359,076 results match your criteria Emergency Medicine Journal[Journal]


Selective Activation of Cannabinoid Receptor 2 Attenuates Myocardial Infarction via Suppressing NLRP3 Inflammasome.

Inflammation 2018 Dec 15. Epub 2018 Dec 15.

Department of Cardiology, Zhejiang Hospital, 12 Lingyin Road, Zhejiang, Hangzhou, China.

The administration of cannabinoid receptor 2 (CB2R) agonist has been reported to produce a cardioprotective effect against the pathogenesis and progression of myocardial infarction (MI). Here in this study, we investigated the specific mechanism related to inflammatory suppression. JWH-133 was used for the activation of CB2R. Read More

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December 2018

Consensus Statement of the Italian Society of Colorectal Surgery (SICCR): management and treatment of complete rectal prolapse.

Tech Coloproctol 2018 Dec 15. Epub 2018 Dec 15.

Department of Colorectal Surgery, Santa Rita Clinic, Vercelli, Italy.

Rectal prolapse, rectal procidentia, "complete" prolapse or "third-degree" prolapse is the full-thickness prolapse of the rectal wall through the anal canal and has a significant impact on quality of life. The incidence of rectal prolapse has been estimated to be approximately 2.5 per 100,000 inhabitants with a clear predominance among elderly women. Read More

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December 2018
1 Read

Pharmacokinetics of meropenem in plasma and cerebrospinal fluid in patients with intraventricular hemorrhage after lateral ventricle drainage.

Eur J Clin Pharmacol 2018 Dec 15. Epub 2018 Dec 15.

Department of Emergency Internal Medicine, The First Affiliated Hospital of Bengbu Medical College, Bengbu, 233004, China.

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December 2018

A Mediterranean Diet with an Enhanced Consumption of Extra Virgin Olive Oil and Pistachios Improves Pregnancy Outcomes in Women Without Gestational Diabetes Mellitus: A Sub-Analysis of the St. Carlos Gestational Diabetes Mellitus Prevention Study.

Ann Nutr Metab 2018 Dec 14;74(1):69-79. Epub 2018 Dec 14.

Department of Endocrinology and Nutrition, Hospital Clínico Universitario San Carlos and Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid,

Aims: The aim of the study was to evaluate the effect of a Mediterranean diet (MedDiet), enhanced with extra virgin olive oil (EVOO) and nuts, on a composite of adverse maternofoetal outcomes of women with normoglycemia during pregnancy.

Methods: This was a sub-analysis of the St Carlos gestational diabetes mellitus Prevention Study. Only normoglycemic women were analysed (697). Read More

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December 2018
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Use of supplemental oxygen in emergency patients: a systematic review and recommendations for military clinical practice.

J R Army Med Corps 2018 Dec 15. Epub 2018 Dec 15.

Emergency Department, University Hospitals Plymouth NHS Trust, Plymouth, UK.

Introduction: Supplemental oxygen is a key element of emergency treatment algorithms. However, in the operational environment, oxygen supply poses a challenge. The lack of high-quality evidence alongside emerging technologies provides the opportunity to challenge current guidelines. Read More

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December 2018

Atypical ischemic repolarization in right bundle branch block.

J Electrocardiol 2018 Dec 6;52:117-118. Epub 2018 Dec 6.

Department "A" Medical Area, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano 1, Belisario Domínguez - Sección XVI, Tlalpan, Mexico City PO 14080, Mexico.

A 70-year-old male presented to emergency room 16 h after the onset of acute chest pain. Initial ECG showed sinus rhythm with a wide QRS and right bundle branch block (RBBB) with concordant and symmetric T waves in V1-V2. A plausible explanation for the atypical positive T waves in leads V1-V2 in conjunction with RBBB could be non-reperfused lateral MI (LMI) as a "mirror-image" of inverted T waves in the posterior leads V7-V9. Read More

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December 2018

PERK is essential for proliferation of intestinal stem cells in mice.

Exp Cell Res 2018 Dec 14. Epub 2018 Dec 14.

Division of Emergency Medicine, Department of General Internal Medicine, Department of Emergency Intensive Care Unit, The First Affiliated Hospital of Sun Yat-sen University, No.58, Zhongshan 2nd Road, Guangzhou, 510080, China. Electronic address:

Protein kinase RNA-like Endoplasmic Reticulum Kinase (PERK) is an endoplasmic reticulum stress sensor that possesses pro-survival capability and contributes to cell homeostasis and survival. Leucine-rich repeat-containing G-protein coupled receptor 5 (Lgr5) has been recognized as a stem cell marker in intestinal epithelial cells. To determine whether PERK modulates the proliferation of intestinal stem cells, we investigated the effects of PERK knock-down on intestinal Lgr5-positive stem cells in mice. Read More

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December 2018

Healthcare Costs of Secondhand Smoke Exposure at Home for U.S. Children.

Am J Prev Med 2018 Dec 12. Epub 2018 Dec 12.

Institute for Health and Aging, School of Nursing, University of California, San Francisco, San Francisco, California.

Introduction: The purpose of this study is to estimate healthcare utilization and healthcare costs due to secondhand smoke exposure at home for children in the U.S.

Methods: Using data from the 2000, 2005, and 2010 U. Read More

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December 2018

Contrast-Enhanced Ultrasound Reveals That Lipoprotein Apheresis Improves Myocardial But Not Skeletal Muscle Perfusion.

Authors:
Carlo Caiati

JACC Cardiovasc Imaging 2018 Dec 6. Epub 2018 Dec 6.

Unit of Cardiovascular Diseases, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy. Electronic address:

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December 2018

[Autochthonous hydatid cyst of the lung].

Ann Pathol 2018 Dec 12. Epub 2018 Dec 12.

Département de pathologie, CHU Bichat-Claude-Bernard, AP-HP, 46, rue Henri-Huchard, 75018 Paris, France. Electronic address:

Cystic echinococcosis, or hydatidosis, also known as hydatid cyst, is a cosmopolitan parasitosis mainly present in breeding areas. This anthropozoonosis is related to the tissue development of an hydatid of an echinococcus tænia, Echinococcus granulosus, found in the digestive tract of canids, at the adult state. In France, this larval cestosis is essentially an import disease developed by patients from endemic areas such as East and North Africa, South America or Asia. Read More

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December 2018

The "myth" of iodine allergy to radiocontrast in Emergency Medicine.

Am J Emerg Med 2018 Dec 8. Epub 2018 Dec 8.

University of Missouri-Columbia, Department of Emergency Medicine, United States of America.

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December 2018

Push dose pressors: Experience in critically ill patients outside of the operating room.

Am J Emerg Med 2018 Dec 3. Epub 2018 Dec 3.

Department of Emergency Medicine, University of Rochester Medical Center, 601 Elmwood Ave., Box 655, Rochester, NY 14642, United States of America; Department of Pharmacy, University of Rochester Medical Center, 601 Elmwood Ave., Box 638, Rochester, NY 14642, United States of America. Electronic address:

Purpose: Evaluate push dose vasopressor (PDP) practice patterns, efficacy, and safety in critically ill patients.

Methods: Critically ill patients receiving phenylephrine or ephedrine PDP from November 2015-March 2017 were included. Patient demographics, medication administration details, vital signs pre- and post-administration, adverse effects, and medications errors were collected. Read More

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December 2018

An unexpected cause of chronic cough in a young woman: Tachycardia-induced cardiomyopathy.

Am J Emerg Med 2018 Dec 10. Epub 2018 Dec 10.

Emergency and Critical Care Center, Kurashiki Central Hospital, Japan.

Heart failure typically manifests with exertional dyspnea or limb edema. Old age, underlying heart disease, and coronary risk factors are known risk factors for heart failure. Thus, congestive heart failure is rarely considered as a differential diagnosis of chronic cough in a previously healthy young person. Read More

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December 2018

Computational fluid dynamics analysis of H-uvulopalatopharyngoplasty in obstructive sleep apnea syndrome.

Am J Otolaryngol 2018 Dec 6. Epub 2018 Dec 6.

The Department of Otolaryngology-Head and Neck Surgery, The First Hospital of Jilin University, Changchun, 130000, Jilin Province, China. Electronic address:

Purpose: To explore the impact of H-uvulopalatopharyngoplasty (H-UPPP) in obstructive sleep apnea syndrome (OSAS) and gain insights into the potential mechanism underlying improvement by H-UPPP.

Methods: In a cohort of 11 OSAS patients, computational fluid dynamics (CFD) models of the upper airway were obtained using commercial software from computed tomography (CT) datasets before and after H-UPPP. Morphological and numerical parameters were respectively computed and compared during the peak tidal inspiratory flow. Read More

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December 2018

Clinical Cybersecurity Training Through Novel High-Fidelity Simulations.

J Emerg Med 2018 Dec 12. Epub 2018 Dec 12.

Department of Anesthesia and Pain Medicine, University of California Davis, Davis, California.

Background: Cybersecurity risks in health care systems have traditionally been measured in data breaches of protected health information, but compromised medical devices and critical medical infrastructure present risks of disruptions to patient care. The ubiquitous prevalence of connected medical devices and systems may be associated with an increase in these risks.

Objective: This article details the development and execution of three novel high-fidelity clinical simulations designed to teach clinicians to recognize, treat, and prevent patient harm from vulnerable medical devices. Read More

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December 2018

Amyloid Cardiomyopathy in the Emergency Department.

J Emerg Med 2018 Dec 12. Epub 2018 Dec 12.

Department of Emergency Medicine, Mount Sinai Medical Center, Miami Beach, Florida; Emergency Department Ultrasonography, Mount Sinai Medical Center, Miami Beach, Florida.

Background: Cardiac amyloidosis is an underdiagnosed cause of restrictive cardiomyopathy resulting from the infiltration of the myocardium by amyloid proteins.

Case Report: We report the case of an 83-year-old woman who presented with increasing dyspnea and lower-extremity swelling. She reported a medical history of unspecified heart failure. Read More

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December 2018
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Surgical repair of aortic aneurysms and reduced incidence of dementia.

Int J Cardiol 2018 Dec 7. Epub 2018 Dec 7.

Department of Emergency Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan; Department of Physiology and Biophysics, Graduate Institute of Physiology, National Defense Medical Center, Taipei, Taiwan.. Electronic address:

Background: Dementia and aortic aneurysms share clinical risk factors and molecular signaling pathways. However, the association between dementia and aortic aneurysms has not been examined. The potential effects of open surgical repair (OSR) of aortic aneurysms on future dementia events are unknown. Read More

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December 2018

Assessment of confined space entry and rescue training for aircraft rescue and fire fighting (ARFF) members in the United States.

J Safety Res 2018 Dec 5;67:77-82. Epub 2018 Oct 5.

Embry-Riddle Aeronautical University, Worldwide Campus College of Aeronautics, Department of Aeronautics Graduate Studies, Daytona Beach, FL, USA.

Introduction: Fire and emergency service workers, including Aircraft Rescue and Fire Fighting members, may be called on to perform confined space entry and rescue operations. The purpose of the present study was to develop a comprehensive and valid understanding of the present state of confined space entry and rescue training effectiveness and resultant compliance or use of best practices among trained Aircraft Rescue and Fire Fighting personnel.

Method: The study used a convergent, parallel mixed-methods approach. Read More

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December 2018

Calculating the economic burden of fatal drowning in Australia.

J Safety Res 2018 Dec 21;67:57-63. Epub 2018 Sep 21.

Royal Life Saving Society - Australia, Broadway, NSW, Australia.

Background: Aquatic activities provide physical and social benefits, while the risk of drowning generates countervailing social costs. Drawing on estimates of fatal drowning gathered by Royal Life Saving Society - Australia, this paper outlines a method for estimating the economic burden attributable to fatal drowning.

Methods: This study estimated the burden of fatal drowning by combining Value of a Statistical Life Year (VSLY), hospitalization, productivity and emergency services costs. Read More

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December 2018

Discharge materials provided to patients with kidney stones in the emergency department may be a source of misinformation.

Can J Urol 2018 Dec;25(6):9585-9590

University of Vermont Medical Center, Burlington, Vermont, USA.

Introduction: Renal colic is commonly seen in the emergency department (ED), where the focus is on diagnosis and symptom control. Educational materials are sometimes provided upon discharge, however, no standard content has been established. We characterized the educational materials given to patients reporting to EDs in different regions across the U. Read More

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December 2018

Predictors of self-harm emergency department visits in adolescents: A statewide longitudinal study.

Gen Hosp Psychiatry 2018 Dec 8;56:28-35. Epub 2018 Dec 8.

Violence Prevention Research Program, University of California, Davis, Sacramento, CA 95817, USA. Electronic address:

Objective: This study investigated patient- and area-level characteristics associated with adolescent emergency department (ED) patients' risk of subsequent ED visits for self-harm.

Method: Retrospective analysis of adolescent patients presenting to a California ED in 2010 (n = 480,706) was conducted using statewide, all-payer, individually linkable administrative data. We examined associations between multiple predictors of interest (patient sociodemographic factors, prior ED utilization, and residential mobility; and area-level characteristics) and odds of a self-harm ED visit in 2010. Read More

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December 2018

Medical populism.

Soc Sci Med 2018 Dec 7;221:1-8. Epub 2018 Dec 7.

University of Canberra, Australia. Electronic address:

Medical emergencies are staple features of today's 24/7 culture of breaking news. As politics becomes increasingly stylised, audiences fragmented, and established knowledge claims contested, health crises have become even more vulnerable to politicisation. We offer the vocabulary of medical populism to make sense of this phenomenon. Read More

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December 2018
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An Isolated Ureteropelvic Junction Injury Following a Low-Impact Mechanical Fall.

Urology 2018 Dec 12. Epub 2018 Dec 12.

University of Massachusetts Memorial Health Care.

Objective: To describe the presentation of a rare isolated ureteropelvic junction injury resulting from a mechanical fall on ice.

Materials And Methods: A 71-year-old previously healthy man presented to the emergency department at the University of Massachusetts Medical School three hours following falling on ice with complaints of gross hematuria and flank pain. Patient records were accessed via the institution's electronic medical records system between March 22, 2018 and April 22, 2018. Read More

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December 2018

Inhibition of SIRT1 by microRNA-9, the key point in process of LPS-induced severe inflammation.

Arch Biochem Biophys 2018 Dec 12. Epub 2018 Dec 12.

Department of Burns and Cutaneous Surgery, Xijing Hospital, The Fourth Military Medical University, 127 Changle West Road, Xi'an, Shaanxi, 710032, China. Electronic address:

Severe inflammation may lead to multiple organs dysfunction syndrome, which has a high mortality. MicroRNA is found participated in this process. In this study we developed a lipopolysaccharide-induced inflammation cell model on macrophages and a lipopolysaccharide-induced inflammation mouse model. Read More

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December 2018
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Acute schizophrenia-like psychosis as major clinical presentation of Graves’ disease successfully treated by radioiodine in combination with antipsychotics: a case report.

Actas Esp Psiquiatr 2018 Nov 1;46(6):242-8. Epub 2018 Nov 1.

Department of Nuclear Medicine, China-Japan Union Hospital of Jilin University, Changchun, Jilin, P.R. China.

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November 2018
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Nurses' descriptions of person-centred care for older people in an acute medical ward - on the individual, team and organizational levels'.

J Clin Nurs 2018 Dec 15. Epub 2018 Dec 15.

School of Nursing and Midwifery l College of Science, Health and Engineering, Latrobe University Melbourne, Victoria, Australia, 3086.

Aim And Objectives: To describe nurses' experiences of providing person-centred care (PCC) for older people on an acute medical ward.

Background: There is evidence that PCC for older people contributes to a higher quality care and increased satisfaction with care. However there is a shortness of studies providing concrete examples of what facilitates nurses providing PCC for older people in acute care. Read More

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December 2018

Achieving proficiency in rigid bronchoscopy-a study in manikins.

Ir J Med Sci 2018 Dec 14. Epub 2018 Dec 14.

Department of Anaesthesia, The Rotunda Hospital, Parnell Square, Dublin, Ireland.

Background: Rigid bronchoscopy may be used to relieve acute airway obstruction following induction of anaesthesia and is a recommended option for management of the difficult airway. The ability of anaesthetists to perform rigid bronchoscopy has not been reported. We sought to explore the acquisition of procedural skill in rigid bronchoscopy by anaesthesiologists in a manikin. Read More

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December 2018

Pitfalls in the triage and evaluation of patients with suspected acute ethanol intoxication in an emergency department.

Intern Emerg Med 2018 Dec 14. Epub 2018 Dec 14.

Division of Emergency Medicine, Department of Community Medicine, Primary Care and Emergency Medicine, Geneva University Hospitals and Geneva University, Faculty of Medicine, Geneva, Switzerland.

Acute ethanol intoxication (AEI) is frequent in emergency departments (EDs). These patients are at risk of mistriage, and to leave the ED without being seen. This study's objective was to describe the process and performance of triage and trajectory for patients with suspected AEI. Read More

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December 2018

The Impact of the Patient-Centered Medical Home on Asthma-Related Visits to the Emergency Room: A Fixed Effects Regression Approach.

Matern Child Health J 2018 Dec 14. Epub 2018 Dec 14.

Department of Health Policy and Administration, Pennsylvania State University, 601A Donald H. Ford Building, University Park, PA, 16802, USA.

Objective To estimate the effect of a patient-centered medical home (PCMH) intervention on asthma-related emergency room (ER) visits of pediatric patients. Methods Patients receiving care at pediatric primary care practices participating in the Florida Pediatric Medical Home Demonstration Project as well as pediatric patients treated at non-participating clinics were identified from 4 years of claims and enrollment data. We estimate several fixed effects logistic regression models using one pre-treatment year and three post-treatment years to investigate whether asthma-related ER visits decreased because of the PCMH intervention. Read More

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December 2018

Imaging in neurointerventional stroke treatment: review of the recent trials and what your neurointerventionalist wants to know from emergency radiologists.

Emerg Radiol 2018 Dec 14. Epub 2018 Dec 14.

Department of Radiology and Biomedical Imaging, University of California San Francisco School of Medicine, 550 16th. Street, San Francisco, CA, 94158, USA.

Stroke is one of the leading causes of death and disability worldwide. Standard treatment for stroke is intravenous (IV) injection of tissue plasminogen activator (t-PA) rapidly after symptom onset. However, there are limitations of IV t-PA treatment, such as a short time window for administration and risk for hemorrhage. Read More

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December 2018

Evaluation of new quality indicators for the TraumaRegister DGU using the systematic QUALIFY methodology.

Eur J Trauma Emerg Surg 2018 Dec 14. Epub 2018 Dec 14.

Department for Anesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Therapy, Armed Forces Hospital Ulm, HEMS "Christoph 22", Oberer Eselsberg 40, 89081, Ulm, Germany.

Background: The TraumaRegister DGU (TR-DGU) of the German Trauma Society (Deutsche Gesellschaft für Unfallchirurgie, DGU) enables the participating hospitals to perform quality management. For that purpose, nine so-called audit filters have existed, since its foundation, which, inter alia, is listed in the Annual Report. The objective of this study effort is a revision of these quality indicators with the aim of developing pertinent new and reliable quality indicators for the management of severely injured patients. Read More

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December 2018
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The role of recessive inheritance in early-onset epileptic encephalopathies: a combined whole-exome sequencing and copy number study.

Eur J Hum Genet 2018 Dec 14. Epub 2018 Dec 14.

Institute of Medical Genetics, University of Zurich, Schlieren-Zurich, 8952, Switzerland.

Early-onset epileptic encephalopathy (EE) and combined developmental and epileptic encephalopathies (DEE) are clinically and genetically heterogeneous severely devastating conditions. Recent studies emphasized de novo variants as major underlying cause suggesting a generally low-recurrence risk. In order to better understand the full genetic landscape of EE and DEE, we performed high-resolution chromosomal microarray analysis in combination with whole-exome sequencing in 63 deeply phenotyped independent patients. Read More

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December 2018

Dexamethasone versus prednisone for children receiving asthma treatment in the paediatric inpatient population: protocol for a feasibility randomised controlled trial.

BMJ Open 2018 Dec 14;8(12):e025630. Epub 2018 Dec 14.

Departments of Pediatrics and Emergency Medicine, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Canada.

Introduction: Asthma exacerbations are a leading cause of paediatric hospitalisations. Corticosteroids are key in the treatment of asthma exacerbations. Most current corticosteroids treatment regimens for children admitted with asthma exacerbation consist of a 5-day course of prednisone or prednisolone. Read More

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December 2018

Comparison of the validity of checklist assessment in cardiac arrest simulations with an app in an academic hospital in Taiwan: a retrospective observational study.

BMJ Open 2018 Dec 14;8(12):e024309. Epub 2018 Dec 14.

Emergency Department, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, Taiwan.

Introduction: Robust assessment is a crucial component in Advanced Cardiac Life Support (ACLS) training to determine whether participants have achieved learning objectives with little or no variation in their overall outcomes. This study aimed to evaluate resuscitation performance by real-time logs. We hypothesised that instructors may not be able to evaluate time-sensitive parameters, namely, chest compression fraction, time to initiating chest compression and time to initiating defibrillation accurately in a subjective manner. Read More

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December 2018

Prognostic value of Modified Early Warning Score generated in a Chinese emergency department: a prospective cohort study.

BMJ Open 2018 Dec 14;8(12):e024120. Epub 2018 Dec 14.

Research Institute of Gynecology and Obstetrics, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Objectives: This study aimed to validate the performance of the Modified Early Warning Score (MEWS) in a Chinese emergency department and to determine the best cut-off value for in-hospital mortality prediction.

Design: A prospective, single-centred observational cohort study.

Setting: This study was conducted at a tertiary hospital in South China. Read More

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December 2018

Disability and morbidity among older patients in the emergency department: a Danish population-based cohort study.

BMJ Open 2018 Dec 14;8(12):e023803. Epub 2018 Dec 14.

Department of Geriatric Medicine, Odense University Hospital, Odense, Denmark.

Objectives: The objective was to describe the prevalence of geriatric conditions among older medical patients in the emergency department (ED) and the association with admission, mortality, reattendance and loss of independency.

Design: Population-based prospective cohort study.

Setting: ED of a large university hospital. Read More

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December 2018

Study protocol for a randomised controlled trial of humanoid robot-based distraction for venipuncture pain in children.

BMJ Open 2018 Dec 14;8(12):e023366. Epub 2018 Dec 14.

Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.

Introduction: Intravenous insertion (IVI) is a very common procedure in the emergency department (ED). IVI is often painful and stressful for both children and their families. Currently, distraction therapy is not used as a standard of care for IVI in North America. Read More

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December 2018
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Costs and outcomes in evaluating management of unhealed surgical wounds in the community in clinical practice in the UK: a cohort study.

BMJ Open 2018 Dec 14;8(12):e022591. Epub 2018 Dec 14.

Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK.

Objective: To evaluate the patient pathways and associated health outcomes, resource use and corresponding costs attributable to managing unhealed surgical wounds in clinical practice, from initial presentation in the community in the UK.

Methods: This was a retrospective cohort analysis of the records of 707 patients in The Health Improvement Network (THIN) database whose wound failed to heal within 4 weeks of their surgery. Patients' characteristics, wound-related health outcomes and healthcare resource use were quantified, and the total National Health Service (NHS) cost of patient management was estimated at 2015/2016 prices. Read More

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December 2018

Ten-year trends in traumatic brain injury: a retrospective cohort study of California emergency department and hospital revisits and readmissions.

BMJ Open 2018 Dec 14;8(12):e022297. Epub 2018 Dec 14.

Department of Neurological Surgery, University of California, San Francisco, San Francisco, California, USA.

Objective: To describe visits and visit rates of adults presenting to emergency departments (EDs) with a diagnosis of traumatic brain injury (TBI). TBI is a major cause of death and disability in the USA; yet, current literature is limited because few studies examine longer-term ED revisits and hospital readmission patterns of TBI patients across a broad spectrum of injury severity, which can help inform potential unmet healthcare needs.

Design: We performed a retrospective cohort study. Read More

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December 2018

Emergency Room Safer Transfer of Patients (ER-STOP): a quality improvement initiative at a community-based hospital to improve the safety of emergency room patient handovers.

BMJ Open 2018 Dec 14;8(12):e019553. Epub 2018 Dec 14.

Department of Medicine, Division of Respirology, University of Toronto and Michael Garron Hospital, Michael Garron Hospital, Toronto, Ontario, Canada.

Objectives: Ensure early identification and timely management of patient deterioration as essential components of safe effective healthcare. Prompted by analyses of incident reports and deterioration events, a multicomponent organisational rescue from danger system was redesigned to decrease unexpected inpatient deterioration.

Design: Quality improvement before-after unblinded trial. Read More

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December 2018

Is hepatitis A virus infection under control? lessons in the application of viral sequencing for the development of vaccination schemes in emergency situations.

Authors:
Nora A Fierro

EBioMedicine 2018 Dec 11. Epub 2018 Dec 11.

Unidad de Inmunovirologia, Servicio de Biologia Molecular en Medicina, Hospital Civil de Guadalajara ″Fray Antonio Alcalde″, Mexico; Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Mexico. Electronic address:

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December 2018

Disparities in Inter-hospital Helicopter Transportation for Hispanics by Geographic Region: A Threat to Fairness in the Era of Thrombectomy.

J Stroke Cerebrovasc Dis 2018 Dec 11. Epub 2018 Dec 11.

Department of Neurology, University of Iowa, Iowa City, Iowa; Department of Neurosurgery, University of Iowa, Iowa City, Iowa; Department of Epidemiology, University of Iowa, Iowa City, Iowa. Electronic address:

Background And Purpose: Mechanical thrombectomy (MT) is a time-dependent therapy that is only available at a limited number of hospitals. As such, patients that live at a considerable distance of those specialized centers often require rapid interhospital emergent evacuation with Helicopter Emergency Medical Services (HEMS) to be considered for MT. It is not known whether the use of HEMS is equitable across different groups of patients. Read More

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December 2018
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The use of cadaver models to diagnose rib fractures: A pilot study.

Am J Emerg Med 2018 Nov 16. Epub 2018 Nov 16.

Department of Emergency Medicine, Staten Island University Hospital, Northwell Health, Staten Island, NY, United States of America.

Background: In the emergency department, rib fractures are a common finding in patients who sustain chest trauma. Rib fractures may be a sign of significant, underlying pathology, especially in the elderly patients where rib fractures are associated with significant morbidity and mortality. To date, no studies have evaluated the ability of ultrasound to detect rib fractures using cadaver models and subsequently use this model as a teaching tool. Read More

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November 2018

Clinical characteristics of ER patients reporting synthetic cannabinoid use.

Am J Emerg Med 2018 Dec 6. Epub 2018 Dec 6.

Department of Emergency Medicine, University of Louisville School of Medicine, United States of America. Electronic address:

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December 2018

Therapeutic effect of ultrasound interventional perirenal catheter-assisted early peripancreatic lavage of protease inhibitor on severe acute pancreatitis in miniature pigs.

Pancreatology 2018 Dec 5. Epub 2018 Dec 5.

Department of Emergency, First Medical Center, General Hospital of the PLA, Haidian district, Beijing, 100853, China. Electronic address:

Objectives: To study the therapeutic effect of early peripancreatic lavage of ulinastatin on severe acute pancreatitis(SAP).

Methods: Sixteen pigs were divided into 4 groups: model(SAP), saline lavage(SL), ulinastatin lavage(UL), intravenous ulinastatin(IU). UL and SL group were given peripancreatic lavage of ulinastatin by ultrasound-guided perirenal catheterization and IU group was intravenously instilled with ulinastatin. Read More

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December 2018

The Results of Randomized Controlled Trials in Emergency Medicine Are Frequently Fragile.

Ann Emerg Med 2018 Dec 12. Epub 2018 Dec 12.

Oklahoma State University Center for Health Sciences, Tulsa, OK.

Study Objective: Randomized controlled trials govern evidence-based clinical practice, and it is therefore critical that their results be robust. We aim to investigate the fragility of randomized controlled trials in emergency medicine by determining how often significance would be nullified with small changes in outcomes using the fragility index.

Methods: We conducted a methodological systematic review of randomized controlled trials in emergency medicine published in the top 10 general medicine journals and the top 10 emergency medicine journals. Read More

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December 2018

Screening, Brief Intervention, and Referral to Treatment by Emergency Nurses: A Review of the Literature.

J Emerg Nurs 2018 Dec 11. Epub 2018 Dec 11.

Introduction: Emergency nurses could assume a unique role in the screening process and provide patient education regarding the consequences of harmful alcohol use. Screening, brief intervention, and referral to treatment is an evidence-based method used to identify drinking behaviors that may have a negative impact on people's lives and reduce abuse or dependence on alcohol.

Methods: A systematic review of the literature was conducted to evaluate both the effectiveness as well as the feasibility of nurse implementation of screening, brief intervention, and referral to treatment in the ED setting. Read More

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December 2018

Evaluation of a Practice Improvement Protocol for Patient Transfer From the Emergency Department to the Surgical Intensive Care Unit After a Level I Trauma Activation.

J Emerg Nurs 2018 Dec 11. Epub 2018 Dec 11.

Background: ED boarding is a major issue in many hospitals. ED boarding occurs when there is insufficient hospital capacity to supply inpatient beds for admitted patients. ED boarding is not only a problem because of increased wait times for patients but also because it results in delays in administration of medication, higher rates of complications, and increased mortality. Read More

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December 2018
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A Lateral Neck Myeloid Sarcoma Presenting as Acute Otitis Externa.

Arch Iran Med 2018 Nov 1;21(11):544-546. Epub 2018 Nov 1.

Iranian Research Center for HIV/AIDS (IRCHA), Tehran University of Medical Sciences, Tehran, Iran.

Myeloid sarcoma (MS) is a solid extra-medullary tumor of immature myeloid cells which could occur before, during or after remission of acute leukemia at any site on the body. Owing to variation in differential diagnosis, pathologic evaluation and immunohistochemical staining are essential for definitive diagnosis. Rarely, MS has been shown as an isolated extramedullary relapse (iEMR) after allogeneic stem cell transplantation (allo-SCT), which often does not necessarily result in bone marrow involvement. Read More

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November 2018

An Approach Towards Reducing Road Traffic Injuries and Improving Public Health Through Big Data Telematics: A Randomised Controlled Trial Protocol.

Arch Iran Med 2018 Nov 1;21(11):495-501. Epub 2018 Nov 1.

Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

Objective: Deaths due to road traffic accidents (RTAs) are a major public health concern around the world. Developing countries are over-represented in these statistics. Punitive measures are traditionally employed to lower RTA related behavioural risk factors. Read More

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November 2018
1 Read