28,646 results match your criteria Endemic Syphilis


Sexually Acquired Syphilis. Part 2: Laboratory diagnosis, management, and prevention.

J Am Acad Dermatol 2019 Apr 12. Epub 2019 Apr 12.

Department of Dermatology, Kaiser Permanente, San Francisco, CA.

Methods: for laboratory diagnosis of syphilis include direct detection of T. pallidum subsp. pallidum and serologic testing. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaad.2019.02.074DOI Listing

[The ocular manifestations of human immunodeficiency virus and syphilis coinfection].

Zhonghua Yan Ke Za Zhi 2019 Apr;55(4):267-272

Department of Ophthalmology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.

To investigate the ocular manifestations of human immunodeficiency virus (HIV) and syphilis coinfection. A retrospective analysis of the ocular manifestations was carried out in 27 patients (54 eyes) diagnosed as syphilis and HIV coinfection by the Department of Infectious Medicine in Peking Union Medical College Hospital during the years of 2006-2017. The research included 26 males and 1 female, aging from 24 to 76 years old, with a mean age of 40. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2019.04.008DOI Listing
April 2019
1 Read

Detection of specific Treponema species and Dichelobacter nodosus from digital dermatitis (Mortellaro's disease) lesions in Swiss cattle.

Schweiz Arch Tierheilkd 2019 Apr;161(4):207-215

Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern.

Introduction: The aim of this study was to determine the prevalence of the three Treponema species as well as D. nodosus in Digital dermatitis (DD) and slurry of Swiss cattle using PCR. A total of 86 specimens from 24 farms were enrolled in the study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17236/sat00201DOI Listing
April 2019
2 Reads

Sexually Transmitted Diseases in the Emergency Department.

Emerg Med Clin North Am 2019 May;37(2):165-192

Prisma Health, University of South Carolina School of Medicine Greenville, 701 Grove Road, Greenville, SC 29605, USA. Electronic address:

Sexually transmitted diseases (STDs) continue to be underrecognized leading to devastating health and economic consequences. Emergency clinicians play an important role in diagnosing and managing STDs and in improving health care outcomes for both the patient and their partners. In addition, antibiotic resistance and emerging infections continue to challenge providers in clinical practice. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.emc.2019.01.001DOI Listing
May 2019
1 Read

Diagnosis of congenital/perinatal infections by neonatologists: a national survey.

J Perinatol 2019 Mar 26. Epub 2019 Mar 26.

Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA.

Objective: To describe the clinical approach used by neonatologists for diagnosis of congenital/perinatal infections (CPI); no such data currently exist.

Study Design: A national survey regarding the diagnosis of toxoplasma, syphilis, rubella, cytomegalovirus, and herpes simplex virus (HSV) infection in neonates.

Result: We received 553 (11%) responses. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41372-019-0364-3DOI Listing
March 2019
1 Read

Analysis of EEG Lemple-Ziv complexity and correlative aspects before and after treatment of anti-syphilis therapy for neurosyphilis.

Neurol Res 2019 Mar;41(3):199-203

a Department of Neurology , Beijing Ditan Hospital, Capital Medical University , Beijing , China.

Objective To investigate the diagnostic value of electroencephalogram (EEG) complexity in patients with neurosyphilis by comparing the changes of electroencephalogram Lempel-Ziv complexity (EEG-LZC) before and after anti-syphilis treatment. Methods The EEG complexity of neurosyphilis patients diagnosed in our hospital from July in 2015 to June in 2017 was analyzed and compared with other diagnostic results such as serology examination and cerebrospinal fluid examination. Results A total of 27 patients were diagnosed, including 19 males and 8 females, of which 6 were mesenchymal(cerebrospinal membrane and meningeal vascular), 16 were parenchymal(paralytic dementia, spinal cord tuberculosis and optic neuropathy), and 5 were asymptomatic. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01616412.2018.1520438DOI Listing
March 2019
1 Read

A Rare Case of HIV-Induced Inflammatory Demyelinating Polyneuropathy.

Am J Med Case Rep 2019 21;7(1):5-8. Epub 2019 Jan 21.

Department of Medicine, SUNY Downstate Medical Center, 450 Clarkson Avenue Brooklyn, NY 11203 (718) 270-2030.

Background: Acute inflammatory demyelinating polyneuropathy (AIDP) is an uncommon form of neuropathy in HIV-infected patients that can cause pain, sensory disturbance, and motor weakness.

Case Presentation: A 23-year-old African American male with past medical history of Guillain-Barre Syndrome (GBS), Lyme disease, and sexually transmitted infections including syphilis and chlamydia presented with acute back pain radiating to bilateral lower extremities with worsening right foot weakness for four days. Cerebrospinal fluid (CSF) studies including meningoencephalitis panel were negative as well as blood tests for Lyme disease and HIV antibody testing. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12691/ajmcr-7-1-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424340PMC
January 2019
6 Reads

Syphilis in female sex workers: an epidemiological study of the highway system of the state of Pará, northern Brazil.

Rev Soc Bras Med Trop 2019 Mar 18;52:e20180064. Epub 2019 Mar 18.

Grupo de Estudo e Pesquisa em Populações Vulneráveis, Instituto de Estudos Costeiros, Universidade Federal do Pará, Bragança, PA, Brasil.

Introduction: Female sex workers (FSWs) are considered a bridge for transmission of pathogens from high-risk to general populations. We assessed the epidemiological status of syphilis in FSWs along the Pará highway system.

Methods: Two hundred and twenty-two FSWs were interviewed and samples were analyzed using rapid qualitative tests and real-time polymerase chain reaction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/0037-8682-0064-2018DOI Listing

Risk Factors for Congenital Syphilis Transmitted from Mother to Infant - Suzhou, China, 2011-2014.

MMWR Morb Mortal Wkly Rep 2019 Mar 15;68(10):247-250. Epub 2019 Mar 15.

Mother-to-child transmission of syphilis remains a major global public health issue, and elimination of congenital syphilis is one of the millennium development goals of the World Health Organization (1). In 2012, an estimated 930,000 maternal syphilis infections caused 350,000 adverse pregnancy outcomes, including 143,000 early fetal deaths and stillbirths, 62,000 neonatal deaths, 44,000 preterm or low-weight births, and 102,000 infected infants worldwide (2). In China, the number of congenital syphilis cases reported annually increased from 468 in 2000 to 10,032 in 2013; the corresponding national congenital syphilis incidence rate increased nearly 26-fold, from 2. Read More

View Article

Download full-text PDF

Source
http://www.cdc.gov/mmwr/volumes/68/wr/mm6810a4.htm?s_cid=mm6
Publisher Site
http://dx.doi.org/10.15585/mmwr.mm6810a4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421965PMC
March 2019
12 Reads

Transfusion Transmissible Infections: Maximizing Donor Surveillance.

Cureus 2018 Dec 28;10(12):e3787. Epub 2018 Dec 28.

Immunology, Shifa International Hospital, Islamabad, PAK.

Introduction The World Health Organization (WHO) recommends that all blood transfusion services must screen donated blood for human immunodeficiency virus (HIV) one and two, hepatitis B, hepatitis C and syphilis. A mandatory screening for malaria is also warranted in malaria endemic areas. Our study aimed at analyzing the prevalence and different diagnostic methods of screening transfusion transmitted infections (TTIs) in replacement and voluntary, non-remunerated donors in the blood bank of a tertiary care hospital in Islamabad, Pakistan. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7759/cureus.3787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402742PMC
December 2018
1 Read

Case 8-2019: A 58-Year-Old Woman with Vision Loss, Headaches, and Oral Ulcers.

N Engl J Med 2019 Mar;380(11):1062-1071

From the Departments of Ophthalmology, Medicine, and Cell Biology, Oregon Health and Science University, and Legacy Devers Eye Institute - both in Portland (J.T.R.); and the Department of Ophthalmology, Ophthalmic Consultants of Boston (L.M.R.), the Departments of Radiology (K.A.B.), Medicine (M.B.B.), and Pathology (M.P.H.), Massachusetts General Hospital, and the Departments of Radiology (K.A.B.), Medicine (M.B.B.), and Pathology (M.P.H.), Harvard Medical School - all in Boston.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMcpc1810395DOI Listing
March 2019
2 Reads

Conducting a secondary data analysis to estimate the incidence of congenital syphilis in South Africa, 2010 - 2016.

Pan Afr Med J 2018 18;30(Suppl 1):16. Epub 2018 May 18.

Rollins School of Public Health, Emory University, Atlanta, USA.

Analysis of existing health data is often used as a cost-effective and time-efficient means to provide evidence to inform important public health decisions. However, the accuracy of the resultant decisions largely depends on the quality of the accessible data, and how the data are processed, analyzed, interpreted and reported. This case study, based on an actual secondary data analysis that was conducted by a trainee of the South African Field Epidemiology Training Programme during April 2017, was designed to provide a classroom simulation of practical considerations that should be taken into account when planning an analysis of a secondary dataset. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.11604/pamj.supp.2018.30.1.15272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379546PMC
March 2019
1 Read

Syphilis and human immunodeficiency virus infections among pregnant women attending antenatal care clinic of Gondar family guidance association, Northwest Ethiopia: implication for prevention of mother to child transmission.

Reprod Health 2019 Mar 4;16(1):27. Epub 2019 Mar 4.

School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, P.O Box 196, Gondar, Ethiopia.

Background: Sexually transmitted infections constitute a major public health problem worldwide. Syphilis and HIV infections cause various adverse pregnancy outcomes. Therefore, the aim of this study was to determine the seroprevalence of HIV and syphilis infections among pregnant women at Gondar Family Guidance Association clinic, northwest Ethiopia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12978-019-0691-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399918PMC
March 2019
2 Reads

Reemerging diseases in Brazil: sociodemographic and epidemiological characteristics of syphilis and its under-reporting.

Rev Soc Bras Med Trop 2019 Feb 21;52:e20180226. Epub 2019 Feb 21.

Programa de Pós-graduação em Odontologia Preventiva e Social, Faculdade de Odontologia de Araçatuba, Universidade Estadual Paulista, Araçatuba, SP, Brasil.

Introduction: This paper analyzed sociodemographic and epidemiological data of individuals with syphilis as well as the compulsory reporting of the disease, for being a reemerging disease in Brazil.

Methods: General information and sociodemographic, epidemiological, clinical, and laboratory data were verified in compulsory reporting.

Results: From 2010 to 2016, 157 reporting forms were explored. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/0037-8682-0226-2018DOI Listing
February 2019
1 Read

Comparative Performance of the Reverse Algorithm Using Architect Syphilis TP Versus the Traditional Algorithm Using Rapid Plasma Reagin in Florida's Public Health Testing Population.

Ann Lab Med 2019 Jul;39(4):396-399

Bureau of Public Health Laboratories, Florida Department of Health, Jacksonville, FL, USA.

In Florida, where syphilis is a reportable disease, the number of primary and secondary (P&S) syphilis cases has increased from 3,266 in 2008-2010 to 5,340 in 2013-2015, a 63% increase. The objective of this study was to compare the performance and sensitivity of the syphilis reverse algorithm with the traditional algorithm for detecting P&S (infectious) syphilis cases. Clinical specimens from individuals who self-referred for syphilis testing at public health clinics were processed using the traditional algorithm (non-treponemal rapid plasma reagin (RPR) test followed by a confirmatory treponemal (EIA) test) and then further tested with the Architect Syphilis TP (ASTP) immunoassay (Abbott Diagnostics, Chicago, IL, USA) or by RPR confirmation, if needed (reverse algorithm). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3343/alm.2019.39.4.396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400719PMC
July 2019
2 Reads

Epidemiological situation of yaws in the Americas: A systematic review in the context of a regional elimination goal.

PLoS Negl Trop Dis 2019 02 25;13(2):e0007125. Epub 2019 Feb 25.

Independent consultant, Madrid, Spain.

Background: Yaws is targeted for eradication by 2020 in the WHA66.12 resolution of the World Health Assembly. The objective of this study was to describe the occurrence of yaws in the Americas and to contribute to the compilation of evidence based on published data to undertake the certification of yaws eradication. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pntd.0007125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405159PMC
February 2019
2 Reads

Mother-to-child transmission and gestational syphilis: Spatial-temporal epidemiology and demographics in a Brazilian region.

PLoS Negl Trop Dis 2019 02 21;13(2):e0007122. Epub 2019 Feb 21.

Faculdade de Ciências da Saúde, Biomedicina, Universidade do Oeste Paulista, Presidente Prudente, SP, Brazil.

Syphilis is a Sexually Transmitted Infection (IST) with significant importance to public health, due to its impact during pregnancy (Gestational Syphilis-GS); especially because syphilis can affect fetus and neonates' development (mother-to-child transmission-MTCT of syphilis), by increasing susceptibility to abortion, premature birth, skeletal malformations, meningitis and pneumonia. Measures to control and eliminate MTCT of syphilis have failed on the last few years in Brazil and this research aimed to identify the seasonality of notified cases of syphilis in a region of São Paulo state. The studied region, Pontal do Paranapanema, comprises 32 cities located in the West of São Paulo state, in Brazil. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pntd.0007122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383870PMC
February 2019
2 Reads

Profile of the tprK gene in primary syphilis patients based on next-generation sequencing.

PLoS Negl Trop Dis 2019 02 21;13(2):e0006855. Epub 2019 Feb 21.

Center of Clinical Laboratory, Zhongshan Hospital, School of Medicine, Xiamen University, Xiamen, China.

Background: The highly variable tprK gene of Treponema pallidum has been acknowledged to be one of the mechanisms that causes persistent infection. Previous studies have mainly focused on the heterogeneity in tprK in propagated strains using a clone-based Sanger approach. Few studies have investigated tprK directly from clinical samples using deep sequencing. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pntd.0006855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400401PMC
February 2019

Enigma of serpiginous choroiditis.

Indian J Ophthalmol 2019 Mar;67(3):325-333

Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Serpiginous choroiditis (SC) is an asymmetrically bilateral inflammation of the choroid that leads to loss of choriocapillaris atrophy or loss of overlying retinal pigment epithelium. Over the last few decades, SC has passed through a long evolution of nomenclature, etiologies and morphological variations. Initially diagnosed in patients with tuberculosis and syphilis, SC was predominantly considered as autoimmune process. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/ijo.IJO_822_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407399PMC
March 2019
1 Read

Antibiotic treatment for newborns with congenital syphilis.

Cochrane Database Syst Rev 2019 02 15;2:CD012071. Epub 2019 Feb 15.

C/o Cochrane Pregnancy and Childbirth Group, Department of Women's and Children's Health, The University of Liverpool, First Floor, Liverpool Women's NHS Foundation Trust, Crown Street, Liverpool, UK, L8 7SS.

Background: Congenital syphilis continues to be a substantial public health problem in many parts of the world. Since the first use of penicillin for the treatment of syphilis in 1943, which was a notable early success, it has remained the preferred and standard treatment including for congenital syphilis. However, the treatment of congenital syphilis is largely based on clinical experience and there is extremely limited evidence on the optimal dose or duration of administration of penicillin or the use of other antibiotics. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/14651858.CD012071.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378924PMC
February 2019
2 Reads

Multimodal Imaging of Atypical Acute Syphilitic Posterior Placoid Chorioretinitis Mimicking a White Dot Syndrome.

Ophthalmic Surg Lasers Imaging Retina 2019 02;50(2):e52-e55

As rates of infectious syphilis continue to rise in the U.S., it is important to be familiar with known manifestations of ocular syphilis as well as report presentations not previously described in the literature. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3928/23258160-20190129-20DOI Listing
February 2019

Increased Methamphetamine, Injection Drug, and Heroin Use Among Women and Heterosexual Men with Primary and Secondary Syphilis - United States, 2013-2017.

MMWR Morb Mortal Wkly Rep 2019 Feb 15;68(6):144-148. Epub 2019 Feb 15.

Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, CDC.

During 2013-2017, the national annual rate of reported primary and secondary (P&S) syphilis cases in the United States increased 72.7%, from 5.5 to 9. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15585/mmwr.mm6806a4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375651PMC
February 2019
2 Reads

Persistent high-risk behavior and escalating HIV, syphilis and hepatitis B incidences among men who have sex with men living in Bangui, Central African Republic.

Pan Afr Med J 2018 23;29:132. Epub 2018 Feb 23.

Laboratoire de Virologie, Hôpital Européen Georges Pompidou and Université Paris Descartes, Bio Sorbonne Paris Cité, Paris, France.

Introduction: HIV in sub-Saharan Africa remains a great concern in men who have sex with men (MSM). Intervention on MSM is a key strategy to control the burden of HIV among this population. Herein we assessed the effect of 2 years of HIV testing and counseling on risk-tacking and HIV and STI incidences among MSM living in Bangui in the Central African Republic. Read More

View Article

Download full-text PDF

Source
http://www.panafrican-med-journal.com/content/article/29/132
Publisher Site
http://dx.doi.org/10.11604/pamj.2018.29.132.12794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358028PMC
February 2019
11 Reads

Decline in the seroprevalence of syphilis markers among first-time blood donors in Libreville (Gabon) between 2004 and 2016.

BMC Public Health 2019 Feb 8;19(1):167. Epub 2019 Feb 8.

University of Cambridge, Cambridge, UK.

Background: Very few studies have been conducted on the seroprevalence of syphilis in Gabon. According to the World Health Organization, the average seroprevalence of syphilis has declined from 5.5 to 1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12889-019-6489-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368695PMC
February 2019
5 Reads
2.264 Impact Factor

Increasing Syphilis in Rhode Island: Return of an Old Foe.

R I Med J (2013) 2019 Feb 1;102(1):50-54. Epub 2019 Feb 1.

Associate Professor, Department of Medicine, Brown University, Providence, RI.

The number of people diagnosed with syphilis has increased significantly in the United States over the last decade. In Rhode Island, the number of new diagnoses has increased more than four-fold since 2008. Syphilis disproportionately impacts gay, bisexual, and other men who have sex with men (MSM), with those from African American and Hispanic/Latino communities most affected. Read More

View Article

Download full-text PDF

Source
February 2019
11 Reads

[Sexually Transmitted Infections - What's New, What's Different?]

Dtsch Med Wochenschr 2019 02 31;144(3):165-170. Epub 2019 Jan 31.

Abteilung Infektiologie, Klinik für Innere Medizin II, Universitätsklinikum Freiburg.

The incidence of sexually transmitted infections like syphilis or gonorrhea is still rising, particularly in the high-risk population of men having sex with men (MSM). Neisseria gonorrhoeae is capable to develop resistance to all antibiotics previously or currently used for treatment. Dual antimicrobial therapy with ceftriaxone and azithromycin is considered the current empirical first-line therapy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/a-0655-6657DOI Listing
February 2019
9 Reads

Integrated point-of-care testing (POCT) for HIV, syphilis, malaria and anaemia at antenatal facilities in western Kenya: a qualitative study exploring end-users' perspectives of appropriateness, acceptability and feasibility.

BMC Health Serv Res 2019 Jan 28;19(1):74. Epub 2019 Jan 28.

Liverpool School of Tropical Medicine, Liverpool, UK.

Background: HIV, syphilis, malaria and anaemia are leading preventable causes of adverse pregnancy outcomes in sub-Saharan Africa yet testing coverage for conditions other than HIV is low. Availing point-of-care tests (POCTs) at rural antenatal health facilities (dispensaries) has the potential to improve access and timely treatment. Fundamental to the adoption of and adherence to new diagnostic approaches are healthcare workers' and pregnant women's (end-users) buy-in. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12913-018-3844-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348645PMC
January 2019
1 Read

Management of sexual partners of pregnant women with syphilis in northeastern Brazil - a qualitative study.

BMC Health Serv Res 2019 Jan 24;19(1):65. Epub 2019 Jan 24.

Fortaleza Health Secretariat, Rua do Rosário, 263, Centro, Fortaleza, Ceará, CEP: 60.055-090, Brazil.

Background: Although there are public policies for eradicating congenital syphilis, they do not seem to be a routine in most health services. The objective of this study was to evaluate the management of sexual partners of pregnant women with syphilis in primary health care in northeastern Brazil.

Methods: This is a qualitative assessment carried out from February to October 2014 in the city of Fortaleza, Ceará, northeastern region of Brazil, through the observation of six primary health care centers and interviews with 21 professionals, six coordinators, nine women diagnosed with syphilis during antenatal care and four sexual partners. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12913-019-3910-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344990PMC
January 2019

Gummatous Syphilis Mimicking Malignant Bone Tumor on FDG PET/CT.

Clin Nucl Med 2019 Apr;44(4):313-316

From the PET Center, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China.

A 47-year-old woman suffered worsening pain in the waist and numbness in the right thigh for 1 month. MRI was performed to determine the cause, which detected an osteolytic lesion in the T12 vertebral body, suggestive of possible bone metastasis. FDG PET/CT scan was undertaken to detect the primary tumor, which only showed the same isolated lesion in the T12 without any other abnormal hypermetabolic lesion. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/RLU.0000000000002450DOI Listing
April 2019
6 Reads

Facial and genital lesions in baboons (Papio anubis) of Kibale National Park, Uganda.

Primates 2019 Mar 21;60(2):109-112. Epub 2019 Jan 21.

University Medical Center, University of Leipzig, Philipp-Rosenthal-Str. 27, 04103, Leipzig, Germany.

We describe and document with digital images two adult male baboons (Papio anubis) from the Kibale National Park, Uganda who were infected with some kind of disease having clinical signs suggestive of Treponema pallidum. One of these males was missing his premaxilla, part of the maxilla, upper incisors, canines, and possibly the first premolars. The condition of his scrotum was not seen. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10329-019-00715-2DOI Listing
March 2019
1 Read

Epidemiology survey of infectious diseases in North Korean travelers, 2015-2017.

BMC Infect Dis 2019 Jan 5;19(1):13. Epub 2019 Jan 5.

Department of Infectious Diseases, Bethune International Peace Hospital, NO.398, Zhongshanxi Road, Shijiazhuang, Hebei Prov, 050082, People's Republic of China.

Background: Up until now, there are limited studies available on the epidemiology of infectious diseases in Democratic People's Republic of Korea (DPRK, North Korea). However, different types of infectious diseases have been found in North Korean travelers at Dandong port. Entry surveillance data of those North Korean travelers may provide some insight into the probable epidemiology of some infectious diseases in DPRK. Read More

View Article

Download full-text PDF

Source
https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
Publisher Site
http://dx.doi.org/10.1186/s12879-018-3664-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321685PMC
January 2019
3 Reads

Prevalence and Trends of Major Transfusion Transmissible Infections among Blood Donors in Dire Dawa Blood bank, Eastern Ethiopia: Retrospective Study.

Ethiop J Health Sci 2018 Nov;28(6):701-710

Department of Medical Laboratory Sciences, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.

Background: Acquisition of transfusion transmissible infections in the process of therapeutic blood transfusion is a major global health challenge in transfusion medicine. This study aimed to determine the prevalence and trends of major transfusion transmissible infections among blood donors.

Method: A retrospective analysis of consecutive blood donors' records covering the period between July 2010 and June 2013 was conducted at Dire Dawa Blood Bank, Eastern Ethiopia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4314/ejhs.v28i6.4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308748PMC
November 2018
6 Reads

Laboratory evaluation of four HIV/syphilis rapid diagnostic tests.

BMC Infect Dis 2019 Jan 3;19(1). Epub 2019 Jan 3.

HIV/STI Reference Laboratory, Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.

Background: Sexually transmitted infections, such as HIV and syphilis, are one of the major health care problems worldwide, especially in low- and middle income countries. HIV screening programmes have been widely used for many years. The introduction of rapid point-of-care tests (RDTs) that can detect both HIV and syphilis, using one single blood specimen, would be a promising tool to integrate the detection of syphilis into HIV programmes and so improve the accessibility of syphilis testing and treatment. Read More

View Article

Download full-text PDF

Source
https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
Publisher Site
http://dx.doi.org/10.1186/s12879-018-3567-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318958PMC
January 2019
10 Reads

Topical treatment with gallium maltolate reduces Treponema pallidum subsp. pertenue burden in primary experimental lesions in a rabbit model of yaws.

PLoS Negl Trop Dis 2019 01 2;13(1):e0007076. Epub 2019 Jan 2.

Innovation to End Neglected Diseases (IT-ENDs), East Palo Alto, CA, United States of America.

Background: Gallium is a semi-metallic element known since the 1930s to have antimicrobial activity. This activity stems primarily from gallium's ability to mimic trivalent iron and disrupt specific Fe(III)-dependent pathways, particularly DNA synthesis (due to inhibition of ribonucleotide reductase). Because of its novel mechanism of action, gallium is currently being investigated as a new antibacterial agent, particularly in light of the increasing resistance of many pathogenic bacteria to existing antibiotics. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pntd.0007076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331133PMC
January 2019
2 Reads

Generalized Convulsive Status Epilepticus Secondary to Jarisch-Herxheimer Reaction in Neurosyphilis: A Case Report and Literature Review.

Neurologist 2019 Jan;24(1):29-32

Department of Neurology, Health Sciences Center, Federal University of Santa Maria, Rio Grande do Sul, Brazil.

Introduction: Jarisch-Herxheimer reaction (JHR) is defined as a transient immunologic reaction, classically seen in patients during syphilis treatment. JHR is a rare cause of status epilepticus (SE) in neurosyphilis. We describe a case of generalized convulsive SE (GCSE) probably secondary to JHR in a patient with neurosyphilis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/NRL.0000000000000219DOI Listing
January 2019
5 Reads

Dual screen and confirm rapid test does not reduce overtreatment of syphilis in pregnant women living in a non-venereal treponematoses endemic region: a field evaluation among antenatal care attendees in Burkina Faso.

Sex Transm Infect 2018 Dec 22. Epub 2018 Dec 22.

Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.

Objectives: In resource-limited settings, screening pregnant women for syphilis using rapid diagnostic tests (RDTs) is a key tool in the prevention of congenital syphilis. However, most syphilis RDTs detect only treponemal antibodies (T-RDT), meaning antibiotics may be provided unnecessarily to previously treated pregnant women, particularly in non-venereal treponematoses endemic regions. We estimated the potential reduction in overtreatment when comparing T-RDT (SD Bioline) to a newer rapid test (Dual Path Platform (DPP) Screen and Confirm Assay, Chembio) detecting both treponemal and non-treponemal antibodies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/sextrans-2018-053722DOI Listing
December 2018

Optic neuritis caused by the re-emerging great masquerader.

BMJ Case Rep 2018 Dec 22;11(1). Epub 2018 Dec 22.

Department of Medicine, Divisions of Pulmonary, Critical Care Medicine and Infectious Diseases, Columbia, Missouri, USA.

A 49-year-old Caucasian woman presented with subacute headache and right eye pain associated with scotoma, blurred vision and photophobia. MRI was suggestive of optic neuritis of the right optic nerve and she was treated with steroids. Due to persistent symptoms, a lumbar puncture was performed and cerebrospinal fluid analysis was positive for venereal disease research laboratory and rapid plasma reagin titres. Read More

View Article

Download full-text PDF

Source
http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22563
Publisher Site
http://dx.doi.org/10.1136/bcr-2018-225635DOI Listing
December 2018
13 Reads

Limited efficacy of nontreponemal test combined with treponemal test in the initial syphilis screening algorithm.

J Med Microbiol 2019 Feb 20;68(2):216-220. Epub 2018 Dec 20.

1​Department of Bacteriology, Centre de Biologie Humaine, Centre Hospitalo-Universitaire Amiens Picardie, Amiens, France.

Purpose: Various syphilis screening algorithms have been proposed and are now used by many clinical laboratories following the introduction of automated treponemal tests (TTs). In France, the diagnosis of syphilis is based on a TT combined with a nontreponemal test (NTT). The objective of this study was to evaluate the diagnostic impact of NTT on initial syphilis screening at the Amiens University Hospital between January 2013 and December 2016. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1099/jmm.0.000886DOI Listing
February 2019
1 Read

Acute subretinal abscess in septicaemia with endophthalmitis showcased by multimodal retinal imaging and with 2-year follow-up.

BMJ Case Rep 2018 11 28;11(1). Epub 2018 Nov 28.

Department of Ophthalmology, Royal Bolton Hospital NHS Foundation Trust, Bolton, UK.

A middle-aged man presented to emergency services with central vision loss in the setting of flu-like illness with fever. A striking subfoveal abscess was observed in the right fundus. Focal acute chorioretinal inflammation was noted in the asymptomatic fellow eye. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2018-227288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301446PMC
November 2018

Modelling the risk of transfusion-transmitted syphilis: a reconsideration of blood donation testing strategies.

Vox Sang 2019 Feb 18;114(2):107-116. Epub 2018 Dec 18.

Centre for International Economics, Sydney, NSW, Australia.

Background And Objectives: Donor syphilis testing began in the 1940s amidst widespread transfusion-transmitted syphilis (TTS). Since then, the introduction of penicillin, pre-donation screening questionnaires and improved storage conditions have contributed to reducing transmission risk. Consequently, universal testing may no longer be cost-effective. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/vox.12741DOI Listing
February 2019
3 Reads

Trends in prevalence of HIV and syphilis in a central blood bank of Veracruz, Mexico.

Transfus Apher Sci 2019 Feb 8;58(1):94-99. Epub 2018 Dec 8.

Laboratorio de Biología Molecular, Centro Estatal de la Transfusión Sanguínea del Estado de Veracruz, Veracruz, Mexico; Facultad de Bioanálisis, Universidad Veracruzana, Veracruz, Veracruz, Mexico. Electronic address:

Syphilis and HIV infections continue to threaten the safety of blood banks in countries where altruistic donations are rare. The aim of this study of blood donors to the Centro Estatal de la Transfusion Sanguínea de Veracruz (Mexico) was to determine changes in the prevalence of syphilis and HIV, and to identify factors associated with these infections. A total of 109,054 blood donors were retrospectively analyzed from 2007 to 2014. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.transci.2018.12.001DOI Listing
February 2019
3 Reads

A spatiotemporal meta-analysis of HIV/syphilis epidemic among men who have sex with men living in mainland China.

BMC Infect Dis 2018 Dec 12;18(1):652. Epub 2018 Dec 12.

Dermatology Hospital, Southern Medical University, Guangzhou, 510095, Guangdong, China.

Background: Geographic differences in HIV, syphilis and condomless sex among men who have sex with men in China remained unknown. We aimed to elucidate these spatiotemporal changing patterns in China.

Methods: We conducted a spatiotemporal meta-analysis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12879-018-3532-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292157PMC
December 2018
2.613 Impact Factor

[HIV and syphilis infection and related medical treatment status of low-fee female sex workers in three provinces of China, 2012-2015].

Zhonghua Yu Fang Yi Xue Za Zhi 2018 Dec;52(12):1239-1242

Division of Propaganda Education and Prevention Intervention, National Center for AIDS/STD Control and Prevention, Chinese Center for Diseases Control and Prevention, Beijing 102206, China.

To understand the HIV and syphilis infection and related treatment status of low-fee female sex workers (FSWs) in 3 provinces of China. Four cross-sectional survey data of low-fee FSWs from six cities (counties) in Guangxi, Yunnan and Hunan Province between October 2012 and July 2015 were obtained from the national science and technology major special project intervention study for reducing sexually transmitted diseases (STDs) and acquired immunodeficiency syndrome (AIDS) in low-fee FSWs' database, which included social demographic characteristics, sexual service characteristics and related medical care seeking behaviors, etc. A total of 2 050 subjects were included in the database. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.issn.0253-9624.2018.12.009DOI Listing
December 2018

Congenital Conundrum.

Authors:
Sean Price

Tex Med 2018 Jul 1;114(7):42-43. Epub 2018 Jul 1.

Physicians fight Texas' stubborn rates of congenital infections. Syphillis, CMV, and HIV are the top three. Read More

View Article

Download full-text PDF

Source

Liaison leads to solitary syphilitic chancre on the neck.

Lancet 2018 12;392(10162):2397

Department of Dermatology, Venereology, and Allergy, University Medical Center and Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0140-6736(18)32620-5DOI Listing
December 2018
1 Read

Jarisch-Herxheimer reaction in a patient with syphilis and human immunodeficiency virus infection.

Rev Soc Bras Med Trop 2018 Nov-Dec;51(6):877-878

Programa de Pós-Graduação Stricto Sensu em Ciências da Saúde, Universidade Federal do Maranhão, São Luís, MA, Brasil.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/0037-8682-0419-2017DOI Listing
February 2019
3 Reads

Syphilis in pregnancy, congenital syphilis, and factors associated with mother-to-child transmission in Itapeva, São Paulo, 2010 to 2014.

Rev Soc Bras Med Trop 2018 Nov-Dec;51(6):819-826

Departamento de Moléstias Infecciosas e Parasitárias, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brasil.

Introduction: This study describes cases of syphilis in pregnancy (SiP) and congenital syphilis (CS) and identifies factors associated with mother-to-child transmission in patients in Itapeva from January 1, 2010 to December 31, 2014.

Methods: Using SiP and CS notification forms and medical records, a cross-sectional study involving 149 pregnant women was conducted.

Results: Annual SiP detection rates ranged from 16. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/0037-8682-0377-2017DOI Listing
February 2019
2 Reads

Prevalence and risk factors of syphilis and human immunodeficiency virus co-infection at a university hospital in Brazil.

Rev Soc Bras Med Trop 2018 Nov-Dec;51(6):813-818

Departamento de Medicina Tropical, Universidade Federal de Pernambuco, Recife, PE, Brasil.

Introduction: The incidence of syphilis has increased since the 1970s.

Methods: This was a descriptive and analytical cross-sectional study with a non-probabilistic sample.

Results: Of 973 patients with human immunodeficiency virus, 179 (18. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/0037-8682-0097-2018DOI Listing
February 2019
4 Reads

Prioritizing surveillance activities for certification of yaws eradication based on a review and model of historical case reporting.

PLoS Negl Trop Dis 2018 12 4;12(12):e0006953. Epub 2018 Dec 4.

Institute of Tropical Medicine, Antwerp, Belgium.

Background: The World Health Organization (WHO) has targeted yaws for global eradication. Eradication requires certification that all countries are yaws-free. While only 14 Member States currently report cases to WHO, many more are known to have a history of yaws and some of them may have ongoing transmission. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pntd.0006953DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294396PMC
December 2018
15 Reads

Congenital Syphilis and the Prozone Phenomenon: A Case Study.

Authors:
Lauren E Spydell

Adv Neonatal Care 2018 Dec;18(6):446-450

Neonatal Intensive Care Unit, Rady Children's Hospital, San Diego, California.

Background: There is a global rise in maternal syphilis and infants born with congenital syphilis.

Clinical Findings: This case report presents a 32-week gestation premature male infant with initial clinical findings significant for respiratory failure as well as blueberry muffin spot rash and hepatosplenomegaly, which are consistent with congenital syphilis.

Primary Diagnosis: This case study is unique in that the diagnosis of congenital neurosyphilis was demonstrated despite negative maternal serology because of the prozone phenomenon. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/ANC.0000000000000573DOI Listing
December 2018
14 Reads