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    2175 results match your criteria Encephalopathy Hypertensive

    1 OF 44

    Life-threatening posterior reversible encephalopathy syndrome in the cerebellum treated by posterior fossa decompression.
    Acta Neurochir (Wien) 2017 May 25. Epub 2017 May 25.
    Department of Neurosurgery, Heinrich Heine University Duesseldorf, Moorenstr. 5, 40225, Duesseldorf, Germany.
    Posterior reversible encephalopathy syndrome (PRES) is a clinico-neuroradiological syndrome associated with various clinical conditions, such as headache, encephalopathy, and seizures. It is reversible if a prompt diagnosis is made and treatment undertaken. We report a 52-year-old male with hypertensive crisis. Read More

    Mineralocorticoid receptor associates with pro-inflammatory bias in hippocampus of spontaneously hypertensive rats.
    J Neuroendocrinol 2017 May 18. Epub 2017 May 18.
    Laboratory of Neuroendocrine Biochemistry, Instituto de Biologia y Medicina Experimental-CONICET, Buenos Aires, Argentina.
    Damage observed in the hippocampus of the adult spontaneously hypertensive rat (SHR) resembles the neuropathology of mineralocorticoid-induced hypertension, supporting a similar endocrine dysfunction in both entities. In this study we have tested the hypothesis that increased expression of the hippocampal mineralocorticoid receptor (MR) in SHR animals is associated with a prevalent expression of pro-inflammatory over anti-inflammatory factors. For this purpose we measured in hippocampus mRNA expression and immunoreactivity of the MR and the glucocorticoid receptor (GR) using qPCR and histochemistry. Read More

    Posterior reversible encephalopathy syndrome presenting in the anterior circulation with malignant intracranial hypertension requiring surgical decompression: a case report and literature review.
    Acta Neurochir (Wien) 2017 May 17. Epub 2017 May 17.
    Department of Neurological Surgery, Universitätsmedizin Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany.
    Posterior reversible encephalopathy syndrome (PRES) is thought to result from endothelial dysfunction and breakdown of the blood-brain barrier with subsequent vasogenic edema. Abrupt hypertension has been identified as one of its risk factors. We present a rare case of PRES in the anterior circulation with sudden onset of left hemiparesis and rapid neurological deterioration on the basis of hypertensive crisis. Read More

    Venous hypertensive encephalopathy secondary to venous sinus thrombosis and dural arteriovenous fistula.
    Pract Neurol 2017 May 16. Epub 2017 May 16.
    Department of Neurology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
    A 52-year-old man with a history of factor V Leiden thrombophilia, persistent headaches and papilloedema presented with worsening vision and confusion. MRI and MR angiography of the brain at the time of this presentation showed findings concerning for transverse sinus thrombosis and an associated dural arteriovenous fistula. Dural venous sinus thrombosis can lead to the formation of a dural arteriovenous fistula, which must be considered in the differential diagnosis for intracranial hypertension in patients with thrombophilia. Read More

    Posterior reversible encephalopathy syndrome in a postpartum hemorrhagic woman without hypertension: A case report.
    Medicine (Baltimore) 2017 Apr;96(16):e6690
    aDepartment of Nuclear Medicine, Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan bCentro Hospitalar Conde de São Januário, Macao, China cDepartment of Medicine, National Defense Medical Center, Taipei City dDepartment of Emergency, E-Da Hospital, Kaohsiung City eSchool of Medicine, National Yang-Ming University, Taipei City, Taiwan.
    Rationale: Posterior reversible encephalopathy syndrome (PRES), which diagnosis is based on clinical symptoms and radiological features, is a neurotoxic disease characterized by a set of clinical manifestations, such as seizure, headache, visual, and/or consciousness disturbance. It is the first case of PRES followed by postpartum hemorrhage (PPH) without underlying disease.

    Patient Concerns: A 37-year-old healthy woman had PPH after caesarean section. Read More

    Rifampicin reverses nicardipine effect inducing uncontrolled essential hypertension.
    Fundam Clin Pharmacol 2017 Apr 13. Epub 2017 Apr 13.
    Department of Hypertension, Vascular Disease and Clinical Pharmacology, Strasbourg Regional University Hospital, France.
    Dihydropyridine calcium-channel blockers are a known substrate for the cytochrome P450 isoform 3A4. Rifampicin, an antitubercular agent, is one of the most potent inducers of hepatic and intestinal CYP3A4 thus increasing dihydropyridine metabolism. We report a case of a 67-year-old hypertensive female treated with a 4-drug antihypertensive regimen including a dihydropyridine (nicardipine 50mg bid), who was admitted for septic arthritis of the knee requiring antibiotic treatment with teicoplanin 400mg od and rifampicin 600mg bid. Read More

    Quantitative Magnetic Resonance Diffusion-Weighted Imaging Evaluation of the Supratentorial Brain Regions in Patients Diagnosed with Brainstem Variant of Posterior Reversible Encephalopathy Syndrome: A Preliminary Study.
    J Stroke Cerebrovasc Dis 2017 Mar 21. Epub 2017 Mar 21.
    Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan; Institute of Neuroscience, School of Life Science, National Yang-Ming University, Taipei, Taiwan.
    Background And Purpose: Posterior reversible encephalopathy syndrome (PRES) is a clinicoradiologic entity with several causes, characterized by rapid onset of symptoms and typical neuroimaging features, which usually resolve if promptly recognized and treated. Brainstem variant of PRES presents with vasogenic edema in brainstem regions on magnetic resonance (MR) images and there is sparing of the supratentorial regions. Because PRES is usually caused by a hypertensive crisis, which would likely have a systemic effect and global manifestations on the brain tissue, we thus proposed that some microscopic abnormalities of the supratentorial regions could be detected with diffusion-weighted imaging (DWI) using apparent diffusion coefficient (ADC) analysis in brainstem variant of PRES and hypothesized that "normal-looking" supratentorial regions will increase water diffusion. Read More

    Acute Intermittent Porphyria Presenting with Posterior Reversible Encephalopathy Syndrome, Accompanied by Prolonged Vasoconstriction.
    Intern Med 2017 17;56(6):713-717. Epub 2017 Mar 17.
    Department of Neurology, Kagawa University Hospital, Japan.
    A 20-year-old Japanese woman had an attack of acute intermittent porphyria (AIP). Magnetic resonance imaging (MRI) revealed symmetrical lesions in the cerebrum and cerebellar hemisphere, corresponding to posterior reversible encephalopathy syndrome (PRES). Our administration of heme arginate gradually improved the clinical condition associated with AIP and the level of metabolite of nitric oxide (NO), which is a vascular dilator. Read More

    Multidisciplinary Approach to Complicated Pregnancy.
    South Med J 2017 Mar;110(3):154-160
    From the Department of Pathophysiology, University of Split School of Medicine, Split, the Department of Internal Medicine, University Hospital Center Split, Split, University Psychiatric Hospital Vrapce, University of Zagreb School of Medicine, Zagreb, the Clinical Department of Diagnostic and Interventional Radiology University Hospital Center Split, Split, and the Department of Gynecology and Obstetrics, University Hospital Center Split, Split, Croatia.
    A nulliparous pregnant woman in her mid-20s and in the 32nd week of gestation presented to the emergency department with severe headache and vomiting. She had an uneventful medical history; however, the physical examination upon hospital admission revealed a hypertensive emergency, papilledema, and 2+ dipstick proteinuria. Upon establishing the diagnosis of preeclampsia, aggressive therapy with corticosteroids, antihypertensive medication, and seizure prophylaxis was initiated. Read More

    PRES and Epilepsy: A Potential Long-Term Consequence of a "Reversible" Syndrome.
    Neurologist 2017 Mar;22(2):41-43
    Departments of *Radiology ‡Neurology †College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR §Department of Neurology, Ohio State University, Columbus, OH.
    Epilepsy is very rarely attributed to posterior reversible encephalopathy syndrome (PRES). We report the case of a previously healthy 21-year-old who developed epilepsy with mesial temporal sclerosis following an episode of PRES related to a complicated Cesarean delivery. Neuroimaging at the time of PRES and 3 months after revealed the development of unilateral hippocampal volume loss following resolution of acute PRES-related brain edema. Read More

    Three cases of posterior reversible encephalopathy syndrome with chronic kidney disease triggered by infection.
    Nephrology (Carlton) 2017 Apr;22(4):322-325
    Division of Nephrology and Endocrinology, The University of Tokyo Hospital, Tokyo, Japan.
    Posterior reversible encephalopathy syndrome (PRES) is a clinical and radiological condition with diverse neurological manifestations. Many clinical factors are known causes of PRES, but only a few cases of PRES have been reported in patients with chronic kidney disease (CKD) and infectious disease. We describe three cases of PRES in patients with CKD triggered by various infectious diseases. Read More

    Should Posterior Reversible Encephalopathy Syndrome Be Mainly Considered an Epileptic Disorder? Results of a Sequential Neurophysiological Study in a Pediatric Cohort.
    Neuropediatrics 2017 Apr 28;48(2):72-78. Epub 2017 Feb 28.
    BMT Unit, Department of Pediatrics, MBBM Foundation, Monza, Italy.
    Despite a wide number of studies trying to define clinical, physiopathological, and neuroradiological features of posterior reversible encephalopathy syndrome (PRES), the true nature of symptoms is still not fully understood. We studied a standard cohort of 24 pediatric patients, affected by hemato-oncological diseases, with a neuroradiological diagnosis consistent with PRES identified from 2006 to 2013. Ten of them developed PRES after hematopoietic stem cell transplantation. Read More

    Various Imaging Manifestations of Posterior Reversible Encephalopathy Syndrome (PRES) on Magnetic Resonance Imaging (MRI).
    Pol J Radiol 2017 7;82:64-70. Epub 2017 Feb 7.
    Department of Radiodiagnosis, JSS Medical College and Hospital, JSS University, Mysore, India.
    Background: Posterior reversible encephalopathy syndrome (PRES), also called the acute hypertensive encephalopathy and reversible posterior leukoencephalopathy syndrome (RPLS), is a neurotoxic syndrome of cerebral vasoregulation classically characterized by bilaterally symmetrical parieto-occipital edema. However, the imaging findings are variable and may occur in other locations such as the frontal lobes, thalami, basal ganglia and brainstem. Most commonly, PRES presents with hyperintense signals on T2 and FLAIR sequences. Read More

    A case report of posterior reversible encephalopathy syndrome in a patient receiving gemcitabine and cisplatin.
    Medicine (Baltimore) 2017 Feb;96(8):e5850
    aDepartment of Internal Medicine, University of Alberta, Edmonton, Alberta bCross Cancer Institute, Edmonton, Alberta, Canada.
    Rationale: Posterior reversible encephalopathy syndrome (PRES) is a subacute syndrome causing characteristic neurologic and radiologic findings. PRES is predominantly caused by malignant hypertension though it has been associated with immunosuppressive treatments such as chemotherapy.

    Patient Concerns: We describe a case of a 58 year old female who developed fluctuant level of consciousness, agitation. Read More

    Towards developing criteria for scleroderma renal crisis: A scoping review.
    Autoimmun Rev 2017 Apr 14;16(4):407-415. Epub 2017 Feb 14.
    Faculty of Medicine, McGill University, Montreal, Quebec, Canada; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada; Department of Medicine, Division of Rheumatology, Jewish General Hospital, Montreal, Quebec, Canada.
    Objective: The absence of a gold standard for scleroderma renal crisis (SRC) has hindered our understanding of this problem. The objective of this scoping review was to identify the criteria used to define SRC in order to guide the development of a consensus definition for SRC.

    Methods: We conducted a search in three databases: Medline, Embase and non-Ovid Pubmed. Read More

    Posterior reversible encephalopathy in the intensive care unit.
    Handb Clin Neurol 2017 ;141:467-483
    Department of Neurology, Mayo Clinic, Rochester, MN, USA. Electronic address:
    Posterior reversible encephalopathy syndrome (PRES) is increasingly diagnosed in the emergency department, and medical and surgical intensive care units. PRES is characterized by acute onset of neurologic symptoms in the setting of blood pressure fluctuations, eclampsia, autoimmune disease, transplantation, renal failure, or exposure to immunosuppressive or cytotoxic drugs, triggers known to admit patients to the intensive care unit (ICU). Although the exact pathophysiology remains unknown, there is growing consensus that PRES results from endothelial dysfunction. Read More

    Inherited and Uncommon Causes of Stroke.
    Continuum (Minneap Minn) 2017 02;23(1, Cerebrovascular Disease):211-237
    Purpose Of Review: This article is a practical guide to identifying uncommon causes of stroke and offers guidance for evaluation and management, even when large controlled trials are lacking in these rarer forms of stroke.

    Recent Findings: Fabry disease causes early-onset stroke, particularly of the vertebrobasilar system; enzyme replacement therapy should be considered in affected patients. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), often misdiagnosed as multiple sclerosis, causes migraines, early-onset lacunar strokes, and dementia. Read More

    Clinical Characteristics of Transplant-associated Encephalopathy in Children.
    J Korean Med Sci 2017 Mar;32(3):457-464
    Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Korea.
    We aimed to analyze characteristics of encephalopathy after both hematopoietic stem cell and solid organ pediatric transplantation. We retrospectively reviewed medical records of 662 pediatric transplant recipients (201 with liver transplantation [LT], 55 with heart transplantation [HT], and 67 with kidney transplantation [KT], 339 with allogeneic hematopoietic stem cell transplantation [HSCT]) who received their graft organs at Asan Medical Center between January 2000 and July 2014. Of the 662 patients, 50 (7. Read More

    Basidiobolomycosis complicated by hydronephrosis and a perinephric abscess presenting as a hypertensive emergency in a 7-year-old boy.
    Paediatr Int Child Health 2017 Jan 23:1-4. Epub 2017 Jan 23.
    a Department of Pediatrics , Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) , Pondicherry 605006 , India.
    A 7-year-old boy presented with a chronic, indurated, tender left thigh swelling in association with a hypertensive emergency. He had a bilateral moderate degree of hydronephrosis and a left perinephric abscess, and MRI features of posterior reversible encephalopathy syndrome. Histopathological examination of the biopsy specimen demonstrated eosinophilic fasciitis with filamentous fungi. Read More

    Hyponatremic hypertensive syndrome - a retrospective cohort study.
    World J Nephrol 2017 Jan;6(1):41-44
    Devdeep Mukherjee, Rajiv Sinha, Md Shakil Akhtar, Department of Pediatric Medicine, Institute of Child Health, Kolkata 700017, India.
    Aim: To ascertain the frequency of hyponatremic hypertensive syndrome (HHS) in a cohort of children with hypertensive emergency in a tertiary pediatric hospital.

    Methods: A retrospective review was undertaken among children with hypertensive emergency admitted in our tertiary children hospital between June 2014 and December 2015 with an aim to identify any children with HHS. Three children with HHS were identified during this period. Read More

    Hypertensive disorders in pregnancy and later dementia: a Swedish National Register Study.
    Acta Obstet Gynecol Scand 2017 Apr 9;96(4):464-471. Epub 2017 Mar 9.
    Department of Pediatrics, Women and Infants Hospital, Warren Alpert Medical School of Brown University, Providence, RI, USA.
    Introduction: Our aim was to investigate the rate of vascular dementia and dementia in women with previous hypertensive disorders in pregnancy, since white matter lesions of the brain and cardiovascular disease are linked both to dementia and hypertensive disorders in pregnancy.

    Material And Methods: Prospective population-based registry study on all women giving birth in Sweden between 1973 and 1975 (284 598). Women with and without hypertensive disorders in pregnancy were identified by means of the Swedish Medical Birth Register and linked to the National Patient Register, where data on somatic disease later in life were obtained. Read More

    Evaluation of Helicobacter pylori Infection in Patients with Chronic Hepatic Disease.
    Chin Med J (Engl) 2017 01;130(2):149-154
    Department of Gastroenterology, the Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong 264000, China.
    Background: The 13C urea breath test (13C-UBT) is the gold standard for detecting Helicobacter pylori infection. H. pylori pathogenesis in patients with hepatitis B virus (HBV) and related diseases remains obscure. Read More

    Persistent fever investigation saves patient's life.
    J Fam Pract 2016 Nov;65(11):812-813
    Department of Family and Preventive Medicine, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AK, USA. Email:
    A 47-year-old woman had been hospitalized one month earlier for lupus nephritis with a hypertensive emergency that led to a seizure. During this earlier hospitalization, she was given a diagnosis of posterior reversible encephalopathy syndrome. Read More

    Posterior reversible encephalopathy syndrome.
    J Neurol 2017 Jan 4. Epub 2017 Jan 4.
    Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
    The posterior reversible encephalopathy syndrome (PRES) is a neurological disorder of (sub)acute onset characterized by varied neurological symptoms, which may include headache, impaired visual acuity or visual field deficits, disorders of consciousness, confusion, seizures, and focal neurological deficits. In a majority of patients the clinical presentation includes elevated arterial blood pressure up to hypertensive emergencies. Neuroimaging, in particular magnetic resonance imaging, frequently shows a distinctive parieto-occipital pattern with a symmetric distribution of changes reflecting vasogenic edema. Read More

    Reversible Hypertensive Myelopathy-The Spinal Cord Variant of Posterior Reversible Encephalopathy Syndrome.
    Neuropediatrics 2017 Apr 29;48(2):115-118. Epub 2016 Dec 29.
    Department of Pediatric Neurology, Hacettepe University, Ankara, Turkey.
    The posterior reversible encephalopathy syndrome (PRES) is a well-known clinical and radiologic entity mainly affecting the territory of the posterior cerebral circulation. Spinal cord involvement is extremely rare, and as of yet, only a few cases have been reported in the literature. The present case describes a reversible, longitudinal spinal cord lesion in a patient with high blood pressure. Read More

    Delayed onset of posterior reversible encephalopathy syndrome in a case of scleroderma renal crisis with maintenance hemodialysis: Case report and literature review.
    Medicine (Baltimore) 2016 Dec;95(52):e5725
    aDivision of Nephrology, Department of Internal Medicine, E-DA Hospital, No. 1, Yida Road, Jiaosu Village, Yanchao District, Kaohsiung City 82445, Taiwan, R.O.C bSchool of Medicine for International Students, I-Shou University, No. 8, Yida Rd., Jiaosu Village Yanchao District, Kaohsiung City 82445, Taiwan, R.O.C cDivision of Nephrology, Department of Internal Medicine, E-DA Cancer Hospital, No. 21, Yida Road, Jiaosu Village, Yanchao District, Kaohsiung City 82445, Taiwan, R.O.C.
    Introduction: In some cases, scleroderma renal crisis (SRC) is not easily distinguishable from other thrombotic microangiopathies such as thrombotic thrombocytopenic purpura, especially when the presentation includes neurological or extra-renal manifestations. Here, we present a case of SRC who developed a rare neurotoxic complication, posterior reversible encephalopathy syndrome (PRES).A 36-year-old man with a history of diffuse cutaneous systemic sclerosis developed SRC and acute-on-chronic renal failure and ultimately required maintenance hemodialysis. Read More

    The Monro-Kellie Doctrine in Action: Posterior Reversible Leukoencephalopathy Syndrome Caused by Intracranial Hypotension from Lumboperitoneal Shunt Placement.
    World Neurosurg 2017 Feb 23;98:868.e11-868.e15. Epub 2016 Dec 23.
    Department of Radiology, Emory University School of Medicine, Atlanta, Georgia, USA.
    Background: Posterior reversible leukoencephalopathy syndrome (PRES) is linked to various etiologies, including most importantly systemic hypertension. Its association with intracranial hypotension (IH), a potential sequela of various neurosurgical procedures, is underrecognized. We report a case of lumboperitoneal shunt-induced IH resulting in PRES with the goal to increase awareness and elaborate on the potential biologic mechanism, based on the Monro-Kellie hypothesis. Read More

    Posterior Reversible Encephalopathy Syndrome with Extensive Deep White Matter Lesions Including the Temporal Pole.
    Intern Med 2016;55(23):3529-3533. Epub 2016 Dec 1.
    Department of Neurology, Osaka Red Cross Hospital, Japan.
    Posterior reversible encephalopathy syndrome (PRES) typically affects the posterior subcortical white matter. We report the case of a 55-year-old man with atypical PRES, who had malignant hypertension and renal dysfunction. Magnetic resonance imaging of the brain revealed extensive vasogenic edema in the deep white matter including the temporal pole, as well as in the brainstem and cerebellum. Read More

    Sporadic Creutzfeldt-Jakob disease with unusual initial presentation as posterior reversible encephalopathy syndrome: a case report.
    BMC Neurol 2016 Nov 22;16(1):234. Epub 2016 Nov 22.
    Department of Neurology Lithuanian University of Health Sciences, Mickeviciaus str. 9, Kaunas, LT-44307, Lithuania.
    Background: Creutzfeldt - Jakob disease (CJD) is a rapidly progressive and fatal neurodegenerative prion disease. MRI findings are included in diagnostic criteria for probable CJD, giving a sensitivity and specificity more than 90%, but the atypical radiological presentations in the early stage of the disease could cause the diagnostic difficulties. CJD can be definitively diagnosed by histopathological confirmation, brain biopsy or at autopsy. Read More

    Reversible Cerebral Vasoconstriction Syndrome with Transient Splenial Lesions after Delivery.
    Intern Med 2016;55(22):3357-3359. Epub 2016 Nov 15.
    Department of Neurology, Chiba Rosai Hospital, Japan.
    Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by segmental vasospasm and it is often accompanied by either posterior reversible encephalopathy syndrome or stroke. However, other MRI abnormalities have rarely been reported. A 28-year-old woman presented with a thunderclap headache immediately after delivery; MRI showed segmental vasoconstriction and an abnormal signal in the splenium of the corpus callosum. Read More

    A Case of Hypertensive Encephalopathy with Enlarged Optic Nerve Sheath Measured by Transorbital Sonography.
    J Stroke Cerebrovasc Dis 2017 Jan 9;26(1):e20-e21. Epub 2016 Nov 9.
    Department of Stroke Medicine, Kawasaki Medical School, Okayama, Japan.
    This case report describes our experience in using transorbital sonography to evaluate pathological changes in the central nervous system in hypertensive encephalopathy. A 49-year-old man with nausea, headache, and mild confusion was diagnosed with hypertensive encephalopathy by brain magnetic resonance imaging (MRI), which revealed vasogenic edema in the bilateral thalamus and the brain stem. Lumbar puncture showed no severe intracranial hypertension. Read More

    Posterior reversible encephalopathy as the first manifestation of Bickerstaff's brainstem encephalitis.
    BMC Neurol 2016 Nov 8;16(1):215. Epub 2016 Nov 8.
    Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, 112, Taiwan.
    Background: Posterior reversible encephalopathy syndrome (PRES) has been associated with Guillain-Barre syndrome in rare cases. Here we report a patient in whom PRES was the presenting manifestation of Bickerstaff's brainstem encephalitis.

    Case Presentation: A 75-year-old woman presented with acute onset of hypertension, headache, blurred vision, and left eyelid drooping. Read More

    Chemotherapy-associated Posterior Reversible Encephalopathy Syndrome: A Case Report and Review of the Literature.
    Neurologist 2016 Nov;21(6):112-117
    *Barnes-Jewish Hospital †Becker Medical Library ‡Department of Medicine, Division of Oncology §Department of Neurology, Washington University School of Medicine, St Louis, MO.
    Introduction: There are increasing reports of posterior reversible encephalopathy syndrome (PRES) associated with the use of chemotherapeutic agents. Recognition of PRES is crucial given its reversibility with appropriate supportive management. We report a patient presenting with PRES after treatment with Rituximab, Cyclophosphamide, Hydroxydaunorubicin/Adriamycin, Oncovin/Vincristine, Prednisone (R-CHOP) and intrathecal methotrexate. Read More

    Posterior reversible encephalopathy syndrome following a thoracic discectomy-induced dural leak: case report.
    J Neurosurg Spine 2016 Nov 3;25(5):586-590. Epub 2016 Jun 3.
    Norton Neuroscience Institute.
    Posterior reversible encephalopathy syndrome (PRES) is a clinicoradiological syndrome characterized by headaches, altered mental status, seizures, and visual disturbances. Classic MRI findings include white matter changes of the parieto-occipital regions. This syndrome has been encountered in myriad medical illnesses, including hypertension, preeclampsia/eclampsia, and immunosuppressive conditions. Read More

    Selective Oestrogen Receptor Agonists Rescued Hippocampus Parameters in Male Spontaneously Hypertensive Rats.
    J Neuroendocrinol 2016 Oct;28(10)
    Laboratory of Neuroendocrine Biochemistry, Instituto de Biología y Medicina Experimental, Buenos Aires, Argentina.
    Spontaneously hypertensive rats (SHR) show pronounced hippocampus alterations, including low brain-derived neurotrophic factor (BDNF) expression, reduced neurogenesis, astrogliosis and increased aromatase expression. These changes are reverted by treatment with 17β-oestradiol. To determine which oestradiol receptor (ER) type is involved in these neuroprotective effects, we used agonists of the ERα [propylpyrazole triol (PPT)] and the ERβ [diarylpropionitrite (DPN)] given over 2 weeks to 4-month-old male SHR. Read More

    Posterior reversible encephalopathy syndrome in Parkinson disease probably caused by prominent supine hypertension and blood pressure fluctuation.
    Rinsho Shinkeigaku 2016 Nov 21;56(11):754-758. Epub 2016 Oct 21.
    Department of Neurology, Japanese Red Cross Nagoya Daini Hospital.
    We present the case of a 77-year-old man with a 10-year history of Parkinson disease (PD), who developed posterior reversible encephalopathy syndrome (PRES). We diagnosed the case as PRES based on clinical features and MRI findings. He experienced orthostatic hypotension and supine hypertension, including nocturnal hypertension. Read More

    Variant Type of Posterior Reversible Encephalopathy Syndrome with Diffuse Cerebral White Matter and Brainstem Involvement Associated with Intracranial Hemorrhage.
    J Stroke Cerebrovasc Dis 2016 Dec 20;25(12):e233-e235. Epub 2016 Oct 20.
    Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. Electronic address:
    Posterior reversible encephalopathy syndrome (PRES) is a clinical-radiological syndrome characterized by reversible vasogenic edema typically at a posterior location of the cerebrum. PRES with prominent brainstem or basal ganglia involvement is defined as central-variant, which is rare. We herein report an atypical case of a 35-year-old man with a 2-year history of untreated hypertension who complained of recurrent dizziness. Read More

    Prognostic factors in children with PRES and hematologic diseases.
    Acta Neurol Scand 2016 Dec 15;134(6):474-483. Epub 2016 Feb 15.
    Department of Pediatrics, University of L'Aquila, Italy.
    Objectives: Posterior reversible encephalopathy syndrome (PRES) is a clinical and radiological entity characterized by focal neurological signs, headache, confusion, and seizure, associated with transitory lesions in the posterior areas of the brain detectable with neuroimaging. Among children, one of the most common causes of PRES is cancer.

    Materials And Methods: In this review, we present the cases of 5 children developing PRES after stem cell transplantation for hematological disease and review all the cases reported in English literature to investigate outcomes and associated risk factors. Read More

    ED 08-4 DIAGNOSIS AND TREATMENT OF HYPERTENSIVE EMERGENCY IN CHILDREN.
    J Hypertens 2016 Sep;34 Suppl 1 - ISH 2016 Abstract Book:e373-e374
    Capital Institute Of Pediatrics, China.
    According to the seventh report of Joint National Committee (JNC 7), hypertensive emergency (HE), a kind of hypertensive crisis, is defined as a sudden and abrupt elevation in blood pressure so as to cause acute target organ dysfunctions, including central nervous system, cardiovascular system or kidneys. Patients with HE require immediate reduction in markedly elevated blood pressure. Currently, there are no international guidelines for children HE, so the JNC definition is commonly used. Read More

    Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ 2016 Oct 24;188(15):1100-1103. Epub 2016 May 24.
    International Collaboration on Repair Discoveries (Squair, Phillips, Krassioukov), MD/PhD Program (Squair), Department of Radiology, Division of Neuroradiology, Vancouver General Hospital (Harmon), and Department of Medicine, Division of Physical Medicine and Rehabilitation (Krassioukov), University of British Columbia, Vancouver, BC; GF Strong Rehabilitation Centre (Krassioukov), Vancouver Health Authority, Vancouver, BC

    Efficacy of argon plasma coagulation in the management of portal hypertensive gastropathy.
    Endosc Int Open 2016 Oct 6;4(10):E1057-E1062. Epub 2016 Oct 6.
    Internal Medicine Department - Hepatology Division, Zagazig University, Zagazig, Egypt.
    Objectives: Evaluation of the outcome and experience in 2 years of management of portal hypertensive gastropathy (PHG) by argon plasma coagulation (APC) in a cohort of Egyptian cirrhotic patients. Methods: This study was conducted over a 2-year period from January 2011 to February 2013. Upper gastrointestinal endoscopy was performed to evaluate the degree and site of PHG. Read More

    Posterior Reversible Encephalopathy Syndrome: A Comparative Study of Pediatric Versus Adult Patients.
    Pediatr Neurol 2016 Dec 13;65:45-51. Epub 2016 Sep 13.
    Department of Neurology, University of Arkansas for Medical Sciences, Little Rock, Arkansas; Department of Neurology, Ohio State University Wexner Medical Center, Columbus, Ohio. Electronic address:
    Background: Posterior reversible encephalopathy syndrome (PRES) is an acute neurotoxic syndrome that, although characteristically reversible, can result in long-term disability. Our aim was to identify the clinical and radiological factors that are unique to children with PRES compared with adults with the syndrome in a single center.

    Methods: We retrospectively reviewed the clinical and radiological records of all patients with PRES admitted at a tertiary care medical center from 2007 to 2014. Read More

    Predictors of intensive care unit utilization in patients with posterior reversible encephalopathy syndrome.
    Acta Neurol Belg 2017 Mar 28;117(1):201-206. Epub 2016 Sep 28.
    Department of Radiology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
    Posterior reversible encephalopathy syndrome (PRES) is an acute neurological syndrome that requires prompt, aggressive management to improve outcomes. Our aim was to identify factors that would necessitate care in the intensive care unit (ICU) in patients with PRES and the outcomes on discharge following ICU stay. We retrospectively reviewed the medical records and radiological data of adult PRES patients admitted to our tertiary care medical center. Read More

    Allgrove Syndrome: Adrenal Insufficiency with Hypertensive Encephalopathy.
    J Coll Physicians Surg Pak 2016 Sep;26(9):790-2
    Department of Paediatric Endocrinology,The Children's Hospital and ICH, Lahore.
    Allgrove syndrome or triple-Asyndrome is a rare familial multisystem autosomal recessive disorder. It is characterised by triad of alacrima, achalasia and adrenal insufficiency due to adrenocorticotropin hormone (ACTH) resistance. If it is associated with autonomic dysfunction, it is termed as 4-Asyndrome. Read More

    Acute Kidney Injury and Atypical Features during Pediatric Poststreptococcal Glomerulonephritis.
    Int J Nephrol 2016 23;2016:5163065. Epub 2016 Aug 23.
    Division of Nephrology, Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH, USA.
    The most common acute glomerulonephritis in children is poststreptococcal glomerulonephritis (PSGN) usually occurring between 3 and 12 years old. Hypertension and gross hematuria are common presenting symptoms. Most PSGN patients do not experience complications, but rapidly progressive glomerulonephritis and hypertensive encephalopathy have been reported. Read More

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