3,965 results match your criteria Emphysematous Cholecystitis


Dietary Nitrite Attenuates Elastase-Induced Pulmonary Emphysema in a Mouse Model.

Biol Pharm Bull 2018 ;41(12):1818-1823

Division of Pathophysiology, Department of Clinical Dietetics and Human Nutrition, Faculty of Pharmaceutical Science, Josai University.

Pulmonary emphysema (PE) is a major pathological feature of chronic obstructive pulmonary disease (COPD) and is characterized by proteolytic destruction of the alveolar structure and subsequent inflammation of the respiratory tract. We hypothesized that nitrite attenuates the development of PE via anti-inflammatory actions. PE was induced by intratracheal instillation of porcine pancreas elastase (PPE) in mice. Read More

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January 2018

B Cells Produce the Tissue-Protective Protein RELMα during Helminth Infection, which Inhibits IL-17 Expression and Limits Emphysema.

Cell Rep 2018 Dec;25(10):2775-2783.e3

Center for Immunity and Inflammation, New Jersey Medical School, Rutgers-The State University of New Jersey, Newark, NJ 07101, USA; Department of Medicine, New Jersey Medical School, Rutgers-The State University of New Jersey, Newark, NJ 07101, USA. Electronic address:

Emphysema results in destruction of alveolar walls and enlargement of lung airspaces and has been shown to develop during helminth infections through IL-4R-independent mechanisms. We examined whether interleukin 17A (IL-17A) may instead modulate development of emphysematous pathology in mice infected with the helminth parasite Nippostrongylus brasiliensis. We found that transient elevations in IL-17A shortly after helminth infection triggered subsequent emphysema that destroyed alveolar structures. Read More

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December 2018

Diclofenac Sodium Treatment Ameliorates Extrapancreatic Organ Injuries in a Murine Model of Acute Pancreatitis Induced by Caerulein.

Gastroenterol Res Pract 2018 31;2018:9829208. Epub 2018 Oct 31.

Necmettin Erbakan University, Meram School of Medicine, Department of Pathology, Turkey.

Aim: We determined the effects of diclofenac sodium, octreotide, and their combination on extrapancreatic organ injuries in caerulein-induced acute pancreatitis in mice.

Methods: A total of 58 BALB-C male mice (25 g) were divided into seven groups and used to create a caerulein-induced acute pancreatitis model. Diclofenac sodium, octreotide, and their combination were given for treatment of caerulin-induced acute pancreatitis in mice. Read More

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October 2018

Emphysematous Cystitis.

J Belg Soc Radiol 2018 Oct 12;102(1):66. Epub 2018 Oct 12.

Sint-Andriesziekenhuis, Tielt, BE.

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October 2018

Infectious and Inflammatory Diseases of the Urinary Tract: Role of MR Imaging.

Magn Reson Imaging Clin N Am 2019 Feb 29;27(1):59-75. Epub 2018 Oct 29.

Department of Radiology, Hospital Garcia de Orta, Av. Torrado da Silva, 2805-267 Almada, Portugal; Department of Radiology, Hospital da Luz, Estrada Nacional 10, km 37, Setúbal 2900-722, Portugal. Electronic address:

Urinary tract infection (UTI) is among the most common of bacterial infections. Imaging studies are only required in cases of complicated UTIs. Ultrasound remains the first-line imaging method; however, CT is the gold standard for evaluation of UTIs. Read More

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February 2019
3 Reads

Heterogeneous burden of lung disease in smokers with borderline airflow obstruction.

Respir Res 2018 Nov 20;19(1):223. Epub 2018 Nov 20.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Utah, 26 N 1900 E, Salt Lake City, UT, 84132, USA.

Background: The identification of smoking-related lung disease in current and former smokers with normal FEV is complex, leading to debate regarding using a ratio of forced expiratory volume in 1 s to forced vital capacity (FEV/FVC) of less than 0.70 versus the predicted lower limit of normal (LLN) for diagnosis of airflow obstruction. We hypothesized that the discordant group of ever-smokers with FEV/FVC between the LLN and 0. Read More

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November 2018
4 Reads

History of lung volume reduction procedures.

J Thorac Dis 2018 Oct;10(Suppl 27):S3326-S3334

Dipartimento Cardio-Toraco-Vascolare, University of Milan Bicocca, Respiratory Unit, San Gerardo Hospital, ASST di Monza, Monza, Italy.

Lung volume reduction (LVR) procedures for emphysematous patients were firstly introduced in the second half of the twentieth century. Over time, from the first invasive surgical procedures, new less invasive techniques have been conceived. In regards to the surgical approach, the adoption of VATS and the execution, in selected centers, of a non-resectional approach, with folding of less functional lung tissue, reduced mortality and adverse events risks. Read More

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October 2018
2 Reads

[Emphysematous cystitis in a patient with type-1diabetes mellitus - diagnostic difficulties].

Wiad Lek 2018 ;71(7):1424-1428

Katedra I Zakład Medycyny Rodzinnej, Warszawski Uniwersytet Medyczny, Warszawa, Polska.

A case report of 28 year old female with medical history of bed controlled type 1 diabetes mellitus complicated by autonomic neuropathy in the form of gastroparesis, suffered by emphysematous cystitis caused by Escherichia coli was described. Emphysematous cystitis is a rare urinary tract infection connected with the presence of gas in the bladder lumen or/and within the bladder wall, which occurs mainly in women, in older age, suffering from type 2 diabetes, complicated by microangiopathy, neuropathy, with urinary tract obstruction and weakness of immunity system. Diagnostic difficulties and the delay in correct diagnosis in described case were caused by the dominated complaint of the upper gastrointestinal tract and difficulties in interpretation of imaging methods, such as abdominal X-ray and ultrasound scan. Read More

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January 2018
4 Reads

A case of bilateral emphysematous pyelonephritis caused by Candida albicans.

J Infect Chemother 2018 Nov 15. Epub 2018 Nov 15.

Second Department of Internal Medicine, Nagasaki University, Nagasaki, Japan; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.

Emphysematous pyelonephritis (EPN) is a life-threatening renal infection characterized by the formation of gas within the renal parenchyma and collecting duct system, as well as perinephric tissues. We herein report a case of bilateral EPN accompanied by the urinary tract infection caused by spherical growth of Candida albicans in a patient with underlying diabetes mellitus and prostate cancer. The diagnosis was assisted by computed tomography, urography, and gram staining. Read More

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November 2018
6 Reads

Simultaneous occurrence of hypermucoviscous emphysematous prostatic abscess, emphysematous cystitis, and renal abscess.

IDCases 2018 3;14:e00464. Epub 2018 Nov 3.

Division of General Medicine, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, 173-8610, Japan.

Emphysematous prostatic abscess is a rare clinical entity of uncomplicated urinary tract infections with high mortality rate. Here we report a case of hypermucoviscous causing emphysematous prostatic abscess, emphysematous cystitis, and renal abscess simultaneously in a 75-year-old Japanese male with diabetes mellitus and advanced gastric cancer. The patient was successfully treated with prolonged intravenous antimicrobial agents. Read More

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November 2018
2 Reads

Perforated emphysematous cholecystitis and Streptococcus bovis.

Rev Esp Enferm Dig 2018 Nov 13;111. Epub 2018 Nov 13.

Cirugía General y del Aparato Digestivo, Hospital Universitario de La Princesa, España.

Streptococcus bovis is an uncommon cause of biliary tract infection, being acute cholecystitis including this microorganism extremely rare. This entity is more frequent in older patients with cardiovascular disease, diabetes, hepatitis, or neoplasms as colon cancer. Read More

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November 2018
2 Reads

Reduced Forced Vital Capacity among HIV-infected middle-aged individuals.

J Infect Dis 2018 Nov 12. Epub 2018 Nov 12.

Department of Global Health and Internal Medicine, Amsterdam Infection and Immunity Institute and Amsterdam Public Health Research Institute, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.

Introduction: Pulmonary function impairments are more common among people living with HIV (PWH), as are contributing risk behaviors. To understand the effects of HIV infection independent of risk behaviors, pulmonary function was evaluated in lifestyle comparable HIV-positive and -negative AGEhIV-cohort participants.

Methods: Prevalence of obstructive lung disease in 544 HIV-positive and 529 HIV-negative participants was determined using spirometry. Read More

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November 2018
2 Reads

Emphysematous pyelonephritis in renal allograft related to antibody-mediated rejection: A case report and literature review.

Transpl Infect Dis 2018 Nov 9:e13026. Epub 2018 Nov 9.

Department of Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, Michigan.

Emphysematous pyelonephritis (EPN) is a rare condition which can rapidly progress to sepsis and multiple organ failure with high mortality. We experienced a rare case of EPN in a renal allograft related to antibody-mediated rejection (AMR). The patient received a deceased donor kidney transplant due to end-stage renal disease secondary to diabetes mellitus. Read More

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November 2018
11 Reads

Inflammatory signature in lung tissues in patients with combined pulmonary fibrosis and emphysema.

Biomarkers 2018 Nov 9:1-8. Epub 2018 Nov 9.

a Center for Inflammation, Translational and Clinical Lung Research, Lewis Katz School of Medicine , Temple University , Philadelphia , PA , USA.

Background: The aetiology and inflammatory profile of combined pulmonary fibrosis and emphysema (CPFE) remain uncertain currently.

Objective: We aimed to examine the levels of inflammatory proteins in lung tissue in a cohort of patients with emphysema, interstitial pulmonary fibrosis (IPF), and CPFE.

Materials And Methods: Explanted lungs were obtained from subjects with emphysema, IPF, CPFE, (or normal subjects), and tissue extracts were prepared. Read More

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November 2018
5 Reads

Emphysematous pyelonephritis and cystitis in a patient with uremia and anuria: A case report and literature review.

Medicine (Baltimore) 2018 Nov;97(45):e11272

Department of Nephrology, Qilu Hospital of Shandong University (Qingdao).

Introduction: Emphysematous pyelonephritis (EPN) or cystitis (EC) is a severe infection of the urinary tract with high mortality. EPN is uncommon among the patients of end stage of renal failure (ESRD) CASE PRESENTATION:: A 38-year-old male with uremia and anuria who was on hemodialysis was found to have gas formation in the bilateral pelvis, ureters, and urinary bladder by CT scan. The diagnosis was emphysematous pyelonephritis and cystitis. Read More

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November 2018
20 Reads

A rare x-ray image of emphysematous cystitis.

Urol Case Rep 2019 Jan 25;22:40-41. Epub 2018 Oct 25.

Princess Alexandra Hospital, 199 Ipswich Road, Woolloongabba, Queensland, 4102, Australia.

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January 2019

ACR Appropriateness Criteria Acute Pyelonephritis.

J Am Coll Radiol 2018 Nov;15(11S):S232-S239

Specialty Chair, University of Alabama at Birmingham, Birmingham, Alabama.

Pyelonephritis refers to infection involving the renal parenchyma and renal pelvis. In most patients, uncomplicated pyelonephritis is diagnosed clinically and responds quickly to appropriate antibiotic treatment. If treatment is delayed, the patient is immunocompromised, or for other reasons, microabscesses that form during the acute phase of pyelonephritis may coalesce, forming a renal abscess. Read More

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November 2018
5 Reads
2.280 Impact Factor

Hemothorax after emphysematous bullectomy using a linear staple device with bioabsorbable polyglycolic acid felt.

J Surg Case Rep 2018 Oct 26;2018(10):rjy289. Epub 2018 Oct 26.

Division of General Thoracic Surgery, Department of Surgery, Shiga University of Medical Science, Setatsukinowa-cho, Otsu, Shiga, Japan.

A linear stapler with bioabsorbable polyglycolic acid felt is widely used during the resection of emphysematous lung. Currently, an improved staple device with polyglycolic acid felt is being used owing to a history of complications, such as bleeding, that was associated with the previous model. Here, we report a case of a 69-year-old man who presented to our department for treatment of left lower lobe lung cancer using the new staple device. Read More

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October 2018
9 Reads

Heme scavenging reduces pulmonary endoplasmic reticulum stress, fibrosis, and emphysema.

JCI Insight 2018 Nov 2;3(21). Epub 2018 Nov 2.

Department of Anesthesiology and Perioperative Medicine, Division of Molecular and Translational Biomedicine.

Pulmonary fibrosis and emphysema are irreversible chronic events after inhalation injury. However, the mechanism(s) involved in their development remain poorly understood. Higher levels of plasma and lung heme have been recorded in acute lung injury associated with several insults. Read More

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November 2018
2 Reads

Radiographic and ultrasonographic findings in a dog with emphysematous pyometra.

Acta Vet Scand 2018 Oct 29;60(1):67. Epub 2018 Oct 29.

Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden.

Background: Emphysematous pyometra is a rare canine disease characterized by gas-forming bacteria infecting the uterus and causing an accumulation of both gas and infectious exudate in the uterine lumen. While radiological features of emphysematous pyometra have been previously described in dogs, the ultrasonographic appearance has not been reported.

Case Presentation: A 7-year-old intact female Labrador Retriever was presented because of a 1 day history of vomiting, anorexia, mild polyuria/polydipsia and signs of fatigue. Read More

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October 2018

ATRA reduces inflammation and improves alveolar epithelium regeneration in emphysematous rat lung.

Biomed Pharmacother 2018 Dec 6;108:1435-1450. Epub 2018 Oct 6.

Department of Biotechnology, School of Biotechnology, Gautam Buddha University, Greater Noida, 201308, Uttar Pradesh, India. Electronic address:

Introduction: Pulmonary emphysema characterized by alveolar wall destruction is resultant of persistent chronic inflammation. All-trans retinoic acid (ATRA) has been reported to reverse elastase-induced emphysema in rats. However, the underlying molecular mechanisms are so far unknown. Read More

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December 2018
3 Reads

Intramedullary Antibiotic Delivery for Emphysematous Osteomyelitis of the Femur.

Orthopedics 2018 Oct 26:1-3. Epub 2018 Oct 26.

The authors present a case of bilateral femoral emphysematous osteomyelitis caused by Escherichia coli in a 60-year-old woman with rheumatoid arthritis who was receiving long-term prednisone therapy. The infection in both femoral shafts was eradicated with surgical debridement, followed by insertion of intramedullary rods composed of culture-specific antibiotic cement into the femoral canals in conjunction with 6 weeks of intravenous antibiotics. The rods were subsequently removed, and no signs of further osteomyelitis were recognized at follow-up. Read More

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October 2018
2 Reads

Emphysematous cholecystitis and cholecystocolic fistula.

Acta Chir Belg 2018 Oct 29:1-2. Epub 2018 Oct 29.

a Department of General and Digestive Surgery , Hospital Universitario de la Princesa , Madrid , Spain.

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October 2018
4 Reads

Fulminant Emphysematous Pancreatic Pseudocyst: Infected with Normal Skin Flora.

Am J Med 2018 Oct 24. Epub 2018 Oct 24.

Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.

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October 2018

Emphysematous pyelonpehritis in a dual kidney transplant recipient.

Nephrology (Carlton) 2018 11;23(11):1064-1065

Renal Unit, Royal Prince Alfred Hospital, Sydney Local Health District, Sydney, New South Wales, Australia.

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November 2018

Spontaneous Hepatic Hemorrhage Caused by Emphysematous Cholecystitis: A Case Report and Literature Review.

Surg Infect (Larchmt) 2018 Oct 23. Epub 2018 Oct 23.

3 Zhuji Central Hospital , Zhuji, Shaoxin, Zhejiang Province, China .

Background: Emphysematous cholecystitis and spontaneous hepatic hemorrhage are uncommon and serious conditions with non-specific presentations that can lead to a poor clinical outcome. We report a case of spontaneous hepatic hemorrhage of emphysematous cholecystitis. A 49-year-old male presented to the emergency department with fever, chills, right upper quadrant pain, vomiting, and diarrhea of four days' duration. Read More

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October 2018
4 Reads

A pathology requiring urgent cholecystectomy : emphysematous cholecystitis.

Acta Gastroenterol Belg 2018 Jul-Sep;81(3):449-450

Izmir Katip Celebi University Ataturk Training and Research Hospital, General Surgery Department, Izmir-Turkey.

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October 2018
2 Reads

Alpha-1 antitrypsin deficiency as a common treatable mechanism in chronic respiratory disorders and for conditions different from pulmonary emphysema? A commentary on the new European Respiratory Society statement.

Multidiscip Respir Med 2018 8;13:39. Epub 2018 Oct 8.

1Department of Pathophysiology and Transplantation, University of Milano; Internal Medicine Department, Respiratory Unit and Adult Cystic Fibrosis Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.

Background: The European Respiratory Society recently published an important statement reviewing available evidence on diagnosis and treatment of lung disease associated to alpha-1 antitrypsin deficiency (AATD). Several issues on this topic still remain unresolved and subject of interpretation according to different standard procedures and healthcare systems worldwide. The purpose of this commentary is to offer a critical contribution to most of these controversial issues in light of an Italian perspective for the management of this disease. Read More

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October 2018
3 Reads

Effects of Antioxidant Tempol on Systematic Inflammation and Endothelial Apoptosis in Emphysematous Rats Exposed to Intermittent Hypoxia.

Yonsei Med J 2018 Nov;59(9):1079-1087

Respiratory Department of Tianjin Medical University General Hospital, Tianjin, China.

Purpose: Obstructive sleep apnea and chronic obstructive pulmonary disease are independent risk factors of cardiovascular disease (CVD), and their coexistence is known as overlap syndrome (OS). Endothelial dysfunction is the initial stage of CVD; however, underlying mechanisms linking OS and CVD are not well understood. The aim of this study was to explore whether OS can lead to more severe inflammation and endothelial apoptosis by promoting endothelial dysfunction, and to assess the intervention effects of antioxidant tempol. Read More

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November 2018
2 Reads
1.260 Impact Factor

Complicated bilateral fungal emphysematous pyelonephritis in a 55-year-old diabetic female: A case report and review of literature.

Curr Med Mycol 2018 Jun;4(2):32-35

Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medial Sciences, Tehran, Iran.

Background And Purpose: Emphysematous pyelonephritis (EPN) is a rare and serious disease causing acute renal failure. Diabetes is a major risk factor for this infection.

Case Report: Herein, we present the case of a 55-year-old female patient with diabetes and EPN caused by . Read More

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June 2018
8 Reads

Canine and feline emphysematous gastritis may be differentiated from gastric emphysema based on clinical and imaging characteristics: Five cases.

Vet Radiol Ultrasound 2018 Oct 11. Epub 2018 Oct 11.

The Royal (Dick) School of Veterinary Studies and Roslin Institute, The University of Edinburgh, Roslin, EH25 9RG, UK.

Gastric pneumatosis is an imaging finding defined as the presence of gas foci in the gastric wall. In humans, this imaging feature can result from one of two separate clinical entities: life-threatening emphysematous gastritis or clinically benign gastric emphysema. This retrospective case series study describes the clinical and imaging features in five animals diagnosed with spontaneous gastric pneumatosis without gastric dilatation-volvulus. Read More

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October 2018
1 Read

Low-dose CT screening for lung cancer reduced lung cancer mortality in Hitachi City.

Authors:
Takeshi Nawa

Int J Radiat Biol 2018 Oct 11:1-6. Epub 2018 Oct 11.

a Department of Respiratory Medicine , Hitachi General Hospital Hitachi Ltd , Hitachi City , Japan.

Purpose: To detect early, curable lung cancer, screening using low-dose CT (CT screening) was initiated in Japan and Western countries around the early 1990s.

Material And Methods: In 2013, the National Lung Screening Trial (NLST) reported that annual CT screening for high-risk participants leads to a 16% reduction in lung cancer death. In Hitachi City, CT screening for citizens 50 years of age or older was started in 1998, and 30% of the citizens had received a CT examination at least once by 2006. Read More

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October 2018

Emphysematous infection of a solitary renal cyst: A case report and literature review.

Urol Case Rep 2019 Jan 28;22:1-2. Epub 2018 Sep 28.

Department of Urology, La Rabta University Hospital, Tunisia.

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January 2019
4 Reads

Imaging Advances in Chronic Obstructive Pulmonary Disease: Insights from COPDGene.

Am J Respir Crit Care Med 2018 Oct 10. Epub 2018 Oct 10.

National Jewish Health, Radiology, Denver, Colorado, United States.

The Genetic Epidemiology of Chronic Obstructive Pulmonary Disease (COPDGene) study, which began in 2007, is an ongoing multicenter observational cohort study of >10,000 current and former smokers, aimed at understanding the etiology, progression, and heterogeneity of COPD. In addition to genetic analysis, the participants have been extensively characterized by clinical questionnaires, spirometry, volumetric inspiratory and expiratory CT, and longitudinal follow-up, including follow-up CT at five years after enrollment. The purpose of this review is to summarize the major advances in our understanding of COPD resulting from the imaging findings in the COPDGene study. Read More

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October 2018
2 Reads

Emphysematous gastritis in a cat.

J Vet Emerg Crit Care (San Antonio) 2018 Nov 9;28(6):596-602. Epub 2018 Oct 9.

Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL 36849.

Objective: To describe the presentation, diagnosis, treatment, and outcome of a case of emphysematous gastritis (EG) in a cat.

Case Series Summary: A 15-year-old female neutered domestic short-hair cat presented for a 4-month history of weight loss and intermittent vomiting. Clinicopathologic and imaging findings suggested an underlying primary gastrointestinal (GI) disease, as well as possible hepatobiliary disease. Read More

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November 2018
2 Reads

CT Imaging-Based Low-Attenuation Super Clusters in Three Dimensions and the Progression of Emphysema.

Chest 2018 Oct 5. Epub 2018 Oct 5.

Department of Biomedical Engineering, Boston University College of Engineering, Boston, MA. Electronic address:

Background: Distributions of low-attenuation areas in two-dimensional (2-D) CT lung slices are used to quantify parenchymal destruction in patients with COPD. However, these segmental approaches are limited and may not reflect the true three-dimensional (3-D) tissue processes that drive emphysematous changes in the lung. The goal of this study was to instead evaluate distributions of 3-D low-attenuation volumes, which we hypothesized would follow a power law distribution and provide a more complete assessment of the mechanisms underlying disease progression. Read More

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October 2018
3 Reads

A rare case of emphysematous osteomyelitis of spine in uncontrolled diabetes mellitus.

Med Intensiva 2018 Oct 3. Epub 2018 Oct 3.

Department of Internal Medicine, Max Super Speciality Hospital, Vaishali, Ghaziabad 201012, India.

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October 2018
4 Reads

PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis.

Autophagy 2018 Oct 5:1-17. Epub 2018 Oct 5.

a Division of Respiratory Diseases, Department of Internal Medicine , Jikei University School of Medicine , Tokyo , Japan.

Cigarette smoke (CS)-induced accumulation of mitochondrial damage has been widely implicated in chronic obstructive pulmonary disease (COPD) pathogenesis. Mitophagy plays a crucial role in eliminating damaged mitochondria, and is governed by the PINK1 (PTEN induced putative protein kinase 1)-PRKN (parkin RBR E3 ubiquitin protein ligase) pathway. Although both increased PINK1 and reduced PRKN have been implicated in COPD pathogenesis in association with mitophagy, there are conflicting reports for the role of mitophagy in COPD progression. Read More

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October 2018
3 Reads

Vacuum-Assisted Closure (VAC) Using Multiple Foam Pieces for Hidden Space Drainage through Less Exposure in Musculoskeletal Infections.

J Hand Surg Asian Pac Vol 2018 Sep;23(3):369-376

* Department of Orthopedic Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Background: Purulent musculoskeletal infections often require surgical debridement and drainage. However, when the infection is extensive or involving multiple layers of tissues, maintaining drainage of the involved spaces can be difficult, even with the application of vacuum-assisted closure (VAC) therapy. Wide exposure and aggressive debridement is often required for such cases, which in turn may complicate wound coverage. Read More

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September 2018
2 Reads

Rapidly Fatal Emphysematous Osteomyelitis with Multiple Septic Emboli and Liver Abscess Caused by .

Infect Chemother 2018 Sep;50(3):268-273

Department of Internal Medicine, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea.

Emphysematous osteomyelitis, characterized by intraosseous gas, is a rare but potentially fatal condition that requires prompt diagnosis and aggressive therapy. Causative organisms are members of the bacterial family or anaerobes in most cases and significant comorbidities such as diabetes mellitus and malignancy, may predispose an individual to the development of emphysematous osteomyelitis. We report a case of extensive emphysematous osteomyelitis via hematogenous spread from liver abscess, complicated by gas-containing abscesses in adjacent soft tissues and epidural space, and multiple systemic septic emboli in a diabetic patient. Read More

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September 2018
1 Read

Emphysematous liver abscess in a 58-year-old woman.

CMAJ 2018 Sep;190(37):E1111

Department of Emergency Medicine, Chi-Mei Medical Center, Yongkang District, Tainan, Taiwan

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September 2018
5 Reads
5.960 Impact Factor

Copper as the most likely pathogenic divergence factor between lung fibrosis and emphysema.

Med Hypotheses 2018 Nov 14;120:49-54. Epub 2018 Aug 14.

Department of Respiratory Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.

Although fibrosis and emphysema are in many ways on opposite ends of the pulmonary parenchymal disease spectrum, they seem to share common pathomechanistic steps. This is illustrated by the coexistence of both entities in lungs of individuals with combined pulmonary fibrosis and emphysema. Macroproteins elastin and collagen are major constituents of the pulmonary extracellular matrix. Read More

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November 2018
5 Reads

Successful lung volume reduction surgery in combined pulmonary emphysema and fibrosis without body-plethysmographic hyperinflation-a case report.

J Thorac Dis 2018 Aug;10(Suppl 23):S2830-S2834

Department of Pulmonology, University Hospital Zurich, 8091 Zurich, Switzerland.

Surgical and bronchoscopic lung volume reduction (LVR) have been demonstrated to improve lung function, dyspnea and quality of life in patients with severe pulmonary emphysema. The most important functional prerequisite for a successful LVR is hyperinflation measured by body plethysmography. A residual volume (RV) of more than 180% predicted and a RV/total lung capacity (TLC) ratio of more than 0. Read More

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August 2018
4 Reads

Valve therapy in patients with emphysematous type of chronic obstructive pulmonary disease (COPD): from randomized trials to patient selection in clinical practice.

J Thorac Dis 2018 Aug;10(Suppl 23):S2780-S2796

Department of Respiratory and Critical Care Medicine, Ludwig-Boltzmann-Institute for COPD and Respiratory Epidemiology, Otto-Wagner-Spital, Sanatoriumsstrasse 2, 1140 Wien, Austria.

In recent years a number of endoscopic methods have emerged to treat patients with severe emphysematous type of chronic obstructive pulmonary disease (COPD), who are primarily symptomatic due to hyperinflation despite optimal medical management. Of these techniques, implantation of endobronchial one-way valves into targeted airways of isolated emphysematous lobes appears to be one of the most promising innovations. Results from randomized controlled trials of valve therapy for emphysema show consistent benefits in terms of lung function, exercise capacity, symptoms, and quality of life. Read More

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August 2018
8 Reads

Staged unilateral lung volume reduction surgery: from mini-invasive to minimalist treatment strategies.

J Thorac Dis 2018 Aug;10(Suppl 23):S2754-S2762

Department of Radiology, Policlinico Tor Vergata University, Rome, Italy.

Lung volume reduction surgery (LVRS) entailing unilateral or bilateral non-anatomical resection of severely damaged emphysematous tissue carried out by thoracoscopic or open surgical approaches, under general anesthesia with single-lung ventilation, has resulted in significant and long-lasting clinical and functional benefit. Unfortunately, the morbidity rates reported by simultaneous bilateral resectional LVRS has led to raise criticism regarding its cost-effectiveness and has stimulated in recent years the development of less invasive bronchoscopic and surgical non-resectional methods of treatment that are preferentially performed in a staged unilateral fashion. We had previously proposed an innovative LVRS modality, which did not entail any resection of lung tissue and was electively carried out according to a staged unilateral strategy by a multiport thoracoscopic access, through thoracic epidural anesthesia in conscious, spontaneously ventilating patients (awake LVRS). Read More

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August 2018
11 Reads

Lung volume reduction surgery in hypercapnic patients: a single-center experience from China.

J Thorac Dis 2018 Aug;10(Suppl 23):S2698-S2703

Department of Thoracic Surgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.

Background: Lung volume reduction surgery (LVRS) has shown early promise as a palliative therapy in severe emphysema, but with a controversy over its indications. The aim of this study was to evaluate whether patients with hypercapnia should be excluded from LVRS.

Methods: Total 15 cases of severe emphysema with the level of PaCO exceeding 50 mmHg were retrospectively studied. Read More

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August 2018
1 Read

Emphysematous pyelonephritis: outcomes of conservative management and literature review.

BMJ Case Rep 2018 Sep 12;2018. Epub 2018 Sep 12.

Department of Cardiology, Frimley Health Foundation Trust, Slough, Berkshire, UK.

Emphysematous pyelonephritis (EPN) is a rare, necrotising infection of the renal parenchyma, predominantly associated with infection and unless promptly recognised and dealt with, it carries a poor prognosis. The current treatment is one of antimicrobial therapies together with nephrectomy in a majority of patients. We report an elderly man with multiple comorbidities with a diagnosis of EPN whose condition improved with antimicrobial and supportive therapy, and no surgical intervention was required. Read More

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September 2018
3 Reads

A Case of Acute Respiratory Distress Syndrome Caused by Waterproofing Spray Inhalation.

Tokai J Exp Clin Med 2018 Sep 20;43(3):106-110. Epub 2018 Sep 20.

Department of Emergency and Critical Care Medicine, Odawara Municipal Hospital, 46 Kuno, Odawara, Kanagawa 250-8558, Japan.

We report the case of a 62-year-old man who used approximately one can of waterproofing spray in an enclosed room and, then, smoked a cigarette. He developed a fever of 39°C with respiratory distress and was transported by ambulance to his usual doctor. Since his respiratory state was very severe, he was transferred to our hospital. Read More

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September 2018
15 Reads

Radiotherapy of lung cancers: FFF beams improve dose coverage at tumor periphery compromised by electronic disequilibrium.

Phys Med Biol 2018 Sep 28;63(19):195007. Epub 2018 Sep 28.

Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, United States of America. Author to whom any correspondence should be addressed.

The purpose of this work was to investigate radiotherapy underdosing at the periphery of lung tumors, and differences in dose for treatments delivered with flattening filter-free (FFF) beams and with conventional flattened (FF) beams. The true differences between these delivery approaches, as assessed with Monte Carlo simulations, were compared to the apparent differences seen with clinical treatment planning algorithms AAA and Acuros XB. Dose was calculated in a phantom comprised of a chest wall, lung parenchyma, and a spherical tumor (tested diameters: 1, 3, and 5 cm). Read More

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September 2018
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