14,767 results match your criteria Electroconvulsive Therapy


Acute Phase Treatment Outcomes of Electroconvulsive Therapy in Adolescents and Young Adults.

J ECT 2018 Dec 18. Epub 2018 Dec 18.

Social & Scientific Systems, Inc, Durham, NC.

Objective: Electroconvulsive therapy (ECT) is a highly efficacious, well-tolerated treatment in adults. Little is known, however, about its effectiveness in adolescents and young adults. Our objectives were to assess clinical outcomes after acute phase ECT in adolescents and young adults and determine whether screening positive or negative for a substance use disorder (SUD) is associated with differences in treatment outcomes. Read More

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http://dx.doi.org/10.1097/YCT.0000000000000562DOI Listing
December 2018

Neurostimulation for depression in epilepsy.

Epilepsy Behav 2018 Nov 4;88S:25-32. Epub 2018 Jul 4.

Beth Israel Deaconess Medical Center, Massachusetts General Hospital, CIMIT- 125 Nashua Street, Suite 324, Boston, MA 02114, United States. Electronic address:

Epilepsy is often associated with comorbid psychiatric illnesses that can significantly impact its long-term course. The most frequent of these psychiatric comorbidities is major depressive disorder, which affects an estimated 40% of patients with epilepsy. Many patients are underdiagnosed or undertreated, yet managing their mood symptoms is critical to improving their outcomes. Read More

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http://dx.doi.org/10.1016/j.yebeh.2018.06.007DOI Listing
November 2018

Major Adverse Cardiac Events and Mortality Associated with Electroconvulsive Therapy: A Systematic Review and Meta-analysis.

Anesthesiology 2019 Jan;130(1):83-91

From the Departments of Anesthesiology and Intensive Care (A.D., M.M., B.P.) Emergency Medicine (H.H.), Medical University of Vienna, Vienna, Austria the Department of Anesthesiology, Washington University, St. Louis, Missouri (P.N.) Department of Public Health Sciences, University of Chicago, University of Chicago, Illinois (T.K.).

What We Already Know About This Topic: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Cardiac events after electroconvulsive therapy have been reported sporadically, but a systematic assessment of the risk is missing. The goal of this study was to obtain a robust estimate of the incidence of major adverse cardiac events in adult patients undergoing electroconvulsive therapy.

Methods: Systematic review and meta-analysis of studies that investigated electroconvulsive therapy and reported major adverse cardiac events and/or mortality. Read More

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http://dx.doi.org/10.1097/ALN.0000000000002488DOI Listing
January 2019

Cerebellar Contributions to Major Depression.

Front Psychiatry 2018 29;9:634. Epub 2018 Nov 29.

Department of General Psychiatry, Center for Psychosocial Medicine, University of Heidelberg, Heidelberg, Germany.

Extending beyond the motor domain, the cerebellum is involved in various aspects of cognition and affect. Multidisciplinary evidence has demonstrated topographic organization of higher-order cognitive functions within the cerebellum. We here review recent neuroimaging research that indicates cerebellar contributions to major depressive disorder (MDD). Read More

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http://dx.doi.org/10.3389/fpsyt.2018.00634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281716PMC
November 2018

Electroconvulsive therapy induced gray matter increase is not necessarily correlated with clinical data in depressed patients.

Brain Stimul 2018 Dec 4. Epub 2018 Dec 4.

Department of Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany.

Background: Electroconvulsive therapy (ECT) and depression have been associated with brain volume changes, especially in the hippocampus and the amygdala.

Methods: In this retrospective study we collected data from individual pre-post ECT whole brain magnetic resonance imaging scans of depressed patients from six German university hospitals. Gray matter volume (GMV) changes were quantified via voxel-based morphometry in a total sample of 92 patients with major depressive episodes (MDE). Read More

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http://dx.doi.org/10.1016/j.brs.2018.11.017DOI Listing
December 2018

Subdural hematoma and electroconvulsive therapy: A case report and review of the literature.

Neurochirurgie 2018 Dec 13. Epub 2018 Dec 13.

Department of neurosurgery, Hospices civils de Lyon, Hospital for neurology and neurosurgery Pierre Wertheimer, 69003, Lyon, France; Université de Lyon, Université Claude-Bernard, 69003, Lyon, France; Inserm U1127, CNRS 7225, Brain and spine institute, 75006, Paris, France; Sorbonne Universités, université Pierre et Marie Curie, 75005, Paris, France.

Background And Case Presentation: Electroconvulsive therapy (ECT) is a common therapeutic procedure in psychiatry associated with a low rate of complications. We report a rare case of subdural hematoma (SDH) associated with ECT.

Clinical Presentation: a 64 year old woman, with a medical history of persistent depression which required ECT six years previously, underwent ECT following a new acute episode. Read More

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http://dx.doi.org/10.1016/j.neuchi.2018.11.001DOI Listing
December 2018

Electroconvulsive therapy: historical construction of nursing care (1989-2002).

Rev Bras Enferm 2018 ;71(suppl 6):2743-2750

Universidade Federal do Rio de Janeiro, Anna Nery Nursing School. Rio de Janeiro, Rio de Janeiro, Brazil.

Objective: to describe the nursing care performed by the nursing team to the person with mental disorder submitted to ECT and to analyze the implications of the Psychiatric Reform in this care.

Method: socio-historical study, which uses the Thematic Oral History method.

Results: the nursing team is present in a continuous way in the monitoring of people submitted to ECT, performing care before, during and after the same, as well as visualizing the evolution of the technique and also of nursing care itself, however, does not recognize the Psychiatric Reform as agent for this change. Read More

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http://dx.doi.org/10.1590/0034-7167-2018-0168DOI Listing
January 2018

A novel seizure quality index based on ictal parameters for optimizing clinical decision-making in electroconvulsive therapy. Part 2: Validation.

Eur Arch Psychiatry Clin Neurosci 2018 Dec 10. Epub 2018 Dec 10.

Department of Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health, Heidelberg University, J5, 68159, Mannheim, Germany.

Early identification of patients who are at a high risk for an unfavorable outcome to ECT during the treatment course might be beneficial because it provides an opportunity for timely intensification or optimization of stimulus conditions. We aimed to validate a previously developed seizure quality index (SQI) that delivers a clinically relevant outcome prediction early in the treatment course and can be used within common clinical setting. Therefore, a prospective study was conducted. Read More

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http://link.springer.com/10.1007/s00406-018-0962-7
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http://dx.doi.org/10.1007/s00406-018-0962-7DOI Listing
December 2018
2 Reads

Use of electroconvulsive therapy in adolescents with schizophrenia in China.

Child Adolesc Psychiatry Ment Health 2018 5;12:49. Epub 2018 Dec 5.

1Beijing Anding Hospital, Capital Medical University, Ankang Road 5, Xicheng District, Beijing, China.

Background: Electroconvulsive therapy (ECT) is an effective treatment for psychiatric disorders such as schizophrenia, major depression and bipolar disorder. However, few studies have addressed the use of ECT in adolescents with schizophrenia. The aims of our study were to investigate the frequency of ECT, and its relationship with clinical and demographic correlates among adolescents with schizophrenia in China. Read More

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http://dx.doi.org/10.1186/s13034-018-0254-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280503PMC
December 2018

ECT in the Postpartum Period: A Retrospective Case Series from a Tertiary Health Care Center in India.

Indian J Psychol Med 2018 Nov-Dec;40(6):562-567

Department of Psychiatry, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Objective: To evaluate the clinical profile and effectiveness of ECT in females with postpartum onset psychiatric syndromes or worsening of psychiatric disorder during the postpartum period.

Materials And Methods: A retrospective chart review was carried out to identify females who had received ECT during their postpartum period from January2004 to April 2017.

Results: During the study period, 13 females in their postpartum period received ECT, which accounted for 2. Read More

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http://dx.doi.org/10.4103/IJPSYM.IJPSYM_105_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241200PMC
December 2018

An Electrophysiological Biomarker That May Predict Treatment Response to ECT.

J ECT 2018 Dec 7. Epub 2018 Dec 7.

Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX.

Objective: Electroconvulsive therapy (ECT) is the most effective treatment for major depression but also carries risk of cognitive side effects. The ability to predict whether treatment will be effective before initiation of treatment could significantly improve quality of care, reduce suffering, and diminish costs. We sought to carry out a comprehensive and definitive study of the relationship between the background electroencephalography (EEG) and therapeutic response to ECT. Read More

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http://dx.doi.org/10.1097/YCT.0000000000000557DOI Listing
December 2018

Ketamine Versus Midazolam for Depression Relapse Prevention Following Successful Electroconvulsive Therapy: A Randomized Controlled Pilot Trial.

J ECT 2018 Dec 7. Epub 2018 Dec 7.

Centre for Support and Training in Analysis and Research, School of Public Health, Physiotherapy and Sports Science, University College Dublin, Dublin, Ireland.

Objective: Depression relapse after electroconvulsive therapy (ECT) is common (40% at 6 months). Ketamine has a robust antidepressant effect, but there are no reported studies of ketamine for depression relapse prevention. This pilot trial (NCT02414932) was designed to assess feasibility of the proposed trial protocol, including examining reasons for nonrecruitment, nonrandomization, and dropout. Read More

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http://dx.doi.org/10.1097/YCT.0000000000000560DOI Listing
December 2018

Rapid Amelioration of Clozapine-Resistant Thought Broadcast in Schizophrenia With High-Dose Right Unilateral Ultrabrief Electroconvulsive therapy-A Single Case Report.

J ECT 2018 Dec 7. Epub 2018 Dec 7.

Mood Disorders UnitCumberland Hospital Riverview and Department of Psychiatry Westmead Clinical School University of Sydney Westmead, New South Wales Australia Department of PsychiatryWestmead Clinical SchoolUniversity of SydneyWestmead, New South WalesAustralia.

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http://dx.doi.org/10.1097/YCT.0000000000000561DOI Listing
December 2018

Family Presence During Electroconvulsive Therapy.

J ECT 2018 Dec 7. Epub 2018 Dec 7.

Peter James Centre, Eastern Health, Victoria, Australia.

Background: The practice of electroconvulsive therapy (ECT) is often hampered by stigma and myths prevailing among patients and families. Family attendance at ECT has not been systematically studied.

Methods: From January 2017 to May 2018, 69 consecutive patients were approached for family attendance at ECT. Read More

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http://dx.doi.org/10.1097/YCT.0000000000000559DOI Listing
December 2018

Electroconvulsive Therapy and Anticoagulation.

Psychosomatics 2018 Nov 24. Epub 2018 Nov 24.

Oğuzhan Çelik, M.D. Cem Çil, M.D. Bülent Özlek, M.D.Murat Biteker, M.D.?>Muğla University, Faculty of Medicine, Department of Cardiology, Mugla, Muğla Province, Turkey.

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http://dx.doi.org/10.1016/j.psym.2018.11.004DOI Listing
November 2018
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Leveraging Neuroplasticity to Enhance Adaptive Learning: The Potential for Synergistic Somatic-Behavioral Treatment Combinations to Improve Clinical Outcomes in Depression.

Biol Psychiatry 2018 Sep 20. Epub 2018 Sep 20.

Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania. Electronic address:

Until recently, therapeutic development in psychiatry was targeted solely toward symptom reduction. While this is a worthwhile goal, it has yielded little progress in improved therapeutics in the last several decades in the field of mood disorders. Recent advancements in our understanding of pathophysiology suggests that an impairment of neuroplasticity may be a critical part of the development of neuropsychiatric disorders. Read More

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http://dx.doi.org/10.1016/j.biopsych.2018.09.004DOI Listing
September 2018

Electroconvulsive therapy for anti-N-methyl-d-aspartate (NMDA) receptor encephalitis: A systematic review of cases.

Brain Stimul 2018 Dec 4. Epub 2018 Dec 4.

Metro South Addiction and Mental Health, Brisbane, Australia; University of Queensland, Brisbane, Australia.

Background: Anti-NMDA receptor encephalitis most commonly presents with psychiatric symptoms such as behavioural disturbance, catatonia and psychosis. Although the primary treatment is with immunomodulatory therapy, psychiatric symptoms often require adjuvant management. Side effects and treatment resistance limits the use of psychotropics, but the role of ECT has been minimally reviewed. Read More

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http://dx.doi.org/10.1016/j.brs.2018.11.016DOI Listing
December 2018

Treatment-resistant and multi-therapy-resistant criteria for bipolar depression: consensus definition.

Br J Psychiatry 2018 Dec 6:1-9. Epub 2018 Dec 6.

Clinical Senior Lecturer in Mood Disorders and Consultant Psychiatrist,National Affective Disorders Service; Academic Psychiatry Training Programme Lead,Institute of Psychiatry,Psychology and Neuroscience,King's College London,South London and Maudsley NHS Foundation Trust (SLaM); andCRN South London Lead for Mental Health,Centre for Affective Disorders, Institute of Psychiatry,Psychology and Neuroscience,King's College London,South London and Maudsley NHS Foundation Trust (SLaM),UK.

Background: Most people with bipolar disorder spend a significant percentage of their lifetime experiencing either subsyndromal depressive symptoms or major depressive episodes, which contribute greatly to the high levels of disability and mortality associated with the disorder. Despite the importance of bipolar depression, there are only a small number of recognised treatment options available. Consecutive treatment failures can quickly exhaust these options leading to treatment-resistant bipolar depression (TRBD). Read More

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https://www.cambridge.org/core/product/identifier/S000712501
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http://dx.doi.org/10.1192/bjp.2018.257DOI Listing
December 2018
6 Reads

Evidence for increased genetic risk load for major depression in patients assigned to electroconvulsive therapy.

Am J Med Genet B Neuropsychiatr Genet 2018 Dec 2. Epub 2018 Dec 2.

Central Institute of Mental Health, Department of Psychiatry and Psychotherapy, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.

Electroconvulsive therapy (ECT) is the treatment of choice for severe and treatment-resistant depression; disorder severity and unfavorable treatment outcomes are shown to be influenced by an increased genetic burden for major depression (MD). Here, we tested whether ECT assignment and response/nonresponse are associated with an increased genetic burden for major depression (MD) using polygenic risk score (PRS), which summarize the contribution of disease-related common risk variants. Fifty-one psychiatric inpatients suffering from a major depressive episode underwent ECT. Read More

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http://dx.doi.org/10.1002/ajmg.b.32700DOI Listing
December 2018

ECT beyond unipolar major depression: systematic review and meta-analysis of electroconvulsive therapy in bipolar depression.

Acta Psychiatr Scand 2018 Dec 3. Epub 2018 Dec 3.

Department of Psychiatry, Providence Care Hospital, Queen's University, Kingston, ON, Canada.

Objective: In this systematic review and meta-analysis, the response, remission, and speed of response in adults with major depressive disorder (MDD) and bipolar disorder in depressive episode (BDD) receiving an acute course of electroconvulsive therapy (ECT) were quantitatively analyzed.

Methods: Using the Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines, 1660 citations were identified through five electronic databases. Nineteen articles met final inclusion criteria for meta-analysis. Read More

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http://dx.doi.org/10.1111/acps.12994DOI Listing
December 2018
1 Read

Treatment of catatonia in autism spectrum disorders.

Authors:
L E Wachtel

Acta Psychiatr Scand 2019 Jan 2;139(1):46-55. Epub 2018 Dec 2.

Kennedy Krieger Institute, Baltimore, MD, USA.

Objective: To review the treatment courses of 22 autistic patients diagnosed with catatonia over a 12-year period, including treatment with benzodiazepines and electroconvulsive therapy.

Method: Retrospective review of inpatient and outpatient records of 22 autistic youth presenting to a neurobehavioral service who were treated for catatonia.

Results: Six girls and 16 boys ranging from ages 8 to 26 years old presenting for neurobehavioral assessment were found to meet criteria for catatonia according to the DSM5 and were treated for such. Read More

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http://dx.doi.org/10.1111/acps.12980DOI Listing
January 2019

Electroconvulsive Therapy While Receiving Oral Anticoagulation for Deep Venous Thrombosis: Report on Eight Cases and a Review of the Literature.

Psychosomatics 2018 Nov 7. Epub 2018 Nov 7.

University of Yamanashi, Faculty of Medicine, Department of Neuropsychiatry and Clinical Ethics, Yamanashi, Japan; Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan. Electronic address:

Background: Electroconvulsive therapy (ECT) is indicated for critical psychiatric conditions, which themselves constitute a risk for deep venous thrombosis (DVT) owing to prolonged immobility, dehydration, and venous stasis.

Objective: We describe challenging instances of ECT implementation while taking direct oral anticoagulants (DOACs).

Method: We report on 8 patients receiving DOACs for DVT who were successfully treated with ECT at the University of Yamanashi Hospital. Read More

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http://dx.doi.org/10.1016/j.psym.2018.10.007DOI Listing
November 2018
1 Read

Cognitive functioning in patients treated with electroconvulsive therapy.

Neuropsychiatr Dis Treat 2018 8;14:3025-3031. Epub 2018 Nov 8.

Department of Psychiatry, First Faculty of Medicine, Charles University, General University Hospital in Prague, Prague, Czech Republic,

Background: Electroconvulsive therapy (ECT) is an effective treatment method for severe mental illnesses. ECT has gone through significant modernization. Side effects of ECT have largely decreased. Read More

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http://dx.doi.org/10.2147/NDT.S182423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231503PMC
November 2018

Electro convulsive therapy: Modification of its effect on the autonomic nervous system using anti-cholinergic drugs.

Psychiatry Res 2018 Nov 23;271:239-246. Epub 2018 Nov 23.

Institute of Clinical Medicine, Copenhagen University, Copenhagen, Denmark; Psychiatric Centre Copenhagen, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark.

The antidepressant efficacy of electroconvulsive therapy (ECT) is correlated to the quality of the seizure as measured by EEG but has also been linked to the magnitude of changes in hemodynamic variables. Muscarinic receptor antagonists are frequently used in the treatment, and are known to affect the hemodynamic response. We hypothesized that atropine and glycopyrrolate alter the hemodynamic and autonomic hormonal response to ECT. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.11.035DOI Listing
November 2018
1 Read

Late life depression: nursing actions that can help.

Authors:
Sherri Melrose

Perspect Psychiatr Care 2018 Nov 30. Epub 2018 Nov 30.

Faculty of Health Disciplines, Centre for Nursing and Health Studies, Athabasca University, Athabasca, Alberta.

Purpose: This article explains the symptoms of late life depression (LLD) and discusses evidence-informed actions that nurses can implement to provide older adults with the help they need.

Conclusions: Recognizing and addressing depression in older adults can enhance quality of life.

Practice Implications: People with LLD may not appear sad or express feelings of depression. Read More

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http://doi.wiley.com/10.1111/ppc.12341
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http://dx.doi.org/10.1111/ppc.12341DOI Listing
November 2018
3 Reads

Staged bilateral pallidotomy for dystonic camptocormia: case report.

Authors:

J Neurosurg 2018 Oct 1:1-4. Epub 2018 Oct 1.

Camptocormia is a rare, involuntary movement disorder, presenting as truncal flexion while standing or walking, and is mainly observed as a feature of Parkinson's disease (PD) and primary dystonia. Deep brain stimulation (DBS) of the globus pallidus internus is effective for refractory camptocormia observed with PD or dystonia. However, the effectiveness of pallidotomy for camptocormia has not been investigated. Read More

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http://dx.doi.org/10.3171/2018.5.JNS1840DOI Listing
October 2018
6 Reads

Hip Hip Hooray, ECT turns 80!

Authors:
Patrick Clarke

Australas Psychiatry 2018 Nov 26:1039856218815753. Epub 2018 Nov 26.

Senior Clinical Lecturer, The University of Adelaide, Adelaide, SA, and; Director of Transcranial Magnetic Stimulation, Ramsay Health, North Adelaide, SA, Australia.

Objective:: This paper reviews the history of electroconvulsive therapy (ECT) with an emphasis on the Australian context over the past 30 years. The review includes data collection, the contribution of the RANZCP, and changes in legislation.

Conclusion:: ECT remains the most effective treatment for severe depression. Read More

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http://dx.doi.org/10.1177/1039856218815753DOI Listing
November 2018
1 Read

ECT-induced brain plasticity correlates with positive symptom improvement in schizophrenia by voxel-based morphometry analysis of grey matter.

Brain Stimul 2018 Nov 17. Epub 2018 Nov 17.

Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, 200030, China; CAS Center for Excellence in Brain Science and Intelligence Technology (CEBSIT), Chinese Academy of Science, China; Brain Science and Technology Research Center, Shanghai Jiaotong University, Shanghai, 200030, China; Bio-X Institute, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiaotong University, Shanghai, 200030, China. Electronic address:

Background: Electroconvulsive therapy (ECT) is often considered as an augmentation of antipsychotic treatment for schizophrenia in drug-refractory cases. However, the mechanisms underlying the observed therapeutic effects are still not understood.

Objective: We aimed to investigate changes in whole brain grey matter volume (GMV) before and after modified ECT. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1935861X183037
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http://dx.doi.org/10.1016/j.brs.2018.11.006DOI Listing
November 2018
6 Reads

Influence of age on ECT efficacy in depression and the mediating role of psychomotor retardation and psychotic features.

J Psychiatr Res 2018 Nov 15;109:41-47. Epub 2018 Nov 15.

Department of Psychiatry, Erasmus University Medical Centre, Rotterdam, the Netherlands.

Objective: To investigate whether older age predicts a higher efficacy of electroconvulsive therapy (ECT) in severely depressed patients. Also, to analyze whether psychomotor disturbance and/or psychotic features might explain the potential higher efficacy of ECT in older age.

Method: A total of 96 patients with major depressive disorder treated with bilateral ECT were evaluated. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00223956183116
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http://dx.doi.org/10.1016/j.jpsychires.2018.11.014DOI Listing
November 2018
3 Reads

A Pilot Study on Daily Intensive ECT over 8 Days Improved Positive and Negative Symptoms and General Psychopathology of Patients with Treatment-Resistant Schizophrenia up to 4 Weeks after Treatment.

Neuropsychobiology 2018 Nov 21:1-9. Epub 2018 Nov 21.

Sleep Disorders Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Objective: For patients with treatment-resistant schizophrenia (TRS) who do not respond to drug therapy, electroconvulsive therapy (ECT) is often employed as an additional treatment. The aims of the present study were to investigate to what extent an 8-day daily ECT treatment might reduce symptoms of schizophrenia among patients with TRS both in the short term (end of the treatment) and medium term, that is 4 and 12 weeks after the treatment.

Methods: Fourteen patients with TRS based on DSM-5 criteria took part in the present study. Read More

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http://dx.doi.org/10.1159/000494698DOI Listing
November 2018
6 Reads

Racial Disparities in the Administration of ECT in Texas, 1998-2013.

J ECT 2018 Nov 17. Epub 2018 Nov 17.

University of Texas Southwestern Medical Center, Dallas, TX.

Objective: Electroconvulsive therapy (ECT) is a treatment of choice for severe depression but has been underutilized among black patients. This study investigates racial disparities in the administration of ECT in the state of Texas between 1998 and 2013 using population data.

Design: Data from the Texas Department of State Health Services were obtained corresponding to the use for all ECT conducted in nonfederal settings during the period from January 2, 1998, to August 30, 2013. Read More

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http://dx.doi.org/10.1097/YCT.0000000000000555DOI Listing
November 2018

Transnasal Humidified Rapid-Insufflation Ventilatory Exchange During Electroconvulsive Therapy: A Feasibility Study.

J ECT 2018 Nov 17. Epub 2018 Nov 17.

Department of Psychiatry GGZ inGeest/VU University Medical Center, Amsterdam, the Netherlands.

Background: In electroconvulsive therapy (ECT), a generalized seizure is provoked under general anesthesia. Standard airway management is done by face mask ventilation, but this is difficult during generalized seizure. Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) is a method to increase apnea tolerance and permit apnea oxygenation. Read More

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http://dx.doi.org/10.1097/YCT.0000000000000556DOI Listing
November 2018
2 Reads

Brain Volumetric Correlates of Right Unilateral Versus Bitemporal Electroconvulsive Therapy for Treatment-Resistant Depression.

J Neuropsychiatry Clin Neurosci 2018 Nov 21:appineuropsych18080177. Epub 2018 Nov 21.

From the Department of Psychiatry, Bellvitge University Hospital-IDIBELL, L'Hospitalet de Llobregat, Barcelona (MC, IM-Z, RH-R, OC-R, JMM, MU, CS-M); the Department of Clinical Sciences, School of Medicine, University of Barcelona (MC, IM-Z, RH-R, JMM, MU); CIBERSAM, Carlos III Health Institute, Madrid (MC, NC, JP, EV, RH-R, OC-R, JMM, MU, CS-M); the Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston (MC, EL, NM, MH, JAC); the Mental Health Department, Parc Taulí Sabadell, Universitat Autònoma de Barcelona (NC); the Radiology Department, MRI Research Unit, Hospital del Mar, Barcelona (JP); Sant Joan de Déu Barcelona-Children's Hospital, Barcelona (EV); and the Department of Psychobiology and Methodology in Health Sciences, Universitat Autònoma de Barcelona (CS-M).

The selection of a bitemporal (BT) or right unilateral (RUL) electrode placement affects the efficacy and side effects of ECT. Previous studies have not entirely described the neurobiological underpinnings of such differential effects. Recent neuroimaging research on gray matter volumes is contributing to our understanding of the mechanism of action of ECT and could clarify the differential mechanisms of BT and RUL ECT. Read More

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http://dx.doi.org/10.1176/appi.neuropsych.18080177DOI Listing
November 2018
4 Reads

A companion to the preclinical common data elements for pharmacologic studies in animal models of seizures and epilepsy. A Report of the TASK3 Pharmacology Working Group of the ILAE/AES Joint Translational Task Force.

Epilepsia Open 2018 Nov 15;3(Suppl Suppl 1):53-68. Epub 2018 Sep 15.

Department of Pharmacology, Toxicology, and Pharmacy University of Veterinary Medicine Hannover Hannover Germany.

Preclinical pharmacology studies in animal models of seizures and epilepsy have provided a platform to identify more than 20 antiseizure drugs in recent decades. To minimize variability in lab-to-lab studies and to harmonize approaches to data collection and reporting methodology in pharmacologic evaluations of the next generation of therapies, we present common data elements (CDEs), case report forms (CRFs), and this companion manuscript to help with the implementation of methods for studies in established preclinical seizure and epilepsy models in adult rodents. The development of and advocacy for CDEs in preclinical research has been encouraged previously by both clinical and preclinical groups. Read More

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http://doi.wiley.com/10.1002/epi4.12254
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http://dx.doi.org/10.1002/epi4.12254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210039PMC
November 2018
4 Reads

When to switch from bilateral to unilateral electroconvulsive therapy: A simple way to elicit seizures in high seizure threshold cases.

Neuropsychopharmacol Rep 2018 Nov 16. Epub 2018 Nov 16.

Hokkaido Prefectural Midorigaoka Hospital, Midorigaoka, Japan.

Aims: Although electroconvulsive therapy (ECT) is effective for various psychiatric disorders, its therapeutic effect depends on the occurrence of adequate seizures. Thus, the management of inadequate seizures remains a clinical problem. Here, we aimed to develop a simple method to elicit adequate seizures in high seizure threshold patients during ECT sessions. Read More

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http://doi.wiley.com/10.1002/npr2.12039
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http://dx.doi.org/10.1002/npr2.12039DOI Listing
November 2018
2 Reads

Remifentanil as an adjunct to anaesthesia for electroconvulsive therapy fails to confer long-term benefits.

Br J Anaesth 2018 Dec 16;121(6):1282-1289. Epub 2018 Aug 16.

Department of Clinical Medicine, University of Bergen, Bergen, Norway; Department of Psychiatry, Stavanger University Hospital, Stavanger, Norway.

Background: Adding the μ-opioid receptor agonist remifentanil to agents used to induce general anaesthesia in electroconvulsive therapy (ECT) can reduce the required doses of induction agents and their unfavourable effects on seizure threshold and quality. However, whether remifentanil has favourable long-term treatment effects in terms of response and remission rates, speed of response and remission, and side-effects has not been studied.

Methods: This retrospective, register-based cohort study involved patients with major depression consecutively treated at two units at different hospitals in Norway with the same ECT procedure. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00070912183058
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http://dx.doi.org/10.1016/j.bja.2018.07.011DOI Listing
December 2018
2 Reads

Structural changes in amygdala nuclei, hippocampal subfields and cortical thickness following electroconvulsive therapy in treatment-resistant depression: longitudinal analysis.

Br J Psychiatry 2018 Nov 16:1-9. Epub 2018 Nov 16.

Associate Professor and Head of the Neuroimaging Labs, Department of Psychiatry and Psychotherapy,Medical University of Vienna,Austria.

Background: Electroconvulsive therapy (ECT) is the treatment of choice for severe mental illness including treatment-resistant depression (TRD). Increases in volume of the hippocampus and amygdala following ECT have consistently been reported.AimsTo investigate neuroplastic changes after ECT in specific hippocampal subfields and amygdala nuclei using high-resolution structural magnetic resonance imaging (MRI) (trial registration: clinicaltrials. Read More

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https://www.cambridge.org/core/product/identifier/S000712501
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http://dx.doi.org/10.1192/bjp.2018.224DOI Listing
November 2018
8 Reads

Tractography Analysis for Electroconvulsive Therapy.

Conf Proc IEEE Eng Med Biol Soc 2018 Jul;2018:6133-6136

Computational human head models have been used in electrophysiological studies, and they have been able to provide useful information that is unable or difficult to acquire from experimental or imaging studies. However, most of these models are purely volume conductor models that overlooked the electric excitability of axons in the white matter of the brain. This study combined a finite element (FE) model of electroconvulsive therapy (ECT) with a whole-brain tractography analysis as well as the cable theory of neuronal excitation. Read More

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http://dx.doi.org/10.1109/EMBC.2018.8513489DOI Listing

Estimating The Quality of Electroconvulsive Therapy Induced Seizures Using Decision Tree and Fuzzy Inference System Classifiers.

Conf Proc IEEE Eng Med Biol Soc 2018 Jul;2018:3677-3680

Electroconvulsive therapy (ECT) is an effective and widely used treatment for major depressive disorder, in which a brief electric current is passed through the brain to trigger a brief seizure. This study aims to identify seizure quality rating by utilizing a set of seizure parameters. We used 750 ECT EEG recordings in this experiment. Read More

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https://ieeexplore.ieee.org/document/8513334/
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http://dx.doi.org/10.1109/EMBC.2018.8513334DOI Listing
July 2018
3 Reads

Is Electroconvulsive Therapy any More Effective than Simulated Electroconvulsive Therapy in Treatment-Resistant Depression?

Authors:
Alexander Bow

Psychiatr Danub 2018 Nov;30(Suppl 7):502-507

University of Cambridge, Emmanuel College, Cambridge, CB2 3AP, UK,

Background: Electroconvulsive therapy (ECT) fell out of favour towards the end of the 20 century with the advent of effective and well-tolerated antidepressants. It is now experiencing somewhat of a 'renaissance' in England, with an 11 percent increase in the number of ECT treatments carried out in 2015-16 compared with 2012-13, which represents approximately 2,000 additional treatments.

Aims: This paper seeks to examine clinical trials comparing the efficacy of real ECT with simulated ECT in treatment-resistant depression (TRD) to determine whether the resurgence of ECT in recent years is justified. Read More

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November 2018
1 Read

Forbidden insanity: the systematic denial of mental health issues from a state-run psychiatry.

Psychiatr Danub 2018 Dec;30(4):385-389

Faculty of Medicine, University of Medicine in Tirana, Tirana, Albania,

The authors discuss the issue of psychiatric care and patients during the second half of XX century in Albania, when the country was under an absolute regime of communism. Completely isolated from the rest of the world, the territory remained a prohibited area for scholars, and local authors due to censorship or self-censorship, offered very scarce information. The general feeling of the public was that of a denial of psychic disorders in total, combined with the fear that this kind of disorders has ever since provoked. Read More

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http://www.psychiatria-danubina.com/UserDocsImages/pdf/dnb_v
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http://dx.doi.org/10.24869/psyd.2018.385DOI Listing
December 2018
8 Reads
0.653 Impact Factor

[Brain stimulation for the selective treatment of schizophrenia symptom domains : Non-invasive and invasive concepts].

Nervenarzt 2018 Nov 14. Epub 2018 Nov 14.

Abteilung für Medizinische Psychologie, Klinik und Poliklinik für Psychiatrie und Psychotherapie, Universitätsklinikum Bonn, Sigmund-Freud-Str. 25, 53105, Bonn, Deutschland.

Given that one third of patients with schizophrenia (SZ) only show limited response to established treatments, alternative therapeutic strategies such as non-invasive/invasive brain stimulation approaches have emerged as an adjunctive treatment option for distinct SZ symptom domains (e.g. acoustic hallucinations, negative/positive symptoms and cognitive impairment). Read More

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http://link.springer.com/10.1007/s00115-018-0640-z
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http://dx.doi.org/10.1007/s00115-018-0640-zDOI Listing
November 2018
2 Reads

[Accessibility to Electroconvulsive Therapy in Hungary].

Psychiatr Hung 2018 ;33(3):266-269

Jahn Ferenc Del-pesti Korhaz, Pszichiatriai es Addiktologai Centrum, Budapest, Hungary, E-mail:

Introduction: In spite of its efficacy, use of electroconvulsive therapy (ECT) has been declined in Hungary over the past decade. This survey explores the circumstances that have obstructed the accessibility to ECT in Hungary.

Methods: This study was part of a comprehensive survey on the use of ECT in which two semi-structured questionnaires with 25 and 6 questions were sent out to all psychiatric departments in Hungary. Read More

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January 2018

Mechanisms of Antidepressant Response to Electroconvulsive Therapy Studied With Perfusion Magnetic Resonance Imaging.

Biol Psychiatry 2018 Oct 5. Epub 2018 Oct 5.

Ahmanson-Lovelace Brain Mapping Center, University of California Los Angeles, Los Angeles, California; Department of Neurology, and Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, California.

Background: Converging evidence suggests that electroconvulsive therapy (ECT) induces neuroplasticity in patients with severe depression, though how this relates to antidepressant response is less clear. Arterial spin-labeled functional magnetic resonance imaging tracks absolute changes in cerebral blood flow (CBF) linked with brain function and offers a potentially powerful tool when observing neurofunctional plasticity with functional magnetic resonance imaging.

Methods: Using arterial spin-labeled functional magnetic resonance imaging, we measured global and regional CBF associated with clinically prescribed ECT and therapeutic response in patients (n = 57, 30 female) before ECT, after two treatments, after completing an ECT treatment "index" (∼4 weeks), and after long-term follow-up (6 months). Read More

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http://dx.doi.org/10.1016/j.biopsych.2018.09.021DOI Listing
October 2018

Changes in cardiac autonomic nervous system activity during a course of electroconvulsive therapy.

Neuropsychopharmacol Rep 2018 Nov 9. Epub 2018 Nov 9.

Liaison Psychiatry and Palliative Medicine, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

Aim: Although electroencephalogram (EEG) seizure duration and seizure threshold change during a course of electroconvulsive therapy, the mechanisms by which these factors influence heart rate during subsequent electroconvulsive therapy sessions are currently unclear. In the current study, we investigated changes in heart rate during electroconvulsive therapy.

Methods: We recorded electroencephalography and electrocardiography during electroconvulsive therapy in 12 patients with major depressive disorder. Read More

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http://doi.wiley.com/10.1002/npr2.12037
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http://dx.doi.org/10.1002/npr2.12037DOI Listing
November 2018
4 Reads

Corrigendum to 'Ketamine in electroconvulsive therapy for depressive disorder: A systematic review and meta-analysis' [Journal of Psychiatric Research 104 (2018) 144-156].

J Psychiatr Res 2019 Jan 6;108. Epub 2018 Nov 6.

Department of Anesthesiology, The First Affiliated Hospital of Chongqing Medical University, China.

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http://dx.doi.org/10.1016/j.jpsychires.2018.09.009DOI Listing
January 2019
3 Reads

Advances in Technique and Understanding Mechanisms of Action: Adding to the Evidence Base in Electroconvulsive Therapy (ECT).

J ECT 2018 12;34(4):209-210

From the Department of Electroconvulsive Therapy (ECT), New York Community Hospital, Brooklyn; and Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY.

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http://dx.doi.org/10.1097/YCT.0000000000000552DOI Listing
December 2018

The Safety of Electroconvulsive Therapy in Patients With Implanted Deep Brain Stimulators: A Review of the Literature and Case Report.

J ECT 2018 Nov 7. Epub 2018 Nov 7.

Division of Geriatric Psychiatry, Department of Psychiatry, University of Maryland School Medicine, Baltimore, MD.

Currently there is no consensus statement about the safety of electroconvulsive therapy in patients who have implanted electrodes for deep brain stimulation. We present a summary of the existing literature on this topic, consisting of 21 cases, and then report a case performed at the University of Maryland Medical Center. Notably, with appropriate safety precautions and careful patient selection, there were no adverse events reported in the literature that were related to the presence of the deep brain stimulation device in any of the cases. Read More

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http://dx.doi.org/10.1097/YCT.0000000000000554DOI Listing
November 2018

A Systematic Review of the Utility of Electroconvulsive Therapy in Broadly Defined Obsessive-Compulsive-Related Disorders.

Prim Care Companion CNS Disord 2018 Oct 18;20(5). Epub 2018 Oct 18.

Rua Visconde de Pirajá, 547, Sala 617, Ipanema, Rio de Janeiro, CEP: 22410-003.

Objective: To assess the efficacy of electroconvulsive therapy (ECT) in DSM-5 obsessive-compulsive-related disorders (OCRDs) and conditions subsumed under an "extended" OCD spectrum, including tic disorders and self-injurious behaviors.

Data Sources: A systematic search of the MEDLINE, Web of Science, Scopus, and LILACS databases and other sources was performed between June 6 and July 2, 2017. Search terms included (Autis*) AND (ECT OR electroconvulsive), (Self-injur*) AND (ECT OR electroconvulsive), (Tic* OR Tourette) AND (ECT OR electroconvulsive), (Body Dysmorphic Disorder OR Dysmorphophobi*) AND (ECT OR electroconvulsive), (Hoard*) AND (ECT OR electroconvulsive), (Trichotillomani*) AND (ECT OR electroconvulsive), (Skin Picking OR Excoriation) AND (ECT OR electroconvulsive), (Grooming) AND (ECT OR electroconvulsive), (Kleptomani*) AND (ECT OR electroconvulsive), and (Pyromani*) AND (ECT OR electroconvulsive). Read More

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http://www.psychiatrist.com/PCC/article/Pages/2018/v20n05/18
Publisher Site
http://dx.doi.org/10.4088/PCC.18r02342DOI Listing
October 2018
15 Reads