217 results match your criteria EEG Triphasic Waves


A Mean Field Model of Acute Hepatic Encephalopathy.

Conf Proc IEEE Eng Med Biol Soc 2018 Jul;2018:2366-2369

Acute hepatic encephalopathy (AHE) is a common form of delirium, a state of confusion, impaired attention, and decreased arousal due to acute liver failure. However, the neurophysiological mechanisms underlying AHE are poorly understood. In order to develop hypotheses for mechanisms of AHE, our work builds on an existing neural mean field model for similar EEG patterns in cerebral anoxia, the bursting Liley model. Read More

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http://dx.doi.org/10.1109/EMBC.2018.8512786DOI Listing
July 2018
1 Read

Triphasic Waves and Encephalopathy in the Setting of Pregabalin Toxicity.

J Clin Neurophysiol 2018 Nov;35(6):515-517

Department of Neurology, Johns Hopkins Bayview Medical Center, Baltimore, Maryland, U.S.A.

EEG triphasic waves are usually seen in the setting of metabolic encephalopathies, but may also occur secondary to medication toxicity. There are few reports of medications causing continuous triphasic waves, and only rare reports in the literature show an association between these discharges and pregabalin toxicity. Here, we describe triphasic waves in a patient with underlying white matter lesions, as well as pregabalin toxicity, secondary to renal insufficiency. Read More

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http://dx.doi.org/10.1097/WNP.0000000000000511DOI Listing
November 2018
6 Reads

[Clinical, neuroimaging and genetic features of two Chinese families with fatal familial insomnia].

Zhonghua Yi Xue Za Zhi 2018 Aug;98(31):2501-2504

Department of Neurology, the Navy General Hospital, Beijing 100048, China.

To examine clinical, neuroimaging and genetic features of two Chinese families with fatal familial insomnia (FFI). The clinical data, including case history, physical examination, biochemical analysis of blood and neuroimaging of two pedigrees with FFI who admitted to the Navy General Hospital in 2014 and 2017 were collected. The D178N prion protein (PRNP) mutation were determined by DNA sequencing among the proband and family members. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2018.31.010DOI Listing
August 2018
1 Read

Baclofen-induced encephalopathy in overdose - Modeling of the electroencephalographic effect/concentration relationships and contribution of tolerance in the rat.

Prog Neuropsychopharmacol Biol Psychiatry 2018 Aug 18;86:131-139. Epub 2018 May 18.

Inserm UMRS-1144, Paris-Descartes University, Paris, France.

Baclofen, a γ-amino-butyric acid type-B receptor agonist with exponentially increased use at high-dose to facilitate abstinence in chronic alcoholics, is responsible for increasing poisonings. Baclofen overdose may induce severe encephalopathy and electroencephalographic (EEG) abnormalities. Whether prior prolonged baclofen treatment may influence the severity of baclofen-induced encephalopathy in overdose has not been established. Read More

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http://dx.doi.org/10.1016/j.pnpbp.2018.05.016DOI Listing
August 2018
8 Reads

Low mood, visual hallucinations, and falls - heralding the onset of rapidly progressive probable sporadic Creutzfeldt-Jakob disease in a 73-year old: a case report.

J Med Case Rep 2018 May 8;12(1):128. Epub 2018 May 8.

Chelsea and Westminster Hospitals NHS Foundation Trust, West Middlesex University Hospital, Twickenham Rd, Isleworth, TW7 6AF, UK.

Background: Creutzfeldt-Jakob disease is a rare and rapidly fatal neurodegenerative disease. Since clinicians may see only very few cases during their professional career, it is important to be familiar with the clinical presentation and progression, to perform appropriate investigations, and allow for quick diagnosis.

Case Presentation: A 73-year-old British Caucasian woman presented with acute confusion of 2 weeks' duration on a background of low mood following a recent bereavement. Read More

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http://dx.doi.org/10.1186/s13256-018-1649-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938807PMC
May 2018
3 Reads

The Relationship of Triphasic Waves with Intracranial Pressure as a Possible Prognostic Marker in Traumatic Brain Injury.

Case Rep Neurol Med 2017 28;2017:4742026. Epub 2017 Nov 28.

Department of Neurology, University of Missouri, 5 Hospital Drive, CE 540, Columbia, MO 65211, USA.

Background: Continuous electroencephalography (CEEG) monitoring is used for detection of convulsive and nonconvulsive seizures and assessing the degree of encephalopathy in critically ill patients. A commonly seen encephalopathic pattern on CEEG is generalized periodic discharges with triphasic wave (TW) morphology. The underlying role and prognostic significance of TW in relationship to intracranial pressure (ICP) remain unknown. Read More

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http://dx.doi.org/10.1155/2017/4742026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727623PMC
November 2017
4 Reads

Cefepime induced neurotoxicity: A case series and review of the literature.

eNeurologicalSci 2017 Sep 4;8:40-43. Epub 2017 Aug 4.

Department of Neurology, Boston University School of Medicine, Boston, MA, United States.

Cefepime is a fourth generation cephalosporin which is bactericidal for broad spectrum of organisms. This is a case-series of three patients who presented to our hospital with confusion secondary to cefepime use to treat urinary tract infection (UTI) and health care associated pneumonia (HCAP), after excluding other common etiologies of altered mental status (AMS). Of these three patients, one had progressive expressive aphasia and the other two demonstrated asynchronous myoclonic activity of the limbs. Read More

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http://dx.doi.org/10.1016/j.ensci.2017.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730896PMC
September 2017
6 Reads

Generalized Periodic Discharges With and Without Triphasic Morphology.

J Clin Neurophysiol 2018 Mar;35(2):144-150

Neurological Institute, University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland, Ohio, U.S.A.

Purpose: Generalized periodic discharges (GPDs) with a triphasic morphology have been associated with nonepileptic encephalopathies. We conducted the study to assess the reliability in which electroencephalographers can differentiate triphasic from nontriphasic periodic discharges and to evaluate for the presence of electroencephalogram and clinical characteristics that are associated with a higher risk of seizures.

Methods: We studied prospectively 92 patients between May 2016 and February 2017. Read More

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http://dx.doi.org/10.1097/WNP.0000000000000441DOI Listing
March 2018
4 Reads
1.600 Impact Factor

[Portal-systemic encephalopathy with bilateral thalamic and internal capsule lesions using diffusion-weighted MRI in a super-aged patient].

Rinsho Shinkeigaku 2017 Dec 28;57(12):759-763. Epub 2017 Nov 28.

Department of Neurology, Nanpuh Hospital.

We describe the case of a 90-year-old woman who was hospitalized in July 2016 and subsequently experienced a sudden decline in consciousness level resulting in a state of deep coma. Involuntary movements were not observed, and bilateral Babinski signs were inconclusive. Diffusion-weighted MRI (DWI) of the brain showed bilateral hyperintensity in the thalamus and internal capsule, laboratory testing detected high levels of plasma ammonia, and an electroencephalogram showed delta waves and triphasic waves predominantly in the frontal lobe. Read More

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http://dx.doi.org/10.5692/clinicalneurol.cn-001068DOI Listing
December 2017
6 Reads

Cefepime-induced neurotoxicity: a systematic review.

Crit Care 2017 Nov 14;21(1):276. Epub 2017 Nov 14.

Department of Pharmacy and Critical Care, Maine Medical Center, 22 Bramhall St, Portland, ME, 04102, USA.

Background: Cefepime is a widely used antibiotic with neurotoxicity attributed to its ability to cross the blood-brain barrier and exhibit concentration-dependent ϒ-aminobutyric acid (GABA) antagonism. Neurotoxic symptoms include depressed consciousness, encephalopathy, aphasia, myoclonus, seizures, and coma. Data suggest that up to 15% of ICU patients treated with cefepime may experience these adverse effects. Read More

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http://dx.doi.org/10.1186/s13054-017-1856-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686900PMC
November 2017
6 Reads

Pregabalin Toxicity Manifesting as Reversible Encephalopathy With Continuous Triphasic Waves in Electroencephalogram.

Clin Neuropharmacol 2017 Sep/Oct;40(5):226-228

*Department of Neurology, and †Department of Nephrology, Narayana Health City, Bangalore, India.

A 74-year-old man with peripheral neuropathy due to diabetes presented with deliberate ingestion of 450 mg of pregabalin (PBG) over a period of 8 hours followed by altered mental status. A bedside electroencephalogram was performed to rule out nonconvulsive status epilepticus, which showed continuous triphasic waves (TWs) with slow background activity. He recovered after 48 hours of stopping PBG, and his repeat electroencephalogram after 72 hours did not show any TWs. Read More

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http://dx.doi.org/10.1097/WNF.0000000000000245DOI Listing

Outcomes of patients with altered level of consciousness and abnormal electroencephalogram: A retrospective cohort study.

PLoS One 2017 8;12(9):e0184050. Epub 2017 Sep 8.

Department of Clinical Neurophysiology, Hospital Israelita Albert Einstein, São Paulo, Brazil.

Introduction: Nonconvulsive seizures (NCS) are frequent in hospitalized patients and may further aggravate injury in the already damaged brain, potentially worsening outcomes in encephalopathic patients. Therefore, both early seizure recognition and treatment have been advocated to prevent further neurological damage.

Objective: Evaluate the main EEG patterns seen in patients with impaired consciousness and address the effect of treatment with antiepileptic drugs (AEDs), continuous intravenous anesthetic drugs (IVADs), or the combination of both, on outcomes. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0184050PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590878PMC
November 2017
9 Reads

Electroencephalographic findings in patients with circumscribed thalamic lesions.

Epilepsy Res 2017 09 15;135:115-122. Epub 2017 Jun 15.

Department of Neurology, University Hospital Ulm, Oberer Eselsberg 45, 89081 Ulm, Germany; Epilepsy Center Bethel, Mara Hospital, Maraweg 21, 33617 Bielefeld, Germany. Electronic address:

Introduction: Thalamo-cortical networks have mainly been studied in the generation of idiopathic (genetic) epilepsies. The purpose of this study was to analyze EEG patterns and the occurrence of focal (symptomatic) epileptic seizures in patients with acquired circumscribed thalamic lesions.

Patients And Methods: Among 596 patients with thalamic lesions, we identified 47 patients in whom circumscribed thalamic lesions were detected by MRI and who underwent an EEG examination at the same stay at hospital. Read More

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http://dx.doi.org/10.1016/j.eplepsyres.2017.06.009DOI Listing
September 2017
8 Reads

Diagnostic Yield of Routine Electroencephalography With Concurrent Video Recording in Detecting Interictal Epileptiform Discharges in Relation to Reasons for Request: A Prospective Study of 1,080 Video-Electroencephalograms.

J Clin Neurophysiol 2017 Sep;34(5):434-437

Department of Neurosciences, Hospital Universitari Germans Trias i Pujol, Badalona, Spain.

Purpose: The aim of this study was to prospectively analyze the sensitivity and specificity of routine electroencephalography with concurrent video recording (vEEG) in relation to the reasons for requesting the test and to investigate when routine vEEG should be requested.

Methods: We prospectively analyzed 1,080 consecutive vEEGs performed between April 2015 and April 2016. The requests for vEEG were classified as requests with a low suspicion of epilepsy (syncope, confusion or delirium, suspicion of psychogenic nonepileptic seizures, and paroxysmal focal neurological deficit) or requests with a high suspicion of epilepsy (first clinical seizure, suspected status epilepticus, follow-up study of a patient with epilepsy, and acute symptomatic seizures). Read More

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http://dx.doi.org/10.1097/WNP.0000000000000390DOI Listing
September 2017
20 Reads

The relationship between epileptiform discharges and background activity in the visual analysis of electroencephalographic examinations in dogs with seizures of different etiologies.

Vet J 2017 Apr 16;222:41-51. Epub 2017 Mar 16.

Department of Neurology, Wrocław Medical University, ul. Borowska 213, 50-556 Wrocław, Poland.

Electroencephalographic (EEG) recordings in 125 outpatient dogs with various epileptiform encephalopathies were acquired under medetomidine sedation using subdermal wire electrodes. The features of canine EEG (background activity [BGA] and epileptiform discharges [EDs]) were assessed, described and compared. The dogs included neurologically healthy controls (N, n = 19), dogs with portosystemic shunt (PSS, n = 9), dogs with intracranial pathologies (IP, n = 27) and dogs with idiopathic epilepsy (IE, n = 70). Read More

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http://dx.doi.org/10.1016/j.tvjl.2017.03.003DOI Listing
April 2017
12 Reads

Minimal EEG montage with high yield for the detection of status epilepticus in the setting of postanoxic brain damage.

Acta Neurol Belg 2017 Mar 1;117(1):145-152. Epub 2016 Jul 1.

Department of Neurology, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.

For the diagnosis of electrographic seizures or status epilepticus, we reduced the number of EEG-electrodes to make urgent EEG monitoring more feasible. Unlike the current existing research, with mixed results, we studied a specific population with postanoxic brain damage, expecting a higher yield of detection of ictal EEG patterns. In a population treated with therapeutic hypothermia post-cardiac arrest, the initial EEGs were reformatted in a longitudinal, a hairline and an 8-lead montage, and independently reviewed by two investigators. Read More

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http://dx.doi.org/10.1007/s13760-016-0663-9DOI Listing
March 2017
10 Reads

Associated Factors and Prognostic Implications of Stimulus-Induced Rhythmic, Periodic, or Ictal Discharges.

JAMA Neurol 2016 May;73(5):585-90

Department of Neurology, Mayo Clinic, Rochester, Minnesota.

Importance: The implications of stimulus-induced rhythmic, periodic, or ictal discharges (SIRPIDs) sometimes found on prolonged electroencephalographic (EEG) recordings are uncertain.

Objective: To evaluate the incidence of SIRPIDs and their clinical implications in critically ill patients.

Design, Setting, And Participants: A multicenter, international retrospective study was performed from October 1, 2012, through September 30, 2014, of consecutive adult patients hospitalized in intensive care units with alteration of consciousness who underwent EEG recordings at 3 separate centers. Read More

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http://dx.doi.org/10.1001/jamaneurol.2016.0006DOI Listing
May 2016
12 Reads

Syndrome of transient headache and neurological deficits with cerebrospinal fluid lymphocytosis (HaNDL): A case report with serial electroencephalography (EEG) recordings.. Is there an association with human herpes virus type 7 (HHV-7) infection?

Cephalalgia 2016 Nov 20;36(13):1296-1301. Epub 2016 Jul 20.

1 Department of Neurology and Clinical Neurophysiology, Canisius Wilhelmina Hospital, The Netherlands.

Introduction The syndrome of transient headache and neurological deficits with cerebrospinal fluid lymphocytosis (HaNDL) is a diagnosis made by exclusion. In the literature, different etiological explanations are proposed for HaNDL, including an immune-mediated reaction after a viral infection. Case description We present a case of a 23-year-old woman with several episodes of transient headache, neurological deficits and cerebrospinal fluid lymphocytosis. Read More

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http://dx.doi.org/10.1177/0333102415618616DOI Listing
November 2016
35 Reads

Affair With Triphasic Waves-Their Striking Presence, Mysterious Significance, and Cryptic Origins: What are They?

J Clin Neurophysiol 2015 Oct;32(5):401-5

*Department of Neurology, Johns Hopkins Bayview Medical Center, Baltimore, Maryland, U.S.A.; †Clinic for Intensive Care Medicine, University Hospital Base, Basel, Switzerland; and ‡Department of Neurology, Division of Clinical Neurophysiology, University Hospital Basel, Basel, Switzerland.

Triphasic waves, which have been recorded in the EEG of encephalopathy for more than 50 years, remain clearly identifiable but historically purportedly of uncertain significance. Initially described with liver failure and high serum ammonias, they came to be reported in an ever-expanding list of metabolic, toxic, and structural conditions. Often a dynamic finding (in which the occurrence of triphasic waves might increase or decrease with stimulation or arousal of the patient during EEG), there has been increasing insight into their correlation with multiple concurrent conditions, including subcortical white-matter disease, infections and metabolic disturbances, and their prognostic significance. Read More

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/WNP.0000000000000151DOI Listing
October 2015
48 Reads
6 Citations
1.600 Impact Factor

Stimulus-induced reflex epileptic spasms in 5p- syndrome.

Brain Dev 2016 Feb 18;38(2):261-5. Epub 2015 Aug 18.

Division of Child Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, Yonago, Tottori, Japan.

Here we describe two patients with 5p- syndrome who suffered from epilepsy characterised by stimulus-induced epileptic spasms manifesting as head nodding. In patient 1, a series of spasms were exclusively triggered by eating, and were associated with diffuse high-voltage slow waves on ictal EEG, particularly presenting as a positive slow potential at the left mid-temporal area. Clusters of sharp waves with negative polarity emerged in the same area during the inter-spasm periods during eating. Read More

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http://dx.doi.org/10.1016/j.braindev.2015.08.002DOI Listing
February 2016
13 Reads

Generalized periodic discharges and 'triphasic waves': A blinded evaluation of inter-rater agreement and clinical significance.

Clin Neurophysiol 2016 Feb 7;127(2):1073-1080. Epub 2015 Aug 7.

Emory University School of Medicine, Department of Neurology, 1365 Clifton Rd, Atlanta, GA 30322, USA.

Objectives: Generalized periodic discharges (GPDs) are associated with nonconvulsive seizures. Triphasic waves (TWs), a subtype of GPDs, have been described in relation to metabolic encephalopathy and not felt to be associated with seizures. We sought to establish the consistency of use of this descriptive term and its association with seizures. Read More

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http://dx.doi.org/10.1016/j.clinph.2015.07.018DOI Listing
February 2016
19 Reads

Ictal and interictal EEG patterns in patients with nonconvulsive and subtle convulsive status epilepticus.

Epilepsy Behav 2015 Aug 14;49:263-7. Epub 2015 Jun 14.

National Neuroscience Institute and Singapore General Hospital, Singapore; Dukes-NUS Medical School, Singapore. Electronic address:

Background: Electroencephalography findings in nonconvulsive or subtle convulsive status epilepticus (NCSE and SCSE, respectively) can be heterogenous. We aimed to study the different patterns on EEG in our cohort of patients.

Objective: Our objective was to study ictal and interictal EEG patterns in patients with NCSE and SCSE. Read More

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http://dx.doi.org/10.1016/j.yebeh.2015.05.011DOI Listing
August 2015
7 Reads

Response Rates to Anticonvulsant Trials in Patients with Triphasic-Wave EEG Patterns of Uncertain Significance.

Neurocrit Care 2016 Apr;24(2):233-9

Department of Neurology, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, WACC 735, Boston, MA, 02114, USA.

Background: Generalized triphasic waves (TPWs) occur in both metabolic encephalopathies and non-convulsive status epilepticus (NCSE). Empiric trials of benzodiazepines (BZDs) or non-sedating AED (NSAEDs) are commonly used to differentiate the two, but the utility of such trials is debated. The goal of this study was to assess response rates of such trials and investigate whether metabolic profile differences affect the likelihood of a response. Read More

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http://dx.doi.org/10.1007/s12028-015-0151-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870012PMC
April 2016
4 Reads

Atypical sporadic CJD-MM phenotype with white matter kuru plaques associated with intranuclear inclusion body and argyrophilic grain disease.

Neuropathology 2015 Aug 18;35(4):336-42. Epub 2015 Mar 18.

Institute of Neurology and Austrian Reference Center for Human Prion Diseases, Medical University of Vienna, Vienna, Austria.

We describe an atypical neuropathological phenotype of sporadic Creutzfeldt-Jakob disease in a 76-year-old man. The clinical symptoms were characterized by progressive dementia, gait ataxia, rigidity and urinary incontinence. The disease duration was 6 weeks. Read More

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http://doi.wiley.com/10.1111/neup.12192
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http://dx.doi.org/10.1111/neup.12192DOI Listing
August 2015
9 Reads

Nonconvulsive status epilepticus and Creutzfeldt-Jakob-like EEG changes in a case of lithium toxicity.

Authors:
B K Madhusudhan

Epilepsy Behav Case Rep 2014 28;2:203-5. Epub 2014 Nov 28.

Department of Neurology, M.S. Ramaiah Medical College, New BEL Road, Mathikere, Bangalore -560054, India.

We report a case of a 63-year-old lady with bipolar affective disorder on lithium who was brought to our emergency center in a comatose state. Neurologically, the patient was comatose and had generalized hypotonia and hyporeflexia. Lithium toxicity was considered. Read More

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http://dx.doi.org/10.1016/j.ebcr.2014.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308059PMC
February 2015
3 Reads

Correlates of a single cortical action potential in the epidural EEG.

Neuroimage 2015 Apr 30;109:357-67. Epub 2014 Dec 30.

Neurophysics Group, Department of Neurology, Campus Benjamin Franklin, Charité-Universitätsmedizin Berlin, 12200 Berlin, Germany; Bernstein Center for Computational Neuroscience Berlin, 10115 Berlin, Germany; Bernstein Focus Neurotechnology Berlin, 10587 Berlin, Germany.

To identify the correlates of a single cortical action potential in surface EEG, we recorded simultaneously epidural EEG and single-unit activity in the primary somatosensory cortex of awake macaque monkeys. By averaging over EEG segments coincident with more than hundred thousand single spikes, we found short-lived (≈ 0.5 ms) triphasic EEG deflections dominated by high-frequency components >800 Hz. Read More

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http://dx.doi.org/10.1016/j.neuroimage.2014.12.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349634PMC
April 2015
3 Reads

A study of clinical profile, radiological and electroencephalographic characteristics of suspected Creutzfeldt-Jakob disease in a tertiary care centre in South India.

J Neurosci Rural Pract 2015 Jan;6(1):39-50

Department of Neurology, MS Ramaiah Medical College and Hospital, Bangalore, Karnataka, India.

Introduction: Creutzfeldt-Jakob disease (CJD) is a progressive, fatal, neurodegenerative disease classified under transmissible spongiform encephalopathies (TSE) or prion diseases. It is characterized by long asymptomatic period followed by rapid clinical deterioration leading to the death within months. The disease is still under-reported in India. Read More

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http://search.proquest.com/openview/6baa217449d5bd798bad7e80
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http://www.ruralneuropractice.com/text.asp?2015/6/1/39/14318
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http://dx.doi.org/10.4103/0976-3147.143189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244786PMC
January 2015
13 Reads

Clinical neurophysiological assessment of sepsis-associated brain dysfunction: a systematic review.

Crit Care 2014 Dec 8;18(6):674. Epub 2014 Dec 8.

Department of Intensive Care, Erasme University Hospital, Université Libre de Bruxelles, Route de Lennik 808, 1070, Brussels, Belgium.

Introduction: Several studies have reported the presence of electroencephalography (EEG) abnormalities or altered evoked potentials (EPs) during sepsis. However, the role of these tests in the diagnosis and prognostic assessment of sepsis-associated encephalopathy remains unclear.

Methods: We performed a systematic search for studies evaluating EEG and/or EPs in adult (≥ 18 years) patients with sepsis-associated encephalopathy. Read More

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http://dx.doi.org/10.1186/s13054-014-0674-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277650PMC
December 2014
3 Reads

Electroencephalographic changes in sporadic Creutzfeldt-Jakob disease and correlation with clinical stages: a retrospective analysis.

J Clin Neurophysiol 2014 Dec;31(6):586-93

*Department of Neuroscience, Monash Medical Centre, Clayton, Victoria, Australia; and †Department of Medicine, Monash University, Melbourne, Victoria, Australia.

Purpose: To analyze clinical features and EEG changes in patients with sporadic Creutzfeldt-Jakob disease and study the association between different EEG patterns and clinical stages.

Methods: We retrospectively analyzed the clinical features and EEG patterns of 3 patients with clinical stage II and 10 patients with stage III sporadic Creutzfeldt-Jakob disease (EEG n = 17). Chi-square test was used to study the association between EEG features and disease stages. Read More

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http://dx.doi.org/10.1097/WNP.0000000000000097DOI Listing
December 2014
6 Reads

Significance of triphasic waves in acute encephalopathy.

Authors:
N K Sethi

Eur J Neurol 2014 Nov;21(11):e93

Department of Neurology, New York Presbyterian Hospital, Weill Cornell Medical Center, New York, NY, USA.

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http://dx.doi.org/10.1111/ene.12493DOI Listing
November 2014
8 Reads

Focal triphasic sharp waves and spikes in the electroencephalogram.

Neurol Sci 2015 Feb 26;36(2):221-6. Epub 2014 Aug 26.

Center for Neurology, Fairfax, VA, USA,

There is a plethora of data in the EEG literature on the characteristics of the most prominent component of interictal epileptiform discharges (IED), namely the negative (fast) phase. Surprisingly, however, little attention has been drawn to the after-coming slow wave (ASW), and its pathological as well as clinical significance. In this paper, we will address the significance of prominent (high amplitude) ASW, giving rise to a triphasic morphology of the IED (focal triphasic sharp waves and spikes—FTSW). Read More

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http://www.internationalbrain.org/media/files/files/e799c5b8
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http://link.springer.com/content/pdf/10.1007/s10072-014-1923
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http://link.springer.com/10.1007/s10072-014-1923-1
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http://dx.doi.org/10.1007/s10072-014-1923-1DOI Listing
February 2015
35 Reads
1 Citation
1.500 Impact Factor

Interrater agreement for Critical Care EEG Terminology.

Epilepsia 2014 Sep 2;55(9):1366-73. Epub 2014 Jun 2.

Department of Neurology, Comprehensive Epilepsy Center, Yale University School of Medicine, New Haven, Connecticut, U.S.A.

Objective: The interpretation of critical care electroencephalography (EEG) studies is challenging because of the presence of many periodic and rhythmic patterns of uncertain clinical significance. Defining the clinical significance of these patterns requires standardized terminology with high interrater agreement (IRA). We sought to evaluate IRA for the final, published American Clinical Neurophysiology Society (ACNS)-approved version of the critical care EEG terminology (2012 version). Read More

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http://dx.doi.org/10.1111/epi.12653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879939PMC
September 2014
16 Reads

Application of subhairline EEG montage in intensive care unit: comparison with full montage.

J Clin Neurophysiol 2014 Jun;31(3):181-6

*GE Healthcare Finland Oy, Helsinki, Finland; and Departments of †Anesthesia and Perioperative Medicine, ‡Program in Critical Care, and §Clinical Neurological Science, of Western Ontario, London, Ontario, Canada.

Purpose: Problems with the availability of standard EEG monitoring in the intensive care unit have led to the use of recordings that have limited spatial coverage. We studied the performance of limited coverage EEG compared with more traditional full-montage EEG.

Methods: Continuous EEG recordings were performed on 170 patients using the full-montage 10-20 placement of electrodes as a reference recording and an abbreviated montage of electrodes applied below the hairline (subhairline). Read More

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http://pdfs.journals.lww.com/clinicalneurophys/2014/06000/Ap
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/WNP.0000000000000049DOI Listing
June 2014
9 Reads

Recurring hyperammonemic encephalopathy induced by bacteria usually not producing urease.

BMC Res Notes 2014 May 31;7:324. Epub 2014 May 31.

Institute of Neurology, Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Largo Daneo 3, 16132 Genova, Italy.

Background: Hyperammonemic encephalopathy may occur when urease-positive bacteria in the urinary tract produce ammonium which directly enters systemic circulation. Predisposing conditions such as a neurogenic bladder can increase both urinary tract infection and urine stagnation.

Case Presentation: We describe the case of a 66 years old woman with a neurogenic bladder who twice developed hyperammonemic encephalopathy following urinary tract infection. Read More

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http://dx.doi.org/10.1186/1756-0500-7-324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057615PMC
May 2014
12 Reads

Sporadic Creutzfeldt-Jakob disease (sCJD) with asymmetric findings.

BMJ Case Rep 2014 Mar 24;2014. Epub 2014 Mar 24.

Department of Neurology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.

We report a case of a patient with probable Creutzfeldt-Jakob disease (CJD) who had psychiatric manifestation in the form of withdrawn depressive behaviour at the onset, followed by rapidly progressive ataxia, parkinsonism, mutism and cognitive decline with generalised asynchronous multifocal myoclonic jerks. His EEG exhibited focal (lateralised) periodic triphasic sharp waves on the background of generalised delta slowing, which later on became more generalised. MRI of the brain showed hyperintensity in basal ganglia with cortical ribbon sign in bilateral frontal region. Read More

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http://dx.doi.org/10.1136/bcr-2013-203007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975537PMC
March 2014
7 Reads
1 Citation

Uncovering clinical and radiological associations of triphasic waves in acute encephalopathy: a case-control study.

Authors:
R Sutter P W Kaplan

Eur J Neurol 2014 Apr 10;21(4):660-6. Epub 2014 Feb 10.

Division of Neurosciences Critical Care, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Neurology, Johns Hopkins Bayview Medical Center, Baltimore, MD, USA.

Background And Purpose: Triphasic waves (TWs) are archetypal waveforms seen on electroencephalography (EEG) in some forms of encephalopathy. Their particular underlying pathological substrates are largely unexplored. This case-control study was designed to identify and quantify specific clinical and neuroradiological associations underlying TWs and to determine if TWs predicate outcome. Read More

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http://dx.doi.org/10.1111/ene.12372DOI Listing
April 2014
13 Reads

Ifosfamide related encephalopathy: the need for a timely EEG evaluation.

J Neurol Sci 2014 Jan 16;336(1-2):109-12. Epub 2013 Oct 16.

The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit #431, Room#FC7.3000, Houston, TX 77030-4009, USA.

Background: Ifosfamide is an alkylating agent useful in the treatment of a wide range of cancers including sarcomas, lymphoma, gynecologic and testicular cancers. Encephalopathy has been reported in 10-40% of patients receiving high-dose IV ifosfamide.

Objective: To highlight the role of electroencephalogram (EEG) in the early detection and management of ifosfamide related encephalopathy. Read More

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http://dx.doi.org/10.1016/j.jns.2013.10.018DOI Listing
January 2014
3 Reads

Significance of triphasic waves in patients with acute encephalopathy: a nine-year cohort study.

Clin Neurophysiol 2013 Oct 15;124(10):1952-8. Epub 2013 May 15.

Division of Neurosciences Critical Care, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Objective: Triphasic waves (TWs) are a frequent electroencephalography (EEG) finding in encephalopathy, yet their origin and prognostic significance are not well understood. The aim of this study was to determine the clinical and EEG characteristics in encephalopathic patients with TWs. We hypothesized that specific EEG characteristics are predictive of outcome. Read More

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http://dx.doi.org/10.1016/j.clinph.2013.03.031DOI Listing
October 2013
30 Reads
7 Citations
3.100 Impact Factor

The role of triphasic waves in the care of critically ill patients.

Clin Neurophysiol 2013 Oct 9;124(10):1924. Epub 2013 May 9.

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http://dx.doi.org/10.1016/j.clinph.2013.04.014DOI Listing
October 2013
2 Reads

Typical versus atypical triphasic waves.

J Clin Neurophysiol 2013 Apr;30(2):211

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http://dx.doi.org/10.1097/WNP.0b013e3182872c86DOI Listing
April 2013
2 Reads

Typical versus atypical triphasic morphology waveforms.

Authors:
Nitin K Sethi

J Clin Neurophysiol 2013 Apr;30(2):210-1

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http://dx.doi.org/10.1097/WNP.0b013e3182872aacDOI Listing
April 2013
1 Read

Periodic lateralized triphasic waves in an adult with isolated hemimegalencephaly.

Neurol India 2013 Jan-Feb;61(1):85-6

Department of Neurology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow, Uttar Pradesh, India.

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http://dx.doi.org/10.4103/0028-3886.108024DOI Listing
April 2016
1 Read

[A case of adult-onset type II citrullinemia in an elderly patient].

Nihon Shokakibyo Gakkai Zasshi 2013 Mar;110(3):432-40

Department of Gastroenterology, Chikamori Hospital, Japan.

A 72-year-old man presented with consciousness disturbance. The results of brain magnetic resonance imaging and cerebrospinal fluid examination were normal, but triphasic waves were noted on electroencephalography. His plasma ammonia level was elevated due to which encephalopathy secondary to hyperammonemia was suspected. Read More

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March 2013
3 Reads

Clinical and imaging correlates of EEG patterns in hospitalized patients with encephalopathy.

J Neurol 2013 Apr 30;260(4):1087-98. Epub 2012 Nov 30.

Division of Neurosciences Critical Care, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine and Bayview Medical Center, 301 Mason Lord drive, Suite 2100, Baltimore, MD 21224, USA.

To identify the relationship between pathologic electroencephalographic (EEG) patterns, clinical and neuroradiological abnormalities, and outcome in hospitalized patients with acute encephalopathy. This 5-year cohort study was performed at an academic tertiary care center. EEGs in 154 patients with altered mental status were classified according to five predefined patterns: Isolated continuous slowing of background activity (theta, theta/delta, and delta activity) and patterns with slowing background activity with episodic transients [i. Read More

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http://dx.doi.org/10.1007/s00415-012-6766-1DOI Listing
April 2013
24 Reads
4 Citations
3.380 Impact Factor

Absence of early epileptiform abnormalities predicts lack of seizures on continuous EEG.

Neurology 2012 Oct 10;79(17):1796-801. Epub 2012 Oct 10.

Epilepsy Service, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.

Objective: To determine whether the absence of early epileptiform abnormalities predicts absence of later seizures on continuous EEG monitoring of hospitalized patients.

Methods: We retrospectively reviewed 242 consecutive patients without a prior generalized convulsive seizure or active epilepsy who underwent continuous EEG monitoring lasting at least 18 hours for detection of nonconvulsive seizures or evaluation of unexplained altered mental status. The findings on the initial 30-minute screening EEG, subsequent continuous EEG recordings, and baseline clinical data were analyzed. Read More

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http://dx.doi.org/10.1212/WNL.0b013e3182703fbcDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475619PMC
October 2012
3 Reads

Pregabalin intoxication-induced encephalopathy with triphasic waves.

Authors:
Sejin Lee

Epilepsy Behav 2012 Oct 29;25(2):170-3. Epub 2012 Sep 29.

Department of Neurology, Yeungnam University College of Medicine, Daegu, Republic of Korea.

This report documents the case of a 79-year-old woman presenting with encephalopathy and triphasic waves (TWs) due to pregabalin (PGB) intoxication. For the two years prior to admission, she had taken PGB to treat post-herpetic neuralgia. Brain MRI revealed mild leukoaraiosis and cortical atrophy. Read More

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http://dx.doi.org/10.1016/j.yebeh.2012.08.002DOI Listing
October 2012
2 Reads

Comparison of triphasic waves and epileptic discharges in one patient with genetic epilepsy.

J Clin Neurophysiol 2012 Oct;29(5):458-61

Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Genetic epilepsies with generalized spike-wave complexes (GSWCs) and encephalopathy triphasic waves (TWs) may resemble each other and have three phases per complex. Electroencephalographic (EEG) interpretation is subjective, and EEGers have noted "TWs" in cases labeled nonconvulsive status epilepticus (NCSE). Direct comparison of both wave forms under the same conditions is rarely possible. Read More

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http://pdfs.journals.lww.com/clinicalneurophys/2012/10000/Co
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http://dx.doi.org/10.1097/WNP.0b013e31826bde70DOI Listing
October 2012
12 Reads

Portosystemic shunts: an underdiagnosed but treatable cause of neurological and psychiatric disorders.

J Neurol Sci 2012 Oct 17;321(1-2):58-64. Epub 2012 Aug 17.

Department of Neurology, Salpêtrière Hospital, Assistance Publique Hôpitaux de Paris, France.

Portosystemic shunts (PSS) remain an unrecognized cause of neurological or psychiatric disorders. Here we report 5 patients with neuropsychiatric presentations of PSS. Main presentations encompassed progressive Parkinsonism, organic psychosis, recurrent coma, recurrent delusion, cognitive decline and posterior cortical atrophy. Read More

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http://dx.doi.org/10.1016/j.jns.2012.07.050DOI Listing
October 2012
4 Reads

Carcinomatous meningitis: Yet another cause for rapidly progressive dementia and triphasic waves in electroencephalograph!

J Neurosci Rural Pract 2012 May;3(2):207-9

Department of Neurology, NIMHANS, Bangalore, India.

We report a 65-year-old woman who manifested with progressive cognitive impairment, abnormal behavior, slurred speech, inability to carry out activities with right upper limb, gait disturbances, emotional liability, and double incontinence that evolved progressively over the last 8 months. A clinical syndrome of "rapidly progressive dementia" was considered. The MRI of brain was unremarkable except for small para third ventricular enhancing lesion was detected in the left thalamic region. Read More

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http://dx.doi.org/10.4103/0976-3147.98253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410003PMC
May 2012
5 Reads

Isolated ACTH deficiency presenting with a glucocorticoid-responsive triphasic wave coma.

Intern Med 2012 15;51(14):1913-5. Epub 2012 Jul 15.

Department of Neurology, Tokyo Rosai Occupational Diseases and Injuries Hospital, Japan.

We report the case of a 58-year-old woman who presented with acutely developed coma characterized by electroencephalographic triphasic waves (TWs) in the absence of metabolic derangement. The patient's coma and TWs were promptly resolved after the administration of glucocorticoids, and thereafter isolated ACTH deficiency was diagnosed. Isolated ACTH deficiency may present with glucocorticoid-responsive acute encephalopathy without hypoglycemia, hyponatremia, or systemic hypotension. Read More

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January 2013
5 Reads