19,738 results match your criteria Echinococcosis Hydatid Cyst


Surgery for parasitic lung infestations: roles in diagnosis and treatment.

J Thorac Dis 2018 Oct;10(Suppl 28):S3446-S3457

Manmohan Cardiothoracic Vascular and Transplant Centre, Kathmandu, Nepal.

Pulmonary parasitic infestations are a worldwide problem associated with significant morbidity and socioeconomic impact. They are known to have varied clinical presentations and radiological appearances. Prevention of parasite transmission and medical treatment of cases form the two pillars of control of these diseases. Read More

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October 2018

Oxfendazole: a promising agent for the treatment and control of helminth infections in humans.

Expert Rev Anti Infect Ther 2018 Dec 1. Epub 2018 Dec 1.

e Johns Hopkins Bloomberg School of Public Health , 615 N. Wolfe Street, Baltimore , MD 21205 , USA.

Introduction: Oxfendazole (methyl [5-(phenylsulphinyl)-1H benzimidazole- 2-yl] carbamate) has a particularly long metabolic half-life in ruminants, and its metabolite fenbendazole also has anthelminthic action. A very limited number of drugs are available for the treatment of some zoonotic helminth infections, such as neurocysticercosis and echinococcosis. More recent work has expanded oxfendazole's non-clinical safety profile and demonstrated its safety and bioavailability in healthy human volunteers, thus advancing the possibility of a new and greatly needed option for antiparasitic treatment of geohelminths and tissue parasites. Read More

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December 2018

Recombinant α- and β-tubulin from Echinococcus granulosus: expression, purification and polymerization.

Parasite 2018 5;25:62. Epub 2018 Dec 5.

National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory of Parasite and Vector Biology, MOH, National Center for International Research on Tropical Diseases, WHO Collaborating Centre for Tropical Diseases, Shanghai 200025, People's Republic of China.

Echinococcosis, which causes a high disease burden and is of great public health significance, is caused by the larval stage of Echinococcus species. It has been suggested that tubulin is the target of benzimidazoles, the only drugs for the treatment of echinococcosis. This study evaluated the characteristics of tubulins from Echinococcus granulosus. Read More

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December 2018

Cystic echinococcosis in the thigh: a case report.

Infection 2018 Dec 3. Epub 2018 Dec 3.

Department of Internal Medicine II, Innsbruck Medical University, Anichstraße 35, 6020, Innsbruck, Austria.

Intramuscular cystic echinococcosis is a very rare occurrence. Herein we report a case of a 37-year-old patient who presented with progressive swelling of his left thigh. Ultrasound evaluation showed a multicystic, encapsulated lesion (16 × 3. Read More

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December 2018

The ectodomains of the lymphocyte scavenger receptors CD5 and CD6 interact with tegumental antigens from Echinococcus granulosus sensu lato and protect mice against secondary cystic echinococcosis.

PLoS Negl Trop Dis 2018 Nov 30;12(11):e0006891. Epub 2018 Nov 30.

Immunoreceptors del Sistema Innat i Adaptatiu, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

Background: Scavenger Receptors (SRs) from the host's innate immune system are known to bind multiple ligands to promote the removal of non-self or altered-self targets. CD5 and CD6 are two highly homologous class I SRs mainly expressed on all T cells and the B1a cell subset, and involved in the fine tuning of activation and differentiation signals delivered by the antigen-specific receptors (TCR and BCR, respectively), to which they physically associate. Additionally, CD5 and CD6 have been shown to interact with and sense the presence of conserved pathogen-associated structures from bacteria, fungi and/or viruses. Read More

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November 2018

Role of microRNAs in host defense against Echinococcus granulosus infection: a preliminary assessment.

Immunol Res 2018 Nov 29. Epub 2018 Nov 29.

Unit of Infectious and Tropical Diseases, San Matteo Hospital Foundation, Pavia, Italy.

Cystic echinococcosis (CE) is a neglected helminthic zoonosis caused by the larval stage of the tapeworm Echinococcus granulosus s.l. MicroRNAs (miRNAs) are regulators of gene expression that have been linked with the pathogenesis of several human diseases, but little exists in the available literature about miRNAs in CE. Read More

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November 2018

Ex Vivo Liver Resection and Autotransplantation versus Allotransplantation for End-stage Hepatic Alveolar Echinococcosis.

Int J Infect Dis 2018 Nov 26. Epub 2018 Nov 26.

Department of Liver Surgery, Liver Transplantation Center, West China Hospital of Sichuan University, Chengdu, Sichuan Province, China. Electronic address:

Objective: To compare the clinical outcomes of ex vivo liver resection and autotransplantation (ERAT) with allotransplantation in end-stage hepatic alveolar echinococcosis (HAE) patients.

Methods: From January 2008 to October 2017, 41 of 254 patients with end-stage HAE fulfilled the inclusion criteria (group ERAT, n=35 versus group allotransplantation, n=6). Each group was assessed for indications and short- and long-term outcomes. Read More

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November 2018

Right ventricular hydatid cyst presented as tachyarrhythmia.

Asian Cardiovasc Thorac Ann 2018 Nov 28:218492318817665. Epub 2018 Nov 28.

Department of Cardiovascular and Thoracic Surgery, King George's Medical University, Lucknow, Uttar Pradesh, India.

Cardiac hydatidosis is a rare presentation of echinococcus granulosus infestation. We report the case of 57-year-old man who presented with syncope due to ventricular tachycardia and was managed with antiarrhythmic drugs for an acute episode. Echocardiography and cardiac magnetic resonance imaging suggested a 1 cm right ventricular hydatid cyst. Read More

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November 2018
4 Reads

Oxidant/Antioxidant Status, PON1 and ARES Activities, Trace Element Levels, and Histological Alterations in Sheep with Cystic Echinococcosis.

Iran J Parasitol 2018 Jul-Sep;13(3):448-456

Dept. of Biochemistry, Faculty of Veterinary Medicine, University of Siirt, Siirt, Turkey.

Background: Total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI), nitric oxide (NO), zinc (Zn), copper (Cu) levels, paraoxonase (PON1), arylesterase (ARES) activities, and biochemical changes were studied on sheep with cystic echinococcosis.

Methods: The materials were taken from 2-3 yr old sheep slaughtered in Van Province, Turkey in 2017. Before the slaughter, blood samples were collected from the healthy sheep, while various organs of animals were examined for hydatid cysts after the slaughter. Read More

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November 2018

Genetic Identification of Isolates in Hamadan, Western Iran.

Iran J Parasitol 2018 Jul-Sep;13(3):423-429

Dept. of Medical Parasitology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.

Background: Cystic echinococcosis is a zoonotic infection and considered as a major economic and public health concern worldwide. This research was conducted to determine genotypic characteristics of livestock and human hydatid cyst isolates from Hamadan area, western Iran.

Methods: Sampling was conducted in Hamadan industrial slaughterhouse and Beast Hospital of Hamadan City, western Iran, from 2015 to 2016. Read More

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November 2018

Echinococcus granulosus sensu stricto: silencing of thioredoxin peroxidase impairs the differentiation of protoscoleces into metacestodes.

Parasite 2018 26;25:57. Epub 2018 Nov 26.

State Key Laboratory of Pathogenesis, Prevention, Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830054, PR China - Branch of The First Affiliated Hospital of Xinjiang Medical University, Changji, Xinjiang 831100, PR China.

Cystic echinococcosis (CE) is a cosmopolitan parasitic disease caused by infection with the larval stage of Echinococcus granulosus sensu lato. Thioredoxin peroxidase (TPx) may play an essential role in the antioxidant defence system of E. granulosus s. Read More

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November 2018
1 Read
0.822 Impact Factor

Never seen before? Opisthorchiasis and Clonorchiasis.

Z Gastroenterol 2018 Nov 22. Epub 2018 Nov 22.

Department of Ultrasound, Zhongshan Hospital, Fudan University, 200032 Shanghai, China.

Parasitic diseases are relatively rarely diagnosed and treated in Europe. Therefore, European clinicians are not familiar with their clinical and imaging features. In an era of increased human migration, it is fundamental for clinicians to be able to identify such diseases. Read More

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November 2018
5 Reads

Seroepidemiological study of cystic echinococcosis in nomadic communities in the southwest of Iran: A population-based study.

J Immunoassay Immunochem 2018 Nov 21:1-10. Epub 2018 Nov 21.

a Cellular and Molecular Research Center , Yasuj University of Medical Sciences , Yasuj , Iran.

The current study aimed at the seroepidemiological survey of human cystic echinococcosis (CE) in nomadic people in Boyer-Ahmad District in the southwest of Iran. One thousand and five nomads were selected by cross-sectional sample collection in nomadic tribes of Boyer-Ahmad District in the southwest of Iran. Blood samples were taken from each individual, and the sera were tested for detection of anti-hydatid cyst antibodies using antigen B-ELISA. Read More

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November 2018
3 Reads

Lateral flow dipstick antigen assay for human cystic echinococcosis.

Acta Trop 2018 Nov 17;190:171-176. Epub 2018 Nov 17.

Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Penang, Malaysia. Electronic address:

Cystic echinococcosis (CE) is a neglected zoonotic disease with a worldwide distribution and is a major public health problem in some areas. Diagnosis of CE is mainly based on clinical symptoms, imaging and serological testing, however, improvement in serodiagnosis is still needed. This study was aimed at detecting circulating Echinococcus antigen in CE patients using a lateral flow dipstick (LFD) assay. Read More

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November 2018
3 Reads

Genetic Diversity in From the Plateau Vole and Plateau Pika in Jiuzhi County, Qinghai Province, China.

Front Microbiol 2018 5;9:2632. Epub 2018 Nov 5.

State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Key Laboratory of Veterinary Public Health of Agriculture Ministry, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.

The Qinghai-Tibet Plateau is a highly endemic area of alveolar echinococcosis where a series of intermediate hosts, especially voles and pikas, are infected with . The metacestodes of are fluid-filled, asexually proliferating cysts, and they are mainly found in the host's liver in the form of tumor-like growths. In this study, we investigated the genetic variations of in four mitochondrial (mt) genes, namely, NADH dehydrogenase subunit 5 (5), adenosine triphosphate subunit 6 (6), cytochrome c oxidase subunit 1 (1), and NADH dehydrogenase subunit 1 (1). Read More

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November 2018
5 Reads
3.941 Impact Factor

Hepatic echinococcosis: A review.

Ann Med Surg (Lond) 2018 Dec 2;36:99-105. Epub 2018 Nov 2.

Dept. of Paediatric Surgery, PGIMS Rohtak, Haryana, India.

Cystic echinococcosis (CE) is a widely endemic helminthic disease caused by infection with metacestodes (larval stage) of the Echinococcus granulosus tapeworm and transmitted by dogs. are common parasites in certain parts of the world, and are present on every continent with the exception of Antarctica. As a result, a large number of people are affected by CE. Read More

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December 2018
1 Read

First Case of Human Primary Vertebral Cystic Echinococcosis Due to .

J Clin Med 2018 Nov 15;7(11). Epub 2018 Nov 15.

Department of Parasitology and Mycology, University Hospital, F-21000 Dijon, France.

Cystic echinococcosis (CE) is a cosmopolitan parasitic zoonosis affecting more than one million people worldwide. In humans, primary bone CE is rare and involvement of is very uncommon. We report here the first case of primary vertebral cystic echinococcosis due to in Burgundy, France. Read More

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November 2018
3 Reads

Repeated Percutaneous Treatment of Massive Hepatic Cystic Echinococcosis in a Child.

Pediatrics 2018 Dec 14;142(6). Epub 2018 Nov 14.

Drinković Polyclinic, Zagreb, Croatia.

Because of mostly asymptomatic cyst growth and often-neglected nonspecific low-grade symptoms, many cases of cystic echinococcosis (CE) caused by in the pediatric population are diagnosed at school age, in an advanced and even complicated stage. In 2003, after 5 months of intermittent dull upper-right abdominal pain and nausea, a 13-year-old boy was diagnosed with massive liver CE, with ∼20 round-shaped double-walled medium-sized infective cysts, which permeated the whole liver. Because of their wide distribution across the liver tissue and the risky superficial position of some cysts, liver transplantation emerged as the optimal therapeutic option. Read More

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December 2018
2 Reads

Case Report: Percutaneous Treatment of Multiple Echinococcal Cysts Presenting as Abdominal Palpable Mass.

Am J Trop Med Hyg 2018 Nov 12. Epub 2018 Nov 12.

Department of Health Sciences, University of Florence, Anna Meyer Children's University Hospital, Florence, Italy.

We report the case of an adolescent Moroccan girl with abdominal pain and palpable mass in the upper right side of the abdomen. In the emergency department, an abdominal ultrasound showed hepatomegaly and eight active liver cysts, compatible with cystic echinococcosis. Serology for confirmed the diagnosis. Read More

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November 2018
2 Reads

Epidemiology, diagnosis, treatment and follow-up of cystic echinococcosis in asymptomatic carriers.

Trans R Soc Trop Med Hyg 2018 Nov 9. Epub 2018 Nov 9.

Hospital Rogelio Cortizo, Ingeniero Jacobacci.

Background: Río Negro Province is endemic for cystic echinococcosis (CE). A CE control program includes early diagnosis in humans. During 1980-1996, screening was done with serology and surgery was the unique choice of treatment. Read More

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November 2018
4 Reads

Human CD96 correlates to NK cell exhaustion and predicts the prognosis of human hepatocellular carcinoma.

Hepatology 2018 Nov 8. Epub 2018 Nov 8.

Division of Molecular Medicine, Hefei National Laboratory for Physical Sciences at Microscale, the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of China, Hefei, China.

Immune checkpoint blockade has become a promising therapeutic approach to reverse immune cell exhaustion. Co-inhibitory CD96 and TIGIT, together with co-stimulatory CD226, bind to common ligand CD155. The balancing between three receptors fine tunes the immune responses against tumors. Read More

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November 2018
9 Reads

In vivo therapeutic efficacy of the Allium sativum ME in experimentally Echinococcus granulosus infected mice.

Comp Immunol Microbiol Infect Dis 2018 Oct 13;60:23-27. Epub 2018 Oct 13.

Department of Pathobiology, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran. Electronic address:

Plant-based anthelmintics suggest an alternative treatment for cystic echinococcosis. The present study was conducted to evaluate the efficacy of methanolic extract (ME) of A. sativum (garlic) on the treatment of hydatid cysts in the murine model. Read More

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October 2018
3 Reads

Repurposing of an old drug: In vitro and in vivo efficacies of buparvaquone against Echinococcus multilocularis.

Int J Parasitol Drugs Drug Resist 2018 Dec 31;8(3):440-450. Epub 2018 Oct 31.

Institute of Parasitology, Vetsuisse Faculty, University of Bern, Länggassstrasse 122, 3012, Bern, Switzerland. Electronic address:

The metacestode stage of the fox tapeworm Echinococcus multilocularis causes the lethal disease alveolar echinococcosis. Current chemotherapeutic treatment options are based on benzimidazoles (albendazole and mebendazole), which are insufficient and hence alternative drugs are needed. In this study, we screened the 400 compounds of the Medicines for Malaria Venture (MMV) Pathogen Box against E. Read More

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December 2018
1 Read

Cystic Echinococcosis in immigrants and Italians accessing a single referral center in Lombardy, Italy.

Travel Med Infect Dis 2018 Nov 2. Epub 2018 Nov 2.

Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Viale Brambilla 74, 27100, Pavia, Italy; Unit of Infectious and Tropical Diseases, IRCCS San Matteo Hospital Foundation, Viale Taramelli 5, 27100, Pavia, Italy.

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November 2018
1 Read

Assessment of the global pattern of genetic diversity in Echinococcus multilocularis inferred by mitochondrial DNA sequences.

Vet Parasitol 2018 Oct 27;262:30-41. Epub 2018 Sep 27.

Department of Parasitology and Mycology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

The aim of this review was to assess our current knowledge on phylogeography and global genetic structure of Echinococcus multilocularis populations originating from rodents, wild canid hosts, and human. Six bibliographic databases were searched from 1990 to 2017, identifying a total of 110 publications. The cytochrome c oxidase subunit 1 (cox1) and cytochrome b (cytb) sequences of E. Read More

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October 2018
4 Reads
2.460 Impact Factor

Alveolar Echinococcosis Mimicking a Hepatic Neoplasm with Lymph Node Metastasis: A Case Report.

Case Rep Gastroenterol 2018 Sep-Dec;12(3):587-596. Epub 2018 Oct 2.

Department of Gastroenterology, Toyonaka Municipal Hospital, Toyonaka, Japan.

A 37-year-old man had an asymptomatic 17-mm mass in the liver by health check with ultrasonography. Five years later, he was referred to our hospital because the mass was slightly enlarged with a peripancreatic lymph node. We performed endoscopic ultrasonography fine-needle aspiration (EUS-FNA) to evaluate a lymph node, but it showed amorphous eosinophilic material and eosinophilic infiltrate in necrotic tissue of toothpaste-like white specimen. Read More

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October 2018
3 Reads

Geographic distribution of echinococcosis in Tibetan region of Sichuan Province, China.

Infect Dis Poverty 2018 Nov 2;7(1):104. Epub 2018 Nov 2.

Department of Parasitic Diseases, Sichuan Center for Disease Control and Prevention, No.6 Zhongxue Road, Chengdu, 610041, China.

Background: Echinococcosis is a parasitic zoonosis caused by Echinococcus larvae parasitism causing high mortality. The Tibetan Region of Sichuan Province is a high prevalence area for echinococcosis in China. Understanding the geographic distribution pattern is necessary for precise control and prevention. Read More

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November 2018
1 Read

A giant cystic echinococcosis of the lung in East Turkey.

Ann Med Surg (Lond) 2018 Dec 12;36:51-53. Epub 2018 Oct 12.

Anesthesiology Unit, Antalya Gazipaşa State Hospital, Cumhuriyet District, Hastane Street, 07900, Gazipaşa, Antalya, Turkey.

Introduction: Hydatid cyst disease is a zoonosis provoked by Echinoccocus.

Presentation Of Case: 17 year old male applied to our clinic with complaints of fatigue, lassitude, right chest pain and spitting of watery expectoration proceeding in 6 months. Computed tomographic scan indicated a 130*110 mm smooth contoured cavitary lesion located in the right middle lobe of the lung. Read More

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December 2018
1 Read

Remnant Liver-to-Standard Liver Volume Ratio Below 40% is Safe in Ex Vivo Liver Resection and Autotransplantation.

J Gastrointest Surg 2018 Oct 29. Epub 2018 Oct 29.

Department of Liver Surgery, Liver Transplantation Center, West China Hospital of Sichuan University, Chengdu, Sichuan Province, China.

Background: The successful application of ex vivo liver resection and autotransplantation (ERAT) has gained widespread attention for the treatment of end-stage hepatic alveolar echinococcosis, which is considered to be unresectable by conventional methods due to extensive invasion of the extra- and intrahepatic vasculature. However, data on remnant liver volume (RLV) are limited, and the safe volume limit of remnant liver is still unclear.

Methods: To determine the effect of liver volume in the technically developed era, we investigated the impact of the remnant liver-to-standard liver volume ratio (RLV/SLV) on the outcomes of ERAT. Read More

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October 2018
6 Reads

Comparison of the Utility of Recombinant B8/2 Subunit of the Antigen B, Native Antigen, and a Commercial ELISA Kit in the Diagnosis of Human Cystic Echinococcosis

Iran Biomed J 2018 Oct 28. Epub 2018 Oct 28.

Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: Cystic echinococcosis (CE) is a helminthic disease caused by the larval form of Echinococcus granulosus. In the present study, the B8/2 subunit of antigen B (AgB) of E. granulosus was expressed in E. Read More

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October 2018
3 Reads

Ultrasound and Cystic Echinococcosis.

Ultrasound Int Open 2018 Sep 23;4(3):E70-E78. Epub 2018 Oct 23.

Caritas-Krankenhaus, Medizinische Klinik 2, Bad Mergentheim, Germany.

The introduction of imaging techniques in clinical practice 40 years ago changed the clinical management of many diseases, including cystic echinococcosis (CE). For the first time cysts were clearly seen before surgery. Among the available imaging techniques, ultrasound (US) has unique properties that can be used to study and manage cystic echinococcosis. Read More

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September 2018
4 Reads

A Case of Echinococcal Cyst of the Lung.

Respir Med Case Rep 2018 10;25:286-292. Epub 2018 Oct 10.

Surat Municipal Institute of Medical Education and Research, Surat, Gujarat, India.

Echinococcosis, also known as Hydatid disease, is caused by the larvae of the tapeworm Echinococcus. It is globally prevalent and is a major clinical health concern. It is endemic in most underdeveloped regions including Asia, the Mediterranean, South America and Africa. Read More

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October 2018
8 Reads

Solitary hydatid cyst in the forearm: A case report.

Int J Surg Case Rep 2018 27;51:419-424. Epub 2018 Sep 27.

King Saud Medical City, Department of Orthopaedic Surgery, Riyadh, Saudi Arabia.

Introduction: Hydatid cyst is a parasitic disease caused by Echinococcus that is mostly found in the Mediterranean and Gulf States regions. Hydatid cysts usually arise in the liver and lungs but rarely occur in the forearm.

Presentation Of Case: In this report, we present a rare case of a solitary intramuscular forearm hydatid cyst in a 32-year-old woman. Read More

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September 2018
1 Read

Cardiac Echinococcosis Involving Left Ventricular Myocardium in an 18-Year-Old Patient.

Folia Med (Plovdiv) 2018 Jun;60(2):308-313

Department of Cardiovascular Surgery, Medical University of Plovdiv, Plovdiv, Bulagaria.

The hydatid disease is one of the most common tapeworm infections. It is caused most commonly by Echinococcus granulosus and has an endemic distribution. The transmission to humans, which are intermediate hosts, occurs by ingestion of contaminated food and water or by direct contact with infected animals. Read More

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June 2018
3 Reads

Identification of functional MKK3/6 and MEK1/2homologs from and investigation of protoscolecidal activity of MAPK signaling pathway inhibitors and .

Antimicrob Agents Chemother 2018 Oct 22. Epub 2018 Oct 22.

State Key Laboratory of Pathogenesis, Prevention, and Treatment of Central Asian High Incidence Diseases, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China

Cystic echinococcosis is a zoonosis caused by the larval stage of There is an urgent need to develop new drugs for the treatment of this disease. In this study, we identified two new members of MAPK cascades, MKK3/6 and MEK1/2 homologs (termed EgMKK1 and EgMKK2, respectively), from Both EgMKK1 and EgMKK2 were expressed at the larval stages. As shown by yeast two-hybrid and co-immunoprecipitation analyses, EgMKK1 interacted with the previously identified Egp38 but not with EgERK. Read More

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October 2018
4 Reads

The use of contrast-enhanced ultrasound (CEUS) for the diagnostic evaluation of hepatic echinococcosis.

Clin Hemorheol Microcirc 2018 Oct 15. Epub 2018 Oct 15.

Department of Radiology, Interdisciplinary Ultrasound-Center, Ludwig-Maximilians-University Munich - Grosshadern Campus, Munich, Germany.

Background: Hepatic echinococcosis (HE) is a zoonosis and depicts a rare but potentially lethal disease caused by larval infestation of E. multilocularis (alveolar echinococcosis, AE) and E. granulosus (cystic echinocococcosis, CE). Read More

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October 2018
1 Read

Correlation of radiological findings with surgical findings in hepatic hydatid disease. A prospective study of 79 cases.

Ann Ital Chir 2018 ;89:309-314

Objectives: The liver is the most frequent anatomic location of hydatid disease. Imaging modality nowadays are numerous and increasingly efficient. The objective of our study is to precise the correlation between Ultrasonography, computed tomography and intraoperative findings on the different characteristics of hepatic hydatid cyst. Read More

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January 2018
7 Reads

Should Paediatricians Be Aware of Cystic Echinococcosis? A Literature Review.

J Pediatr Gastroenterol Nutr 2018 Oct 16. Epub 2018 Oct 16.

Department of Health Sciences, University of Florence, Anna Meyer Children's University Hospital, Florence, Italy.

Among parasitic hepatic cystic lesions, the most common disease is represented by cystic echinococcosis, especially in high endemic countries. European epidemiology of cystic echinococcosis in children is very difficult to assess because of under-reporting but is increasing, because of high immigration flows from endemic countries and an increased awareness. Hydatidosis can be localized in every part of the body. Read More

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October 2018
3 Reads

Genetic characterization of human-derived hydatid fluid based on mitochondrial gene sequencing in individuals from northern and western China.

J Helminthol 2018 Oct 17:1-5. Epub 2018 Oct 17.

Laboratory of Molecular Medicine,Ordos Central Hospital,Ordos 017000,China.

This study investigated Echinococcus genotypes in patients with hydatidosis that reside in Inner Mongolia, Tibet or Qinghai Province by partially sequencing the cytochrome c oxidase subunit 1 (cox1) and NADH dehydrogenase 1 (nad1) genes. Cyst fluids were collected from 23 patients with hydatidosis and DNA was extracted. Portions of the cox1 and nad1 genes were amplified and subsequently sequenced. Read More

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October 2018
1 Read

Frequency and genetic diversity of Echinococcus granulosus sensu stricto in sheep and cattle from the steppe region of Djelfa, Algeria.

Parasitol Res 2018 Oct 16. Epub 2018 Oct 16.

Parasitology Unit (220B), Institute of Zoology, University of Hohenheim, Emil-Wolff-Str. 34, 70599, Stuttgart, Germany.

Cystic echinococcosis (CE) of humans and animals is caused by various species of Echinococcus granulosus sensu lato. Of these, E. granulosus sensu stricto has the widest geographical distribution and is the most important agent of human cystic echinococcosis. Read More

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October 2018
6 Reads

Hydatidosis of infratemporal fossa with proptosis - an unusual presentation: a case report and review of the literature.

J Med Case Rep 2018 Oct 17;12(1):309. Epub 2018 Oct 17.

Department of Pathology, Manipal Teaching Hospital / Manipal College of Medical Sciences, Pokhara, Nepal.

Background: Hydatid disease is one of the common zoonotic diseases caused by the larval stage of Echinococcus granulosus. It is endemic in sheep-raising and cattle-raising areas worldwide and humans are an accidental intermediate host following the ingestion of the larvae. Head and neck involvement of echinococcosis is a rare entity and involvement of the infratemporal region is extremely rare even in endemic areas. Read More

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October 2018
1 Read

Cystic Echinococcosis of the Bone in Kazakhstan.

Case Rep Infect Dis 2018 18;2018:9682508. Epub 2018 Sep 18.

Department of Visual Diagnostics, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan.

Cystic echinococcosis (CE) is a parasitic zoonosis caused by primarily affecting the liver and lungs. CE of the bone is by far the most debilitating form of the disease and is very difficult to manage as it mimics malignant tumors. We reviewed bone CE cases admitted to a reference oncological hospital in Kazakhstan from January 2010 to February 2017. Read More

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September 2018
2 Reads

Manifestation of hydatid cyst of liver with pancreatitis, cholangitis and jaundice: A case report.

J Pak Med Assoc 2018 Jul;68(7):1097-1099

Ziauddin University, Karachi.

Hydatid disease or echinococcosis, a systemic zoonosis is caused by Echinococcusgranulosus larvae. This is a common disease found all over the world, especially in the Mediterranean region. We report a 40 year old male with no known comorbids who came with complaints of fever with rigors and chills, right hypochondriac pain, and yellow discolouration of the sclera. Read More

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July 2018
6 Reads

Immunotherapy of alveolar echinococcosis via PD-1/PD-L1 immune checkpoint blockade in mice.

Parasite Immunol 2018 Dec 4;40(12):e12596. Epub 2018 Nov 4.

Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, Institute of Parasitology, University of Bern, Bern, Switzerland.

The growth potential of the tumour-like Echinococcus multilocularis metacestode (causing alveolar echinococcosis, AE) is directly dependent upon the nature/function of the periparasitic adaptive host immune-mediated processes. PD-1/PD-L1 pathway (programmed cell death 1), which inhibits lymphocytic proliferation in tumour development, is over-expressed at the chronic stage of AE. We tested the impact of a PD-1/PD-L1 pathway blockade on the outcome of both chronic AE (intraperitoneal metacestode inoculation, secondary AE and SAE) and acute AE (peroral egg infection, primary AE and PAE). Read More

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December 2018
4 Reads

Epidemiological survey on cystic echinococcosis in wild boar from Central Italy.

Parasitol Res 2018 Oct 12. Epub 2018 Oct 12.

Laboratory of Parasitology, Veterinary Teaching Hospital, Department of Veterinary Medicine, University of Sassari, Sassari, Italy.

Despite the wide distribution of wild boar populations in Italy and the increase of its diffusion in urbanized areas, only one case report has described the occurrence of Echinococcus granulosus s.l. in a wild boar from Marche (Central Italy). Read More

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October 2018
6 Reads

Clinical review of liver hydatid disease and its unusual presentations in developing countries.

Abdom Radiol (NY) 2018 Oct 10. Epub 2018 Oct 10.

Diagnostic Radiology Department, American University of Beirut Medical Center, Riad El Solh, PO Box 11-0236, Beirut, 1107 2020, Lebanon.

Human hydatid cyst disease is an international public health issue that particularly affects the developing countries. In this article, we discuss the epidemiology of hydatid disease in third world countries, the life cycle of echinococcus granulosus and how to make the clinical diagnosis of the disease, including laboratory tests and imaging modalities as well as uncommon presentation of this entity that we have encountered at the American University of Beirut Medical Center (AUBMC). We emphasize on the new World Health Organization classification of hepatic echinococcosis with examples from our clinical practice at AUBMC, and finally we describe the treatment, including medical and interventional therapies. Read More

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October 2018
1 Read

Disseminated cerebral hydatid disease (multiple intracranial echinococcosis).

Pract Neurol 2018 Oct 10. Epub 2018 Oct 10.

Imaging Department, University College Hospital, London, UK.

Intracranial echinococcosis is relatively uncommon and usually occurs in the context of echinococcal lesions elsewhere in the body, mostly liver and lung. Multiple intracranial lesions can result from rupture of an initial single intracranial cyst (in cystic echinococcosis) or from dissemination of systemic disease of the lung, liver or heart (cystic and alveolar echinococcosis). The two main subtypes, cystic and alveolar echinococcosis, present differently and have distinct imaging features in the brain. Read More

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October 2018
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Echinococcus granulosus hydatid cyst location is modified by Fasciola hepatica infection in cattle.

Parasit Vectors 2018 Oct 10;11(1):542. Epub 2018 Oct 10.

Escuela de Medicina Veterinaria, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago, Chile.

Background: Natural parasite infection occurs in wild and domestics animals with more than one parasite species at the same time, generating an infection called polyparasitism. Cystic echinococcosis reports are usually based only on infection with Echinoccocus granulosus leaving aside other internal parasitoses that could modulate both the immune response and pathogenesis of the natural infection. Fasciola hepatica is another cosmopolitan parasite in ruminants with a similar distribution to E. Read More

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October 2018
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Therapeutic and immunoregulatory effects of water-soluble alkaloids E2-a from Sophora moorcroftiana seeds as a novel potential agent against echinococcosis in experimentally protoscolex-infected mice.

Vet Res 2018 Oct 4;49(1):100. Epub 2018 Oct 4.

Department of Microbiology, Medical College, Northwest University for Nationalities, Lanzhou, 730030, China.

Novel compounds and more efficient treatment options are urgently needed for the treatment of cystic echinococcosis (CE), which is caused by Echinococcus granulosus. The decoction of Sophora moorcroftiana (Fabaceae) has been used to treat parasitosis for years in traditional Tibetan medicine. The aim of this study was to screen insecticidal water-soluble alkaloids from S. Read More

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October 2018
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