Eur Rev Med Pharmacol Sci 2017 May;21(9):2061-2068

Department of Radiological Sciences, Catholic University of the "Sacred Heart", Polyclinic Gemelli Foundation, School of Medicine, Rome, Italy.

Objective: We aim to present clinical features, imaging findings, treatment aspects of the elastofibroma dorsi (ED), which is a benign tumor arising from connective tissue at the scapular region, and long-term outcomes after surgical resection.

Patients And Methods: We evaluated retrospectively 82 patients (55 females, 27 males; mean age, 60 years; age range, 23-78 years) with ED who underwent surgery between January 1994 and May 2014; subsequently all patients were invited for follow-up, which consisted of physical and US examinations.

Results: Subscapular location was almost constant (79/82 patients). Read More

Rev Esp Med Nucl Imagen Mol 2017 May 15. Epub 2017 May 15.

Servicio de Medicina Nuclear, Hospital Universitario Son Espases, Spain; Instituto de Investigación Sanitaria de Palma, Spain.

Radioiodine uptake in the thyroid tissue, metastasis of differentiated thyroid cancer (DTC), and in other tissues, depends on the expression of sodium-iodide symporter (NIS). Vascular permeability, effusions, inflammation, and other mechanisms may also play a role in the accumulation of radioactive iodine. A 63-year-old woman underwent radioiodine therapy, as well as a post-therapy whole-body scan,as she was suspected of having lung metastasis from thyroid carcinoma. Read More

Ear Nose Throat J 2017 Apr-May;96(4-5):160

Department of Pathology, Southern California Permanente Medical Group, Woodland Hills Medical Center, Woodland Hills, CA, USA.

SICOT J 2017 5;3:34. Epub 2017 May 5.

Department of Radiology, University of California San Diego, 200 West Arbor Drive, Mail Code: 8756, San Diego, CA 92130, USA.

Lipomatous lesions are common musculoskeletal lesions that can arise within the soft tissues, bone, neurovascular structures, and synovium. The majority of these lesions are benign, and many of the benign lesions can be diagnosed by radiologic evaluation. However, radiologic differences between benign and malignant lipomatous lesions may be subtle and pathologic correlation is often needed. Read More

Acta Reumatol Port 2017 Jan-Mar;42(1):91-93

Hospital de Braga.

Objectives: Elastofibroma dorsi is an uncommon benign tumor, typically located in the subscapularis region. Our goal is to describe the main features of elastofibroma dorsi to increase awareness of its existence and proper management.

Material And Methods: We report a case of a 59-year-old woman with bilateral Elastofibroma dorsi and made a brief review of the epidemiological, clinical and radiodiagnostic features of this entity. Read More

Skeletal Radiol 2017 Mar 5;46(3):393-397. Epub 2017 Jan 5.

III Orthopaedic and Traumatology Clinic, Rizzoli Orthopaedic Institute, Via Pupilli 1, 40136, Bologna, Italy.

A 51-year-old man presented with elastofibroma (EF) of the gluteal region with a concomitant contralateral lesion. The patient presented with a slow growing mass of the proximal third of the right buttock and had swelling, discomfort in sitting, and right-hip pain during walking for 2 months. On MRI, a soft-tissue mass was noted between the gluteus maximus and the gluteus medius muscle. Read More

Case Rep Gastrointest Med 2016 6;2016:2697187. Epub 2016 Nov 6.

University of Nebraska Medical Center, Omaha, NE, USA.

Elastofibroma is a benign tumor of the musculoskeletal system characterized by the abnormal accumulation of elastinophilic fibers. It has been classically described for subscapular region but has been reported in several musculoskeletal sites over the years and rarely even in the GI tract but never in pancreas. We therefore present the case of a 45-year-old female who presented with intermittent abdominal pain. Read More

Acta Orthop Traumatol Turc 2017 Jan 22;51(1):7-11. Epub 2016 Oct 22.

Çukurova University Faculty of Medicine, Department of Orthopedics and Traumatology, Adana, Turkey.

Objective: Elastofibroma dorsi (ED) is a rare, benign, soft tissue tumor typically located between inferior corner of scapula and posterior chest wall causing mass, scapular snapping, and pain. When classic symptoms and localization are present, it is diagnosed without biopsy and treated with marginal resection. This study retrospectively analyzed patients operated on for ED to evaluate presenting symptoms, tumor size, complications, and clinical results, and to suggest optimal treatments. Read More

ANZ J Surg 2016 Nov 31;86(11):946-947. Epub 2014 Jul 31.

Upper Gastro-Intestinal and Hepato-Biliary Unit, The Canberra Hospital, Canberra, Australian Capital Territory, Australia.

J Stroke Cerebrovasc Dis 2016 Oct 15;25(10):e185-7. Epub 2016 Aug 15.

Department of Neurology and Psychiatry, Endovascular Neurosurgery/Interventional Neuroradiology, Sapienza University of Rome, Rome, Italy.

A 75-year-old man with hypertension and atrial fibrillation was admitted to our emergency room with right-sided hemiplegia and complete aphasia (National Institutes of Health Stroke Scale [NIHSS] score = 18). A noncontrast computed tomography scan showed a slight hypodensity in the left insular region and a bright hyperdense sign in the M1 tract of the left middle cerebral artery (MCA). Angio-CT confirmed an occlusion of the M1 tract of the MCA. Read More

Asian Cardiovasc Thorac Ann 2016 Oct 4;24(8):831-832. Epub 2016 Jul 4.

Department of Thoracic Surgery, Ankara Numune Research and Training Hospital, Ankara, Turkey.

Nucl Med Commun 2016 Aug;37(8):837-42

Departments of aNuclear Medicine bDiagnostic Imaging cRadiation Oncology, Chaim Sheba Medical Center, Tel Hashomer dSackler School of Medicine, Tel Aviv University, Ramat Aviv eDivision of Surgery, Assaf Harofeh Medical Center, Zerifin, Israel fInstitute of Nuclear Medicine, University College London and UCL Hospitals, London, UK.

Objective: We describe changes in elastofibroma dorsi (EFD) as observed in serial fluorine-18 fluorodeoxyglucose (F-FDG) PET-computed tomography (CT) imaging studies.

Materials And Methods: F-FDG PET-CT studies carried out between January 2006 and January 2015 at a single institution were reviewed by an experienced radiologist and nuclear medicine specialist. When available, previous or subsequent imaging studies were reviewed to evaluate changes in EFD. Read More

J Cutan Aesthet Surg 2016 Jan-Mar;9(1):34-7

Department of General Surgery, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.

Elastofibromas are rare benign, soft-tissue slow-growing tumors seen predominantly in elderly females. The most common location is the infrascapular region. These benign tumors require resection only in symptomatic cases. Read More

Radiol Bras 2016 Jan-Feb;49(1):61

Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil.

Ann R Coll Surg Engl 2016 Mar;98(3):208-11

The Sarcoma Unit , The Royal Marsden Hospital NHS Foundation Trust , UK.

Introduction: Elastofibromas are rare, pseudo-tumours arising at the inferior pole of the scapula that have a characteristic presentation. Due to their tissue of origin and size, they may often be mistaken for soft tissue sarcomas. We present the management of patients diagnosed with elastofibroma at a single institution. Read More

Medicine (Baltimore) 2016 Feb;95(7):e2832

From the Department of Imaging and Medical Information Sciences, Radiology (SPM, JG); and Department of Imaging and Medical Information Sciences, Nuclear Medicine (CTV), Geneva University Hospital, Geneva, Switzerland.

A 70-year-old male patient underwent an Fluorodeoxyglucose-positron emission tomography-computed tomography for staging of a left parahilar lung neoplasm found during work-up for fatigue and asthenia. The scan demonstrated a hypermetabolic lung tumor, a hypermetabolic pleural effusion and 4 hypermetabolic bilateral soft tissue lesions of the chest wall corresponding to 4 elastofibroma dorsi. Initially, the oncologic disease was classified as stage IV because of the hypermetabolic pleural effusion. Read More

Kardiochir Torakochirurgia Pol 2015 Dec 30;12(4):355-8. Epub 2015 Dec 30.

Klinikum Doebeln, Germany.

Elastofibroma dorsi is a rare benign tumor of the back, located between the latissimus dorsi and the rhomboid muscle. In most cases it is unilateral, but in up to 10% it occurs on both sides. The etiology is still in discussion. Read More

J Orthop 2015 Oct 24;12(Suppl 1):S133-6. Epub 2014 Jul 24.

Department of Oncologic Surgery, Salah Azaïz Institute, Tunis 1006, Tunisia.

Introduction: Elastofibroma is a rare benign fibroelastic tumor.

Case: We report a case of a 44-year-old woman, operated 4 months ago for a left infrascapular desmoid tumor and presented for bilateral mass of the left suprascapular and right infrascapular regions which were surgically resected. The diagnosis of elastofibroma was made and also confirmed for the left infrascapular desmoid tumor. Read More

Future Oncol 2015 ;11(24 Suppl):47-50

Section of Thoracic Surgery, Department of General Surgery & Medical Specialities, University of Catania, Policlinico University Hospital, Catania, Italy.

A total of 13 patients (11 females, average age of 63 years) with elastofibromadorsi were retrospectively analyzed. The disease was confirmed by surgical intervention in five cases. In other patients (n = 8) the diagnosis was achieved on the basis of clinical and radiological features. Read More

Ann Dermatol Venereol 2016 Jan 25;143(1):27-31. Epub 2015 Nov 25.

Service de dermatologie, CHRU de Tours, 37044 Tours cedex 09, France; Faculté de médecine de Tours, 10, boulevard Tonnellé, 37032 Tours, France.

Introduction: Ischaemic fasciitis (IF) is a rare pseudosarcomatous proliferation initially described on the pressure points of long-term bedridden patients. Healing is the rule after surgical excision. No multifocal localisations have been reported to date. Read More

Med Mol Morphol 2016 Jun 9;49(2):83-8. Epub 2015 Nov 9.

Department of Dermatology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka, 545-8585, Japan.

Elastofibroma is a rare tumour that occurs in the subscapular space, and it typically presents in middle-aged and older individuals. The aetiology of elastofibroma remains unknown. Recent, sporadic reports have shown, immunohistologically, that fibroblasts in elastofibroma may produce abnormal elastic and collagen fibres through the action of transforming growth factor-beta (TGF-β), a factor that promotes fibroblast proliferation. Read More

Endoscopy 2015 14;47 Suppl 1 UCTN:E471-2. Epub 2015 Oct 14.

Endoscopy Service, Department of Diagnostic and Therapeutic Services, IRCCS - ISMETT (Istituto Mediterraneo per i Trapianti e Terapie ad alta specializzazione), Palermo, Italy.

Clin Imaging 2016 Jan-Feb;40(1):110-3. Epub 2015 Aug 15.

Department of PET/CT, The Second Affiliated Hospital of Qingdao University Medical College (Municipal Central Hospital of Qingdao), No127. SiLiu Nan Street, QingDao City, ShanDong Province, 266042, P.R. China.

Purpose: To assess the characteristics of 18F-FDG uptake in elastofibroma dorsi (EFD).

Methods: Seventeen patients with EFD were retrospectively studied.

Results: The mean±S. Read More

Int J Surg Pathol 2016 Apr 29;24(2):126-7. Epub 2015 Sep 29.

Department of Diagnostic Pathology, NTT Medical Center Tokyo, Tokyo, Japan.

Pan Afr Med J 2015 21;21:43. Epub 2015 May 21.

Service de Chirurgie Plastique, Reconstructrice, Esthetique et Brules, CHU Mohamed VI, Marrakech, Maroc.

Pan Afr Med J 2015 8;20:337. Epub 2015 Apr 8.

Service de Chirurgie Pédiatrique, CHU Hassan II, Fès, Maroc.

Ann Thorac Surg 2015 Jul;100(1):302-4

Department of Pathology, Gazi University School of Medicine, Ankara, Turkey.

Elastofibroma is a benign and slow-growing soft tissue tumor that classically presents as an ill-defined solitary mass at the inferior pole of the scapula in the fifth and sixth decades of life for women. This tumor can be rarely seen in childhood, but it has not been reported in the infantile age group to date. To our knowledge, this case represents the first report of elastofibroma in the infantile age group. Read More

J Dent (Shiraz) 2015 Mar;16(1 Suppl):73-5

Dept. of Oral and Maxillofacial Pathology, School of Dentistry, Kerman University of Medical Sciences, Kerman, Iran, Oral and Dental Disease Research Center, Kerman University of Medical Sciences, Kerman, Iran;

Elastofibroma is a rare neoplasm that characteristically occurs in subscapular area in response to microtrauma. There are some reports of this tumor in other sites of the body but, up till now, there has been no report of elastofibroma in the face. A 20-year-old man presented with a slow growing painless mass in the face without any history of trauma. Read More

Med Mol Morphol 2016 Mar 4;49(1):42-7. Epub 2015 Jun 4.

Department of Plastic and Reconstructive Surgery, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka, 573-1010, Japan.

Elastofibroma is a rare, benign, fibrous tumor formed by the proliferation of characteristic elastic fibers that commonly occurs between the lower margin of the scapula and the ribcage. We undertook a histochemical, immunohistochemical, and ultrastructural study of an elastofibroma dorsi beneath the right scapula of a 77-year-old woman. Tumor cells comprised collagen fiber bundles, numerous elastic fibers, and spindle cells resembling fibroblasts. Read More

Eur J Histochem 2015 Feb 19;59(1):2459. Epub 2015 Feb 19.

Magna Græcia University of Catanzaro.

Elastofibroma dorsi (ED) is considered a member of a heterogeneous group of benign fibrous (fibroblastic or myofibroblastic) soft-tissue tumors, frequently localized in the periscapular region in middle aged or older individuals. However, the pathogenesis of ED is still unclear and many authors believe that ED results from a reactive hyperproliferation of fibroblastic tissue, while others suggest that it may be a consequence of a mechanical friction. In our study, we examined 11 cases of ED using histochemical and immunohistochemical methods, in order to extend the knowledge about extracellular matrix composition and histopathogenesis of ED. Read More

Clin Neuropathol 2015 May-Jun;34(3):169-71

Int Orthop 2015 Jun 21;39(6):1145-9. Epub 2015 Mar 21.

Orthopaedics and Traumatology Department, University Hospital Reina Sofía, Córdoba, Spain,

Purpose: Elastofibroma dorsi (ED) is a rare soft-tissue tumour. Diagnosis is made using imaging, mainly magnetic resonance due to its higher sensitivity and specificity in soft tissues. No agreement exists when deciding which imaging test must be used. Read More

J Thorac Oncol 2015 Apr;10(4):e18-20

Departments of *Surgery-Thoracic Surgery, †Opthalmology, ‡Pathology, §Upstate Heart and Vascular Center, and ‖Radiology, State University of New York, Upstate Medical University, Syracuse, New York; and ¶Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, New York.

Ann Ital Chir 2014 Dec 29;85(ePub). Epub 2014 Dec 29.

Elastofibroma is a rare benign lesion that typically arises on the posterior chest wall beneath the scapula. The etiopathogenesis is still unclear and the knowledge about its diagnosis and management mainly comes from small case series. We collected all the data related to 11 Elastofibroma Dorsi treated at our institution between January 2003 and July 2014. Read More

Ann Ital Chir 2014 Mar 20;85(ePub). Epub 2014 Mar 20.

Elastofibroma is a benign slow-growing neoplasm of soft tissues, originally defined Elastofibroma dorsi because of the typical localization in the connective tissue placed between the bottom corner of the scapula and the chest wall. From 1990 to 2013 at our center, 115 patients underwent elestofibroma surgical removal, including 2 bilateral and one relapsed. For all the patients ultrasound preoperative examination was requested, sometimes with a diagnosis of lipoma or fibrolipoma because of the rarity of this type of lesion and therefore the lack of experience of the radiologists. Read More

Eur J Dermatol 2014 Nov-Dec;24(6):691-3

Department of Dermatology, Faculty of Medicine, Oita University, Hasama, Yufu, 879-5593, Japan.

Ann Nucl Med 2015 Jun 11;29(5):420-5. Epub 2015 Feb 11.

Department of Nuclear Medicine, Faculty of Medicine, Baskent University, Ankara, Turkey,

Objective: Elastofibroma dorsi (ED) is a rare pseudotumor of the soft tissues that can also show 18F-fluorodeoxyglucose ((18)F-FDG) uptake on positron emission tomography combined with computed tomography (PET/CT) imaging. The aim of this retrospectively study was to describe the metabolic characteristics of ED incidentally detected by (18)F-FDG PET/CT imaging.

Materials And Methods: Between November 2009 and August 2013 at our institution, 10,350 consecutive PET/CT examinations were retrospectively investigated. Read More

Case Rep Pathol 2015 6;2015:967670. Epub 2015 Jan 6.

Department of Radiology, Antalya Training and Research Hospital, 07058 Antalya, Turkey.

We present a case of a 54-year-old female patient. MRI examination showed a mass adjacent to the left scapula and a localized heterogeneous mass in the right subscapular area. Microscopic examination revealed abnormal elastic fibers and globules and mature adipose tissue mixed with collagen bands in all areas of the lesion. Read More

Clin Ter 2014;165(6):e413-5

Department of Surgical Sciences, "Sapienza" University of Rome, Italy.

Elastofibroma Dorsi (EFD) is a rare pseudo-tumor characterized by the overgrowth of elastic fibers mixed to adipose and connective tissues typically growing in the subscapular region. This can be bilateral but only rarely synchronous affecting different anatomical sites at the same time. Hereby we present a case of a 42-year-old male patient found with three different metachronous elastofibromas: bilateral EFD and a further third localization by the right elbow. Read More

Tunis Med 2014 May;92(5):354-5

Int J Surg Case Rep 2014 4;5(12):1139-41. Epub 2014 Nov 4.

Istanbul Medical Faculty, Department of General Surgery, Istanbul University, Istanbul, Turkey.

Introduction: Elastofibroma dorsi(EFD) is slow-growing, benign, soft tissue tumor of unclear pathogenesis, typically located at the subscapular region of elderly people. It may be unilateral or bilateral. As it exhibits benign behavior, it should be surgically removed only in symptomatic patients. Read More

Ann Transl Med 2013 Oct;1(3):31

1 Department of Pathology, Abderrahmen Mami Hospital, Ariana, Tunisia ; 2 Department of Thoracic Surgery, Abderrahmen Mami Hospital, Ariana, Tunisia.

Elastofibromas are benign soft tissue tumors. They occur mostly in the infrascapular region between the thoracic wall, the serratus anterior and the latissimus dorsi muscle, with a prevalence of up to 24% in the elderly. The etiology of this lesion remains uncertain and is a source of ongoing debate. Read More

West Indian Med J 2014 Mar 11;63(2):189-91. Epub 2014 Apr 11.

Department of Otorhinolaryngology, Head and Neck Surgery, West China Hospital, Sichuan University, Sichuan, China.

We report the case of a 45-year-old woman with a painless soft tissue mass on the left side of her neck. At surgery, the lesion was solid and rubbery and revealed gray-white fibrous areas. It was pathologically confirmed as an elastofibroma. Read More

Ugeskr Laeger 2014 Sep;176(40)

Ortopædkirurgisk Afdeling, Sydvestjysk Sygehus, Finsensgade 35, 6700 Esbjerg. E-mail:

Elastofibroma dorsi (ED) is a benign, slow-growing soft tissue pseudo-tumor and is regarded as rare. The aetiology is unclear and ED is often associated with only distinct symptoms. This case report describes a 55-year-old woman with bilateral ED, who underwent surgical treatment with great result. Read More

Pol J Pathol 2014 Jun;65(2):120-4

Funda Tasli MD Department of Pathology Faculty of Medicine Sifa University 35100, Bornova Izmir, Turkey tel. +902323434445-1450 fax: +902322502997 e-mail:

Elastofibromas are slow-growing and rare soft-tissue tumors. The etiology and pathogenetic mechanisms are still controversial and there are only a few studies in the literature investigating the histochemical, immunohistochemical, and genetic features to determine the pathogenesis. We investigated the cellular composition of lesions with a diagnosis of elastofibroma in 17 patients by using histochemical and immunohistochemical methods. Read More

Ann Thorac Surg 2014 Aug;98(2):e31-2

Department of Genetics, Faculty of Medicine, EGE University, Izmir, Turkey.

Elastofibroma dorsi is a rare, slowly growing, benign soft tissue tumor located in the periscapular region on the chest wall. Although it is generally unilateral, it may be bilateral in 10% of cases. The tumor is located between the costa and the chest wall muscles. Read More

Eklem Hastalik Cerrahisi 2014 ;25(2):117-20

Department of Orthopedics and Traumatology, Başkent University Alanya Research and Application Center, 07400 Alanya, Antalya, Turkey.

Elastofibroma dorsi is a rare soft tissue pseudotumor which is located at the anteroinferior aspect of the scapula. In this article, we report a 19-year-old female case who had arthroscopic marginal excision of elastofibroma dorsi at the scapulothoracic joint without recurrences during follow-up. The arthroscopic marginal excision of the elastofibroma dorsi may have good clinical results in selected cases. Read More

Orthop Rev (Pavia) 2014 Apr 16;6(2):5329. Epub 2014 Jun 16.

Department of Orthopedics, University Clinic Dusseldorf , Germany.

Elastofibroma (EF) is a benign proliferation of connective tissue and is typically located at the dorsal thoracic wall. Most patients complain about pain during motion in the shoulder girdle. The aim of our study was to evaluate the outcome after surgical treatment of EF. Read More

Pediatr Neurosurg 2013 27;49(4):240-2. Epub 2014 Jun 27.

Virgen del Rocío Hospital, Seville, Spain.

Elastofibroma is a benign fibroproliferative tumor of unknown origin and pathogenesis. It usually appears in the subscapular or infrascapular area. It is extremely rare in the spinal area, and it is most common in middle-aged women. Read More

Int J Clin Exp Pathol 2014 15;7(5):2291-7. Epub 2014 Apr 15.

Department of Clinical Laboratory Medicine and Division of Diagnostic Pathology, Shiga University of Medical Science Shiga, Japan.

Elastofibromatous change, also referred to as elastofibromatous polyp or elastofibroma, has been extremely rarely described in the gastrointestinal tract. This lesion is characterized histopathologically by an excessive accumulation of elastic fibers occasionally with a fibrous component involving the submucosa and/or muscularis mucosae of the gastrointestinal tract. Herein, we report four additional lesions of the intestine and review the clinicopathological features of this rare lesion. Read More