infarction is an uncommon complication of infective endocarditis, burdened by high mortality and often underdiagnosed. Due to its reduced frequency, current guidelines do not always highlight this condition or provide clear indications regarding treatment. We present a case of acute coronary syndrome induced by the occlusion of the anterior descending artery, due to a septic embolus and treated by aspiration of the embolic material. Read More

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Dalbavancin as an option for treatment of S. aureus bacteremia (DOTS): study protocol for a phase 2b, multicenter, randomized, open-label clinical trial.

Trials 2022 May 16;23(1):407. Epub 2022 May 16.

Division of Infectious Diseases, Duke University School of Medicine, Durham, NC, USA.

Background: Staphylococcus aureus bacteremia is a life-threatening infection and leading cause of infective endocarditis, with mortality rates of 15-50%. Treatment typically requires prolonged administration of parenteral therapy, itself associated with high costs and potential catheter-associated complications. Dalbavancin is a lipoglycopeptide with potent activity against Staphylococcus and a long half-life, making it an appealing potential therapy for S. Read More

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Clinical outcomes of bileaflet St. Jude Medical and tilting disc TTK Chitra mechanical heart valve prosthesis: A comparative study.

J Card Surg 2022 May 16. Epub 2022 May 16.

Department of Cardiology, Sreechitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.

Background: Comparative data on the clinical outcomes of TTK Chitra mechanical heart valve prosthesis (CHVP), an indigenously developed low-cost tilting disc valve and commonly used bileaflet valve, the St. Jude medical (SJM) prosthesis are sparse.

Methods: We conducted a retrospective follow-up study of consecutive patients undergoing mitral (MVR) and aortic valve replacement (AVR) with SJM or CHVP mechanical prostheses over a 6-year period at our institution. Read More

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Biomarker of neutrophil extracellular traps is associated with deep-seated infections and predicts mortality and cardiovascular morbidity in commensal streptococcal bacteremia.

J Microbiol Immunol Infect 2022 May 2. Epub 2022 May 2.

Department of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. Electronic address:

Background: Neutrophil extracellular traps (NETs) play important roles in sepsis and deep-seated infections, but whether NET formation correlates with clinical outcomes of patients with streptococcal bloodstream infections (BSIs) is unclear.

Methods: We analyzed serum levels of complexes of myeloperoxidase and DNA (MPO-DNA) in patients with streptococcal-BSIs. In vitro assay of NET induction by serum from BSI patients was performed. Read More

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Pacemaker-induced endocarditis by Gordonia bronchialis.

Enferm Infecc Microbiol Clin (Engl Ed) 2022 May;40(5):255-257

Servicio de Microbiología, Hospital Universitario Miguel Servet Zaragoza, Spain.

Purpose: Gordonia species are known to be opportunistic human pathogens causing secondary infections. We present the second case in the world of endocarditis caused by Gordonia bronchialis and a review of all the cases of endocarditis caused by Gordonia spp.

Methods: The identification was performed by matrix-assisted desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and 16S rRNA gene sequencing were performed to confirm the identification. Read More

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Aortic root replacement: What's in your wallet?

Eur J Cardiothorac Surg 2022 May 16. Epub 2022 May 16.

Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh.

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Left ventricular free-wall rupture: An unusual presentation of non-bacterial thrombotic endocarditis.

Perfusion 2022 May 16:2676591221092313. Epub 2022 May 16.

Department of Cardiac Surgery, Glenfield Hospital, Leicester, UK.

Non-bacterial thrombotic endocarditis (NBTE) is a rare, often asymptomatic, condition. A 55-year-old woman presented with hemiparesis, facial palsy and chest pain. After urgent investigation, she was referred as a case of type A aortic dissection complicated by tamponade, myocardial infarction and stroke. Read More

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