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    Electrical cardiac injuries: current concepts and management.
    Eur Heart J 2017 Apr 20. Epub 2017 Apr 20.
    Cardiology Department, European Georges Pompidou Hospital, 20 rue Leblanc, 75015 Paris, France.
    Electrical injuries are a commonly encountered hazard in both the home and workplace. However, clinicians are often uncomfortable when faced with the patient who presents with an electric shock due to sparse literature and lack of systematic recommendations on this topic. Electrical injuries can range from minor skin burns to life threatening internal organ damage. Read More

    Bilateral Asymmetrical Fracture Dislocation of Shoulder with Rare Combination of Injuries after Epileptic Seizure: A Case Report.
    Malays Orthop J 2017 Mar;11(1):74-76
    Department of Orthopaedics, Government Multispecialty Hospital, Chandigarh, India.
    The incidence of bilateral gleno-humeral joint dislocation is rare, is almost always posterior and is usually caused by sports injuries, epileptic seizures, electrical shock, or electroconvulsive therapy. Bilateral fracture-dislocation is even rarer, with a few cases reported in the literature. We report an unusual case with dislocation of the both glenohumeral joints in opposite direction after a seizure episode, with fracture of greater tuberosity on one side and of the lesser tuberosity on the contralateral side. Read More

    The occurrence of single and multiple organ dysfunction in pediatric electrical versus other thermal burns.
    J Trauma Acute Care Surg 2017 May;82(5):946-951
    From the Department of Surgery (G.H., P.W., C.V., J.C-D., C.C.F., D.N.H., L.K.B.), University of Texas Medical Branch, Galveston, Texas; Shriners Hospitals for Children-Galveston, Galveston, Texas (G.H., P.W., C.V., J.C-D., C.C.F., D.N.H., L.K.B.); Division of Plastic, Aesthetic and Reconstructive Surgery, Department of Surgery (P.W., J.C-D.), Medical University of Graz, Graz, Austria; Sealy Center for Molecular Medicine and the Institute for Translational Sciences, University of Texas Medical Branch, Galveston, Texas (C.C.F.); and School of Medicine, University of Texas Medical Branch, Galveston, Texas (A.F., V.C.).
    Background: Multiple organ failure (MOF) is a major contributor to morbidity and mortality in burned children. While various complications induced by electrical injuries have been described, the incidence and severity of single organ failure (SOF) and MOF associated with this type of injury are unknown. The study was undertaken to compare the incidence and severity of SOF and MOF as well as other complications between electrically and thermally burned children. Read More

    Effect of electrical stunning frequency and current waveform in poultry welfare and meat quality.
    Poult Sci 2017 Apr 17. Epub 2017 Apr 17.
    This study aimed to evaluate the effects of different stunning frequencies and electrical current waveforms on chicken welfare and meat quality. Two-hundred-thirty-two Cobb broilers, 48 d of age and 2.76 ± 0. Read More

    Patterns of Brachial Plexus Stretch Palsy in a Prospective Series of 565 Surgically Treated Patients.
    J Hand Surg Am 2017 Apr 12. Epub 2017 Apr 12.
    Pediatric Hand Surgery and Microsurgery Unit, Hospital Sant Joan de Deu, Universitat de Barcelona, Barcelona, Spain. Electronic address:
    Purpose: To report the distribution of the different patterns of stretch brachial plexus injuries (BPIs) in a retrospective cohort of patients operated at our institution during an 11-year period.

    Methods: From September 2002 to June 2012, we evaluated and operated on 565 patients with traction injuries of the brachial plexus. Average age was 26. Read More

    An engineered multiphase 3D microenvironment to ensure the controlled delivery of cyclic strain and hGDF-5 for the tenogenic commitment of hBMSCs.
    Tissue Eng Part A 2017 Apr 12. Epub 2017 Apr 12.
    University of Salerno, Department of Medicine and Surgery, Via S. Allende, 84081 Baronissi (SA), Italy ;
    At present, injuries or rupture of tendons are treated by surgical repair or conservative approaches with unpredictable clinical outcome. Alternative strategies to repair tendon defects without the undesirable side effects associated with the current options are needed. With this in mind, a tissue engineering approach has gained considerable attention as a promising strategy. Read More

    Different sequelae of electrical brain injury - MRI patterns.
    Burns 2017 Apr 8. Epub 2017 Apr 8.
    Section of Neuroradiology, Trauma Center Murnau, Germany. Electronic address:
    Purpose: Electrical injury to the central nervous system may lead to neurologic compromise via pleiotropic mechanisms. It may cause current-related, thermal or nonthermal damage followed by secondary mechanisms.

    Methods: We herein report a case of a 20-year old man, who experienced a low-voltage electric injury due to an occupational accident. Read More

    A Three-Dimensional Computational Human Head Model That Captures Live Human Brain Dynamics.
    J Neurotrauma 2017 Apr 10. Epub 2017 Apr 10.
    4 Department of Electrical and Computer Engineering, Johns Hopkins University , Baltimore, Maryland.
    Diffuse axonal injury (DAI) is a debilitating consequence of traumatic brain injury (TBI) attributed to abnormal stretching of axons caused by blunt head trauma or acceleration of the head. We developed an anatomically accurate, subject-specific, three-dimensional (3D) computational model of the human brain, and used it to study the dynamic deformations in the substructures of the brain when the head is subjected to rotational accelerations. The computational head models use anatomy and morphology of the white matter fibers obtained using MRI. Read More

    Fascicular nerve stimulation and recording using a novel double-aisle regenerative electrode.
    J Neural Eng 2017 Apr 6. Epub 2017 Apr 6.
    Institute of Neuroscience,Universidad Autonoma de Barcelona, Ed M, Campus UAB, Bellaterra, Barcelona, 08193,SPAIN.
    Objective: As artificial prostheses become more refined, they are most often used as a therapeutic option for hand amputation. Differently from extra- or intraneural interfaces, regenerative nerve electrodes are designed to enable electrical interface with regrowing axonal bundles of injured nerves, aiming to achieve high selectivity for recording and stimulation. However, most of the developed designs pose an obstacle to the regrowth mechanisms due to low transparency and cause an impairment of the nerve regeneration. Read More

    Comparison of Transcutaneous Electrical Nerve Stimulation and Lidocaine on Episiotomy Complication in Primiparous Women: A Randomized Clinical Trial.
    Iran J Nurs Midwifery Res 2017 Jan-Feb;22(1):26-30
    Psychosocial Injuries Research Center, Faculty of Nursing and Midwifery, Ilam University of Medical Sciences, Ilam, Iran.
    Introduction: Transcutaneous electrical nerve stimulation (TENS) through the skin is a nonpharmacological method of pain relief. The present study aimed to compare TENS and lidocaine on episiotomy complication in primiparous women.

    Material And Methods: In a randomized, controlled clinical trial, 80 participants were included from March to July 2011 at the antenatal clinic and postdelivery ward in the Social Security Organization Hospital, Khorramabad, Lorestan, Iran. Read More

    In search of evidence for the experience of pain in honeybees: A self-administration study.
    Sci Rep 2017 Apr 4;7:45825. Epub 2017 Apr 4.
    The Queensland Brain Institute, University of Queensland, Brisbane QLD 4072, Australia.
    Despite their common use as model organisms in scientific experiments, pain and suffering in insects remains controversial and poorly understood. Here we explore potential pain experience in honeybees (Apis mellifera) by testing the self-administration of an analgesic drug. Foragers were subjected to two different types of injuries: (i) a clip that applied continuous pressure to one leg and (ii) amputation of one tarsus. Read More

    Bi-layer Silk Fibroin Grafts Support Functional Esophageal Repair in a Rodent Model of Caustic Injury.
    J Tissue Eng Regen Med 2017 Mar 30. Epub 2017 Mar 30.
    Urological Diseases Research Center, Boston Children's Hospital, Boston, MA, USA.
    Surgical repair of caustic esophageal injuries with autologous gastrointestinal segments is often associated with dysmotility, dysphagia, and donor site morbidity and therefore alternative graft options are needed. Bi-layer silk fibroin (BLSF) scaffolds were assessed for their ability to support functional restoration of damaged esophageal tissues in a rat model of onlay esophagoplasty. Transient exposure of isolated esophageal segments with 40% NaOH led to corrosive esophagitis and a 91% reduction in the luminal cross-sectional area of damaged sites. Read More

    Detecting destabilizing wheelchair conditions for maintaining seated posture.
    Disabil Rehabil Assist Technol 2017 Apr 1:1-8. Epub 2017 Apr 1.
    a Motion Study Laboratory, Louis Stokes Cleveland, Affairs Medical Center , Cleveland , OH , USA.
    Purpose: The purpose of this study was to detect and classify potentially destabilizing conditions encountered by manual wheelchair users with spinal cord injuries (SCI) to dynamically increase stability and prevent falls.

    Methods: A volunteer with motor complete T11 paraplegia repeatedly propelled his manual wheelchair over level ground and simulated destabilizing conditions including sudden stops, bumps and rough terrain. Wireless inertial measurement units attached to the wheelchair frame and his sternum recorded associated accelerations and angular velocities. Read More

    A 3-Phase Approach for the Management of Upper Extremity Electrical Injuries.
    Hand Clin 2017 May 21;33(2):243-256. Epub 2017 Feb 21.
    Hand Fellowship, Division of Plastic and Reconstructive Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8238, St Louis, MO 63110, USA. Electronic address:
    Upper extremity electrical injuries present with unique pathophysiologic considerations due to the differing mechanisms of injury produced by the electromagnetic field. The initial phase of treatment consists of recognition of other life-threatening injuries, stabilization of patients, and multisystem resuscitation. The second phase of treatment consists of excising devitalized tissue, appropriate wound care to prevent delayed infection, providing temporary and definitive coverage over vital structures, and preventing contracture and joint stiffness via aggressive therapy. Read More

    Soft Tissue Reconstruction of Complete Circumferential Defects of the Upper Extremity.
    Arch Plast Surg 2017 Mar 15;44(2):117-123. Epub 2017 Mar 15.
    Division of Plastic Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
    Background: Upper extremity soft tissue defects with complete circumferential involvement are not common. Coupled with the unique anatomy of the upper extremity, the underlying etiology of such circumferential soft tissue defects represent additional reconstructive challenges that require treatment to be tailored to both the patient and the wound. The aim of this study is to review the various options for soft tissue reconstruction of complete circumferential defects in the upper extremity. Read More

    Lifetime risk of mortality due to different levels of alcohol consumption in seven European countries: implications for low-risk drinking guidelines.
    Addiction 2017 Mar 20. Epub 2017 Mar 20.
    Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, Toronto, Canada.
    Background And Aims: Low-risk alcohol drinking guidelines require a scientific basis that extends beyond individual or group judgements of risk. Lifetime mortality risks, judged against established thresholds for acceptable risk, may provide such a basis for guidelines. Therefore, the aim of this study was to estimate alcohol mortality risks for seven European countries based on different average daily alcohol consumption amounts. Read More

    Pattern of high voltage electrical injuries in the Kashmir valley: a 10-year single centre experience.
    Ann Burns Fire Disasters 2016 Dec;29(4):259-263
    Department of Plastic Surgery, SKIMS, Srinagar, Kashmir, India.
    The objective was to study the clinical profile of high voltage electrical injuries in Kashmir, and various prevention and safety measures to bring down the incidence of such injuries in the future. All patients (176) with high voltage electrical injuries reporting to our centre from January 2001 to December 2010 were included in the study. The most common age group was 20-40 years, with mean age of 29. Read More

    Saving the On-Scene Time for Out-of-Hospital Cardiac Arrest Patients: The Registered Nurses' Role and Performance in Emergency Medical Service Teams.
    Biomed Res Int 2017 9;2017:5326962. Epub 2017 Feb 9.
    Research Center for Soil & Water Resources and Natural Disaster Prevention (SWAN), National Yunlin University of Science & Technology, 123 Section 3, University Road, Douliou, Yunlin 640, Taiwan; Department and Graduate School of Safety and Environment Engineering, National Yunlin University of Science & Technology, 123 Section 3, University Road, Douliou, Yunlin 640, Taiwan.
    For out-of-hospital cardiac arrest (OHCA) patients, every second is vital for their life. Shortening the prehospital time is a challenge to emergency medical service (EMS) experts. This study focuses on the on-scene time evaluation of the registered nurses (RNs) participating in already existing EMS teams, in order to explore their role and performance in different EMS cases. Read More

    Effect of Laser Acupuncture on Heart Rate Variability of Nonpatients and Patients with Spinal Cord Injury.
    J Acupunct Meridian Stud 2017 Jan 29;10(1):53-54. Epub 2016 Nov 29.
    Health Science Unit (PEC), Hong Kong Physically Handicapped & Able Bodied Association, Sham Shui Po, Kowloon, Hong Kong. Electronic address:
    Sensory loss in a complete spinal cord injury (SCI) can be described as an injury that removes the ability of the brain to receive electrical afferent signals generated below the site of the injury. The sensory nervous system appears to be the same as the meridians in the concept of Oriental medicine, thus, we assumed that a complete SCI would lead to discontinuation of the meridians in humans. In this case series report with a cross-sectional view, we observed quantitative changes in heart rate variability induced by laser acupuncture at bilateral GB34 and ST36 points for 15 minutes in eight patients with complete SCIs between the levels of T8 and T12, and eight healthy individuals as a control group. Read More

    Guideline Implementation: Energy-Generating Devices, Part 1-Electrosurgery.
    AORN J 2017 Mar;105(3):300-310
    Energy-generating devices are standard equipment in the surgical suite, with electrosurgical units being the most common type of electrical device used in the OR. Prevention of injuries to patients and personnel related to the use of energy-generating devices is a key component of the perioperative nurse's role. The AORN "Guideline for safe use of energy-generating devices" provides guidance on the use and maintenance of devices that deliver energy in the forms of radiofrequency waves, ultrasound waves, or lasers. Read More

    Afferent electrical stimulation during cycling improves spinal processing of sensorimotor function after incomplete spinal cord injury.
    NeuroRehabilitation 2017 Feb 10. Epub 2017 Feb 10.
    Sensorimotor Function Group, Hospital Nacional de Parapléjicos, Toledo, Spain.
    Objective: Appropriate afferent feedback delivery during the execution of motor tasks is important for rehabilitation after incomplete spinal cord injury (iSCI). However, during leg-cycling therapy, the plantar afferent feedback is minimal. We hypothesize that the augmentation of sensory input by combining cycling with a locomotor-like stimulation of plantar cutaneous innervations (ES-cycling), might help to restore proper spinal processing of sensorimotor function. Read More

    Determinants of cough effectiveness in patients with respiratory muscle weakness.
    Respir Physiol Neurobiol 2017 Jun 16;240:17-25. Epub 2017 Feb 16.
    Loyola University of Chicago Stritch School of Medicine, Maywood, IL, United States; Hines Veterans Affairs Hospital, Hines, IL, United States. Electronic address:
    Experiments were undertaken to mechanistically define expiratory-muscle contribution to effectiveness of cough while controlling glottic movement. We hypothesized that electrical abdominal-muscle stimulation in patients with respiratory-muscle weakness produces effective coughs only when glottic closure accompanies coughs. In ten spinal-cord-injury patients, esophago-gastric pressure and airflow were recorded during solicited-coughs, coughs augmented by abdominal-muscle stimulation, and passive open-glottis exhalations. Read More

    Real-Time Monitoring of Post-Surgical and Post-Traumatic Eye Injuries Using Multilayered Electrical Biosensor Chip.
    ACS Appl Mater Interfaces 2017 Mar 3;9(10):8609-8622. Epub 2017 Mar 3.
    Department of Surgery, University of Illinois College of Medicine , Urbana, Illinois 61801, United States.
    Lack of current techniques for the early monitoring of bleb leaks and other post-traumatic or post-surgical ocular injury has posed an unmet clinical need for the development of new techniques. Present evaluation techniques use either subjective or nonquantitative approaches. At present, there are no FDA approved ocular devices that can directly measure ascorbic acid (AA) concentration levels for both tear film (TF) and aqueous humor (AH) at point-of-care (POC) level. Read More

    Bone contusion progression from traumatic knee injury: association of rate of contusion resolution with injury severity.
    Open Access J Sports Med 2017 27;8:9-15. Epub 2017 Jan 27.
    Department of Orthopaedics and Sports Medicine, Duke University Medical School, Durham, NC, USA.
    Background: Bone contusions are frequently encountered in magnetic resonance imaging (MRI) evaluation of knee anterior cruciate ligament (ACL) injuries. Their role as indicators of injury severity remains unclear, primarily due to indeterminate levels of joint injury forces and to a lack of preinjury imaging.

    Purpose: The purpose of this study was to 1) quantify bone contusion pathogenesis following traumatic joint injuries using fixed imaging follow-ups, and 2) assess the feasibility of using longitudinal bone contusion volumes as an indicator of knee injury severity. Read More

    Clinical management of electrical burns in the developing world: a case of electrical burn injury left untreated leading to amputation.
    BMJ Case Rep 2017 02 15;2017. Epub 2017 Feb 15.
    Menzies Health Institute Queensland, Southport, Queensland, Australia.
    We discuss the case of a 26-year-old male patient from Northern Samar, the Philippines who was left without essential health services after the amputation of all four limbs following a high voltage (20 000 volts) injury in Metro Manila in 2011. Local health services in the developing world are faced with enormous challenges in providing first-line care for burn patients. The cost of maintaining a burn unit, finding suitable qualified staff, and appropriate referral mechanisms are only some of the challenges faced. Read More

    Application of a paraplegic gait orthosis in thoracolumbar spinal cord injury.
    Neural Regen Res 2016 Dec;11(12):1997-2003
    Department of Rehabilitation, the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, China.
    Paraplegic gait orthosis has been shown to help paraplegic patients stand and walk, although this method cannot be individualized for patients with different spinal cord injuries and functional recovery of the lower extremities. There is, however, a great need to develop individualized paraplegic orthosis to improve overall quality of life for paraplegic patients. In the present study, 36 spinal cord (below T4) injury patients were equally and randomly divided into control and observation groups. Read More

    Neurologic complications of acute environmental injuries.
    Handb Clin Neurol 2017 ;141:685-704
    Neurological Institute, Cleveland Clinic, Cleveland, OH, USA. Electronic address:
    Environmental injuries can result in serious neurologic morbidity. This chapter reviews neurologic complications of thermal burns, smoke inhalation, lightning strikes, electric injury, near drowning, decompression illness, as well as heat stroke and accidental hypothermia. Knowing the pathophysiology and clinical presentation of such injuries is essential to proper management of primary and secondary medical complications. Read More

    Lightning Injury is a disaster in Bangladesh? - Exploring its magnitude and public health needs.
    F1000Res 2016 29;5:2931. Epub 2016 Dec 29.
    Centre for Injury Prevention and Research, Bangladesh (CIPRB), Dhaka, Bangladesh.
    Background: Lightning injury is a global public health issue. Low and middle-income countries in the tropical and subtropical regions of the world are most affected by lightning. Bangladesh is one of the countries at particular risk, with a high number of devastating lightning injuries in the past years, causing high mortality and morbidity. Read More

    Low temperature plasma equipment applied on surgical hemostasis and wound healings.
    J Clin Biochem Nutr 2017 Jan 17;60(1):25-28. Epub 2016 Dec 17.
    Biotechnology Research Institute for Drug Discovery, National Institute of Advanced Industrial Science and Technology (AIST), Central 5-41, 1-1-1 Higashi, Tsukuba 305-8568, Japan; Electronics and Photonics Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Central 5-41, 1-1-1 Higashi, Tsukuba 305-8568, Japan; Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-0856, Japan.
    Low temperature plasma (LTP) coagulation equipment, which avoids causing burn injuries to patients, has been introducing into minimally invasive surgery. The mechanism by which this equipment stops bleeding is to directly occupy the injury with the formed blood clots, and different from the mechanism of the common electrical hemostatic devices that cauterize the tissues around the bleeding to stem the blood flow. A noteworthy point is that LTP treatment with our equipment is not confined only to the blood coagulation system, but it has significant effects on the other blood components to form clots with or without hemolysis, and that there is a plasma current threshold that determines whether the treatment makes stable clots. Read More

    [Repair mechanisms of the wounds with exposed bone structures using an artificial dermis].
    Zhonghua Yi Xue Za Zhi 2017 Jan;97(4):308-312
    Department of Burn and Plastic Surgery, Beijing Jishuitan Hospital, Beijing 100035, China.
    Objective: To investigate the repair mechanisms of the wounds with bone exposed by artificial dermis transplantation. Methods: Seventy two rabbits were randomly divided into 3 groups of 24 rabbits, the wound model was made on the top of head. In the skin defect group (SD group), skin was removed and skull periosteum was retained. Read More

    Cell and Growth Factor-Loaded Keratin Hydrogels for Treatment of Volumetric Muscle Loss in a Mouse Model.
    Tissue Eng Part A 2017 Apr 14. Epub 2017 Apr 14.
    2 Wake Forest Institute for Regenerative Medicine, Wake Forest University , Winston-Salem, North Carolina.
    Wounds to the head, neck, and extremities have been estimated to account for ∼84% of reported combat injuries to military personnel. Volumetric muscle loss (VML), defined as skeletal muscle injuries in which tissue loss results in permanent functional impairment, is common among these injuries. The present standard of care entails the use of muscle flap transfers, which suffer from the need for additional surgery when using autografts or the risk of rejection when cadaveric grafts are used. Read More

    Injuries among electric power industry workers, 1995-2013.
    J Safety Res 2017 Feb 25;60:9-16. Epub 2016 Nov 25.
    EPRI, 942 Corridor Park Blvd, Knoxville, TN 37932, United States.
    Introduction: Workers in the electric power industry face many risks of injury due to the high diversity of work tasks performed in potentially hazardous and unpredictable work environments.

    Method: We calculated injury rates by age, sex, occupational group, and injury type among workers in the Electric Power Research Institute's (EPRI) Occupational Health and Safety Database (OHSD), which contains recordable injury, medical claims, and personnel data from 18 participating electric power companies from 1995 to 2013.

    Results: The OHSD includes a total of 63,193 injuries over 1,977,436 employee-years of follow-up, for an overall injury rate of 3. Read More

    Late complications of high-voltage electrical injury might involve multiple systems and be related to current path.
    Ann Burns Fire Disasters 2016 Sep;29(3):192-194
    Department of Plastic and Maxillofacial Surgery, Uppsala University Hospital, Uppsala, Sweden.
    Delayed complications of electrical burns are mostly unexpected, and the link between the injury and the symptoms often goes unrecognized. A possible relation between source-ground sites and late clinical manifestations was recently emphasized. We report a unique case of combined intestinal-spinal delayed complications following a high-voltage electrical injury, a possible explanation being a greater current flow through the right hemisoma. Read More

    An experiment on rider stability while mounting: Comparing middle-aged and elderly cyclists on pedelecs and conventional bicycles.
    Accid Anal Prev 2017 Jan 24. Epub 2017 Jan 24.
    Engineering, Management & Education, The University of British Columbia, 1137 Alumni Ave, Kelowna BC V1 V 1V7, Canada. Electronic address:
    Pedelecs, popular among elderly cyclists, are associated with a higher injury risk than conventional bicycles. About 17% of these injuries are due to falls while (dis)mounting. Using instrumented bicycles, this study aimed to identify factors contributing to the stability of self-chosen mounting methods in four user groups: 30-45 versus 65+ years of age and males versus females. Read More

    Neurotological findings after electrical injury at the workplace.
    Laryngoscope 2017 Jan 24. Epub 2017 Jan 24.
    Department of Otolaryngology-Head and Neck Surgery, University Health Network, Toronto, Ontario, Canada.
    Objectives/hypothesis: Neurotological findings secondary to electrical injuries have rarely been reported in the world literature. We attempt to characterize the neurotological findings following electrical injury and to determine the role head injury and loss of consciousness play in this population's clinical presentation.

    Study Design: Retrospective cohort study. Read More

    An unusual case of simultaneous bilateral neck of femur fracture following electrocution injury-A case report and review of literature.
    J Orthop Case Rep 2016 Jul-Aug;6(3):70-72
    Department of Orthopaedics, JSS Hospital, Mysore, India.
    Introduction: Simultaneous bilateral fractures of the neck of femur is rare. Hypocalcemia, epilepsy, osteoporosis and electrical injuries are known to cause similar injuries.

    Case Report: We report a case of a 43-year-old male who sustained an electrical shock injury following which he fell from a height of around 4 feet. Read More

    A Mixed-Signal VLSI System for Producing Temporally Adapting Intraspinal Microstimulation Patterns for Locomotion.
    IEEE Trans Biomed Circuits Syst 2016 Mar 9. Epub 2016 Mar 9.
    Neural pathways can be artificially activated through the use of electrical stimulation. For individuals with a spinal cord injury, intraspinal microstimulation, using electrical currents on the order of 125 μ A, can produce muscle contractions and joint torques in the lower extremities suitable for restoring walking. The work presented here demonstrates an integrated circuit implementing a state-based control strategy where sensory feedback and intrinsic feed forward control shape the stimulation waveforms produced on-chip. Read More

    Relationship between non-standard work arrangements and work-related accident absence in Belgium.
    J Occup Health 2017 Mar 21;59(2):177-186. Epub 2017 Jan 21.
    Department of Electrical Energy, Systems and Automation, Faculty of Engineering and Architecture, Ghent University.
    Objectives: The main objective of this study is to examine the relationship between indicators of non-standard work arrangements, including precarious contract, long working hours, multiple jobs, shift work, and work-related accident absence, using a representative Belgian sample and considering several socio-demographic and work characteristics.

    Methods: This study was based on the data of the fifth European Working Conditions Survey (EWCS). For the analysis, the sample was restricted to 3343 respondents from Belgium who were all employed workers. Read More

    Clinically Relevant Levels of 4-Aminopyridine Strengthen Physiological Responses in Intact Motor Circuits in Rats, Especially After Pyramidal Tract Injury.
    Neurorehabil Neural Repair 2017 Apr 20;31(4):387-396. Epub 2017 Jan 20.
    1 Burke Medical Research Institute, White Plains, NY, USA.
    Background: 4-Aminopyridine (4-AP) is a Food and Drug Administration-approved drug to improve motor function in people with multiple sclerosis. Preliminary results suggest the drug may act on intact neural circuits and not just on demyelinated ones.

    Objective: To determine if 4-AP at clinically relevant levels alters the excitability of intact motor circuits. Read More

    A BCI-based Environmental Control System for Patients with Severe Spinal Cord Injuries.
    IEEE Trans Biomed Eng 2017 Jan 9. Epub 2017 Jan 9.
    This study proposes an event-related potential (ERP) BCI-based environmental control system that integrates household electrical appliances, a nursing bed, and an intelligent wheelchair to provide daily assistance to paralyzed patients with severe spinal cord injuries (SCIs).

    Methods: An asynchronous mode is used to switch the environmental control system on or off or to select a device (e.g. Read More

    Interplay between Cortical Spreading Depolarization and Seizures.
    Stereotact Funct Neurosurg 2017 14;95(1):1-5. Epub 2017 Jan 14.
    Department of Neurosurgery, University of Southern California, Los Angeles, CA, USA.
    Cortical spreading depolarization (CSD) is an electrophysiologic phenomenon found mostly in the setting of neurologic injury resulting in the disturbance of ion homeostasis and leading to changes in the local vascular response. The bioelectric etiology of CSD shares similarities to those in epileptic disorders, yet the relationship between seizures and CSD is unclear, with several studies observing cortical depression before, during, and after seizure activity, thus obscuring our understanding of whether CSD activity potentiates or limits seizures and vice versa. Cortical sampling has exhibited how the redistribution of ion concentrations in the intra- and extracellular environments interplay between the excitation of seizures and the electrical depression of CSD. Read More

    Pressure ulcer image segmentation technique through synthetic frequencies generation and contrast variation using toroidal geometry.
    Biomed Eng Online 2017 Jan 6;16(1). Epub 2017 Jan 6.
    DeustoTech - Fundación Deusto, Avda/Universidades 24, 48007, Bilbao, Spain.
    Background: Pressure ulcers have become subject of study in recent years due to the treatment high costs and decreased life quality from patients. These chronic wounds are related to the global life expectancy increment, being the geriatric and physical disable patients the principal affected by this condition. Injuries diagnosis and treatment usually takes weeks or even months by medical personel. Read More

    Measurement of electrocardiograms in a bath through tap water utilizing capacitive coupling electrodes placed outside the bathtub wall.
    Biomed Eng Online 2017 Jan 11;16(1):12. Epub 2017 Jan 11.
    NPO Research Institute of Life Benefit, 6-11-7-1 Sumikawa, Minami-ku, Sapporo, 005-0006, Japan.
    Background: Taking a bath sometimes poses a risk for subjects with chronic cardiopulmonary disorders, due to the thermal effect and water pressure on his/her body. The ECG measurement would be helpful for the early recognition of abnormal cardiac beats and respiratory conditions. This paper describes a new attempt to improve on previous bathtub ECG measurement techniques that had electrodes placed inside the bathtub that were intrusive to the subjects' bathing experience. Read More

    Hybrid brain-computer interface for biomedical cyber-physical system application using wireless embedded EEG systems.
    Biomed Eng Online 2017 Jan 7;16(1). Epub 2017 Jan 7.
    Centre for Health Technologies, Faculty of Engineering and Information Technology, University of Technology, Sydney, NSW, 2007, Australia.
    Background: One of the key challenges of the biomedical cyber-physical system is to combine cognitive neuroscience with the integration of physical systems to assist people with disabilities. Electroencephalography (EEG) has been explored as a non-invasive method of providing assistive technology by using brain electrical signals.

    Methods: This paper presents a unique prototype of a hybrid brain computer interface (BCI) which senses a combination classification of mental task, steady state visual evoked potential (SSVEP) and eyes closed detection using only two EEG channels. Read More

    Evaluation of PVA biodegradable electric conductive membranes for nerve regeneration in axonotmesis injuries: the rat sciatic nerve animal model.
    J Biomed Mater Res A 2017 May 13;105(5):1267-1280. Epub 2017 Feb 13.
    Departmento de Clínicas Veterinárias, Instituto de Ciências Biomédicas de Abel Salazar (ICBAS), Universidade do Porto (UP), Rua de Jorge Viterbo Ferreira, nº 228, Porto, 4050-313, Portugal.
    The therapeutic effect of three polyvinyl alcohol (PVA) membranes loaded with electrically conductive materials - carbon nanotubes (PVA-CNTs) and polypyrrole (PVA-PPy) - were tested in vivo for neuro-muscular regeneration after an axonotmesis injury in the rat sciatic nerve. The membranes electrical conductivity measured was 1.5 ± 0. Read More

    Electrical Stimulation to Reduce the Overload in Upper Limbs During Sitting Pivot Transfer in Paraplegic: A Preliminary Study.
    Eur J Transl Myol 2016 Sep 5;26(4):6223. Epub 2016 Aug 5.
    NTAAI, Faculdade de Ceilândia, Universidade de Brasília , Brasília, Brazi.
    Transfer is a key ability and allows greater interact with the environment and social participation. Conversely, paraplegics have great risk of pain and injury in the upper limbs due to joint overloads during activities of daily living, like transfer. The main goal of this study is to verify if the use of functional electrical stimulation (FES) in the lower limbs of paraplegic individuals can assist the sitting pivot transfer (SPT). Read More

    Trunk Motion System (TMS) Using Printed Body Worn Sensor (BWS) via Data Fusion Approach.
    Sensors (Basel) 2017 Jan 8;17(1). Epub 2017 Jan 8.
    Laboratory of Wearable Technologies and Neuromusculoskeletal Research, School of Mechanical Engineering, Sharif University of Technology, Tehran 11155-9567, Iran.
    Human movement analysis is an important part of biomechanics and rehabilitation, for which many measurement systems are introduced. Among these, wearable devices have substantial biomedical applications, primarily since they can be implemented both in indoor and outdoor applications. In this study, a Trunk Motion System (TMS) using printed Body-Worn Sensors (BWS) is designed and developed. Read More

    Swimming Pool Electrical Injuries: Steps Toward Prevention.
    Pediatr Emerg Care 2017 Jan 9. Epub 2017 Jan 9.
    From the *DeWitt-Daughtry Department of Surgery, Leonard M. Miller School of Medicine, University of Miami; and †Department of Pediatric Surgery, Nicklaus Children's Hospital, Miami, FL.
    Objective: Electrical injuries in swimming pools are an important pediatric public health concern. We sought to (1) improve our understanding of the clinical presentation and outcomes following and (2) describe the epidemiology of swimming pool electrical injuries in the United States.

    Methods: We reviewed 4 cases of pediatric (<18 y old) electrical injury from a single, urban level 1 pediatric trauma center. Read More

    The accuracy of burn diagnosis codes in health administrative data: A validation study.
    Burns 2017 Mar 6;43(2):258-264. Epub 2017 Jan 6.
    Sunnybrook Research Institute, Toronto, Canada; Ross Tilley Burn Centre, Sunnybrook Health Sciences Centre, Toronto, Canada; Institute of Medical Sciences, University of Toronto, Toronto, Canada.
    Background: Health administrative databases may provide rich sources of data for the study of outcomes following burn. We aimed to determine the accuracy of International Classification of Diseases diagnoses codes for burn in a population-based administrative database.

    Methods: Data from a regional burn center's clinical registry of patients admitted between 2006-2013 were linked to administrative databases. Read More

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