3,182 results match your criteria Ehrlichiosis


Molecular characterization of Anaplasma and Ehrlichia in ixodid ticks and reservoir hosts from Palestine: a pilot survey.

Vet Med Sci 2019 Feb 14. Epub 2019 Feb 14.

Al-Quds Public Health Society, East Jerusalem, Palestine.

Tick-borne anaplasmosis and ehrlichiosis are clinically important emerging zoonoses usually overlooked by veterinarians and physicians alike. This study aimed at detecting and genetically characterizing Ehrlichia and Anaplasma species in ixodid ticks and their animal hosts from the West Bank, Palestine. A total of 723 ixodid ticks belonging to three genera (Rhipicephalus, Hyalomma, Haemaphysalis) were collected from dogs, sheep, goats and camels. Read More

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http://dx.doi.org/10.1002/vms3.150DOI Listing
February 2019

Prevalence of Borrelia burgdorferi, Anaplasma spp., Ehrlichia spp. and Dirofilaria immitis in Canadian dogs, 2008 to 2015: a repeat cross-sectional study.

Parasit Vectors 2019 Jan 28;12(1):64. Epub 2019 Jan 28.

University of Guelph, Guelph, Ontario, N1G 2W1, Canada.

Background: Vector-borne pathogens are emerging concerns in multiple regions of Canada. Determining regional prevalence of canine vector-borne pathogens and documenting change will improve clinician awareness, enable targeted prevention, enhance diagnosis and ideally reduce the risk of disease. Study objectives were to: (i) estimate the prevalence of positive canine vector-borne test results from samples submitted in Canada; (ii) assess change in prevalence over time, from baseline (2008) to 2015; and (iii) estimate the prevalence of pathogen co-infections. Read More

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https://parasitesandvectors.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13071-019-3299-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350403PMC
January 2019
5 Reads

First detection of Ehrlichia minasensis in Hyalomma marginatum ticks collected from cattle in Corsica, France.

Vet Med Sci 2019 Jan 21. Epub 2019 Jan 21.

EA7310 BIOSCOPE, Laboratoire de Virologie, Université de Corse-Inserm, Corte, France.

Ehrlichiosis are severe, feverish tick-borne illnesses caused by specific species within the genus Ehrlichia (Anaplasmataceae family). Recent data suggest that ruminants in Corsica area reservoir for several Anaplasmataceae species. The purpose of our study was to determine whether Ehrlichia species could be detected in ticks collected in Corsican ruminants by using molecular methods. Read More

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http://dx.doi.org/10.1002/vms3.140DOI Listing
January 2019

Molecular characterization of Ehrlichia canis from naturally infected dogs from the state of Rio de Janeiro.

Braz J Microbiol 2019 Jan 11;50(1):1-12. Epub 2018 Dec 11.

Department of Animal Parasitology, Veterinary Institute, Federal Rural University of Rio de Janeiro, BR 465, km 7, Seropédica, Rio de Janeiro, 23890-000, Brazil.

The aim of the present study was to evaluate the genetic diversity of Ehrlichia canis in naturally infected dogs from six mesoregions of Rio de Janeiro state. E. canis was diagnosed with a real-time polymerase chain reaction (qPCR) targeting a 93 base pair (bp) fragment of the 16S rDNA gene. Read More

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http://dx.doi.org/10.1007/s42770-018-0020-7DOI Listing
January 2019
8 Reads

Molecular Detection and Phylogenetic Analysis of Anaplasma phagocytophilum in Horses in Korea.

Korean J Parasitol 2018 Dec 31;56(6):559-565. Epub 2018 Dec 31.

College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Korea.

The identification and characterization of pathogenic and zoonotic tick-borne diseases like granulocytic anaplasmosis are essential for developing effective control programs. The differential diagnosis of pathogenic Anaplasma phagocytophilum and non-pathogenic A. phagocytophilum-like Anaplasma spp. Read More

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http://parasitol.kr/journal/view.php?doi=10.3347/kjp.2018.56
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http://dx.doi.org/10.3347/kjp.2018.56.6.559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327205PMC
December 2018
5 Reads

Molecular identification of Ehrlichia ewingii in a polyarthritic Texas dog.

Vet Clin Pathol 2019 Jan 9. Epub 2019 Jan 9.

Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, College Station, Texas.

An 8-year-old, neutered male, Golden Retriever presented for bilateral carpal joint effusion. A complete blood count revealed mild leukopenia and marked thrombocytopenia. Samples were sent to the Texas A&M Veterinary Medical Diagnostic Laboratory for blood smear review and serologic testing for tick-borne diseases. Read More

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http://doi.wiley.com/10.1111/vcp.12690
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http://dx.doi.org/10.1111/vcp.12690DOI Listing
January 2019
11 Reads

Evidence of in Argentina through molecular detection in marsh deer ().

Int J Parasitol Parasites Wildl 2019 Apr 17;8:45-49. Epub 2018 Dec 17.

Instituto de Biotecnología, Instituto Nacional de Tecnología Agropecuaria (INTA), Las Cabañas y Los Reseros s/n (B1712WAA), Castelar, Buenos Aires, Argentina.

Vector-borne pathogens are responsible for serious emerging diseases and have been widely described in wildlife. causes the zoonotic "monocytic ehrlichiosis" in humans, is transmitted by the tick and its reservoir host is the white-tailed deer () in North America. Little is known about the native reservoir and the tick vectors involved in the transmission cycle in South America. Read More

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http://dx.doi.org/10.1016/j.ijppaw.2018.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312859PMC

Low genetic diversity of Ehrlichia canis associated with high co-infection rates in Rhipicephalus sanguineus (s.l.).

Parasit Vectors 2019 Jan 7;12(1):12. Epub 2019 Jan 7.

UMR BIPAR, INRA, ANSES, Ecole Nationale Vétérinaire d'Alfort, Université Paris-Est, 94700, Maisons-Alfort, France.

Background: Rhipicephalus sanguineus sensu lato (s.l.) is the most widely distributed ixodid tick and is a vector of major canine and human pathogens. Read More

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https://parasitesandvectors.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13071-018-3194-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322249PMC
January 2019
11 Reads
3.430 Impact Factor

Clinicopathological findings in 41 dogs (2008-2018) naturally infected with Ehrlichia ewingii.

J Vet Intern Med 2019 Jan 2. Epub 2019 Jan 2.

Vector Borne Disease Diagnostic Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina.

Background: Ehrlichia ewingii is the most seroprevalent Ehrlichia-infecting dogs in the southern and mid-western United States. Fever, lameness, and polyarthritis are commonly reported findings in dogs naturally infected with E. ewingii. Read More

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http://dx.doi.org/10.1111/jvim.15354DOI Listing
January 2019
2 Reads

Ehrlichia ruminantium antigens and peptides induce cytotoxic T cell responses in vitro.

Vet Immunol Immunopathol 2019 Jan 19;207:1-9. Epub 2018 Nov 19.

Agricultural Research Council-Onderstepoort Veterinary Research, Private Bag X5, Onderstepoort 0110, South Africa; Department of Veterinary Tropical Diseases, Veterinary Faculty, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa.

Since CD8 T cells play an important role in resistance to infection with heartwater, effective vaccines against this disease will likely require identification of antigens that contain CD8 T cell epitopes responsible for cytotoxic T lymphocyte (CTL) responses. With the use of the fluorescent antigen-transfected target cell (FATT)-CTL assay, IFN-γ ELISPOT and flow cytometry, peptides that induce CTL, proliferation of CD8 + T cells and IFN-γ production were identified as possible target antigens for vaccine development. Of particular relevance was the finding that different peptides from different antigens were able to elicit varied cytotoxic activities by immune peripheral blood mononuclear cells (PBMC) from heartwater immune tick-infected sheep. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01652427183029
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http://dx.doi.org/10.1016/j.vetimm.2018.11.012DOI Listing
January 2019
6 Reads

Prevalence of Ehrlichia canis (Rickettsiales: Ehrlichieae) DNA in Tissues From Rhipicephalus sanguineus (Acari: Ixodidae) Ticks in Areas Endemic for Canine Monocytic Ehrlichiosis in Brazil.

J Med Entomol 2018 Dec 19. Epub 2018 Dec 19.

Universidade Estadual Paulista (Unesp), Faculdade de Medicina Veterinária de Araçatuba, Dona Amélia, Araçatuba, Brazil.

Canine monocytic ehrlichiosis (CME) is a disease caused by the obligate intracellular bacterium Ehrlichia canis. Tropical lineages of Rhipicephalus sanguineus ticks play an essential role in the transmission of this pathogen. The aim of the present study was to evaluate the prevalence of E. Read More

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http://dx.doi.org/10.1093/jme/tjy220DOI Listing
December 2018

Comparative Evaluation of 2 In-Clinic Assays for Vector-Borne Disease Testing in Dogs.

Top Companion Anim Med 2018 Dec 13;33(4):114-118. Epub 2018 Sep 13.

Assay R&D, IDEXX Laboratories Inc, Westbrook, ME, USA. Electronic address:

Vector-borne agents comprise medically important infections affecting dogs throughout much of the world. Sensitive detection of antibodies directed at tick-borne disease-causing organisms in dogs is diagnostically important for veterinarians, pets and their owners, and epidemiologically important for public health surveillance. The SNAP 4Dx Plus Test (IDEXX Laboratories, Inc. Read More

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http://dx.doi.org/10.1053/j.tcam.2018.09.003DOI Listing
December 2018
5 Reads

Isolation and molecular detection of Ehrlichia species from ticks in western, central, and eastern Japan.

Ticks Tick Borne Dis 2019 02 13;10(2):344-351. Epub 2018 Nov 13.

United Graduate School of Agricultural Science and Veterinary Science, Gifu University, Gifu, Japan; Department of Virology 1, National Institute of Infectious Diseases, Tokyo, Japan.

Ehrlichiosis is a tick-borne bacterial disease caused by pathogens of the Ehrlichia genus. Although human ehrlichiosis has not been reported in Japan, Ehrlichia spp., which are closely related to Ehrlichia chaffeensis, were detected in several species of ixodid ticks. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2018.11.010DOI Listing
February 2019
1 Read

PCR sensitivity of peripheral blood of dogs co-infected with Leishmania spp. and Ehrlichia spp. in endemic area of Brazil.

Rev Soc Bras Med Trop 2018 Nov-Dec;51(6):843-847

Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal da Grande Dourados , Dourados, MS, Brasil.

Introduction: Peripheral blood of 400 dogs infected with Leishmania and Ehrlichia were analyzed using polymerase chain reaction (PCR), and clinical signs were characterized.

Methods: PCR and parasitological tests were conducted.

Results: PCR was positive for Leishmania in 84. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
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http://dx.doi.org/10.1590/0037-8682-0040-2018DOI Listing
February 2019
7 Reads

Repeated cross-sectional study of Trypanosoma cruzi in shelter dogs in Texas, in the context of Dirofilaria immitis and tick-borne pathogen prevalence.

J Vet Intern Med 2019 Jan 29;33(1):158-166. Epub 2018 Nov 29.

Department of Veterinary Integrative Biosciences, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, Texas.

Background: Vector-borne diseases have an adverse impact on health of dogs, and infected dogs can be sentinels for human infection. Infection with Trypanosoma cruzi, an agent of Chagas disease, causes fatal heart disease in dogs across the southern United States but has been neglected from wide-scale prevalence studies.

Objectives: To determine the prevalence of exposure to T. Read More

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http://dx.doi.org/10.1111/jvim.15352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335532PMC
January 2019
8 Reads

Role of mustelids in the life-cycle of ixodid ticks and transmission cycles of four tick-borne pathogens.

Parasit Vectors 2018 Nov 20;11(1):600. Epub 2018 Nov 20.

Centre for Zoonoses and Environmental Microbiology, Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.

Background: Elucidating which wildlife species significantly contribute to the maintenance of Ixodes ricinus populations and the enzootic cycles of the pathogens they transmit is imperative in understanding the driving forces behind the emergence of tick-borne diseases. Here, we aimed to quantify the relative contribution of four mustelid species in the life-cycles of I. ricinus and Borrelia burgdorferi (sensu lato) in forested areas and to investigate their role in the transmission of other tick-borne pathogens. Read More

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http://dx.doi.org/10.1186/s13071-018-3126-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245527PMC
November 2018
2 Reads

Investigation of the tick-borne pathogens Rickettsia helvetica and Anaplasma phagocytophilum in the blood of the domestic goat (Capra hircus).

Authors:
A Rymaszewska

Pol J Vet Sci 2018 Jun;21(2):415-417

Department of Genetics, University of Szczecin, Felczaka 3C, 71-412 Szczecin, Poland.

The bacterial species Anaplasma phagocytophilum and Rickettsia helvetica are pathogenic for humans and domestic animals and are transmitted by ticks, e.g., of the Ixodes genus. Read More

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http://dx.doi.org/10.24425/122607DOI Listing
June 2018
1 Read

Ehrlichiosis presenting as severe sepsis and meningoencephalitis in an immunocompetent adult.

JMM Case Rep 2018 Sep 27;5(9):e005162. Epub 2018 Jul 27.

Department of Pharmacy Practice and Science, University of Kentucky College of Pharmacy, Lexington, KY, USA.

Introduction: are obligate intracellular pathogens transmitted to vertebrates by ticks.

Case Presentation: We report the case of a 59-year-old man who presented to the University of Kentucky Albert B. Chandler Medical Center (Lexington, KY, USA) after being found fallen down in the woods. Read More

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http://dx.doi.org/10.1099/jmmcr.0.005162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230758PMC
September 2018
3 Reads

Seroprevalence and current infections of canine vector-borne diseases in Nicaragua.

Parasit Vectors 2018 Nov 12;11(1):585. Epub 2018 Nov 12.

Institute for Parasitology, Centre for Infection Medicine, University of Veterinary Medicine Hannover, Buenteweg 17, 30559, Hannover, Germany.

Background: Vector-borne diseases constitute a major problem for veterinary and public health, especially in tropical regions like Central America. Domestic dogs may be infected with several vector-borne pathogens of zoonotic relevance, which may also severely compromise canine health.

Methods: To assess the prevalence of canine vector-borne diseases in Nicaragua, 329 dogs from seven cities, which were presented to the veterinarian for various reasons, were included in this study. Read More

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https://parasitesandvectors.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13071-018-3173-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233566PMC
November 2018
7 Reads

Survey and Phylogenetic Analysis of Rodents and Important Rodent-Borne Zoonotic Pathogens in Gedu, Bhutan.

Korean J Parasitol 2018 Oct 31;56(5):521-525. Epub 2018 Oct 31.

International Development Group, School of Veterinary Science, Massey University, Palmerston North, New Zealand.

Rodents are well-known reservoirs and vectors of many emerging and re-emerging infectious diseases, but little is known about their role in zoonotic disease transmission in Bhutan. In this study, a cross-sectional investigation of zoonotic disease pathogens in rodents was performed in Chukha district, Bhutan, where a high incidence of scrub typhus and cases of acute undifferentiated febrile illness had been reported in people during the preceding 4-6 months. Twelve rodents were trapped alive using wire-mesh traps. Read More

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http://parasitol.kr/journal/view.php?doi=10.3347/kjp.2018.56
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http://dx.doi.org/10.3347/kjp.2018.56.5.521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243181PMC
October 2018
14 Reads

The relationship between ehrlichiosis and the development of hematologic malignancies.

Med Hypotheses 2018 Dec 14;121:57-59. Epub 2018 Sep 14.

Rush University Medical Center, Division of Hematology/Oncology and Cell Therapy, 1725 W. Harrison, Suite 809, Chicago, IL 60612, United States. Electronic address:

Viral and bacterial infections cause chronic inflammation and produce bacterial metabolites that may lead to carcinogenesis. Ehrlichiosis is an intracellular infection that primarily infects white blood cells. Given that infections can lead to cancer, and that Ehrlichia has tropism for white blood cells, it can be deduced that Ehrlichia may cause hematologic malignancies, such as acute leukemia. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03069877183047
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http://dx.doi.org/10.1016/j.mehy.2018.09.026DOI Listing
December 2018
7 Reads

Current Status of Tick-Borne Diseases in South Korea.

Vector Borne Zoonotic Dis 2018 Oct 17. Epub 2018 Oct 17.

1 Department of Internal Medicine and Inha University School of Medicine , Incheon, Republic of Korea.

Background: Bites with tick-borne pathogens can cause various bacterial, viral, or parasitic diseases in humans. Tick-transmitted diseases are known as contributing factors to the increasing incidence and burden of diseases. The present article investigated the epidemiology of tick-borne diseases in South Korea. Read More

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http://dx.doi.org/10.1089/vbz.2018.2298DOI Listing
October 2018
4 Reads

Prevalence of canine Babesia and Ehrlichia co-infection and the predictive value of haematology.

Onderstepoort J Vet Res 2018 Oct 9;85(1):e1-e5. Epub 2018 Oct 9.

Department of Companion Animal Clinical Studies, University of Pretoria.

Canine babesiosis and ehrlichiosis are important tick-borne infections in South Africa. Many South African general veterinary practitioners perceive co-infection with Ehrlichia spp. as a common occurrence in dogs with babesiosis. Read More

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http://dx.doi.org/10.4102/ojvr.v85i1.1626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324083PMC
October 2018
5 Reads

Epidemiology of Ehrlichia canis in healthy dogs from the Southeastern region of the state of Rio de Janeiro, Brazil.

Prev Vet Med 2018 Nov 14;159:135-142. Epub 2018 Sep 14.

Department of Epidemiology and Public Health, Veterinary Institute, Federal Rural University of Rio de Janeiro, Br 465, km 7, Seropedica, Rio de Janeiro, 23897-000, Brazil. Electronic address:

This cross-sectional, observational, and descriptive study aims to investigate the epidemiology of Ehrlichia canis in healthy owned dogs from the Southeastern region of Rio de Janeiro, Brazil. Blood samples were collected from 390 households dogs. During the visits, an epidemiological questionnaire was filled out concerning the dogs' characteristics as well as the environments in which they lived. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01675877183032
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http://dx.doi.org/10.1016/j.prevetmed.2018.09.012DOI Listing
November 2018
6 Reads

Ehrlichiosis masquerading as thrombotic thrombocytopenic purpura.

BMJ Case Rep 2018 Oct 2;2018. Epub 2018 Oct 2.

Department of Pulmonary and Critical Care Medicine, University of Louisville, Louisville, Kentucky, USA.

Ehrlichiosis is a rare tickborne illness that can manifest from an asymptomatic, self-limiting disease to a severe presentation with encephalopathy and renal failure. Ehrlichiosis is diagnosed largely based on patient history with confirmatory tests including peripheral blood smear, serology and PCR. Empiric treatment is warranted in patients with suspected tick bites as a delay in treatment can result in multiorgan failure. Read More

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http://dx.doi.org/10.1136/bcr-2018-226665DOI Listing
October 2018
8 Reads

Development and Clinical Validation of a Multiplex Real-Time Quantitative PCR Assay for Human Infection by Anaplasma phagocytophilum and Ehrlichia chaffeensis.

Trop Med Infect Dis 2018 Jan 29;3(1). Epub 2018 Jan 29.

Joint Departments of Pathology, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Walter Reed National Military Medical Center, Joint Pathology Center, Bethesda, MD 20814, USA.

Background: Human granulocytic anaplasmosis (HGA), caused by , and human monocytic ehrlichiosis (HME), caused by , often present as undifferentiated fever but are not treated by typical empiric regimens for acute febrile illness. Their role as agents of vector-borne febrile disease in tropical regions is more poorly studied than for other rickettsial infections. Limitations in diagnosis have impaired epidemiologic and clinical research and needless morbidity and mortality occur due to untreated illness. Read More

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http://www.mdpi.com/2414-6366/3/1/14
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http://dx.doi.org/10.3390/tropicalmed3010014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136628PMC
January 2018
6 Reads

Large-scale health disparities associated with Lyme disease and human monocytic ehrlichiosis in the United States, 2007-2013.

PLoS One 2018 27;13(9):e0204609. Epub 2018 Sep 27.

Department of Ecology and Evolutionary Biology, University of Colorado, Boulder, Colorado, United States of America.

Promoting health equity is a fundamental public health objective, yet health disparities remain largely overlooked in studies of vectorborne diseases, especially those transmitted by ticks. We sought to identify health disparities associated with Lyme disease and human monocytic ehrlichiosis, two of the most pervasive tickborne diseases within the United States. We used general linear mixed models to measure associations between county-level disease incidence and six variables representing racial/ethnic and socioeconomic characteristics of counties (percent white non-Hispanic; percent with a bachelors degree or higher; percent living below the poverty line; percent unemployed; percent of housing units vacant; per capita number of property crimes). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0204609PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160131PMC
September 2018
1 Read

Continued expansion of tick-borne pathogens: Tick-borne encephalitis virus complex and Anaplasma phagocytophilum in Denmark.

Ticks Tick Borne Dis 2019 01 17;10(1):115-123. Epub 2018 Sep 17.

Clinical Centre for Emerging and Vector-borne Infections, Odense University Hospital, Sdr. Boulevard 29, DK-5000, Odense C, Denmark; Department of Infectious diseases, Odense University Hospital, Sdr. Boulevard 29, DK-5000, Odense C, Denmark. Electronic address:

Tick-borne encephalitis virus (TBEV) is a tick-transmitted flavivirus within the tick-borne encephalitis (TBE) complex. The TBE complex is represented by both TBEV and louping ill virus (LIV) in Denmark. Anaplasma phagocytophilum is also transmitted by ticks and is believed to play an essential role in facilitating and aggravating LIV infection in sheep. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2018.09.007DOI Listing
January 2019

Prevalence of Canine Monocytic Ehrlichiosis in Canine Population Across India.

Arch Razi Inst 2018 Jun 1;73(2):87-93. Epub 2018 Mar 1.

Biotechnology Section, Central Military Veterinary Laboratory, remount Veterinary Corps, Meerut Cantt, Uttar Pradesh, 250001, India.

Canine ehrlichiosis is a very important emerging disease in India. This study is the first attempt screening a large number of canines in India for the detection of canine monocytic ehrlichiosis. In the present study, 510 blood samples of dogs were screened for the presence of Ehrlichia canis and other variants of Anaplasmataceae family by serological and molecular methods. Read More

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http://dx.doi.org/10.22092/ari.2018.116616DOI Listing

Exposure to Ticks and their Pathogens in Northeast Missouri.

Authors:
Deborah A Hudman

Mo Med 2018 Jul-Aug;115(4):374-379

Deborah A. Hudman, MS, is in the Department of Microbiology/Immunology, A.T. Still University Kirksville College of Osteopathic Medicine.

While the prevalence of human pathogens has been quantified in ticks in Adair County, Missouri, the prevalence of residents acquiring tick-borne diseases and seeking medical treatment has not. A public survey (n=109) revealed that 96% of respondents reported finding attached ticks on their person; of these, 38% developed symptoms post tick bite; of these, 55% reported consultation with a health care provider. Overall, 89% of practitioners surveyed had treated at least one patient for tick-borne disease. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140261PMC
September 2018
5 Reads

Successful Infection of Tick Cell Cultures of Rhipicephalus sanguineus (Tropical Lineage) with Ehrlichia canis.

Vector Borne Zoonotic Dis 2018 Sep 17. Epub 2018 Sep 17.

6 Federal University of Uberlândia , Uberlândia, Brazil .

There are two distinct lineages of ticks, Rhipicephalus sanguineus, in South America: tropical and temperate lineages. Only the tropical lineage is recognized as competent vector for Ehrlichia canis. The epidemiological data of canine monocytic ehrlichiosis is congruent with the distribution of the two lineages of R. Read More

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http://dx.doi.org/10.1089/vbz.2017.2197DOI Listing
September 2018

Identification of novel immunoreactive proteins and delineation of a specific epitope of Anaplasma phagocytophilum.

Microb Pathog 2018 Dec 11;125:183-188. Epub 2018 Sep 11.

Department of Microbiology, College of Medicine, Soochow University, Suzhou, Jiangsu Province, 215123, China. Electronic address:

Human granulocytic anaplasmosis (HGA), an increasingly recognized febrile tick-borne illness, is caused by a gram-negative obligate intracellular bacterium Anaplasma phagocytophilum. Because of nonspecific clinical manifestations, diagnosis of HGA highly depends on laboratory tests. Identification of immunoreactive proteins is prerequisite for development of specific and sensitive immunoassays for HGA. Read More

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http://dx.doi.org/10.1016/j.micpath.2018.09.017DOI Listing
December 2018
1 Read
2.000 Impact Factor

Molecular detection and characterization of tick-borne protozoan and rickettsial pathogens isolated from cattle on Pemba Island, Tanzania.

Ticks Tick Borne Dis 2018 09 4;9(6):1437-1445. Epub 2018 Jul 4.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, 080-8555, Japan. Electronic address:

Tick-borne diseases cause significant losses to livestock production in tropical and subtropical regions. In Tanzania, detailed studies on tick-borne pathogens in cattle using sensitive molecular detection methods are scarce. In this study, we investigated the occurrence of Theileria spp. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2018.06.014DOI Listing
September 2018
3 Reads

Tick-borne zoonoses in the Order Rickettsiales and Legionellales in Iran: A systematic review.

PLoS Negl Trop Dis 2018 09 11;12(9):e0006722. Epub 2018 Sep 11.

Department of Pathobiology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.

Background: Tick-borne zoonoses in the Order Rickettsiales and Legionellales cause infections that often manifest as undifferentiated fevers that are not easy to distinguish from other causes of acute febrile illnesses clinically. This is partly attributed to difficulty in laboratory confirmation since convalescent sera, specific diagnostic reagents, and the required expertise may not be readily available. As a result, a number of tick-borne zoonoses are underappreciated resulting in unnecessary morbidity, mortality and huge economic loses. Read More

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https://dx.plos.org/10.1371/journal.pntd.0006722
Publisher Site
http://dx.doi.org/10.1371/journal.pntd.0006722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181433PMC
September 2018
29 Reads

Some aspects on tick species in Mongolia and their potential role in the transmission of equine piroplasms, Anaplasma phagocytophilum and Borrelia burgdorferi L.

Parasitol Res 2018 Nov 3;117(11):3557-3566. Epub 2018 Sep 3.

Institute of Parasitology, Department of Pathobiology, University of Veterinary Medicine Vienna, Veterinaerplatz 1, 1210, Wien, Austria.

Ticks are cosmopolitan vectors of numerous diseases, and detection of various pathogens in ticks can help to assess their distribution. In the current study, 528 adult ticks were collected from grazing animals or the ground in ten different Mongolian provinces. Dermacentor nuttalli constituted 76. Read More

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http://dx.doi.org/10.1007/s00436-018-6053-xDOI Listing
November 2018
4 Reads

Tick-Borne Illnesses in the United States.

Prim Care 2018 Sep 9;45(3):379-391. Epub 2018 Jul 9.

Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic, 4500 San Pablo Road S, Jacksonville, FL 32224, USA.

Close interaction with nature can lead to tick-borne illnesses, which are seen most frequently in primary care clinics when patients present symptoms. Considerable morbidity can result from untreated infections. Fortunately, these illnesses are often easily managed when diagnosed early. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00954543183004
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http://dx.doi.org/10.1016/j.pop.2018.05.011DOI Listing
September 2018
28 Reads

Type I IFNs drive hematopoietic stem and progenitor cell collapse via impaired proliferation and increased RIPK1-dependent cell death during shock-like ehrlichial infection.

PLoS Pathog 2018 08 6;14(8):e1007234. Epub 2018 Aug 6.

Department of Immunology and Microbial Disease, Albany Medical College, Albany, New York, United States of America.

Type I interferons (IFNα/β) regulate diverse aspects of host defense, but their impact on hematopoietic stem and progenitor cells (HSC/HSPCs) during infection remains unclear. Hematologic impairment can occur in severe infections, thus we sought to investigate the impact of type I IFNs on hematopoiesis in a tick-borne infection with a virulent ehrlichial pathogen that causes shock-like disease. During infection, IFNα/β induced severe bone marrow (BM) loss, blunted infection-induced emergency myelopoiesis, and reduced phenotypic HSPCs and HSCs. Read More

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https://dx.plos.org/10.1371/journal.ppat.1007234
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http://dx.doi.org/10.1371/journal.ppat.1007234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095620PMC
August 2018
7 Reads

Detection of Anaplasmataceae agents and co-infection with other tick-borne protozoa in dogs and Rhipicephalus sanguineus sensu lato ticks.

Exp Appl Acarol 2018 Aug 2;75(4):429-435. Epub 2018 Aug 2.

Tropical Infectious Diseases Research and Education Centre (TIDREC), University of Malaya, Kuala Lumpur, Malaysia.

Anaplasmosis and ehrlichiosis are of serious health concern worldwide for animals and humans. In the present study, we report the occurrence of Anaplasma platys and Ehrlichia canis in dogs and Rhipicephalus sanguineus sensu lato (s.l. Read More

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http://dx.doi.org/10.1007/s10493-018-0280-9DOI Listing
August 2018
1 Read
1.622 Impact Factor

Zoonotic Anaplasma phagocytophilum, Ehrlichia canis, Dirofilaria immitis, Borrelia burgdorferi, and spotted fever group rickettsiae (SFGR) in different types of dogs.

Parasitol Res 2018 Nov 31;117(11):3407-3412. Epub 2018 Jul 31.

Department of Veterinary Clinical Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, Irbid, 22110, Jordan.

Dogs can carry and share zoonotic pathogens with humans. This problem is understudied in different parts of the world, including Jordan. This study determined the prevalence of Anaplasma phagocytophilum, Ehrlichia canis, Dirofilaria immitis, and Borrelia burgdorferi using the SNAP 4Dx Plus test and spotted fever group rickettsiae (SFGR) using enzyme immunoassay IgG test in different types of dogs (farm/breeding, police, and stray) in Jordan. Read More

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http://link.springer.com/10.1007/s00436-018-6033-1
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http://dx.doi.org/10.1007/s00436-018-6033-1DOI Listing
November 2018
9 Reads

Diagnosing Meat Allergy After Tick Bite Without Delay.

J Am Board Fam Med 2018 Jul-Aug;31(4):650-652

From Jersey Shore University Medical Center, Neptune, NJ (ACK, MPC).

Galactose-α-1, 3 galactose (α-gal) is a carbohydrate found in mammalian meat. In 2007, it was implicated as a cause of severe hypersensitivity reactions when a study found elevated levels of antibodies directed against this oligosaccharide among patients treated with cetuximab, a monoclonal antibody that contained an α -gal epitope. The majority of these cases were reported in the Southeast United States in a distribution similar to that of Rocky Mountain spotted fever and ehrlichiosis, and that geographic association led researchers to the conclusion that a bite from the Lone Star tick can induce this antibody. Read More

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http://dx.doi.org/10.3122/jabfm.2018.04.170425DOI Listing
October 2017
9 Reads

Unexpected cause of fever in a patient with untreated HIV.

BMJ Case Rep 2018 Jul 3;2018. Epub 2018 Jul 3.

Department of Internal Medicine, Allegheny Health Network, Pittsburgh, Pennsylvania, USA.

We report a case of a 27-year-old man with a history of untreated HIV who presented with fever, rash and leg cramps. Initial suspicion was high for an infectious process; however, after an exhaustive evaluation, thyrotoxicosis was revealed as the aetiology of his symptoms. Recent intravenous contrast administration complicated his workup to determine the exact cause of hyperthyroidism. Read More

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http://dx.doi.org/10.1136/bcr-2018-225087DOI Listing
July 2018
21 Reads

Serological Evidence of Borrelia burgdorferi, Anaplasma phagocytophilum and Ehrlichia Spp. Infections in Horses from Southeastern Bulgaria.

Vector Borne Zoonotic Dis 2018 11 3;18(11):588-594. Epub 2018 Jul 3.

4 Department of Infectious Diseases, Military Medical Academy , Sofia, Bulgaria .

Lyme Borreliosis and granulocytic anaplasmosis are less extensively studied in horses than in dogs and humans. Equine ehrlichiosis is not known in Europe and is in the initial stage of investigation in South, Central, and North America. The aim of this study was to determine the seroprevalence of these infections in Bulgaria. Read More

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http://dx.doi.org/10.1089/vbz.2018.2293DOI Listing
November 2018
20 Reads

Molecular survey and characterization of Theileria annulata and Ehrlichia ruminantium in cattle from Northwest China.

Parasitol Int 2018 Dec 27;67(6):679-683. Epub 2018 Jun 27.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan. Electronic address:

Theileriosis and ehrlichiosis are two important tick-borne diseases affecting cattle farming in China. However, limited information is available regarding prevalence and molecular characterization of Theileria annulata and Ehrlichia ruminantium in cattle in Xinjiang Uygur Autonomous Region (XUAR), northwestern China. In this study, a total of 176 blood samples of cattle from three rural areas of XUAR were collected in June 2017 and were tested by nested-PCR. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13835769183008
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http://dx.doi.org/10.1016/j.parint.2018.06.011DOI Listing
December 2018
9 Reads

Serological reactivity to Anaplasma phagocytophilum in neoehrlichiosis patients.

Eur J Clin Microbiol Infect Dis 2018 Sep 14;37(9):1673-1678. Epub 2018 Jun 14.

Department of Infectious Diseases, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.

The tick-borne bacterium Candidatus (Ca.) Neoehrlichia (N.) mikurensis is a cause of "fever of unknown origin" because this strict intracellular pathogen escapes detection by routine blood cultures. Read More

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http://dx.doi.org/10.1007/s10096-018-3298-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133046PMC
September 2018
4 Reads

Protein and DNA synthesis demonstrated in cell-free Ehrlichia chaffeensis organisms in axenic medium.

Sci Rep 2018 Jun 18;8(1):9293. Epub 2018 Jun 18.

Center of Excellence for Vector-Borne Diseases, Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, 66506, USA.

Ehrlichia chaffeensis, a tick-transmitted rickettsial bacterium, is the causative agent of human monocytic ehrlichiosis. Biochemical characterization of this and other related Rickettsiales remains a major challenge, as they require a host cell for their replication. We investigated the use of an axenic medium for E. Read More

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http://dx.doi.org/10.1038/s41598-018-27574-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006305PMC
June 2018
5 Reads

A new TaqMan method for the reliable diagnosis of Ehrlichia spp. in canine whole blood.

Parasit Vectors 2018 Jun 18;11(1):350. Epub 2018 Jun 18.

ERBA Molecular, Bartholomew's Walk, Cambridgeshire Business Park, Ely, Cambridgeshire, CB7 4EA, UK.

Background: Ehrlichiosis is an important emerging infectious disease of the canid family and humans worldwide. To date, no extensive evaluation or validation of a molecular diagnostic test for ehrlichiosis has been published. Here, we present data for a newly designed TaqMan assay and compare its performance to a commercial technology (PCRun®). Read More

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http://dx.doi.org/10.1186/s13071-018-2914-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006785PMC
June 2018
6 Reads

Detection of Ehrlichia ruminantium infection in cattle in Cameroon.

BMC Res Notes 2018 Jun 14;11(1):388. Epub 2018 Jun 14.

Laboratory for Emerging Infectious Diseases, University of Buea, P. O. Box 63, Buea, Cameroon.

Objectives: Ehrlichia ruminantium infection (heartwater) is a major constraint that impacts negatively on the cattle industry development in sub-Saharan Africa and so far, little is known of the presence of heartwater in cattle in Cameroon. This study sought to investigate the prevalence of E. ruminantium infection in cattle in Cameroon and to determine the predictors of infection. Read More

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http://dx.doi.org/10.1186/s13104-018-3479-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001016PMC
June 2018
11 Reads

Investigation on Ehrlichia Infection in Small Mammals and Ticks from Tengchong, Yunnan Province, Southern China.

Vector Borne Zoonotic Dis 2018 10 13;18(10):563-566. Epub 2018 Jun 13.

2 State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology , Beijing, P.R. China .

Background: Rare investigation on tick-borne pathogens was carried out in Yunnan, China. In this study, we did a survey on Ehrlichia infection in small mammals and ticks. A total of 40 small mammals and 49 ticks were collected from Tengchong, Yunnan province. Read More

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http://dx.doi.org/10.1089/vbz.2017.2205DOI Listing
October 2018
46 Reads