3,419 results match your criteria EEG in Brain Tumors


Stereotactic radiofrequency thermocoagulation and resective surgery for patients with hypothalamic hamartoma.

J Neurosurg 2020 Apr 17:1-8. Epub 2020 Apr 17.

Departments of1Neurosurgery and.

Objective: In this study, the authors compared the efficacy and safety of stereotactic radiofrequency thermocoagulation (SRT) and resective surgery (RS) for patients with hypothalamic hamartoma (HH).

Methods: The authors included all patients with HHs who were treated by SRT or hamartoma resection. Seizure outcomes were assessed by blinded observers according to the International League Against Epilepsy (ILAE) classification. Read More

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http://dx.doi.org/10.3171/2020.2.JNS193423DOI Listing

[Surgical treatment of epilepsy in children with gloneuronal brain tumors: morphology, MRI semiology and factors affecting the outcome].

Zh Vopr Neirokhir Im N N Burdenko 2020 ;84(1):6-22

Burdenko Neurosurgical Center, Moscow, Russia.

Introduction: Glioneuronal tumors (GNT) are usually found in children (less than 1.5% of all neoplasms of the brain). With rare exceptions, they are benign and usually manifest only by epilepsy, which is quite often resistant to treatment with AE drugs. Read More

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http://dx.doi.org/10.17116/neiro2020840116DOI Listing
January 2020

Mapping cognitive and emotional networks in neurosurgical patients using resting-state functional magnetic resonance imaging.

Neurosurg Focus 2020 02;48(2):E9

Departments of1Neurosurgery and.

Neurosurgery has been at the forefront of a paradigm shift from a localizationist perspective to a network-based approach to brain mapping. Over the last 2 decades, we have seen dramatic improvements in the way we can image the human brain and noninvasively estimate the location of critical functional networks. In certain patients with brain tumors and epilepsy, intraoperative electrical stimulation has revealed direct links between these networks and their function. Read More

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http://dx.doi.org/10.3171/2019.11.FOCUS19773DOI Listing
February 2020

Surgery of the amygdala and uncus: a case series of glioneuronal tumors.

Acta Neurochir (Wien) 2020 Apr 30;162(4):795-801. Epub 2020 Jan 30.

Department of Neurosurgery, Medical College of Georgia, Augusta University, 1120 15th Street, BI 3088, Augusta, GA, 30912, USA.

Background: Patients with a lesion within the amygdala and uncus may develop temporal lobe epilepsy despite having functional mesial structures. Resection of functional hippocampus and surrounding structures may lead to unacceptable iatrogenic deficits. To our knowledge, there is limited descriptions of surgical techniques for selectively resecting the amygdala and uncus lesions while preserving the hippocampus in patients with language-dominant temporal lobe pathology. Read More

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http://dx.doi.org/10.1007/s00701-020-04249-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066292PMC

Seizures in Patients With Metastatic Brain Tumors: Prevalence, Clinical Characteristics, and Features on EEG.

J Clin Neurophysiol 2019 Dec 17. Epub 2019 Dec 17.

Hollings Cancer Center, Charleston, South Carolina, U.S.A.

Introduction: Metastases to the brain (MB) occur in up to 30% of adults with cancer; of these, 15% to 35% may have seizures. We investigated clinical and pathologic associations with seizure and EEG findings in patients with MB, given the sparse literature in this area.

Methods: We performed a retrospective chart review of adults with pathologically confirmed MB treated at a large tertiary care center between April 8, 2006, and December 14, 2018. Read More

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http://dx.doi.org/10.1097/WNP.0000000000000671DOI Listing
December 2019

Clinical utility of arterial spin labeling imaging in disorders of the nervous system.

Neurosurg Focus 2019 12;47(6):E5

Neuroimaging is an indispensable tool in the workup and management of patients with neurological disorders. Arterial spin labeling (ASL) is an imaging modality that permits the examination of blood flow and perfusion without the need for contrast injection. Noninvasive in nature, ASL provides a feasible alternative to existing vascular imaging techniques, including angiography and perfusion imaging. Read More

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http://dx.doi.org/10.3171/2019.9.FOCUS19567DOI Listing
December 2019

A case of dyskinesia after levetiracetam administration.

BMC Neurol 2019 Nov 18;19(1):292. Epub 2019 Nov 18.

Department of Neurology, Epilepsy Research Institute, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, Korea.

Background: Antiepileptic drug (AED) induced dyskinesia is an unusual manifestation in the medical field. In the previous case reports describing first generation-AED related involuntary movements, the authors suggested that a plausible cause is pharmacokinetic interactions between two or more AEDs. To date, development of dyskinesia after levetiracetam (LEV) has not been reported. Read More

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http://dx.doi.org/10.1186/s12883-019-1519-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862831PMC
November 2019

Permutation entropy in intraoperative ECoG of brain tumour patients in awake tumour surgery- a robust parameter to separate consciousness from unconsciousness.

Sci Rep 2019 11 11;9(1):16482. Epub 2019 Nov 11.

Department of Neurosurgery, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.

Awake craniotomies represent an essential opportunity in the case of lesions in eloquent areas. Thus, optimal surveillance of the patient during different stages of sedation, as well as the detection of seizure activity during brain surgery, remains difficult, as skin electrodes for electroencephalographic (EEG) analysis are not applicable in most cases. We assessed the applicability of ECoG to monitor different stages of sedation, as well as the influence of different patient characteristics, such as tumour volume, size, entity, and age or gender on permutation entropy (PeEn). Read More

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http://dx.doi.org/10.1038/s41598-019-52949-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848144PMC
November 2019

Presurgical epilepsy evaluation and epilepsy surgery.

F1000Res 2019 29;8. Epub 2019 Oct 29.

Department of Neurology, General Hospital Hietzing with Neurological Center Rosenhügel, Vienna, Austria.

With a prevalence of 0.8 to 1.2%, epilepsy represents one of the most frequent chronic neurological disorders; 30 to 40% of patients suffer from drug-resistant epilepsy (that is, seizures cannot be controlled adequately with antiepileptic drugs). Read More

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http://dx.doi.org/10.12688/f1000research.17714.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820825PMC
October 2019

Operculoinsular cortectomy for refractory epilepsy. Part 1: Is it effective?

J Neurosurg 2019 Sep 20:1-10. Epub 2019 Sep 20.

2Neurology, and.

Objective: Patients with refractory epilepsy of operculoinsular origin are often denied potentially effective surgical treatment with operculoinsular cortectomy (also termed operculoinsulectomy) because of feared complications and the paucity of surgical series with a significant number of cases documenting seizure control outcome. The goal of this study was to document seizure control outcome after operculoinsular cortectomy in a group of patients investigated and treated by an epilepsy team with 20 years of experience with this specific technique.

Methods: Clinical, imaging, surgical, and seizure control outcome data of all patients who underwent surgery for refractory epilepsy requiring an operculoinsular cortectomy were retrospectively reviewed. Read More

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http://dx.doi.org/10.3171/2019.4.JNS1912DOI Listing
September 2019
1 Read
3.737 Impact Factor

Paraneoplastic opsoclonus-myoclonus syndrome secondary to melanoma metastasis form occult primary cancer.

Case Rep Neurol 2019 Jan-Apr;11(1):66-79. Epub 2019 Feb 28.

Department of Critical Care, Hospital General León, León de los Aldama, Mexico.

Introduction: Opsoclonus-myoclonus syndrome (OMS) is an inflammatory neurological disorder, often requiring a prompt medical evaluation. Among the diverse etiologies associated with OMS are autoimmune, infectious, paraneoplastic, and systemic diseases, and drug intoxication.

Clinical Summary: The case of a 36-year-old female with a disabling holocranial headache, sudden loss of consciousness, aggressive behavior, vertigo, and a personal history of somatoform disorder and major depression is presented here. Read More

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http://dx.doi.org/10.1159/000497034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739717PMC
February 2019
2 Reads

Polymorphous Low-Grade Neuroepithelial Tumor of the Young: A Case Report with Genomic Findings.

World Neurosurg 2019 Dec 11;132:347-355. Epub 2019 Sep 11.

Department of Pathology, Medical College of Georgia at Augusta University, Augusta, Georgia, USA. Electronic address:

Background: Polymorphous low-grade neuroepithelial tumor of the young (PLNTY) is a recently recognized epileptogenic neuroepithelial tumor. Despite its distinctiveness, its polymorphous histology and the nature of its oligodendrocyte-like cells remain unclear.

Case Description: A 30-year-old, right-handed man was diagnosed with intractable epilepsy since 22 years of age. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.08.221DOI Listing
December 2019
17 Reads
2.417 Impact Factor

Management of Childhood Headache in the Emergency Department. Review of the Literature.

Front Neurol 2019 23;10:886. Epub 2019 Aug 23.

Chair of Pediatrics, NESMOS Department, Faculty of Medicine and Psychology, Sapienza University, Sant' Andrea Hospital, Rome, Italy.

Headache is the third cause of visits to pediatric emergency departments (ED). According to a systematic review, headaches in children evaluated in the ED are primarily due to benign conditions that tend to be self-limiting or resolve with appropriate pharmacological treatment. The more frequent causes of non-traumatic headache in the ED include primitive headaches (21. Read More

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http://dx.doi.org/10.3389/fneur.2019.00886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716213PMC
August 2019
11 Reads

Resection of tumors within the primary motor cortex using high-frequency stimulation: oncological and functional efficiency of this versatile approach based on clinical conditions.

J Neurosurg 2019 Aug 9:1-13. Epub 2019 Aug 9.

1Neurosurgical Oncology Unit, Department of Oncology and Hemato-Oncology.

Objective: Brain mapping techniques allow one to effectively approach tumors involving the primary motor cortex (M1). Tumor resectability and maintenance of patient integrity depend on the ability to successfully identify motor tracts during resection by choosing the most appropriate neurophysiological paradigm for motor mapping. Mapping with a high-frequency (HF) stimulation technique has emerged as the most efficient tool to identify motor tracts because of its versatility in different clinical settings. Read More

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http://dx.doi.org/10.3171/2019.5.JNS19453DOI Listing
August 2019
2 Reads

Management of epilepsy in brain tumors.

Neurol Sci 2019 Oct 7;40(10):2217-2234. Epub 2019 Aug 7.

Department of Neurosciences, IRCCS Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.

Epilepsy in brain tumors (BTE) may require medical attention for a variety of unique concerns: epileptic seizures, possible serious adverse effects of antineoplastic and antiepileptic drugs (AEDs), physical disability, and/or neurocognitive disturbances correlated to tumor site. Guidelines for the management of tumor-related epilepsies are lacking. Treatment is not standardized, and overall management might differ according to different specialists. Read More

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http://dx.doi.org/10.1007/s10072-019-04025-9DOI Listing
October 2019
13 Reads
1.495 Impact Factor

Tarik Syndrome: Reversible Postoperative Blindness Secondary to Occipital Seizures.

World Neurosurg 2019 Nov 31;131:58-61. Epub 2019 Jul 31.

Department of Neurosurgery, Loyola University Medical Center, Maywood, Illinois, USA.

Background: Postoperative blindness is a devastating surgical complication. Although usually associated with prolonged cardiac and prone spinal operations, it may follow other procedures as well. Postoperative blindness is most commonly caused by a vascular etiology, but it can more rarely be caused by status epilepticus. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.07.186DOI Listing
November 2019
1 Read

Continuous EEG monitoring after brain tumor surgery.

Acta Neurochir (Wien) 2019 09 6;161(9):1835-1843. Epub 2019 Jul 6.

Department of Neuroscience, Neurosurgery, Uppsala University, University Hospital, S-751 85, Uppsala, Sweden.

Background: Prolonged seizures generate cerebral hypoxia and increased intracranial pressure, resulting in an increased risk of neurological deterioration, increased long-term morbidity, and shorter survival. Seizures should be recognized early and treated promptly. The aim of the study was to investigate the occurrence of postoperative seizures in patients undergoing craniotomy for primary brain tumors and to determine if non-convulsive seizures could explain some of the postoperative neurological deterioration that may occur after surgery. Read More

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http://link.springer.com/10.1007/s00701-019-03982-6
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http://dx.doi.org/10.1007/s00701-019-03982-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704081PMC
September 2019
4 Reads

Case of anti-Hu antibody-mediated encephalopathy associated with ovarian cancer.

J Obstet Gynaecol Res 2019 Sep 3;45(9):1948-1951. Epub 2019 Jul 3.

Department of Obstetrics and Gynecology, Yokohama Municipal Citizen's Hospital, Yokohama, Japan.

The present report describes a case of anti-Hu antibody-mediated encephalopathy associated with ovarian cancer. The patient developed paraneoplastic neurologic syndromes (PNS) during the course of ovarian cancer and showed a symptom of jargon aphasia; diagnosis of PNS was made on the basis of serological and cerebrospinal examination, electroencephalogram (EEG), and magnetic resonance images. EEG initially indicated a condition of non-convulsive status epilepticus; however, levetiracetam administration facilitated complete recovery of this condition. Read More

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http://dx.doi.org/10.1111/jog.14031DOI Listing
September 2019
5 Reads

[Patients with anti-GABA (B) receptor encephalitis: 8 cases report].

Zhonghua Yi Xue Za Zhi 2019 Jul;99(25):1985-1988

Department of Neurology, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, China.

To discuss the clinical features, diagnosis, therapy and prognosis of anti-GABA (B) receptor encephalitis. Clinical data of patients with anti-gaba B receptor encephalitis admitted to the department of neurology of the second hospital of hebei medical university from April 2016 to February 2018 were collected and retrospectively analyzed. Eight patients with anti-GABA (B) receptor encephalitis were included. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.25.017DOI Listing
July 2019
4 Reads

Herpes Simplex Encephalitis Initially Erroneously Diagnosed as Glioma of the Cerebellum: Case Report and Literature Review.

World Neurosurg 2019 Sep 26;129:421-427. Epub 2019 Jun 26.

Neurosurgical Department, Pediatric Hospital of Athens, 'Agia Sophia', Athens, Greece.

Background: Herpes simplex encephalitis caused by herpes simplex has an estimated annual prevalence in the order of 1 in 250,000 to 500,000 patients and is considered to be the most usually encountered nonendemic pathogenic cause of lethal encephalitis in well-developed countries. There are a few cases reported in the literature in which a diagnostic dilemma between was raised between herpes simplex encephalitis and brain glioma and a definitive diagnosis was difficult to obtain.

Case Description: We report the case of a 5-year-old girl with a previous medical history of premature thelarche. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.06.158DOI Listing
September 2019
10 Reads

Clinical Features, Treatment, and Outcomes Among Chinese Children With Anti-methyl-D-aspartate Receptor (Anti-NMDAR) Encephalitis.

Front Neurol 2019 6;10:596. Epub 2019 Jun 6.

Department of Neurology, Children's Hospital of Fudan University, Shanghai, China.

Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is the most common form of autoimmune encephalitis in pediatric patients. In this study, we aimed to investigate the clinical features and long-term outcomes of pediatric patients with anti-NMDAR encephalitis in China. We conducted a retrospective study of children (age range: 0-18 years) with anti-NMDAR encephalitis treated at Children's Hospital of Fudan University between July 2015 and November 2018. Read More

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http://dx.doi.org/10.3389/fneur.2019.00596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562280PMC
June 2019
9 Reads

Stereotactic thermocoagulation for insular epilepsy: Lessons from successes and failures.

Epilepsia 2019 08 17;60(8):1565-1579. Epub 2019 Jun 17.

Department of Neurosurgery, Sainte-Anne Hospital, Paris-Descartes University, Paris, France.

Objective: To assess factors associated with favorable outcome in refractory insular epilepsy treated by volume-based stereotactic radiofrequency thermocoagulation (RFTC).

Methods: We performed volume-based RFTC in 19 patients (11 males, 7-44 years old). The volume for thermocoagulation was identified by multimodal data including electroencephalography (EEG)-video, magnetic resonance imaging (MRI), and fluorodeoxyglucose-positron emission tomography (PET) in all patients, and epileptogenic zone (EZ) was assessed by stereo-electroencephalography (SEEG) in 16. Read More

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http://dx.doi.org/10.1111/epi.16092DOI Listing
August 2019
7 Reads

Periodic focal epileptiform discharges.

Clin Neurophysiol 2019 08 31;130(8):1320-1328. Epub 2019 May 31.

Department of Neurosurgery, Mayo Clinic, Jacksonville, FL, USA.

Objective: To report intraoperative periodic focal epileptiform discharges (PFEDs) during awake craniotomy using high-density electrocorticography (HD-ECoG).

Methods: We retrospectively analyzed 81 patients undergoing awake craniotomy between 9/29/2016 and 7/5/2018. Intraoperative HD-ECoG was performed with direct electrocortical stimulation (DECS) for functional brain mapping. Read More

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http://dx.doi.org/10.1016/j.clinph.2019.04.718DOI Listing
August 2019
6 Reads

Molecular Mechanisms of Cancer-Induced Sleep Disruption.

Int J Mol Sci 2019 Jun 6;20(11). Epub 2019 Jun 6.

Department of Psychiatry & Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA.

Sleep is essential for health. Indeed, poor sleep is consistently linked to the development of systemic disease, including depression, metabolic syndrome, and cognitive impairments. Further evidence has accumulated suggesting the role of sleep in cancer initiation and progression (primarily breast cancer). Read More

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http://dx.doi.org/10.3390/ijms20112780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600154PMC
June 2019
22 Reads

Neurophysiological evidence of impaired attention and working memory in untreated hematologic cancer patients.

Clin Neurophysiol 2019 08 24;130(8):1243-1252. Epub 2019 May 24.

Department of Neurological Sciences, College of Medicine, University of Nebraska Medical Center (UNMC), United States; Fred & Pamela Buffett Cancer Center, UNMC, United States.

Objective: Neuroimaging studies of hematologic cancer patients report altered activity in dorsal attention and central executive networks. To determine the consequences of these altered brain networks, we evaluated neurophysiological correlates of attention and working memory in hematologic cancer patients prior to initiating treatment.

Methods: Hematologic cancer patients (19-80 years) were excluded for premorbid cognitive impairment, prior non-hematologic cancer diagnosis, and prior chemotherapy. Read More

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http://dx.doi.org/10.1016/j.clinph.2019.04.714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613795PMC
August 2019
6 Reads

Electroencephalographic correlates of hypnosedation during breast cancer surgery.

Breast J 2019 07 24;25(4):786-787. Epub 2019 May 24.

Department of Palliative, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1111/tbj.13328DOI Listing
July 2019
2 Reads

Herpes Simplex Virus 1 encephalitis with normal cerebrospinal fluid after brain radiotherapy in a patient with glioblastoma. A case report and review of literature.

Acta Biomed 2019 05 23;90(2):327-330. Epub 2019 May 23.

Neurology Department, Parma Hospital.

Herpes simplex virus encephalitis (HSE) is the most common cause of letal encephalitis and its prevalence appears higher among oncologic patients who undergo brain radiotherapy (RT). We describe a case of 76-year-old woman with glioblastoma multiforme (GBM) who developed HSE shortly after brain RT. Cerebrospinal fluid analysis (CSF) was normal and the diagnosis was driven by brain MRI and EEG. Read More

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http://dx.doi.org/10.23750/abm.v90i2.8218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776207PMC
May 2019
8 Reads

Potential Intra- or Cross-Network Functional Reorganization of the Triple Unifying Networks in Patients with Frontal Glioma.

World Neurosurg 2019 Aug 8;128:e732-e743. Epub 2019 May 8.

Department of Neurosurgery, the Affiliated Brain Hospital of Nanjing Medical University, Nanjing, Jiangsu, China; Institute of Brain Functional Imaging, Nanjing Medical University, Nanjing, Jiangsu, China. Electronic address:

Background: Patients with frontal glioma might experience cognition alterations together with potential dysfunction of resting-state networks (RSNs). To understand the altered patterns of the intrinsic activity and underlying network interactions between the cognitive-related RSNs is of great importance.

Objective: This study aimed to investigate the characteristics of the altered RSNs, including default mode network, executive control network, and salience network and further elucidate the possible functional reorganization of RSNs in patients with frontal glioma. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.04.248DOI Listing
August 2019
2 Reads
2.417 Impact Factor

Multinodular and vacuolating neuronal tumour of the cerebrum: a rare neuroimaging incidentaloma or a potentially treatable cause of focal epilepsy?

Epileptic Disord 2019 Apr;21(2):209-214

Clinic of Neurology.

Multinodular and vacuolating neuronal tumour (MVNT) of the cerebrum is a relatively new, well defined histopathological and neuroradiological entity, in many cases associated with an early adult-onset epilepsy. These lesions have an indolent course and resemble both malformative and neoplastic processes, combining a focal developmental anomaly and a low-grade tumour. Herein, we report a case of a 48-year-old female patient with left temporal lobe epilepsy associated with MVNT. Read More

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http://dx.doi.org/10.1684/epd.2019.1045DOI Listing
April 2019
8 Reads

Contribution of geriatric model to the management of an epileptic seizure or epilepsy.

Geriatr Psychol Neuropsychiatr Vieil 2019 Mar;17(S1):21-24

Centre de gériatrie, Pavillon Bottard et CMRR Paris-Sud, Hôpital Pitié-Salpêtrière, AP-HP, Paris, France, DHU FAST, Sorbonne-Université, Paris, France.

Epileptic seizures and epilepsy appear frequent in the elderly. The diagnosis is often more difficult and therapeutic decisions are often debated. In this context, the implementation of a rigorous analysis and reasoning to correctly determine the various components at the origin of the epileptic seizure is fundamental. Read More

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http://dx.doi.org/10.1684/pnv.2019.0791DOI Listing
March 2019
2 Reads

Neurological toxicities associated with chimeric antigen receptor T-cell therapy.

Brain 2019 05;142(5):1334-1348

Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Chimeric antigen receptor T cell therapy has become an important tool in the treatment of relapsed and refractory malignancy; however, it is associated with significant neurological toxicity. We characterized the neurological toxicity associated with chimeric antigen receptor T-cell therapy in a consecutive series of 100 patients up to 2 months post transfusion, 28 of whom were obtained from chart review and the others by prospective observation. The underlying neoplasms were lymphoma (74%), myeloma (14%), leukaemia (10%), and sarcoma (2%). Read More

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http://dx.doi.org/10.1093/brain/awz053DOI Listing
May 2019
37 Reads
9.196 Impact Factor

Variations in electroencephalography with mobile phone usage in medical students.

Neurol India 2019 Jan-Feb;67(1):235-241

Department of Neurology, King George's Medical University, Lucknow, Uttar Pradesh, India.

Background: Electromagnetic fields (EMFs) emitted by cellular telephones may cause neurological ill effects like cognitive dysfunction, emotional instability, and even brain tumors. Slowing of brain activity on electroencephalography (EEG) has been shown. However, these findings need further validation. Read More

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http://dx.doi.org/10.4103/0028-3886.253610DOI Listing
January 2020
26 Reads

Diagnostic and therapeutic values of intraoperative electrophysiological neuromonitoring during resection of intradural extramedullary spinal tumors: a single-center retrospective cohort and meta-analysis.

J Neurosurg Spine 2019 Mar 1:1-11. Epub 2019 Mar 1.

1Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.

OBJECTIVEWith the advent of intraoperative electrophysiological neuromonitoring (IONM), surgical outcomes of various neurosurgical pathologies, such as brain tumors and spinal deformities, have improved. However, its diagnostic and therapeutic value in resecting intradural extramedullary (ID-EM) spinal tumors has not been well documented in the literature. The objective of this study was to summarize the clinical results of IONM in patients with ID-EM spinal tumors. Read More

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http://dx.doi.org/10.3171/2018.11.SPINE181095DOI Listing
March 2019
11 Reads

A Systematic Review of the Effect of Neurofeedback in Cancer Patients.

Integr Cancer Ther 2019 Jan-Dec;18:1534735419832361

1 Clinic for Psychosomatic Medicine and Psychotherapy, LVR Hospital Essen, University of Duisburg-Essen, Essen, Germany.

Introduction: Neurofeedback (NF) or electroencephalogram (EEG)-Biofeedback is a drug-free form of brain training to directly alter the underlying neural mechanisms of cognition and behavior. It is a technique that measures a subject's EEG signal, processes it in real time, with the goal to enable a behavioral modification by modulating brain activity. The most common application of the NF technology is in epilepsies, migraine, attention-deficit/hyperactivity disorder, autism spectrum disorder, affective disorders, and psychotic disorders. Read More

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http://dx.doi.org/10.1177/1534735419832361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416750PMC
December 2019
20 Reads

[Clinical analysis of 71 cases of anti-N-methyl-D-aspartate receptor encephalitis in children].

Zhonghua Er Ke Za Zhi 2019 Feb;57(2):125-130

Department of Pediatrics, Xiangya Hospital of Central South University, Hunan Intellectual and Developmental Disabilities Research Center, Changsha 410008, China.

To investigate the clinical features, treatment strategies and long term outcomes of children with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis. The data of clinical features, auxiliary examinations, treatments and prognosis in children with anti-NMDAR encephalitis in Xiangya Hospital of Central South University from March 2014 to October 2017 were collected and retrospectively analyzed. A total of 71 patients were enrolled, including 33 males and 38 females. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0578-1310.2019.02.012DOI Listing
February 2019
3 Reads

Clinical and EEG Characteristics of Ifosfamide-Related Encephalopathy.

J Clin Neurophysiol 2019 Mar;36(2):150-154

Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, New York, U.S.A.

Purpose: Ifosfamide can lead to a syndrome of central nervous system toxicity. Here, we investigate the clinical and EEG characteristics of patients with ifosfamide-related encephalopathy.

Methods: Retrospective data were collected on patients from Memorial Sloan Kettering Cancer Center, who developed encephalopathy associated with ifosfamide between 2007 and 2017. Read More

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http://Insights.ovid.com/crossref?an=00004691-900000000-9948
Publisher Site
http://dx.doi.org/10.1097/WNP.0000000000000539DOI Listing
March 2019
53 Reads

A miniature multi-contrast microscope for functional imaging in freely behaving animals.

Nat Commun 2019 01 9;10(1):99. Epub 2019 Jan 9.

Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.

Neurovascular coupling, cerebrovascular remodeling and hemodynamic changes are critical to brain function, and dysregulated in neuropathologies such as brain tumors. Interrogating these phenomena in freely behaving animals requires a portable microscope with multiple optical contrast mechanisms. Therefore, we developed a miniaturized microscope with: a fluorescence (FL) channel for imaging neural activity (e. Read More

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http://dx.doi.org/10.1038/s41467-018-07926-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327063PMC
January 2019
10 Reads

The Resistivity of Human Brain Tumours In Vivo.

Authors:
J Latikka H Eskola

Ann Biomed Eng 2019 Mar 4;47(3):706-713. Epub 2019 Jan 4.

Faculty of Biomedical Sciences and Engineering, Tampere University of Technology, Tampere, Finland.

The histological structure of tumour tissues differs from healthy brain tissues. It can therefore be assumed that there are differences also in the electrical characteristics of these tissues. The electrical characteristics of the tissues define how electric current is distributed within volume conductors, such as the human body or head. Read More

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http://dx.doi.org/10.1007/s10439-018-02189-7DOI Listing
March 2019
9 Reads

Interictal Slow and High-Frequency Oscillations: Is it an Epileptic Slow or Red Slow?

J Clin Neurophysiol 2019 Mar;36(2):166-170

Department of Epilepsy, Movement Disorders and Physiology, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto, Japan.

Purpose: We reported the presence of interictal slow and high-frequency oscillations (HFOs) (IIS + HFO) and its temporal change so as to elucidate its clinical usefulness as a surrogate marker of epileptogenic zone in a patient with intractable focal epilepsy.

Methods: We focused on one of the core electrodes of epileptogenicity, and investigated IIS + HFO in the pre- and post-segment of 30 minutes to all the 6 seizures. We adopted interictal slow in duration of 0. Read More

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http://dx.doi.org/10.1097/WNP.0000000000000527DOI Listing
March 2019
8 Reads

The Influence of Anesthesia on Corticocortical Evoked Potential Monitoring Network Between Frontal and Temporoparietal Cortices.

World Neurosurg 2019 Mar 18;123:e685-e692. Epub 2018 Dec 18.

Department of Neurosurgery, Sapporo Medical University, Sapporo, Hokkaido, Japan. Electronic address:

Background: Previous studies have reported the usefulness of intraoperative corticocortical evoked potentials (CCEPs) for preserving language function during brain surgery.

Objective: This study aimed to assess the influence of depth of anesthesia on CCEP to establish its clinical utility.

Methods: Twenty patients with brain tumors or epilepsy who underwent awake craniotomy were included in this study. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183282
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http://dx.doi.org/10.1016/j.wneu.2018.11.253DOI Listing
March 2019
30 Reads

Surgical strategy for temporal lobe epilepsy with dual pathology and incomplete evidence from EEG and neuroimaging.

Exp Ther Med 2018 Dec 19;16(6):4886-4892. Epub 2018 Sep 19.

Department of Neurosurgery, The Second Hospital of Dalian Medical University, Dalian, Liaoning 116000, P.R. China.

Coexistence of hippocampal sclerosis (HS) and a temporal neocortical lesion, including focal cortical dysplasia, vascular malformations or benign primary brain tumors, is defined as dual pathology. In the majority of cases, the complete evidence based on electroencephalogram (EEG) and magnetic resonance imaging (MRI) for each of the dual pathological lesions is difficult to obtain. As a result, patients with dual pathology are poor surgical candidates due to potential incomplete resection of the epileptogenic zone. Read More

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http://dx.doi.org/10.3892/etm.2018.6774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256846PMC
December 2018
3 Reads

Age-dependent semiology of frontal lobe seizures.

Epilepsy Res 2019 01 23;149:83-87. Epub 2018 Oct 23.

Epilepsy Center, University Medical Center, University of Freiburg, Germany; Faculty of Medicine, University of Freiburg, Germany. Electronic address:

Introduction: Frontal lobe epilepsy is the second most frequent origin of focal epilepsy. Various studies have discussed localizing aspects of ictal signs in frontal lobe epilepsy; the effect of age on semiological manifestations has, however, not been analyzed so far.

Material And Methods: We retrospectively analyzed video-documented semiological signs in a cohort of 122 consecutive patients aged 0-70 years (mean age: 24. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09201211183040
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http://dx.doi.org/10.1016/j.eplepsyres.2018.10.007DOI Listing
January 2019
55 Reads

Histopathologic and Clinical Correlation of Aberrant Neuromagnetic Activities with Low to High Frequency of Gliomas.

World Neurosurg 2019 Mar 8;123:e609-e620. Epub 2018 Dec 8.

Department of Neurosurgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China. Electronic address:

Objective: To quantify the low- to high-frequency range of abnormal brain activities and assess the histopathologic and clinical correlation in patients with glioma.

Methods: Twenty-five patients with glioma and 20 healthy controls were examined with a magnetoencephalography (MEG) system. MEG data collected in 6 frequency bands, including 1-4 Hz, 4-8 Hz, 8-12 Hz, 12-30 Hz, 30-45 Hz, and 55-75 Hz, were analyzed by neuropathology to assess neuromagnetic signatures of glioma grade. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.11.235DOI Listing
March 2019
19 Reads

Clinical utility of portable electrophysiology to measure fatigue in treatment-naïve non-small cell lung cancer.

Support Care Cancer 2019 Jul 22;27(7):2617-2623. Epub 2018 Nov 22.

Academic Department of Palliative Medicine, Our Lady's Hospice & Care Services, Harold's Cross, Dublin, Ireland.

Purpose: Cancer-related fatigue (CRF) biology remains poorly understood. Responsible mechanisms may be central or peripheral and originate anywhere from the brain to muscle fiber. Objective measurement is complex and previously limited to specialized laboratories. Read More

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http://dx.doi.org/10.1007/s00520-018-4542-1DOI Listing
July 2019
6 Reads

Immunotherapy for anti-NMDA receptor encephalitis: Experience from a single center in Taiwan.

Pediatr Neonatol 2019 08 31;60(4):417-422. Epub 2018 Oct 31.

Chang Gung Children's Hospital Study Group for Children with Encephalitis/Encephalopathy Related Status Epilepticus and Epilepsy (CHEESE), Taoyuan, Taiwan.

Background: Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an anti-neuronal antibody-mediated inflammatory brain disease that causes severe psychiatric and neurological deficits in previously healthy patients. The aims of this study were to demonstrate the clinical characteristics of patients diagnosed with anti-NMDA receptor encephalitis and to compare the different treatment strategies among these patients.

Methods: Patients presenting with newly acquired psychiatric and/or neurological deficits were studied retrospectively from 2009 to 2017. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18759572183035
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http://dx.doi.org/10.1016/j.pedneo.2018.10.006DOI Listing
August 2019
54 Reads

Exploratory Study of Low Resolution Electromagnetic Tomography (LORETA) Real-Time Z-Score Feedback in the Treatment of Pain in Patients with Head and Neck Cancer.

Brain Topogr 2019 03 13;32(2):283-285. Epub 2018 Nov 13.

Department of Palliative, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1414, FCT5.6006, Houston, TX, 77030, USA.

Acute pain from mucositis in patients with head and neck cancer (HNC) undergoing radiation therapy (RT) is common, and may not respond well to narcotics. We used low resolution electromagnetic tomography z-score neurofeedback (LFBz) to investigate whether patients could modify brain wave activity associated with acute pain and whether this would reduce the experience of pain. HNC patients scheduled for RT had baseline pre-pain onset measures (EEG and numeric rating scale) collected before RT and then at pain onset before using analgesics, after each LFBz session and at the end of RT. Read More

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http://link.springer.com/10.1007/s10548-018-0686-z
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http://dx.doi.org/10.1007/s10548-018-0686-zDOI Listing
March 2019
39 Reads

Cancer frequency detected by positron emission tomography-computed tomography in limbic encephalitis.

Epilepsy Behav 2018 Dec 6;89:105-111. Epub 2018 Nov 6.

Department of Epileptology, University of Bonn, Sigmund-Freud-Straße 25, 53127 Bonn, Germany.

Objective: Paraneoplastic limbic encephalitis (LE) occurs frequently with considerable variability according to literature reports. We thus determined the cancer frequency in mixed LE subtypes sharing the diagnosis of temporal lobe epilepsy (TLE).

Methods: All patients underwent magnetic resonance imaging (MRI) of the brain, electroencephalography (EEG) recordings, neuropsychological testing, immunohistochemistry, and clinical examination together with whole body 2-fluor-2-desoxy-d-glucose (FDG)-positron emission tomography (PET)/computed tomography (CT) to detect cancer in this observatory study. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15255050183072
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http://dx.doi.org/10.1016/j.yebeh.2018.09.043DOI Listing
December 2018
22 Reads

Migraine-like visual aura: Can it be an early-onset symptom of astrocytoma?

Agri 2018 Oct;30(4):202-205

Department of Neurology, Kocaeli Derince Training and Research Hospital, Kocaeli, Turkey.

Photopsia, fortification spectra, and the slow propagation of a scintillating scotoma across the visual field are typical diagnostic features of the visual aura of migraine. In the vast majority of cases, the diagnosis can be made without the need for further investigations. Herein, we report three consecutive cases with an astrocytoma and discuss clinical features of migraine-like visual aura. Read More

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http://dx.doi.org/10.5505/agri.2017.77598DOI Listing
October 2018
5 Reads

Ictal SPECT reveals different epileptogenic zones in frontal lobe epilepsy.

Epileptic Disord 2018 Oct;20(5):447-450

Epilepsy Center, Department of Neurology, University of Munich, Munich, Germany.

We report a patient with frontal lobe epilepsy due to a right frontal astrocytoma (WHO Grade III) in whom two ictal SPECTs (single photon emission tomography) were performed during two seizures with different semiology and different EEG seizure patterns. Subtraction of ictal and interictal SPECT showed right lateral frontal hyperperfusion during a left face clonic seizure, and right mesial fronto-polar hyperperfusion during a subclinical seizure. This report demonstrates that ictal SPECT may reflect different seizure semiology from the frontal lobe of the same individual and that simultaneous EEG is indispensable for the correct interpretation of SPECT in epilepsy. Read More

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http://dx.doi.org/10.1684/epd.2018.0991DOI Listing
October 2018
39 Reads