2,424 results match your criteria Encephalopathy Hypertensive


Isolated pontine involvement in posterior reversible encephalopathy syndrome with coincidental acute ischaemic stroke.

BMJ Case Rep 2019 Apr 16;12(4). Epub 2019 Apr 16.

DMOP, Basildon University Hospital, Basildon, Essex, UK.

Posterior reversible encephalopathy syndrome (PRES) is a cliniconeuroradiological syndrome characterised by a unique reversible pattern on imaging and total regression of clinical symptoms and signs. We describe an unusual case of PRES with isolated pontine involvement with coincidental acute ischaemic stroke in a 60-year-old man who presented with headache, unsteadiness of gait, blurred vision and elevated blood pressure. MRI scan revealed an expanded pons with diffuse T2 and Fluid attenuated Inversion Recovery (FLAIR) hyperintensities and an acute infarct in the right temporal lobe. Read More

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http://dx.doi.org/10.1136/bcr-2018-227132DOI Listing
April 2019
1 Read

Amphetamine and Clonidine Toxicity Resulting in Posterior Reversible Encephalopathy Syndrome.

Pediatr Emerg Care 2019 Apr 9. Epub 2019 Apr 9.

Emergency Medicine, and.

Amphetamine toxicity typically presents with hypertension and tachycardia. Conversely, clonidine acts as an agonist at central α2 and imidazoline receptors, which may cause brief initial hypertension followed by hypotension and bradycardia in overdose. We report a case of mixed ingestion resulting in posterior reversible encephalopathy syndrome (PRES) successfully treated with phentolamine. Read More

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http://dx.doi.org/10.1097/PEC.0000000000001819DOI Listing
April 2019
3 Reads

Orexin Receptor-1 in the Rostral Ventrolateral Medulla Mediates the Antihypertensive Effects of Electroacupuncture.

Front Neurosci 2019 26;13:282. Epub 2019 Mar 26.

Shaanxi Key Laboratory of Chinese Medicine Encephalopathy, Shaanxi University of Chinese Medicine, Xianyang, China.

Electroacupuncture (EA) has been used to treat numerous diseases, including hypertension. This study aimed to investigate the long-term effect and underlying mechanisms of EA stimulation at the LI11 point on the hypertension and sympathetic nerve activity in two-kidney, one-clip (2K1C) hypertensive rats. EA (0. Read More

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http://dx.doi.org/10.3389/fnins.2019.00282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443850PMC
March 2019
1 Read

Arginine Vasopressin and Posterior Reversible Encephalopathy Syndrome Pathophysiology: the Missing Link?

Mol Neurobiol 2019 Mar 28. Epub 2019 Mar 28.

Université de Tours, INSERM, Centre d'étude des pathologies respiratoires (CEPR) - UMR 1100, CHRU de Tours, Service de Médecine Intensive Réanimation, CIC 1415, réseau CRICS-TRIGGERSEP, Tours, France.

Posterior reversible encephalopathy syndrome (PRES) is a clinicoradiological entity characterized by a typical brain edema. Its pathogenesis is still debated through hypoperfusion and hyperperfusion theories, which have many limitations. As PRES occurs almost exclusively in clinical situations with arginine vasopressin (AVP) hypersecretion, such as eclampsia and sepsis, we hypothesize that AVP plays a central pathophysiologic role. Read More

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http://dx.doi.org/10.1007/s12035-019-1553-yDOI Listing
March 2019
4 Reads

Posterior reversible encephalopathy syndrome with isolated infratentorial involvement: A case report.

Radiol Case Rep 2019 May 1;14(5):576-580. Epub 2019 Mar 1.

Neurology Department, University of Minnesota, Minneapolis, MN, USA.

Posterior reversible encephalopathy syndrome (PRES) is a clinical and radiological entity of acute neurological symptoms associated with characteristic MRI finding. Vasogenic edema in the white matter of parieto-occipital regions is the classical MRI findings. Spinal cord involvement in PRES is extremely rare and frequently underrecognized condition. Read More

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http://dx.doi.org/10.1016/j.radcr.2019.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402429PMC
May 2019
1 Read

End-stage renal disease secondary to anti-glomerular basement membrane disease in a child with common variable immunodeficiency.

Clin Nephrol Case Stud 2019 1;7:1-6. Epub 2019 Feb 1.

Division of Pediatric Nephrology, Department of Pediatrics.

Background: Anti-glomerular basement membrane (GBM) disease is caused by autoantibodies against the α3-chain of type IV collagen in the GBM. Common variable immunodeficiency (CVID) is a primary immunodeficiency manifested by hypogammaglobulinemia, inability to make functional antibody, and recurrent infections. This report extends the phenotype of CVID-associated autoimmune diseases to include anti-GBM disease. Read More

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http://dx.doi.org/10.5414/CNCS109510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374989PMC
February 2019
2 Reads

Establishment and utility assessment of posterior reversible encephalopathy syndrome early warning scoring (PEWS) scale establishment and utility assessment of PEWS scale.

BMC Neurol 2019 Feb 21;19(1):30. Epub 2019 Feb 21.

Department of Pediatrics, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China.

Background: Posterior reversible encephalopathy syndrome (PRES) is a complication that occurs during various diseases' treatment. Imaging examination is the gold standard for diagnosis. PRES frequently occurrence in patients with hematological malignancies results in poorer prognosis and higher mortality. Read More

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http://dx.doi.org/10.1186/s12883-019-1247-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385440PMC
February 2019
3 Reads

Hypertensive emergency presenting with acute spontaneous subdural hematoma.

J Cardiol Cases 2019 Jan 16;19(1):25-28. Epub 2018 Oct 16.

Cardiovascular Department at Mount Sinai Heart, New York, NY, USA.

Hypertensive crisis is a serious medical condition defined as severely elevated blood pressure; typically the systolic blood pressure is above 180 mmHg, and/or the diastolic blood pressure is above 120 mmHg. Hypertensive crises are divided into two categories: hypertensive urgency and hypertensive emergency. Hypertensive urgency is asymptomatic while hypertensive emergency presents with end-organ damage requiring more aggressive blood-pressure lowering. Read More

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http://dx.doi.org/10.1016/j.jccase.2018.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342702PMC
January 2019
2 Reads

Posterior reversible encephalopathy syndrome with spinal cord involvement but without hemisphere lesions: A case report.

Medicine (Baltimore) 2019 Jan;98(2):e13649

Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.

Rationale: Posterior reversible encephalopathy syndrome (PRES) was termed by Hinchey in 1996. Patients have a reversible vasogenic brain edema in imaging and acute neurological symptoms such as headache, seizures, encephalopathy, and visual disturbances when suffering from hypertension, pre-eclampsia/eclampsia, renal failure, immunosuppressive medications, autoimmune disorders, sepsis, thrombocytopaenia, hypocalcaemia, alcohol withdrawal, and many other potential causes. de Havenon A et al have proposed a new syndrome named PRES with spinal cord involvement (PRES-SCI). Read More

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http://dx.doi.org/10.1097/MD.0000000000013649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336622PMC
January 2019
4 Reads

Comparison of transjugular intrahepatic portosystemic shunt for treatment of variceal bleeding in patients with cirrhosis with or without spontaneous portosystemic shunt.

Eur J Gastroenterol Hepatol 2019 Jan 9. Epub 2019 Jan 9.

Department of Gastroenterology, Nanjing Medical University Drum Tower Clinical Medical School.

Background And Aims: Transjugular intrahepatic portosystemic shunt (TIPS) is an effective intervention for portal hypertensive complications in cirrhosis. Spontaneous portosystemic shunts (SPSSs) may increase the risk of post-TIPS complications and mortality. This study was done to evaluate the safety and efficacy of TIPS for treating variceal bleeding between patients with and without SPSSs. Read More

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http://dx.doi.org/10.1097/MEG.0000000000001349DOI Listing
January 2019
12 Reads

[Posterior reversible encephalopathy syndrome in systemic lupus erythematosus: a case report].

Beijing Da Xue Xue Bao Yi Xue Ban 2018 Dec;50(6):1102-1107

Department of Rheumatology and Immunology, Peking University First Hospital, Beijing 100034, China.

This case report concerns a 22-year-old woman who had been diagnosed with systemic lupus erythematosus (SLE). She had intermittent fever, butterfly erythema, photosensitivity, oral ulcers, and multiple arthralgia in the past seven years, but she did not adhere to regular treatments. The edema of the lower extremities and face aggravated in the recent two weeks, so she was admitted to our Department of Rheumatology and Clinical Immunology. Read More

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December 2018
3 Reads

Immunosuppression-associated posterior reversible encephalopathy syndrome in an acute leukemia case.

Hematol Rep 2018 Nov 6;10(4):7257. Epub 2018 Nov 6.

Department of Hematology, Hacettepe University School of Medicine, Ankara, Turkey.

Posterior reversible encephalopathy syndrome (PRES) was described in 1996. Herein, we aimed to report an immunosuppression- related PRES case. A 34-year-old woman was diagnosed as t-cell acute lymphoblastic leukemia and allogeneic hematopoietic stem cell transplantation (HSCT) was performed. Read More

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http://dx.doi.org/10.4081/hr.2018.7257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240836PMC
November 2018

Headache in Pregnancy, the Puerperium, and menopause.

Semin Neurol 2018 12 6;38(6):627-633. Epub 2018 Dec 6.

Department of Neurology, University at Buffalo School of Medicine and Biomedical Sciences, The State University of New York, Buffalo, New York.

Headache is a neurologic disorder that displays gender dichotomy. It is well established that there is a strong link between migraine headache and sex hormones, specifically estrogen, which influences the severity of migraines during the menstrual cycle, pregnancy, and menopause. Furthermore, the epidemiology of headaches during pregnancy and the postpartum period is very distinct from that in males or nonpregnant females, in part due to the hemodynamic and hematologic changes that occur during pregnancy. Read More

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http://dx.doi.org/10.1055/s-0038-1673681DOI Listing
December 2018
24 Reads

Influential factors and clinical significance of an atypical presentation of posterior reversible encephalopathy syndrome in patients with eclampsia.

Neurol Sci 2019 Feb 26;40(2):377-384. Epub 2018 Nov 26.

Department of Neurology, Shengjing Hospital of China Medical University, 36 Sanhao Street, Heping District, Shenyang, 110004, Liaoning, People's Republic of China.

Background And Purpose: Posterior reversible encephalopathy syndrome (PRES) is a clinical and radiologic entity for which eclampsia is one of the most common predisposing conditions. Despite the imaging changes typically reported, the predisposing factors and clinical implications of atypical presentations have yet to be fully clarified.

Methods: A total of 56 patients with PRES were selected for study. Read More

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http://dx.doi.org/10.1007/s10072-018-3642-5DOI Listing
February 2019
1 Read

Stroke in Pregnancy: An Update.

Neurol Clin 2019 Feb;37(1):131-148

Department of Neurology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, WACC 729-C, Boston, MA 02114, USA. Electronic address:

Pregnancy confers a substantially increased risk of stroke in women. The period of highest risk of stroke is the peripartum/postpartum phase, coinciding with the highest risk for hypertensive disorders of pregnancy and peak gestational hypercoagulability. Hemorrhagic stroke is the most common type of obstetric stroke. Read More

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http://dx.doi.org/10.1016/j.ncl.2018.09.010DOI Listing
February 2019
23 Reads

Posterior reversible encephalopathy syndrome with extensive cytotoxic edema after blood transfusion: a case report and literature review.

BMC Neurol 2018 Nov 12;18(1):190. Epub 2018 Nov 12.

Division of Neurology, Department of Internal Medicine IV, Osaka Medical College, 2-7 Daigakumachi, Takatsuki, Osaka, 569-8686, Japan.

Background: Posterior reversible encephalopathy syndrome (PRES) is described as a clinical-radiological disease entity with good prognosis. In brain MRI, PRES generally presents with vasogenic edema. Although PRES is induced by various causes, a small number of PRES cases have occurred after red cell blood transfusion. Read More

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http://dx.doi.org/10.1186/s12883-018-1194-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231260PMC
November 2018
4 Reads

Posterior reversible encephalopathy syndrome complicated with subarachnoid hemorrhage in an eclamptic pregnant patient: case report.

BMC Neurol 2018 Nov 3;18(1):182. Epub 2018 Nov 3.

Department of Neurology, Renmin Hospital of Wuhan University, Jiefang Road 238, Wuchang District, Wuhan, 430060, China.

Background: Posterior reversible encephalopathy syndrome (PRES) is a neurotoxic condition which comprises various neurological symptoms. This syndrome could be complicated by intracranial hemorrhage including subarachnoid hemorrhage (SAH). However, SAH is rarely seen in eclamptic patients with PRES. Read More

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https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-
Publisher Site
http://dx.doi.org/10.1186/s12883-018-1186-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215355PMC
November 2018
14 Reads

Icariin ameliorates angiotensin II-induced cerebrovascular remodeling by inhibiting Nox2-containing NADPH oxidase activation.

Hum Cell 2019 Jan 1;32(1):22-30. Epub 2018 Nov 1.

Department of Encephalopathy, Hubei Provincial Traditional Chinese Medicine Hospital, Wuhan, People's Republic of China.

Cerebrovascular smooth muscle cells (SMCs) hyperplasia is an important contributor to cerebrovascular remodeling during hypertension. The aim of present study was to investigate the effects of Icariin on cerebrovascular SMCs proliferation and remodeling and the underlying mechanisms. The results revealed that Icariin administration attenuated the enhanced basilar artery constriction in angiotensin II (AngII)-induced hypertension rat model, as well as the inhibition of basilar artery diameter reduction in response to AngII and phenylephrine. Read More

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http://dx.doi.org/10.1007/s13577-018-0220-3DOI Listing
January 2019
6 Reads

Posterior reversible encephalopathy syndrome in association with exacerbation of chronic obstructive pulmonary disease: a case report.

BMC Neurol 2018 Oct 31;18(1):180. Epub 2018 Oct 31.

Department of Critical Care, Grande International Hospital (GIH), Kathmandu, Nepal.

Background: Posterior reversible encephalopathy syndrome (PRES) is a reversible clinical and neurological entity. There are varieties of comorbid conditions which are associated with PRES. Chronic obstructive pulmonary disease (COPD) is a rare predisposing factor for the development of PRES. Read More

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http://dx.doi.org/10.1186/s12883-018-1188-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208046PMC
October 2018
3 Reads

A man in his 50s with neurological symptoms during cancer treatment.

Tidsskr Nor Laegeforen 2018 10 23;138(17). Epub 2018 Oct 23.

Posterior reversible encephalopathy syndrome (PRES) is a rare clinicoradiographic disorder characterized by acute neurological symptoms with typical neuroimaging findings of vasogenic edema in posterior regions of the brain. This complication is linked to a number of medical conditions, and is increasingly being documented as a side effect associated with a number of therapeutic agents. We present a case of PRES as a result of treatment with the vascular endothelial growth factor (VEGF) multikinase inhibitor, regorafenib. Read More

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http://dx.doi.org/10.4045/tidsskr.18.0096DOI Listing
October 2018
1 Read

Electroacupuncture Improves Baroreflex and -Aminobutyric Acid Type B Receptor-Mediated Responses in the Nucleus Tractus Solitarii of Hypertensive Rats.

Neural Plast 2018 30;2018:8919347. Epub 2018 Sep 30.

Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, Research Center of Stomatology, Xi'an Jiaotong University College of Stomatology, Xi'an, Shaanxi 710004, China.

Electroacupuncture (EA) has been reported to benefit hypertension, but the underlying mechanisms are still unclear. We hypothesized that EA attenuates hypertension, in part, through modulation of -aminobutyric acid (GABA) receptor function in the nucleus tractus solitarii (NTS). In the present study, the long-term effect of EA on GABA receptor function and expression was examined in the NTS of two-kidney, one-clip (2K1C) renovascular hypertensive rats. Read More

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https://www.hindawi.com/journals/np/2018/8919347/
Publisher Site
http://dx.doi.org/10.1155/2018/8919347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186317PMC
January 2019
13 Reads

Posterior Reversible Encephalopathy Syndrome With Isolated Involving Infratentorial Structures.

Front Neurol 2018 9;9:843. Epub 2018 Oct 9.

Department of neurology, Renmin Hospital of Wuhan University, Wuhan, China.

Typical neuroimaging findings of posterior reversible encephalopathy syndrome include symmetrical white matter edema in subcortical white matter of bilateral occipital and parietal lobes, although variations do occur and more and more attention is being focused upon disease of infratentorial-isolated involved posterior reversible encephalopathy syndrome. In this article, we described 1 case of posterior reversible encephalopathy syndrome with isolated infratentorial brain involvement and reviewed the literature to identify an additional 36 cases in the PubMed database. We used various search terms, such as "brainstem/cerebella/spinal posterior reversible encephalopathy syndrome," "brainstem/cerebella/spinal reversible posterior leukoencephalopathy syndrome," "brainstem/cerebella/spinal hypertensive encephalopathy," "infratentorial posterior reversible encephalopathy syndrome," and "posterior reversible encephalopathy syndrome variant. Read More

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https://www.frontiersin.org/article/10.3389/fneur.2018.00843
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http://dx.doi.org/10.3389/fneur.2018.00843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189285PMC
October 2018
21 Reads

Baroreflex functionality in the eye of diffusion tensor imaging.

J Physiol 2019 Jan 2;597(1):41-55. Epub 2018 Nov 2.

Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, Republic of China.

By applying diffusion tensor imaging (DTI) as a physiological tool to evaluate changes in functional connectivity between key brainstem nuclei in the baroreflex neural circuits of mice and rats, recent work has revealed several hitherto unidentified phenomena regarding baroreflex functionality. (1) The presence of robust functional connectivity between nucleus tractus solitarii (NTS) and nucleus ambiguus (NA) or rostral ventrolateral medulla (RVLM) offers a holistic view on the moment-to-moment modus operandi of the cardiac vagal baroreflex or baroreflex-mediated sympathetic vasomotor tone. (2) Under pathophysiological conditions (e. Read More

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http://dx.doi.org/10.1113/JP277008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312450PMC
January 2019
14 Reads

Coma, Seizures, Atrioventricular Block, and Hypoglycemia in an ADB-FUBINACA Body-Packer.

J Emerg Med 2018 Dec 5;55(6):788-791. Epub 2018 Oct 5.

Department of Emergency Medicine, University of Rochester Medical Center, Rochester, New York; Upstate Poison Center, Syracuse, New York.

Background: Synthetic cannabinoid intoxication has become difficult to diagnose and manage in the United States, in part due to varying clinical effects within this heterogeneous group of compounds.

Case Report: A 38-year-old man was admitted with altered mental status and bradycardia. He demonstrated progressive encephalopathy, seizure activity, second-degree atrioventricular block type I, respiratory failure, hypotension, hypothermia, and hypoglycemia. Read More

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http://dx.doi.org/10.1016/j.jemermed.2018.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289710PMC
December 2018
13 Reads

Fludarabine-Induced Posterior Reversible Encephalopathy Syndrome in a Pediatric Patient With β-Thalassemia: Case Report and Literature Review.

Clin Neuropharmacol 2018 Nov/Dec;41(6):224-229

Pediatric Neurology Unit, Fundación Hospital Pediátrico La Misericordia, Bogotá, Colombia.

Posterior reversible encephalopathy syndrome is a disorder of reversible subcortical vasogenic brain edema in the context of different diseases or exposure to cytotoxic drugs such as fludarabine. We present the case of a pediatric patient with β-thalassemia who develops a fludarabine-induced posterior reversible encephalopathy while he received an induction regimen to achieve an allogenic hematopoietic cell transplantation. The clinical presentation consists in altered mental state, headache, status epilepticus, visual disturbance, and hypertension. Read More

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http://dx.doi.org/10.1097/WNF.0000000000000309DOI Listing
December 2018
3 Reads

Unusual Delayed Presentation of Posterior Reversible Encephalopathy Syndrome Following Vestibular Schwannoma Surgery: A Rare Neurologic Emergency.

World Neurosurg 2018 Dec 24;120:532-536. Epub 2018 Sep 24.

Department of Neurosurgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.

Background: Posterior reversible encephalopathy syndrome (PRES) is a rare neurologic condition that manifests with heterogeneous clinical findings, including altered mental status, seizure, vision loss, and vomiting. It characteristically leads to diffuse subcortical vasogenic edema, most commonly in the parieto-occipital regions. Although frequently reported with conditions such as hypertension, eclampsia, sepsis, electrolyte imbalances, autoimmune diseases, and immunosuppressive therapy, PRES may rarely occur after surgery for posterior fossa tumors. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183213
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http://dx.doi.org/10.1016/j.wneu.2018.09.084DOI Listing
December 2018
6 Reads
2.420 Impact Factor

[Non-drug therapy of vertigo].

Zh Nevrol Psikhiatr Im S S Korsakova 2018;118(8):38-42

Sechenov First Moscow State Medical University, Moscow, Russia.

Aim: To study the efficacy of various methods of non-drug therapy of diseases manifested by vertigo and dizziness in neurological practice.

Material And Methods: Referral and final diagnoses were compared after neurovestibular examination of 599 patients (177 men and 422 women), aged 25 to 79 years (mean age 55 years), with various causes of vertigo. Patients underwent vestibular rehabilitation, trainings on the stabiloplatform with biological feedback (biofeedback), repositioning maneuvers in patients with benign paroxysmal positional vertigo (BPPV). Read More

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http://dx.doi.org/10.17116/jnevro201811808138DOI Listing
March 2019
6 Reads

Posterior reversible encephalopathy syndrome in eclampsia.

Neurol India 2018 Sep-Oct;66(5):1316-1323

Department of Neurology, King George's Medical University, Lucknow, Uttar Pradesh, India.

Posterior reversible encephalopathy syndrome is characterized by acute headache, visual impairment, seizures, and altered mental status; neuroimaging may show cerebral edema affecting the parietal and occipital lobes of the brain. The objective of this article is to review the current understanding of posterior reversible encephalopathy syndrome in eclampsia. Literature was searched from PubMed, Scopus, and Google Scholar databases. Read More

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http://dx.doi.org/10.4103/0028-3886.241364DOI Listing
September 2018
4 Reads

Doppler ultrasound surveillance of TIPS-patency in the era of covered stents - retrospective analysis of a large single-center cohort.

Z Gastroenterol 2018 09 17;56(9):1053-1062. Epub 2018 Sep 17.

Medizinische Klinik I, Klinikum Ludwigsburg, Germany.

Purpose: The purpose of this study was to determine accuracy and necessity of long-term Doppler ultrasound (DU) surveillance of transjugular intrahepatic portosystemic shunt (TIPS) patency after implantation of an ePTFE-covered stent-graft (Viatorr).

Methods: This single-center retrospective study includes 228 consecutive cirrhotic patients with TIPS implantation due to portal hypertensive complications. Standardized DU surveillance was scheduled 3 - 5 days, 3 months, and 6 months after TIPS implantation and every 6 months thereafter. Read More

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http://dx.doi.org/10.1055/s-0044-102107DOI Listing
September 2018
6 Reads

Acute intermittent porphyria presenting with seizures and posterior reversible encephalopathy syndrome: Two case reports and a literature review.

Medicine (Baltimore) 2018 Sep;97(36):e11665

Urology Department, Qilu Hospital of Shandong University, Qingdao, Shandong Province, China.

Introduction: Acute intermittent porphyria (AIP) is a rare and challenging hereditary neurovisceral disease with no specific symptoms. Posterior reversible encephalopathy syndrome (PRES) is a clinicoradiological syndrome with bilateral reversible posterior gyriform lesions that can be associated with many different conditions, including AIP. Usually, peripheral neuropathy is considered the most common neurological manifestation of AIP. Read More

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http://dx.doi.org/10.1097/MD.0000000000011665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133578PMC
September 2018
15 Reads

[Mycophenolate mofetil versus cyclosporine A in children with primary refractory nephrotic syndrome].

Zhonghua Er Ke Za Zhi 2018 Sep;56(9):651-656

Department of Pediatrics, Beijing Tsinghua Changgung Hospital, Tsinghua University, Beijing102218, China Geng Haiyun and Ji Lina contributed equally to this article.

To compare the efficacy and safety of mycophenolate mofetil versus cyclosporine A in treating children with primary refractory nephrotic syndrome. Conducted a prospective randomized controlled clinical trial in 62 pediatric patients (including 44 boys and 18 girls), age ranged from 2.1 to 17. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0578-1310.2018.09.004DOI Listing
September 2018
28 Reads

Neonatal Morbidity in the Offspring of Obese Women Without Hypertension or Diabetes.

Obstet Gynecol 2018 Oct;132(4):835-841

Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri.

Objective: To compare the independent risk of neonatal morbidity between the offspring of obese and nonobese women without hypertension or diabetes.

Methods: This is a secondary analysis of a prospective single-center cohort study of singleton deliveries at or beyond 37 weeks of gestation from 2010 to 2014. Women with diabetes (pregestational or gestational) and hypertensive disorders were excluded. Read More

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http://dx.doi.org/10.1097/AOG.0000000000002775DOI Listing
October 2018
3 Reads

[Clinical characteristics analysis of children with reversible posterior leukoen-cephalopathy syndrome during the treatment of hematological tumor].

Beijing Da Xue Xue Bao Yi Xue Ban 2018 Aug;50(4):662-665

Department of Pediatrics, Peking University First Hospital, Beijing 100034, China.

Objective: To analyze the clinical characteristics of patients with hematological tumor or disease before and after reversible posterior leukoen-cephalopathy syndrome (RPLS).

Methods: Five patients were both from Peking University First Hospital Pediatric Hematology-oncology Department in the period from March 2012 to March 2017. The gender, age, BMI, underlying diseases, with or without renal damage, hypertension family history, clinical manifestations of convulsions, hemoglobin, and blood pressure, serum sodium levels before and after convulsion, and other data of the children with RPLS were retrospectively analyzed. Read More

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August 2018
15 Reads

Mineralocorticoid Receptors, Neuroinflammation and Hypertensive Encephalopathy.

Cell Mol Neurobiol 2019 May 16;39(4):483-492. Epub 2018 Aug 16.

Laboratory of Neuroendocrine Biochemistry, Instituto de Biologia y Medicina Experimental-CONICET, Buenos Aires, Argentina.

Worldwide, raised blood pressure is estimated to affect 35-40% of the adult population and is a main conditioning factor for cardiovascular diseases and stroke. Animal models of hypertension have provided great advances concerning the pathophysiology of human hypertension, as already shown for the deoxycorticosterone-salt treated rat, the Dahl-salt sensitive rat, the Zucker obese rat and the spontaneously hypertensive rat (SHR). SHR has been widely used to study abnormalities of the brain in chronic hypertension. Read More

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http://dx.doi.org/10.1007/s10571-018-0610-9DOI Listing
May 2019
3 Reads

Congenital adrenal hyperplasia due to 17-alpha hydroxylase deficiency with hypertensive encephalopathy, hypoglycemic seizures and adrenal insufficiency.

Authors:
Narendra Kumar

J Anaesthesiol Clin Pharmacol 2018 Apr-Jun;34(2):261-262

Department of Anaesthesia and Intensive Care, Narayana Nethralaya, Bengaluru, Karnataka, India.

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http://dx.doi.org/10.4103/0970-9185.173401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066868PMC
August 2018
3 Reads

Paradoxical hypertension.

Oxf Med Case Reports 2018 Jul 25;2018(7):omy037. Epub 2018 Jul 25.

Dr. B.R. Ambedkar Medical College, Bangalore, India.

Posterior reversible encephalopathy syndrome (PRES) is a clinico-radiological syndrome characterized by white matter vasogenic edema affecting the posterior occipital and parietal lobes of the brain predominantly. A 48-year-old female patient presented to ER with complaints of breathlessness and developed sudden painless loss of vision while eliciting history. The patient had a heart rate of 104/min and accelerated hypertension (BP of 220/120 mm of Hg). Read More

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http://dx.doi.org/10.1093/omcr/omy037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059163PMC
July 2018
4 Reads

Posterior Reversible Encephalopathy Syndrome and Guillain-Barré Syndrome after Head Injury: Case Report.

Neurol Med Chir (Tokyo) 2018 Oct 3;58(10):453-458. Epub 2018 Aug 3.

Department of Neurosurgery, Tochigi Medical Center Shimotsuga.

We report a case of head injury with posterior reversible encephalopathy syndrome (PRES), followed by Guillain-Barré syndrome (GBS). A 74-year-old man was brought to our hospital after a fall. Computed tomography revealed intracranial hemorrhage. Read More

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https://www.jstage.jst.go.jp/article/nmc/58/10/58_cr.2018-00
Publisher Site
http://dx.doi.org/10.2176/nmc.cr.2018-0049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186763PMC
October 2018
13 Reads

Trastuzumab-associated Posterior Reversible Encephalopathy Syndrome.

Cureus 2018 May 24;10(5):e2686. Epub 2018 May 24.

Hematology and Oncology, University of Missouri Kansas City School of Medicine, Kansas City, USA.

Posterior reversible encephalopathy syndrome (PRES) is a clinical-radiographic syndrome that presents with neurological manifestations, including seizures, headache, or confusion, and is associated with posterior cerebral white matter edema on imaging. PRES is typically a benign and reversible condition. However, PRES can be fatal or associated with permanent deficits. Read More

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http://dx.doi.org/10.7759/cureus.2686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059531PMC
May 2018
5 Reads

Posterior Reversible Encephalopathy Syndrome after Augmentation Cystoplasty in a Child with Neurogenic Bladder.

J Indian Assoc Pediatr Surg 2018 Jul-Sep;23(3):158-160

Department of Pediatric Surgery, SKIMS, Srinagar, Jammu and Kashmir, India.

Posterior reversible encephalopathy syndrome (PRES) or leukoencephalopathy syndrome was introduced into clinical practice in 1996 by Hinchey ., to describe unique syndrome, clinically expressed during hypertensive and uremic encephalopathy, eclampsia, and immunosuppressive therapy. Hyperperfusion with resultant disruption of the blood-brain barrier results in vasogenic edema, but not infarction, most commonly in the parieto-occipital regions. Read More

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http://dx.doi.org/10.4103/jiaps.JIAPS_204_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042172PMC
July 2018
4 Reads

First case of neurofibromatosis with posterior reversible encephalopathy syndrome showing spinal cord involvement.

Indian J Radiol Imaging 2018 Apr-Jun;28(2):161-164

Department of Radiology and Imaging, Queen Elizabeth Hospital, Kowloon, Hong Kong (SAR), People's Republic of China.

Posterior reversible encephalopathy syndrome (PRES) is a well-documented pathology of the brain in systemic upsets. Majority of PRES cases present with edema in the cerebrum, most commonly in the territory of posterior circulation. It has been reported to show spinal cord involvement in a rare subgroup known as PRES with spinal cord involvement (PRES-SCI), with very limited existing literature even in adult patients. Read More

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http://dx.doi.org/10.4103/ijri.IJRI_320_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038224PMC
July 2018
3 Reads

Posterior Reversible Encephalopathy Syndrome: A Case of Hypercalcemia.

Acta Med Port 2018 Jun 29;31(6):338-340. Epub 2018 Jun 29.

Serviço de Medicina 2. Centro Hospitalar de Leria. Leiria, Portugal.

Posterior reversible encephalopathy syndrome is an encephalopathy that can be clinically characterized by headache, altered mental status and/or seizures. Neuroimaging demonstrates usually reversible bilateral subcortical vasogenic occipital-parietal edema. Exact pathophysiology remains unclear but is commonly associated with hypertension, renal failure, sepsis and use of immunosuppressive therapy. Read More

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http://dx.doi.org/10.20344/amp.9714DOI Listing
June 2018
3 Reads

A Late Complication Occurring Due to Tacrolimus After Liver Transplant: Posterior Reversible Encephalopathy Syndrome.

Exp Clin Transplant 2018 Jul 11. Epub 2018 Jul 11.

From the General Surgery Department, Fırat University Medicine School, Elazığ, Turkey.

Posterior reversible encephalopathy syndrome is a rare condition of the central nervous system that may occur in adults as well as in children. Clinically, it presents with mental status changes, visual loss, headaches, seizures, or coma. The diagnosis of posterior reversible encephalopathy syndrome is based on the typical appearance in occipital and parietal lobes in radiologic imaging studies, such as computed tomography or magnetic resonance imaging of the brain, which exhibit the typical appearance due to vasogenic edema. Read More

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http://dx.doi.org/10.6002/ect.2017.0248DOI Listing
July 2018
9 Reads

A case of posterior reversible encephalopathy syndrome associated with sepsis.

BMJ Case Rep 2018 Jul 10;2018. Epub 2018 Jul 10.

Department of Internal Medicine, Texas Tech University Health Science Center at Permian Basin, Odessa, Texas, USA.

Posterior reversible encephalopathy syndrome (PRES) is a neurological disorder characterised by parieto-occipital vasogenic oedema seen on MRI. Infection and sepsis has been reported as a possible cause for this disorder.We present a 19-year-old immunocompetent Caucasian man with known type 1 diabetes mellitus who presented to the emergency department with acute onset of bilateral visual loss, headaches and hypertension; he had been discharged 2 weeks ago for severe diabetic ketoacidosis and bacteraemia. Read More

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http://dx.doi.org/10.1136/bcr-2018-225128DOI Listing
July 2018
13 Reads

Symptomatic Lacunar Infarct Accompanied with Posterior Reversible Encephalopathy Syndrome: A Case Report.

Tokai J Exp Clin Med 2018 Jul 20;43(2):64-67. Epub 2018 Jul 20.

Division of Neurology, Department of Internal Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan.

We present a 48-year-old man with a history of hypertension, who suddenly noticed dysarthria and right hemiparesis. Diffusion-weighted MRI at 1 day after the onset showed a small high-intensity region in the left corona radiata, indicating the acute phase of lacunar infarction. Fluid attenuation inversion recovery images showed extensive hyperintense lesions predominantly in the white matter of the fronto-temporoparietal lobes and pons, indicating posterior reversible encephalopathy syndrome (PRES). Read More

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July 2018
2 Reads

Understanding posterior reversible encephalopathy syndrome.

JAAPA 2018 Jul;31(7):31-34

Kenneth Fittro and Roderick Dizon practice at Borgess Medical Center in Kalamazoo, Mich. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Posterior reversible encephalopathy syndrome is a characteristic clinical-radiographic syndrome with diverse and multifactorial causes. Symptoms include headache, altered mental status, seizures, nausea and vomiting, and vision abnormalities. The syndrome is treated by lowering BP, administering anticonvulsant medications, correcting metabolic abnormalities, and removing offending agents. Read More

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http://dx.doi.org/10.1097/01.JAA.0000534980.69236.81DOI Listing
July 2018
2 Reads

Case 20-2018: A 64-Year-Old Man with Fever, Arthralgias, and Testicular Pain.

N Engl J Med 2018 Jun;378(26):2518-2529

From the Department of Medicine, Brigham and Women's Hospital (C.A.S.), the Departments of Medicine (C.A.S., Z.S.W.), Radiology (A.K.), and Pathology (K.G.), Massachusetts General Hospital, and the Departments of Medicine (C.A.S., Z.S.W.), Radiology (A.K.), and Pathology (K.G.), Harvard Medical School - all in Boston.

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http://dx.doi.org/10.1056/NEJMcpc1800334DOI Listing
June 2018
35 Reads

Balloon-Occluded Retrograde Transvenous Obliteration versus Transjugular Intrahepatic Portosystemic Shunt for the Management of Gastric Variceal Bleeding.

Gut Liver 2018 11;12(6):704-713

Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea.

Background/aims: Gastric varices (GVs) are a major cause of upper gastrointestinal bleeding in patients with liver cirrhosis. The current treatments of choice are balloon-occluded retrograde transvenous obliteration (BRTO) and the placement of a transjugular intrahepatic portosystemic shunt (TIPS). We aimed to compare the efficacy and outcomes of these two methods for the management of GV bleeding. Read More

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http://www.gutnliver.org/journal/view.html?doi=10.5009/gnl17
Publisher Site
http://dx.doi.org/10.5009/gnl17515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254622PMC
November 2018
15 Reads

Posterior reversible encephalopathy syndrome (PRES) after bevacizumab therapy for metastatic colorectal cancer.

J Community Hosp Intern Med Perspect 2018 12;8(3):130-133. Epub 2018 Jun 12.

Division of Hematology/Oncology, University of Maryland Medical Center, Baltimore, MD, USA.

Posterior reversible encephalopathy syndrome (PRES) is an increasingly recognizable neuro-clinical syndrome. Clinical and neurological manifestations of PRES include hypertension, headache, encephalopathy, seizures, and symmetrical white matter changes on brain MRI. Most common precipitants of PRES are acute medical illness, hypertensive crisis, eclampsia, immunosuppressive therapy, and chemotherapy. Read More

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http://dx.doi.org/10.1080/20009666.2018.1478563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998282PMC
June 2018
3 Reads

Multiple subcutaneous metastases as the solitary presenting site of colorectal cancer.

J Cancer Res Ther 2018 Apr-Jun;14(3):716-718

Department of Radiotherapy, Regional Institute of Medical Sciences, Imphal, Manipur, India.

Skin metastases, as a presenting symptom of gastrointestinal malignancies, are very rare and signify aggressive disease. They usually occur after a long period of diagnosis and along with other visceral metastases. We present the case of an 18-year-old male with diffuse subcutaneous metastases as a presenting feature and as the only site of distant metastases due to rectosigmoid adenocarcinoma. Read More

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http://dx.doi.org/10.4103/0973-1482.172586DOI Listing
November 2018
2 Reads

Nocturnal Hypertension in Multiple System Atrophy May Cause Posterior Reversible Encephalopathy Syndrome.

Intern Med 2018 Nov 6;57(21):3187-3191. Epub 2018 Jun 6.

Department of Neurology, Tenri Hospital, Japan.

Nocturnal hypertension (NH) is a symptom of cardiovascular dysautonomia in multiple system atrophy (MSA); however, care and medication are often insufficient. We herein report a patient with MSA who showed posterior reversible encephalopathy syndrome (PRES) caused by hypertension during sleep. He presented clinically with total blindness; T2-weighted magnetic resonance imaging showed high signal intensities in the bilateral subcortical occipital-temporal lobes. Read More

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http://dx.doi.org/10.2169/internalmedicine.0759-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262696PMC
November 2018
2 Reads