Arch Virol 2021 Apr 8;166(4):1231-1236. Epub 2021 Feb 8.
Department of Pediatric Intensive Care Unit (PICU), The Affiliated Wuxi Children's Hospital of Nanjing Medical University, Wuxi, 214023, China.
The species Enterovirus B includes diverse serotypes that can cause a wide spectrum of human diseases, such as aseptic encephalitis, myocarditis, and paralysis. In this study, a 4-year-old child was diagnosed with viral encephalitis, but the causative agent could not be identified using routine immunological tests. Using metagenomic RNA sequencing, a novel strain of enterovirus B, strain PC06, was identified, and its genome sequence was determined by RT-PCR and Sanger sequencing. Read More