Search Our Scientific Publications & Authors

J Clin Anesth 2019 Feb 8;56:108. Epub 2019 Feb 8.

Maltepe University Faculty of Medicine, Department of Medical Education, Istanbul, Turkey.

Am J Dermatopathol 2019 Feb;41(2):85-117

Department of Dermatology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain.

After a review of the physiology in the formation and degradation of cutaneous elastic tissue, we describe the clinicopathologic disorders characterized by increased and decreased cutaneous elastic tissue. Cutaneous disorders characterized by increased and/or abnormal elastic tissue in the dermis include elastoma, also named nevus elasticus, dermatosis lenticularis disseminata, pseudoxanthoma elasticum, late-onset focal dermal elastosis, linear focal elastosis, elastoderma, elastofibroma dorsi, and elastosis perforans serpiginosa. In some of these conditions, the specific histopathologic diagnosis may be rendered with hematoxylin-eosin stain, whereas in other ones special elastic tissue stains are necessary to demonstrate the anomalies. Read More

Rev Esp Patol 2019 Jan - Mar;52(1):3-10. Epub 2018 May 22.

Departamento de Anatomía Patológica, Facultad de Medicina, Pontificia Universidad Católica de Chile , Santiago, Chile. Electronic address:

Introduction: Gastrointestinal elastofibromatous polyps are rare benign lesions. In 1985, Enjoji described elastofibromatous change of the stomach but since only isolated cases have been reported, with none in Spanish language journals. They present as single, usually asymptomatic, polypoid lesions, most frequently in the large intestine. Read More

Am J Gastroenterol 2019 Jan;114(1):12

Walter Reed National Military Medical Center, Gastroenterology, Bethesda, MD, USA.

Tunis Med 2018 Jan;96(1):64-67

Elastofibromas are rare benign soft tissue tumors that are commonly located at the inferior pole of the scapula, typically in the right side, deep to the serratus anterior muscle. They occur mainly in elderly women and are usually asymptomatic. We  present four cases of elastofibroma dorsi in which the clinical and ultrasound diagnosis was confirmed by CT and magnetic resonance imaging. Read More

J Dermatol 2018 Sep 28. Epub 2018 Sep 28.

Department of Dermato-Oncology/Dermatology, National Hospital Organization Kagoshima Medical Center, Kagoshima, Japan.

Kyobu Geka 2018 09;71(9):716-719

Department of Surgery, Jikei University Katsushika Medical Center, Tokyo, Japan.

Elastofibroma is a relatively rare tumor that occurs commonly at the apex of scapula in elderly people. We report a case of elastofibroma of a female in her seventies. She visited our hospital with complaints of painful mass in her back, which was increasing in size. Read More

J Clin Anesth 2019 02 29;52:34-35. Epub 2018 Aug 29.

Maltepe University Faculty of Medicine, Department of Anesthesiology and Reanimation, Turkey.

J Natl Med Assoc 2018 Oct 2;110(5):428-430. Epub 2017 Nov 2.

Department of Radiology, Ufuk University School of Medicine, Ankara, Turkey.

Elastofibroma dorsi is a reactive pseudotumor of connective tissue, typically located in the infrascapular region. Awareness of this benign entity is crucial for radiologists, as well as clinicians, to avoid misdiagnosis and potential patient harm. In this report, we present clinical and imaging findings of an elastofibroma dorsi after a thoracotomy procedure. Read More

G Ital Dermatol Venereol 2018 Jun;153(3):446-447

Department of Dermatology and Venerology, Central Teaching Hospital of Bolzano, Bolzano, Italy.

Clin Nucl Med 2018 May;43(5):e154-e155

From the Department of Radiology, University of Washington, Seattle, WA.

Sixty six-year-old woman status post ileocecal resection for well-differentiated neuroendocrine tumor in the terminal ileum 7 years ago, who is on octreotide therapy for liver metastases. Ga DOTATATE PET/CT showed soft tissue masses with mildly increased radiotracer uptake in the bilateral subscapular/infrascapular regions. In retrospective image review, these soft tissue masses were first noted 7 years prior and have gradually increased in size over the years. Read More

J Ultrason 2017 Dec 29;17(71):281-288. Epub 2017 Dec 29.

Self-education Sonography Group, Genetics Division, Pomeranian Medical University, Szczecin, Poland.

Chest wall neoplasms mainly include malignancies, metastatic in particular. Differential diagnosis should include clinical data; tumor location, extent, delineation; the degree of homogeneity; the presence of calcifications; the nature of bone destruction and the degree of vascularization. The aim of the paper is to present both the benefits and limitations of ultrasound for the diagnosis of chest wall neoplasms. Read More

Surg Case Rep 2017 Dec 6;3(1):121. Epub 2017 Dec 6.

Department of General Thoracic Surgery, Takamatsu Municipal Hospital, 2-36-1 Miyawakichou, Takamatsu, Kagawa, 760-8538, Japan.

In recent years, the number of cancer patients who undergo endoscopic surgery has been increasing, and port-site recurrence is becoming a more common complication. A 66-year-old woman underwent thoracoscopic left lower lobectomy with lymph node dissection for pT1aN0M0 adenocarcinoma of the lung. Six years after surgery, CT revealed a subscapular tumor measuring 3 cm at the site of the surgical port wound. Read More

Skeletal Radiol 2018 04 23;47(4):569-573. Epub 2017 Nov 23.

Department of Radiology, Vall d'Hebron University Hospital, Barcelona, Spain.

We report a case of triple elastofibromas located in the supra- and infrascapular regions. A 61-year-old female with a history of bilateral elastofibroma in the typical subscapular region (6 years before) was admitted for the evaluation of a left-sided suprascapular mass that she had first noted 3 months before. On physical examination, a firm, painless, mobile mass was palpated in the subcutaneous tissue. Read More

Pan Afr Med J 2017 14;28:34. Epub 2017 Sep 14.

Surgical Oncology Department 1, National Institute of Oncology, University Mohamed V Rabat, Morocco.

Elastofibroma dorsi (ED) is an uncommon benign soft tissue tumor with an uncertain pathogenesis. It mostly occurs in the infrascapular region of elderly people with a female predominance. Typically bilateral, ED can also be unilateral. Read More

Acta Radiol 2018 Jun 18;59(6):709-715. Epub 2017 Sep 18.

1 Department of Radiology, Graduate School of Medical Science, University of the Ryukyus, Okinawa, Japan.

Background Elastofibroma dorsi is a rare pseudotumoral lesion. Thus, there is no report of magnetic resonance imaging (MRI) findings that investigates multiple patients particularly with respect to diffusion-weighted imaging (DWI) findings and contrast enhancement patterns. Purpose To describe the imaging findings of elastofibroma on MRI, particularly DWI findings and contrast enhancement patterns, and to further investigate patient demographics. Read More

Int J Surg Pathol 2018 Apr 1;26(2):161-164. Epub 2017 Sep 1.

1 University of Rochester Medical Center, Rochester, NY, USA.

We report 2 unusual elastotic lesions of intestinal subserosal fat. The first arose in the small bowel subserosa of a 64-year-old woman with volvulus. It was undetected macroscopically and consisted of a relatively circumscribed focus of elastosis, with essentially no evidence of fibrosis or blood vessel walls within. Read More

Arch Bronconeumol 2018 Feb 27;54(2):102. Epub 2017 Jul 27.

Servicio de Cirugía Torácica, Hospital Universitario Ramón y Cajal, Madrid, España.

Nucl Med Commun 2017 Sep;38(9):795-798

aDepartment of Urology, The James Buchanan Brady Urological Institute bThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Objective: PET imaging using radiotracers that target prostate-specific membrane antigen (PSMA) are increasingly being used in the evaluation of men with prostate cancer (PCa). It is therefore of increasing importance for imaging specialists to recognize potential pitfalls of this novel imaging technique. In this report, we describe a series of benign elastofibroma dorsi with uptake of the PSMA-targeted PET radiotracer F-DCFPyL. Read More

Proc (Bayl Univ Med Cent) 2017 Jul;30(3):340-342

Department of Radiology, St. Vincent's Medical Center, Bridgeport, Connecticut (Goyal, Gandhi, S. Gupta, Olsavsky, N. Gupta); and the Department of Radiology, Yale New Haven Health at Bridgeport Hospital, Bridgeport, Connecticut (Li, Kumar, Olsavsky).

We present a 60-year-old man with biopsy-proven metastatic squamous cell carcinoma of the right inguinal and external iliac lymph nodes with unknown primary. Hypermetabolic soft tissue masses were identified in bilateral subscapular regions on follow-up positron emission tomography (PET)-computed tomography (CT) after completion of chemoradiation. The right subscapular mass was biopsied under CT guidance, and histopathology showed it to be elastofibroma dorsi. Read More

Eur Rev Med Pharmacol Sci 2017 05;21(9):2061-2068

Department of Radiological Sciences, Catholic University of the "Sacred Heart", Polyclinic Gemelli Foundation, School of Medicine, Rome, Italy.

Objective: We aim to present clinical features, imaging findings, treatment aspects of the elastofibroma dorsi (ED), which is a benign tumor arising from connective tissue at the scapular region, and long-term outcomes after surgical resection.

Patients And Methods: We evaluated retrospectively 82 patients (55 females, 27 males; mean age, 60 years; age range, 23-78 years) with ED who underwent surgery between January 1994 and May 2014; subsequently all patients were invited for follow-up, which consisted of physical and US examinations.

Results: Subscapular location was almost constant (79/82 patients). Read More

Rev Esp Med Nucl Imagen Mol 2018 Jan - Feb;37(1):46-49. Epub 2017 May 16.

Servicio de Medicina Nuclear, Hospital Universitario Son Espases, Palma de Mallorca, Islas Baleares, España; Instituto de Investigación Sanitaria de Palma, Palma de Mallorca, Islas Baleares, España.

Radioiodine uptake in the thyroid tissue, metastasis of differentiated thyroid cancer (DTC), and in other tissues, depends on the expression of sodium-iodide symporter (NIS). Vascular permeability, effusions, inflammation, and other mechanisms may also play a role in the accumulation of radioactive iodine. A 63-year-old woman underwent radioiodine therapy, as well as a post-therapy whole-body scan, as she was suspected of having lung metastasis from thyroid carcinoma. Read More

Ear Nose Throat J 2017 Apr-May;96(4-5):160

Department of Pathology, Southern California Permanente Medical Group, Woodland Hills Medical Center, Woodland Hills, CA, USA.

SICOT J 2017 5;3:34. Epub 2017 May 5.

Department of Radiology, University of California San Diego, 200 West Arbor Drive, Mail Code: 8756, San Diego, CA 92130, USA.

Lipomatous lesions are common musculoskeletal lesions that can arise within the soft tissues, bone, neurovascular structures, and synovium. The majority of these lesions are benign, and many of the benign lesions can be diagnosed by radiologic evaluation. However, radiologic differences between benign and malignant lipomatous lesions may be subtle and pathologic correlation is often needed. Read More

Acta Reumatol Port 2017 Jan-Mar;42(1):91-93

Hospital de Braga.

Objectives: Elastofibroma dorsi is an uncommon benign tumor, typically located in the subscapularis region. Our goal is to describe the main features of elastofibroma dorsi to increase awareness of its existence and proper management.

Material And Methods: We report a case of a 59-year-old woman with bilateral Elastofibroma dorsi and made a brief review of the epidemiological, clinical and radiodiagnostic features of this entity. Read More

Skeletal Radiol 2017 Mar 5;46(3):393-397. Epub 2017 Jan 5.

III Orthopaedic and Traumatology Clinic, Rizzoli Orthopaedic Institute, Via Pupilli 1, 40136, Bologna, Italy.

A 51-year-old man presented with elastofibroma (EF) of the gluteal region with a concomitant contralateral lesion. The patient presented with a slow growing mass of the proximal third of the right buttock and had swelling, discomfort in sitting, and right-hip pain during walking for 2 months. On MRI, a soft-tissue mass was noted between the gluteus maximus and the gluteus medius muscle. Read More

Case Rep Gastrointest Med 2016 6;2016:2697187. Epub 2016 Nov 6.

University of Nebraska Medical Center, Omaha, NE, USA.

Elastofibroma is a benign tumor of the musculoskeletal system characterized by the abnormal accumulation of elastinophilic fibers. It has been classically described for subscapular region but has been reported in several musculoskeletal sites over the years and rarely even in the GI tract but never in pancreas. We therefore present the case of a 45-year-old female who presented with intermittent abdominal pain. Read More

Acta Orthop Traumatol Turc 2017 Jan 22;51(1):7-11. Epub 2016 Oct 22.

Çukurova University Faculty of Medicine, Department of Orthopedics and Traumatology, Adana, Turkey.

Objective: Elastofibroma dorsi (ED) is a rare, benign, soft tissue tumor typically located between inferior corner of scapula and posterior chest wall causing mass, scapular snapping, and pain. When classic symptoms and localization are present, it is diagnosed without biopsy and treated with marginal resection. This study retrospectively analyzed patients operated on for ED to evaluate presenting symptoms, tumor size, complications, and clinical results, and to suggest optimal treatments. Read More

ANZ J Surg 2016 Nov 31;86(11):946-947. Epub 2014 Jul 31.

Upper Gastro-Intestinal and Hepato-Biliary Unit, The Canberra Hospital, Canberra, Australian Capital Territory, Australia.

J Stroke Cerebrovasc Dis 2016 Oct 15;25(10):e185-7. Epub 2016 Aug 15.

Department of Neurology and Psychiatry, Endovascular Neurosurgery/Interventional Neuroradiology, Sapienza University of Rome, Rome, Italy.

A 75-year-old man with hypertension and atrial fibrillation was admitted to our emergency room with right-sided hemiplegia and complete aphasia (National Institutes of Health Stroke Scale [NIHSS] score = 18). A noncontrast computed tomography scan showed a slight hypodensity in the left insular region and a bright hyperdense sign in the M1 tract of the left middle cerebral artery (MCA). Angio-CT confirmed an occlusion of the M1 tract of the MCA. Read More

Asian Cardiovasc Thorac Ann 2016 Oct 4;24(8):831-832. Epub 2016 Jul 4.

Department of Thoracic Surgery, Ankara Numune Research and Training Hospital, Ankara, Turkey.

Nucl Med Commun 2016 Aug;37(8):837-42

Departments of aNuclear Medicine bDiagnostic Imaging cRadiation Oncology, Chaim Sheba Medical Center, Tel Hashomer dSackler School of Medicine, Tel Aviv University, Ramat Aviv eDivision of Surgery, Assaf Harofeh Medical Center, Zerifin, Israel fInstitute of Nuclear Medicine, University College London and UCL Hospitals, London, UK.

Objective: We describe changes in elastofibroma dorsi (EFD) as observed in serial fluorine-18 fluorodeoxyglucose (F-FDG) PET-computed tomography (CT) imaging studies.

Materials And Methods: F-FDG PET-CT studies carried out between January 2006 and January 2015 at a single institution were reviewed by an experienced radiologist and nuclear medicine specialist. When available, previous or subsequent imaging studies were reviewed to evaluate changes in EFD. Read More

J Cutan Aesthet Surg 2016 Jan-Mar;9(1):34-7

Department of General Surgery, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.

Elastofibromas are rare benign, soft-tissue slow-growing tumors seen predominantly in elderly females. The most common location is the infrascapular region. These benign tumors require resection only in symptomatic cases. Read More

Radiol Bras 2016 Jan-Feb;49(1):61

Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil.

Ann R Coll Surg Engl 2016 Mar;98(3):208-11

The Sarcoma Unit , The Royal Marsden Hospital NHS Foundation Trust , UK.

Introduction: Elastofibromas are rare, pseudo-tumours arising at the inferior pole of the scapula that have a characteristic presentation. Due to their tissue of origin and size, they may often be mistaken for soft tissue sarcomas. We present the management of patients diagnosed with elastofibroma at a single institution. Read More

Medicine (Baltimore) 2016 Feb;95(7):e2832

From the Department of Imaging and Medical Information Sciences, Radiology (SPM, JG); and Department of Imaging and Medical Information Sciences, Nuclear Medicine (CTV), Geneva University Hospital, Geneva, Switzerland.

A 70-year-old male patient underwent an Fluorodeoxyglucose-positron emission tomography-computed tomography for staging of a left parahilar lung neoplasm found during work-up for fatigue and asthenia. The scan demonstrated a hypermetabolic lung tumor, a hypermetabolic pleural effusion and 4 hypermetabolic bilateral soft tissue lesions of the chest wall corresponding to 4 elastofibroma dorsi. Initially, the oncologic disease was classified as stage IV because of the hypermetabolic pleural effusion. Read More

Kardiochir Torakochirurgia Pol 2015 Dec 30;12(4):355-8. Epub 2015 Dec 30.

Klinikum Doebeln, Germany.

Elastofibroma dorsi is a rare benign tumor of the back, located between the latissimus dorsi and the rhomboid muscle. In most cases it is unilateral, but in up to 10% it occurs on both sides. The etiology is still in discussion. Read More

J Orthop 2015 Oct 24;12(Suppl 1):S133-6. Epub 2014 Jul 24.

Department of Oncologic Surgery, Salah Azaïz Institute, Tunis 1006, Tunisia.

Introduction: Elastofibroma is a rare benign fibroelastic tumor.

Case: We report a case of a 44-year-old woman, operated 4 months ago for a left infrascapular desmoid tumor and presented for bilateral mass of the left suprascapular and right infrascapular regions which were surgically resected. The diagnosis of elastofibroma was made and also confirmed for the left infrascapular desmoid tumor. Read More

Future Oncol 2015 ;11(24 Suppl):47-50

Section of Thoracic Surgery, Department of General Surgery & Medical Specialities, University of Catania, Policlinico University Hospital, Catania, Italy.

A total of 13 patients (11 females, average age of 63 years) with elastofibromadorsi were retrospectively analyzed. The disease was confirmed by surgical intervention in five cases. In other patients (n = 8) the diagnosis was achieved on the basis of clinical and radiological features. Read More

Ann Dermatol Venereol 2016 Jan 25;143(1):27-31. Epub 2015 Nov 25.

Service de dermatologie, CHRU de Tours, 37044 Tours cedex 09, France; Faculté de médecine de Tours, 10, boulevard Tonnellé, 37032 Tours, France.

Introduction: Ischaemic fasciitis (IF) is a rare pseudosarcomatous proliferation initially described on the pressure points of long-term bedridden patients. Healing is the rule after surgical excision. No multifocal localisations have been reported to date. Read More

Med Mol Morphol 2016 Jun 9;49(2):83-8. Epub 2015 Nov 9.

Department of Dermatology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka, 545-8585, Japan.

Elastofibroma is a rare tumour that occurs in the subscapular space, and it typically presents in middle-aged and older individuals. The aetiology of elastofibroma remains unknown. Recent, sporadic reports have shown, immunohistologically, that fibroblasts in elastofibroma may produce abnormal elastic and collagen fibres through the action of transforming growth factor-beta (TGF-β), a factor that promotes fibroblast proliferation. Read More

Endoscopy 2015 14;47 Suppl 1 UCTN:E471-2. Epub 2015 Oct 14.

Endoscopy Service, Department of Diagnostic and Therapeutic Services, IRCCS - ISMETT (Istituto Mediterraneo per i Trapianti e Terapie ad alta specializzazione), Palermo, Italy.

Clin Imaging 2016 Jan-Feb;40(1):110-3. Epub 2015 Aug 15.

Department of PET/CT, The Second Affiliated Hospital of Qingdao University Medical College (Municipal Central Hospital of Qingdao), No127. SiLiu Nan Street, QingDao City, ShanDong Province, 266042, P.R. China.

Purpose: To assess the characteristics of 18F-FDG uptake in elastofibroma dorsi (EFD).

Methods: Seventeen patients with EFD were retrospectively studied.

Results: The mean±S. Read More

Int J Surg Pathol 2016 Apr 29;24(2):126-7. Epub 2015 Sep 29.

Department of Diagnostic Pathology, NTT Medical Center Tokyo, Tokyo, Japan.

Pan Afr Med J 2015 21;21:43. Epub 2015 May 21.

Service de Chirurgie Plastique, Reconstructrice, Esthetique et Brules, CHU Mohamed VI, Marrakech, Maroc.

Pan Afr Med J 2015 8;20:337. Epub 2015 Apr 8.

Service de Chirurgie Pédiatrique, CHU Hassan II, Fès, Maroc.

Ann Thorac Surg 2015 Jul;100(1):302-4

Department of Pathology, Gazi University School of Medicine, Ankara, Turkey.

Elastofibroma is a benign and slow-growing soft tissue tumor that classically presents as an ill-defined solitary mass at the inferior pole of the scapula in the fifth and sixth decades of life for women. This tumor can be rarely seen in childhood, but it has not been reported in the infantile age group to date. To our knowledge, this case represents the first report of elastofibroma in the infantile age group. Read More

J Dent (Shiraz) 2015 Mar;16(1 Suppl):73-5

Dept. of Oral and Maxillofacial Pathology, School of Dentistry, Kerman University of Medical Sciences, Kerman, Iran, Oral and Dental Disease Research Center, Kerman University of Medical Sciences, Kerman, Iran;

Elastofibroma is a rare neoplasm that characteristically occurs in subscapular area in response to microtrauma. There are some reports of this tumor in other sites of the body but, up till now, there has been no report of elastofibroma in the face. A 20-year-old man presented with a slow growing painless mass in the face without any history of trauma. Read More

Med Mol Morphol 2016 Mar 4;49(1):42-7. Epub 2015 Jun 4.

Department of Plastic and Reconstructive Surgery, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka, 573-1010, Japan.

Elastofibroma is a rare, benign, fibrous tumor formed by the proliferation of characteristic elastic fibers that commonly occurs between the lower margin of the scapula and the ribcage. We undertook a histochemical, immunohistochemical, and ultrastructural study of an elastofibroma dorsi beneath the right scapula of a 77-year-old woman. Tumor cells comprised collagen fiber bundles, numerous elastic fibers, and spindle cells resembling fibroblasts. Read More

Eur J Histochem 2015 Feb 19;59(1):2459. Epub 2015 Feb 19.

Magna Græcia University of Catanzaro.

Elastofibroma dorsi (ED) is considered a member of a heterogeneous group of benign fibrous (fibroblastic or myofibroblastic) soft-tissue tumors, frequently localized in the periscapular region in middle aged or older individuals. However, the pathogenesis of ED is still unclear and many authors believe that ED results from a reactive hyperproliferation of fibroblastic tissue, while others suggest that it may be a consequence of a mechanical friction. In our study, we examined 11 cases of ED using histochemical and immunohistochemical methods, in order to extend the knowledge about extracellular matrix composition and histopathogenesis of ED. Read More