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Brain 2022 May 18. Epub 2022 May 18.

Brain Research Institute, University of Zurich, 8057 Zurich, Switzerland.

Severe spinal cord injuries result in permanent paraparesis in spite of the frequent sparing of small portions of white matter. Spared fiber tracts are often incapable of maintaining and modulating the activity of lower spinal motor centers. Effects of rehabilitative training thus remain limited. Read More

Ann Burns Fire Disasters 2022 Mar;35(1):18-25

Department of Plastic and Reconstructive Surgery, Hospital São José (Centro Hospitalar Lisboa Central), Lisbon, Portugal.

A great number of burns affect the hands, either as part of a more extensive burn or as an isolated injury. These injuries can lead to physical, social and psychological consequences that may reduce quality of life and make difficult the return to work. The goal of this study was to investigate the main epidemiologic characteristics of adult patients with hand burns admitted to a dedicated burn centre, evaluate the outcomes of the treatment, and identify the predictors associated with the worst outcomes. Read More

Arch Dis Child Educ Pract Ed 2022 May 17. Epub 2022 May 17.

Emergency Department, Temple Street Children's University Hospital, Dublin, Dublin, Ireland.

It's 21:00 and you receive a stand-by call from the local ambulance service. Peter, a 9-year-old boy, was riding an electric scooter and has collided with a car. He has reduced consciousness, signs of shock and is hypoxic. Read More

Sci Rep 2022 May 16;12(1):8044. Epub 2022 May 16.

Department of Electrical and Computer Engineering, University of Patras, 25500, Patras, Greece.

Anterior cruciate ligament (ACL) tear is one of the most common knee injuries. The ACL reconstruction surgery aims to restore healthy knee function by replacing the injured ligament with a graft. Proper selection of the optimal surgery parameters is a complex task. Read More

Cureus 2022 May 11;14(5):e24904. Epub 2022 May 11.

Department of Research, Rinaldi Fontani Foundation, Florence, ITA.

Cells and tissues work like batteries, positively charged by potassium ions and negatively charged by chloride ions. The difference in potential gradient generates an ionic flux, and this, in turn, generates a current that develops endogenous bioelectric fields (EBFs), which are fundamental for all cellular life processes, including reparative phenomena. In damaged tissues, the ionic flow is altered and, consequently, the production of EBFs is altered. Read More

NeuroRehabilitation 2022 May 9. Epub 2022 May 9.

Rehabilitation Unit, ULSS (Local Health Authority) Euganea - Camposampiero Hospital, Padova, Italy.

Background: Gait impairments are common disabling symptoms of Parkinson's disease (PD). Among the approaches for gait rehabilitation, interest in robotic devices has grown in recent years. However, the effectiveness compared to other interventions, the optimum amount of training, the type of device, and which patients might benefit most remains unclear. Read More

Int J Environ Res Public Health 2022 Apr 24;19(9). Epub 2022 Apr 24.

The Second Affiliated Hospital of Shantou University Medical College, Shantou 515000, China.

The Electric Bike (EB) has become an ideal mode of transportation because of its simple operation, convenience, and because it is time saving, economical and environmentally friendly. However, electric bicycle road-traffic injuries (ERTIs) have become a road-traffic safety problem that needs to be solved urgently, bringing a huge burden to public health. In order to provide basic data and a theoretical basis for the prevention and control of ERTIs in Shantou, mixed research combining a case-control study and a case-crossover study was carried out to investigate the cycling behavior characteristics and injury status of EB riders in Shantou city, and to explore the influencing factors of ERTI. Read More

Forensic Sci Med Pathol 2022 May 13. Epub 2022 May 13.

Department of Health Surveillance and Bioethics, Fondazione Policlinico A. Gemelli IRCCS, Università Cattolica del Sacro Cuore Largo F. Vito, 00168, Rome, Italy.

Nowadays, one of the most important health and social policy issues concerning all countries is the problem of road accident rates. Traffic is one of the most important risk factors. For this reason, ridesharing companies have been launching electric scooters in Rome since June 2019 with the aim of reducing car traffic. Read More

Fluids Barriers CNS 2022 May 12;19(1):33. Epub 2022 May 12.

Institute for Nanobiotechnology, Johns Hopkins University, 100 Croft Hall, 3400 North Charles Street, Baltimore, MD, USA.

Oxidative stress is a shared pathology of neurodegenerative disease and brain injuries, and is derived from perturbations to normal cell processes by aging or environmental factors such as UV exposure and air pollution. As oxidative cues are often present in systemic circulation, the blood-brain barrier (BBB) plays a key role in mediating the effect of these cues on brain dysfunction. Therefore, oxidative damage and disruption of the BBB is an emergent focus of neurodegenerative disease etiology and progression. Read More

J Photochem Photobiol B 2022 May 2;232:112460. Epub 2022 May 2.

Radiation Sciences Research Center, Laser Research Center in Medical Sciences, Aja University of Medical Sciences, Tehran, Iran; International Network for Photo Medicine and Photo Dynamic Therapy (INPMPDT), Universal Scientific Education and Research Network (USERN), Tehran, Iran. Electronic address:

Introduction: There is a possibility of neurotmesis of the inferior alveolar nerve (IAN) in mandibular fractures, which leads to neurosensory impairment. In this study, we aimed to investigate the efficacy of photobiomodulation therapy (PBMT) in patients with neurotmesis following trauma and mandibular fracture.

Materials And Methods: This triple-blind randomized trial was carried out on patients who suffered neurotmesis of the IAN following mandibular angle and body fracture at least for 6 months. Read More

Sci Rep 2022 May 11;12(1):7733. Epub 2022 May 11.

Neurosurgery Department, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA.

Spinal cord stimulation enhanced restoration of motor function following spinal cord injury (SCI) in unblinded studies. To determine whether training combined with transcutaneous electrical spinal cord stimulation (tSCS), with or without systemic serotonergic treatment with buspirone (busp), could improve hand function in individuals with severe hand paralysis following SCI, we assessed ten subjects in a double-blind, sham-controlled, crossover study. All treatments-busp, tSCS, and the busp plus tSCS-reduced muscle tone and spasm frequency. Read More

J Oral Maxillofac Surg 2022 Apr 6. Epub 2022 Apr 6.

Senior scientist, Principal investigator, Department of Trauma Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; Senior scientist, Emergency Care Network Northern Netherlands (AZNN), Northern Netherlands Trauma Registry, The Netherlands.

Purpose: With the increased use of both e-bike and conventional bicycle, the number of bicycle-related accidents has increased accordingly. To determine whether there are differences in maxillofacial injuries between these 2 types of bicycle accidents, e-bike and conventional bicycle accidents were compared.

Material And Methods: A retrospective cohort study was conducted for all the consecutive patients with maxillofacial injury due to e-bike and conventional bicycle accidents attending the emergency department of 4 hospitals in the Netherlands between May 2018 and October 2019. Read More

Phytomedicine 2022 Jul 26;101:154131. Epub 2022 Apr 26.

School of Pharmaceutical, Guangzhou University of Chinese Medicine, No. 232 Waihuan Dong Rd., Guangzhou University Town, Panyu District, Guangzhou, 510000, China. Electronic address:

Background: Berberine has received rising attention for its application in cardiovascular disease because of its relationship with inflammation. The endothelial NLRP3 inflammasome triggers inflammatory vascular injury which would lead to cardiovascular disease. Endothelial calcium signalling plays a crucial role in both the activation of NLRP3 inflammasome and endothelial cells dysfunction. Read More

Neural Plast 2022 29;2022:3593262. Epub 2022 Apr 29.

Department of Biomedical Engineering, National Cheng Kung University, Tainan 701, Taiwan.

Background: Various forms of theta-burst stimulation (TBS) such as intermittent TBS (iTBS) and continuous TBS (cTBS) have been introduced as novel facilitation/suppression schemes during repetitive transcranial magnetic stimulation (rTMS), demonstrating a better efficacy than conventional paradigms. Herein, we extended the rTMS-TBS schemes to electrical stimulation of high-definition montage (HD-TBS) and investigated its neural effects on the human brain.

Methods: In a within-subject design, fifteen right-handed healthy adults randomly participated in 10 min and 2 mA HD-TBS sessions: unilateral (Uni)-iTBS, bilateral (Bi)-cTBS/iTBS, and sham stimulation over primary motor cortex regions. Read More

J Neuroeng Rehabil 2022 May 8;19(1):45. Epub 2022 May 8.

School of Information Technology and Electrical Engineering, The University of Queensland, Brisbane, Australia.

Background: In this work, we share the enhancements made in our system to take part in the CYBATHLON 2020 Global Edition Functional Electrical Stimulation (FES) Bike Race. Among the main improvements, firstly an overhaul, an overhaul of the system and user interface developed with User-centered design principles with remote access to enable telerehabilitation. Secondly, the implementation and experimental comparison between the traditional single electrode stimulation (SES) and spatially distributed sequential stimulation (SDSS) applied for FES Cycling. Read More

Int J Legal Med 2022 May 7. Epub 2022 May 7.

Department of Pharmacology, Inonu University Faculty of Medicine, Malatya, Turkey.

It is difficult to determine the cause of death in electric shock injuries when no trace can be determined on the skin, and this is accepted as a reason for negative autopsy. We aimed to determine useful parameters in the definition of the cause of deaths associated with electric shock and particularly those formed with water conduction. This study used a total of 42 rats, applied with fatal electric shock formed of isolated electric shock at 220 V and with water conduction. Read More

Inj Prev 2022 May 6. Epub 2022 May 6.

Department of Farm Machinery and Power Engineering, Punjab Agricultural University, Ludhiana, India.

Objective: Analysis of data on monetary compensation and estimating the rate of injuries related to agricultural activities in the state of Punjab.

Methods: The primary data were collected from 22 districts of Punjab state for 2012-2015 through Punjab State Agricultural Marketing Board, Mohali. Data were analysed for the nature of health hazards, type of injuries, possible causes and factors of injuries and their gender. Read More

Top Spinal Cord Inj Rehabil 2022 12;28(2):176-184. Epub 2022 Apr 12.

School of Kinesiology, California State University, Los Angeles.

Background: The influence of exercise after spinal cord injury (SCI) is a topic important to both clinicians and researchers. The impact of exercise for individuals with SCI is often studied quantitively, with a large focus on the physiological adaptations to exercise intervention.

Objectives: This study explores individualized experiences of exercise for people with SCI. Read More

Top Spinal Cord Inj Rehabil 2022 14;28(2):139-152. Epub 2022 Jan 14.

Department of Physical Therapy, Craig Hospital, Englewood, Colorado.

Objectives: To evaluate upper extremity (UE) function, strength, and dynamic sitting balance in individuals with spinal cord injury (SCI) who received an intensive outpatient therapy program focused on UE training augmented with wide pulse/high frequency functional electrical stimulation (WPHF-FES).

Methods: This prospective case series was conducted in an outpatient (OP) clinic in an SCI-specific rehabilitation hospital. Participants were a convenience sample ( = 50) of individuals with tetraplegia receiving OP therapy focused on UE recovery. Read More

J Orthop 2022 May-Jun;31:86-91. Epub 2022 Apr 15.

University of Miami, Jackson Memorial Hospital, Department of Orthopedics, Miami, FL, USA.

Introduction: Electric scooter rentals are offered by major ridesharing companies as a new and alternative method for urban travel in major metropolitan areas. The correlation between motorized electric scooter rental services and orthopedic injuries has not been well scrutinized. The purpose of our study is to evaluate orthopedic injuries sustained by motorized scooter riders and their potential correlation with patient demographics and associated injuries. Read More

Int J Biol Macromol 2022 Jun 27;209(Pt B):1867-1881. Epub 2022 Apr 27.

Key Laboratory of Eco-Textiles, Ministry of Education, College of Textile Science and Engineering, Jiangnan University, Wuxi, Jiangsu 214122, PR China; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Nantong University, Nantong, Jiangsu 226001, PR China; Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu 226001, PR China. Electronic address:

The composition and spatial structure of bioscaffold materials are essential for constructing tissue regeneration microenvironments. In this study, by using an electrospinning technique without any other additives, we successfully developed pure porcine decellularized nerve matrix (xDNME) conduits. The developed xDNME was composed of an obvious decellularized matrix fiber structure and effectively retained the natural components in the decellularized matrix of the nerve tissue. Read More

J Med Biogr 2022 Apr 28:9677720221097793. Epub 2022 Apr 28.

Italian Society of History of Medicine, Italy.

Vittorio Maragliano was born in Genoa in 1878. Fascinated since childhood by all things electric, he succeeded in installing the first radiological apparatus in 1896, only one year after the discovery of "Röntgen rays", and immediately began to make his first radioscopy observations. Having graduated from the University of Genoa in 1901 with a thesis on high-frequency currents, he continued assiduously to frequent the Department of Electrotherapy of the Medical Clinic, where he immediately became an assistant. Read More

Comput Methods Biomech Biomed Engin 2022 Apr 28:1-24. Epub 2022 Apr 28.

Key Laboratory of Forensic Science, Ministry of Justice, China (Academy of Forensic Science), Shanghai, China.

Skull fracture and brain injury are frequent head injuries in electric two-wheeler (ETW) accidents, and the type of helmet and impact conditions affect the effectiveness of the helmet in protecting the rider's head. The purpose of this study was to conduct in-depth reconstructions of rider's head-to-ground impacts in ten ETW accidents by using a multi-body system combined with a finite element approach and to evaluate the effect of two typical full-face helmets (FFH) and one half-coverage helmet (HCH) through head accelerations and intracranial biomechanics injury metrics in ground impacts. The results showed that all three helmets reduced the risk of skull fracture in most cases, however, FFH performed better due to its wider protection area. Read More

Front Med Technol 2022 5;4:859498. Epub 2022 Apr 5.

Ångström Laboratory, Department of Engineering Sciences, Microwaves in Medical Engineering Group, Solid State Electronics, Uppsala University, Uppsala, Sweden.

The European "Senseburn" project aims to develop a smart, portable, non-invasive microwave early effective diagnostic tool to assess the depth(d) and degree of burn. The objective of the work is to design and develop a convenient non-invasive microwave sensor for the analysis of the burn degree on burnt human skin. The flexible and biocompatible microwave sensor is developed using a magnetically coupled loop probe with a spiral resonator (SR). Read More

Case Rep Ophthalmol Med 2022 16;2022:3699667. Epub 2022 Apr 16.

Eye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Purpose: To report a case of central retinal vein occlusion (CRVO) and paracentral acute middle maculopathy (PAMM) following electric shock injury. . A 45-year-old male presented with a significant painless decreased vision in the right eye following an electrical injury of the right hand in his workplace. Read More

Br Dent J 2022 04 22;232(8):535-537. Epub 2022 Apr 22.

Oral and Maxillofacial Surgery Department, King´s College Hospital, Denmark Hill, London, SE5 9RS, UK; King´s College London, University of London, UK.

Introduction Electric scooters (e-scooters) are rife but are yet to be legalised in the UK. The aim of this paper was to investigate whether there had been an increase in the number of e-scooter injuries referred to the oral and maxillofacial surgery (OMFS) service at our unit. We present here what is, to our knowledge, the largest dataset regarding e-scooter-related injuries in the UK. Read More

Sensors (Basel) 2022 Apr 14;22(8). Epub 2022 Apr 14.

Roessingh Research and Development, 7522 AH Enschede, The Netherlands.

Physical exercise (PE) is beneficial for both physical and psychological health aspects. However, excessive training can lead to physical fatigue and an increased risk of lower limb injuries. In order to tailor training loads and durations to the needs and capacities of an individual, physical fatigue must be estimated. Read More

Biology (Basel) 2022 Apr 14;11(4). Epub 2022 Apr 14.

Department of Sports Medicine, University of Wuppertal, Moritzstraße 14, 42117 Wuppertal, Germany.

Electromyostimulation has been shown to intensify exercise when superimposed on cycling. However, little is known about the application during running, which might help to prevent injuries linked to high running volumes, as intensification of running allows for a reduction in training volume. Therefore, the purpose of the study was to examine the effects of electromyostimulation superimposed on running. Read More

Biomedicines 2022 Apr 7;10(4). Epub 2022 Apr 7.

Center for Neuroscience, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Korea.

Traumatic brain injury (TBI) leads to long-term cognitive impairments, with an increased risk for neurodegenerative and psychiatric disorders. Among these various impairments, olfactory dysfunction is one of the most common symptoms in TBI patients. However, there are very few studies that show the association between olfactory dysfunction and repetitive TBI. Read More

Nursing 2022 May;52(5):39-43

Kyle McCollum is a clinical manager for the Chicago Electrical Trauma Research Institute, where T.R. Gowrishankar is a senior research engineer and Raphael C. Lee is the chairman. Lee is also a professor at the University of Chicago.

Abstract: The clinical spectrum of electrical injury ranges from the absence of any external physical signs to severe and life-threatening trauma. This article discusses the fundamental concepts and misunderstandings surrounding electrical injuries and the best practices for evaluation and treatment. Read More