Dermatol Online J 2018 Feb 15;24(2). Epub 2018 Feb 15.
Department of Medicine, Division of Dermatology, David Geffen School of Medicine at UCLA, Los Angeles, California.
The term, autosomal recessive congenital ichthyosis (ARCI), describes a group of rare genetic skin diseases of cornification involving hyperkeratotic scaling at birth. The defective skin barrier function may lead to dehydration, body temperature instability, and high susceptibility to infections. In most cases of ARCI, neonates are born with a collodion membrane covering the body, often presenting with ectropion and eclabium. Read More