3,201 results match your criteria Ehrlichiosis


Serological and molecular diagnosis of Ehrlichia canis and associated risk factors in dogs domiciled in western Cuba.

Vet Parasitol Reg Stud Reports 2018 Dec 29;14:170-175. Epub 2018 Oct 29.

Department of Epidemiology and Public Health, Veterinary Institute, Federal Rural University of Rio de Janeiro, Br 465, km 7, Seropedica, Rio de Janeiro 23897-000, Brazil. Electronic address:

Ehrlichia canis is a rickettsia transmitted by the tick, Rhipicephalus sanguineus, and is the causative agent of canine monocytic ehrlichiosis (CME). In Cuba, the first diagnosis of CME was made in 2001, but few studies have since investigated this disease locally. The objective of this study was to estimate the prevalence of E. Read More

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http://dx.doi.org/10.1016/j.vprsr.2018.10.005DOI Listing
December 2018

The rash with maculopapules and fever in adults.

Clin Dermatol 2019 Mar - Apr;37(2):109-118. Epub 2018 Dec 5.

Dermatology Department, University of CT Health Center, Farmington, Connecticut, USA. Electronic address:

There is a broad differential diagnosis for the presentation of fever and maculopapular rash in an adult. Although some causative conditions are benign, others are medical emergencies that require prompt diagnosis. We describe various conditions that result in a fever and maculopapular rash in adults. Read More

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http://dx.doi.org/10.1016/j.clindermatol.2018.12.004DOI Listing
December 2018
1 Read

Proteome Analysis Revealed Changes in Protein Expression Patterns Caused by Mutations in .

Front Cell Infect Microbiol 2019 18;9:58. Epub 2019 Mar 18.

Department of Diagnostic Medicine/Pathobiology, Center of Excellence for Vector-Borne Diseases, College of Veterinary Medicine, Kansas State University, Manhattan, KS, United States.

The tick-borne rickettsial pathogen, , causes monocytic ehrlichiosis in people and other vertebrate hosts. Mutational analysis in genome aids in better understanding of its infection and persistence in host cells and in the development of attenuated vaccines. Our recent RNA deep sequencing study revealed that three genomic mutations caused global changes in the gene expression patterns, which in turn affect the ability of pathogen's survival in a host and the host's ability to induce protection against the pathogen. Read More

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https://www.frontiersin.org/article/10.3389/fcimb.2019.00058
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http://dx.doi.org/10.3389/fcimb.2019.00058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431617PMC
March 2019
8 Reads

Molecular evidence of and and the association of infections with hematological responses in naturally infected dogs in Kalasin, Thailand.

Vet World 2019 Jan 23;12(1):131-135. Epub 2019 Jan 23.

Department of Infectious Disease Control, Faculty of Medicine, Oita University, Oita, Japan.

Background: Tick-borne bacteria, and are well recognized as the etiology of anemia and thrombocytopenia in dogs. The clinical signs of anaplasmosis and ehrlichiosis range from asymptomatic to severe symptoms . There are insufficient studies about epidemiological surveys of these blood parasites, also the association of infections with the hematological study. Read More

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http://dx.doi.org/10.14202/vetworld.2019.131-135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431820PMC
January 2019
1 Read

Lyme Neuroborreliosis - The Mystifying Pitfall: "Neuropathology and Current Therapeutics".

Recent Pat Antiinfect Drug Discov 2019 Mar 26. Epub 2019 Mar 26.

Department of Pharmacology, Institute of Pharmacy, Nirma University, Ahmadabad, Gujarat-382481. India.

Lyme's Disease (LD) is a severe rapidly growing broad spectrum chronic infection caused by the bacterium 'Borrelia (B.) burgdoferi', which can be easily transmitted through the bite of certain species of ticks. The prevalence of LD is swiftly mounting in present scenario in many countries from species to species. Read More

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http://dx.doi.org/10.2174/1574891X14666190327114641DOI Listing
March 2019
1 Read

A review on the occurrence of companion vector-borne diseases in pet animals in Latin America.

Parasit Vectors 2019 Mar 28;12(1):145. Epub 2019 Mar 28.

Institute of Parasitology, Faculty of Veterinary Medicine, Leipzig University, Leipzig, Germany.

Companion vector-borne diseases (CVBDs) are an important threat for pet life, but may also have an impact on human health, due to their often zoonotic character. The importance and awareness of CVBDs continuously increased during the last years. However, information on their occurrence is often limited in several parts of the world, which are often especially affected. Read More

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http://dx.doi.org/10.1186/s13071-019-3407-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438007PMC
March 2019
1 Read

Human ehrlichiosis at a tertiary-care academic medical center: Clinical associations and outcomes of transplant patients and patients with hemophagocytic lymphohistiocytosis.

Blood Cells Mol Dis 2019 Mar 19;77:17-22. Epub 2019 Mar 19.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.

Background: Ehrlichiosis is an acute febrile tick-borne disease which can rarely be a trigger for secondary hemophagocytic lymphohistiocytosis (HLH).

Methods: We reviewed our experience with Ehrlichia infections at a tertiary-care academic medical center.

Results: Over 10 years, 157 cases of ehrlichiosis were identified. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10799796193010
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http://dx.doi.org/10.1016/j.bcmd.2019.03.002DOI Listing
March 2019
4 Reads

Transmission of Anaplasma phagocytophilum (Foggie, 1949) by Ixodes ricinus (Linnaeus, 1758) ticks feeding on dogs and artificial membranes.

Parasit Vectors 2019 Mar 26;12(1):136. Epub 2019 Mar 26.

Bayer Animal Health GmbH, Monheim, Germany.

Background: The interplay of speed of activity of acaricidal products and tick-borne pathogen transmission time is the major driver for disease prevention. This study aimed to investigate the time required for transmission of Anaplasma phagocytophilum by adult Ixodes ricinus ticks in vivo on dogs, and to confirm the time required for transmission observed in vivo, in vitro.

Methods: Nymphs of I. Read More

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http://dx.doi.org/10.1186/s13071-019-3396-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434881PMC
March 2019
3.430 Impact Factor

An update on the treatment of canine monocytic ehrlichiosis (Ehrlichia canis).

Vet J 2019 Apr 4;246:45-53. Epub 2019 Feb 4.

Intracellular Pathogens Research Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University (NCSU-CVM),1060 William Moore Drive, Raleigh, NC 27607 USA.

Canine monocytic ehrlichiosis (CME), caused by Ehrlichia canis, a gram-negative, obligate intracellular bacterium, is a tick-borne disease of worldwide distribution. Experimentally, the course of E. canis infection can be sequentially divided into acute, subclinical and chronic phases, although distinction of these phases is challenging in the clinical setting. Read More

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http://dx.doi.org/10.1016/j.tvjl.2019.01.015DOI Listing
April 2019
1 Read

Ehrlichia spp. infection in domestic cats from Rio de Janeiro State, southeast Brazil.

Rev Bras Parasitol Vet 2019 Jan-Mar;28(1):180-185. Epub 2019 Mar 11.

Departamento de Medicina e Cirurgia Veterinária, Instituto de Veterinária, Universidade Federal Rural do Rio de Janeiro - UFRRJ, Seropédica, RJ, Brasil.

Ehrlichiosis is caused by agents belonging to Ehrlichia genus. Despite the frequent reports on the serological and molecular detection of E. canis in dogs in Brazil, there is scant data on ehrlichiosis in brazilian cats. Read More

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http://dx.doi.org/10.1590/S1984-296120180088DOI Listing
March 2019
1 Read

Seasonality and trends in incidence of human ehrlichiosis in two Missouri ecoregions.

Epidemiol Infect 2019 Jan;147:e123

Department of Statistics,Truman State University,Kirksville, MO,USA.

Ehrlichiosis is a zoonotic illness caused by Ehrlichia pathogens transmitted by ticks. Case data from 1999 to 2015, provided by the Missouri Department of Health and Senior Services (DHSS), were used to compare the seasonality and the change in incidence over time of ehrlichiosis infection in two Missouri ecoregions, Eastern Temperate Forest (ETF) and Great Plains (GP). Although the number of cases has increased over time in both ecoregions, the rate of change was significantly faster in ETF region. Read More

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https://www.cambridge.org/core/product/identifier/S095026881
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http://dx.doi.org/10.1017/S0950268818003448DOI Listing
January 2019
5 Reads

Intravascular large B-cell lymphoma: The Great Imitator.

Autops Case Rep 2018 Oct-Dec;8(4):e2018055. Epub 2018 Nov 30.

University of Vermont Medical Center, Department of Pathology and Laboratory Medicine. Burlington, Vermont, USA.

Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of diffuse large B-cell lymphoma with an estimated incidence of less than one per million. Unlike other hematopoietic malignancies, lymphadenopathy and hepatosplenomegaly are uncommon, and patients typically present with nonspecific symptoms. IVLBCL presents a diagnostic challenge and patients are usually diagnosed late in the disease course, if at all, and the prognosis is poor. Read More

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http://dx.doi.org/10.4322/acr.2018.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360824PMC
November 2018
3 Reads

Molecular characterization of Anaplasma and Ehrlichia in ixodid ticks and reservoir hosts from Palestine: a pilot survey.

Vet Med Sci 2019 Feb 14. Epub 2019 Feb 14.

Al-Quds Public Health Society, East Jerusalem, Palestine.

Tick-borne anaplasmosis and ehrlichiosis are clinically important emerging zoonoses usually overlooked by veterinarians and physicians alike. This study aimed at detecting and genetically characterizing Ehrlichia and Anaplasma species in ixodid ticks and their animal hosts from the West Bank, Palestine. A total of 723 ixodid ticks belonging to three genera (Rhipicephalus, Hyalomma, Haemaphysalis) were collected from dogs, sheep, goats and camels. Read More

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http://dx.doi.org/10.1002/vms3.150DOI Listing
February 2019

Prevalence of Borrelia burgdorferi, Anaplasma spp., Ehrlichia spp. and Dirofilaria immitis in Canadian dogs, 2008 to 2015: a repeat cross-sectional study.

Parasit Vectors 2019 Jan 28;12(1):64. Epub 2019 Jan 28.

University of Guelph, Guelph, Ontario, N1G 2W1, Canada.

Background: Vector-borne pathogens are emerging concerns in multiple regions of Canada. Determining regional prevalence of canine vector-borne pathogens and documenting change will improve clinician awareness, enable targeted prevention, enhance diagnosis and ideally reduce the risk of disease. Study objectives were to: (i) estimate the prevalence of positive canine vector-borne test results from samples submitted in Canada; (ii) assess change in prevalence over time, from baseline (2008) to 2015; and (iii) estimate the prevalence of pathogen co-infections. Read More

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https://parasitesandvectors.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13071-019-3299-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350403PMC
January 2019
10 Reads

First detection of Ehrlichia minasensis in Hyalomma marginatum ticks collected from cattle in Corsica, France.

Vet Med Sci 2019 Jan 21. Epub 2019 Jan 21.

EA7310 BIOSCOPE, Laboratoire de Virologie, Université de Corse-Inserm, Corte, France.

Ehrlichiosis are severe, feverish tick-borne illnesses caused by specific species within the genus Ehrlichia (Anaplasmataceae family). Recent data suggest that ruminants in Corsica area reservoir for several Anaplasmataceae species. The purpose of our study was to determine whether Ehrlichia species could be detected in ticks collected in Corsican ruminants by using molecular methods. Read More

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http://dx.doi.org/10.1002/vms3.140DOI Listing
January 2019

PCR detection of Ehrlichia ruminantium and Babesia bigemina in cattle from Kwara State, Nigeria: unexpected absence of infection.

Parasitol Res 2019 Mar 17;118(3):1025-1029. Epub 2019 Jan 17.

Bristol Veterinary School, University of Bristol, Langford, Bristol, BS40 5DU, UK.

Ticks and tick-borne diseases (TBDs) continue to pose an insidious and ever-present threat to livestock and livelihoods across the globe. Two of the most significant TBDs of cattle in Africa are heartwater and babesioisis, caused by Ehrlichia ruminantium and Babesia bigemina respectively. Both pathogens are endemic in Nigeria. Read More

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http://dx.doi.org/10.1007/s00436-019-06204-1DOI Listing
March 2019
2 Reads
2.327 Impact Factor

Molecular detection and characterization of Ehrlichia ruminantium from cattle in Mozambique.

Acta Trop 2019 Mar 9;191:198-203. Epub 2019 Jan 9.

Laboratório de Imunoparasitologia, Departamento de Patologia Veterinária, Faculdade de Ciências Agrárias e Veterinárias (FCAV), Universidade Estadual Paulista (Unesp), Jaboticabal, SP, Brazil. Electronic address:

Heartwater caused by Ehrlichia ruminantiumis a disease of domestic and wild ruminants and one of the most economically important tick-borne diseases in Africa. The present study aimed to investigate the occurrence and genetic diversity of E. ruminantium in blood samples from 210 cattle sampled in five districts of Maputo Province, Mozambique. Read More

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http://dx.doi.org/10.1016/j.actatropica.2019.01.007DOI Listing
March 2019
2 Reads

Molecular characterization of Ehrlichia canis from naturally infected dogs from the state of Rio de Janeiro.

Braz J Microbiol 2019 Jan 11;50(1):1-12. Epub 2018 Dec 11.

Department of Animal Parasitology, Veterinary Institute, Federal Rural University of Rio de Janeiro, BR 465, km 7, Seropédica, Rio de Janeiro, 23890-000, Brazil.

The aim of the present study was to evaluate the genetic diversity of Ehrlichia canis in naturally infected dogs from six mesoregions of Rio de Janeiro state. E. canis was diagnosed with a real-time polymerase chain reaction (qPCR) targeting a 93 base pair (bp) fragment of the 16S rDNA gene. Read More

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http://dx.doi.org/10.1007/s42770-018-0020-7DOI Listing
January 2019
16 Reads

Molecular Detection and Phylogenetic Analysis of Anaplasma phagocytophilum in Horses in Korea.

Korean J Parasitol 2018 Dec 31;56(6):559-565. Epub 2018 Dec 31.

College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Korea.

The identification and characterization of pathogenic and zoonotic tick-borne diseases like granulocytic anaplasmosis are essential for developing effective control programs. The differential diagnosis of pathogenic Anaplasma phagocytophilum and non-pathogenic A. phagocytophilum-like Anaplasma spp. Read More

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http://parasitol.kr/journal/view.php?doi=10.3347/kjp.2018.56
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http://dx.doi.org/10.3347/kjp.2018.56.6.559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327205PMC
December 2018
9 Reads

Molecular identification of Ehrlichia ewingii in a polyarthritic Texas dog.

Vet Clin Pathol 2019 Mar 9;48(1):96-99. Epub 2019 Jan 9.

Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, College Station, Texas.

An 8-year-old, neutered male, Golden Retriever presented for bilateral carpal joint effusion. A complete blood count revealed mild leukopenia and marked thrombocytopenia. Samples were sent to the Texas A&M Veterinary Medical Diagnostic Laboratory for blood smear review and serologic testing for tick-borne diseases. Read More

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http://doi.wiley.com/10.1111/vcp.12690
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http://dx.doi.org/10.1111/vcp.12690DOI Listing
March 2019
19 Reads

Evidence of in Argentina through molecular detection in marsh deer ().

Int J Parasitol Parasites Wildl 2019 Apr 17;8:45-49. Epub 2018 Dec 17.

Instituto de Biotecnología, Instituto Nacional de Tecnología Agropecuaria (INTA), Las Cabañas y Los Reseros s/n (B1712WAA), Castelar, Buenos Aires, Argentina.

Vector-borne pathogens are responsible for serious emerging diseases and have been widely described in wildlife. causes the zoonotic "monocytic ehrlichiosis" in humans, is transmitted by the tick and its reservoir host is the white-tailed deer () in North America. Little is known about the native reservoir and the tick vectors involved in the transmission cycle in South America. Read More

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http://dx.doi.org/10.1016/j.ijppaw.2018.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312859PMC
April 2019
1 Read

Low genetic diversity of Ehrlichia canis associated with high co-infection rates in Rhipicephalus sanguineus (s.l.).

Parasit Vectors 2019 Jan 7;12(1):12. Epub 2019 Jan 7.

UMR BIPAR, INRA, ANSES, Ecole Nationale Vétérinaire d'Alfort, Université Paris-Est, 94700, Maisons-Alfort, France.

Background: Rhipicephalus sanguineus sensu lato (s.l.) is the most widely distributed ixodid tick and is a vector of major canine and human pathogens. Read More

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https://parasitesandvectors.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13071-018-3194-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322249PMC
January 2019
19 Reads
3.430 Impact Factor

Clinicopathological findings in 41 dogs (2008-2018) naturally infected with Ehrlichia ewingii.

J Vet Intern Med 2019 Mar 2;33(2):618-629. Epub 2019 Jan 2.

Vector Borne Disease Diagnostic Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina.

Background: Ehrlichia ewingii is the most seroprevalent Ehrlichia-infecting dogs in the southern and mid-western United States. Fever, lameness, and polyarthritis are commonly reported findings in dogs naturally infected with E. ewingii. Read More

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http://dx.doi.org/10.1111/jvim.15354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430920PMC
March 2019
3 Reads

Ehrlichia ruminantium antigens and peptides induce cytotoxic T cell responses in vitro.

Vet Immunol Immunopathol 2019 Jan 19;207:1-9. Epub 2018 Nov 19.

Agricultural Research Council-Onderstepoort Veterinary Research, Private Bag X5, Onderstepoort 0110, South Africa; Department of Veterinary Tropical Diseases, Veterinary Faculty, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa.

Since CD8 T cells play an important role in resistance to infection with heartwater, effective vaccines against this disease will likely require identification of antigens that contain CD8 T cell epitopes responsible for cytotoxic T lymphocyte (CTL) responses. With the use of the fluorescent antigen-transfected target cell (FATT)-CTL assay, IFN-γ ELISPOT and flow cytometry, peptides that induce CTL, proliferation of CD8 + T cells and IFN-γ production were identified as possible target antigens for vaccine development. Of particular relevance was the finding that different peptides from different antigens were able to elicit varied cytotoxic activities by immune peripheral blood mononuclear cells (PBMC) from heartwater immune tick-infected sheep. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01652427183029
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http://dx.doi.org/10.1016/j.vetimm.2018.11.012DOI Listing
January 2019
15 Reads

Prevalence of Ehrlichia canis (Rickettsiales: Ehrlichieae) DNA in Tissues From Rhipicephalus sanguineus (Acari: Ixodidae) Ticks in Areas Endemic for Canine Monocytic Ehrlichiosis in Brazil.

J Med Entomol 2019 Apr;56(3):828-831

Universidade Estadual Paulista (Unesp), Faculdade de Medicina Veterinária de Araçatuba, Dona Amélia, Araçatuba, Brazil.

Canine monocytic ehrlichiosis (CME) is a disease caused by the obligate intracellular bacterium Ehrlichia canis. Tropical lineages of Rhipicephalus sanguineus ticks play an essential role in the transmission of this pathogen. The aim of the present study was to evaluate the prevalence of E. Read More

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http://dx.doi.org/10.1093/jme/tjy220DOI Listing

Molecular detection of rickettsial tick-borne agents in white-tailed deer (Odocoileus virginianus yucatanensis), mazama deer (Mazama temama), and the ticks they host in Yucatan, Mexico.

Ticks Tick Borne Dis 2019 02 27;10(2):365-370. Epub 2018 Nov 27.

Campus de Ciencias Biológicas y Agropecuarias, Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Yucatán, Yucatán, Mexico.

Twenty-five white-tailed deer (Odocoileus virginianus yucatanensis) (WTD), 4 mazama deer (Mazama temama) (MD), and the ticks they host in Yucatan, Mexico were sampled to run a molecular survey for tick-borne rickettsial agents. The prevalence of rickettsial agents was 20% in WTD (5/25) and 50% in MD (2/4). When sequencing the nested PCR products, E. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2018.11.018DOI Listing
February 2019
1 Read

Comparative Evaluation of 2 In-Clinic Assays for Vector-Borne Disease Testing in Dogs.

Top Companion Anim Med 2018 Dec 13;33(4):114-118. Epub 2018 Sep 13.

Assay R&D, IDEXX Laboratories Inc, Westbrook, ME, USA. Electronic address:

Vector-borne agents comprise medically important infections affecting dogs throughout much of the world. Sensitive detection of antibodies directed at tick-borne disease-causing organisms in dogs is diagnostically important for veterinarians, pets and their owners, and epidemiologically important for public health surveillance. The SNAP 4Dx Plus Test (IDEXX Laboratories, Inc. Read More

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http://dx.doi.org/10.1053/j.tcam.2018.09.003DOI Listing
December 2018
6 Reads

Isolation and molecular detection of Ehrlichia species from ticks in western, central, and eastern Japan.

Ticks Tick Borne Dis 2019 02 13;10(2):344-351. Epub 2018 Nov 13.

United Graduate School of Agricultural Science and Veterinary Science, Gifu University, Gifu, Japan; Department of Virology 1, National Institute of Infectious Diseases, Tokyo, Japan.

Ehrlichiosis is a tick-borne bacterial disease caused by pathogens of the Ehrlichia genus. Although human ehrlichiosis has not been reported in Japan, Ehrlichia spp., which are closely related to Ehrlichia chaffeensis, were detected in several species of ixodid ticks. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2018.11.010DOI Listing
February 2019
1 Read

PCR sensitivity of peripheral blood of dogs co-infected with Leishmania spp. and Ehrlichia spp. in endemic area of Brazil.

Rev Soc Bras Med Trop 2018 Nov-Dec;51(6):843-847

Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal da Grande Dourados , Dourados, MS, Brasil.

Introduction: Peripheral blood of 400 dogs infected with Leishmania and Ehrlichia were analyzed using polymerase chain reaction (PCR), and clinical signs were characterized.

Methods: PCR and parasitological tests were conducted.

Results: PCR was positive for Leishmania in 84. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
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http://dx.doi.org/10.1590/0037-8682-0040-2018DOI Listing
February 2019
13 Reads

Repeated cross-sectional study of Trypanosoma cruzi in shelter dogs in Texas, in the context of Dirofilaria immitis and tick-borne pathogen prevalence.

J Vet Intern Med 2019 Jan 29;33(1):158-166. Epub 2018 Nov 29.

Department of Veterinary Integrative Biosciences, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, Texas.

Background: Vector-borne diseases have an adverse impact on health of dogs, and infected dogs can be sentinels for human infection. Infection with Trypanosoma cruzi, an agent of Chagas disease, causes fatal heart disease in dogs across the southern United States but has been neglected from wide-scale prevalence studies.

Objectives: To determine the prevalence of exposure to T. Read More

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http://dx.doi.org/10.1111/jvim.15352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335532PMC
January 2019
21 Reads

Occupational risk for personnel working in veterinary clinics through exposure to vectors of rickettsial pathogens.

Ticks Tick Borne Dis 2019 02 31;10(2):299-304. Epub 2018 Oct 31.

Universidad Autónoma de Cd. Juárez (UACJ), Av. Plutarco Elias Calles 1210, Cd. Juárez, Chihuahua, 32310, Mexico. Electronic address:

Workers at veterinary clinics are exposed to zoonotic pathogens, which, though infrequently, can lead to serious consequences. The aim of the present study was to estimate the seroprevalence for rickettsial pathogens in veterinary clinic personnel in Ciudad Juárez, Chihuahua, Mexico. Voluntary participants included 106 veterinarians, 19 pet groomers, 36 veterinary assistants and 6 administrative workers who supplied blood samples taken by venipuncture. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2018.10.012DOI Listing
February 2019
14 Reads

Risk factors associated with the carriage of Ixodes scapularis relative to other tick species in a population of pet dogs from southeastern Ontario, Canada.

Ticks Tick Borne Dis 2019 02 17;10(2):290-298. Epub 2018 Oct 17.

Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario, NIG 2WI, Canada; Canadian Wildlife Health Cooperative, Ontario Veterinary College, University of Guelph, Guelph, Ontario, NIG 2WI, Canada. Electronic address:

In eastern North America, the blacklegged tick, Ixodes scapularis, is the vector for Borrelia burgdorferi sensu stricto and Anaplasma phagocytophilum, the causal agents for human and canine Lyme disease and anaplasmosis, respectively. The extensive range expansion of I. scapularis in Ontario is a growing veterinary and public health concern. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2018.10.004DOI Listing
February 2019
7 Reads

Role of mustelids in the life-cycle of ixodid ticks and transmission cycles of four tick-borne pathogens.

Parasit Vectors 2018 Nov 20;11(1):600. Epub 2018 Nov 20.

Centre for Zoonoses and Environmental Microbiology, Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.

Background: Elucidating which wildlife species significantly contribute to the maintenance of Ixodes ricinus populations and the enzootic cycles of the pathogens they transmit is imperative in understanding the driving forces behind the emergence of tick-borne diseases. Here, we aimed to quantify the relative contribution of four mustelid species in the life-cycles of I. ricinus and Borrelia burgdorferi (sensu lato) in forested areas and to investigate their role in the transmission of other tick-borne pathogens. Read More

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http://dx.doi.org/10.1186/s13071-018-3126-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245527PMC
November 2018
3 Reads

Investigation of the tick-borne pathogens Rickettsia helvetica and Anaplasma phagocytophilum in the blood of the domestic goat (Capra hircus).

Authors:
A Rymaszewska

Pol J Vet Sci 2018 Jun;21(2):415-417

Department of Genetics, University of Szczecin, Felczaka 3C, 71-412 Szczecin, Poland.

The bacterial species Anaplasma phagocytophilum and Rickettsia helvetica are pathogenic for humans and domestic animals and are transmitted by ticks, e.g., of the Ixodes genus. Read More

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http://dx.doi.org/10.24425/122607DOI Listing
June 2018
1 Read

Ehrlichiosis presenting as severe sepsis and meningoencephalitis in an immunocompetent adult.

JMM Case Rep 2018 Sep 27;5(9):e005162. Epub 2018 Jul 27.

Department of Pharmacy Practice and Science, University of Kentucky College of Pharmacy, Lexington, KY, USA.

Introduction: are obligate intracellular pathogens transmitted to vertebrates by ticks.

Case Presentation: We report the case of a 59-year-old man who presented to the University of Kentucky Albert B. Chandler Medical Center (Lexington, KY, USA) after being found fallen down in the woods. Read More

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http://dx.doi.org/10.1099/jmmcr.0.005162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230758PMC
September 2018
5 Reads

Seroprevalence and current infections of canine vector-borne diseases in Nicaragua.

Parasit Vectors 2018 Nov 12;11(1):585. Epub 2018 Nov 12.

Institute for Parasitology, Centre for Infection Medicine, University of Veterinary Medicine Hannover, Buenteweg 17, 30559, Hannover, Germany.

Background: Vector-borne diseases constitute a major problem for veterinary and public health, especially in tropical regions like Central America. Domestic dogs may be infected with several vector-borne pathogens of zoonotic relevance, which may also severely compromise canine health.

Methods: To assess the prevalence of canine vector-borne diseases in Nicaragua, 329 dogs from seven cities, which were presented to the veterinarian for various reasons, were included in this study. Read More

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https://parasitesandvectors.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13071-018-3173-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233566PMC
November 2018
15 Reads

Survey and Phylogenetic Analysis of Rodents and Important Rodent-Borne Zoonotic Pathogens in Gedu, Bhutan.

Korean J Parasitol 2018 Oct 31;56(5):521-525. Epub 2018 Oct 31.

International Development Group, School of Veterinary Science, Massey University, Palmerston North, New Zealand.

Rodents are well-known reservoirs and vectors of many emerging and re-emerging infectious diseases, but little is known about their role in zoonotic disease transmission in Bhutan. In this study, a cross-sectional investigation of zoonotic disease pathogens in rodents was performed in Chukha district, Bhutan, where a high incidence of scrub typhus and cases of acute undifferentiated febrile illness had been reported in people during the preceding 4-6 months. Twelve rodents were trapped alive using wire-mesh traps. Read More

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http://parasitol.kr/journal/view.php?doi=10.3347/kjp.2018.56
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http://dx.doi.org/10.3347/kjp.2018.56.5.521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243181PMC
October 2018
21 Reads

The relationship between ehrlichiosis and the development of hematologic malignancies.

Med Hypotheses 2018 Dec 14;121:57-59. Epub 2018 Sep 14.

Rush University Medical Center, Division of Hematology/Oncology and Cell Therapy, 1725 W. Harrison, Suite 809, Chicago, IL 60612, United States. Electronic address:

Viral and bacterial infections cause chronic inflammation and produce bacterial metabolites that may lead to carcinogenesis. Ehrlichiosis is an intracellular infection that primarily infects white blood cells. Given that infections can lead to cancer, and that Ehrlichia has tropism for white blood cells, it can be deduced that Ehrlichia may cause hematologic malignancies, such as acute leukemia. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03069877183047
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http://dx.doi.org/10.1016/j.mehy.2018.09.026DOI Listing
December 2018
13 Reads

Seroprevalence of vector-borne pathogens in dogs from Croatia.

Parasitol Res 2019 Jan 31;118(1):347-352. Epub 2018 Oct 31.

Department for Bacteriology and Parasitology, Croatian Veterinary Institute, Zagreb, Savska cesta 143, 10000, Zagreb, Croatia.

Canine vector-borne pathogens (VBPs) are a group of globally distributed and rapidly spreading microorganisms transmitted by arthropods. In the present survey, we investigated Anaplasma spp., Ehrlichia canis, Dirofilaria immitis and Borrelia burgdorferi sensu lato seroprevalence between three groups of dogs (asymptomatic, suspected and deceased) from continental and coastal regions of Croatia with the commercial point-of-care SNAP®4Dx®Plus for VBPs. Read More

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http://link.springer.com/10.1007/s00436-018-6129-7
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http://dx.doi.org/10.1007/s00436-018-6129-7DOI Listing
January 2019
4 Reads

Current Status of Tick-Borne Diseases in South Korea.

Vector Borne Zoonotic Dis 2019 Apr 17;19(4):225-233. Epub 2018 Oct 17.

1 Department of Internal Medicine and Inha University School of Medicine, Incheon, Republic of Korea.

Background: Bites with tick-borne pathogens can cause various bacterial, viral, or parasitic diseases in humans. Tick-transmitted diseases are known as contributing factors to the increasing incidence and burden of diseases. The present article investigated the epidemiology of tick-borne diseases in South Korea. Read More

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http://dx.doi.org/10.1089/vbz.2018.2298DOI Listing
April 2019
10 Reads

Prevalence of canine Babesia and Ehrlichia co-infection and the predictive value of haematology.

Onderstepoort J Vet Res 2018 Oct 9;85(1):e1-e5. Epub 2018 Oct 9.

Department of Companion Animal Clinical Studies, University of Pretoria.

Canine babesiosis and ehrlichiosis are important tick-borne infections in South Africa. Many South African general veterinary practitioners perceive co-infection with Ehrlichia spp. as a common occurrence in dogs with babesiosis. Read More

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http://dx.doi.org/10.4102/ojvr.v85i1.1626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324083PMC
October 2018
5 Reads

Epidemiology of Ehrlichia canis in healthy dogs from the Southeastern region of the state of Rio de Janeiro, Brazil.

Prev Vet Med 2018 Nov 14;159:135-142. Epub 2018 Sep 14.

Department of Epidemiology and Public Health, Veterinary Institute, Federal Rural University of Rio de Janeiro, Br 465, km 7, Seropedica, Rio de Janeiro, 23897-000, Brazil. Electronic address:

This cross-sectional, observational, and descriptive study aims to investigate the epidemiology of Ehrlichia canis in healthy owned dogs from the Southeastern region of Rio de Janeiro, Brazil. Blood samples were collected from 390 households dogs. During the visits, an epidemiological questionnaire was filled out concerning the dogs' characteristics as well as the environments in which they lived. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01675877183032
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http://dx.doi.org/10.1016/j.prevetmed.2018.09.012DOI Listing
November 2018
13 Reads

Ehrlichiosis masquerading as thrombotic thrombocytopenic purpura.

BMJ Case Rep 2018 Oct 2;2018. Epub 2018 Oct 2.

Department of Pulmonary and Critical Care Medicine, University of Louisville, Louisville, Kentucky, USA.

Ehrlichiosis is a rare tickborne illness that can manifest from an asymptomatic, self-limiting disease to a severe presentation with encephalopathy and renal failure. Ehrlichiosis is diagnosed largely based on patient history with confirmatory tests including peripheral blood smear, serology and PCR. Empiric treatment is warranted in patients with suspected tick bites as a delay in treatment can result in multiorgan failure. Read More

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http://dx.doi.org/10.1136/bcr-2018-226665DOI Listing
October 2018
9 Reads

Development and Clinical Validation of a Multiplex Real-Time Quantitative PCR Assay for Human Infection by Anaplasma phagocytophilum and Ehrlichia chaffeensis.

Trop Med Infect Dis 2018 Jan 29;3(1). Epub 2018 Jan 29.

Joint Departments of Pathology, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Walter Reed National Military Medical Center, Joint Pathology Center, Bethesda, MD 20814, USA.

Background: Human granulocytic anaplasmosis (HGA), caused by , and human monocytic ehrlichiosis (HME), caused by , often present as undifferentiated fever but are not treated by typical empiric regimens for acute febrile illness. Their role as agents of vector-borne febrile disease in tropical regions is more poorly studied than for other rickettsial infections. Limitations in diagnosis have impaired epidemiologic and clinical research and needless morbidity and mortality occur due to untreated illness. Read More

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http://www.mdpi.com/2414-6366/3/1/14
Publisher Site
http://dx.doi.org/10.3390/tropicalmed3010014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136628PMC
January 2018
7 Reads

Large-scale health disparities associated with Lyme disease and human monocytic ehrlichiosis in the United States, 2007-2013.

PLoS One 2018 27;13(9):e0204609. Epub 2018 Sep 27.

Department of Ecology and Evolutionary Biology, University of Colorado, Boulder, Colorado, United States of America.

Promoting health equity is a fundamental public health objective, yet health disparities remain largely overlooked in studies of vectorborne diseases, especially those transmitted by ticks. We sought to identify health disparities associated with Lyme disease and human monocytic ehrlichiosis, two of the most pervasive tickborne diseases within the United States. We used general linear mixed models to measure associations between county-level disease incidence and six variables representing racial/ethnic and socioeconomic characteristics of counties (percent white non-Hispanic; percent with a bachelors degree or higher; percent living below the poverty line; percent unemployed; percent of housing units vacant; per capita number of property crimes). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0204609PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160131PMC
March 2019
2 Reads

Continued expansion of tick-borne pathogens: Tick-borne encephalitis virus complex and Anaplasma phagocytophilum in Denmark.

Ticks Tick Borne Dis 2019 01 17;10(1):115-123. Epub 2018 Sep 17.

Clinical Centre for Emerging and Vector-borne Infections, Odense University Hospital, Sdr. Boulevard 29, DK-5000, Odense C, Denmark; Department of Infectious diseases, Odense University Hospital, Sdr. Boulevard 29, DK-5000, Odense C, Denmark. Electronic address:

Tick-borne encephalitis virus (TBEV) is a tick-transmitted flavivirus within the tick-borne encephalitis (TBE) complex. The TBE complex is represented by both TBEV and louping ill virus (LIV) in Denmark. Anaplasma phagocytophilum is also transmitted by ticks and is believed to play an essential role in facilitating and aggravating LIV infection in sheep. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2018.09.007DOI Listing
January 2019

Prevalence of Canine Monocytic Ehrlichiosis in Canine Population Across India.

Arch Razi Inst 2018 Jun 1;73(2):87-93. Epub 2018 Mar 1.

Biotechnology Section, Central Military Veterinary Laboratory, remount Veterinary Corps, Meerut Cantt, Uttar Pradesh, 250001, India.

Canine ehrlichiosis is a very important emerging disease in India. This study is the first attempt screening a large number of canines in India for the detection of canine monocytic ehrlichiosis. In the present study, 510 blood samples of dogs were screened for the presence of Ehrlichia canis and other variants of Anaplasmataceae family by serological and molecular methods. Read More

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http://archrazi.areeo.ac.ir/article_116616.html
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http://dx.doi.org/10.22092/ari.2018.116616DOI Listing
June 2018
1 Read

Exposure to Ticks and their Pathogens in Northeast Missouri.

Authors:
Deborah A Hudman

Mo Med 2018 Jul-Aug;115(4):374-379

Deborah A. Hudman, MS, is in the Department of Microbiology/Immunology, A.T. Still University Kirksville College of Osteopathic Medicine.

While the prevalence of human pathogens has been quantified in ticks in Adair County, Missouri, the prevalence of residents acquiring tick-borne diseases and seeking medical treatment has not. A public survey (n=109) revealed that 96% of respondents reported finding attached ticks on their person; of these, 38% developed symptoms post tick bite; of these, 55% reported consultation with a health care provider. Overall, 89% of practitioners surveyed had treated at least one patient for tick-borne disease. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140261PMC
September 2018
6 Reads

Successful Infection of Tick Cell Cultures of Rhipicephalus sanguineus (Tropical Lineage) with Ehrlichia canis.

Vector Borne Zoonotic Dis 2018 Sep 17. Epub 2018 Sep 17.

6 Federal University of Uberlândia , Uberlândia, Brazil .

There are two distinct lineages of ticks, Rhipicephalus sanguineus, in South America: tropical and temperate lineages. Only the tropical lineage is recognized as competent vector for Ehrlichia canis. The epidemiological data of canine monocytic ehrlichiosis is congruent with the distribution of the two lineages of R. Read More

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http://dx.doi.org/10.1089/vbz.2017.2197DOI Listing
September 2018

Identification of novel immunoreactive proteins and delineation of a specific epitope of Anaplasma phagocytophilum.

Microb Pathog 2018 Dec 11;125:183-188. Epub 2018 Sep 11.

Department of Microbiology, College of Medicine, Soochow University, Suzhou, Jiangsu Province, 215123, China. Electronic address:

Human granulocytic anaplasmosis (HGA), an increasingly recognized febrile tick-borne illness, is caused by a gram-negative obligate intracellular bacterium Anaplasma phagocytophilum. Because of nonspecific clinical manifestations, diagnosis of HGA highly depends on laboratory tests. Identification of immunoreactive proteins is prerequisite for development of specific and sensitive immunoassays for HGA. Read More

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http://dx.doi.org/10.1016/j.micpath.2018.09.017DOI Listing
December 2018
2 Reads
2.000 Impact Factor