16,437 results match your criteria Electroconvulsive Therapy


Machine Learning Algorithm-Based Prediction Model for the Augmented Use of Clozapine with Electroconvulsive Therapy in Patients with Schizophrenia.

J Pers Med 2022 Jun 14;12(6). Epub 2022 Jun 14.

Department of Psychiatry, Hanyang University College of Medicine, Seoul 04763, Korea.

The augmentation of clozapine with electroconvulsive therapy (ECT) has been an optimal treatment option for patients with treatment- or clozapine-resistant schizophrenia. Using data from the Research on Asian Psychotropic Prescription Patterns for Antipsychotics survey, which was the largest international psychiatry research collaboration in Asia, our study aimed to develop a machine learning algorithm-based substantial prediction model for the augmented use of clozapine with ECT in patients with schizophrenia in terms of precision medicine. A random forest model and least absolute shrinkage and selection operator (LASSO) model were used to develop a substantial prediction model for the augmented use of clozapine with ECT. Read More

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Association of Clinical and Demographic Characteristics With Response to Electroconvulsive Therapy in Mania.

JAMA Netw Open 2022 Jun 1;5(6):e2218330. Epub 2022 Jun 1.

University Health Care Research Centre, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.

Importance: Knowledge of the effectiveness of electroconvulsive therapy (ECT) in the treatment of manic episodes is based on clinical experience, but empirical evidence is scarce. Moreover, prognostic factors associated with response to ECT in patients with mania are poorly understood.

Objective: To investigate the response to ECT in patients with manic episodes. Read More

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Repetitive Transcranial Magnetic Stimulation for the Treatment of Resistant Depression: A Scoping Review.

Behav Sci (Basel) 2022 Jun 17;12(6). Epub 2022 Jun 17.

Department of Psychiatry, Faculty of Medicine and Dentistry, University of Alberta, 1E1 Walter Mackenzie Health Sciences Centre (WMC), 8440 112 St NW, Edmonton, AB T6G 2B7, Canada.

Treatment-resistant depression (TRD) is associated with significant disability, and due to its high prevalence, it results in a substantive socio-economic burden at a global level. TRD is the inability to accomplish and/or achieve remission after an adequate trial of antidepressant treatments. Studies comparing repetitive transcranial magnetic stimulation (rTMS) with electroconvulsive therapy (ECT) and pharmacotherapy have revealed evidence of the therapeutic efficacy of rTMS in TRD. Read More

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Magnetic resonance imaging-guided laser interstitial thermal therapy for refractory focal epilepsy in a patient with a fully implanted RNS system: illustrative case.

J Neurosurg Case Lessons 2022 May 23;3(21):CASE22117. Epub 2022 May 23.

Department of Neurosurgery, Perelman School of Medicine of the University of Pennsylvania, Pennsylvania Hospital, Philadelphia, Pennsylvania.

Background: The resective surgery plus responsive neurostimulation (RNS) system is an effective treatment for patients with refractory focal epilepsy. Furthermore, the long-term intracranial electroencephalography data provided by the system can inform a future resection or ablation procedure. RNS patients may undergo 1. Read More

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Thorough consideration of electroconvulsive therapy (ECT) in treatment-resistant psychiatric disorders.

Mol Psychiatry 2022 Jun 22. Epub 2022 Jun 22.

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health (CIMH), Medical Faculty Mannheim, University of Heidelberg, Square J 5, D-68159, Mannheim, Germany.

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A Severe Neuroleptic Malignant Syndrome Treated with Daily Electroconvulsive Therapy: A Case Report.

Turk Psikiyatri Derg 2022 ;33(2):139-142

Neuroleptic malignant syndrome (NMS) is a rare but life-threatening condition caused by dopamine modulating medications, particularly antipsychotics. First-line treatments of neuroleptic malignant syndrome are supportive care, discontinuation of the offending agent and pharmacotherapy. In drug-resistant and severe situations, electroconvulsive therapy (ECT) is recommended as well. Read More

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The enigma of vascular depression in old age: a critical update.

Authors:
Kurt A Jellinger

J Neural Transm (Vienna) 2022 Jun 15. Epub 2022 Jun 15.

Institute of Clinical Neurobiology, Alberichgasse 5/13, 1150, Vienna, Austria.

Depression is common in older individuals and is associated with high disability and increased mortality, yet the factors predicting late-life depression (LLD) are poorly understood. The relationship between of depressive disorder, age- and disease-related processes have generated pathogenic hypotheses and provided new treatment options. LLD syndrome is often related to a variety of vascular mechanisms, in particular hypertension, cerebral small vessel disease, white matter lesions, subcortical vascular impairment, and other processes (e. Read More

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Comparison of effect of etomidate with propofol on hemodynamics during modified electroconvulsive therapy.

J Anaesthesiol Clin Pharmacol 2022 Jan-Mar;38(1):104-110. Epub 2022 Apr 25.

Department of Anesthesia and Critical Care, Government Medical College and Hospital, Chandigarh, India.

Background And Aims: Studies comparing the effect of propofol and etomidate on hemodynamic parameters during electroconvulsive therapy (ECT) have shown ambiguous results. Although some studies observed a larger increase in blood pressure and heart rate during the use of etomidate than propofol in ECT, whereas some studies have shown no difference in hemodynamic parameters with the use of etomidate or propofol. Most of the studies done to compare the hemodynamic effects of etomidate and propofol were limited by small sample size or retrospective in nature. Read More

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National Network of Depression Centers' Recommendations on Harmonizing Clinical Documentation of Electroconvulsive Therapy.

J ECT 2022 Mar 2. Epub 2022 Mar 2.

Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC.

Electroconvulsive therapy (ECT) is a highly therapeutic and cost-effective treatment for severe and/or treatment-resistant major depression. However, because of the varied clinical practices, there is a great deal of heterogeneity in how ECT is delivered and documented. This represents both an opportunity to study how differences in implementation influence clinical outcomes and a challenge for carrying out coordinated quality improvement and research efforts across multiple ECT centers. Read More

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Mirror-Image Comparison of Maintenance Electroconvulsive Treatment Effectiveness in Affective and Psychotic Disorders.

J ECT 2022 Jun 11. Epub 2022 Jun 11.

Department of Psychiatry, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Objectives: The study aimed to investigate the effectiveness of maintenance electroconvulsive therapy (mECT) with respect to the hospitalization duration, number of hospitalizations, and major and minor treatment changes with a mirror-image study design.

Methods: Medical charts of patients who received at least a 3-month-long course of mECT were reviewed. The records of 36 patients (17 with psychotic disorders, 19 with affective disorders) were retrospectively examined for 2 periods with the same duration; during the mECT (post-mECT) and before the mECT (pre-mECT). Read More

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Asystole During Electroconvulsive Therapy: Does Electrode Placement Matter? A Systematic Review.

J ECT 2022 Jun 11. Epub 2022 Jun 11.

From the KU Leuven, Department of Neurosciences, Research Group Psychiatry, Neuropsychiatry, Academic Center for ECT and Neuromodulation (AcCENT), University Psychiatric Center KU Leuven, Kortenberg.

Abstract: Asystole presenting at the start of electrical stimulus application during electroconvulsive therapy (ECT) is a relatively common occurrence. It is most likely caused by vagal nerve stimulation, affecting autonomic cardiac tone. This article reviews the effect of the electrode placement (EP) on the incidence and severity of bradycardia and asystole. Read More

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Electroconvulsive Therapy in Children and Adolescents in Germany-A Case Series From 3 University Hospitals.

J ECT 2022 Jun 11. Epub 2022 Jun 11.

From the Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim.

Objective: Electroconvulsive therapy (ECT) is a well-established, safe, and efficacious treatment for severe psychiatric disorders. In children and adolescents, it is used much less frequently than in adults, likely because of a lack of knowledge.

Methods: We retrospectively analyzed all patients aged 12 to 17 years who completed a course of ECT at 3 psychiatric university hospitals in Germany between 2010 and 2020. Read More

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A Case Report of Leukocytosis During Modified Electroconvulsive Therapy of Paranoid Personality Disorder.

Front Psychiatry 2022 26;13:899847. Epub 2022 May 26.

Department of General Practice, West China Hospital, Sichuan University, Chengdu, China.

Introduction: Modified electroconvulsive therapy (MECT) is a viable therapeutic option for patients with mood disorders and schizophrenia. We found that there is a relationship between MECT and leukocytosis. To the best of our knowledge, this is the first case of this problem. Read More

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Effectiveness of Non-Pharmacological Interventions for Agitation during Post-Traumatic Amnesia following Traumatic Brain Injury: A Systematic Review.

Neuropsychol Rev 2022 Jun 10. Epub 2022 Jun 10.

Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Melbourne, Australia.

Agitation is common in the early recovery period following traumatic brain injury (TBI), known as post-traumatic amnesia (PTA). Non-pharmacological interventions are frequently used to manage agitation, yet their efficacy is largely unknown. This systematic review aims to synthesize current evidence on the effectiveness of non-pharmacological interventions for agitation during PTA in adults with TBI. Read More

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The effect of risperidone and electroconvulsive therapy on corrected QT interval in electrocardiogram of psychiatric patients.

ARYA Atheroscler 2021 Jul;17(4):1-6

PhD, Children Growth Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran.

Background: Some types of antidepressants and antipsychotic medications have cardiovascular side effects that can be life-threatening. Electroconvulsive therapy (ECT) is capable of generating physiological stress and may lead to increased QT interval followed by arrhythmias. Risperidone can also increase the risk of arrhythmia by increasing the corrected QT (QTc) interval. Read More

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Improved Safety of Hybrid Electroconvulsive Therapy Compared With Standard Electroconvulsive Therapy in Patients With Major Depressive Disorder: A Randomized, Double-Blind, Parallel-Group Pilot Trial.

Front Psychiatry 2022 23;13:896018. Epub 2022 May 23.

Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China.

Objectives: ECT is a rapid and effective treatment for depression. While efficacy is often remarkable over the initial 3-4 sessions, the efficacy of later sessions is less rapid, and the side-effects, especially cognitive impairment limit its use. To preliminarily compare the efficacy and acceptability of a novel hybrid-ECT (HECT) protocol for patients with major depressive disorder (MDD) with standard ECT, we conducted this pilot trial. Read More

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The Role of Acetylcholinesterase Inhibitors in the Treatment of Prolonged Postelectroconvulsive Therapy Delirium.

Case Rep Psychiatry 2022 30;2022:6966882. Epub 2022 May 30.

Christiana Care Health System, 4755 Ogletown Stanton Rd, Newark, DE 19718, USA.

Electroconvulsive therapy (ECT) is an extremely effective treatment modality for severe depression but is often associated with transient or persistent cognitive impairment. ECT-induced cognitive impairment, however, can serve as a deterrent to completion of treatment. We present a case of a prolonged post-ECT delirium lasting approximately 3 weeks in which donepezil, an acetylcholinesterase inhibitor, was used and was successful in shortening the duration of post-ECT delirium. Read More

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Long-term Outcome Following Electroconvulsive Therapy for Late-Life Depression: Five-Year Follow-up Data From the MODECT Study.

Am J Geriatr Psychiatry 2022 May 18. Epub 2022 May 18.

GGZ inGeest Specialized Mental Health Care, Old Age Psychiatry, Amsterdam, The Netherlands; Amsterdam UMC location Vrije Universiteit Amsterdam, Psychiatry, Amsterdam, The Netherlands; Amsterdam Public Health Research Institute, Mental Health, Amsterdam, The Netherlands; Amsterdam Neuroscience, Mood, Anxiety, Psychosis, Sleep & Stress program, Amsterdam, The Netherlands.

Objective: Electroconvulsive therapy (ECT) is the most effective treatment for late-life depression (LLD). Research addressing long-term outcome following an acute course of ECT for LLD is limited. We aimed to describe relapse, cognitive impairment and survival 5 years after a treatment with ECT for severe LLD, and assess the association of clinical characteristics with all three outcome measures. Read More

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Electroconvulsive Therapy-Induced Changes in Functional Brain Network of Major Depressive Disorder Patients: A Longitudinal Resting-State Electroencephalography Study.

Front Hum Neurosci 2022 18;16:852657. Epub 2022 May 18.

Brain Health Engineering Laboratory, School of Medical Technology, Beijing Institute of Technology, Beijing, China.

Objectives: Several studies have shown abnormal network topology in patients with major depressive disorder (MDD). However, changes in functional brain networks associated with electroconvulsive therapy (ECT) remission based on electroencephalography (EEG) signals have yet to be investigated.

Methods: Nineteen-channel resting-state eyes-closed EEG signals were collected from 24 MDD patients pre- and post-ECT treatment. Read More

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Characteristics of the treatments for each severity of major depressive disorder: A real-world multi-site study.

Asian J Psychiatr 2022 May 18;74:103174. Epub 2022 May 18.

Katsumoto Mental Clinic, Osaka, Japan.

Purpose: In the treatment guidelines for major depressive disorder (MDD), the recommended treatment differs based on the severity. However, the type of treatment provided based on the severity of MDD in real-world clinical practice has not been investigated. In this study, we clarified the actual situation of MDD treatment in clinical practice and compared the treatment based on the severity of MDD. Read More

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The occurrence of catatonia diagnosis in acute care hospitals in the United States: A national inpatient sample analysis.

Gen Hosp Psychiatry 2022 Jul-Aug;77:141-146. Epub 2022 May 24.

Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.

Objective: Catatonia is a neuropsychiatric disorder that can occur in the setting of many illnesses, but the frequency of catatonia diagnosis among hospitalized patients is poorly characterized. This study reports the occurrence of catatonia diagnosis among acute care hospital discharges in the United States and the cooccurring diagnoses of these patients.

Method: The National Inpatient Sample, an all-payors database of acute care hospital discharges, was queried for patients older than 18 discharged with a diagnosis of catatonia in 2019. Read More

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Risk of relapse within 6 months associated with borderline personality disorder in major depressed individuals treated with electroconvulsive therapy.

Psychiatry Res 2022 May 26;314:114650. Epub 2022 May 26.

Erasme Hospital, Department of Psychiatry and Sleep Laboratory, Université libre de Bruxelles, ULB, Brussels, Belgium, Route de Lennik, 808, Anderlecht 1070, Belgium.

Given the limited data in the literature, the aim of this study was to investigate the risk of relapse within 6 months associated with borderline personality disorder (BPD) in major depressed individuals treated with electroconvulsive therapy. Demographic and clinical data from 109 major depressed individuals with partial or complete response to electroconvulsive therapy recruited from the database of the Psychiatry Department of Erasme Hospital were analysed. Cox regression analyses were used to determine the risk of relapse within 6 months associated with BPD in major depressed individuals treated with electroconvulsive therapy. Read More

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Electroconvulsive Therapy: A Closer Look into Legal Provisions in the MHCA, 2017.

Indian J Psychol Med 2022 May 1;44(3):293-296. Epub 2022 May 1.

Dept. of Psychiatry, Neuropsychiatry Center, Gaya, Bihar, India.

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The Impact of Electroconvulsive Therapy on Negative Symptoms in Schizophrenia and Their Association with Clinical Outcomes.

Brain Sci 2022 Apr 25;12(5). Epub 2022 Apr 25.

Department of Mood Disorder and Anxiety, Institute of Mental Health, Singapore 539747, Singapore.

Objective: The treatment efficacy of electroconvulsive therapy (ECT) for negative symptoms amongst patients with schizophrenia remains unclear. In this study, we aim to examine the effects of ECT on negative symptoms in schizophrenia and their association with other clinical outcomes, including cognition and function.

Methods: This is a retrospective data analysis of patients with schizophrenia/schizoaffective disorder treated with ECT at the Institute of Mental Health (IMH), Singapore, between January 2016 and December 2019. Read More

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Electroconvulsive Treatment Utilization for Inpatient Management of Catatonia in Adolescents With Schizophrenia Spectrum Disorders.

J ECT 2022 May 25. Epub 2022 May 25.

Department of Psychiatry, The Ohio State University College of Medicine, Columbus, OH.

Objective: The aim of this study was to determine rates of electroconvulsive therapy (ECT) use for catatonia in schizophrenia spectrum disorders, stratified by patient demographics and hospital characteristics, and its impact on inpatient length of stay and cost.

Methods: We found 155 adolescents (aged 12-18 years) with principal discharge diagnosis of schizophrenia spectrum disorders with catatonia from the National Inpatient Sample. They were subgrouped into ECT (n = 20) and non-ECT (n = 135) groups. Read More

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Focal points of preanesthesia evaluations for electroconvulsive therapy in patients with depression: a retrospective analysis of clinical characteristics in nonremission.

BMC Anesthesiol 2022 May 26;22(1):163. Epub 2022 May 26.

Department of Anesthesiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.

Background: This study explored the patient clinical characteristics that may affect electroconvulsive therapy (ECT) efficacy to enable improved focus during evaluations and preparation for ECT.

Methods: Patients were enrolled for ECT at the Department of Psychiatry and Anesthesiology of the First Affiliated Hospital of Chongqing Medical University from December 2017 to January 2019. The primary outcome in our study was defined as the development of nonremission. Read More

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Accelerated Repetitive Transcranial Magnetic Stimulation in the Treatment of Negative Symptoms of Schizophrenia: An Open-Label Study.

J ECT 2022 Jun;38(2):e24-e25

Department of Psychiatry, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic

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