21,738 results match your criteria Echinococcosis

Laparoscopic Treatment Strategies for Liver Echinococcosis.

Infect Dis Ther 2022 Jun 25. Epub 2022 Jun 25.

Department of General Surgery, The General Hospital of Western Theater command, Chengdu, 610083, People's Republic of China.

Liver echinococcosis is clinically mainly composed of hepatic cystic echinococcosis (CE) and hepatic alveolar echinococcosis (AE). At present, laparoscopy has been comprehensively applied in the treatment of two types of liver echinococcosis. For hepatic CE treatment, both laparoscopic total pericystectomy and laparoscopic hepatectomy can achieve radical results, but the former is considered the first choice owing to its being more minimally invasive; laparoscopic subtotal pericystectomy and laparoscopic partial pericystectomy can be accepted as complementary options, considering the presence of complicated cysts and the level of laparoscopic technique in remote hospitals; laparoscopic cystectomy is simple, but it is not currently recommended for treatment of hepatic CE owing to poor efficacy and high risk of postoperative complications. Read More

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Evaluation of serum indirect haemagglutination test results of suspected cystic echinococcosis cases from 2009-2017.

J Pak Med Assoc 2022 Jun;72(6):1035-1038

Department of Medical Microbiology, Uludag University, Bursa, Turkey.

Objective: This study aims to evaluate the serological, radiological and epidemiological analysis of suspected cystic echinococcosis patients, and to assess the positivity rate in the region.

Methods: The retrospective study was conducted at Bursa Uludag University Hospital, Turkey and comprised data from January 2009 to December 2017 related to patients of either gender with suspected cystic echinococcosis who underwent indirect haemagglutination testing. Demographic and clinical data of patients who tested positive were analysed. Read More

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Antitumor Effect of Pseudolaric Acid B Involving Regulation of Notch1/Akt Signaling Response in Human Hepatoma Cell In Vitro.

Evid Based Complement Alternat Med 2022 14;2022:5353686. Epub 2022 Jun 14.

School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, Gansu, China.

Background: Liver cancer, particularly hepatocellular carcinoma (HCC), is the fourth leading cause of cancer-related death worldwide. Sorafenib is a crucial drug for the treatment of advanced HCC, but it is difficult to meet the challenge of increasing clinical demands due to its severe side effects and drug resistance. Hence, development of novel antitumor drugs is urged. Read More

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Bacterial and Fungal Occurrence in Hydatid Cysts from Livestock in Central Iran.

Vet Res Commun 2022 Jun 22. Epub 2022 Jun 22.

Research Center for Food Hygiene and Safety, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Echinococcus granulosus sensu lato causes Cystic echinococcosis. This study investigated the bacterial and fungal species in the liver and lung hydatid cysts obtained from sheep, goats, cattle, and camels slaughtered in Yazd abattoir, Central Iran. In this study, 84 hydatid cysts were obtained from 20 sheep, 13 goats, 25 cattle, and 26 camels. Read More

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Tim-3/Galectin-9 signaling pathway is involved in the cytokine changes in mice with alveolar echinococcosis.

Mol Biol Rep 2022 Jun 17. Epub 2022 Jun 17.

Department of Immunology, College of Basic Medicine, Xinjiang Medical University, No. 393, Xinyi Road, 830011, Urumqi, Xinjiang, China.

Background: Tim-3/Galectin-9 is involved in the immune escape of many pathogens. However, the role of Tim-3/Galectin-9 in persistent infection of Echinococcus multilocularis (Em), which is related to immune escape, is still unclear.

Objective: To investigate the role of Tim-3/Galectin-9 and related cytokines in mice with persistent infection of Em. Read More

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New-onset axillary lymphangioma: a case report.

J Med Case Rep 2022 Jun 19;16(1):242. Epub 2022 Jun 19.

Department of Surgery, Banner MD Anderson Cancer Center-Phoenix, University of Arizona College of Medicine-Phoenix, 925 East McDowell Rd., Phoenix, AZ, 85006, USA.

Background: Lymphangioma is a rare diagnosis in adult patients and typically presents in early infancy. These tumors are a result of malformation of the lymphatic vessels and usually involve the head, neck, and axilla.

Case Presentation: We report the case of a 28-year-old African female who recently immigrated from East Africa and presented to our surgical breast clinic with a large and rapidly growing left axillary mass. Read More

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A Case of Extensive Thoracolumbar Spinal Intradural Cystic Echinococcosis.

World Neurosurg 2022 Jun 14. Epub 2022 Jun 14.

Department of Neurosurgery, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China. Electronic address:

Spinal cystic echinococcosis (CE) is a rare but devastating form of a neglected parasitic disease caused by the larval stage of the cestode Echinococcus granulosus. CE or hydatid disease, most commonly affects the liver and lungs. Spinal CE occurs in less than 1% of all cases. Read More

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Comment on: Unfamiliar liver lesions.

Br J Surg 2022 Jun 17. Epub 2022 Jun 17.

Department of Hepatobiliary and Pancreatic Surgery, Qinghai University Affiliated Hospital, Xining, China.

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Long-term postoperative outcomes of Roux-en-Y cholangiojejunostomy in patients with benign biliary stricture.

BMC Surg 2022 Jun 16;22(1):231. Epub 2022 Jun 16.

Department of Hepatobiliary and Echinococcosis Surgery, Digestive and Vascular Surgery Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830054, Xinjiang, China.

Background: Although there are common postoperative complications, Roux-en-Y cholangiojejunostomy is still broadly used as a standard surgical procedure for patients with biliary stricture. This study aimed to explore long-term risk factors of cholangiojejunostomy in patients with biliary stricture who underwent revisional cholangiojejunostomy.

Methods: Clinical data of 61 patients with biliary stricture undergoing revisional cholangiojejunostomy were retrospectively analyzed. Read More

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Chemical and physical features of biological fluids in treatment of hydatid disease.

Braz J Biol 2022 13;84:e257021. Epub 2022 Jun 13.

Kazan Federal University, Kazan, Russia.

The aim of this paper is to better understand the dynamics of crystallogenic and starting activity in biological fluids of patients throughout surgery and the late postoperative phase in alveococcosis. Samples of saliva from 22 individuals with alveococcosis were included in the research. Biological fluid samples were taken at the time of admission and before the patient was discharged. Read More

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A Retrospective Evaluation of Spleen Hydatid Cyst Treatments: The Spleen-Preserving Conservative Approach is Preferable to Splenectomy.

Eurasian J Med 2022 Jun;54(2):133-137

Department of General Surgery, Atatürk University Faculty of Medicine, Erzurum, Turkey.

Objective: Cystic echinococcosis (CE) is rarely encountered in the spleen, even in areas where the disease is endemic. There is no consensus in the literature concerning the treatment of splenic cystic echinococcosis. This study was intended to compare the treatment results and factors affecting the selection of the spleen- preserving approach or splenectomy in treatment. Read More

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Comparative study of indocyanine green (ICG)-R15 and Albumin-Indocyanine Green Evaluation (ALICE) grading system in the prediction of posthepatectomy liver failure and postoperative mortality in patients with hepatic alveolar echinococcosis.

BMC Gastroenterol 2022 Jun 14;22(1):297. Epub 2022 Jun 14.

Department of Hepatobiliary-Pancreatic Surgery, Cell Transplantation Center, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, No. 32, West Second Section, First Ring Road, Qingyang District, Chengdu, 610072, Sichuan, China.

Background: A precise evaluation of liver reserve function in patients with hepatic alveolar echinococcosis (HAE) prior to hepatectomy could substantially increase the success rate of the operation and reduce the incidence of postoperative complications. The present study aimed to investigate the significance of the indocyanine green retention test at 15 min (ICG-R15) and the Albumin-Indocyanine Green Evaluation (ALICE) grading system in predicting severe posthepatectomy liver failure (PHLF) and postoperative mortality in HAE patients undergoing liver resection.

Methods: A total of 105 HAE patients undergoing hepatectomy were enrolled in this study. Read More

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Expression and production of protoscolex recombinant P29 protein and its serological evaluation for diagnosis of human hydatidosis.

J Parasit Dis 2022 Jun 29;46(2):377-383. Epub 2021 Sep 29.

Laboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran.

Cystic Echinococcosis/Hydatidosis considered as one of the most important parasitic diseases in humans and animals across the world. The goal of the present study was to determine a native antigen with an acceptable sensitivity and specificity to be used in the human hydatid cyst diagnostic methods. In the present study, recombinant P29 antigen was used to detect the antibodies in the serum of patients with hydatid cysts of the liver. Read More

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Cystic echinococcosis in slaughtered sheep in Erzurum province, Turkey.

Acta Trop 2022 Jun 7;233:106559. Epub 2022 Jun 7.

Department of Parasitology, Faculty of Veterinary Medicine, Atatürk University, Erzurum 25240, Turkey.

Cystic echinococcosis (CE) is an important zoonotic infection caused by the larval stages of the genus Echinococcus. Turkey is a highly endemic region for CE and the disease is one of the major public health problems. The study was aimed to assess the situation of the CE in sheep in Turkey and also to provide data on circulating genotypes in the country. Read More

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Sudden death due to a massive hydatid pulmonary embolism secondary to a cardiac cyst rupture.

J Forensic Sci 2022 Jun 10. Epub 2022 Jun 10.

Department of Legal Medicine, Trauma and Burn Center, Ben Arous, Tunisia.

Cardiac echinococcosis is rare, and its clinical evolution is slow and asymptomatic until complications occur such as sudden death. Although more frequent in endemic countries, hydatid disease should be known by forensic specialists with regard to the migration flows of people from zones with high endemicity and who are likely to die from infection. We report an autopsy case of a 33-year-old male without any medical history who presented to the emergency room with shortness of breath, chest tightness, tingling all over the body and faintness without fever. Read More

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[Control, elimination, eradication: Where do we stand with NTDs? Scientific day of the SFMTSI, 25 November 2021].

Med Trop Sante Int 2021 12 10;1(4). Epub 2021 Dec 10.

SFMTSI. Hôpital Pitié-Salpêtrière - Pavillon Laveran, 47-83 Boulevard de l'Hôpital, 75651 Paris cedex 13.

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December 2021

Efficacy of Combined Management with Nonsteroidal Anti-inflammatory Drugs for Prevention of Pancreatitis After Endoscopic Retrograde Cholangiography: a Bayesian Network Meta-analysis.

J Gastrointest Surg 2022 Jun 9. Epub 2022 Jun 9.

Graduate School of Qinghai University, Xining, 810000, China.

Objectives: To systematically evaluate the clinical efficacy of rectal nonsteroidal anti-inflammatory drugs (NSAIDs) alone or in combination with other agents for preventing pancreatitis after endoscopic retrograde cholangiopanography.

Methods: We carried out a literature search of random controlled trials (RCTs) on preventing post-operative pancreatitis by administration of the anti-inflammatory drugs, indomethacin and diclofenac, following endoscopic retrograde cholangiopancreatography (ERCP). The databases searched for relevant publications up to July 7, 2021, included PubMed, Cochrane Library, and Embase. Read More

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Expanding the family of Mu-class glutathione transferases in the cestode parasite Echinococcus granulosus sensu lato.

Gene 2022 Jun 6;835:146659. Epub 2022 Jun 6.

Área Inmunología, Departamento de Biociencias, Facultad de Química - Instituto de Higiene, Universidad de la República, Montevideo, Uruguay. Electronic address:

Glutathione transferases (GSTs) perform catalytic and non-catalytic activities, mostly involved in stress-response and cell detoxification. Helminth parasites express several GSTs of multiple classes that are involved in the neutralization of potentially harmful oxidants, and in the inactivation or removal of xenobiotics. Additionally, GSTs participate in immunomodulatory processes that facilitate the parasite establishment and survival within its host. Read More

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Alveolar echinococcosis in a dog in Missouri, USA.

J Vet Diagn Invest 2022 Jun 9:10406387221104754. Epub 2022 Jun 9.

Missouri Orthopaedic Institute.

A 10-y-old, castrated male Boxer dog that was born and had lived in Missouri without any travel history to other states, except for a few trips to Kansas, was presented with a distended abdomen and declined health. Ultrasonographic examination revealed a large hepatic mass, and the dog was euthanized. A postmortem examination revealed that the left liver lobes were largely replaced by a white-to-tan multilobular mass with a cobblestone surface. Read More

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Heart-Shaped lung hydatid cyst in a chest radiograph.

Rev Soc Bras Med Trop 2022 6;55:e0099. Epub 2022 Jun 6.

Department of Thoracic Surgery, Ataturk University, Medical Faculty, Erzurum, Turkey.

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Mediastinal Hydatidosis with an Unusual Presentation: A rare case report.

Sultan Qaboos Univ Med J 2022 May 26;22(2):300-303. Epub 2022 May 26.

Department of Radiodiagnosis, All India Institute of Medical Sciences, Raipur, India.

Hydatidosis is a common zoonotic disease with a high prevalence in developing countries. While a solitary cyst with unilateral lung involvement is common, bilateral involvement and multiple cysts are rare, only seen in 20% and 30% of the cases, respectively. Likewise, extensive involvement of extrapulmonary tissues and mediastinum is rare. Read More

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Immunodiagnosis of cystic echinococcosis in livestock: Development and validation dataset of an ELISA test using a recombinant B8/2 subunit of .

Data Brief 2022 Jun 11;42:108255. Epub 2022 May 11.

London Centre for Neglected Tropical Disease Research and MRC Centre for Global Infectious Disease Analysis, Faculty of Medicine, School of Public Health, Imperial College London, London, UK.

The accuracy of screening tests for detecting cystic echinococcosis (CE) in livestock depends on characteristics of the host-parasite interaction and the extent of serological cross-reactivity with other taeniid species. The AgB8 kDa protein is considered to be the most specific native or recombinant antigen for immunodiagnosis of ovine CE. A particular DNA fragment coding for rAgB8/2 was identified, that provides evidence of specific reaction in the serodiagnosis of metacestode infection. Read More

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Da Vinci Xi surgical system in the robot-assisted laparoscopic pericystectomy plus indocyanine green fluorescence imaging for hepatic cystic echinococcosis.

Asian J Surg 2022 May 31. Epub 2022 May 31.

Department of Hepatobiliary Surgery, People's Hospital of Xinjiang Uygur Autonomous Region, NO.91 Tianchi Road, Urumqi, 830011, China. Electronic address:

Object: The clinical efficacy of robot-assisted laparoscopic pericystectomy using the Da Vinci Xi surgical system plus indocyanine green(ICG) fluorescence imaging and the conventional laparotomy for en bloc pericystectomy was compared.

Methods: The clinical data of 7 patients treated by robot-assisted laparoscopic pericystectomy using the Da Vinci Xi surgical system plus ICG fluorescence imaging at our hospital between October 2019 and July 2021 and 15 patients treated by conventional laparotomy for en bloc pericystectomy were retrospectively analyzed.

Result: Compared with the conventional laparotomy group, the intraoperative blood loss was reduced using the Da Vinci surgical system [(225. Read More

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Risk Factors Associated With Echinococcosis in the General Chinese Population: A Meta-Analysis and Systematic Review.

Front Public Health 2022 17;10:821265. Epub 2022 May 17.

Department of Public Health, Medical College, Qinghai University, Xining, China.

Background: Echinococcosis is a severe zoonotic disease that imposes a substantial burden on human life. This meta-analysis aimed to summarize available data on the prevalence of human echinococcosis and identify the key risk factors for echinococcosis in the Chinese general population.

Methods: Relevant studies were comprehensively searched in the PubMed, EMBASE, Web of Science, Cochrane, Chinese National Knowledge Infrastructure (CNKI), Chongqing VIP Information (VIP), Wanfang and SinoMed databases until August 22, 2020. Read More

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Stability Analysis and Optimal Control Strategies of an Echinococcosis Transmission Model.

Comput Math Methods Med 2022 23;2022:6154866. Epub 2022 May 23.

Faculty of Science and Technology, Sichuan Minzu College, Kangding, China.

This paper presents a deterministic compartmental model for echinococcosis transmission dynamics. The basic reproduction number of the model determines the existence and stability of the disease-free and disease-endemic equilibrium points. We further formulate the optimal control problem and obtain the necessary conditions to minimize the number of infected individuals and the associated costs. Read More

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Corrigendum: Comparison of the Efficacy of Anatomic and Non-anatomic Hepatectomy for Hepatic Alveolar Echinococcosis: Clinical Experience of 240 Cases in a Single Center.

Front Public Health 2022 16;10:917531. Epub 2022 May 16.

Department of Hepatic Hydatidosis, Qinghai Provincial People's Hospital, Xining, China.

[This corrects the article DOI: 10.3389/fpubh.2021. Read More

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A simple score for predicting urinary fistula in patients with renal hydatid cysts.

Libyan J Med 2022 Dec;17(1):2084819

Department of Urology, La Rabta Hospital, University of Tunis El Manar, Tunis, Tunisie.

Hydatid cyst is a major health problem in developing countries. The kidney is in third position of organs affected by hydatid cyst. One of the complications of renal hydatid cyst is a urinary fistula. Read More

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December 2022

Understanding pathogen-host interplay by expression profiles of lncRNA and mRNA in the liver of Echinococcus multilocularis-infected mice.

PLoS Negl Trop Dis 2022 05 31;16(5):e0010435. Epub 2022 May 31.

State Key Laboratory of Veterinary Etiological Biology, National Professional Laboratory for Animal Echinococcosis, Key Laboratory of Veterinary Parasitology of Gansu Province, Key Laboratory of Zoonoses of Agriculture Ministry, Lanzhou Veterinary Research Institute, CAAS, Lanzhou, Gansu, P. R. China.

Almost all Echinococcus multilocularis (Em) infections occur in the liver of the intermediate host, causing a lethal zoonotic helminthic disease, alveolar echinococcosis (AE). However, the long non-coding RNAs (lncRNAs) expression profiles of the host and the potential regulatory function of lncRNA during Em infection are poorly understood. In this study, the profiles of lncRNAs and mRNAs in the liver of mice at different time points after Em infection were explored by microarray. Read More

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