15,255 results match your criteria Eating Disorder Anorexia


Treating eating disorders in the real world - MaiStep: A skill-based universal prevention for schools.

Prev Med 2019 Apr 17. Epub 2019 Apr 17.

Department of Child and Adolescent Psychiatry and Psychotherapy, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131 Mainz, Germany.

Eating disorders are difficult to treat and often associated with morbidity and mortality. Universal prevention approaches are increasingly focusing on enhancing skills, but few eating disorder programs are available for under-15-year-olds. This study aimed to develop and examine a school-based universal prevention program ('MaiStep') for adolescent boys and girls. Read More

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http://dx.doi.org/10.1016/j.ypmed.2019.04.008DOI Listing
April 2019
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The evolution of our understanding and treatment of eating disorders over the past 50 years.

Authors:
Andrea Marks

J Clin Psychol 2019 Apr 20. Epub 2019 Apr 20.

Department of Pediatrics, The Icahn School of Medicine at Mount Sinai, New York, NY.

Although historical descriptions date back to the Hellenistic era, and Gull's naming of anorexia nervosa as a medical disorder to the late 19th century, it is only in the past 50 years that eating disorders have become widely recognized as the prevalent, potentially fatal, complex, and confounding biopsychosocial illnesses we confront today. This paper reviews the considerable advancements in our knowledge of eating disorders during three time periods: the "early years" of the 1960s and 1970s; the "middle years" of the 1980s and 1990s; and the 21st century to date. The recent Diagnostic and Statistical Manual of Mental Disorders, 5th Edition describes six major feeding and eating disorders. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/jclp.22782
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http://dx.doi.org/10.1002/jclp.22782DOI Listing
April 2019
1 Read

Introduction: Novel perspectives on the psychology and psychotherapy of eating disorders.

J Clin Psychol 2019 Apr 17. Epub 2019 Apr 17.

Medical School, Chaim Sheba Medical Center, Tel Hashomer, Israel.

The aim of this introduction to this issue is to review and summarize significant new psychological perspectives and psychotherapeutic interventions in the treatment of eating disorder (EDs). In this issue, five novel therapeutic strategies for the treatment of EDs are presented. These include a combination of psychodynamic psychotherapy and neuropsychology, two recent modifications of cognitive behavioral therapy (the MANTRA, and the conceptualization of change in patients with ED in terms of sense of agency), a specific group movement therapy, and an innovative rehabilitation treatment. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/jclp.22786
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http://dx.doi.org/10.1002/jclp.22786DOI Listing
April 2019
2 Reads

Altered thalamo–cortical and occipital–parietal– temporal–frontal white matter connections in patients with anorexia and bulimia nervosa: a systematic review of diffusion tensor imaging studies

J Psychiatry Neurosci 2019 Apr 17;44(3):1-16. Epub 2019 Apr 17.

From the Department of Neuroscience, Functional Pharmacology, Uppsala University, Uppsala, Sweden (Gaudio, Olivo, Schiöth); the Centre for Integrated Research, Area of Diagnostic Imaging, Universita Campus Bio-Medico di Roma, Rome, Italy (Gaudio); the Department of Physiology and Pharmacology, Neuroimaging Laboratory, Sapienza University, Rome, Italy (Carducci, Piervincenzi); and the Institute for Translational Medicine and Biotechnology, Sechenov First Moscow State Medical University, Moscow, Russia (Schiöth).

Background: Anorexia nervosa and bulimia nervosa are complex mental disorders, and their etiology is still not fully understood. This paper reviews the literature on diffusion tensor imaging studies in patients with anorexia nervosa and bulimia nervosa to explore the usefulness of white matter microstructural analysis in understanding the pathophysiology of eating disorders.

Methods: We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines to identify diffusion tensor imaging studies that compared patients with an eating disorder to control groups. Read More

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http://dx.doi.org/10.1503/jpn.180121DOI Listing
April 2019
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Fat preference and fat intake in individuals with and without anorexia nervosa.

Appetite 2019 Apr 12;139:35-41. Epub 2019 Apr 12.

Department of Psychiatry, Columbia University Irving Medical Center, NY, NY, USA; Department of Psychiatry, New York State Psychiatric Institute, NY, NY, USA.

Fat restriction is a characteristic eating behavior among individuals with anorexia nervosa (AN), and laboratory meal studies demonstrate restricted fat intake among low-weight patients. The Geiselman Food Preference Questionnaire-I (FPQ) is a validated self-report measure that yields a fat preference score (FPS). Prior research reported that patients with AN had a significantly lower FPS than did healthy control (HC) participants. Read More

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http://dx.doi.org/10.1016/j.appet.2019.04.008DOI Listing
April 2019
2 Reads

The Prevalence of Specific Phobia by Age in an Italian Nationwide Survey: How Much Does it Affect the Quality of Life?

Clin Pract Epidemiol Ment Health 2019 20;15:30-37. Epub 2019 Feb 20.

University of Cagliari,Cagliari,Italy.

Introduction: The study aimed to see if a community survey conducted by clinical interviewers with semi-structured psychiatric interviews shows lifetime prevalence rates of Specific Phobia (SP) similar to those found by surveys carried out by lay interviewers and if the high level of impairment found in SP may be confirmed.

Methods: This is a community survey on an Italian nationwide sample randomly selected from registers of municipalities. Tools: semi-structured ANTAS psychiatric interview derived from the SCID-DSM-IV, carried out by clinicians (psychologists or physicians); Short Form Health Survey (SF-12) as a measure of Quality of Life (QoL). Read More

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https://clinical-practice-and-epidemiology-in-mental-health.
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http://dx.doi.org/10.2174/1745017901915010030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407652PMC
February 2019
4 Reads

Negative Body Image Is Not Related to Spontaneous Body-Scaled Motoric Behavior in Undergraduate Women.

Front Psychol 2019 26;10:580. Epub 2019 Mar 26.

Department of Clinical Psychology and Experimental Psychopathology, University of Groningen, Groningen, Netherlands.

Body image disturbance is a core characteristic of anorexia nervosa, which might be grounded in distortions in schematic body representations. In line with this, several studies showed that when walking through door-like apertures of different widths, individuals with anorexia nervosa move as if their bodies are larger than they actually are. They turn their body at a higher aperture/shoulder width ratio than healthy individuals. Read More

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http://dx.doi.org/10.3389/fpsyg.2019.00580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443978PMC
March 2019
1 Read

Early changes in depression predict outcomes of inpatient adolescent anorexia nervosa.

Eat Weight Disord 2019 Apr 8. Epub 2019 Apr 8.

Schneider Children's Medical Center, Petah Tikva, Israel.

Purpose: The aim of this study was to investigate the predictive value of early changes in depression levels during inpatient treatment of adolescent anorexia nervosa (AN).

Methods: Fifty-six adolescents (88% girls) aged 10-18 years (M = 15.35, SD = 2. Read More

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http://dx.doi.org/10.1007/s40519-019-00686-9DOI Listing
April 2019
2 Reads

Micronutrients Deficiencies in 374 Severely Malnourished Anorexia Nervosa Inpatients.

Nutrients 2019 Apr 5;11(4). Epub 2019 Apr 5.

Nutrition Unit, Raymond Poincaré University Hospital (Assistance Publique⁻Hôpitaux de Paris), 92380 Garches, France.

Introduction: Anorexia nervosa (AN) is a complex psychiatric disorder, which can lead to specific somatic complications. Undernutrition is a major diagnostic criteria of AN and it can be associated with several micronutrients deficiencies.

Objectives: This study aimed to determinate the prevalence of micronutrients deficiencies and to compare the differences between the two subtypes of AN (restricting type (AN-R) and binge-eating/purging type (AN-BP)). Read More

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http://dx.doi.org/10.3390/nu11040792DOI Listing
April 2019
2 Reads

Anorexia nervosa: Gut microbiota-immune-brain interactions.

Clin Nutr 2019 Mar 23. Epub 2019 Mar 23.

Institute of Microbiology, Czech Academy of Sciences, Videnska 1083, Prague 4, Czech Republic.

Anorexia nervosa is a psychiatric disorder defined by an extremely low body weight, a devastating fear of weight gain, and body image disturbance, however the etiopathogenesis remains unclear. The objective of the article is to provide a comprehensive review on the potential role of gut microbiota in pathogenesis of anorexia nervosa. Recent advances in sequencing techniques used for microbial detection revealed that this disease is associated with disruption of the composition of normal gut microbiota (dysbiosis), manifested by low microbial diversity and taxonomic differences as compared to healthy individuals. Read More

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http://dx.doi.org/10.1016/j.clnu.2019.03.023DOI Listing
March 2019
4 Reads

Task-sharing interventions for patients with anorexia nervosa or their carers: a systematic evaluation of the literature and meta-analysis of outcomes.

Int Rev Psychiatry 2019 Apr 5:1-15. Epub 2019 Apr 5.

a Section of Eating Disorders, Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience , King's College London , London , UK.

The eating disorder clinical and scientific community advocates for the use of a shared approach to healthcare that actively involves patients and carers. A systematic review of the literature on guided self-help or self-help in anorexia nervosa (targeting either the individual affected by the illness or their carers) and meta-analyses of studies using randomised controlled designs for the evaluation of the outcomes: (1) drop-out from end-of-treatment assessment, (2) body mass index (BMI), (3) anxiety, (4) depression and (5) quality of life, were undertaken. Guided self-help was directed to patients in 15 studies and to carers in seven studies. Read More

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http://dx.doi.org/10.1080/09540261.2019.1588711DOI Listing
April 2019
6 Reads

DSM-5 eating disorder symptoms in adolescents with and without attention-deficit/hyperactivity disorder: A population-based study.

Int J Eat Disord 2019 Apr 4. Epub 2019 Apr 4.

Faculty of Health, Deakin Child Study Centre, School of Psychology, Deakin University, Burwood, Victoria, Australia.

Objective: Attention-deficit/hyperactivity disorder (ADHD) is associated with increased eating disorder symptoms, yet little research examining this association has taken a diagnostic approach using a population-based sample. This cross-sectional study examined differences in DSM-5 eating disorder symptoms and partial-syndrome diagnoses at 14-15 years of age in adolescents with and without ADHD in a population-based sample.

Method: This study uses data from waves 1, 5 and 6 of the Longitudinal Study of Australian Children (N = 2,672). Read More

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http://dx.doi.org/10.1002/eat.23080DOI Listing
April 2019
8 Reads

The perceived therapeutic benefits of complementary medicine in eating disorders.

Complement Ther Med 2019 Apr 31;43:176-180. Epub 2019 Jan 31.

School of Medicine, Western Sydney University, Sydney, Australia; Translational Health Research Institute, Western Sydney University, Sydney, Australia.

Objectives: The purpose of this study was to investigate the perception of Complementary Medicines (CMs) in community women; to identify which CM approaches people perceived as the most beneficial; and the impact of Eating Disorder (ED) symptoms on one's perception of treatment.

Design & Setting: Electronic and paper-based surveys were distributed to a pre-existing cohort of community women (n = 100) aged 18 years and over. The survey included questions about the perception of CMs' benefits in EDs regarding a vignette of a women with Anorexia Nervosa (AN), and whether CMs helped the participant's own personal health. Read More

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http://dx.doi.org/10.1016/j.ctim.2019.01.025DOI Listing
April 2019
2 Reads

Anorexia nervosa is associated with Neuronatin variants.

Psychiatr Genet 2019 Mar 28. Epub 2019 Mar 28.

Clinique des maladies mentales et de l'encéphale, Hôpital Sainte-Anne, Université Paris-Descartes.

Background: Anorexia nervosa is a complex neuropsychiatric disorder presenting with life-threatening low body weight, and a persistent fear of gaining weight. To date, no whole exome sequencing was performed in male individuals with anorexia nervosa.

Aim And Methods: Here, we performed an exome analysis in two independent families with male individuals with anorexia nervosa and found variants in the Neuronatin (NNAT) gene in both probands. Read More

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http://dx.doi.org/10.1097/YPG.0000000000000224DOI Listing
March 2019
2 Reads

Orthorexia Nervosa: Disorder or Not? Opinions of Dutch Health Professionals.

Front Psychol 2019 15;10:555. Epub 2019 Mar 15.

Athena Institute, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.

Orthorexia nervosa (ON) is a condition that is characterized by a pathological obsession with eating foods one considers healthy and has recently been suggested as a new possible diagnosis. However, there is limited published research on health professionals' recognition, ideas and opinions regarding the diagnosis and classification of ON. The aim of this mixed-methods study was to gain insight into the perspectives of clinically active health professionals on ON, and into their opinions on if and how the disorder should be classified. Read More

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http://dx.doi.org/10.3389/fpsyg.2019.00555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428718PMC
March 2019
3 Reads

Increased lipid and lipoprotein concentrations in anorexia nervosa: A systematic review and meta-analysis.

Int J Eat Disord 2019 Mar 28. Epub 2019 Mar 28.

Eating Disorder Unit, Mental Health Center Ballerup, Copenhagen, Denmark.

Objective: Alterations in blood lipid concentrations in anorexia nervosa (AN) has been reported; however, the extent, mechanism, and normalization with weight restoration remain unknown. We conducted a systematic review and a meta-analysis to evaluate changes in lipid concentrations in acutely-ill AN patients compared with healthy controls (HC) and to examine the effect of partial weight restoration.

Method: A systematic literature review and meta-analysis (PROSPERO: CRD42017078014) were conducted for original peer-reviewed articles. Read More

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http://dx.doi.org/10.1002/eat.23051DOI Listing
March 2019
2 Reads

Acipimox Administration With Exercise Induces a Co-feedback Action of the GH, PP, and PYY on Ghrelin Associated With a Reduction of Peripheral Lipolysis in Bulimic and Healthy-Weight Czech Women: A Randomized Study.

Front Endocrinol (Lausanne) 2019 12;10:108. Epub 2019 Mar 12.

Obesity Management Center, Institute of Endocrinology, Prague, Czechia.

Anti-lipolytic drugs and exercise are enhancers of growth hormone (GH) secretion. Decreased circulating free fatty acids (FFA) have been proposed to exert ghrelin-GH feedback loop after administration of an anti-lipolytic longer-acting analog of nicotinic acid, Acipimox (OLB, 5-Methylpyrazine-2-carboxylic acid 4-oxide, molecular weight of 154.1 Da). Read More

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http://dx.doi.org/10.3389/fendo.2019.00108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422902PMC
March 2019
1 Read

Same, same but different: Attention bias for food cues in adults and adolescents with anorexia nervosa.

Int J Eat Disord 2019 Mar 26. Epub 2019 Mar 26.

Section of Eating Disorders, Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.

Objective: Attention processing for food may be biased in people with Anorexia Nervosa (AN). However, previous studies have had inconsistent results. This is likely to be due to indirect assessment of attention, which does not inform on the underlying attention processes, and/or the heterogeneity of participants across studies, testing either adults or adolescents with AN, that is, people at very different developmental and illness stages. Read More

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http://dx.doi.org/10.1002/eat.23064DOI Listing
March 2019
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3.126 Impact Factor

["I remember me..."]

Authors:
Jennifer Coquide

Rev Infirm 2019 Jan;68(247):24-25

45, rue Antoine-Cyreneen-Coutard, 97310 Kourou, France. Electronic address:

Anorexia is a pathology which causes major suffering in those affected by it. Patients and their immediate circle are stakeholders in the care process. Talking about one's hospitalisation and difficult life experience means sharing one's own humanity and passing on the message that eating disorders are not a fatality. Read More

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http://dx.doi.org/10.1016/j.revinf.2018.11.005DOI Listing
January 2019
1 Read

[Eating disorders].

Rev Infirm 2019 Jan;68(247):16-18

Unité spécialisée dans les troubles du comportement alimentaire (TCA), service du Pr Gorwood centre hospitalier Sainte-Anne, 1, rue Cabanis, 75674 Paris, France.

Anorexia and bulimia are part of eating disorders which are defined in the diagnostic and statistical manual as mental health disorders. Screening tools exist and there are different types of treatment which are generally multi-disciplinary. The nurse, as well as the family or immediate circle, are essential players in the care. Read More

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http://dx.doi.org/10.1016/j.revinf.2018.11.002DOI Listing
January 2019
1 Read

Predicting the restrictive eating, exercise, and weight monitoring compulsions of anorexia nervosa.

Eat Weight Disord 2019 Mar 21. Epub 2019 Mar 21.

Centre for Exercise, Nutrition and Health Sciences, School of Policy Studies, University of Bristol, Bristol, BS8 1TZ, UK.

Purpose: Compulsions surrounding restrictive eating, exercise, and weight monitoring are thought to maintain abnormal eating behaviour in individuals with anorexia nervosa (AN). This study aimed to determine if AN psychopathology and trait anxiety explain the presence of restrictive eating, exercise, and weight monitoring compulsions in a mixed sample.

Methods: Participants were 31 females with AN and 31 age and gender-matched healthy individuals (HC). Read More

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http://link.springer.com/10.1007/s40519-019-00674-z
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http://dx.doi.org/10.1007/s40519-019-00674-zDOI Listing
March 2019
3 Reads

Prenatal and perinatal risk factors for eating disorders in women: A population cohort study.

Int J Eat Disord 2019 Mar 20. Epub 2019 Mar 20.

Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Objective: The fetal programming model hypothesizes that developmental programming in utero and in early life induces adaptations that predetermine the adult phenotype. This study investigated whether prenatal/perinatal complications are associated with lifetime eating disorders in women.

Method: Participants included 46,373 adult women enrolled in the Norwegian Mother and Child Cohort Study (den norske Mor & barn-undersøkelsen [MoBa]). Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/eat.23073
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http://dx.doi.org/10.1002/eat.23073DOI Listing
March 2019
3 Reads

Anorexia Nervosa and a Lost Emotional Self: A Psychological Formulation of the Development, Maintenance, and Treatment of Anorexia Nervosa.

Front Psychol 2019 4;10:219. Epub 2019 Mar 4.

Salmons Centre for Applied Psychology, Canterbury Christ Church University, Canterbury, United Kingdom.

In this paper, we argue that Anorexia Nervosa (AN) can be explained as arising from a 'lost sense of emotional self.' We begin by briefly reviewing evidence accumulated to date supporting the consensus that a complex range of genetic, biological, psychological, and socio-environmental risk and maintenance factors contribute to the development and maintenance of AN. We consider how current interventions seek to tackle these factors in psychotherapy and potential limitations. Read More

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http://dx.doi.org/10.3389/fpsyg.2019.00219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410927PMC
March 2019
1 Read

Cognitive and Affective Empathy in Eating Disorders: A Systematic Review and Meta-Analysis.

Front Psychiatry 2019 4;10:102. Epub 2019 Mar 4.

Department of Psychological Medicine, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, United Kingdom.

Recent models of eating disorders (EDs) have proposed social and emotional difficulties as key factors in the development and maintenance of the illness. While a number of studies have demonstrated difficulties in theory of mind and emotion recognition, little is known about empathic abilities in those with EDs. Further, few studies have examined the cognitive-affective empathy profile in EDs. Read More

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http://dx.doi.org/10.3389/fpsyt.2019.00102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410675PMC
March 2019
2 Reads

Characteristics and content of intrusive images in patients with eating disorders.

Eur Eat Disord Rev 2019 Mar 18. Epub 2019 Mar 18.

Faculty of Psychology and Educational Sciences, KU Leuven, Tiensestraat 102, 300 Leuven, Belgium.

The aim of this study was to examine the characteristics and content of intrusive images in patients with different subtypes of eating disorders (EDs). Data were collected from 74 ED patients, 22 dieting, and 29 nondieting controls. Participants completed a set of self-report questionnaires. Read More

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http://dx.doi.org/10.1002/erv.2671DOI Listing
March 2019
1 Read

The classification of eating disorders in China: A categorical model or a dimensional model.

Int J Eat Disord 2019 Mar 18. Epub 2019 Mar 18.

Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Objective: According to the ICD-10 and DSM-5, eating disorders (EDs) are classified using a categorical model that assumes the subtypes are qualitatively different from one another. However, it is still intensely debated that a dimensional model is more suitable. The aim of this study is to examine whether EDs have a categorical or dimensional latent structure using a sample of Chinese ED patients. Read More

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http://dx.doi.org/10.1002/eat.23069DOI Listing
March 2019
1 Read
3.126 Impact Factor

An update on the medical consequences of anorexia nervosa.

Curr Opin Pediatr 2019 Mar 14. Epub 2019 Mar 14.

GMCCLINICS and Medical Department of the Eating Disorder Unit at The American Centre of Psychiatry and Neurology ACPN, Dubai, United Arab Emirates.

Purpose Of Review: The diagnosis of anorexia nervosa is associated with the highest mortality rate of any psychiatric disorder, mainly caused by medical complications.The purpose of this article is to review the common medical consequences of anorexia nervosa focusing on the special considerations related to children and adolescents and recent updates on the pathophysiology of these complications and their prognosis significance.

Recent Findings: The main findings were related to the diagnostic and prognostic value of hypokalaemia, QTc prolongation, hypoglycaemia and orthostatic changes. Read More

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http://dx.doi.org/10.1097/MOP.0000000000000755DOI Listing
March 2019
5 Reads

The effect of intranasal oxytocin on the perception of affective touch and multisensory integration in anorexia nervosa: protocol for a double-blind placebo-controlled crossover study.

BMJ Open 2019 Mar 15;9(3):e024913. Epub 2019 Mar 15.

Department of Clinical, Educational and Health Psychology, University College London, London, UK.

Introduction: Anorexia nervosa (AN) is an eating disorder characterised by restriction of energy intake, fears of gaining weight and related body image disturbances. The oxytocinergic system has been proposed as a pathophysiological candidate for AN. Oxytocin is a neuropeptide involved in bodily processes (eg, breast feeding) and in the onset of social behaviours (eg, bonding). Read More

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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2018-02491
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http://dx.doi.org/10.1136/bmjopen-2018-024913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429868PMC
March 2019
3 Reads

Dental and periodontal health in adults with eating disorders: A case-control study.

J Dent 2019 Mar 12. Epub 2019 Mar 12.

Department of Periodontology, Odontology Unit, AP-HP, GH Paris-Est, Rothschild Hospital, Paris, France; UFR of Odontology, University of Paris Diderot, 5 rue Garancière, Paris, France; Laboratory Orofacial Pathologies, Imaging and Biotherapies, EA 2496, Dental School, University of Paris Descartes, 1 rue Maurice Arnoux, 92120 Paris, France. Electronic address:

Objectives: This study evaluates dental and periodontal health in anorexia nervosa and bulimia nervosa patients.

Methods: Seventy females with eating disorders (36 anorexia nervosa) attending a public hospital Psychiatry and Addiction unit were compared with age-matched controls (n = 70). Full-mouth examination and oral hygiene behaviours were recorded for all participants. Read More

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http://dx.doi.org/10.1016/j.jdent.2019.03.005DOI Listing
March 2019
1 Read

Facets of shared decision-making on drug treatment for adults with an eating disorder.

Int Rev Psychiatry 2019 Mar 14:1-15. Epub 2019 Mar 14.

a South London and Maudsley NHS Foundation Trust , Bethlem Royal Hospital , London , UK.

Shared decision-making (SDM) means that clinicians and the patient make decisions about the treatment together. Regarding drug treatment in eating disorders (EDs), such decisions may include psychopharmacological treatment for the ED itself, medications for potential co-morbid psychiatric disorders, pharmacological strategies to alleviate the health consequences of an ED, or 'pro re nata' (PRN) medication which is given in acute care when required. Decisions regarding drug treatment in EDs should be specific in terms of the active pharmacological substance, its dose, its route of administration, and the duration of treatment. Read More

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http://dx.doi.org/10.1080/09540261.2019.1571995DOI Listing
March 2019
4 Reads

Reducing anorexia nervosa stigma: an exploration of a social consensus intervention and the moderating effect of blameworthy attributions.

J Ment Health 2019 Mar 12:1-7. Epub 2019 Mar 12.

b Faculty of Health , Centre for Applied Psychology, University of Canberra , Canberra , Australia.

Background: Research suggests that blameworthy attributions towards individuals with anorexia nervosa are common, which in turn elicit more stigmatising attitudes towards those with the disorder. The social consensus approach has been found to reduce stigmatising attitudes in various domains and, as such, is a promising avenue to pursue for ameliorating stigma in anorexia nervosa.

Aims: The present study primarily sought to investigate the effectiveness of a social consensus approach in reducing stigma towards individuals with anorexia nervosa. Read More

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http://dx.doi.org/10.1080/09638237.2019.1581326DOI Listing
March 2019
1 Read

A lateral hypothalamus to basal forebrain neurocircuit promotes feeding by suppressing responses to anxiogenic environmental cues.

Sci Adv 2019 Mar 6;5(3):eaav1640. Epub 2019 Mar 6.

Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, UTHealth McGovern Medical School, 7000 Fannin St., Houston, TX 77030, USA.

Animals must consider competing information before deciding to eat: internal signals indicating the desirability of food and external signals indicating the risk involved in eating within a particular environment. The behaviors driven by the former are manifestations of hunger, and the latter, anxiety. The connection between pathologic anxiety and reduced eating in conditions like typical depression and anorexia is well known. Read More

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http://dx.doi.org/10.1126/sciadv.aav1640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402846PMC
March 2019
1 Read

White matter alterations in anorexia nervosa: Evidence from a voxel-based meta-analysis.

Neurosci Biobehav Rev 2019 May 6;100:285-295. Epub 2019 Mar 6.

UCL Great Ormond Street Institute of Child Health, London, UK; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, USA; Department of Psychiatry, University of Geneva, Geneva, Switzerland. Electronic address:

Anorexia nervosa (AN) is a severe psychiatric disorder with a complex and poorly understood etiology. Recent studies have sought to investigate differences in white matter microstructure in AN, with significant results in several brain regions. A systematic literature search of Embase, PubMed and Psychinfo databases was conducted in order to identify Diffusion Tensor Imaging (DTI) studies of patients with AN and controls. Read More

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http://dx.doi.org/10.1016/j.neubiorev.2019.03.002DOI Listing
May 2019
4 Reads

[Female adolescents with eating disordes: cardiac abnormalities].

Rev Med Chil 2019 ;147(1):47-52

Clínica Alemana de Santiago, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago, Chile.

Background: Cardiovascular complications can occur in up to 80% of adolescent patients with eating disorders (ED) and account for 30% of their mortality.

Aim: To evaluate cardiovascular complications in adolescents with ED and their evolution after refeeding.

Patients And Methods: In adolescents with ED admitted to treatment, we assessed the nutritional status, weight loss prior to consultation, presence of bradycardia (BC, defined as heart rate < 60 bpm), we performed an electrocardiogram (ECG) and an echocardiography and measured thyroid hormones. Read More

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http://dx.doi.org/10.4067/S0034-98872019000100047DOI Listing
March 2019
7 Reads

Pathways to specialist care for eating disorders: An Italian multicentre study.

Eur Eat Disord Rev 2019 May 7;27(3):274-282. Epub 2019 Mar 7.

Department of Mental Health, University of Campania "L. Vanvitelli", Naples, Italy.

Two hundred forty six patients with eating disorders (EDs) recruited from eight Italian specialized treatment centres were administered with the World Health Organization "Encounter Form," a standardized schedule that makes it possible to characterize the clinical pathways that patients follow to reach specialized care. The median time from symptoms onset to specialized care was 114 weeks. Primary "points of access to care" were general practitioners (25%), psychiatrists (18%), and clinical nutritionists (17%), followed by various other carers. Read More

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http://dx.doi.org/10.1002/erv.2669DOI Listing
May 2019
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Clinical management of females seeking fertility treatment and of pregnant females with eating disorders.

Eur Eat Disord Rev 2019 May 7;27(3):215-223. Epub 2019 Mar 7.

Department of Psychosomatic Medicine and Psychotherapy, Hannover Medical School, Hanover, Germany.

The presence of eating disorders (EDs) might have a significant impact upon pregnancy, birth, and the offspring's well-being. Thus, several specific aspects are to be considered by medical professionals when females with EDs either become pregnant or intend to undergo fertility treatment. Clinical management algorithms for gynaecologists and fertility specialists are missing. Read More

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http://dx.doi.org/10.1002/erv.2667DOI Listing
May 2019
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Diagnostic, clinical, and personality correlates of food anxiety during a food exposure in patients diagnosed with an eating disorder.

Eat Weight Disord 2019 Mar 7. Epub 2019 Mar 7.

Department of Psychiatry, Washington University, St. Louis, MO, USA.

Background: Eating disorders are characterized by high levels of anxiety, especially while eating. However, little is known about anxiety experienced during meals and specifically what other variables may impact such anxiety.

Objective: We sought to further quantify and understand the relationship between food anxiety, eating disorders, and related correlates (e. Read More

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http://dx.doi.org/10.1007/s40519-019-00669-wDOI Listing
March 2019
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Cortical thickness 20 years after diagnosis of anorexia nervosa during adolescence.

Eur Arch Psychiatry Clin Neurosci 2019 Mar 7. Epub 2019 Mar 7.

Magnetic Resonance Image Core Facility, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

Objective: The objective of the present study is to evaluate cortical thickness (CT) abnormalities using FreeSurfer in adult subjects who had an onset of anorexia nervosa during their adolescence some 20 years previously, and to compare them with control subjects.

Methods: Fifty-four participants, including 26 women who were diagnosed and treated for AN during adolescence some 20 years previously and 28 healthy women of similar age and geographical area were assessed using structured interviews and MRI scans. Prior AN subjects were divided into two groups depending on their current eating disorder status (recovered or not recovered from any eating disorder). Read More

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http://dx.doi.org/10.1007/s00406-019-00992-4DOI Listing
March 2019
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Decline of Plasma Concentrations of Interleukin-18 in Severely Malnourished Patients with Anorexia Nervosa: Exploratory Analysis.

Nutrients 2019 Mar 3;11(3). Epub 2019 Mar 3.

Department of Psychiatry, Nagoya University Hospital, Nagoya 466-8560, Japan.

Multiple studies on the dynamics of inflammatory cytokines in patients with anorexia nervosa (AN) have been published, although results are not consistent among reports. Thus the pathophysiologic roles of these cytokines are not clear. We performed an exploratory analysis that included (1) comparisons of plasma interleukin-18 (IL-18) concentrations between patients with AN ( = 21) and healthy controls ( = 39), and (2) correlations between body mass index (BMI) and IL-18 concentrations in both groups, exploring the relationship between malnourishment and IL-18. Read More

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http://dx.doi.org/10.3390/nu11030540DOI Listing
March 2019
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Optimizing treatment outcomes in adolescents with eating disorders: The potential role of cognitive behavioral therapy.

Int J Eat Disord 2019 Mar 4. Epub 2019 Mar 4.

Department of Psychology, University of Sheffield, Sheffield, United Kingdom.

Objective: While family-based treatment (FBT) is the leading psychological therapy for adolescents with eating disorders, it is not universally effective or suitable. This study considered the effectiveness of cognitive-behavioral therapy for eating disorders (CBT-ED) in adolescent cases where FBT was not fully effective or where it was not applicable to the individual case.

Method: A transdiagnostic case series of 54 adolescents with eating disorders (52% with anorexia nervosa; 31% with atypical anorexia nervosa) were offered CBT-ED following previous treatment using FBT or following FBT being judged inappropriate. Read More

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http://dx.doi.org/10.1002/eat.23067DOI Listing
March 2019
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Medication in AN: A Multidisciplinary Overview of Meta-Analyses and Systematic Reviews.

J Clin Med 2019 Feb 25;8(2). Epub 2019 Feb 25.

French Federation Anorexia Bulimia (FFAB), 75014 Paris, France.

Drugs are widely prescribed for anorexia nervosa in the nutritional, somatic, and psychiatric fields. There is no systematic overview in the literature, which simultaneously covers all these types of medication. The main aims of this paper are (1) to offer clinicians an overview of the evidence-based data in the literature concerning the medication (psychotropic drugs and medication for somatic and nutritional complications) in the field of anorexia nervosa since the 1960s, (2) to draw practical conclusions for everyday practise and future research. Read More

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http://dx.doi.org/10.3390/jcm8020278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406645PMC
February 2019
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Same behaviours, different reasons: what do patients with co-occurring anorexia and autism want from treatment?

Int Rev Psychiatry 2019 Mar 1:1-10. Epub 2019 Mar 1.

a Institute of Psychiatry, Psychology and Neuroscience, Department of Psychological Medicine , King's College London , London , UK.

Research suggests that up to one in four individuals with anorexia nervosa (AN) may be on the autistic spectrum, and that these autistic traits may not have been recognized or diagnosed prior to eating disorder (ED) treatment. Significantly, these heightened autistic traits are associated with poorer treatment outcomes, suggesting that treatment may need to be adapted for this population. The purpose of this study was to explore with people with AN on the autistic spectrum their experiences of ED treatment, and their views on what needs to be changed. Read More

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http://dx.doi.org/10.1080/09540261.2018.1531831DOI Listing
March 2019
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Long-term Outcomes of Adolescent Anorexia Nervosa on Bone.

J Adolesc Health 2019 Mar 11;64(3):305-310. Epub 2018 Dec 11.

Department of Endocrinology, The Children's Hospital at Westmead, Westmead, New South Wales, Australia; Discipline of Paediatrics & Child Health, University of Sydney, Sydney, New South Wales, Australia. Electronic address:

Purpose: Anorexia nervosa (AN) is a chronic and life-threatening eating disorder that can have a considerable negative impact on the growing skeleton. We hypothesized that the long-term impact on bone health may persist even after normalization of body weight.

Methods: 41 females (mean age 21. Read More

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http://dx.doi.org/10.1016/j.jadohealth.2018.07.025DOI Listing
March 2019
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Bone mineral density and estimated hip strength in men with anorexia nervosa, atypical anorexia nervosa and avoidant/restrictive food intake disorder.

Clin Endocrinol (Oxf) 2019 Feb 28. Epub 2019 Feb 28.

Neuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts.

Objective: Few bone mineral density (BMD) data are available in men with anorexia nervosa (AN), and none in those with atypical AN (ATYP) (AN psychological symptoms without low weight) or avoidant/restrictive food intake disorder (ARFID) (restrictive eating without AN psychological symptoms). We investigated the prevalence and determinants of low BMD and estimated hip strength in men with these disorders.

Design: Cross-sectional: two centres. Read More

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http://dx.doi.org/10.1111/cen.13960DOI Listing
February 2019
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A Web-Based Intervention (MotivATE) to Increase Attendance at an Eating Disorder Service Assessment Appointment: Zelen Randomized Controlled Trial.

J Med Internet Res 2019 Feb 27;21(2):e11874. Epub 2019 Feb 27.

Research Centre for Behaviour Change, Psychology Department, Bournemouth University, Poole, United Kingdom.

Background: Early assessment and treatment of eating disorder patients is important for patient outcomes. However, up to a third of people referred for treatment do not access services and 16.4% do not attend their first scheduled assessment appointment. Read More

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http://dx.doi.org/10.2196/11874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414822PMC
February 2019
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"We don't really know what else we can do": Parent experiences when adolescent distress persists after the Maudsley and family-based therapies for anorexia nervosa.

J Eat Disord 2019 12;7. Epub 2019 Feb 12.

Western Sydney University, Locked Bag 1797, Penrith, 2751 Australia.

Background: Maudsley Family Therapy (MFT), and its manualised version, Family-Based Therapy (FBT), are the only well-established treatment interventions for adolescent anorexia nervosa (AN), with treatment efficacy primarily measured by improvements in eating behaviours and weight restoration. A crucial component of this therapy is an intensive home-based refeeding intervention that requires a substantial commitment from parents for up to one year. While this treatment works to restore weight in a proportion of adolescents, very little is known about its impacts on family distress, relationships and identity, including in the 40% of families where the adolescent experiences ongoing eating disorder (ED) symptomatology and/or psychological distress during and post-treatment. Read More

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http://dx.doi.org/10.1186/s40337-019-0235-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373134PMC
February 2019
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The Mouse - A Valuable Resource in Anorexia Nervosa Research.

Authors:
Ida A K Nilsson

Front Neurosci 2019 5;13:59. Epub 2019 Feb 5.

Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.

Animal models are invaluable resources in research concerning the neurobiology of anorexia nervosa (AN), to a large extent since valid clinical samples are rare. None of the existing models can capture all aspects of AN but they are able to mirror the core features of the disorder e.g. Read More

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https://www.frontiersin.org/article/10.3389/fnins.2019.00059
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http://dx.doi.org/10.3389/fnins.2019.00059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370726PMC
February 2019
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Genetic risk factors for eating disorders: an update and insights into pathophysiology.

Ther Adv Psychopharmacol 2019 12;9:2045125318814734. Epub 2019 Feb 12.

Department of Psychological Medicine, King's College London, London, UK.

Genome-wide-association studies (GWASs), epigenetic, gene-expression and gene-gene interaction projects, nutritional genomics and investigations of the gut microbiota have increased our knowledge of the pathophysiology of eating disorders (EDs). However, compared with anorexia nervosa, genetic studies in patients with bulimia nervosa and binge-eating disorder are relatively scarce, with the exception of a few formal genetic and small-sized candidate-gene-association studies. In this article, we review important findings derived from formal and molecular genetics in order to outline a genetics-based pathophysiological model of EDs. Read More

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http://dx.doi.org/10.1177/2045125318814734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378634PMC
February 2019
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Applying the disgust conditioning model of food avoidance: A case study of acceptance-based interoceptive exposure.

Int J Eat Disord 2019 Apr 22;52(4):473-477. Epub 2019 Feb 22.

Eating and Weight Disorders Program, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York.

Objective: The current case report details the treatment of a 16-year-old adolescent with anorexia nervosa utilizing a novel adjunct, acceptance-based interoceptive exposure, prior to family-based treatment (FBT) for eating disorders.

Method: The exposure-based module focused particularly on the tolerance of disgust. For six sessions, the clinician taught the client skills that could be used to tolerate distress to visceral sensations associated with disgust. Read More

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http://dx.doi.org/10.1002/eat.23045DOI Listing
April 2019
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Introduction to a special issue on child and adolescent feeding and eating disorders and avoidant/restrictive food intake disorder.

Int J Eat Disord 2019 Apr 22;52(4):327-330. Epub 2019 Feb 22.

Eating Disorders Clinical and Research Program, Massachusetts General Hospital, Boston, Massachusetts.

Objective: We are very pleased to introduce a special issue of the International Journal of Eating Disorders on child and adolescent feeding and eating disorders and avoidant/restrictive food intake disorder (ARFID).

Method: Contributions focused on five main themes: (1) the definition and assessment of ARFID; (2) the clinical phenomenology of ARFID; (3) similarities and differences between ARFID and anorexia nervosa (AN); (4) novel treatments for ARFID; and (5) new ideas for improving treatment outcomes in AN.

Results: These papers highlight the importance of clear operationalization and measurement of the ARFID diagnostic criteria. Read More

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http://dx.doi.org/10.1002/eat.23052DOI Listing
April 2019
9 Reads