1,402 results match your criteria Eisenmenger Syndrome


Caudal vena cava aneurysm in a cat with Eisenmenger Syndrome.

J Vet Med Sci 2020 May 15. Epub 2020 May 15.

Department of Veterinary Medical Imaging, College of Veterinary Medicine, Konkuk University.

A seven-month-old cat was referred for evaluation of exercise intolerance and open-mouth breathing. Based on ultrasonographic examination, caudal vena cava (CVC) aneurysm associated with right congestive heart failure resulting from congenital heart disease was diagnosed. Conservative treatment for alleviating pulmonary hypertension mildly improved the clinical signs and decreased the heart size and CVC aneurysm diameter. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1292/jvms.19-0518DOI Listing

Pulmonary Hypertension in Adults with Congenital Heart Disease: Real-World Data from the International COMPERA-CHD Registry.

J Clin Med 2020 05 13;9(5). Epub 2020 May 13.

Universitätsklinik Köln- Herzzentrum, Klinik III für Innere Medizin, 50937 Köln, Germany.

Introduction: Pulmonary hypertension (PH) is a common complication in patients with congenital heart disease (CHD), aggravating the natural, post-operative, or post-interventional course of the underlying anomaly. The various CHDs differ substantially in characteristics, functionality, and clinical outcomes among each other and compared with other diseases with pulmonary hypertension.

Objective: To describe current management strategies and outcomes for adults with PH in relation to different types of CHD based on real-world data. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/jcm9051456DOI Listing

Cultivating Hope.

Authors:
Manpreet K Singh

JAMA 2020 May;323(18):1781-1782

Stanford University School of Medicine, Department of Psychiatry and Behavioral Sciences, Stanford, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jama.2020.4508DOI Listing

Eisenmenger Syndrome in Pregnancy: A Management Conundrum.

J Cardiothorac Vasc Anesth 2020 Mar 6. Epub 2020 Mar 6.

Department of Anesthesiology, University of Florida College of Medicine, Gainesville, FL.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.jvca.2020.02.053DOI Listing

[Risk factors for death and the clinical features of different subtypes of patients with pulmonary arterial hypertension related to congenital heart disease].

Zhonghua Xin Xue Guan Bing Za Zhi 2020 Apr;48(4):315-322

Department of Pediatric Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Disease, Beijing 100029, China.

To explore the risk factors for death in patients with pulmonary arterial hypertension related to congenital heart disease (PAH-CHD) and the clinical characteristics of different subtypes in patients with PAH-CHD. It was a retrospective study. A total of 507 PAH-CHD patients, who were hospitalized in the Department of Pediatric Cardiology of Beijing Anzhen Hospital between September 2005 and May 2019, were included. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.cn112148-20190628-00364DOI Listing

"Treat and repair" strategy for shunt lesions: a critical review.

Pulm Circ 2020 Apr-Jun;10(2):2045894020917885. Epub 2020 Apr 9.

Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India.

The issue of operability in patients with shunt lesions and raised pulmonary vascular resistance is contentious. Several reports suggest that patients traditionally considered inoperable may be operated after treatment with targeted drug therapy for pulmonary arterial hypertension. We reviewed all the published literature of "treat and repair" approach to gain more insights into the utility of this approach. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/2045894020917885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153197PMC

The COngenital HeARt Disease in adult and Pulmonary Hypertension (COHARD-PH) registry: a descriptive study from single-center hospital registry of adult congenital heart disease and pulmonary hypertension in Indonesia.

BMC Cardiovasc Disord 2020 Apr 7;20(1):163. Epub 2020 Apr 7.

Department of Cardiology and Vascular Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada - Dr. Sardjito Hospital, Yogyakarta, Indonesia.

Backgrounds: The COngenital HeARt Disease in adult and Pulmonary Hypertension (COHARD-PH) registry is the first registry for congenital heart disease (CHD) and CHD-related pulmonary hypertension (PH) in adults in Indonesia. The study aims to describe the demographics, clinical presentation, and hemodynamics data of adult CHD and CHD-related PH in Indonesia.

Methods: The COHARD-PH registry is a hospital-based, single-center, and prospective registry which includes adult patients with CHD and CHD-related PH. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12872-020-01434-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137468PMC

Atrial Septal Defect with Eisenmenger Syndrome: A Rare Presentation.

Case Rep Cardiol 2020 9;2020:8681761. Epub 2020 Mar 9.

Creighton University School of Medicine-Phoenix/Maricopa Integrated Health System, Department of Cardiology, 2601 E Roosevelt St., Phoenix, AZ 85008, USA.

Atrial septal defects (ASDs) are common congenital heart defects (CHD). The clinical course in patients without closure of the ASD is associated with significant morbidity and mortality in advanced age. A small percentage of patients may develop pulmonary arterial hypertension (PAH) due to left to right shunting that impacts morbidity and mortality. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2020/8681761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085360PMC

Diagnostic Challenges in Primary Sacral Tumors and the Yield of Computed Tomography-Guided Needle Biopsy in the Modern Era.

World Neurosurg 2020 Mar 25. Epub 2020 Mar 25.

Department of Neurological Surgery, University of California, San Francisco, California, USA. Electronic address:

Objective: Primary sacral tumors pose unique challenges because of their complex radiographic appearances, diverse pathologic entities, and dramatically different treatment paradigms based on tumor type. Magnetic resonance imaging and computed tomography (CT) can provide valuable information; however, sacral lesions can possess unique radiographic features and pose diagnostic dilemmas. CT-guided percutaneous needle biopsy is a critical component of the diagnostic workup. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2020.03.094DOI Listing

Recommendations for exercise in adolescents and adults with congenital heart disease.

Prog Cardiovasc Dis 2020 Mar 19. Epub 2020 Mar 19.

Department of Cardiology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia; Sydney Medical School, The University of Sydney, Camperdown, New South Wales, Australia. Electronic address:

The population of adults living with congenital heart disease (CHD) has grown rapidly in recent decades due to major advances in surgical and medical care. Although the benefits of physical activity (PA) and exercise are well recognised in the management of chronic diseases, the therapeutic role of exercise for the CHD population has been under-studied and under-recognised. In fact, people living with complex CHD have traditionally been advised against participation in moderate or vigorous PA due to safety concerns. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pcad.2020.03.002DOI Listing

Determinants of Sudden Cardiac Death in Adult Patients With Eisenmenger Syndrome.

J Am Heart Assoc 2020 Mar 15;9(6):e014554. Epub 2020 Mar 15.

Departments of Cardiovascular Diseases Mayo Clinic Jacksonville FL.

Background Patients with Eisenmenger syndrome are known to have a high incidence of sudden cardiac death (SCD), yet the underlying causes are not well understood. We sought to define the predictors of SCD in this population. Methods and Results A retrospective analysis of all patients with Eisenmenger syndrome from 2 large tertiary referral centers was performed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/JAHA.119.014554DOI Listing

Insights to correlations and discrepancies between impaired lung function and heart failure in Eisenmenger patients.

Pulm Circ 2020 Jan-Mar;10(1):1350650120909729. Epub 2020 Feb 28.

Clinic of Chest Diseases, Immunology and Allergology, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Impaired lung function and spirometric signs of airway obstruction without common risk factors for chronic obstructive pulmonary disease could be found in patients with Eisenmenger syndrome. This study aimed to analyse the association between lung function parameters and disease severity (including heart failure markers, associated congenital heart defect) as well as the possible reasons for airflow obstruction in Eisenmenger syndrome. The data of 25 patients with Eisenmenger syndrome were retrospectively evaluated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/2045894019899239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052468PMC
February 2020

A Doppler ghost in the pulmonary artery.

Echocardiography 2020 Mar 24;37(3):472-473. Epub 2020 Feb 24.

Department of Cardiology, Ankara City Hospital, Ankara, Turkey.

Long-standing left-to-right shunting across a patent ductus arteriosus (PDA) can result in Eisenmenger syndrome. In this report, we present echocardiographic findings of a 27-year-old female patient with pulmonary hypertension. In diagnostic work-up especially Doppler findings of the pulmonary artery suggested the presence of a reversed PDA as a cause of pulmonary hypertension. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/echo.14621DOI Listing

Pediatric heart-lung transplantation: A contemporary analysis of outcomes.

Pediatr Transplant 2020 May 17;24(3):e13682. Epub 2020 Feb 17.

Heart Institute, Cincinnati Children's Hospital, Cincinnati, Ohio.

Background: Pediatric heart-lung transplantation (HLT) is rare, and no report has analyzed patient outcomes since time of listing. We analyzed pediatric HLTs to understand risk factors for waitlist and post-HLT mortality.

Methods: All pediatric (<18 year old) HLT candidates were identified within the UNOS database (n = 573) and grouped by age, era, and by diagnosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/petr.13682DOI Listing

PDA with Eisenmenger Syndrome Masquerading as Idiopathic Pulmonary Hypertension.

J Assoc Physicians India 2020 Jan;68(1):53

JJM Medical College.

View Article

Download full-text PDF

Source
January 2020

Late infective endocarditis after transcatheter tricuspid valve-in-valve implantation: A pediatric case report.

Arch Pediatr 2020 Feb 16;27(2):107-109. Epub 2020 Jan 16.

Department of Pediatric and Congenital Cardiology, M3C Regional Reference Center, Montpellier University Hospital, PhyMedExp, Inserm, CNRS, University of Montpellier, 34295 Montpellier, France.

In patients with congenital heart diseases, new procedures, such as transcatheter valve replacement, have been associated with a non-negligible incidence of infective endocarditis (IE): up to 4% patient-year IE incidence. Prosthetic IE after percutaneous tricuspid valve replacement (PTVR) has been scarcely reported. We report the first pediatric case of IE after percutaneous tricuspid Melody™ valve-in-valve implantation in a boy who was diagnosed with Eisenmenger syndrome, related to patent ductus arteriosus. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.arcped.2019.12.002DOI Listing
February 2020

Emergency caesarean section of a patient with eisenmenger's syndrome: A tight-rope walk.

Ann Card Anaesth 2020 Jan-Mar;23(1):95-97

Department of Anaesthesiology, Seth G.S. Medical College and K.E.M. Hospital, Mumbai, Maharashtra, India.

Successful management of a pregnant patient with complex congenital heart disease is a challenge for anesthesiologists, requiring thorough knowledge of the impact of pregnancy on the cardiac lesion. Hearing and speech impaired patients pose a barrier to effective communication between the patient and the doctors, thus increasing the anxiety and risk of complications. Here, we present a case of a hearing and speech impaired woman with the rare and dangerous Eisenmenger's syndrome, presenting for an emergency cesarean section (CS). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/aca.ACA_175_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034216PMC
January 2020

Myocardial perfusion abnormalities in Eisenmenger syndrome.

Nucl Med Commun 2020 Mar;41(3):206-211

Departments of Cardiology.

Background: Compared to primary pulmonary hypertension (PPH), the right ventricular (RV) contractile function is preserved for a long time in patients with Eisenmenger syndrome and is likely the most important determinant of relatively higher survival. The differences in myocardial perfusion have been purported to explain this discrepancy. The exact prevalence of myocardial perfusion abnormalities in Eisenmenger syndrome is not known. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MNM.0000000000001147DOI Listing
March 2020
1.371 Impact Factor

Management of Persistent Pulmonary Hypertension After Correction of Congenital Heart Defect with Autologous Marrow-Derived Mononuclear Stem Cell Injection into the Pulmonary Artery: A Pilot Study.

Pediatr Cardiol 2020 Feb 7;41(2):398-406. Epub 2020 Jan 7.

Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Pulmonary arterial hypertension (PAH) related to left-to-right shunt can progress to Eisenmenger syndrome, a serious and fatal disease that is not yet curable. This pilot study considered stem cell injection as a new treatment modality in persistent pulmonary hypertension after the correction of a congenital heart defect. Three patients with persistent pulmonary hypertension after ventricular septal defect repair were included in this pilot study for a clinical trial. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00246-019-02273-2DOI Listing
February 2020

Left main coronary artery occlusion by external compression with a large pulmonary artery in Eisenmenger syndrome.

Anatol J Cardiol 2020 Jan;23(1):55-56

Department of Cardiology, Faculty of Medicine, Akdeniz University; Antalya-Turkey.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14744/AnatolJCardiol.2019.38845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141437PMC
January 2020

Pulmonary arterial hypertension populations of special interest: portopulmonary hypertension and pulmonary arterial hypertension associated with congenital heart disease.

Eur Heart J Suppl 2019 Dec 17;21(Suppl K):K37-K45. Epub 2019 Dec 17.

Cardiothoracic Department, S. Orsola University Hospital, 40138 Bologna, Italy.

Guidelines exist for management of pulmonary arterial hypertension (PAH), but information is limited for certain patient subgroups, including adults with portopulmonary hypertension (PoPH) or with PAH associated with congenital heart disease (PAH-CHD). This article discusses screening, clinical management, and prognosis in PoPH and PAH-CHD and, as such, considers the most recent clinical data and expert advice. A multidisciplinary consultation and follow-up by specialists are crucial for management of both PoPH and PAH-CHD, but each condition presents with unique challenges. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/eurheartj/suz221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915053PMC
December 2019

A hybrid approach to implantable cardioverter-defibrillator implantation in a patient with Eisenmenger syndrome.

Kardiol Pol 2020 02 10;78(2):167-168. Epub 2019 Dec 10.

Department of Cardiology, University Medical Center Ljubljana, Slovenia

View Article

Download full-text PDF

Source
http://dx.doi.org/10.33963/KP.15098DOI Listing
February 2020

Eisenmenger Syndrome: A Multisystem Disorder-Do Not Destabilize the Balanced but Fragile Physiology.

Can J Cardiol 2019 Dec 10;35(12):1664-1674. Epub 2019 Oct 10.

Toronto Congenital Cardiac Centre for Adults, Peter Munk Cardiac Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada. Electronic address:

Eisenmenger syndrome is the most severe and extreme phenotype of pulmonary arterial hypertension associated with congenital heart disease. A large nonrestrictive systemic left-to-right shunt triggers the development of pulmonary vascular disease, progressive pulmonary arterial hypertension, and increasing pulmonary vascular resistance at the systemic level, which ultimately results in shunt reversal. Herein, we review the changing epidemiological patterns and pathophysiology of Eisenmenger syndrome. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cjca.2019.10.002DOI Listing
December 2019

Severe pulmonary hypertension and reduced right ventricle systolic function associated with maternal mortality in pregnant uncorrected congenital heart diseases.

Pulm Circ 2019 Oct-Dec;9(4):2045894019884516. Epub 2019 Nov 18.

Department of Cardiology and Vascular Medicine, Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada and Dr Sardjito Hospital, Jogjakarta, Indonesia.

Background: Pregnant uncorrected congenital heart disease patients, especially those who already developed pulmonary hypertension, have increased risk for maternal mortality. The pulmonary hypertension severity and right ventricle function may be associated with higher maternal mortality. The study aimed to investigate the mortality rate of pregnant uncorrected congenital heart disease and the impact of pulmonary hypertension severity on mortality. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/2045894019884516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862778PMC
November 2019

Successful percutaneous coronary intervention with extracorporeal membrane oxygenation support after right coronary artery dissection in an eisenmenger syndrome patient.

Acute Crit Care 2020 Feb 6;35(1):46-50. Epub 2018 Nov 6.

Division of Cardiology, Department of Internal Medicine, Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea.

The presentation of coronary artery disease in a patient with Eisenmenger syndrome (ES) is relatively rare. Cardiogenic shock due to coronary artery dissection during percutaneous coronary intervention (PCI) can be more critical in these patients. Here, we report a case of successful PCI under mechanical circulation support in a patient with ES who experienced potentially fatal right coronary artery dissection. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4266/acc.2017.00024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056956PMC
February 2020
4 Reads

Arrhythmias in Adults With Congenital Heart Disease: What the Practicing Cardiologist Needs to Know.

Authors:
Paul Khairy

Can J Cardiol 2019 Dec 16;35(12):1698-1707. Epub 2019 Jul 16.

Electrophysiology Service and Adult Congenital Heart Disease Center, Montreal Heart Institute, Université de Montréal, Montreal, Québec, Canada. Electronic address:

The expanding population of adults with congenital heart disease (CHD) combined with the pervasiveness of arrhythmias has resulted in the rapid growth of a dedicated sector of cardiology at the intersection between 2 subspecialties: electrophysiology and adult CHD. Herein, practical considerations are offered regarding urgent referral for catheter ablation of atrial arrhythmias, anticoagulation, and primary prevention implantable cardioverter-defibrillators (ICDs). Patients with Ebstein anomaly and ventricular pre-excitation should be referred promptly due to the high prevalence of multiple accessory pathways and increased incidence of atrial tachyarrhythmias, which may be poorly tolerated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cjca.2019.07.009DOI Listing
December 2019

Heart-lung transplantation in Eisenmenger syndrome (two for the price of ?).

Heart 2020 Jan 24;106(2):94-96. Epub 2019 Oct 24.

Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/heartjnl-2019-315780DOI Listing
January 2020
1 Read

Heart-lung transplantation with concomitant aortic arch reconstruction for Eisenmenger syndrome and type B interrupted aortic arch.

J Heart Lung Transplant 2019 12 11;38(12):1320-1321. Epub 2019 Sep 11.

Department of Cardiothoracic Surgery, Stanford University, Stanford, California. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.healun.2019.09.002DOI Listing
December 2019
1 Read

Surgery for Eisenmenger syndrome: time for a rethink?

J R Soc Med 2019 12 17;112(12):512-513. Epub 2019 Sep 17.

Papworth Hospital NHS Foundation Trust, Cambridge CB2 0AY, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0141076819877551DOI Listing
December 2019
5 Reads

Pregnant Women With Uncorrected Congenital Heart Disease: Heart Failure and Mortality.

JACC Heart Fail 2020 Feb 11;8(2):100-110. Epub 2019 Sep 11.

Erasmus Medical Center, Rotterdam, the Netherlands. Electronic address:

Objectives: The purpose of this work was to study maternal and fetal outcomes of women with uncorrected congenital heart disease (CHD).

Background: Globally, CHD is an important cause of maternal morbidity and mortality in women reaching reproductive stage. Data are lacking from larger cohorts of women with uncorrected CHD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jchf.2019.09.001DOI Listing
February 2020
2 Reads

Endocarditis and bacterial brain abscess in a young woman with a single atrium, patent ductus arteriosus, and Eisenmenger syndrome: A case report.

Medicine (Baltimore) 2019 Sep;98(36):e17044

Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Rationale: A single atrium is a rare congenital heart disease (CHD) involving zero atrial septal traces and preserved intact ventricular septum and atrioventricular valves, requiring careful surgical intervention. However, developing to Eisenmenger syndrome (ES) makes the surgery complicated. Based on bidirectional cardiac shunting, vegetation easily develops in case of bacterial infection. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000017044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739013PMC
September 2019
4 Reads

Outcome after heart-lung or lung transplantation in patients with Eisenmenger syndrome.

Heart 2020 Jan 21;106(2):127-132. Epub 2019 Aug 21.

Department of Cardiology, Rigshospitalet, Copenhagen, Denmark.

Objective: The optimal timing for transplantation is unclear in patients with Eisenmenger syndrome (ES). We investigated post-transplantation survival and transplantation-specific morbidity after heart-lung transplantation (HLTx) or lung transplantation (LTx) in a cohort of Nordic patients with ES to aid decision-making for scheduling transplantation.

Methods: We performed a retrospective, descriptive, population-based study of patients with ES who underwent transplantation from 1985 to 2012. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/heartjnl-2019-315345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993032PMC
January 2020
6 Reads

Voice hoarseness in a patient with underlying Eisenmenger's syndrome: a case report.

J Otolaryngol Head Neck Surg 2019 Aug 19;48(1):38. Epub 2019 Aug 19.

College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada.

Background: The natural history of patients diagnosed with Eisenmenger's Syndrome typically revolve around the pediatric population. Medical advances have allowed these patients to live longer and present with a different subset of symptoms as a result of the progression of their disease process.

Case Presentation: In this case report, we discuss a 77-year-old Caucasian female with Eisenmenger's Syndrome presenting with hoarseness. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40463-019-0358-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700763PMC
August 2019
6 Reads

Guideline implementation and early risk assessment in pulmonary arterial hypertension associated with congenital heart disease: A retrospective cohort study.

Clin Respir J 2019 Nov 29;13(11):693-699. Epub 2019 Aug 29.

Congenital Heart Disease Center, Wuhan Asia Heart Hospital, Wuhan University of Science and Technology, Wuhan, China.

Introduction: Current guidelines emphasize that accurate risk stratification is important for patients with pulmonary arterial hypertension (PAH), however, few suggestions have been specified for PAH associated with congenital heart disease (PAH-CHD).

Objectives: The aim of this study was to propose an accurate and simple system based on current guidelines for risk stratification in PAH-CHD patients during 12-month follow-up.

Methods: We reviewed 288 Chinese PAH-CHD patients between January 2014 and December 2016 in this retrospective cohort study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/crj.13076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899897PMC
November 2019
2 Reads

The effects of parenteral prostacyclin therapy as add-on treatment to oral compounds in Eisenmenger syndrome.

Eur Respir J 2019 11 21;54(5). Epub 2019 Nov 21.

Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, Royal Brompton Hospital, London, UK

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1183/13993003.01401-2019DOI Listing
November 2019
4 Reads

Adult congenital heart disease with pulmonary arterial hypertension: mechanisms and management.

Heart Fail Rev 2019 Aug 12. Epub 2019 Aug 12.

Department of Cardiology, Larissa University General Hospital, P.O. Box 1425, 411 10, Larissa, Greece.

Adult congenital heart disease (ACHD) encompasses a range of structural cardiac abnormalities present before birth attributable to abnormal foetal cardiac development. The pulmonary circulation of patients with ACHD and intracardiac or extracardiac defects is often exposed to increased blood flow and occasionally to systemic pressures. Depending on the location and magnitude of the defect as well as the time of surgical correction, the patient with ACHD is at risk of developing pulmonary arterial hypertension (PAH), which dramatically increases morbidity and mortality. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10741-019-09847-5DOI Listing
August 2019
3 Reads

A single-centre, placebo-controlled, double-blind randomised cross-over study of nebulised iloprost in patients with Eisenmenger syndrome: A pilot study.

Int J Cardiol 2020 01 4;299:131-135. Epub 2019 Jul 4.

Adult Congenital Heart Disease Centre and National Centre for Pulmonary Hypertension, Royal Brompton Hospital London, United Kingdom; National Heart and Lung Institute, Imperial College, London, United Kingdom. Electronic address:

Background: Pulmonary arterial hypertension (PAH), is a rare and progressive disease with a high morbidity and mortality. Prostanoid pulmonary vasodilators are the most effective treatment for idiopathic and connective tissue associated PAH. Nonetheless, data examining their safety and efficacy in patients with Eisenmenger syndrome the most severe form of PAH, that is, related to cyanotic congenital heart disease (CHD-PAH) remains limited. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2019.07.004DOI Listing
January 2020
5 Reads

[Analysis of hemodynamics and outcomes of pregnant women with congenital heart disease-pulmonary arterial hypertension].

Authors:
L L Zhang J Zhang

Zhonghua Fu Chan Ke Za Zhi 2019 Jul;54(7):438-444

Department of Obstetrics and Gynecology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China.

To observe and analysis the changes of hemodynamic parameters and outcomes of pregnant women combined with congenital heart disease-pulmonary arterial hypertension (CHD-PAH). A prospective analysis of hemodynamic parameters of patients combined with CHD-PAH in Beijing Anzhen Hospital from January 2015 to December 2017 was carried out. Total 99 cases were divided into 4 groups based on systolic pulmonary arterial pressure (SPAP): mild group (SPAP 25-49 mmHg, 1 mmHg=0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.issn.0529-567x.2019.07.002DOI Listing
July 2019
4 Reads

Clinical course in children and adolescents with ventricular septal defect.

Asian Cardiovasc Thorac Ann 2019 Sep 30;27(7):529-534. Epub 2019 Jul 30.

Children & Adolescent Health Research Center, Resistant Tuberculosis Institute, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0218492319867001DOI Listing
September 2019
1 Read

Lung Perfusion Scintigraphy in Eisenmenger Syndrome Due to Patent Ductus Arteriosus.

Clin Nucl Med 2019 Nov;44(11):879-880

From the Department of Diagnostic Radiology, Kitasato University School of Medicine, Kanagawa, Japan.

Eisenmenger syndrome refers to the elevation of pulmonary arterial pressure to the systemic level caused by an increased pulmonary vascular resistance with right-to-left shunt through an intracardiac or aortopulmonary communication. A 36-year-old woman with Eisenmenger syndrome due to patent ductus arteriosus underwent Tc-MAA lung perfusion scintigraphy to evaluate right-to-left shunt. Whole-body imaging visualized extrapulmonary activity in both kidneys, spleen, and intestinal tract, confirming the presence of right-to-left shunt. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/RLU.0000000000002735DOI Listing
November 2019
2 Reads

Management of a young patient with dextrocardia, atrial septal defect, and Eisenmenger syndrome with venous-venous extracorporeal membrane oxygenation and heart-lung transplantation.

J Card Surg 2019 Oct 23;34(10):1114-1116. Epub 2019 Jul 23.

Division of Cardiac Surgery, Brigham and Women's Hospital, Boston, Massachusetts.

Dextrocardia is a rare congenital condition which presents important challenges for surgical management. We discuss a patient with dextrocardia, atrial septal defect, and Eisenmenger syndrome, which ultimately led to decompensated end-stage lung disease and heart-lung transplant. Venous-venous extracorporeal membrane oxygenation was an important strategy to bridge the patient until donor organs became available. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jocs.14168DOI Listing
October 2019
4 Reads

Operable ventricular septal defect despite severe pulmonary hypertension and cyanosis!

Cardiol Young 2019 Jul 23;29(7):986-988. Epub 2019 Jul 23.

Departments of Cardiology, and Cardiothoracic surgery, All India Institute of Medical Sciences, New Delhi, India.

Patients with a significant left-to-right shunt at ventricular level may become inoperable at an early age due to irreversible pulmonary vascular disease. On the other hand, even suprasystemic pulmonary hypertension due to mitral stenosis remains treatable. We report a 24-year-old patient with large ventricular septal defect, severe mitral stenosis and cyanosis who improved after surgical correction of both the lesions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S1047951119001057DOI Listing
July 2019
3 Reads

Paradoxical intraoperative embolism in a patient with Eisenmenger syndrome undergoing hip arthroplasty.

Rev Esp Anestesiol Reanim 2019 Oct 18;66(8):439-442. Epub 2019 Jul 18.

Servicio de Anestesiología y Reanimación, Hospital Universitario Virgen de la Nieves, Granada, España.

Hip arthroplasty is associated with a high incidence of embolic events that, although usually not relevant at a clinical level, may be an important cause of morbidity and mortality in certain situations. Extreme caution should be taken in patients with cardiac defects that favor communication between the pulmonary and systemic circulation, due to their greater risk of complications. We present the case of a 72-year-old patient who suffered a paradoxical embolism during the intervention, with devastating consequences. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.redar.2019.03.014DOI Listing
October 2019
4 Reads

Emergent Decompression of Intracranial Abscess in Eisenmenger Syndrome.

World Neurosurg 2019 Oct 8;130:133-137. Epub 2019 Jul 8.

Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA. Electronic address:

Background: Eisenmenger syndrome is a rare sequela of uncorrected congenital heart disease complicated by pulmonary hypertension, from which reversal of the pathologic left-to-right cardiovascular shunt and cyanosis follow. Right-to-left shunting can lead to paradoxical cerebral emboli-increasing the risk of spontaneous or iatrogenic stroke and cerebral abscess.

Case Description: A 38-year-old man presented with new focal seizures due to a brain abscess. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2019.07.010DOI Listing
October 2019
11 Reads

Incidence of Massive Transfusion and Overall Transfusion Requirements During Lung Transplantation Over a 25-Year Period.

J Cardiothorac Vasc Anesth 2019 Sep 30;33(9):2478-2486. Epub 2019 Mar 30.

Department of Anesthesiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Objective: To establish the incidence of massive transfusion and overall transfusion requirements during lung transplantation, changes over time, and association with outcome in relation to patient complexity.

Design: Retrospective cohort study.

Setting: University hospital. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.jvca.2019.03.060DOI Listing
September 2019
14 Reads

Eisenmenger syndrome and other types of pulmonary arterial hypertension related to adult congenital heart disease.

Expert Rev Cardiovasc Ther 2019 Jun 6;17(6):449-459. Epub 2019 Jun 6.

a Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension , National Heart and Lung Institute, Biomedical Research Unit, Royal Brompton Hospital, Imperial College , London , UK.

: Eisenmenger syndrome (ES) is the most advanced form of pulmonary arterial hypertension (PAH) in patients with congenital heart disease (CHD). It is characterised by a severe rise in pulmonary vascular resistance resulting in shunt reversal and cyanosis. : In this paper, an overview of ES and other types of PAH related to CHD (PAH-CHD) in adults is provided. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/14779072.2019.1
Publisher Site
http://dx.doi.org/10.1080/14779072.2019.1623024DOI Listing
June 2019
13 Reads

Aortopulmonary window in adults: A rare entity leading to Eisenmenger syndrome.

Echocardiography 2019 06 22;36(6):1173-1178. Epub 2019 May 22.

Department of Pediatrics and Adolescent Medicine, American University of Beirut Medical Center, Beirut, Lebanon.

An aortopulmonary window (APW) is a rare congenital heart defect involving an abnormal communication between the ascending aorta and the pulmonary trunk with separate aortic and pulmonary valves. This defect accounts for 0.2% of all congenital cardiac anomalies and if left untreated can lead to Eisenmenger syndrome, severe pulmonary hypertension, heart failure, and poor survival. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/echo.14368DOI Listing
June 2019
10 Reads