ESC Heart Fail 2021 Apr 25;8(2):1637-1642. Epub 2021 Feb 25.
The Service of Adult Intensive Care Medicine, University Hospital and Faculty of Biology and Medicine, University of Lausanne, Rue du Bugnon 46, Lausanne, CH-1011, Switzerland.
Adult patients with uncorrected congenital heart diseases and chronic intracardiac shunt may develop Eisenmenger syndrome (ES) due to progressive increase of pulmonary vascular resistance, with significant morbidity and mortality. Acute decompensation of ES in conditions promoting a further increase of pulmonary vascular resistance, such as pulmonary embolism or pneumonia, can precipitate major arterial hypoxia and death. In such conditions, increasing systemic oxygenation with veno-venous extracorporeal membrane oxygenation (VV-ECMO) could be life-saving, serving as a bridge to treat a potential reversible cause for the decompensation, or to urgent lung transplantation. Read More