37,991 results match your criteria Endocarditis


[Infective Endocarditis in Right Ventricle( RV)-Pulmonary Artery( PA) Conduit Late after the Ross Procedure;Report of a Case].

Kyobu Geka 2019 Feb;72(2):156-159

Department of Cardiovascular Surgery, Seirei Hamamatsu General Hospital, Hamamatsu, Japan.

Ross procedure has been found to have a lower incidence of infective endocarditis compared to other aortic replacement procedure using prosthetic valves. We report a case of 25-year-old man who underwent Ross procedure for congenital aortic stenosis and regurgitation when he was 7 years old. He presented with fever and was highly suspected of infective endocarditis. Read More

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February 2019

A pediatric case of Staphylococcus lugdunensis-induced infective endocarditis at bovine jugular vein.

Ann Thorac Surg 2019 Feb 13. Epub 2019 Feb 13.

Department of cardiovascular surgery, Mt. Fuji Shizuoka children's hospital, Shizuoka, Japan.

A 2-year-old boy underwent right ventricular outflow tract reconstruction (RVOTR) with a bovine jugular vein graft. He presented with high fever on postoperative day 6. Blood and drainage effusion cultures were all positive for S. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2019.01.028DOI Listing
February 2019

Factors associated with readmission and mortality in adult patients with skin and soft tissue infections.

Int J Dermatol 2019 Feb 15. Epub 2019 Feb 15.

Clinical Microbiology Department, Son Llàtzer Hospital, Balearic Islands, Spain.

Background: Skin and soft tissue infections (SSTIs) are a common cause of consultation, and complicated cases require hospitalization. We describe factors that are related to readmission and/or mortality of hospitalized patients diagnosed with SSTIs.

Methods: Retrospective review of hospital-admitted patients with a diagnosis of cellulitis, abscess, hidradenitis, fasciitis, and Fournier's gangrene. Read More

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http://dx.doi.org/10.1111/ijd.14390DOI Listing
February 2019

[Microflora of peripheral blood obtained from patients with infective endocarditis.]

Klin Lab Diagn 2018 ;63(10):636-640

The Federal State Budget Scientific Institution «Research Institute for Complex Issues of Cardiovascular Diseases», 650002, Kemerovo, Russia.

Infective endocarditis is a serious inflammatory disease associated with damage of heart valves and other parts of endocardium. This study included 91 patients with a confirmed diagnosis of «infectious endocarditis» and hospitalized at the Research Institute of Complex Problems of Cardiovascular Disease (Kemerovo, Russia) from 2010 to 2015. The determination of the spectrum of microorganisms in the samples of patients' peripheral blood was carried out using the PCR method using reagents produced by Lyteh Ltd. Read More

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http://dx.doi.org/10.18821/0869-2084-2018-63-10-636-640DOI Listing
January 2018

Destructive aortic root endocarditis involving pulmonary valve with aorto-right ventricular fistula.

Interact Cardiovasc Thorac Surg 2019 Feb 14. Epub 2019 Feb 14.

Department of Thoracic, Cardiovascular and General Surgery, Kanazawa University, Kanazawa, Japan.

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http://dx.doi.org/10.1093/icvts/ivz025DOI Listing
February 2019

Fundamental role of echocardiographic evaluation in the diagnosis of prosthetic valve endocarditis.

Echocardiography 2019 Feb 15. Epub 2019 Feb 15.

Department of Cardiology, Kosuyolu Kartal Heart Training and Research Hospital, Istanbul, Turkey.

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http://dx.doi.org/10.1111/echo.14287DOI Listing
February 2019

Recurrent myocardial infarction in a 50-year-old woman.

Heart 2019 Feb 14. Epub 2019 Feb 14.

University Hospital Hairmyres, East Kilbridge, UK.

CLINICAL INTRODUCTION: A 50-year-old woman presented with an inferoposterior ST-elevation myocardial infarction (STEMI) and underwent emergency percutaneous coronary intervention (PCI). Angiography revealed acute occlusion of the circumflex and right coronary (RCA) arteries. PCI was uncomplicated. Read More

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http://heart.bmj.com/lookup/doi/10.1136/heartjnl-2018-314114
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http://dx.doi.org/10.1136/heartjnl-2018-314114DOI Listing
February 2019
1 Read

Neutrophil to Lymphocyte Ratio and Mortality in Spinal Epidural Abscess.

Spine J 2019 Feb 11. Epub 2019 Feb 11.

Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School. Electronic address:

Background Context: Neutrophil to lymphocyte ratio and platelet to lymphocyte ratio have been previously identified as markers for overall survival in oncology but remain heretofore unexplored in spinal epidural abscess (SEA).

Purpose: The purpose of this study was to determine the impact of these routinely collected assessments on ninety-day mortality in SEA.

Study Design/setting: Retrospective, case-control study PATIENT SAMPLE: Patients 18 years or older diagnosed with SEA at two academic medical centers and three community hospitals OUTCOME MEASURES: Ninety-day post-discharge and in-hospital mortality METHODS: Complete blood count with differential obtained on the day immediately preceding or on the day of admission was used to calculate platelet to lymphocyte and neutrophil to lymphocyte ratios. Read More

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http://dx.doi.org/10.1016/j.spinee.2019.02.005DOI Listing
February 2019

Drug Rash with Eosinophilia and Systemic Symptoms Syndrome Presenting After the Initiation of Staphylococcus hominis Infectious Endocarditis Treatment: A Case Report and Updated Review of Management Considerations.

Cureus 2018 Dec 4;10(12):e3679. Epub 2018 Dec 4.

Internal Medicine, University of Central Florida College of Medicine, Orlando, USA.

We present the case of a 62-year-old Caucasian man who was being treated for mitral valve endocarditis via a six-week course of vancomycin. On Day 32 of the treatment, he developed an erythematous, pruritic, desquamating, and painful rash covering 80% of the total body surface area and intermittent fevers. Laboratory findings included leukocytosis with peripheral blood eosinophilia and elevated erythrocyte sedimentation rate, C-reactive protein, and serum creatinine. Read More

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http://dx.doi.org/10.7759/cureus.3679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367119PMC
December 2018
2 Reads

Bicuspid Aortic Valve: An Update in Morphology, Genetics, Biomarker, Complications, Imaging Diagnosis and Treatment.

Front Physiol 2018 30;9:1921. Epub 2019 Jan 30.

Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

The bicuspid aortic valve, a kind of heart disease that comes from parents, has been paid attention around the world. Although most bicuspid aortic valve (BAV) patients will suffer from some complications including aortic stenosis, aortic regurgitation, endocarditis, and heart dysfunction in the late stage of the disease, there is none symptom in the childhood, which restrains us to diagnose and treatment in the onset phase of BAV. Hemodynamic abnormalities induced by the malformations of the valves in BAV patients for a long time will cause BAV-associated aortopathy: including progress aortic dilation, aneurysm, dissection and rupture, cardiac cyst and even sudden death. Read More

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https://www.frontiersin.org/article/10.3389/fphys.2018.01921
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http://dx.doi.org/10.3389/fphys.2018.01921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363677PMC
January 2019
7 Reads

Methicillin-Resistant Staphylococcus aureus Prosthetic Valve Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management.

Clin Microbiol Rev 2019 Mar 13;32(2). Epub 2019 Feb 13.

Division of Infectious Diseases, Medicine Department, Massachusetts General Hospital, Boston, Massachusetts, USA.

SUMMARY prosthetic valve endocarditis (PVE) remains among the most morbid bacterial infections, with mortality estimates ranging from 40% to 80%. The proportion of PVE cases due to methicillin-resistant (MRSA) has grown in recent decades, to account for more than 15% of cases of PVE and 6% of all cases of PVE. Because no large studies or clinical trials for PVE have been published, most guidelines on the diagnosis and management of MRSA PVE rely upon expert opinion and data from animal models or related conditions (e. Read More

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http://dx.doi.org/10.1128/CMR.00041-18DOI Listing

Utility of qSOFA score in identifying patients at risk for poor outcome in Staphylococcus aureus bacteremia.

BMC Infect Dis 2019 Feb 13;19(1):149. Epub 2019 Feb 13.

Department of Clinical Pharmacy, University of Southern California School of Pharmacy, 1985 Zonal Ave, Los Angeles, CA, 90089, USA.

Background: The prognostic capability of the quick Sequential Organ Failure Assessment (qSOFA) bedside scoring tool is uncertain in non-ICU patients with sepsis due to bacteremia given the low number of patients previously evaluated.

Methods: We performed a retrospective cohort study of adult hospitalized patients with Staphylococcus aureus bacteremia (SAB). Medical charts were reviewed to determine qSOFA score, systemic inflammatory response syndrome (SIRS) criteria, and Pitt bacteremia score (PBS) at initial presentation; their predictive values were compared for ICU admission within 48 h, ICU stay duration > 72 h, and 30-day mortality. Read More

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http://dx.doi.org/10.1186/s12879-019-3770-4DOI Listing
February 2019

Successful cure of daptomycin-non-susceptible, vancomycin-intermediate Staphylococcus aureus prosthetic aortic valve endocarditis directed by synergistic in vitro time-kill study.

Infect Dis (Lond) 2019 Feb 14:1-6. Epub 2019 Feb 14.

d Department of Pharmacy , Veterans Administration Western New York Healthcare System , Buffalo , NY , USA.

Infectious complications following surgical valve replacements are extremely difficult to treat, often requiring prolonged antimicrobials therapy with or without surgery. Vancomycin-intermediate Staphylococcus aureus is an infrequent pathogen, with an estimated prevalence of less than 0.3%, but presents even greater challenges. Read More

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http://dx.doi.org/10.1080/23744235.2018.1533646DOI Listing
February 2019

Bioprosthetic Aortic Valve Replacement in Nonelderly Adults.

Circ Cardiovasc Qual Outcomes 2019 Feb;12(2):e005481

Department of Cardiothoracic Surgery (J.R.G.E., S.A.H., P.G., B.P., G.P., A.J.J.C.B., J.J.M.T.), Erasmus University Medical Center, Rotterdam, The Netherlands.

Background To support decision-making in aortic valve replacement in nonelderly adults, we aim to provide a comprehensive overview of reported outcome after bioprosthetic aortic valve replacement and to translate this to age-specific patient outcome estimates. Methods and Results A systematic review was conducted for papers reporting clinical outcome after aortic valve replacement with currently available bioprostheses in patients with a mean age <55 years, published between January 1, 2000, and January 9, 2016. Pooled reported event rates and time-to-event data were pooled and entered into a microsimulation model to calculate life expectancy and lifetime event risk for the ages of 25, 35, 45, and 55 years at surgery. Read More

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http://dx.doi.org/10.1161/CIRCOUTCOMES.118.005481DOI Listing
February 2019

Infective endocarditis in two patients with pemphigus vulgaris under multiagent immunosuppressive drug therapy: a rare entity to remember in the differential diagnosis of fever of unknown origin.

Dermatol Ther 2019 Feb 13:e12860. Epub 2019 Feb 13.

Department of Dermatology and Venereology, Istanbul Faculty of Medicine, Istanbul University, Istanbul.

Pemphigus vulgaris (PV) is an autoimmune blistering skin disease that, may require multiagent immunosuppressive drug therapies in severe cases. In addition to the well established corticosteroid sparing agents azathioprine, mycophenolate mofetil, and methotrexate, rituximab is being increasingly used alone or in combination in the management of PV. Due to the chronic course of the disease, the cumulative effects of these therapy agents over long follow-up periods may result in various adverse reactions, including bacterial and viral infections. Read More

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http://dx.doi.org/10.1111/dth.12860DOI Listing
February 2019

An Unusual Case of Tricuspid Stenosis.

Eur J Case Rep Intern Med 2018 24;5(4):000836. Epub 2018 Apr 24.

Internal Medicine Department, Centro Hospitalar de São João, Porto, Portugal.

Tricuspid stenosis is an uncommon valvular abnormality commonly associated with other valvular lesions. Ebstein's anomaly is a rare congenital heart malformation characterized primarily by abnormalities of the tricuspid valve and right ventricle. Endomyocardial fibrosis is a restrictive cardiomyopathy observed in tropical and subtropical regions. Read More

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http://dx.doi.org/10.12890/2018_000836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346752PMC

Successful Management of Prosthetic Valve Endocarditis with Antibiotherapy Alone.

Eur J Case Rep Intern Med 2018 24;5(4):000808. Epub 2018 Apr 24.

Internal Medicine Service, Centro Hospitalar Tondela-Viseu, E.P.E. - Viseu, Portugal.

Objectives: To report a case of mechanical aortic prosthesis endocarditis successfully treated with antibiotics alone.Materials and methods: We describe a clinical case and present a review of the literature.

Results: A 60-year-old female farmer with a mechanical aortic prosthetic valve presented with low back pain and fever. Read More

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http://dx.doi.org/10.12890/2018_000808DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346756PMC

The Full Spectrum of Infective Endocarditis: Case Report and Review.

Case Rep Cardiol 2019 10;2019:7257401. Epub 2019 Jan 10.

Department of Cardiovascular Diseases, University of Kansas Medical Center, Kansas City, KS, USA.

Over the past five decades, the incidence of intravenous drug use- (IVDU-) associated infective endocarditis (IE) has been on the rise in North America. Classically, IVDU has been thought to affect right-sided valves. However, in recent times a more variable presentation of IVDU-associated IE has been reported. Read More

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http://dx.doi.org/10.1155/2019/7257401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348878PMC
January 2019

Contemporary management of cardiac implantable electronic device infection.

Heart 2019 Feb 12. Epub 2019 Feb 12.

Department of Cardiovascular Diseases, Mayo Clinic Arizona, Phoenix, Arizona, USA.

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http://heart.bmj.com/lookup/doi/10.1136/heartjnl-2017-312146
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http://dx.doi.org/10.1136/heartjnl-2017-312146DOI Listing
February 2019
1 Read

Mixed cerebrovascular disease in an elderly patient with mixed vascular risk factors: a case report.

BMC Neurol 2019 Feb 12;19(1):26. Epub 2019 Feb 12.

Department of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou Province, China.

Background: Mixed cerebrovascular disease is a diagnostic entity that presents with hemorrhagic and ischemic stroke clinically and/or subclinically. Here, we report a patient with mixed vascular risk factors, who presented with multiple intracerebral hemorrhages and a simultaneously occurring cerebral infarction with hemorrhagic transformation.

Case Presentation: A 63-year-old male with no history of trauma or prior neurological disease presented with a sudden onset of weakness in his right limbs, followed by an episode of focal seizure without impaired awareness. Read More

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http://dx.doi.org/10.1186/s12883-019-1248-zDOI Listing
February 2019

Roseomonas mucosa infective endocarditis in patient with systemic lupus erythematosus: case report and review of literature.

BMC Infect Dis 2019 Feb 12;19(1):140. Epub 2019 Feb 12.

Department of Laboratory Medicine, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, Guangdong, China.

Background: Roseomonas mucosa, as a Gram-negative coccobacilli, is an opportunistic pathogen that has rarely been reported in human infections. Here we describe a case of bacteremia in an infective endocarditis patient with systemic lupus erythematosus (SLE).

Case Presentations: A 44-year-old female patient with SLE suffered bacteremia caused by Roseomonas mucosa complicated with infective endocarditis (IE). Read More

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http://dx.doi.org/10.1186/s12879-019-3774-0DOI Listing
February 2019

Antimicrobial activity of dalbavancin tested against Gram-positive organisms isolated from patients with infective endocarditis in US and European medical centres.

J Antimicrob Chemother 2019 Feb 7. Epub 2019 Feb 7.

JMI Laboratories, North Liberty, IA, USA.

Background: The management of endocarditis requires aggressive and prolonged antimicrobial treatment. We evaluated the in vitro activity of dalbavancin against bacteria from patients with infective endocarditis.

Methods: A total of 626 Gram-positive organisms were collected from patients with a diagnosis of bacterial endocarditis in the USA (n = 222) and Europe (n = 404) from 2007 to 2017 via the SENTRY Antimicrobial Surveillance Program and were tested for susceptibility to dalbavancin and comparators by broth microdilution. Read More

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http://dx.doi.org/10.1093/jac/dkz006DOI Listing
February 2019
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Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus bacteremia - Nationwide Estimates of 30-day Readmission, In-hospital Mortality, Length of Stay, and Cost in the US.

Clin Infect Dis 2019 Feb 11. Epub 2019 Feb 11.

Department of Pediatrics, University of Mississippi Medical Center, Jackson, Mississippi.

Background: Information on outcomes of methicillin-susceptible and -resistant S. aureus (MSSA and MRSA, respectively) bacteremia, particularly readmission is scarce, and require further research to inform optimal patient care.

Methods: We performed a retrospective analysis using the 2014 Nationwide Readmissions Database, capturing 49. Read More

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http://dx.doi.org/10.1093/cid/ciz123DOI Listing
February 2019
1 Read

Endomyocardial fibrosis presenting as apical calcification and infective endocarditis.

Eur Heart J 2019 Feb 7. Epub 2019 Feb 7.

Department of Cardiovascular Medicine, Hokkaido University Hospital, Kita-14, Nishi-5, Kita-ku, Sapporo, Japan.

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http://dx.doi.org/10.1093/eurheartj/ehz051DOI Listing
February 2019
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Corrigendum to: Incidence of infective endocarditis in patients considered at moderate risk.

Authors:

Eur Heart J 2019 Feb 6. Epub 2019 Feb 6.

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http://dx.doi.org/10.1093/eurheartj/ehz019DOI Listing
February 2019
1 Read

Tricuspid valve relocation with endomyocardial fibrosis removal for Löeffler's endocarditis.

Eur J Cardiothorac Surg 2019 Feb 8. Epub 2019 Feb 8.

Division of Cardiovascular Surgery, Department of Surgery, Shiga University of Medical Science, Otsu, Japan.

Löffler endocarditis with hypereosinophilic syndrome is rare but can cause critical ventricular obliteration by endomyocardial fibrosis. A 52-year-old woman experienced severe right heart failure with extreme shrinkage of her right ventricle, severe tricuspid regurgitation and marked right atrial enlargement. Preoperative tests showed identical pressures in the right atrium and pulmonary artery. Read More

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http://dx.doi.org/10.1093/ejcts/ezy487DOI Listing
February 2019
1 Read

Tricuspid Papillary Fibroelastoma at Multimodal Imaging.

J Cardiovasc Echogr 2018 Oct-Dec;28(4):236-238

Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.

Papillary fibroelastoma is a rare benign cardiac tumor, second after cardiac myxoma as more frequent cardiac valvular tumor. The therapy is usually based on surgery according to size, mobility, symptoms, and risks of surgery. We report the case of a 67-year old female with transient ischemic attack. Read More

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http://www.jcecho.org/text.asp?2018/28/4/236/248413
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http://dx.doi.org/10.4103/jcecho.jcecho_48_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341851PMC
February 2019
5 Reads

Mitral Prolapse: An Old Mysterious Entity - The Incremental Role of Multimodality Imaging in Sports Eligibility.

J Cardiovasc Echogr 2018 Oct-Dec;28(4):207-217

Luigi Vanvitelli University, Monaldi Hospital, AORN Ospedali Dei Colli, Naples, Italy.

Mitral valve prolapse is generally a benign condition characterized by fibromyxomatous changes of the mitral leaflet with displacement into the left atrium and late-systolic regurgitation. Although it is an old clinical entity, it still arouses perplexity in diagnosis and clinical management. Complications, such as mitral regurgitation (MR), atrial fibrillation, congestive heart failure, endocarditis, ventricular arrhythmias, and sudden cardiac death (SCD), have been reported. Read More

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http://dx.doi.org/10.4103/jcecho.jcecho_42_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341849PMC
February 2019
1 Read

Methicillin-Resistant Staphylococcus aureus Endocarditis from a Diabetic Foot Ulcer .

J Am Podiatr Med Assoc 2018 Nov;108(6):528-531

Diabetic foot infections are a common cause of morbidity and mortality in the United States, and successful treatment often requires an aggressive and prolonged approach. Recent work has elucidated the importance of appropriate therapy for a given severity of diabetic foot infection, and highlighted the ongoing risk such patients have for subsequent invasive life-threatening infection should diabetic foot ulcers fail to heal. The authors describe the case of a man with diabetes who had prolonged, delayed healing of a diabetic foot ulcer. Read More

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http://www.japmaonline.org/doi/10.7547/17-139
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http://dx.doi.org/10.7547/17-139DOI Listing
November 2018
2 Reads

Improving medical care and prevention in adults with congenital heart disease-reflections on a global problem-part II: infective endocarditis, pulmonary hypertension, pulmonary arterial hypertension and aortopathy.

Cardiovasc Diagn Ther 2018 Dec;8(6):716-724

Department of Pediatric Cardiology and Congenital Heart Disease, German Heart Center Munich, Technical University Munich, Munich, Germany.

Despite relevant residua and sequels, follow-up care of adults with congenital heart disease (ACHD) is too often not performed by/in specialized and/or certified physicians or centers although major problems in the long-term course may develop. The most relevant encompass heart failure, cardiac arrhythmias, heart valve disorders, pulmonary vascular disease, infective endocarditis (IE), aortopathy and non-cardiac comorbidities. The present publication emphasizes current data on IE, pulmonary and pulmonary arterial hypertension and aortopathy in ACHD and underlines the deep need of an experienced follow-up care by specialized and/or certified physicians or centers, as treatment regimens from acquired heart disease can not be necessarily transmitted to CHD. Read More

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http://dx.doi.org/10.21037/cdt.2018.10.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331381PMC
December 2018
1 Read

Improving medical care and prevention in adults with congenital heart disease-reflections on a global problem-part I: development of congenital cardiology, epidemiology, clinical aspects, heart failure, cardiac arrhythmia.

Cardiovasc Diagn Ther 2018 Dec;8(6):705-715

Department of Pediatric Cardiology and Congenital Heart Disease, German Heart Center Munich, Technical University Munich, Munich, Germany.

Today most patients with congenital heart defects (CHD) survive into adulthood. Unfortunately, despite relevant residua and sequels, follow-up care of adults with congenital heart disease (ACHD) is not performed in specialized and/or certified physicians or centres. Major problems in the long-term course encompass heart failure, cardiac arrhythmias, heart valve disorders, pulmonary vascular disease, infective endocarditis, aortopathy and non-cardiac comorbidities. Read More

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http://dx.doi.org/10.21037/cdt.2018.10.15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331379PMC
December 2018
1 Read

Methicillin-resistant Staphylococcus aureus: an overview of basic and clinical research.

Nat Rev Microbiol 2019 Feb 8. Epub 2019 Feb 8.

Duke University Medical Center, Durham, NC, USA.

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most successful modern pathogens. The same organism that lives as a commensal and is transmitted in both health-care and community settings is also a leading cause of bacteraemia, endocarditis, skin and soft tissue infections, bone and joint infections and hospital-acquired infections. Genetically diverse, the epidemiology of MRSA is primarily characterized by the serial emergence of epidemic strains. Read More

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http://dx.doi.org/10.1038/s41579-018-0147-4DOI Listing
February 2019
1 Read

Endocarditis following IUD insertion in a patient with tetralogy of Fallot.

BMJ Case Rep 2019 Feb 7;12(2). Epub 2019 Feb 7.

Department of Medicine, University of Washington, Seattle, Washington, USA.

The role of antibiotic prophylaxis for prevention of infective endocarditis is unknown. Endocarditis prophylaxis is recommended for certain high-risk individuals prior to dental procedures. To our knowledge, this is the first case reported in the literature of a patient with complex congenital heart disease developing endocarditis in the period immediately following otherwise uncomplicated intrauterine device insertion. Read More

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http://dx.doi.org/10.1136/bcr-2018-227962DOI Listing
February 2019
1 Read

A new simplified predictive model for mortality in methicillin-resistant Staphylococcus aureus bacteremia.

Eur J Clin Microbiol Infect Dis 2019 Feb 8. Epub 2019 Feb 8.

Anti-Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, 259 Mack Ave, Detroit, MI, 48201, USA.

Adjustment for confounding is important in observational methicillin-resistant Staphylococcus aureus bacteremia (MRSAB) studies due to the wide spectrum of disease severity and baseline health status that patients present with. The objectives of this study were to develop a simplified MRSAB-specific scoring model to estimate the risk of 30-day all-cause mortality and to compare its performance to the APACHE II and Pitt Bacteremia scores. Retrospective, singe-center, cohort study in adults with MRSAB 2008 to 2018. Read More

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http://dx.doi.org/10.1007/s10096-018-03464-0DOI Listing
February 2019
1 Read

Cardiovascular Manifestations of Inflammatory Bowel Disease: Pathogenesis, Diagnosis, and Preventive Strategies.

Gastroenterol Res Pract 2019 13;2019:3012509. Epub 2019 Jan 13.

Department of Internal Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi 700111, Romania.

Inflammatory bowel disease (IBD) refers to a group of chronic inflammatory diseases that targets mainly the gastrointestinal tract. The clinical presentation of IBD includes both gastrointestinal manifestations and extraintestinal manifestations (EIM). The reported cardiovascular manifestations in IBD patients include pericarditis, myocarditis, venous and arterial thromboembolism, arrhythmias, atrioventricular block, heart failure, endocarditis, valvulopathies, and Takayasu arteritis. Read More

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https://www.hindawi.com/journals/grp/2019/3012509/
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http://dx.doi.org/10.1155/2019/3012509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348818PMC
January 2019
3 Reads

Mycotic Aneurysm of the Ulnar Artery Secondary to Bacillus Calmette-Guérin Therapy for Bladder Cancer: A Rare Presentation of Hypothenar Hammer Syndrome.

J Hand Surg Am 2019 Feb 4. Epub 2019 Feb 4.

Department of Orthopedic Surgery, Mayo Clinic, Jacksonville, FL. Electronic address:

Mycotic aneurysms, especially those of the upper extremity, are rarely reported in literature. These aneurysms are caused by bacterial endocarditis and, therefore, are more commonly seen in patients who are in an immunocompromised state, including those requiring bacillus Calmette-Guérin (BCG) therapy for bladder cancer. Owing to the inevitable rupture of mycotic aneurysms, the standard treatment is surgical repair with appropriate secondary antibiotics. Read More

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http://dx.doi.org/10.1016/j.jhsa.2018.12.001DOI Listing
February 2019
1 Read

Subclinical thrombus formation in bioprosthetic pulmonary valve conduits.

Int J Cardiol 2019 Jan 30. Epub 2019 Jan 30.

Pediatric Cardiology and Intensive Care, University Medical Center Göttingen, Germany. Electronic address:

Objectives: Bioprosthetic pulmonary valve conduits have been reported with an increased risk of endocarditis. Thrombus formation is considered as source of these serious and life-threatening infections. We reviewed a series of explanted valved pulmonary conduits for histological evidence for thrombus formation. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.01.095DOI Listing
January 2019
1 Read

Infective Endocarditis in Injection Drug Users: A Recurrent Disease.

J Am Coll Cardiol 2019 Feb;73(5):571-572

Aix-Marseille Université, Institut de Recherche pour le Developpement, Assistance Publique Hopitaux de Marseille, Microbes Evolution Phylogeny and Infection, Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France.

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http://dx.doi.org/10.1016/j.jacc.2018.10.081DOI Listing
February 2019
1 Read

Clinical Outcomes of Infective Endocarditis in Injection Drug Users.

J Am Coll Cardiol 2019 Feb;73(5):559-570

Cardiovascular Outcomes Research Laboratories, Division of Cardiac Surgery, David Geffen School of Medicine, University of California, Los Angeles, California. Electronic address:

Background: Rising rates of hospitalization for infective endocarditis (IE) have been increasingly tied to rising injection drug use (IDU) associated with the opioid epidemic.

Objectives: This study analyzed recent trends in IDU-IE hospitalization and characterized outcomes and readmissions for IDU-IE patients.

Methods: The authors evaluated the National Readmissions Database (NRD) for IE cases between January 2010 and September 2015. Read More

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http://dx.doi.org/10.1016/j.jacc.2018.10.082DOI Listing
February 2019
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Durability of Transcatheter and Surgical Bioprosthetic Aortic Valves in Patients at Lower Surgical Risk.

J Am Coll Cardiol 2019 Feb;73(5):546-553

Department of Cardiothoracic Surgery, The Heart Centre, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

Background: Transcatheter aortic valve replacement (TAVR) is an alternative to surgical aortic valve replacement (SAVR) in patients with severe aortic stenosis and intermediate or high surgical risk.

Objectives: The aim of this study was to compare the durability of transcatheter and surgical bioprosthetic aortic valves using standardized criteria.

Methods: In the NOTION (Nordic Aortic Valve Intervention) trial, all-comer patients with severe aortic stenosis and lower surgical risk for mortality were randomized 1:1 to TAVR (n = 139) or SAVR (n = 135). Read More

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http://dx.doi.org/10.1016/j.jacc.2018.10.083DOI Listing
February 2019
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Neutrophil Extracellular Traps Enhance Staphylococcus Aureus Vegetation Formation through Interaction with Platelets in Infective Endocarditis.

Thromb Haemost 2019 Feb 7. Epub 2019 Feb 7.

Department of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.

The mechanisms or host factors involved in septic thrombus or vegetation formation in -induced infective endocarditis (IE) are unclear. Using an experimental endocarditis rat model, here we demonstrated that HG001-induced vegetation was composed of bacterial floes encased in aggregated platelets and surrounded by neutrophil extracellular traps (NETs). In vitro data demonstrated that platelets contribute to both biofilm and NET formation. Read More

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http://dx.doi.org/10.1055/s-0039-1678665DOI Listing
February 2019
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Knowledge of antibiotics and antimicrobial resistance among final year dental students of Polish medical schools - a cross-sectional study.

Eur J Dent Educ 2019 Feb 6. Epub 2019 Feb 6.

Department of Epidemiology and Clinical Microbiology, National Medicines Institute, Chelmska 30/34, 00-725, Warsaw, Poland.

Introduction: Antimicrobial resistance has been one of the biggest global concerns. Dentists constitute an important group of antibiotic prescribers and it was shown that their therapeutic decisions are not always rational. In this paper we present knowledge of antibiotics prescription rules and antimicrobial resistance among graduating dentistry students from all dentistry faculties of medical universities in Poland, who will soon join the group of antibiotics prescribers. Read More

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http://dx.doi.org/10.1111/eje.12430DOI Listing
February 2019
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1.448 Impact Factor

An Inhibitory Effect of Dryocrassin ABBA on vWbp That Protects Mice From Pneumonia.

Front Microbiol 2019 23;10. Epub 2019 Jan 23.

College of Animal Sciences, Jilin University, Changchun, China.

Von Willebrand factor-binding protein (vWbp), secreted by (), can activate host prothrombin, convert fibrinogen to fibrin clots, induce blood clotting, and contribute to pathophysiology of -related diseases, including infective endocarditis, staphylococcal sepsis and pneumonia. Therefore, vWbp is an promising drug target in the treatment of related infections. Here, we report that dryocrassin ABBA (ABBA), a natural compound derived from , can significantly inhibit the coagulase activity of vWbp by directly interacting with vWbp without killing the bacteria or inhibiting the expression of the vWbp. Read More

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https://www.frontiersin.org/article/10.3389/fmicb.2019.00007
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http://dx.doi.org/10.3389/fmicb.2019.00007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351477PMC
January 2019
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[Pediatric clinical experience in infectious endocarditis due to Candida spp].

Rev Chilena Infectol 2018 ;35(5):553-559

Departamento de Infectología Pediátrica, Hospital Civil de Guadalajara "Fray Antonio Alcalde", México.

Background: Treatment and outcome of Candida spp infectious endocarditis in children it most be based on treatment guidelines, however there are some controversies.

Aim: To describe our experience on treatment of pediatric candidal infective endocarditis.

Methods: Analytic prospective study, from January 2006 to December 2017. Read More

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http://dx.doi.org/10.4067/s0716-10182018000500553DOI Listing
January 2018
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Incidence of infective endocarditis before and after the guideline modification regarding a more restrictive use of prophylactic antibiotics therapy in the United States of America and Europe.

Minerva Cardioangiol 2019 Feb 5. Epub 2019 Feb 5.

Center of Cardiology, Cardiology I, University Medical Center Mainz, Johannes Gutenberg-University Mainz, Mainz, Germany.

Infective endocarditis (IE) is a potentially life-threatening disease. Regardless the improvements in IE management, it remains associated with high mortality and severe complications. Staphylococci and streptococci account for 80% of all IE cases. Read More

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http://dx.doi.org/10.23736/S0026-4725.19.04870-9DOI Listing
February 2019
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Similarities and differences in antimicrobial prescribing between major city hospitals and regional and remote hospitals in Australia.

Int J Antimicrob Agents 2019 Feb 26;53(2):171-176. Epub 2018 Oct 26.

National Centre for Antimicrobial Stewardship, Peter Doherty Research Institute for Infection and Immunity, Melbourne, VIC, Australia; University of Melbourne, Faculty of Medicine, Dentistry and Health Sciences, Department of Medicine - Royal Melbourne Hospital, Melbourne, VIC, Australia; Victorian Infectious Diseases Service, Royal Melbourne Hospital, Melbourne, VIC, Australia.

Many regional and remote hospitals (RRHs) do not have the specialist services that usually support antimicrobial stewardship (AMS) programmes in major city hospitals. It is not known if this is associated with higher rates of inappropriate antimicrobial prescribing. The aim of this study was to identify similarities and differences in antimicrobial prescribing patterns between major city hospitals and RRHs in Australia. Read More

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http://dx.doi.org/10.1016/j.ijantimicag.2018.10.009DOI Listing
February 2019
2 Reads