2,611 results match your criteria Encephalopathy Hypertensive


[Features of cerebral venous hemodynamic in patients with hypertensive encephalopathy].

Zh Nevrol Psikhiatr Im S S Korsakova 2020 ;120(5):37-41

Tashkent Pediatric Medical Institute, Tashkent, Uzbekistan.

Objective: To study the characteristics of main clinical and diagnostic indicators of cerebral venous circulation and their dynamics in patients with hypertensive encephalopathy of various stages treated with cytoflavin.

Material And Methods: Clinical and instrumental data of the examination of 105 patients with the established diagnosis of hypertensive encephalopathy of various stages were analyzed. Cerebral hemodynamics was investigated using transcranial duplex scanning of the veins and sinuses of the brain. Read More

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http://dx.doi.org/10.17116/jnevro202012005137DOI Listing
January 2020

Transjugular Intrahepatic Portosystemic Shunts: Advances and New Uses in Patients with Chronic Liver Disease.

Clin Liver Dis 2020 Aug 31;24(3):373-388. Epub 2020 May 31.

Hepatology Program, Department of Medicine, Northwestern Feinberg School of Medicine, Chicago, IL, USA.

Transjugular intrahepatic portosystemic shunts is an established treatment for portal hypertensive complications. Advancements in technology and technique have led to novel indications, including treatment of chronic portal vein thrombosis and use before abdominal surgery to alleviate portal hypertensive complications. Use of TIPS can facilitate the embolization of large portal-systemic shunts to alleviate refractory hepatic encephalopathy owing to excessive portal shunting. Read More

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http://dx.doi.org/10.1016/j.cld.2020.04.007DOI Listing

Significant improvement in portal-systemic liver failure symptoms and successful management of portal-splenic venous hemodynamics by the combination of interventional radiology and pharmacotherapy.

Hepatol Res 2020 Jul 1. Epub 2020 Jul 1.

Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube-Yamaguchi, 7558505, Japan.

Aim: To describe a case of hepatitis C virus-related decompensated cirrhosis with portal-systemic liver failure and refractory encephalopathy that was successfully managed with a combination of interventional radiology and pharmacotherapy to improve hepatic function including hyperammonemia and to control portal-splenic venous hemodynamics with hepatic venous pressure gradient (HVPG) monitoring.

Case Presentation: A man in his late 50s presented with a Child-Pugh score of 13, Model for End-Stage Liver Disease-sodium (MELD-Na) score of 19, and blood ammonia level of 185 μg/dL. He underwent balloon-occluded retrograde transvenous obliteration (BRTO) followed by partial splenic embolization (PSE) and non-selective beta-blocker (NSBB) administration. Read More

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http://dx.doi.org/10.1111/hepr.13545DOI Listing

Posterior Reversible Encephalopathy Syndrome Following Failure of Conservative Management in Renal Trauma: Case Report.

Urology 2020 Jun 10. Epub 2020 Jun 10.

Maine Medical Center Department of Urology, Tufts University School of Medicine.

Blunt renal trauma is relatively common in children. Conservative management has become the mainstay of treatment. A 4-year-old boy presented following a fall onto his right abdomen resulting in renal trauma. Read More

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http://dx.doi.org/10.1016/j.urology.2020.05.059DOI Listing

Cerebellar Parieto-occipital Posterior Reversible Encephalopathy Syndrome and Cerebral Metamorphopsia Associated with Asymptomatic Atrial Septum Vegetation and Renal Disease: Case Report.

Am J Case Rep 2020 Jun 9;21:e923441. Epub 2020 Jun 9.

Department of Medicine, Tripler Army Medical Center, Honolulu, HI, USA.

BACKGROUND Posterior reversible encephalopathy syndrome (PRES) is a poorly characterized and enigmatic syndrome. Despite consistently presenting with nervous system vasogenic edema, this malady has been associated with variable triggers, neurological symptoms, and natural history. CASE REPORT The report presents a 25-year old African American female who presented with altered mental status and bilateral cortical blindness. Read More

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http://dx.doi.org/10.12659/AJCR.923441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304656PMC

Mid-Aortic Syndrome: A Rare Cause of Renovascular Hypertension in Childhood Treated Percutaneously with an Unusual Vascular Access.

Curr Pediatr Rev 2020 06 9. Epub 2020 Jun 9.

Azienda Ospedaliero Universitaria Policlinico, Pediatric Hospital Giovanni XXIII, Pediatric Nephrology and dialysis Unit, Bari. Italy.

Introduction: Mid-Aortic Syndrome (MAS) is a rare vascular malformation characterized by segmental narrowing of the abdominal aorta and stenosis of its principal branches. Patients affected by MAS typically present malignant renovascular hypertension, with variable clinical symptoms like claudication, abdominal angina and headache. Moreover, they can develop complications such as hypertensive encephalopathy, congestive heart failure and vascular brain accidents. Read More

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http://dx.doi.org/10.2174/1573396316666200609170003DOI Listing

Hypertensive emergencies and urgencies in emergency departments: a systematic review and meta-analysis.

J Hypertens 2020 Jul;38(7):1203-1210

Hypertension Unit, Division of Internal Medicine, Department of Medical Sciences, AO 'Città della Salute e della Scienza' University Hospital, Turin.

Objectives: The prevalence of hypertensive emergencies and urgencies and of acute hypertension-mediated organ damage (aHMOD) in emergency departments is unknown. Moreover, the predictive value of symptoms, blood pressure (BP) levels and cardiovascular risk factors to suspect the presence of aHMOD is still unclear. The aim of this study was to investigate the prevalence of hypertensive emergencies and hypertensive urgencies in emergency departments and of the relative frequency of subtypes of aHMOD, as well as to assess the clinical variables associated with aHMOD. Read More

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http://dx.doi.org/10.1097/HJH.0000000000002372DOI Listing

High rate of hypertension in patients with m.3243A>G MELAS mutations and POLG variants.

Mitochondrion 2020 Jun 2;53:194-202. Epub 2020 Jun 2.

Biomedical Physiology & Kinesiology, Simon Fraser University, Burnaby, Canada; Centre for Cell Biology, Development, and Disease, Simon Fraser University, Burnaby, BC, Canada. Electronic address:

Animal studies suggest that decreased vascular mitochondrial DNA copy number can promote hypertension. We conducted a chart review of blood pressure and hemodynamics in patients with either mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS, n = 36) or individuals with variants in the mitochondrial DNA polymerase gamma (POLG, n = 26). The latter included both pathogenic variants and variants of unknown significance (VUS). Read More

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http://dx.doi.org/10.1016/j.mito.2020.05.011DOI Listing

Severe pre-eclamptic women with headache: is posterior reversible encephalopathy syndrome an associated concurrent finding?

BMC Pregnancy Childbirth 2020 Jun 1;20(1):336. Epub 2020 Jun 1.

Department of Obstetrics & Gynecology, Chang Gung Memorial Hospital and Chang Gung University, 5, Fu-Shin street, Kei-Shan, Tao-Yuan, 333, The People's Republic of China.

Background: A high incidence of posterior reversible encephalopathy syndrome (PRES) has been observed in women with eclampsia on imaging. However this association was documented mostly after convulsions occurred. This study aimed to detect the development of PRES using magnetic resonance imaging (MRI) in women with severe preeclampsia and headache, and evaluate the clinical and radiological findings in obstetric outcomes. Read More

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http://dx.doi.org/10.1186/s12884-020-03017-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268303PMC

Posterior reversible encephalopathy syndrome (PRES) as a neurological association in severe Covid-19.

J Neurol Sci 2020 07 23;414:116943. Epub 2020 May 23.

Division of Neurology, Mount Auburn Hospital, Harvard Medical School, Cambridge, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2020.116943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245308PMC

[Medicaments and oral healthcare. Hyperpigmentation of oral soft tissues due to afamelanotide].

Ned Tijdschr Tandheelkd 2020 Apr;127(4):237-243

The medicament afamelanotide is an analogue of endogenous ?-melanocyte-stimulating hormone. It promotes cutaneous pigmentation, providing protection from sunlight. In dermatology, afamelanotide seems to establish therapeutic results for polymorphic light eruption, solar urticaria, erythropoietic protoporphyria, Hailey-Hailey disease, vitiligo and acne vulgaris. Read More

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http://dx.doi.org/10.5177/ntvt.2020.04.19115DOI Listing

CASPR2 autoimmunity in children expanding to mild encephalopathy with hypertension.

Neurology 2020 Jun 18;94(22):e2290-e2301. Epub 2020 May 18.

From the Division of Pediatric Epileptology (S. Syrbe), Centre for Paediatrics and Adolescent Medicine, University Hospital Heidelberg, Germany; Division of Pediatric Neurology (G.M.S., R.S.), University Children's Hospital Zurich; Department of Neurology (J.B., R.I.F.), University & University Hospitals of Geneva, Switzerland; Division of Pediatric Neurology (I.B.), Developmental Neurology and Social Pediatrics, Department of Pediatrics and Epilepsy Center for Children, Adolescents and Adults, University Hospital LMU Munich; Laboratory Krone (C.I.B., C.G.B.), Bad Salzuflen; Department of Pediatrics and Pediatric Neurology (P.H.), Faculty of Medicine, Georg August University, Goettingen; Department of Child Neurology (J.K., A.W.), University Children's Hospital, Tuebingen; Epilepsy Center Bethel (T.P., C.G.B.), Krankenhaus Mara, Bielefeld, Germany; Clinic of Immunology (E.P.-M.), University Hospital Zurich; Kantonsspital Graubünden (S. Schmid, S. Strozzi), Chur; Pediatric Nephrology Unit (M.W.), University Children's Hospital Zurich, Switzerland; Division of Child Neurology and Metabolic Medicine (A.Z.), Centre for Paediatrics and Adolescent Medicine, University Hospital Heidelberg; Institute of Clinical Chemistry (K.-P.W., F.L.), Neuroimmunology Section, University Hospital Schleswig-Holstein Kiel/Lübeck; Department of Neurology (K.-P.W.), University of Lübeck; and Department of Neurology (F.L.), Christian-Albrechts-University Kiel, Germany.

Objective: To delineate autoimmune disease in association with contactin-associated protein 2 (CASPR2) antibodies in childhood, we reviewed the clinical phenotype of children with CASPR2 antibodies.

Methods: Retrospective assessment of patients recruited through laboratories specialized in autoimmune CNS disease.

Results: Ten children with serum CASPR2 antibodies were identified (age at manifestation 18 months to 17 years). Read More

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http://dx.doi.org/10.1212/WNL.0000000000009523DOI Listing

Etiology, Diagnosis and Management of Aortitis.

Cardiovasc Intervent Radiol 2020 May 10. Epub 2020 May 10.

Department of Cardiovascular Radiology and Endovascular Interventions, All India Institute of Medical Sciences, New Delhi, 110029, India.

Aortitis includes conditions with infectious or non-infectious etiology, characterized by inflammatory changes in one or more layers in aortic wall. Age at onset, geographic predilections, distribution and pattern of involvement in aorta, its branches and pulmonary arteries, and systemic associations provide a clue to etiology. Clinical presentations are often non-specific. Read More

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http://dx.doi.org/10.1007/s00270-020-02486-6DOI Listing
May 2020
1.965 Impact Factor

Peak blood pressure and prediction of posterior reversible encephalopathy syndrome in children.

Pediatr Nephrol 2020 May 8. Epub 2020 May 8.

Section of Nephrology, Department of Pediatrics, Wake Forest School of Medicine and Brenner Children's Hospital, One Medical Center Boulevard, Winston Salem, NC, 27157, USA.

Background: Hypertension is a risk factor for posterior reversible encephalopathy syndrome (PRES), but the timing and severity of hypertension relative to PRES are unknown. The objective was to identify a clinically meaningful blood pressure (BP) threshold that predicts PRES development in high-risk children.

Methods: We recorded peak systolic BP, diastolic BP, BP z-scores, and mean arterial pressure over the 14 days preceding clinical concern for PRES in 35 subjects who developed PRES, compared to 14 controls who had normal brain magnetic resonance imaging and similar underlying disease, renal function, and medications. Read More

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http://dx.doi.org/10.1007/s00467-020-04577-5DOI Listing

Posterior Reversible Encephalopathy Syndrome Due to Acute Water Intoxication in a Patient with Schizophrenia.

Int Med Case Rep J 2020 7;13:117-121. Epub 2020 Apr 7.

Department of Psychiatry, Tokyo Women's Medical University, Tokyo, Japan.

Posterior reversible encephalopathy syndrome (PRES) is a clinical syndrome that presents as transient cerebral edema (vasogenic edema), usually on a background of hypertensive encephalopathy, puerperal eclampsia, or immunosuppressant drug use. We describe a case of PRES that arose in the context of a psychiatric disorder. The patient was a 26-year-old woman with schizophrenia who was hospitalized upon falling into a catatonic stupor and then suffered acute anxiety leading to impulsive polydipsia and subsequent water intoxication. Read More

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http://dx.doi.org/10.2147/IMCRJ.S237430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150669PMC

Cognitive disorders in persons of working age with dyscirculatory encephalopathy.

Wiad Lek 2020 ;73(3):449-453

Ukrainian Medical Stomatological Academy, Poltava, Ukraine.

Objective: The aim of the study was to study the neuropsychological features of cerebrovascular disorders in persons of working age at the outpatient clinic stage.

Patients And Methods: Materials and methods: 90 persons of working age were surveyed. Clinical neurological and clinical instrumental examination. Read More

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Psychiatric Morbidity and Its Prognosis in Posterior Reversible Encephalopathy Syndrome.

J Neuropsychiatry Clin Neurosci 2020 Apr 14:appineuropsych19080184. Epub 2020 Apr 14.

Department of Health Service and Population Research, Section of Women's Mental Health, Institute of Psychiatry, Psychology and Neuroscience, King's College London (Keynejad); and UCL Institute of Mental Health, Division of Psychiatry, Faculty of Brain Sciences, University College London, London (David).

Posterior reversible encephalopathy syndrome (PRES) is a clinically and radiologically diagnosed disorder distinguished by subcortical vasogenic cerebral edema. To date, its presentation has been described through summarized neurological categories, such as seizures, headaches, "confusion," and "altered mental function." This retrospective case series identified all cases of clinically confirmed, radiologically diagnosed PRES resulting in treatment in a large teaching hospital from 2010 to 2019. Read More

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http://dx.doi.org/10.1176/appi.neuropsych.19080184DOI Listing

as an Initiating Factor of Complications in Patients With Cirrhosis: A Single-Center Observational Study.

Front Med (Lausanne) 2020 24;7:96. Epub 2020 Mar 24.

Medical Microbiology and Immunology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

The relationship between liver cirrhosis and () is a debatable matter. The aim of this study is to evaluate the possible association between infection and liver cirrhosis. A single-center prospective cohort pilot study of 558 patients with cirrhosis was followed up for 1 year. Read More

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http://dx.doi.org/10.3389/fmed.2020.00096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105722PMC

Clinical and MRI Features of Posterior Reversible Encephalopathy Syndrome With Atypical Regions: A Descriptive Study With a Large Sample Size.

Front Neurol 2020 24;11:194. Epub 2020 Mar 24.

Department of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Accurate diagnosis and timely treatment for posterior reversible encephalopathy syndrome (PRES) with atypical regions are very important in clinical practice. However, until now, little has been known about the clinical and MRI manifestations of this disease. Therefore, the aim of this study is to investigate the clinical and MRI features of PRES to promote clinical management and deepen our understanding of this disease. Read More

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http://dx.doi.org/10.3389/fneur.2020.00194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105821PMC

Cortical Laminar Necrosis as a Result of Status Epilepticus After Resection of Parafalcal Meningioma.

Surg Technol Int 2020 May;36:159-177

Neurosurgery Unit, IRCCS Fondazione Policlinico San Matteo, Pavia, Italy.

Status epilepticus during the post-operative period is a rare complication for neurosurgery patients. Acute encephalopathic syndromes can present a diagnostic challenge due to the wide range of possible etiologies, and can also have vastly different outcomes. Posterior reversible encephalopathy syndrome is a rare neurological disorder, usually associated with specific medical conditions, that causes a disturbance of CNS homeostasis, while cortical laminar necrosis (CLN) is an unusual type of infarction characterized by selective necrosis of the cerebral cortex with sparing of the white matter. Read More

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Treatment of recurrent severe hepatic encephalopathy in patients with large porto-collaterals shunts or transjugular portosystemic shunt.

Acta Gastroenterol Belg 2020 Jan-Mar;83(1):67-71

Department of Gastroenterology and Hepatology, University Hospitals KULeuven, Belgium.

Patients with hepatic encephalopathy (HE) do not systematically receive priority on the waiting list for liver transplantation. In some patients with cirrhosis, excessive amounts of gut derived ammonia can bypass the liver parenchyma due to large spontaneous portosystemic shunts (SPSS) induced by portal hypertension. A similar but iatrogenic condition can occur after transjugular portosystemic shunt (TIPS) insertion. Read More

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[POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME IN CHILDREN (CASE REPORT)].

Georgian Med News 2020 Jan(298):46-49

Ivano-Frankivsk National Medical University, 2Department of Pediatric Surgery, Ukraine.

Posterior reversible encephalopathy is a rare clinical and radiological syndrome with a character type of change in the brain: vasogenic edema of the white matter, mainly in the occipital and parietal lobes, usually symmetric, which is a secondary manifestation of acute dysfunction of the posterior cerebrovascular system. The main pathophysiological mechanism of PRES is a violation of tone of cerebral vessels. Hyperactivity of sympathetic NS, oxidative stress, development of endothelial dysfunction, disorders of humoral homeostasis, particularly, interaction between a number of biochemical substances can trigger the last one. Read More

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January 2020

The determinants of neurological phenotypes during acute hypertensive crises - a preliminary study.

Neurol Res 2020 May 2;42(5):398-404. Epub 2020 Mar 2.

Department of Neurology, Hacettepe University, Ankara, Turkey.

: Acute blood pressure elevations lead to wide spectrum of neurologic manifestations, ranging from no overt neurologic symptoms to catastrophic events like ICH. Little is known regarding the determinants of this clinical variability. We determined clinical and imaging features of hypertensive crisis patients with normal neurological examination, ICH and posterior reversible encephalopathy syndrome (PRES). Read More

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http://dx.doi.org/10.1080/01616412.2020.1735121DOI Listing

Posterior Reversible Encephalopathy Syndrome: Clinical Features and Outcome.

Authors:
Archana Hinduja

Front Neurol 2020 14;11:71. Epub 2020 Feb 14.

Department of Neurology, The Ohio State University Wexner Medical Center, Columbus, OH, United States.

Posterior reversible encephalopathy syndrome (PRES) is an acute neurotoxic syndrome that is characterized by a spectrum neurological and radiological feature from various risk factors. Common neurological symptoms includes headache, impairment in level of consciousness, seizures, visual disturbances, and focal neurological deficits. Common triggering factors include blood pressure fluctuations, renal failure, eclampsia, exposure to immunosuppressive or cytotoxic agents and autoimmune disorders. Read More

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http://dx.doi.org/10.3389/fneur.2020.00071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034490PMC
February 2020

Posterior Reversible Encephalopathy Syndrome in Clinical Toxicology: A Systematic Review of Published Case Reports.

Front Neurol 2019 12;10:1420. Epub 2020 Feb 12.

Université de Tours, INSERM, Centre d'Étude des Pathologies Respiratoires (CEPR)-UMR 1100, CHRU de Tours, Service de Médecine Intensive Réanimation, CIC 1415, Réseau CRICS-TRIGGERSEP, Tours, France.

Posterior reversible encephalopathy syndrome (PRES) is a rare clinical and radiological entity characterized by a typical brain edema. Although several case reports have described PRES in a context of poisoning, to our knowledge, a comprehensive assessment has not been performed. The aim of this systematic review was to raise awareness on poisoning-specific PRES features and to encourage consistent and detailed reporting of substance abuse-and drug overdose-associated PRES. Read More

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http://dx.doi.org/10.3389/fneur.2019.01420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029435PMC
February 2020

Lower Gastrointestinal Bleeding in Patients With Cirrhosis-Etiology and Outcomes.

Am J Med Sci 2020 04 15;359(4):206-211. Epub 2020 Jan 15.

Department of Internal Medicine, Medical University of South Carolina, Charleston, South Carolina. Electronic address:

Background: Lower gastrointestinal bleeding (LGIB) is a common clinical problem, and may be more prevalent among patients with cirrhosis, especially in the setting of portal hypertension and coagulopathy. However, there is extremely little data available on the subject of LGIB in patients with cirrhosis. Therefore, the primary objective of this study was to better understand the etiology and outcomes of cirrhotic patients hospitalized with LGIB. Read More

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http://dx.doi.org/10.1016/j.amjms.2020.01.007DOI Listing

Concurrent pituitary apoplexy and posterior reversible encephalopathy syndrome in a patient with end-stage renal disease on hemodialysis: A case report.

Medicine (Baltimore) 2020 Jan;99(5):e18987

Department of Internal Medicine, HANSUNG Union Internal Medicine Clinic and Dialysis Center, Daegu, Republic of Korea.

Rationale: Pituitary apoplexy (PA) and posterior reversible encephalopathy syndrome (PRES) are rare neurologic diseases that show acute neuro-ophthalmologic symptoms such as headache, decreased visual acuity, and altered consciousness. These diseases are rarely found in patients with end-stage renal disease (ESRD) on hemodialysis, and simultaneous occurrence of these 2 diseases has not been reported.

Patient Concerns: The patient was a 75-year-old man with a history of hypertension, diabetes mellitus, and non-functioning pituitary macroadenoma. Read More

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http://dx.doi.org/10.1097/MD.0000000000018987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004754PMC
January 2020

Long-term Outcomes and Health Perceptions in Pediatric-onset Portal Hypertension Complicated by Varices.

J Pediatr Gastroenterol Nutr 2020 May;70(5):628-634

Section of Pediatric Surgery, Pediatric Liver and Gut Research Group, Pediatric Research Center, Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Objectives: Outcomes of pediatric-onset portal hypertension are poorly defined. We aimed to assess population-based long-term outcomes of pediatric-onset portal hypertension complicated by varices.

Methods: All children with esophageal varices (n = 126) were identified from 14,144 single nationwide referral center endoscopy reports during 1987 to 2013, and followed up through national health care and death registers. Read More

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http://dx.doi.org/10.1097/MPG.0000000000002643DOI Listing

PRES-like presentation in MOG antibody-related demyelination (MARD).

J Clin Neurosci 2020 Feb 22;72:453-455. Epub 2020 Jan 22.

Department of Neurology, Gold Coast University Hospital, Southport, QLD 4215, Australia; School of Medicine, Griffith University, Gold Coast Campus, QLD 4222, Australia.

A 33-year-old male presented with a progressive four-week history of frontal headache and left visual field impairment. MRI brain confirmed bilateral, asymmetric, occipital vasogenic oedema, suggestive of posterior reversible encephalopathy syndrome (PRES). Serum testing for MOG antibodies was positive, confirming a diagnosis of MOG antibody-related demyelination (MARD). Read More

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http://dx.doi.org/10.1016/j.jocn.2020.01.034DOI Listing
February 2020

Posterior reversible encephalopathy syndrome with ischemic infarction complicated with intrauterine fetal death: A case report.

Medicine (Baltimore) 2020 Jan;99(4):e18877

Department of Neurology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.

Rationale: Posterior reversible encephalopathy syndrome (PRES), a rare neurologic disorder, manifests as headache, altered mental status, seizures, visual disturbances, and other focal neurologic signs with typically reversible clinical symptoms and image changes. Although the underlying mechanism remains unknown, a current theory indicates cerebral autoregulation failure as the primary cause. We report a case of PRES with stroke in an adult with intrauterine fetal death (IUFD). Read More

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http://dx.doi.org/10.1097/MD.0000000000018877DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004726PMC
January 2020

Posterior Reversible Encephalopathy Syndrome After 90Y-Resin Microspheres Radioembolization.

Clin Nucl Med 2020 Mar;45(3):202-203

From the Departments of Nuclear Medicine.

A 66-year-old man with colorectal carcinoma and liver-only metastases underwent radioembolization using Y-loaded, resin-based microspheres. One day after radioembolization, the patient experienced severe hypertension and multiple seizures. On MRI, symmetric edematous areas in the cerebellum and the parietal and occipital lobe were observed, a typical finding for posterior reversible encephalopathy syndrome (PRES). Read More

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http://dx.doi.org/10.1097/RLU.0000000000002933DOI Listing

Case Report: Subacute Sclerosing Panencephalitis in Pregnancy Mimicking Posterior Reversible Encephalopathy Syndrome.

Am J Trop Med Hyg 2020 03;102(3):634-636

Department of Neurology, King George Medical University (KGMU), Lucknow, India.

In posterior reversible encephalopathy syndrome, brain magnetic resonance imaging (MRI) reveals bilateral occipital, parietal, and subcortical white matter hyperintensities on T2/fluid-attenuated inversion recovery (FLAIR) sequences. After treatment, imaging abnormalities are usually reversible. Eclampsia is the most frequent cause of posterior reversible encephalopathy syndrome in pregnancy. Read More

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http://dx.doi.org/10.4269/ajtmh.19-0901DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056428PMC

Posterior Reversible Encephalopathy Syndrome: Pattern on F-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography Correlated with Magnetic Resonance Imaging in Pediatric Hypertensive Encephalopathy.

Indian J Nucl Med 2020 Jan-Mar;35(1):72-73. Epub 2019 Dec 31.

Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.

Posterior reversible encephalopathy syndrome (PRES) is characterized clinically by headache, seizures, vomiting, altered mental status, and blurred vision. However, with overlapping and atypical clinical symptoms, PRES becomes a diagnostic challenge. We describe the imaging findings of PRES in magnetic resonance imaging and F-fluorodeoxyglucose positron emission tomography-computed tomography in an 11-year-old child who presented with features of hypertensive encephalopathy. Read More

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http://dx.doi.org/10.4103/ijnm.IJNM_149_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958944PMC
December 2019

Transjugular intrahepatic portosystemic shunt (TIPS): current indications and strategies to improve the outcomes.

Intern Emerg Med 2020 01 9;15(1):37-48. Epub 2020 Jan 9.

Department of Experimental and Clinical Medicine, University of Florence, Viale Morgagni 85, 50134, Florence, Italy.

Transjugular intrahepatic portosystemic shunt (TIPS) represents a very effective treatment of complications of portal hypertension. Established indications to TIPS in cirrhotic patients include portal hypertensive bleeding and refractory ascites. Over the years additional indications have been proposed, such as the treatment of vascular disease of the liver, hepatic hydrothorax, hepatorenal syndrome and bleeding from ectopic varices. Read More

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http://dx.doi.org/10.1007/s11739-019-02252-8DOI Listing
January 2020
2.624 Impact Factor

Clinical Profile and Immediate Outcome of Children Admitted With Acute Glomerulonephritis in Pediatrics Department of A Tertiary Level Hospital.

Mymensingh Med J 2020 Jan;29(1):5-15

Dr Mowmita Sharmin, Registrar, Department of Pediatrics, Mymensingh Medical College Hospital, Mymensingh, Bangladesh.

Acute post-streptococcal glomerulonephritis (APSGN) is the commonest cause of acute glomerulonephritis (AGN), which usually present with gross hematuria, mild edema, oliguria, hypertension and varying degree of renal insufficiency. It is more common among the population of school going age where poverty, overcrowding and poor hygienic conditions are prevailing. This cross sectional observational study was aimed to know the socio-demographic variables, clinical profile and immediate outcome of AGN in hospitalized children and was conducted in the Pediatric department of Mymensingh Medical College Hospital (MMCH), Mymensingh, Bangladesh from November 2014 to April 2015. Read More

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January 2020

Brainstem Posterior Reversible Encephalopathy Syndrome in an Asymptomatic Patient.

Can J Neurol Sci 2020 Mar;47(2):267-269

Department of Medical and Surgical Sciences, Institute of Neurology, Magna Græcia University, Catanzaro, Italy.

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http://dx.doi.org/10.1017/cjn.2020.2DOI Listing

Acute Intermittent Porphyria: A rare cause of hyponatraemia.

Malays J Pathol 2019 Dec;41(3):369-372

University Malaya, Faculty of Medicine, Department of Pathology, Kuala Lumpur, Malaysia.

Introduction: Hyponatraemia is one of the most frequent laboratory findings in hospitalised patients. We present an unusual case of hyponatraemia in a 23-year-old female secondary to acute intermittent porphyria (AIP), a rare inborn error of metabolism.

Case Report: The patient presented with upper respiratory tract infection, fever, seizures and abdominal pain. Read More

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December 2019

Balloon-occluded Retrograde Transvenous Obliteration Versus Transjugular Intrahepatic Portosystemic Shunt for Gastric Varices: A Meta-Analysis.

J Clin Gastroenterol 2019 Dec 23. Epub 2019 Dec 23.

Department of Radiology, University of Kentucky, Lexington, KY.

Introduction: Balloon-occluded retrograde transvenous obliteration (BRTO) and transjugular intrahepatic portosystemic shunt (TIPS) are well-validated techniques in the management of portal hypertensive gastric variceal bleeding when medical management alone is not sufficient. However, despite their effectiveness, the adverse effects from both procedures make each technique more suitable to different cohorts of patient's depending on presence or lack of certain comorbidities. This study aims to compare clinical outcomes of patients who have undergone both procedures for portal hypertensive gastric variceal bleeding. Read More

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http://dx.doi.org/10.1097/MCG.0000000000001305DOI Listing
December 2019

Blood-Brain Barrier Disruption as a Potential Target for Therapy in Posterior Reversible Encephalopathy Syndrome: Evidence From Multimodal MRI in Rats.

Front Neurol 2019 26;10:1211. Epub 2019 Nov 26.

Department of Radiology, Affiliated Hospital of Guizhou Medical University, Guiyang, China.

To explore blood-brain barrier disruption in hypertensive posterior reversible encephalopathy syndrome. The hypertension rat models were successfully established and scanned on 7T micro-MRI. MRI parameter maps including apparent diffusion coefficient, T1 value, and perfusion metrics such as cerebral blood volume, cerebral blood flow, mean transit time and time to peak maps, were calculated. Read More

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http://dx.doi.org/10.3389/fneur.2019.01211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901929PMC
November 2019

[Stingray injury: A case in French Polynesia].

Ann Dermatol Venereol 2020 Feb 5;147(2):123-126. Epub 2019 Dec 5.

Service de médecine interne et polyvalente, centre hospitalier de Polynésie française, 98713 Pirae, Tahiti, Polynésie française. Electronic address:

Introduction: Stingray injuries occur when people inadvertently step on these fish. Penetration of the barb results in puncture and/or laceration wounds and lesions related to the venom.

Patients And Methods: We report the case of a 76-year-old woman in French Polynesia who was stung on her right ankle by a stingray. Read More

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http://dx.doi.org/10.1016/j.annder.2019.10.021DOI Listing
February 2020

Activation of the G Protein-Coupled Estrogen Receptor (GPER) Increases Neurogenesis and Ameliorates Neuroinflammation in the Hippocampus of Male Spontaneously Hypertensive Rats.

Cell Mol Neurobiol 2020 Jul 29;40(5):711-723. Epub 2019 Nov 29.

Laboratory of Neuroendocrine Biochemistry, Instituto de Biología y Medicina Experimental, Vuelta de Obligado 2490, 1428, Buenos Aires, Argentina.

It is known that spontaneously hypertensive rats (SHR) present a marked encephalopathy, targeting vulnerable regions such as the hippocampus. Abnormalities of the hippocampus of SHR include decreased neurogenesis in the dentate gyrus (DG), partial loss of neurons in the hilus of the DG, micro and astrogliosis and inflammation. It is also known that 17β-estradiol (E2) exert neuroprotective effects and prevent hippocampal abnormalities of SHR. Read More

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http://dx.doi.org/10.1007/s10571-019-00766-5DOI Listing

A PRESing case of visual changes and confusion.

Am J Emerg Med 2020 02 17;38(2):411.e1-411.e3. Epub 2019 Nov 17.

University of Minnesota, Department of Pediatrics, 2450 Riverside Avenue, Minneapolis, MN 55454, United States. Electronic address:

Visual disturbances are an uncommon pediatric chief complaint. Usually, after a complete ocular exam including visual acuity, most causes are benign and not life-threatening. Children with abnormal visual complaints who have underlying medical conditions, such as SLE or other autoimmune conditions, a recipient of a transplant, renal disease, and even eclampsia require closer scrutiny. Read More

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http://dx.doi.org/10.1016/j.ajem.2019.09.006DOI Listing
February 2020

Analysis of Clinical Symptoms and Brain MRI of Heat Stroke: 2 Case Reports and a Literature Review.

J Stroke Cerebrovasc Dis 2020 Feb 26;29(2):104511. Epub 2019 Nov 26.

Department of Neurology, Juntendo Urayasu Hospital, Urayasu-city, Chiba, Japan.

Introduction: Heat stroke is defined as high body temperature causing multiple organ failure, psychological change, seizure, and consciousness disturbance, which lead to its high mortality rate. However, the involvement of brain injury is rare, and heat-stroke has only been reported in a few case reports or case series. The purpose of this case study was to evaluate the clinical symptoms and radiological features of heat stroke. Read More

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2019.104511DOI Listing
February 2020

[Malignant arterial hypertension (HTAM) with severe systolic dysfunction of the reversible left ventricle].

Hipertens Riesgo Vasc 2020 Apr - Jun;37(2):82-85. Epub 2019 Nov 14.

Área Atención Integrada de Riesgo Vascular, Servicio de Medicina Interna, Sant Joan Despí Moisès Broggi-Hospital General Hospitalet, Consorci Sanitari Integral, Barcelona, España.

Malignant arterial hypertension is still present in current clinical care despite the fact that for more than three decades we have had a wide range of antihypertensive drugs to control high blood pressure. It is essential to know how to detect it in time due to its high risk to life, with poor short-term prognosis if not treated properly. It may present with nonspecific, but potentially serious, clinical symptoms or manifest clinically as a hypertensive emergency accompanied by hypertensive encephalopathy and multi-organ failure. Read More

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http://dx.doi.org/10.1016/j.hipert.2019.10.002DOI Listing
November 2019

Hypertensive brainstem encephalopathy: a diagnosis often overlooked.

Clin Med (Lond) 2019 Nov;19(6):511-513

Loh Guan Lye Specialist Centre, Penang, Malaysia.

Hypertensive encephalopathy (HE) is a subset of posterior reversible encephalopathy syndrome. It typically involves the posterior supratentorial structures, but variations do occur. However, isolated brainstem involvement in HE is rare, with a few cases reported in the literature. Read More

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http://dx.doi.org/10.7861/clinmed.2019-0247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899227PMC
November 2019

Imaging of Altered Mental Status.

Authors:
Alina Uzelac

Radiol Clin North Am 2020 Jan 18;58(1):187-197. Epub 2019 Oct 18.

Neuroradiology, Department of Radiology, Zuckerberg San Francisco General Hospital, University of California, 1001 Potrero Avenue, Room 1X56, San Francisco, CA 94110, USA. Electronic address:

Neuroimaging is an invaluable diagnostic tool for sorting through the vast array of etiologies that underlie altered mental status (AMS). Head computed tomography (CT) without contrast is the primary modality for evaluation of AMS and should be complemented by MR imaging in cases of negative CT but high clinical concern. Studies to maximize brain imaging efficiency and improve the yield of positive scans through the utilization of clinical and laboratory pre-scan diagnostics are ongoing. Read More

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http://dx.doi.org/10.1016/j.rcl.2019.08.002DOI Listing
January 2020

Reversible posterior leukoencephalopathy syndrome following apatinib for gastric cancer in an adult: A case report and a review of the literature.

Medicine (Baltimore) 2019 Nov;98(46):e17787

Weifang Medical University, P.R. China.

Rationale: Reversible posterior leukoencephalopathy syndrome (RPLS) is characterized by rapidly progressive hypertension, headache, and disturbance of consciousness. Moreover, RPLS is rarely reported after apatinib treatment.

Patient Concerns: We present a case of RPLS induced by apatinib in this report. Read More

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http://dx.doi.org/10.1097/MD.0000000000017787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867717PMC
November 2019

Variant Type of Posterior Reversible Encephalopathy Syndrome Associated with Deep Brain Hemorrhage: Case Report and Review of the Literature.

World Neurosurg 2020 Feb 8;134:176-181. Epub 2019 Nov 8.

Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Background: Various radiologic patterns of posterior reversible encephalopathy syndrome (PRES) have been reported. Among them, PRES involving brainstem, thalamus, or deep white matter and lacking parieto-occipital edema is rare. Although PRES in general has a benign course, PRES-related intracranial hemorrhage has been associated with a poor prognosis. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.10.196DOI Listing
February 2020