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    Fractal dimension brain morphometry: a novel approach to quantify white matter in traumatic brain injury.
    Brain Imaging Behav 2018 Jun 16. Epub 2018 Jun 16.
    Department of Physical Medicine and Rehabilitation, Rutgers New Jersey Medical School, Rutgers, the State University of New Jersey, Newark, NJ, 07103, USA.
    Traumatic brain injury (TBI) is the main cause of disability in people younger than 35 in the United States. The mechanisms of TBI are complex resulting in both focal and diffuse brain damage. Fractal dimension (FD) is a measure that can characterize morphometric complexity and variability of brain structure especially white matter (WM) structure and may provide novel insights into the injuries evident following TBI. Read More

    Virtual Reality as a Clinical Tool for Pain Management.
    Curr Pain Headache Rep 2018 Jun 15;22(8):53. Epub 2018 Jun 15.
    Department of Emergency Medicine, George Washington University School of Medicine and Health Sciences, 2120 L St., Washington, DC, 20037, USA.
    Purpose Of Review: To evaluate the use of virtual reality (VR) therapies as a clinical tool for the management of acute and chronic pain.

    Recent Findings: Recent articles support the hypothesis that VR therapies can effectively distract patients who suffer from chronic pain and from acute pain stimulated in trials. Clinical studies yield promising results in the application of VR therapies to a variety of acute and chronic pain conditions, including fibromyalgia, phantom limb pain, and regional specific pain from past injuries and illnesses. Read More

    Carpal tunnel syndrome after an electrical injury: a case report and review of literature.
    J Occup Health 2018 Jun 14. Epub 2018 Jun 14.
    Department of Environmental and Occupational Health, National Cheng Kung University.
    Introduction: Carpal tunnel syndrome (CTS) is prevalent in workers who utilize hand-held vibration tools, engage in tasks involving repetitive wrist movements, and suffer from wrist overuse. Although electrical injuries involving the median nerve are a relatively rare but plausible cause of CTS, the related literature is limited. Here, we report a case of CTS in which the symptoms developed after an electrical injury, and review the related literature. Read More

    Brief Electrical Stimulation Promotes Nerve Regeneration Following Experimental In-Continuity Nerve Injury.
    Neurosurgery 2018 Jun 11. Epub 2018 Jun 11.
    Department of Clinical Neuroscience, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Alberta, Canada.
    Background: Brief electrical stimulation (ES) therapy to the nerve may improve outcome in lacerated, repaired nerves. However, most human nerve injuries leave the nerve in continuity with variable and often poor functional recovery from incomplete axon regeneration and reinnervation.

    Objective: To evaluate the effect of brief ES in an experimental model for neuroma-in-continuity (NIC) injuries in rodents. Read More

    Changes in burn mortality in Bangladesh: Findings from Bangladesh Health and Injury Survey (BHIS) 2003 and 2016.
    Burns 2018 Jun 7. Epub 2018 Jun 7.
    Centre for Injury Prevention and Research Bangladesh, Dhaka, Bangladesh; Department of Epidemiology, Bangladesh University of Health Sciences, Bangladesh. Electronic address:
    Purpose: This paper is focused to reflect the changes in burn mortality and events leading to fatal burn injuries.

    Methods: Two national community-based cross sectional health and injury surveys were done in Bangladesh during 2003 and 2016. Similar methodology had been followed in both the surveys. Read More

    Eye injury from electrical weapon probes: Mechanisms and treatment.
    Am J Emerg Med 2018 Jun 2. Epub 2018 Jun 2.
    School of Criminal Justice, Texas State University, San Marcos, TX, United States.
    Purpose: While generally reducing morbidity and mortality, TASER® electrical weapons have risks associated with their usage, including burn injuries and head and cervical trauma associated with uncontrolled falls. The primary non-fatal complications appear to be significant eye injury but no analysis of the mechanisms or suggested treatments has been published.

    Methods: We used a biomechanical model to predict the risk of eye injury as a function of distance from the weapon muzzle to the eye. Read More

    Characteristics of burn injuries among children aged under six years in South Korea: Data from the Emergency Department-Based Injury In-Depth Surveillance, 2011-2016.
    PLoS One 2018 8;13(6):e0198195. Epub 2018 Jun 8.
    Department of Emergency Medicine, Inje University Ilsan Paik Hospital, Goyang, Korea.
    Studies show that young children are vulnerable to burn injuries. We aimed to investigate the characteristics of thermal injuries in this population. We included children below 6 years of age who visited the emergency department (ED) after thermal injuries who were registered in the Korean Emergency Department-based Injury In-Depth Surveillance (2011-2016) database. Read More

    Electrical Burns and Their Treatment in a Tertiary Hospital in Albania.
    Open Access Maced J Med Sci 2018 May 18;6(5):835-838. Epub 2018 May 18.
    Service of Burns and Plastic Surgery, UHC Mother Tereza, Rruga e Dibres Nr 370, Tirana, Albania.
    Introduction: The electrical current burns represent a very aggressive pathology that leaves many functional and aesthetic consequences.

    Aim: To evaluate the epidemiology of electrical burn injury and its associated complications and treatment.

    Material And Methods: Demographic data, aetiology, burn percentage and other measures related to electrical burn injury of 33 electrical burn patients in a tertiary hospital during the years 2015-2017. Read More

    A comparison of lower limb muscle activation pattern using voluntary response index between pronated and normal foot structures during forward jump landing.
    J Bodyw Mov Ther 2018 Apr 21;22(2):379-384. Epub 2017 Jul 21.
    Department of Physical Therapy, Faculty of Rehabilitation Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
    Background: Pronated of the foot is one of the important factors contributing to musculoskeletal problems affecting the lower extremities. It is known that in a pronated foot, excessive mechanical load is applied to the lower limb structures which may result in altered biomechanics and muscle activation patterns. The aim of this study was to determine changes in the muscle activation pattern of the lower extremities in individuals with pronated, compared to normal, feet, using the voluntary response index (VRI). Read More

    Electrical injury - a dual center analysis of patient characteristics, therapeutic specifics and outcome predictors.
    Scand J Trauma Resusc Emerg Med 2018 May 31;26(1):43. Epub 2018 May 31.
    Department of Plastic and Hand Surgery, Burn Center, Bergmannstrost Hospital, Merseburger Str. 165, 06112, Halle, Germany.
    Background: Electrical injuries represent life-threatening emergencies. Evidence on differences between high (HVI) and low voltage injuries (LVI) regarding characteristics at presentation, rhabdomyolysis markers, surgical and intensive burn care and outcomes is scarce.

    Methods: Consecutive patients admitted to two burn centers for electrical injuries over an 18-year period (1998-2015) were evaluated. Read More

    Injury Source and Correlation Analysis of Riders in Car-Electric Bicycle Accidents.
    Appl Bionics Biomech 2018 8;2018:3674858. Epub 2018 Apr 8.
    School of Automobile and Mechanical Engineering, Changsha University of Science and Technology, Changsha 410076, China.
    The knowledge about the injury source and correlation of riders in car-electric bicycle accident will be helpful in the cross validation of traces and vehicle safety design. In order to know more information about such kind of knowledge, 57 true car-electric bicycle accidents were reconstructed by PC-Crash and then data on injury information of riders were collected directly from the reconstructed cases. These collected data were validated by some existing research results firstly, and then 4 abnormal cases were deleted according to the statistical method. Read More

    Paediatric electrical burn injuries: experience from a tertiary care burns unit in North India.
    Ann Burns Fire Disasters 2017 Sep;30(3):185-188
    Department of Burns and Plastic Surgery, Sawai Man Singh Medical College and Hospital, Jaipur, India.
    Electrical burn injuries in the paediatric age group constitute a small proportion of all burn cases and cause significant morbidity and long-term psychosocial impact. The objective of this study was to evaluate various aspects of electrical burn injuries in the paediatric age group in our region. A retrospective review was done of all paediatric electrical burns admitted to a tertiary care burns unit over a period of 12 months (January 2016 to December 2016). Read More

    Lightning Burns and Electrical Trauma in a Couple Simultaneously Struck by Lightning.
    Clin Pract Cases Emerg Med 2017 Aug 17;1(3):246-250. Epub 2017 Jul 17.
    Memorial Regional Hospital, Division of Acute Care Surgery and Trauma, Hollywood, Florida.
    More people are struck and killed by lightning each year in Florida than any other state in the United States. This report discusses a couple that was simultaneously struck by lightning while walking arm-in-arm. Both patients presented with characteristic lightning burns and were admitted for hemodynamic monitoring, serum labs, and observation and were subsequently discharged home. Read More

    Effectiveness of low-frequency electrical stimulation in proprioceptive neuromuscular facilitation techniques in in healthy males: a randomized controlled trial.
    J Sports Med Phys Fitness 2018 May 29. Epub 2018 May 29.
    Physical Therapy Department, Universitat Internacional de Catalunya, Sant Cugat del Valles, Barcelona, Spain.
    Background: Hamstring muscle injuries are common in the sports field, with lack of hamstring flexibility being a risk factor. Stretching the hamstring muscles is an important part of the training and rehabilitation programs used to prevent or treat injury and improve performance. We aim to compare the immediate and follow-up effect on hamstring muscle flexibility between 2 different stretching protocols, proprioceptive neuromuscular facilitation (PNF) stretching and PNF stretching combined with electrostimulation. Read More

    Early rehabilitation for volumetric muscle loss injury augments endogenous regenerative aspects of muscle strength and oxidative capacity.
    BMC Musculoskelet Disord 2018 May 29;19(1):173. Epub 2018 May 29.
    Department of Kinesiology, University of Georgia, Athens, GA, 30602, USA.
    Background: Volumetric muscle loss (VML) injuries occur due to orthopaedic trauma or the surgical removal of skeletal muscle and result in debilitating long-term functional deficits. Current treatment strategies do not promote significant restoration of function; additionally appropriate evidenced-based practice physical therapy paradigms have yet to be established. The objective of this study was to develop and evaluate early rehabilitation paradigms of passive range of motion and electrical stimulation in isolation or combination to understand the genetic and functional response in the tissue remaining after a multi-muscle VML injury. Read More

    Necessity of early-stage verticalization in patients with brain and spinal cord injuries: Preliminary study.
    Technol Health Care 2018 May 18. Epub 2018 May 18.
    Department of Rehabilitation, Vilnius University, Faculty of Medicine, Physical and Sports Medicine, Vilnius, Lithuania.
    Background: Integration of the verticalization robot, Erigo, with functional electric stimulation and passive leg movements in the postacute rehabilitation of neurological patients could reduce the risk of secondary complications and improve functional outcomes (i.e. orthostatic hypotension, postural control and walking ability). Read More

    [Transferring the ulnaris proper digital nerve of index finger and its dorsal branch to repair the thumb nerve avulsion].
    Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2017 Aug;31(8):992-995
    Department of Hand Surgery, Renqiu City People's Hospital, Renqiu Hebei, 062550, P.R.China.
    Objective: To investigate the effectiveness of transferring the ulnaris proper digital nerve of index finger and its dorsal branch to repair the thumb nerve avulsion.

    Methods: Between January 2007 and May 2015, 23 patients with thumb nerve avulsion were treated by transferring the ulnaris proper digital nerve of index finger and its dorsal branch. There were 17 males and 6 females with an average age of 32 years (range, 16-63 years). Read More

    [New exploration on clinical treatment of injuries caused by uncommon agents or in extraordinary regions].
    Zhonghua Shao Shang Za Zhi 2018 May;34(5):263-265
    Center of Burns and Plastic Surgery of PLA, Lanzhou General Hospital, Lanzhou 730050, China.
    Burns caused by uncommon agents means those caused by other agents except heating power, with special characteristics existing in traumatogenesis, pathophysiology, and clinical manifestation. With the development of social economy, various new techniques and new equipments are springing up. In the practical use, improper operations would become traumatogenic agents and cause various special types of trauma. Read More

    A laboratory captured "giving way" episode in an individual with chronic ankle instability.
    J Biomech 2018 May 18. Epub 2018 May 18.
    School of Public Health, Physiotherapy and Sports Science, University College Dublin, Ireland; Institute for Sport & Health, University College Dublin, Ireland.
    This brief report details the first ever instrument-based motion description of an accidental "giving way" episode of the ankle joint incurred by a recreational male athlete (age = 22 years; height = 1.78 m; body mass = 97 kg) with chronic ankle instability whilst he was performing a change of direction task. Five inertial measurement units, as well as a high-speed video camera captured his lower limb kinematics during the performance of a maximum effort Agility T-Test, including his accidental "giving way" episode. Read More

    High-voltage electrical injury complicated by compartment syndrome and acute kidney injury with successful limb salvage: A case report and review of the literature.
    Int J Surg Case Rep 2018 May 16;48:38-42. Epub 2018 May 16.
    Department of Plastic, Reconstructive and Aesthetic Surgery, Singapore General Hospital, Outram Road Singapore, 169608, Singapore. Electronic address:
    Introduction: Although an uncommon form of admission to a burns centre, the deep, penetrating nature of noxious currents mean that electrical burns have the most catastrophic consequences of all burn injuries. Understanding the physics of electricity is crucial to explaining the mechanisms of tissue damage and organ failure in electrical injuries which necessitate special management above and beyond that of regular thermal burns.

    Presentation Of Case: We present a young man who suffered significant occupation-related electrical burns that was complicated by compartment syndrome, rhabdomyolysis and acute kidney injury. Read More

    Numerical Investigation on Head and Brain Injuries Caused by Windshield Impact on Riders Using Electric Self-Balancing Scooters.
    Appl Bionics Biomech 2018 25;2018:5738090. Epub 2018 Mar 25.
    Advanced Vehicle Research Center (AVRC), Beihang University, Beijing 100191, China.
    To investigate head-brain injuries caused by windshield impact on riders using electric self-balancing scooters (ESS). Numerical vehicle ESS crash scenarios are constructed by combining the finite element (FE) vehicle model and multibody scooter/rider models. Impact kinematic postures of the head-windshield contact under various impact conditions are captured. Read More

    Reconstruction of Extensive Post-Electric Burn Scalp Defects With Exposed Bones: A Study of 12 Cases.
    Ann Plast Surg 2018 Jul;81(1):39-44
    From the Institute for Research and Rehabilitation of Hand, and Department of Plastic Surgery, Government Stanley Medical College, Chennai, Tamil Nadu, India.
    The scalp is a unique part of the human body with respect to its shape and position. It is the part of the body that is usually exposed in its original form, with no covering by any means of clothing. In workplaces, especially in the electrical industry in the area of electrical substations and power transmission lines it is this part of the body that can easily come in contact with high tension electrical wires. Read More

    Axonal chronic injury in treatment-naïve HIV+ adults with asymptomatic neurocognitive impairment and its relationship with clinical variables and cognitive status.
    BMC Neurol 2018 May 10;18(1):66. Epub 2018 May 10.
    Department of Radiology, Beijing YouAn Hospital, Capital Medical University, No.8, Xi Tou Tiao, Youanmen Wai, Feng Tai District, Beijing, 100069, China.
    Background: HIV is a neurotropic virus, and it can bring about neurodegeneration and may even result in cognitive impairments. The precise mechanism of HIV-associated white matter (WM) injury is unknown. The effects of multiple clinical contributors on WM impairments and the relationship between the WM alterations and cognitive performance merit further investigation. Read More

    Risk factors of fatal occupational accidents in Iran.
    Ann Occup Environ Med 2018 2;30:29. Epub 2018 May 2.
    7Bachelor of Occupational Health Engineering, Environmental & Occupational Health Center, Ministry of Health and Medical Education, Tehran, Iran.
    Background: Occupational accidents are of most important consequences of globalization in developing countries. Therefore, investigating the causes of occupational accidents for improving the job situation and making operational policy is necessary. So the aim of this study was to investigate factors affecting the fatal occupational accidents and also calculate the years of life lost for dead workers. Read More

    PrismPlus: a mouse line expressing distinct fluorophores in four different brain cell types.
    Sci Rep 2018 May 8;8(1):7182. Epub 2018 May 8.
    Department of Neuroscience, University of Florida, Gainesville, FL, USA.
    To screen the complex central nervous system (CNS) injury responses, we created a quadruple-labelled 'PrismPlus' mouse line with a genetically encoded distinct fluorescent tag in oligodendrocytes, microglia, neurons, and astrocytes. Cx3cr1-gfp and Prism mice originally developed by Jung et al., 2000 and Dougherty et al. Read More

    Towards Optimal Platform-Based Robot Design for Ankle Rehabilitation: The State of the Art and Future Prospects.
    J Healthc Eng 2018 15;2018:1534247. Epub 2018 Mar 15.
    School of Mechanical and Electrical Engineering, Wuhan University of Technology, Wuhan, China.
    This review aims to compare existing robot-assisted ankle rehabilitation techniques in terms of robot design. Included studies mainly consist of selected papers in two published reviews involving a variety of robot-assisted ankle rehabilitation techniques. A free search was also made in Google Scholar and Scopus by using keywords "ankle," and "robot," and ("rehabilitat" or "treat"). Read More

    Cervical Myelopathy after High-voltage Electrical Burn of the Head: Report of an Unusual Case.
    Ann Indian Acad Neurol 2018 Jan-Mar;21(1):76-79
    Department of Neurology, North Eastern Indira Gandhi Regional Institute of Medical Sciences, Shillong, Meghalaya, India.
    High-voltage electrical injuries are uncommonly reported and may predispose to both immediate and delayed neurologic complications. We present a case of 27-year-old male who experienced a high-voltage electrical burn of the head resulting in quadriparesis. High-voltage electrocution injuries are a serious problem with potential for immediate, delayed, and long-term neurologic sequelae. Read More

    Balance Control and Energetics of Powered Exoskeleton-Assisted Sit-to-Stand Movement in Individuals with Paraplegic Spinal Cord Injury.
    Arch Phys Med Rehabil 2018 Apr 27. Epub 2018 Apr 27.
    Institute of Electrical Control Engineering, National Chiao Tung University, Hsinchu, Taiwan.
    Objective: To quantify the effects of initial hip angle and angular hip velocity settings of a lower-limb wearable robotic exoskeleton (WRE) on the balance control and mechanical energy requirements in patients with paraplegic spinal cord injuries (SCI) during WRE-assisted sit-to-stand (STS).

    Design: Observational, cross-sectional study.

    Setting: A university hospital gait laboratory with an 8-camera motion analysis system, three forceplates, a pair of instrumented crutches, and a WRE. Read More

    Myocardial tissue characterization by combining late gadolinium enhancement imaging and percent edema mapping: a novel T2 map-based MRI method in canine myocardial infarction.
    Eur Radiol Exp 2018 16;2(1). Epub 2018 Mar 16.
    1Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Dr, Charleston, SC 29425 USA.
    Background: Assessing the extent of ischemic and reperfusion-associated myocardial injuries remains challenging with current magnetic resonance imaging (MRI) techniques. Our aim was to develop a tissue characterization mapping (TCM) technique by combining late gadolinium enhancement (LGE) with our novel percent edema mapping (PEM) approach to enable the classification of tissue represented by MRI voxels as healthy, myocardial edema (ME), necrosis, myocardial hemorrhage (MH), or scar.

    Methods: Six dogs underwent closed-chest myocardial infarct (MI) generation. Read More

    A Rare Case of Triceps Brachii Injury after Electrocution.
    J Hand Microsurg 2018 Apr 29;10(1):46-48. Epub 2017 Nov 29.
    Department of Orthopaedics and Traumatology, University of Modena and Reggio Emilia, Modena, Italy.
    Injuries of the triceps brachii muscle are a rare entity and mostly concern its distal tendon. These represent the least common of all muscle and tendons injuries. The most common reported causes are repeated strong physical efforts, a fall on an outstretched forearm when a sudden deceleration is put on contract triceps, or a direct trauma. Read More

    Sport-Specific Assessment of the Effectiveness of Neuromuscular Training in Young Athletes.
    Front Physiol 2018 11;9:264. Epub 2018 Apr 11.
    Department of Sports Kinanthropology, Faculty of Physical Education and Sport, Comenius University in Bratislava, Bratislava, Slovakia.
    Neuromuscular training in young athletes improves performance and decreases the risk of injuries during sports activities. These effects are primarily ascribed to the enhancement of muscle strength and power but also balance, speed and agility. However, most studies have failed to demonstrate significant improvement in these abilities. Read More

    A comparative study of unintentional injuries among schooling left-behind, migrant and residential children in China.
    Int J Equity Health 2018 Apr 23;17(1):47. Epub 2018 Apr 23.
    School of Humanities and Social Sciences, North China Electric Power University, No.689, Huadian Road, Lianchi District, Baoding, Hebei, 071003, People's Republic of China.
    Background: Children who suffer from parental migration have been manifested to exhibit physical and mental impairments at higher rates. This current study aims to explore unintentional injury disparity among schooling left-behind children, migrant children and residential children in China, and to examine the risk factors of unintentional injury among the three types of children based on a multi-level system framework. This study will fill the gaps of this topic for China and contribute to the world literature in the context of countries with frequent population migration. Read More

    A Wearable Body Controlling Device for Application of Functional Electrical Stimulation.
    Sensors (Basel) 2018 Apr 18;18(4). Epub 2018 Apr 18.
    Department of Veterinary Medicine & Biological Science, Texas A&M University, College Station, TX 77843, USA.
    In this research, we describe a new balancing device used to stabilize the rear quarters of a patient dog with spinal cord injuries. Our approach uses inertial measurement sensing and direct leg actuation to lay a foundation for eventual muscle control by means of direct functional electrical stimulation (FES). During this phase of development, we designed and built a mechanical test-bed to develop the control and stimulation algorithms before we use the device on our animal subjects. Read More

    Protective Effect of Moderate Exogenous Electric Field Stimulation on Activating Netrin-1/DCC Expression Against Mechanical Stretch-Induced Injury in Spinal Cord Neurons.
    Neurotox Res 2018 Apr 7. Epub 2018 Apr 7.
    Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100083, China.
    Nerve cells detect and respond to electric field stimulation and extrinsic chemical guidance cues during development and regeneration; therefore, the development and optimization of an approach for functional neuronal regeneration are necessary for a nerve injury. In this study, we proposed using electric field stimulation to repair a nerve injury triggered by serious mechanical stretch loading. A device that provides continuous mechanical stretch and constant electric field stimulation was designed. Read More

    Stretchable Transparent Electrode Arrays for Simultaneous Electrical and Optical Interrogation of Neural Circuits in Vivo.
    Nano Lett 2018 May 9;18(5):2903-2911. Epub 2018 Apr 9.
    School of Life Sciences , Tsinghua University , Beijing 100084 , China.
    Recent developments of transparent electrode arrays provide a unique capability for simultaneous optical and electrical interrogation of neural circuits in the brain. However, none of these electrode arrays possess the stretchability highly desired for interfacing with mechanically active neural systems, such as the brain under injury, the spinal cord, and the peripheral nervous system (PNS). Here, we report a stretchable transparent electrode array from carbon nanotube (CNT) web-like thin films that retains excellent electrochemical performance and broad-band optical transparency under stretching and is highly durable under cyclic stretching deformation. Read More

    Erythropoietin Protects Retina Against Ceramide 2-Induced Damage in Rat.
    Curr Mol Med 2017 ;17(10):699-706
    Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Tongji University School of Medicine, Shanghai, China.
    Background: Ceramide plays critical roles in cell proliferation, senescence and apoptosis, and is implicated in neurodegenerative diseases, etc. To clarify if ceramide plays some roles in retinal diseases, we established in vivo and in vitro retinal injury models with ceramide 2 (C2) treatment. In addition, Erythropoietin (EPO), which showed protective effects on retinal cells and blood-retinal barrier (BRB), was also tested for its protection and possible mechanism(s) in these models. Read More

    The effect of pelvic floor muscle training and intravaginal electrical stimulation on urinary incontinence in women with incomplete spinal cord injury: an investigator-blinded parallel randomized clinical trial.
    Int Urogynecol J 2018 Mar 24. Epub 2018 Mar 24.
    Department of Obstetrics and Gynecology, Herlev and Gentofte Hospital, University of Copenhagen, Herlev, Denmark.
    Introduction And Hypothesis: Urinary incontinence is a prevalent problem in women with spinal cord injury. The aim of this study was to examine the effect of pelvic floor muscle training (PFMT) alone and combined with intravaginal electrical stimulation (IVES) on urinary incontinence in women with incomplete spinal cord injury.

    Methods: In this investigator-blinded randomized clinical trial, we recruited women aged 18-75 with incomplete spinal cord injury and urinary incontinence from a single spinal cord injury clinic in Denmark. Read More

    Motor Cortex Stimulation Regenerative Effects in Peripheral Nerve Injury: An Experimental Rat Model.
    World Neurosurg 2018 Jun 20;114:e800-e808. Epub 2018 Mar 20.
    Laboratory of Research in Neurosciences (Mechanisms and Application of Neuromodulation), Faculty of Medicine, St. Joseph University, Beirut, Lebanon; Department of Neurosurgery, Hôtel-Dieu de France Hospital, Beirut, Lebanon. Electronic address:
    Background: Immediate microsurgical nerve suture remains the gold standard after peripheral nerve injuries. However, functional recovery is delayed, and it is satisfactory in only 2/3 of cases. Peripheral electrical nerve stimulation proximal to the lesion enhances nerve regeneration and muscle reinnervation. Read More

    Label-free photoacoustic microscopy for in-vivo tendon imaging using a fiber-based pulse laser.
    Sci Rep 2018 Mar 19;8(1):4805. Epub 2018 Mar 19.
    Advanced Photonics Research Institute, Gwangju Institute of Science and Technology, 123 Cheomdan-gwagiro, Buk-gu, Gwangju, 61005, South Korea.
    Tendons are tough, flexible, and ubiquitous tissues that connect muscle to bone. Tendon injuries are a common musculoskeletal injury, which affect 7% of all patients and are involved in up to 50% of sports-related injuries in the United States. Various imaging modalities are used to evaluate tendons, and both magnetic resonance imaging and sonography are used clinically to evaluate tendons with non-invasive and non-ionizing radiation. Read More

    Impact of Regular Physical Activity on Adipocytokines and Cardiovascular Characteristics in Spinal Cord-Injured Subjects.
    Arch Phys Med Rehabil 2018 Mar 13. Epub 2018 Mar 13.
    Department of Internal Medicine, University of Campinas, Campinas, SP, Brazil. Electronic address:
    Objective: To investigate the relationship of carotid artery intima-media thickness (IMT) and cardiac structure and function with adipocytokines in sedentary (S-SCI) and physically active (PA-SCI) subjects with spinal cord injury (SCI).

    Design: Cross-sectional observational study.

    Setting: Academic medical center. Read More

    [Effects of decompression combined with electro-acupuncture on rat with acute severe upper cervical spinal cord compression injury].
    Zhongguo Gu Shang 2018 Jan;31(1):67-73
    China-Japan Friendship Hospital, Beijing 100029, China;
    Objective: To explore the effect and underlying mechanism of decompression(DE)combined with Governor Vessel(GV)electro-acupuncture(EA) on rats with acute severe upper cervical spinal cord compression injury.

    Methods: Thirty SPF rats were randomly divided into 5 groups(control group A, B and experiment group C, D, E), 6 rats in each group. The model of acute severe upper cervical spinal cord compression injury were made by forcing a balloon catheter put in atlas pillow clearance. Read More

    Automatic application of neural stimulation during wheelchair propulsion after SCI enhances recovery of upright sitting from destabilizing events.
    J Neuroeng Rehabil 2018 Mar 12;15(1):17. Epub 2018 Mar 12.
    Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA.
    Background: The leading cause of injury for manual wheelchair users are tips and falls caused by unexpected destabilizing events encountered during everyday activities. The purpose of this study was to determine the feasibility of automatically restoring seated stability to manual wheelchair users with spinal cord injury (SCI) via a threshold-based system to activate the hip and trunk muscles with electrical stimulation during potentially destabilizing events.

    Methods: We detected and classified potentially destabilizing sudden stops and turns with a wheelchair-mounted wireless inertial measurement unit (IMU), and then applied neural stimulation to activate the appropriate muscles to resist trunk movement and restore seated stability. Read More

    Ultrastructural brain abnormalities and associated behavioral changes in mice after low-intensity blast exposure.
    Behav Brain Res 2018 Jul 8;347:148-157. Epub 2018 Mar 8.
    Department of Pathology & Anatomical Sciences, University of Missouri School of Medicine, Columbia, MO 65212, USA; Truman VA Hospital Research Service, Columbia, MO 65201, USA. Electronic address:
    Explosive blast-induced mild traumatic brain injury (mTBI), a "signature wound" of recent military conflicts, commonly affects service members. While past blast injury studies have provided insights into TBI with moderate- to high-intensity explosions, the impact of primary low-intensity blast (LIB)-mediated pathobiology on neurological deficits requires further investigation. Our prior considerations of blast physics predicted ultrastructural injuries at nanoscale levels. Read More

    An epidemiological study on home injuries among children of 0-14 years in South Delhi.
    Indian J Public Health 2018 Jan-Mar;62(1):4-9
    Director Professor and Head, Department of Community Medicine, Lady Hardinge Medical College, New Delhi, India.
    Background: Injuries are an important public health problem worldwide, accounting for 5 million deaths, of which unintentional injuries account for 0.8 million deaths in children. Though there are many factors responsible for injury in the home, the environment plays an important role. Read More

    Use of motor evoked potentials during lateral lumbar interbody fusion reduces postoperative deficits.
    Spine J 2018 Apr 3. Epub 2018 Apr 3.
    Capital Region Special Surgery PLLC, 1220 New Scotland Rd, Slingerlands, NY 12159, USA.
    Background Context: Intraoperative neurophysiological monitoring (IONM) has gained rather widespread acceptance as a method to mitigate risk to the lumbar plexus during lateral lumbar interbody fusion (LLIF) surgery. The most common approach to IONM involves using only electromyography (EMG) monitoring, and the rate of postoperative deficit remains unacceptably high. Other test modalities, such as transcranial electric motor-evoked potentials (tcMEPs) and somatosensory-evoked potentials, may be more suitable for monitoring neural integrity, but they have not been widely adopted during LLIF. Read More

    A Randomized, Controlled Clinical Study to Assess the Effect of Anodal and Cathodal Electrical Stimulation on Periwound Skin Blood Flow and Pressure Ulcer Size Reduction in Persons with Neurological Injuries.
    Ostomy Wound Manage 2018 Feb;64(2):10-29
    Department of Medical Biophysics, Medical University of Silesia, Katowice.
    The use of electrical stimulation (ES) should be considered for treating nonhealing pressure ulcers (PUs), but optimal ES wound treatment protocols have yet to be established. A randomized, controlled, double-blind clinical study was conducted to evaluate the effects of cathodal and anodal high-voltage monophasic pulsed current (HVMPC) on periwound skin blood flow (PSBF) and size reduction of Stage 2 to Stage 4 PUs of at least 4 weeks' duration. Persons >18 years of age, hospitalized with neurological injuries, at high risk for PU development (Norton scale <14 points; Waterlow scale >15 points), and with at least 1 Stage 2 to Stage 4 PU were eligible to participate in the study. Read More

    Could the correct side of mediolateral episiotomy be determined according to anal sphincter EMG?
    Int Urogynecol J 2018 Feb 26. Epub 2018 Feb 26.
    Rīga Stradiņš University, Riga, Latvia.
    Introduction And Hypothesis: Mediolateral episiotomy is one of the most frequent surgical interventions performed in obstetrics. There is conflicting evidence as to whether mediolateral episiotomy reduces the risk of obstetric anal sphincter injuries (OASI). Recent studies suggest that functional asymmetry of pelvic floor innervation exists in healthy women and is strongly associated with postpartum incontinence when the trauma occurs on the dominant side of innervation. Read More

    Measurement of Microvascular Endothelial Barrier Dysfunction and Hyperpermeability In Vitro.
    Methods Mol Biol 2018 ;1717:237-242
    Department of Surgery, Texas A&M University Health Science Center, College of Medicine, Baylor Scott and White Research Institute, Temple, TX, USA.
    Loss of microvascular endothelial barrier integrity leads to vascular hyperpermeability and vasogenic edema in a variety of disease processes including trauma, ischemia and sepsis. Understanding these principles gives valuable information on pathophysiology and therapeutic drug development. While animal models of traumatic and ischemic injuries are useful to understand vascular dysfunctions associated with such injuries, in vitro barrier integrity assays are reliable and helpful adjuncts to understand the cellular and molecular changes and signaling mechanisms that regulate barrier function. Read More

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