Search Our Scientific Publications & Authors

Auris Nasus Larynx 2022 Apr 17. Epub 2022 Apr 17.

Department of Otorhinolaryngology, Juntendo University Faculty of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo, 113-8421 Japan.

Creutzfeldt-Jakob disease is a fatal transmissible prion disease of the central nervous system. Dizziness as an initial manifestation of Creutzfeldt-Jakob disease is rare. However, patients with Creutzfeldt-Jakob disease and dizziness may initially visit the otolaryngology department, but this is uncommon. Read More

Int J Audiol 2022 Apr 19:1-7. Epub 2022 Apr 19.

Faculty of Medicine, Department of Otolaryngology and Head and Neck Surgery, Semmelweis University, Budapest, Hungary.

Objective: To compare the diagnostic accuracies of air caloric testing with electronystagmography and the vHIT (video-head impulse test).

Design: Prospective, controlled study.

Study Sample: MD (Ménière's disease), 26; vestibular neuritis, 27; control, 56. Read More

Children (Basel) 2021 Dec 27;9(1). Epub 2021 Dec 27.

Audiology, Primary Care Department, Via del Pozzo 69, 41100 Modena, Italy.

Vestibular migraine (VM) is the most common cause of episodic vertigo in children. Vertigo, nausea, dizziness and unsteadiness are often complained of by children with migraine, which can precede, follow or be present simultaneously with headache. The aim of this study was to use posturography to investigate the visually evoked postural responses (VEPRs) of children with VM and compare them to data obtained from children with primary headache (M) and controls (C). Read More

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2021 Dec 9. Epub 2021 Dec 9.

Department of Otorhinolaryngology, Head and Neck Surgery, First Faculty of Medicine, Charles University in Prague and University Hospital Motol, V Uvalu 84, 150 06, Prague 5, Czech Republic.

Objectives: Hearing preservation after vestibular schwannoma (VS) surgery remains a surgical challenge. In some patients with preserved inner ear function, hearing improvement is achievable. As it is currently impossible to determine which patients will present this outcome, predictions must rely on previously published reports. Read More

Auris Nasus Larynx 2022 Aug 19;49(4):571-576. Epub 2021 Nov 19.

Department of Otorhinolaryngology & Head and Neck Surgery, Tokyo Medical University.

Objective: To analyze the preoperative patterns of caloric test, eye tracking test (ETT), and optokinetic pattern (OKP) in patients with acoustic neuroma (AN) and compare them with the postoperative patterns of ETT and OKP results METHODS: A total of 166 patients with AN (102 women; mean age: 41 years, range: 11-79 years) who were being treated at our hospital between 2013 and 2016 were enrolled. Preoperatively, a detailed history was taken regarding the presence of subjective symptoms of equilibrium dysfunction, and the patients underwent caloric test, ETT, and OKP. They were classified into three groups based on the preoperative ETT and OKP results as follows: Group A, normal ETT and OKP; Group B, either ETT or OKP was abnormal; and Group C, both ETT and OKP were abnormal. Read More

Am J Otolaryngol 2022 Jan-Feb;43(1):103171. Epub 2021 Aug 6.

First Physicians Group Silverstein Institute, 1901 Floyd Street, Sarasota, FL 34239, United States; Ear Research Foundation, 1901 Floyd Street, Sarasota, FL 34239, United States.

Purpose: Cochlear implantation (CI) has been shown to reduce vestibular function postoperatively in the implanted ear. The objective of this study was to identify the prevalence of preoperative vestibular weakness in CI candidates and identify any risk factors for postoperative dizziness.

Study Design: Retrospective cohort study. Read More

Laryngoscope 2022 04 16;132(4):873-880. Epub 2021 Aug 16.

Department of Otolaryngology-Head and Neck Surgery, University Hospitals Case Medical Center, Cleveland, Ohio, U.S.A.

Objective: Enlarged vestibular aqueduct (EVA) is a congenital condition that can lead to various outcomes in pediatric patients including hearing loss and vestibular dysfunction. Our goal was to critically appraise the literature on the proportion of patients with EVA who report vestibular dysfunction, determine relevant risk factors for the development of these symptoms, and describe vestibular tests and interventions used to improve outcomes.

Methods: A systematic review was performed in accordance with the PRISMA guidelines. Read More

J Basic Clin Physiol Pharmacol 2021 Jul 20. Epub 2021 Jul 20.

Department of Otolaryngology-Head & Neck Surgery, Hadassah Hebrew-University Medical Centre, Jerusalem, Israel.

Objectives: Idiopathic sudden sensorineural hearing loss (SSNHL) represents a frequently encountered otological entity, of various types and severity, with an array of associated symptoms including vertigo. This is a devastating life-changing condition with a blurry prognosis. The objective of this study was to determine the clinical association of vestibular impairment by electronystagmography (ENG) and caloric tests, and their ability to predict prognosis. Read More

Phys Ther 2021 10;101(10)

Department of Physical Therapy, Laboratory of Pediatric Studies (LEPed), Universidade Federal de Pernambuco (UFPE), Recife, Pernambuco, Brazil.

Objective: The purpose of this study was to assess the static balance of children with sensorineural hearing loss (SNHL) according to the degrees of SNHL and the function of the vestibular system.

Methods: This cross-sectional study was conducted in public schools located in Caruaru, Pernambuco state, Brazil, with 130 children (65 with normal hearing and 65 with SNHL as documented by air and bone conduction audiometry) of both sexes between 7 and 11 years old. Static balance was assessed by a stabilometric analysis using a force platform consisting of the circular area of center-of-pressure displacement of the children evaluated in 3 positions: bipedal support with feet together and parallel (PF), tandem feet (TF), and 1 foot (OF), carried out under 2 sensory conditions each, with eyes open and eyes closed. Read More

J Clin Med 2021 Jun 25;10(13). Epub 2021 Jun 25.

ENT Department, Faculty of Medicine, Jagiellonian University Medical College, 30-688 Krakow, Poland.

Objectives: The aim of the study was to evaluate the frequency of vertigo symptoms and potential labyrinth damage in patients with diagnosed Lyme disease (LD). LD can affect the vestibulocochlear nerve, leading to hearing loss and vertigo/dizziness.

Material And Methods: The study included a group of 38 patients between the ages of 20 and 77, who were hospitalized due to vertigo/dizziness between 2018 and 2019. Read More

Ear Hear 2021 Sep/Oct;42(5):1119-1126

Department of Translational Neurosciences, University of Antwerp, Antwerp, Belgium.

Importance: Given the rising prevalence of patients with dementia and those at risk for it, early identification is prioritized. As vestibular dysfunction is associated with Alzheimer's disease (AD) and may contribute to its onset, vestibular assessment may yield an opportunity in early dementia screening.

Objective: This systematic review structures and compares the different raw outcome measures used to assess vestibular function while comparing older adults with preserved cognition to individuals with cognitive impairment, either suffering from mild cognitive impairment (MCI) or AD. Read More

Curr Alzheimer Res 2021 Mar 23. Epub 2021 Mar 23.

Department of Neurology, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki. Japan.

Background: In a previous study on Alzheimer's disease (AD), we showed that vestibular dysfunction derived from cerebral disorders contributes to balance disorders. No previous clinical study has attempted to prevent the progression of balance disorders in dementia patients through vestibular stimulation using an air caloric device.

Objective: The purpose of this pilot study was to delay the progression of balance disorders by inducing vestibular compensation, specifically by utilizing the effect of vestibular stimulation to activate the cerebrum. Read More

Am J Otolaryngol 2021 May-Jun;42(3):102909. Epub 2021 Jan 12.

Department of Neurosciences DNS, Otolaryngology Section, Padova University, Padova, Italy. Electronic address:

Purpose: Whiplash injury is a frequent traumatic lesion occurring mainly in road accidents, which may also cause dizziness severe enough to impact everyday life. Vestibular examination is routinely performed on these patients, although the role of the neuro-otologist is still not clearly defined. The main endpoint of this study was to describe the videonystagmography (VNG) evidence in a large cohort of patients who underwent road traffic whiplash injury. Read More

Ir J Med Sci 2021 Nov 12;190(4):1571-1575. Epub 2021 Jan 12.

Department of Family Medicine, Cumming School of Medicine, University of Calgary, Calgary, Canada.

Objective: To assess the long-term stability of caloric testing in patients.

Methods: In this retrospective study, Cronbach's alpha was used to determine whether caloric testing results are stable over time (up to 7 years) in patients who have not undergone interventions. After excluding invalid records, two hundred patients who underwent repeated caloric testing in the same lab over varying periods of time were included. Read More

Ann Otol Rhinol Laryngol 2021 Jul 30;130(7):718-723. Epub 2020 Oct 30.

Department of Otolaryngology - Head & Neck Surgery, Albany Medical Center, Albany, NY, USA.

Objective: Videonystagmography (VNG) is a commonly ordered test to evaluate patients with vestibular complaints. To date, there are no evidence-based guidelines for evaluating patients presenting with vestibular symptoms. This study evaluates the cost effectiveness of VNG and the impact of VNG findings on patient management. Read More

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2020 Aug;55(8):754-759

Department of Otorhinolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.

To explore the possible pathogenesis of central paroxysmal positional vertigo (CPPV) by analyzing its clinical manifestations and characteristics. The clinical data of 3 patients with CPPV, including 1 male and 2 females, aged 36, 14 and 70 years old respectively, were collected from the Department of Otorhinolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences from June 2014 to June 2018. The clinical symptoms, nystagmus, other central ocular motor abnormalities, MRI, PET-CT, and laboratory findings were analyzed retrospectively. Read More

Intern Med 2020 Dec 12;59(24):3229-3233. Epub 2020 Aug 12.

Department of Neurology, Japanese Red Cross Akita Hospital, Japan.

A 38-year-old man presented with primary position upbeat nystagmus accompanied by peripheral neuropathy. The serum vitamin B12 level was low along with high plasma homocysteine level, indicating vitamin B12 deficiency. Cyanocobalamin supplementation showed partial clinical and electrophysiological improvement. Read More

Brain Behav 2020 09 20;10(9):e01695. Epub 2020 Jul 20.

Department of Otolaryngology, Head and Neck Surgery, Wroclaw Medical University, Wroclaw, Poland.

Introduction: Vertigo and balance disorders are a significant clinical problem, especially in elderly patients. The narrowing of cranial vessels may be asymptomatic or produce neurological symptoms. Very often nonspecific signs of ischemia occur, such as headache, vertigo, or dizziness. Read More

Am J Otolaryngol 2020 Jul - Aug;41(4):102497. Epub 2020 Apr 19.

Department of Neuroscience DNS, Otolaryngology Section, Padova University, Padova, Italy. Electronic address:

Purpose: Whiplash is a type of trauma typically caused by a rear end collision in a road accident. About one in two patients who experience whiplash report dizziness and balance problems, which can severely affect their activities in daily life. In industrialized countries, the number of elderly people with a driving license has increased in recent years. Read More

Acta Otolaryngol 2020 Aug 24;140(8):639-645. Epub 2020 Apr 24.

Otoneurology Unit, ENT Department, Hospital "La Fe", Valencia, Spain.

Generally, vertical component of the skull vibratory nystagmus (VCN) is ignored in the clinical practise. Thus, the relative contribution of the vestibular organs in the presence of VCN remains unknown. To determine the association between vertical semicircular canal (vSCC) function and the presence of VCN. Read More

Rinsho Shinkeigaku 2020 May 18;60(5):346-350. Epub 2020 Apr 18.

Department of Neurology, Dokkyo Medical University.

A 68-year-old woman was referred to our hospital for progressive dizziness, gait disturbances and weight loss for 18 months. The patient was alert and showed dysphagia and a marked tendency to fall backward. Electronystagmography showed bilateral vestibular dysfunction and audiometry showed right sensorineural hearing disturbance. Read More

Auris Nasus Larynx 2020 Dec 5;47(6):1070-1073. Epub 2020 Apr 5.

Department of Otolaryngology, Toho University Sakura Medical Center, Sakura City, Chiba 285-0841, Japan. Electronic address:

Major earthquakes occasionally cause vertiginous attacks or persistent dizziness, which may be related to the effects of autonomic stress on equilibrium function and/or psychological factors. We present the case of a 73-year-old woman who suffered from persistent dizziness for 1 year, during which she lived in a house tilted by the great 2011 Tōhoku earthquake. An electronystagmogram demonstrated leftward horizontal and downbeat nystagmus in the sitting and supine positions with eyes closed. Read More

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2020 Feb;34(2):186-189

Vertical nystagmus is a vertical nystagmus caused by structural abnormalities and/or dysfunction of the central vestibular system and observed in situ in the center of the eyeball. There are two kinds of nystagmus （UBN） and downbeat nystagmus （DBN） according to the direction of nystagmus. The diagnosis of UBN is mainly made by naked eye or electronystagmography/viewer. Read More

J Otolaryngol Head Neck Surg 2020 Feb 5;49(1). Epub 2020 Feb 5.

Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA, 02115, USA.

Background: Vestibular symptoms such as vertigo and imbalance are known to occur in some cochlear implant patients during the immediate postoperative period; however, acute vertigo in implanted children occurring remotely from the postoperative period has not been previously well-described.

Case Presentation: A three-year-old girl with a history of bilateral sequential cochlear implantation presented with acute labyrinthitis associated with sudden onset of vertigo, balance impairment, and decline in right cochlear implant function 2 years after her most recent implant surgery. We describe her audiological and vestibular testing results during both the acute phase and following medical management and recovery. Read More

Front Neurol 2019 10;10:1341. Epub 2020 Jan 10.

Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, Antwerp, Belgium.

Radiologic abnormalities on computed tomography (CT), including narrowing or sclerosis of the semicircular canals (SCCs), and T2-weighted magnetic resonance imaging (MRI), including signal loss in the SCC, have been reported as potential biomarkers in patients with P51S mutations in the gene (i.e., DFNA9). Read More

Endocrine 2020 03 4;67(3):659-664. Epub 2020 Jan 4.

Laboratory of Motor Control and Body Balance, Center for Health Science Research, Federal University of Sergipe, Sergipe, 49060-100, Brazil.

Purpose: Body balance involves the vestibular, visual, and proprioceptive systems. IGF-I is a GH-dependent key factor in the development and postnatal differentiation of the inner ear in mice and men, but its role in the vestibular function in adult humans is unknown. We have previously described a cohort of individuals with severe isolated GH deficiency (IGHD) caused by a mutation in the GHRH receptor (GHRHR) gene. Read More

Strabismus 2020 03 31;28(1):3-6. Epub 2019 Dec 31.

Children's Eye Disease and Ocular Motility Institute of Purui Jina, Shandong Purui Liangkang Eye Hospital, Jinan, Shandong Province, P. R. China.

: To establish a relation between pendular low amplitude high frequency (PLAHF) components and congenital retinal disorders.: Patients who showed PLAHF components in their eye-movement recording between January 2016 to January 2019 were included. Best corrected visual acuity (BCVA), refraction, strabismus assessment, fundus photograph, spectral domain-optical coherence tomography (SD-OCT), full-field electroretinography (f-ERG), clinical ophthalmological examination, and gene tests were used to determine their clinical conditions, especially their retina conditions in all patients. Read More

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2020 Dec 3;164(4):444-453. Epub 2019 Dec 3.

Department of Neurology, 2.

Aims: Preoperative chemical vestibular ablation can reduce vestibular symptoms in patients who have gone through vestibular schwannoma resection. The goal of this study was to determine whether chemical vestibular prehabituation influences the patients' post-operative perception of visual stimulation, mental status and quality of life. We also tried to find out whether increases of optokinetic nystagmus, measured by routine electronystagmography, correlate with subjective symptoms. Read More

Indian J Otolaryngol Head Neck Surg 2019 Dec 18;71(4):453-463. Epub 2019 Feb 18.

Present Address: Department of Otorhinolaryngology, Nepalgunj Medical College, Nepalgunj, Nepal.

The central pathologies present with perverted auditory perception and compromised postural control. Considering the existing controversy this study involves assessments of 100 cases of post fossa tumefactions in which a detailed clinical and neuro-otological (pure tone audiometry, electronystagmography, brainstem evoked response audiometry) profile is compared with their imaging patterns. The CP angle schwannomas (N = 26) presented with abnormal speech tests (N = 18), abnormal auditory adaptation (N = 7) and ABR with pathologically increased latency of wave V (N = 32), poor formation of wave I (N = 31) along with abnormal inter-wave interval (N = 32). Read More