19,638 results match your criteria Echinococcosis


Retrospective Study of Cystic Echinococcosis in a Recent Cohort of a Referral Center for Liver Surgery.

J Gastrointest Surg 2018 Sep 21. Epub 2018 Sep 21.

Department of Infectious Diseases, Hospital Universitari Vall d'Hebron, PROSICS Barcelona, P° Vall d'Hebron 119-129, 08035, Barcelona, Spain.

Background: Cystic echinococcosis (CE) is a zoonosis endemic in Spain caused by the larval stage of the cestode Echinococcus granulosus and is one of the 18 neglected tropical diseases recognized by the WHO. The aim of this study was to describe the epidemiological and clinical data of CE in a surgical referral hospital.

Methods: A retrospective descriptive study of all adults' patients diagnosed with CE and followed at Vall d'Hebron University Hospital in Barcelona, Spain, between 2000 and 2015. Read More

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September 2018

Quantitative characterization and diagnosis via hard X-ray phase-contrast microtomography.

Microsc Res Tech 2018 Sep 20. Epub 2018 Sep 20.

Imaging Center, First Affiliated Hospital, Xinjiang Medical University, China.

Nondestructive three-dimensional (3D) micromorphological imaging technique is essential for hepatic alveolar echinococcosis (HAE) disease to determine its damage level and early diagnosis, assess relative drug therapy and optimize treatment strategies. However, the existing morphological researches of HAE mainly depend on the conventional CT, MRI, or ultrasound in hospitals, unfortunately confronting with the common limit of imaging resolution and sensitivity, especially for tiny or early HAE lesions. Now we presented a phase-retrieval-based synchrotron X-ray phase computed tomography (PR-XPCT) with striking contrast-to-noise ratio and high-density resolution to visualize the HAE nondestructive 3D structures and quantitatively segment different pathological characteristics of HAE lesions without staining process at the micrometer scale. Read More

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September 2018

Health-related quality of life in patients with alveolar echinococcosis: a cross-sectional study.

Infection 2018 Sep 17. Epub 2018 Sep 17.

Department of Internal Medicine III, Ulm University Hospital, Albert-Einstein-Allee 23, 89081, Ulm, Germany.

Purpose: The Alveolar echinococcosis (AE) is a rare zoonosis caused by the parasite Echinococcus multilocularis. To date, nothing is known about the health-related quality of life (HRQoL) in patients with AE. The aim of the study was to evaluate the HRQoL in patients with AE in comparison of the healthy population. Read More

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September 2018
3 Reads

A large cardiac hydatid cyst in the interventricular septum: A case report.

Int J Infect Dis 2018 Sep 12. Epub 2018 Sep 12.

Department of cardiovascular surgery, Sahloul Hospital, Ceinture Route, Sousse.

Isolated cardiac location is uncommon presentation of echinococcosis (0.5-2%) and involvement of the interventricular septum is even rarer. It may lead to various complications because of rupture and embolization. Read More

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September 2018
1 Read

Surgical approaches to hepatic hydatidosis ranging from partial cystectomy to liver transplantation.

Ann Hepatobiliary Pancreat Surg 2018 Aug 31;22(3):208-215. Epub 2018 Aug 31.

Institute of Liver Transplantation and Regenerative Medicine, Medanta The Medicity, Gurgaon, India.

Backgrounds/aims: A wide range of surgical approaches has been described for hepatic hydatidosis aiming primarily at the reduction of disease recurrence and minimization of postoperative morbidity.

Methods: A database analysis of patients with liver hydatidosis who underwent different surgical procedures between March 2010 and May 2016 was performed.

Results: A total of 21 patients with cystic echinococcosis (CE) and four cases of alveolar echinococcosis (AED) were detected. Read More

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August 2018
1 Read

Evaluation of the diagnostic value of the immunoblotting and ELISA tests using recombinant Em18 antigen in human alveolar echinococcosis from Xingjiang China.

Exp Ther Med 2018 Oct 1;16(4):3155-3160. Epub 2018 Aug 1.

State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830054, P.R. China.

Alveolar echinococcosis (AE) is a prevalent epidemic in the northern hemisphere, especially in central Europe and western China. Serum diagnosis is important for patients with AE, especially during the first screening. The present study purified the recombinant Em18-GST (rEm18-GST), and detected its diagnostic performance in human alveolar echinococcosis patients of Xinjiang, China with immunoblotting (IB) and enzyme-linked immunosorbent assay (ELISA). Read More

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October 2018
2 Reads

Corrigendum to "Alveolar echinococcosis: From a deadly disease to a well-controlled infection. Relative survival and economic analysis in Switzerland over the last 35 years" [J Hepatol 49 (2008) 72-77].

J Hepatol 2018 Sep 8. Epub 2018 Sep 8.

Gastroenterology and Hepatology, University Hospital of Zürich, Rämistrasse 100, Zürich CH-8091, Switzerland; Swiss HBP Center, University Hospital of Zürich, Rämistrasse 100, Zürich CH-8091, Switzerland. Electronic address:

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September 2018

Molecular Characterisation and Functions of Fis1 and PDCD6 Genes from .

Int J Mol Sci 2018 Sep 8;19(9). Epub 2018 Sep 8.

Department of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.

Cystic echinococcosis, a parasitic zoonosis that causes significant economic losses and poses a threat to public health, is caused by larvae of the tapeworm . Infection causes infertile cysts in intermediate hosts that cannot produce protoscoleces (PSCs) or complete the life cycle. Herein, we cloned, expressed, and characterised mitochondrial fission protein 1 () and programmed cell death protein 6 () from , and explored their functions related to infertile cysts. Read More

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September 2018
3 Reads

Genetic Diversity of Echinococcus granulosus Genotype G1 in Xinjiang, Northwest of China.

Korean J Parasitol 2018 Aug 31;56(4):391-396. Epub 2018 Aug 31.

School of Medicine, Shihezi University, Shihezi, Xinjiang Uygur Autonomous Region 832002, People's Republic of China.

Cystic echinococcosis (CE) caused by E. granulosus is a serious helminthic zoonosis in humans, livestock and wildlife. Xinjiang is one of high endemic province for CE in China. Read More

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A Retrospective Analysis on the Cystic Echinococcosis Cases Occured in Northeastern Punjab Province, Pakistan.

Korean J Parasitol 2018 Aug 31;56(4):385-390. Epub 2018 Aug 31.

Department of Parasitology, Faculty of Veterinary Medicine, University of Firat, 23119, Elazig, Turkey.

A retrospective study was performed to report the case occurrence of cystic echinococcosis (CE) in three hospitals of north-eastern region in Punjab Province, Pakistan. We reviewed retrospectively the clinical records of patients in 4 hospitals which were diagnosed with CE during 2012-2017. A total of 198 cases, 82 (41. Read More

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August 2018
1 Read

A chromatographic study on the retention behavior of the amylose tris(3-chloro-5-methylphenylcarbamate) chiral stationary phase under aqueous conditions.

J Sep Sci 2018 Sep 8. Epub 2018 Sep 8.

Dipartimento di Chimica e Tecnologie del Farmaco, "Sapienza" Università di Roma, Rome, Italy.

In this study, the retention properties of the immobilized polysaccharide-derived Chiralpak IG-3 chiral stationary phase under aqueous-organic conditions were investigated. A systematic evaluation of the retention factors of the enantiomers of the chiral sulfoxide oxfendazole, endowed with anthelmintic activity and selected as test compound, was carried out changing progressively the water content in hydro-organic eluents containing methanol, ethanol or acetonitrile. From the results obtained with acetonitrile-water mobile phases and the associated retention plots, clear U-shape retention dependencies, indicative of the interplay of both hydrophilic interaction liquid chromatography and reversed-phase modes, were highlighted. Read More

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September 2018
1 Read

Management of liver hydatid cyst with cystobiliary communication and acute cholangitis: a 27-year experience.

Eur J Trauma Emerg Surg 2018 Sep 6. Epub 2018 Sep 6.

Department of Radiology, Fattouma Bourguiba Hospital, Monastir, Tunisia.

Purpose: The rupture of the hydatid cyst into the bile ducts is a common and serious complication. The rupture can be latent or revealed after a complication such as acute cholangitis. The objective of this study was to discuss the clinical features, radiographic findings, and surgical treatment of this rare complication. Read More

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September 2018
2 Reads
0.38 Impact Factor

Evaluation of the recombinant antigens B2t and 2B2t, compared with hydatid fluid, in IgG-ELISA and immunostrips for the diagnosis and follow up of CE patients.

PLoS Negl Trop Dis 2018 Sep 6;12(9):e0006741. Epub 2018 Sep 6.

Instituto de Recursos Naturales y Agrobiología de Salamanca (IRNASA-CSIC), Salamanca, Spain.

Cystic echinococcosis (CE) is one of the most widespread helminthic zoonoses and is caused by the tapeworm Echinococcus granulosus complex. CE diagnosis and monitoring primarily rely on imaging techniques, complemented by serology. This is usually approached by the detection of IgG antibodies against hydatid fluid (HF), but the use of this heterogeneous antigenic mixture results in a variable percentage of false positive and negative results, and has shown to be useless for follow-up due to the long persistence of anti-HF antibodies in cured patients. Read More

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September 2018
1 Read

[Cardiac Hydatid Cyst in a Child: A Case Report].

Rev Peru Med Exp Salud Publica 2018 Apr-Jun;35(2):338-343

Servicio de Clínica Pediátrica, Hospital Nacional Guillermo Almenara Irigoyen. Lima, Perú.

Echinococcosis is a parasitic infection caused by Echinococcus granulosus, which, in its cystic state, forms the socalled hydatid cyst. It presents important morbidity, with possible sequelae related to the location, and high costs due to surgical and prolonged pharmacological treatment. The liver and the lung are the most common anatomical locations, and much rarer are the kidney, spleen, brain, and heart, where the latter represents 0. Read More

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November 2017
2 Reads

New Options in the Management of Cystic Echinococcosis - A Single Centre Experience Using Minimally Invasive Techniques.

Chirurgia (Bucur) 2018 Jul-Aug;113(4):486-496

Objective: The aim of this study is to verify if the experience on 4 years in using minimally invasive techniques in the treatment of CE could match regarding the indications and results with the major studies on topic.

Method: During 03.2014 - 03. Read More

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August 2018
1 Read

Unexpected infections in shepherd dogs and wolves in south-western Italian Alps: A new endemic area?

Int J Parasitol Parasites Wildl 2018 Dec 13;7(3):309-316. Epub 2018 Aug 13.

Department of Veterinary Science, University of Pisa, Pisa, Italy.

The European distribution of has been reported to be expanding east and north, whereas its southern limits are deemed stable. During a study on s.l. Read More

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December 2018

Unexpected Diagnosis in Gluteal Region -A Primary Intramuscular Hydatid Cyst: A Case Report.

J Orthop Case Rep 2018 Mar-Apr;8(2):104-106

Department of Orthopeadic Surgery Haydarpasa Numune Training and Research Hospital, Üsküdar, İstanbul.

Introduction: Primary hydatid cyst is rarely seen in musculoskeletal system. This paper presents a case of an intramuscular hydatid cyst in gluteal region.

Case Of Report: We present the case of a 36-year-old woman affected by pain and a mass in her right gluteal region. Read More

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September 2018
4 Reads

Echinococcosis in Tambool, Central Sudan: a knowledge, attitude and practice (KAP) study.

Int Health 2018 Aug 25. Epub 2018 Aug 25.

Centre of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

Introduction: In Sudan, echinococcosis (EC) is a chronic neglected zoonotic parasitic disease caused by Echinococcus granulosus. Studies have shown high prevalence rates in dogs (50-70%), camels (35%) and sheep, goats and cattle (10-11%). In total, 0. Read More

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August 2018
4 Reads

Canine parasitic zoonoses in India: status and issues.

Rev Sci Tech 2017 Dec;36(3):817-830

Dogs play valuable roles in human society. In addition to serving as pets and companions, dogs have also been important in hunting and, in recent times, as therapy animals. In India, the number of pet dogs is estimated to be around 5 million. Read More

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December 2017
3 Reads

Structure-Based Drug Design of Potent Pyrazole Derivatives against Rhinovirus Replication.

J Med Chem 2018 Sep 7. Epub 2018 Sep 7.

Aix-Marseille Univ, Institut de Chimie Radicalaire , Laboratoire de Pharmacochimie Radicalaire , UMR 7273 CNRS, 27 Boulevard Jean Moulin , 13385 Marseille , Cedex 05 , France.

Rhinoviruses (RVs) have been linked to exacerbations of many pulmonary diseases, thus increasing morbidity and/or mortality in subjects at risk. Unfortunately, the wide variety of RV genotypes constitutes a major hindrance for the development of Rhinovirus replication inhibitors. In the current investigation, we have developed a novel series of pyrazole derivatives that potently inhibit the Rhinovirus replication. Read More

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September 2018
3 Reads

Walk together to combat echinococcosis.

Lancet Infect Dis 2018 Sep;18(9):946

Key Laboratory of Parasite and Vector Biology, Ministry of Health, Shanghai, China; National Center for International Research on Tropical Diseases, Shanghai, China; WHO Collaborating Center for Tropical Diseases, Shanghai, China; National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai 200025, China. Electronic address:

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September 2018
5 Reads

Editorial.

Authors:
John Horton

Am J Trop Med Hyg 2018 Aug 20. Epub 2018 Aug 20.

Tropical Projects, Hitchin, United Kingdom.

Although albendazole has been available for human use since 1982 and used for echinococcosis since the mid-1980s, for the most part, it is only approved for the treatment of intestinal helminth diseases as a single dose. Thus, in most countries, the only available presentation is a single 400-mg tablet or two 200-mg tablets. Albendazole is, however, a recommended treatment for several parasitic diseases for which multiple doses are required, and thus, it is often necessary to provide medication in a nonstandard manner. Read More

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August 2018
1 Read

Unusual retention behavior of omeprazole and its chiral impurities B and E on the amylose tris (3-chloro-5-methylphenylcarbamate) chiral stationary phase in polar organic mode.

J Pharm Anal 2018 Aug 20;8(4):234-239. Epub 2018 Apr 20.

Centro nazionale per il controllo e la valutazione dei farmaci, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

Recent reports have demonstrated that the new commercially available immobilized-type chiral stationary phases (CSPs) containing amylose tris(3-chloro-5-methylphenylcarbamate) (ACMPC) as a selector exhibit not only an exceptionally high enantioselectivity in high-performance liquid chromatography (HPLC) but they are also applicable to a wide range of chiral analytes. Herein, we report the results obtained in the HPLC analysis of omeprazole and its impurities B and E on the ACMPC-based Chiralpak IG-3 CSP (CSP) under polar organic conditions. A systematic evaluation of the retention characteristics of the selected benzimidazole chiral probes was carried out by changing the composition of the mobile phase and the column temperature. Read More

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Molecular and functional characterization of glucose transporter genes of the fox tapeworm Echinococcus multilocularis.

Mol Biochem Parasitol 2018 Aug 18;225:7-14. Epub 2018 Aug 18.

Laboratory of Medical Zoology, Nihon University College of Bioresource Sciences, Fujisawa, Kanagawa 252-0880, Japan. Electronic address:

Alveolar echinococcosis (AE) is a zoonotic parasitosis caused by larvae of the fox tapeworm, Echinococcus multilocularis. E. multilocularis is distributed widely in the Northern hemisphere, causing serious health problems in various animals and humans. Read More

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August 2018
3 Reads

Clinical management of cystic echinococcosis: state of the art and perspectives.

Curr Opin Infect Dis 2018 Oct;31(5):383-392

Section Clinical Tropical Medicine.

Purpose Of Review: This review draws attention to patients with cystic echinococcosis migrating from highly endemic to non-endemic countries with limited experience in cystic echinococcosis management, to ultrasound-based cyst staging, and to the WHO cyst classification as a powerful, to date underused tool to triage patients into the four currently available treatment modalities.

Recent Findings: In non- and low-prevalence countries, cystic echinococcosis is often misclassified. Differential diagnoses, such as simple cysts and other benign and malignant space-occupying lesions, have similar appearances on imaging. Read More

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October 2018

A report on three patients with Echinococcus multilocularis: Lessons learned.

Indian J Gastroenterol 2018 Aug 18. Epub 2018 Aug 18.

Fortis Escorts Heart Institute, Okhla Road, New Delhi, 110 025, India.

Echinococcus multilocularis (EM) is the most virulent species of the genus Echinococcus. It causes a highly lethal helminthic disease in humans. The disease may present as hepatic mass mimicking a malignant neoplasm. Read More

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August 2018
6 Reads

A giant pulmonary cyst hydatid imitating plevral effusion.

Int J Surg Case Rep 2018 Aug 9;50:126-129. Epub 2018 Aug 9.

Department of Anesthesiology, Aydın Menderes University, Medical Faculty Zafer District, 09100 Efeler, Aydın, Turkey.

Introduction: Cystic echinococcosis is an endemic disease in east Turkey. Echinococcosis granulosus is reported as the most common agent of cystic echinoccocus. Hydatid cysts are generally involved in lung and liver. Read More

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August 2018
2 Reads

Geographical Environment Factors and Risk Mapping of Human Cystic Echinococcosis in Western China.

Int J Environ Res Public Health 2018 Aug 12;15(8). Epub 2018 Aug 12.

Institute of Geodesy and Geophysics, Chinese Academy of Sciences, Wuhan 430077, China.

The study aimed to reveal the risk factors and predict the prevalence of human cystic echinococcosis (CE) in Western China. To do this, we analyzed county-wide data relating to the prevalence of human CE in seven provinces of Western China, along with associated human, natural geographical environmental data. We then used spatial analysis and multiple regression analysis to investigate the correlation between the prevalence of human CE and associated environmental factors and to create a risk map of the disease in the seven provinces. Read More

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Efficiency of flubendazole-loaded mPEG-PCL nanoparticles: A promising formulation against the protoscoleces and cysts of Echinococcus granulosus.

Acta Trop 2018 Nov 9;187:190-200. Epub 2018 Aug 9.

Department of Biological statistics and Epidemiology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.

None of the existing drugs can effectively treat the human cystic echinococcosis. This study aimed to improve the efficacy of flubendazole (FLBZ) against the protoscoleces and cysts of Echinococcus granulosus by preparing polymeric FLBZ-loaded methoxy polyethylene glycol-polycaprolactone (mPEG-PCL) nanoparticles. The protoscoleces and microcysts were treated with FLBZ-loaded mPEG-PCL nanoparticles (FLBZ-loaded nanoparticles) and free FLBZ at the final concentrations of 1, 5, and 10 μg/mL for 27 and 14 days, respectively. Read More

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November 2018
4 Reads

Patients with cystic echinococcosis in the three national referral centers of Mongolia: A model for CE management assessment.

PLoS Negl Trop Dis 2018 Aug 9;12(8):e0006686. Epub 2018 Aug 9.

Section Clinical Tropical Medicine, University Hospital Heidelberg, Heidelberg, Germany.

Background: Mongolia is one of the endemic countries for cystic echinococcosis (CE), a zoonotic disease caused by the larval stage of Echinococcus granulosus. The goal of this study is to describe the current clinical management of CE in Mongolia, to capture the distribution of cyst stages of patients treated, and to contrast current practice with WHO-IWGE expert consensus.

Methods: Hospital records of CE patients treated between 2008 and 2015 at the three state hospitals and fulfilling the inclusion criterion 'discharge diagnosis CE' (ICD 10 code B. Read More

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Estimating the prevalence of Echinococcus in domestic dogs in highly endemic for echinococcosis.

Infect Dis Poverty 2018 Aug 9;7(1):77. Epub 2018 Aug 9.

The Human Pathology and Immunology Department, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, People's Republic of China.

Background: Cystic echinococcosis (CE) and alveolar echinococcosis (AE) are highly endemic in Xiji County of Ningxia Hui Autonomous Region (NHAR) in China where the control campaign based on dog de-worming with praziquantel has been undertaken over preceding decades. This study is to determine the current prevalence of Echinococcus granulosus and E. multilocularis in domestic dogs and monitor the echinococcosis transmission dynamics. Read More

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August 2018
9 Reads

Whole genome analysis of codon usage in Echinococcus.

Mol Biochem Parasitol 2018 Aug 3;225:54-66. Epub 2018 Aug 3.

IMPaM, CONICET, Facultad de Medicina, Universidad de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina. Electronic address:

The species of the genus Echinococcus are parasitic platyhelminths that cause echinococcosis and exert a global burden on public and animal health. Here we performed codon usage bias and comparative genomic analyses using whole genome and expression data of three Echinococcus species. The study of 4,710,883 codons, two orders of magnitude more than in previous research works, showed that the codon usage in Echinococcus genes is biased towards the pyrimidines T and C ending codons, with an average effective number of codons equal to 57 revealing a low codon usage bias. Read More

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Comparison of [F]Fluorodeoxyglucose Positron Emission Tomography and Contrast-Enhanced Ultrasound for Evaluation of Hepatic Alveolar Echinococcosis Activity.

Ultrasound Med Biol 2018 Aug 1. Epub 2018 Aug 1.

Department of Ultrasonography, First Affiliated Hospital, Xinjiang Medical University, Urumqi, China. Electronic address:

The mean gray-scale ratio of the infiltrating zone of a lesion to the surrounding normal liver tissue was evaluated on the basis of contrast enhancement of the infiltration and proliferation zones of a hepatic alveolar echinococcosis lesion. The results were compared with the maximum standardized uptake value (SUVmax) of [F]fluorodeoxyglucose positron emission tomography/computed tomography ([F]FDG PET-CT), and the application of contrast-enhanced ultrasound in evaluating hepatic alveolar echinococcosis activity is discussed. The 36 patients with hepatic alveolar echinococcosis recruited underwent contrast-enhanced ultrasound and [F]FDG PET-CT. Read More

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August 2018
1 Read

Rural and urban distribution of wild and domestic carnivore stools in the context of Echinococcus multilocularis environmental exposure.

Int J Parasitol 2018 Aug 2. Epub 2018 Aug 2.

Chrono-environnement, UMR UBFC/CNRS 6249 aff. INRA, University of Bourgogne Franche-Comté, 25030 Besançon, France.

In zoonotic infections, the relationships between animals and humans lead to parasitic disease with severity that ranges from mild symptoms to life-threatening conditions. In cities and their surrounding areas, this statement is truer with the overcrowding of the protagonists of the parasites' life cycle. The present study aims to investigate the distribution of a parasite, Echinococcus multilocularis, which is the causative agent of alveolar echinococcosis, using copro-sampling in historically endemic rural settlements of the eastern part of France and in newly endemic areas including urban parks and settlements surrounding Paris. Read More

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August 2018
1 Read
3.87 Impact Factor

[Major liver resections in cystic echinococcosis of the liver].

Chirurg 2018 Sep;89(9):735

Klinik für Allgemein‑, Viszeral- und Gefäßchirurgie, Universitätsklinikum Jena, Am Klinikum 1, 07747, Jena, Deutschland.

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September 2018

Characterization of cellular and humoral immune responses to alkaline phosphatase from fertile hydatid cysts in the human peripheral blood.

J Cell Physiol 2018 Aug 2. Epub 2018 Aug 2.

Immunology Research Center, Iran University of Medical Sciences, Tehran, Iran.

Hydatid cyst, the larval stage of the tapeworm Echinococcus granulosus and a causative agent of cystic echinococcosis, possesses a vast number of antigenic peptides that are constantly presented in the host immune system during infection. Here, we sought to provide more information about the cellular/humoral components engaged in the peripheral immune reactions to the fertile-cyst-derived Echinococcus alkaline phosphatase (E.ALP) in human hosts. Read More

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August 2018
1 Read

Retrospective Evaluation of Patients Diagnosed with Cystic Echinococcosis at Kafkas University Faculty of Medicine's Surgical Outpatients Unit.

Turkiye Parazitol Derg 2018 Apr 18. Epub 2018 Apr 18.

Department of Urology, Kafkas University School of Medicine, Kars, Turkey.

Objective: The aim of this study was to retrospectively evaluate the serological and radiological analysis and medical and surgical treatment results of patients diagnosed with cystic echinococcosis (CE).

Methods: Records belonging to a total of 67 patients diagnosed with CE who presented to the Kars Kafkas University Faculty of Medicine Research Hospital's Surgical Outpatient unit between January 2012 and December 2015 were retrospectively evaluated.

Results: Of 67 CE cases, 53 (79. Read More

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Retrospective Evaluation of Anti-Toxoplasma gondii Antibody Among First Trimester Pregnant Women Admitted to Nenehatun Maternity Hospital between 2013-2017 in Erzurum.

Turkiye Parazitol Derg 2018 Jun;42(2):118-121

Adnan Menderes Üniversitesi Tıp Fakültesi, Tıbbi Parazitoloji Anabilim Dalı, Aydın, Türkiye.

Objective: Echinococcus granulosus, the etiological agent of cystic echinococcosis (CE) in humans and livestock, is a widely distributed zoonotic pathogen tapeworm. The infection is transmitted to humans by the ingestion of E. granulosus eggs released in the feces of definitive hosts such as dogs. Read More

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June 2018
3 Reads

[Large multicystic space-occupying liver lesion in a 19-year-old woman].

Internist (Berl) 2018 Aug 1. Epub 2018 Aug 1.

Abteilung I (Innere Medizin), Bundeswehrkrankenhaus Berlin, Scharnhorststr. 13, 10115, Berlin, Deutschland.

A 19-year-old woman presented with liver capsule pain and a liver lesion on sonography, which contained microvesicular cystic, necrotic and solid fibrotic formations typical for alveolar echinococcosis (AE). The diagnosis was confirmed by serology and histopathology. This parasitic infection which is endemic in Germany is feared because of its malignant growth. Read More

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August 2018
2 Reads

Epidemiology and Clinical Features of Hydatid Cyst in Northern Iran from 2005 to 2015.

Iran J Parasitol 2018 Apr-Jun;13(2):310-316

Pediatric Infectious Diseases Research Center, Mazandaran University of Medical Sciences, Sari, Iran.

Background: Human hydatid disease imposes significant impacts on public health by producing substantial morbidity and mortality in involved communities. This study aimed to evaluate the epidemiology and clinical features of hydatid cyst in northern Iran as a breeding center for the infection.

Methods: In this cross-sectional study, the hospital records of all hydatidosis-affected patients admitted in three teaching hospitals of Mazandaran Province between Mar 2005-2015 were reviewed. Read More

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August 2018
4 Reads

A systematic review on modelling approaches for economic losses studies caused by parasites and their associated diseases in cattle.

Parasitology 2018 Aug 2:1-13. Epub 2018 Aug 2.

Laboratoire de Parasitologie,École Nationale de Médecine Vétérinaire, Univ. Manouba,2020 Sidi Thabet,Tunisia.

Parasites reside inside or outside their hosts and get host nutrition and blood. Here, we have emphasized economic losses in cattle caused by parasitic diseases due to ecto- and endo- parasites (flies, ticks, mites and helminths). We have outlined different methods/models including economic evaluation techniques and dynamic analysis as a major class, used for the calculation of economic losses caused by parasites in cattle. Read More

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August 2018
1 Read

Gut microbiome analysis as a tool towards targeted non-invasive biomarkers for early hepatocellular carcinoma.

Gut 2018 Jul 25. Epub 2018 Jul 25.

Department of Hepatobiliary and Pancreatic Surgery, the First Affiliated Hospital, School of Medicine, Zhejiang University; Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Hangzhou, China.

Objective: To characterise gut microbiome in patients with hepatocellular carcinoma (HCC) and evaluate the potential of microbiome as non-invasive biomarkers for HCC.

Design: We collected 486 faecal samples from East China, Central China and Northwest China prospectively and finally 419 samples completed Miseq sequencing. We characterised gut microbiome, identified microbial markers and constructed HCC classifier in 75 early HCC, 40 cirrhosis and 75 healthy controls. Read More

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July 2018
3 Reads
14.66 Impact Factor

Multiple zoonotic helminth infections in domestic dogs in a rural area of Khuzestan Province in Iran.

BMC Vet Res 2018 Jul 25;14(1):224. Epub 2018 Jul 25.

Infectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Background: Echinococcosis and toxocarosis caused by the genus of Echinococcus and Toxocara spp. are among important helminthic diseases worldwide. Limited data on the prevalence of these parasites persuaded us to determine the prevalence of E. Read More

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July 2018
5 Reads

Could beta-myrcene be an alternative to albendazole for the treatment of experimental cystic echinococcosis?

Acta Trop 2018 Nov 21;187:5-12. Epub 2018 Jul 21.

Laboratorio de Zoonosis Parasitarias, Instituto de Investigaciones en Producción, Sanidad y Ambiente (IIPROSAM), Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Mar del Plata, Funes 3250, 7600, Mar del Plata, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina. Electronic address:

Echinococcus granulosus causes hydatidosis or cystic echinococcosis in humans and livestock. In humans, this disease can be managed with surgery, percutaneous treatment, chemotherapy and/or observation. The chemotherapeutic agents used and approved for treatment of hydatidosis are benzimidazoles. Read More

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November 2018
1 Read

Shortage of Albendazole and Its Consequences for Patients with Cystic Echinococcosis Treated at a Referral Center in Italy.

Am J Trop Med Hyg 2018 Jul 23. Epub 2018 Jul 23.

Unit of Infectious and Tropical Diseases, IRCCS San Matteo Hospital Foundation, Pavia, Italy.

Albendazole (ABZ) is the best drug available to treat cystic echinococcosis (CE), a neglected tropical disease. Cystic echinococcosis patients often receive a continuous course of the drug for 6-12 months. In Italy, ABZ shortages occur almost on a yearly basis. Read More

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July 2018
1 Read

Foxp3 T Regulatory Cells as a Potential Target for Immunotherapy against Primary Infection with Echinococcus multilocularis Eggs.

Infect Immun 2018 Oct 21;86(10). Epub 2018 Sep 21.

Institute of Parasitology, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland

Alveolar echinococcosis (AE) is a lethal disease caused by infection with the metacestode stage of the helminth , which develops into a tumorlike mass in susceptible intermediate hosts. The growth potential of this parasite stage is directly linked to the nature of the surrounding periparasitic immune-mediated processes. In a first step (experiment 1), mice were orally infected with eggs, to be used for assessing the hepatic expression profiles of 15 selected cytokine and chemokine genes related to acquired immunity from 21 to 120 days postinfection. Read More

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October 2018
8 Reads

Th1/Th2-type cytokine profile in C57 black mice inoculated with live Echinococcus granulosus protoscolices.

J Infect Public Health 2018 Jul 19. Epub 2018 Jul 19.

Department of Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address:

Background And Objective: Cystic echinococcosis (CE) is a widespread parasitic disease caused by infection with the larval stage of a tapeworm, Echinococcus granulosus. The immune response to hydatid cyst in intermediate hosts is a complex and contradictory issue. It is suggested that a Th2 response would favor the establishment of the parasite, whereas a Th1 response would be lethal for the parasite. Read More

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Effect of the transversus abdominis plane block on postoperative pain and recovery in patients with hepatic echinococcosis.

J Int Med Res 2018 Sep 23;46(9):3563-3569. Epub 2018 Jul 23.

1 Department of Anesthesiology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu 610072, Sichuan, P.R. China.

Objectives Hepatic echinococcosis (HE) is a severe parasitic disease that occurs worldwide, and radical surgery is the recommended therapy. This study was performed to investigate the efficacy of using a transversus abdominis plane (TAP) block during surgery on postoperative pain and recovery of patients with HE under the guidelines of an enhanced recovery after surgery (ERAS) protocol. Methods Fifty-eight patients from the Tibetan plateau who underwent surgery for treatment of HE by the same surgeons under the guidance of ERAS were included in the present study. Read More

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September 2018
1 Read

Ex vivo Liver Resection and Autotransplantation as Alternative to Allotransplantation for End-stage Hepatic Alveolar Echinococcosis.

J Hepatol 2018 Jul 19. Epub 2018 Jul 19.

State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Xinjiang Medical University, Urumqi, China; Centre of Digestive and Vascular Surgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China. Electronic address:

Background & Aims: Radical resection is the best treatment for advanced hepatic alveolar echinococcosis (AE) patients. Liver transplantation is considered for selected advanced cases; however, shortage of organ donor and risk for post-operative recurrence remain challenging. The present prospective study assessed 69 end-stage patients treated by ex vivo liver resection and autotransplantation. Read More

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July 2018
5 Reads