1,004 results match your criteria Eccrine Carcinoma


Concurrent phyllodes tumor, eccrine carcinoma, and multinodular goiter 20 years after radiotherapy for Hodgkin lymphoma.

Clin Case Rep 2018 Dec 6;6(12):2498-2503. Epub 2018 Nov 6.

Division of Surgical Oncology The James Cancer Hospital at The Ohio State University Columbus Ohio.

This unusual case of concurrent eccrine adenocarcinoma, phyllodes tumor, and multinodular goiter serves to alert the oncologic community to the high prevalence of second cancers after childhood radiotherapy. Increased surveillance and index of suspicion are recommended to successfully diagnose and treat second primary cancers in this vulnerable population. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/ccr3.1854
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http://dx.doi.org/10.1002/ccr3.1854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293260PMC
December 2018
5 Reads

Dermoscopy of squamoid eccrine ductal carcinoma: an aid for early diagnosis.

An Bras Dermatol 2018 Nov/Dec;93(6):893-895

Dermatology Service, Hospital do Servidor Público Estadual de São Paulo, São Paulo (SP), Brazil.

Squamoid eccrine ductal carcinoma is a cutaneous malignancy that originates from the eccrine sweat gland. A 76-year-old woman presented with an asymptomatic papule on her nose that had been present for one year. Dermoscopy showed pseudocysts, irregular linear crown vessels, and yellowish-brown globules surrounded by white halos. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
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http://dx.doi.org/10.1590/abd1806-4841.20187307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256200PMC
February 2019
4 Reads

Prognostic factors and survival outcomes for head and neck cutaneous adnexal cancers.

Am J Otolaryngol 2019 Jan - Feb;40(1):110-114. Epub 2018 Sep 22.

Department of Otorhinolaryngology - Head and Neck Surgery, Rush University Medical Center, Chicago, IL, United States of America.

Objectives: Malignant cutaneous adnexal tumors (MCAT) are rare and comprise a heterogeneous group of cancers. There have been several studies reviewing prognostic factors of these tumors, but no studies focusing on the head and neck. This study aimed to review a large population based database to evaluate prognostic factors that could impact survival. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.09.011DOI Listing
September 2018
12 Reads

Mucinous Eccrine Carcinoma of the Sweat Glands: Characteristics, Treatment, and Survival Outcomes of a Rare Malignancy.

Am Surg 2018 Aug;84(8):e307-e308

Conemaugh Memorial Medical Center, Johnstown, Pennsylvania, USA.

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August 2018
6 Reads

Sentinel lymph node biopsy in porocarcinoma: A case reports.

Int J Surg Case Rep 2018 31;53:196-199. Epub 2018 Oct 31.

Department of Surgery, Chirurgia I- Ospedale Policlinico San Martino Genoa, Italy.

Introduction: Eccrine porocarcinoma (EPC) is a slow-growing carcinoma arising from the eccrine sweat glands. Based on its clinical presentation it can be confused with malignant and benign skin lesions, both. Histological examination is essential to formulate a correct diagnosis. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.10.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226587PMC
October 2018
15 Reads

Mucinous Eccrine Carcinoma of the Sweat Glands: Characteristics, Treatment, and Survival Outcomes of a Rare Malignancy.

Am Surg 2018 Aug;84(8):e307-e308

Conemaugh Memorial Medical Center, Johnstown, Pennsylvania, USA.

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Limax Nd:YAG laser-assisted thoracoscopic resection of pulmonary metastases; a single centre's initial experience.

Ir J Med Sci 2018 Oct 31. Epub 2018 Oct 31.

Department of Thoracic Surgery, Mater Misericordiae University Hospital, Eccles St., Dublin, Ireland.

Introduction: Pulmonary metastasectomy and indeed redo-pulmonary metastasectomy are now commonly performed thoracic surgical procedures. The air-sealant, haemostatic, and necrotic properties of the KLS Martin Limax Nd:YAG laser at 1.318 μm make it an ideal tool for limited lung resection such as metastasectomy. Read More

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http://dx.doi.org/10.1007/s11845-018-1924-9DOI Listing
October 2018
2 Reads

Scalp porocarcinoma and lichen planopilaris.

Dermatol Online J 2018 Jul 15;24(7). Epub 2018 Jul 15.

Department of Dermatology and Venereology, Centro Hospitalar Sao Joao, EPE Porto.

Porocarcinoma (PC) is a malignant neoplasm arising from the intraepidermal ductal portion of the sweat gland duct. Lichen planopilaris (LPP) is a not so rare variant of cutaneous lichen planus (LP) with a preferential involvement of hair follicles, consisting of a chronic lymphocytic inflammation, leading to cicatricial alopecia. A 42-year-old woman, recently diagnosed with HIV infection, was referred to our clinic because of an alopecic patch of 6 years' duration. Read More

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July 2018
4 Reads

Dermoscopy of Adnexal Tumors.

Dermatol Clin 2018 Oct 16;36(4):397-412. Epub 2018 Aug 16.

Dermatology Department, Hospital General Universitario de Alicante, ISABIAL, C/Maestro Alonso 109, 03010 Alicante, Spain.

Cutaneous adnexal tumors include lesions with apocrine, eccrine, follicular, sebaceous, and mixed differentiation. Most are benign and sporadic, although malignant forms are occasionally observed and some cases develop in the setting of inherited syndromes. These tumors often cause immense diagnostic difficulty. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07338635183107
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http://dx.doi.org/10.1016/j.det.2018.05.007DOI Listing
October 2018
13 Reads

[Clinicopathologic characterization of malignant mixed tumor of the skin accompanied by eccrine porocarcinoma].

Zhonghua Bing Li Xue Za Zhi 2018 Jul;47(7):536-541

Department of Pathology, the Affiliated Hospital of Qinghai University, Xining 810001, China.

To investigate the clinicopathologic features, immunophenotype, pathological diagnosis and treatment of malignant mixed tumor (MMT). Clinical and pathological features including immunohistochemical phenotypes were analyzed in a case of MMT accompanied with eccrine porocarcinoma (EP) involving both hands, diagnosed definitely in January 2018 along with review of relevant literature. A 64-year-old man presented with multiple rash on both hands for 4 years. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-5807.2018.07.011DOI Listing
July 2018
5 Reads

Squamoid Eccrine Ductal Carcinoma: An Aggressive Mimicker of Squamous Cell Carcinoma.

Am J Dermatopathol 2019 Feb;41(2):140-143

Departments of Dermatology, and.

Squamoid eccrine ductal carcinoma (SEDC) is an uncommon cutaneous adnexal malignancy that has the potential for an aggressive clinical course. The authors present a case of SEDC that resulted in widespread metastases and death. The clinical, histological, and immunohistochemical features of SEDC and several entities on the differential diagnosis are reviewed. Read More

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http://dx.doi.org/10.1097/DAD.0000000000001214DOI Listing
February 2019
13 Reads

Behavior of Cutaneous Adnexal Malignancies: a Single Institution Experience.

Pathol Oncol Res 2018 Jun 14. Epub 2018 Jun 14.

Department of Anatomic Pathology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL, 33612, USA.

Cutaneous adnexal malignancies are biologically and pathologically diverse, and associated with a range of clinical outcomes. Given their rarity, the prognosis and optimal treatment of these neoplasms remains unclear. A single institution database from a tertiary care cancer center of patients treated for malignant cutaneous adnexal tumors was retrospectively analyzed. Read More

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http://dx.doi.org/10.1007/s12253-018-0427-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294697PMC
June 2018
3 Reads

Squamoid eccrine ductal carcinoma.

Cutis 2018 May;101(5):378;380;385

Hartford Dermatology Associates, West Hartford, Connecticut, USA.

Squamoid eccrine ductal carcinoma (SEDC) is an extremely rare cutaneous tumor of unknown etiology. We report the case of a 77-year-old man with a history of treated chronic lymphocytic leukemia along with numerous basal cell and squamous cell carcinomas who presented for evaluation of a 5-cm, stellate, sclerotic plaque on the left chest of approximately 2 years' duration and a suspicious 3-mm pink papule on the right nasal sidewall of 2 months' duration. Initial histology of both lesions revealed carcinoma with squamous and ductal differentiation that extended from the undersurface of the epidermis, favoring a diagnosis of SEDC. Read More

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May 2018
3 Reads

Eccrine Porocarcinoma: New Insights and a Systematic Review of the Literature.

Dermatol Surg 2018 10;44(10):1247-1261

Otolaryngology-Head and Neck Surgery, Keck Medicine of USC, Los Angeles, California.

Background: Eccrine porocarcinoma (EPC) is a rare cutaneous neoplasm with high potential for morbidity and mortality. Due to its rarity, there is a paucity of data profiling diagnosis, work-up, and management.

Objective: To consolidate reported information on demographics, diagnostics, clinical behavior, treatment modalities, and patient outcomes in EPC to provide a reference tool to optimize diagnosis and management. Read More

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http://dx.doi.org/10.1097/DSS.0000000000001566DOI Listing
October 2018

Endocrine mucin-producing sweat gland carcinoma: Clinicopathologic, immunohistochemical, and molecular analysis of 11 cases with emphasis on MYB immunoexpression.

J Cutan Pathol 2018 Jun 7. Epub 2018 Jun 7.

Dermatopathology Friedrichshafen, Friedrichshafen, Germany.

Background: Endocrine mucin-producing sweat gland carcinoma (EMPSGC) is a rare low-grade primary cutaneous sweat gland carcinoma with predilection for the periorbital skin in elderly female patients.

Methods: We describe 11 cases of EMPSGC using a broad panel of immunohistochemical markers including BerEP4, cytokeratin 7, CAM 5.2, synaptophysin, chromogranin, cytokeratin 20, Ki67, progesterone receptor, and estrogen receptor. Read More

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http://dx.doi.org/10.1111/cup.13290DOI Listing
June 2018
4 Reads

Change in Eyelid Carcinoma T Category With Use of the 8th Versus 7th Edition of the American Joint Committee on Cancer: Cancer Staging Manual.

Ophthalmic Plast Reconstr Surg 2019 Jan/Feb;35(1):38-41

Orbital Oncology and Ophthalmic Plastic Surgery, Department of Plastic Surgery.

Purpose: To evaluate the frequency and nature of changes in T category when eyelid carcinomas are staged using the criteria in the 8th edition instead of the 7th edition of the American Joint Committee on Cancer staging manual.

Methods: Following Institutional Review Board approval, a retrospective review was conducted for all consecutive patients with the diagnosis of eyelid carcinoma treated by the senior author from January 2012 through December 2016. After a review of the clinical and pathologic data, each patient's disease was staged using both the 7th-edition and 8th-edition American Joint Committee on Cancer criteria for eyelid carcinomas. Read More

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http://Insights.ovid.com/crossref?an=00002341-900000000-9849
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http://dx.doi.org/10.1097/IOP.0000000000001133DOI Listing
June 2018
8 Reads

Malignant adnexal tumors of the skin: a single institution experience.

World J Surg Oncol 2018 May 30;16(1):99. Epub 2018 May 30.

Department of Surgical Oncology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY, 14263, USA.

Background: Malignant adnexal tumors of the skin (MATS) are rare. We aimed to measure the survival of patients with MATS and identify predictors of improved survival.

Methods: A retrospective review of MATS treated at our institution from 1990 to 2012. Read More

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https://wjso.biomedcentral.com/articles/10.1186/s12957-018-1
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http://dx.doi.org/10.1186/s12957-018-1401-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977488PMC
May 2018
8 Reads
1.200 Impact Factor

Biophysical and photobiological basics of water-filtered infrared-A hyperthermia of superficial tumors.

Int J Hyperthermia 2018 10;35(1):26-36. Epub 2018 May 10.

d Department of Radiation Oncology , Lindenhofspital , Bern , Switzerland.

Thermography-controlled, water-filtered infrared-A (wIRA) is a novel, effective and approved heating technique listed in the ESHO quality assurance guidelines for superficial hyperthermia clinical trials (2017). In order to assess the special features and the potential of wIRA-hyperthermia (wIRA-HT), detailed and updated information about its physical and photobiological background is presented. wIRA allows for (a) application of high irradiances without skin pain and acute grade 2-4 skin toxicities, (b) prolonged, therapeutically relevant exposure times using high irradiances (150-200 mW/cm) and (c) faster and deeper heat extension within tissues. Read More

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https://www.tandfonline.com/doi/full/10.1080/02656736.2018.1
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http://dx.doi.org/10.1080/02656736.2018.1469169DOI Listing
May 2018
5 Reads
2.640 Impact Factor

Scleroderma-like skin changes induced by checkpoint inhibitor therapy.

J Cutan Pathol 2018 Aug 12;45(8):615-618. Epub 2018 Jun 12.

Department of Internal Medicine, University of South Dakota - Sanford School of Medicine, Sioux Falls, South Dakota.

Checkpoint inhibitors have emerged as beneficial therapies in many different types of malignancy. The most common toxicities of checkpoint inhibitors are immune-related adverse events (irAEs). As clinical experience with these agents increases, more irAEs have been described. Read More

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http://doi.wiley.com/10.1111/cup.13273
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http://dx.doi.org/10.1111/cup.13273DOI Listing
August 2018
3 Reads

Primary Mucinous Adenocarcinoma of Skin: Myoepithelial Cells are a Clue to its Diagnosis.

Indian J Dermatol 2018 Mar-Apr;63(2):165-167

Department of Plastic Surgery, Global Hospitals, Hyderabad, Telangana, India.

Primary mucinous adenocarcinoma is a rare adnexal neoplasm of eccrine gland. Fewer than 200 cases are reported in literature. Clinically, it can be mistaken as a benign lesion. Read More

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http://dx.doi.org/10.4103/ijd.IJD_619_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903048PMC

Oral Capecitabine Achieves Response in Metastatic Eccrine Carcinoma.

Case Rep Oncol Med 2018 1;2018:7127048. Epub 2018 Mar 1.

Early Phase Clinical Trial Program, The University of Arizona Cancer Center, 1515 N. Campbell Ave., Tucson, AZ 85724, USA.

The low prevalence rate and limited literature on eccrine carcinoma (EC) pose a challenge to properly diagnosing and treating this rare malignancy. EC lesions tend to present similarly to other cutaneous neoplasms and dermatitis-like conditions. Efficacious treatment guidelines have not been established for patients diagnosed with EC, and few treatment regimens have demonstrated clinical benefit. Read More

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http://dx.doi.org/10.1155/2018/7127048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852884PMC
March 2018
1 Read

Flushing Disorders Associated with Gastrointestinal Symptoms: Part 1, Neuroendocrine Tumors, Mast Cell Disorders and Hyperbasophila.

Clin Med Res 2018 Jun 12;16(1-2):16-28. Epub 2018 Apr 12.

University of Central Florida College of Medicine/HCA Consortium Graduate Medical Education, North Florida Regional Medical Center, 6500 W Newberry Rd, Gainesville, FL 32605.

Flushing is the subjective sensation of warmth accompanied by visible cutaneous erythema occurring throughout the body with a predilection for the face, neck, pinnae, and upper trunk where the skin is thinnest and cutaneous vessels are superficially located and in greatest numbers. Flushing can be present in either a wet or dry form depending upon whether neural-mediated mechanisms are involved. Activation of the sympathetic nervous system results in wet flushing, accompanied by diaphoresis, due to concomitant stimulation of eccrine sweat glands. Read More

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http://dx.doi.org/10.3121/cmr.2017.1379aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108509PMC
June 2018
7 Reads

Primary mucinous carcinoma of skin with a trichoadenomatous component: A rare case report.

Indian J Dermatol Venereol Leprol 2019 Mar-Apr;85(2):171-174

Leelavathi Advanced Skin and Laser Centre, Guntur, Andhra Pradesh, India.

Primary mucinous carcinoma of the skin is a rare subtype of eccrine sweat gland tumors. Differentiating it from metastatic adenocarcinomas is important in the management of this condition. We report the case of a 55-year-old female presenting with a painless nodule, which was subsequently diagnosed as primary mucinous carcinoma of skin with a trichoadenomatous component. Read More

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http://dx.doi.org/10.4103/ijdvl.IJDVL_217_17DOI Listing

Microcystic adnexal carcinoma-diagnostic criteria and therapeutic methods: case report and review of the literature.

Int J Oral Maxillofac Surg 2018 Oct 27;47(10):1258-1262. Epub 2018 Mar 27.

Department of Maxillofacial Surgery, University Hospital Dubrava, Zagreb, Croatia. Electronic address:

Microcystic adnexal carcinoma (MAC) is a rare, infiltrating, locally aggressive cutaneous neoplasm of combined follicular and eccrine/apocrine histogenesis, usually presenting on the upper lip or face. Differentiation from other adnexal tumours is very important because the clinical management of these tumours is radically different, and misdiagnosis may lead to incorrect treatment. A case of recurrent MAC in the upper lip, treated with multiple excisions and postoperative radiation therapy (PORT), is presented herein. Read More

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http://dx.doi.org/10.1016/j.ijom.2018.03.001DOI Listing
October 2018
7 Reads

Aggressive Digital Papillary Adenocarcinoma: Population-Based Analysis of Incidence, Demographics, Treatment, and Outcomes.

Dermatol Surg 2018 07;44(7):911-917

Both authors are affiliated with the Department of Dermatology, Cleveland Clinic Foundation, Cleveland, Ohio.

Background: As a rare cutaneous malignancy, epidemiologic and outcomes data for aggressive digital papillary adenocarcinoma (ADPA) are limited and no treatment guidelines exist.

Objective: To provide a population-based study of ADPA incidence and outcomes with a subgroup comparison of patients with localized versus regional disease.

Methods: Data from 18 registries within the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) program were examined for patients with ADPA (1995-2013) to provide demographic- and cancer-related information, and to calculate race- and age-specific rate ratios, incidence, and mortality. Read More

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http://dx.doi.org/10.1097/DSS.0000000000001483DOI Listing
July 2018
6 Reads

Nodular Cystic Basal Cell Carcinoma of the Trunk: a Diagnostic Dilemma in an Unsuspecting Youth.

Iran J Pathol 2017 1;12(4):410-412. Epub 2017 Oct 1.

Department of Skin and venereal diseases, Dayanand Medical College and Hospital, Ludhiana, India.

Basal cell carcinoma (BCC) commonly affects the elderly and is mostly confined to the head and neck region. Only 10% of all cases occur on the trunk. We presented a case of bullous lesion on the abdomen in a young male, initially diagnosed by clinicians as a vascular nevus. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844689PMC
October 2017
1 Read

A Case of a Malignant Cutaneous Mixed Tumor (Chondroid Syringoma) of the Scapula Treated With Staged Margin-Controlled Excision.

Am J Dermatopathol 2018 Sep;40(9):679-681

Pathology, University of Massachusetts Medical School, Worcester, MA.

Cutaneous mixed tumor (chondroid syringoma) is the cutaneous counterpart of pleomorphic adenoma of salivary glands, comprised of both epithelial and mesenchymal components. Malignant transformation is exceptionally rare, with only a few cases reported. We report a case of a malignant cutaneous mixed tumor in an 86-year-old white man who presented with a pink indurated plaque on his left scapula. Read More

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http://dx.doi.org/10.1097/DAD.0000000000001131DOI Listing
September 2018
21 Reads

Polymorphous Sweat Gland Carcinoma: An Immunohistochemical and Molecular Study.

Am J Dermatopathol 2018 Aug;40(8):580-587

Department of Pathology, Medical College of Wisconsin, Milwaukee, WI.

Polymorphous sweat gland carcinoma is an uncommon low-grade malignant adnexal tumor with a marked predilection for the distal extremities. Histologically, the lesions are characterized by a cellular proliferation showing a combination of growth patterns, including trabecular, solid, tubular, cribriform, or adenoid cystic and pseudopapillary. The immunohistochemical and molecular profile of these tumors has not yet been properly addressed. Read More

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http://dx.doi.org/10.1097/DAD.0000000000001128DOI Listing
August 2018
7 Reads

Once in a Blue Moon … Rare Adnexal Tumor: From the Clinical and Videodermoscopical Aspects to the Mohs Surgery and the Histological Diagnosis.

Open Access Maced J Med Sci 2018 Jan 21;6(1):146-148. Epub 2018 Jan 21.

University G. Marconi of Rome, Dermatology and Venereology, Rome, Italy.

The adnexal tumours are a very heterogeneous group of lesions, more and more studied in the literature. The squamoid eccrine ductal carcinoma (SEDC) is a rare malignant variant that combines ductal structures with squamous differentiation. We report a case of dermoscopic and histological diagnosis of SEDC, treated with Mohs Surgery and with no recurrence of a tumour after 12 months of follow up. Read More

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http://dx.doi.org/10.3889/oamjms.2018.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816288PMC
January 2018
16 Reads

Homeobox transcriptional factor engrailed homeobox 1 is expressed specifically in normal and neoplastic sweat gland cells.

Histopathology 2018 Jun 25;72(7):1199-1208. Epub 2018 Mar 25.

Department of Human Pathology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

Aims: A number of homeobox transcriptional factors are utilised as organ-specific markers in the histopathological diagnosis of neoplasms. We have screened a homeobox gene that is expressed specifically in normal sweat gland cells and is useful for the histopathological diagnosis of sweat gland neoplasms.

Methods And Results: By screening an open database resource of The Human Protein Atlas, 37 genes among the 235 homeobox transcriptional factors were found to be expressed specifically in the skin. Read More

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http://dx.doi.org/10.1111/his.13486DOI Listing
June 2018
13 Reads

Primary Cutaneous Mucinous Carcinoma with Extramammary Paget's Disease: Eccrine or Apocrine?

J Pathol Transl Med 2018 Jul 25;52(4):238-242. Epub 2018 Jan 25.

Department of Pathology, Kosin University Gospel Hospital, Busan, Korea.

Primary cutaneous mucinous carcinoma (PCMC) is an uncommon tumor of the sweat gland origin. The occurrence of PCMC is mostly in middle-aged and older patients, with a slight male predominance. Most cases of PCMC arise on the head, with a preference for eyelids. Read More

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http://dx.doi.org/10.4132/jptm.2017.11.21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056362PMC
July 2018
3 Reads

Microcystic adnexal carcinoma with sebaceous differentiation: Three cases.

J Cutan Pathol 2018 Apr 15;45(4):290-295. Epub 2018 Feb 15.

Private Practice, Friedrischafen, Friedrichshafen Dermatopathologie, Friedrischafen, Germany.

Microcystic adnexal carcinoma (MAC) is a low-grade malignant tumor of the skin. Histologically, this tumor shows a biphasic pattern, with cords and nests of basaloid cells, as well as keratin horn cysts. This biphasic histological appearance has been interpreted by some authors as a sign of double eccrine and folliculosebaceous-apocrine differentiation, whereas some other authors defend a solely eccrine differentiation. Read More

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http://dx.doi.org/10.1111/cup.13109DOI Listing
April 2018
10 Reads

Primary mucinous eccrine carcinoma of the buccal space: A case report and review of the literature.

Am J Otolaryngol 2018 Mar - Apr;39(2):242-246. Epub 2018 Jan 5.

Department of Otolaryngology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

Importance: Mucinous eccrine carcinoma is a rare entity that most commonly affects the head and neck. Due to its low frequency of occurrence, review of its etiology, histopathology, and treatment strategies is beneficial to all clinicians who may encounter similar appearing masses.

Observation: An 84-year-old male presented with a blue mass on the left cheek. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01960709173101
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http://dx.doi.org/10.1016/j.amjoto.2017.12.020DOI Listing
September 2018
5 Reads

Targeted molecular profiling reveals genetic heterogeneity of poromas and porocarcinomas.

Pathology 2018 Apr 18;50(3):327-332. Epub 2017 Dec 18.

Institute of Pathology, University of Heidelberg, Heidelberg, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany. Electronic address:

The genetic landscape of rare benign tumours and their malignant counterparts is still largely unexplored. While recent work showed that mutant HRAS is present in subsets of poromas and porocarcinomas, a more comprehensive genetic view on these rare adnexal neoplasms is lacking. Using high-coverage next generation sequencing, we investigated the mutational profile of 50 cancer-related genes in 12 cases (six poromas and six porocarcinomas). Read More

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http://dx.doi.org/10.1016/j.pathol.2017.10.011DOI Listing
April 2018
45 Reads

A synchronous incidence of eccrine porocarcinoma of the forearm and facial squamous cell carcinoma: A case report.

Int J Surg Case Rep 2018 8;42:116-120. Epub 2017 Dec 8.

Department of Pathology, Sultanah Nur Zahirah Hospital, Jalan Sultan Mahmud, 20400, Kuala Terengganu, Terengganu, Malaysia.

Introduction: Cutaneous appendageal tumor can differentiate towards or arise from either pilosebaceous apparatus or the eccrine sweat glands. Appendageal tumors are relatively rare, their clinical appearance is non-specific, and the vast majority are not diagnosed until after excision. Eccrine porocarcinoma (EP), also known as malignant eccrine poroma is a rare adnexal tumor arising from the intraepithelial ductal parts of the sweat gland. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22102612173064
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http://dx.doi.org/10.1016/j.ijscr.2017.11.066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730414PMC
December 2017
7 Reads

Complete response of a metastatic porocarcinoma treated with paclitaxel, cetuximab and radiotherapy.

Eur J Cancer 2018 02 9;90:142-145. Epub 2017 Dec 9.

Dermatology, Paul Sabatier - Toulouse III University, IUC and CHU de Toulouse, Toulouse, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2017.11.009DOI Listing
February 2018
1 Read

Syringoid Eccrine Carcinoma of the Thigh.

Ann Dermatol 2017 Dec 30;29(6):786-789. Epub 2017 Oct 30.

Department of Dermatology, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Korea.

Syringoid eccrine carcinoma (SEC) is a rare cutaneous malignant tumor thought to be derived from eccrine sweat apparatus. It is usually present in the head, neck and trunk region, and often occurs in the fourth to seventh decades of life. A 94-year-old male patient visited our department with an 80-year history of a lesion showing a 2×2 cm sized well-demarcated round shaped erythematous to pinkish colored nodule with ulcer on his left thigh. Read More

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http://dx.doi.org/10.5021/ad.2017.29.6.786DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705364PMC
December 2017
1 Read

Reticulated acanthoma with sebaceous differentiation mimicking melanoma.

Dermatol Pract Concept 2017 Jul 31;7(3):35-37. Epub 2017 Jul 31.

Department of Dermatology, Mogi das Cruzes University, Mogi das Cruzes, Brazil.

Reticulated acanthoma with sebaceous differentiation (RASD) is a rare, benign cutaneous tumor with peculiar histopathologic characteristics [1]. RASD had been described under various synonyms such as superficial epithelioma with sebaceous differentiation, sebocrine adenoma, poroma with sebaceous differentiation, and seborrheic keratosis with sebaceous differentiation [2]. Clinical differential diagnosis of RASD includes cutaneous superficial epithelial neoplasia such as Bowen's disease, superficial basal cell carcinoma (BCC) and intraepidermal eccrine poroma [1]. Read More

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http://dx.doi.org/10.5826/dpc.0703a07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661163PMC
July 2017
5 Reads

A case of massive porocarcinoma.

Ann R Coll Surg Engl 2017 Nov 15;99(8):e230-e232. Epub 2017 Sep 15.

Children's Surgical Centre , Phnom Penh , Cambodia.

A 53-year-old Cambodian woman presented with nodular masses on the right arm suggestive of a sarcoma-type malignancy. The masses were excised and identified as multiple benign eccrine poromas. The patient re-presented after two years with large relapsed tumours and axillary lymph node involvement. Read More

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http://dx.doi.org/10.1308/rcsann.2017.0153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696933PMC
November 2017
6 Reads

Treatment of Malignant Cutaneous Adnexal Neoplasms.

Actas Dermosifiliogr 2018 Jan - Feb;109(1):6-23. Epub 2017 Oct 6.

Servicio de Dermatología, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, España.

Malignant cutaneous adnexal neoplasms form a group of rare, typically low-grade-malignancy carcinomas with follicular, sebaceous, apocrine, or eccrine differentiation or a combination of the first 3 subtypes. Their clinical presentation is usually unremarkable, and biopsy is required to establish the differentiation subtype and the definitive diagnosis. Due to their rarity, no clear consensus has been reached on which treatment is most effective. Read More

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http://dx.doi.org/10.1016/j.ad.2017.04.005DOI Listing
August 2018
6 Reads

Commentary on Reactive Eccrine Syringofibroadenoma Associated With Basal Cell Carcinoma.

Authors:
Jonathan J Lopez

Dermatol Surg 2018 05;44(5):740-741

Department of Dermatology, Division of Dermatologic Surgery, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1097/DSS.0000000000001320DOI Listing
May 2018
5 Reads

Concomitant poroma and porocarcinoma.

An Bras Dermatol 2017 Jul-Aug;92(4):550-552

Faculty of Medicine, Pontificia Universidad Católica de Chile - Santiago, Chile.

Eccrine poromas and porocarcinomas are adnexal tumors derived from the sweat duct epithelium. However, eccrine poroma is benign in nature, whilst eccrine porocarcinoma is regarded as its malignant counterpart. We report the case of a man who presented simultaneously with an eccrine poroma and eccrine porocarcinoma. Read More

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http://dx.doi.org/10.1590/abd1806-4841.20175719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595608PMC
October 2017
10 Reads

Giant eccrine porocarcinoma in an unusual location.

Indian J Dermatol Venereol Leprol 2018 Jul-Aug;84(4):521

Department of Pathology, Faculty of Medicine, Celal Bayar University, Manisa, Turkey.

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http://dx.doi.org/10.4103/ijdvl.IJDVL_300_16DOI Listing
November 2018
4 Reads

Eccrine Poroma of the Postauricular Area.

Arch Craniofac Surg 2017 Mar 25;18(1):44-45. Epub 2017 Mar 25.

Department of Plastic and Reconstructive Surgery, Dongguk University College of Medicine, Gyeongju, Korea.

Eccrine poroma is a common benign cutaneous tumor that originates in an intraepidermal eccrine duct. This tumor exhibits acral distribution (sole, palm), and is rarely encountered in the head and neck area. In fact eccrine poroma in the postauricular area has only been rarely reported. Read More

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http://dx.doi.org/10.7181/acfs.2017.18.1.44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556742PMC
March 2017
26 Reads

Primary Cutaneous Mucinous Carcinoma of the Eyelid.

Arch Craniofac Surg 2016 Sep 23;17(3):176-179. Epub 2016 Sep 23.

Department of Pathology, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea.

Primary cutaneous mucinous carcinoma (PCMC) is a rare low-grade malignant neoplasm derived from the eccrine glands. PCMC most commonly arises in the head and neck, with the eyelid being the most common site of origin. This case report describes a 51-year-old male with a painless, pigmented superficial nodular lesion over his right lower eyelid. Read More

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http://dx.doi.org/10.7181/acfs.2016.17.3.176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556810PMC
September 2016
12 Reads

Primary Cutaneous Mucinous Carcinoma Treated with Narrow Surgical Margin.

Arch Craniofac Surg 2016 Sep 23;17(3):158-161. Epub 2016 Sep 23.

Department of Plastic and Reconstructive Surgery, Yonsei University Wonju College of Medicine, Wonju, Korea.

Primary cutaneous mucinous carcinoma (PCMC) is a rare malignant tumor of eccrine origin. Clinically, the carcinoma presents as a solitary, slow growing, and painless nodule. For this reason, this tumor is often considered to be a benign mass in the preoperative setting. Read More

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http://dx.doi.org/10.7181/acfs.2016.17.3.158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556805PMC
September 2016
2 Reads

Reactive Eccrine Syringofibroadenoma Associated With Basal Cell Carcinoma: A Histologic Mimicker of Fibroepithelioma of Pinkus.

Dermatol Surg 2018 May;44(5):738-740

Department of Dermatology, University of Texas Medical Branch, Galveston, Texas.

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http://dx.doi.org/10.1097/DSS.0000000000001308DOI Listing
May 2018
13 Reads

Eosinophilic variant of eccrine porocarcinoma of the scalp: Case report and review of the literature.

Int J Womens Dermatol 2017 Sep 14;3(3):157-160. Epub 2017 Jul 14.

Department of Dermatology, University of Connecticut School of Medicine, Farmington, CT.

Porocarcinoma is a rare malignant neoplasm of the acrosyringium with metastatic potential that most commonly presents on the acral skin in older adults (mean age = 72 years). We present the case of a 43-year-old woman who developed a rapidly growing de novo porocarcinoma on the scalp with an unusual oncocytic appearance. The tumor consisted of benign eccrine poroma that arose from the epidermis and broad pushing borders with minimal cytological atypia but ample eosinophilic cytoplasm with numerous mitotic figures. Read More

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http://dx.doi.org/10.1016/j.ijwd.2017.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555270PMC
September 2017
2 Reads

Benign and malignant hybrid adnexal tumors in a patient with epidermodysplasia verruciformis.

J Cutan Pathol 2017 Nov 4;44(11):969-973. Epub 2017 Sep 4.

Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts.

Epidermodysplasia verruciformis (EV) is a genodermatosis characterized by overgrowth of flat warts, pityriasis versicolor-like lesions and an increased propensity for developing cutaneous squamous cell carcinomas due to abnormal susceptibility to infection with beta-human papilloma viruses. Adnexal tumors are not typically associated with EV. Here we report a spectrum of hybrid adnexal tumors with divergent eccrine and folliculosebaceous differentiation, and cytologic features ranging from benign to frankly atypical, in a patient with inherited EV. Read More

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http://dx.doi.org/10.1111/cup.13022DOI Listing
November 2017
5 Reads

Lichen Simplex Chronicus as an Essential Part of the Dermatologic Masquerade.

Open Access Maced J Med Sci 2017 Jul 24;5(4):556-557. Epub 2017 Jul 24.

Department of Dermatology, Venereology and Dermatologic Surgery, Medical Institute of Ministry of Interior, and Onkoderma Polyclinic for Dermatology and Dermatologic Surgery, Sofia, Bulgaria.

A 48 years old female patient had been suffering from the lesions presented for four years. They have started as small, pruritic patches which had been mechanically irritated and grew up in time. The patient had no associated comorbidities or allergies, and she was not under any medication. Read More

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http://dx.doi.org/10.3889/oamjms.2017.133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535688PMC
July 2017
30 Reads