1,871 results match your criteria Dysthymic Disorder


Associated factors for depressive disorder in patients with end-stage renal disease treated with continuous ambulatory peritoneal dialysis.

Ther Clin Risk Manag 2019 1;15:541-548. Epub 2019 Apr 1.

Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand,

Background: The aim of this study was to primarily determine factors associated with the depressive disorders in continuous ambulatory peritoneal dialysis (CAPD).

Methods: CAPD patients were recruited from the chronic kidney disease and CAPD Clinic of University Hospital. The stable CAPD patients for at least 3 months were included in the study. Read More

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http://dx.doi.org/10.2147/TCRM.S186394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448535PMC

Toward a neurobehavioral trait conceptualization of depression proneness.

Psychophysiology 2019 Apr 5:e13367. Epub 2019 Apr 5.

Department of Psychology, Florida State University, Tallahassee, Florida.

The etiology of major depressive disorder is heterogeneous, and differing pathways leading to the development of depression are proposed to account for alternative variants of depressive illness and their distinct comorbidity patterns. The present study was undertaken as a step toward developing a model for conceptualizing and quantifying dispositional proneness to depression, marked by reduced neural sensitivity to rewarding events and more persistent occurrence of depressive symptomatology. Using data for college and community adult participants (N = 201), we sought to quantify variations in depression proneness by combining symptom indicators of persistent depressive conditions (dysthymic disorder, depressive personality) with a brain potential response that has been shown to index sensitivity to pleasurable events-the reward positivity (RewP; Proudfit, 2015). Read More

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http://dx.doi.org/10.1111/psyp.13367DOI Listing
April 2019
2 Reads

Development and validation of the 22-item Tarumi's modern-type depression trait scale; Avoidance of social roles, Complaint and low Self-esteem (TACS-22).

Psychiatry Clin Neurosci 2019 Mar 21. Epub 2019 Mar 21.

Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Aim: Understanding premorbid personality is important especially when considering treatment selection. Historically, the premorbid personality of Japan's depression is Shuchaku-kishitsu, proposed by Shimoda in the 1930s. Since around 2000, young adults with depression who have premorbid personality differing from the traditional type have increasingly been reported in Japan. Read More

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http://dx.doi.org/10.1111/pcn.12842DOI Listing
March 2019
2 Reads

Prevalence of depression among Iranian patients with rheumatoid arthritis: a systematic review and meta-analysis.

Open Access Rheumatol 2019 13;11:53-59. Epub 2019 Feb 13.

Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde, Glasgow, UK.

Patients with rheumatoid arthritis (RA) are prone to depression due to several factors related to their RA, including chronic and persistent pain, functional disability, economic constraints, and the side effects of RA medication. Previous Iranian studies showed conflicting and inconclusive findings regarding the prevalence of depression among RA patients. Therefore, this systematic review and meta-analysis was conducted to estimate the true prevalence of depression in Iranian patients with RA. Read More

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https://www.dovepress.com/prevalence-of-depression-among-ira
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http://dx.doi.org/10.2147/OARRR.S191459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388731PMC
February 2019
7 Reads

Evaluation of the effect of insulin sensitivity-enhancing lifestyle- and dietary-related adjuncts on antidepressant treatment response: protocol for a systematic review and meta-analysis.

Syst Rev 2019 Feb 25;8(1):62. Epub 2019 Feb 25.

School of Pharmacy, Royal College of Surgeons in Ireland (RCSI), 123, St Stephen's Green, Dublin 2, Ireland.

Background: Depression is the leading cause of disability worldwide and is known to be associated with insulin resistance (IR). Insulin resistance worsens the symptoms of depression and reduces the effectiveness of antidepressant medications in some depressed patients. Many studies have assessed the effect of adjunctive exercise, vitamin D supplementation, zinc supplementation, magnesium, probiotics, unsaturated fatty acids, and hygienic-dietary recommendations (sleep hygiene, healthy diet, physical activity, and sunlight exposure, combined or singly used), individually, on antidepressant treatment response. Read More

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http://dx.doi.org/10.1186/s13643-019-0978-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388470PMC
February 2019
6 Reads

Frequency of mental disorders among chronic pain patients with or without fibromyalgia in Japan.

Neuropsychopharmacol Rep 2018 Dec 11;38(4):167-174. Epub 2018 Aug 11.

Department of Psychiatry, Osaka University Graduate School of Medicine, Osaka, Japan.

Aim: To explore the characteristics of psychiatric morbidity in chronic pain patients who present with or without fibromyalgia.

Methods: Patients are referred to our chronic pain clinic from primary medical institutions, as we are a secondary medical institution. Although some patients have chronic pain, they have no clear organic disorder such as rheumatoid arthritis to account for the pain. Read More

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http://doi.wiley.com/10.1002/npr2.12025
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http://dx.doi.org/10.1002/npr2.12025DOI Listing
December 2018
18 Reads

Citing Hippocrates on depression in epilepsy.

Authors:
Christian Hoppe

Epilepsy Behav 2019 Jan 27;90:31-36. Epub 2018 Nov 27.

Department of Epileptology, University of Bonn Medical Centre, Sigmund-Freud-Strasse 25, FRG-53127 Bonn, Germany. Electronic address:

Objectives: When writing about the bidirectional etiological relationship between depression and epilepsy, neuropsychiatrists often cite Lewis (1934) [Lewis AJ. Melancholia: a historical review. Journal of Mental Science 1934; 80: 1-42] who cited Hippocrates - namely, "melancholics ordinarily become epileptics, and epileptics, melancholics". Read More

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http://dx.doi.org/10.1016/j.yebeh.2018.10.041DOI Listing
January 2019
18 Reads

Incident Chronic Spinal Pain and Depressive Disorders: Data From the National Comorbidity Survey.

J Pain 2019 Apr 22;20(4):481-488. Epub 2018 Nov 22.

Washington State University, Vancouver, Washington.

This study examined pre-existing depression as a risk factor for the development of chronic spinal pain, and pre-existing chronic spinal pain as a risk factor for the development of depression. Data from the National Comorbidity Survey, a stratified sample of 5,001 participants evaluated in 1990 to 1992 (NCS-1) and again in 2000 to 2001 (NCS-2) were used to address these associations. Cox regression was used to estimate hazard ratios and time-to-incidence after NCS-1. Read More

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http://dx.doi.org/10.1016/j.jpain.2018.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433529PMC
April 2019
11 Reads

[Prevalence of bipolar spectrum disorders in migraine patients].

Agri 2018 Oct;30(4):189-198

Department of Psychology, Üsküdar University Faculty of Humanities and Social Sciences, Istanbul, Turkey.

Objectives: Comorbidity of migraine and mood disorders has long been recognized. Most of the studies have focused on the relationship between migraine and major depression with only few studies suggesting a special association between migraine and bipolar spectrum disorders. We aimed to evaluate the prevalence of bipolar disorder in migraine patients in a specialized headache outpatient clinic. Read More

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http://dx.doi.org/10.5505/agri.2018.02439DOI Listing
October 2018
26 Reads

Predicting the naturalistic course of depression from a wide range of clinical, psychological, and biological data: a machine learning approach.

Transl Psychiatry 2018 11 5;8(1):241. Epub 2018 Nov 5.

Department of Psychiatry and Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.

Many variables have been linked to different course trajectories of depression. These findings, however, are based on group comparisons with unknown translational value. This study evaluated the prognostic value of a wide range of clinical, psychological, and biological characteristics for predicting the course of depression and aimed to identify the best set of predictors. Read More

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http://www.nature.com/articles/s41398-018-0289-1
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http://dx.doi.org/10.1038/s41398-018-0289-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218451PMC
November 2018
22 Reads

Differences between chronic and nonchronic depression: Systematic review and implications for treatment.

Depress Anxiety 2019 01 9;36(1):18-30. Epub 2018 Oct 9.

Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany.

Background: There is still uncertainty if and to what extent chronic depression (CD) presents with specific features especially in contrast to the nonchronic course of major depressive disorder (non-CD). This systematic review aims to summarize the existing literature regarding sociodemographic factors, psychopathology, and course of disease in patients with CD in comparison to patients with non-CD.

Methods: A structured database search (MEDLINE, PsycINFO, Web of Science, CENTRAL) was performed. Read More

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http://doi.wiley.com/10.1002/da.22835
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http://dx.doi.org/10.1002/da.22835DOI Listing
January 2019
11 Reads

Course and stability of cognitive and metacognitive beliefs in depression.

Depress Anxiety 2018 12 12;35(12):1239-1246. Epub 2018 Sep 12.

Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Maladaptive cognitive beliefs as measured by the Dysfunctional Attitudes Scale (DAS) increase vulnerability to depression. Maladaptive metacognitive beliefs as measured by the Metacognitive Questionnaire-30 (MCQ-30) are also thought to contribute to depression. However, the long-term stability of metacognitive beliefs in depression has not yet been investigated. Read More

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http://dx.doi.org/10.1002/da.22834DOI Listing
December 2018
5 Reads

Persistent depressive disorder has long-term negative impacts on depression, anxiety, and somatic symptoms at 10-year follow-up among patients with major depressive disorder.

J Affect Disord 2019 01 18;243:255-261. Epub 2018 Sep 18.

Department of Nursing, Mackay Medical College, Taiwan.

Objective: The study aimed to investigate the impacts of persistent depressive disorder (PDD) and pharmacotherapy on depression, anxiety, and somatic symptoms among patients with major depressive disorder (MDD) over a ten-year period.

Methods: 290 outpatients with MDD were enrolled, including 117 with PDD, at baseline. Subjects were followed-up at six-month, two-year, and 10-year points. Read More

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http://dx.doi.org/10.1016/j.jad.2018.09.068DOI Listing
January 2019
13 Reads

Social cognitive abilities predict psychosocial dysfunction in major depressive disorder.

Depress Anxiety 2019 01 13;36(1):54-62. Epub 2018 Sep 13.

Department of Psychiatry, Melbourne Medical School, University of Melbourne, Melbourne, VIC, Australia.

Background: Major depressive disorder (MDD) is associated with social cognitive deficits (e.g., poor affect recognition and impaired theory of mind). Read More

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http://doi.wiley.com/10.1002/da.22844
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http://dx.doi.org/10.1002/da.22844DOI Listing
January 2019
11 Reads

Moderating effect of comorbid anxiety disorders on treatment outcome in a randomized controlled psychotherapy trial in early-onset persistently depressed outpatients.

Depress Anxiety 2018 10 10;35(10):1001-1008. Epub 2018 Sep 10.

Department of Psychiatry and Psychotherapy, Lübeck University, Lübeck, Germany.

Background: Persistent depressive disorder (PDD) is associated with high rates of comorbid psychiatric disorders, mostly anxiety disorders (ADs). Comorbid AD was found to be associated with poorer treatment outcome in PDD patients. The effect of comorbid AD on disorder-specific treatment for PDD (Cognitive Behavioral Analysis System of Psychotherapy [CBASP]) has not been studied yet. Read More

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http://dx.doi.org/10.1002/da.22839DOI Listing
October 2018
6 Reads

Depression Plays a Moderating Role in the Cognitive Decline Associated With Changes of Brain White Matter Hyperintensities.

J Clin Psychiatry 2018 Sep 4;79(5). Epub 2018 Sep 4.

Department of Neuropsychiatry, Seoul National University Bundang Hospital, 300 Gumidong, Bundanggu, Seongnamsi, Gyeonggi-do, Korea 463-707.

Objective: In the elderly, depression and white matter hyperintensities (WMH) are common and associated with cognitive impairment. This study investigated the possible interactions between depression and WMH in their influences on cognition of the elderly.

Methods: Using multiple neuropsychological tests, we evaluated the cognitive function of 122 community-dwelling elders with depression at baseline between November 2008 and February 2009. Read More

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https://www.psychiatrist.com/JCP/article/Pages/2018/v79/17m1
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http://dx.doi.org/10.4088/JCP.17m11763DOI Listing
September 2018
122 Reads

Course of subthreshold depression into a depressive disorder and its risk factors.

J Affect Disord 2018 12 9;241:206-215. Epub 2018 Aug 9.

Netherlands Institute of Mental Health and Addiction, Utrecht, The Netherlands.

Background: Information on the natural course of subthreshold depression and risk factors for the development of a full-blown depressive disorder in the general population is scarce. This information is crucial to understand the development of depression and to advance indicated depression prevention.

Methods: Using longitudinal data from a representative population-based study (the Netherlands Mental Health Survey and Incidence Study-2) we assessed 3-year course of subthreshold depression (depressive symptoms causing clinically significant distress for at least 2 weeks, or for 3 days per month for a year; n = 120), compared to an asymptomatic group (n = 4111) and a depressive disorder group (major depression or dysthymia; n = 294). Read More

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http://dx.doi.org/10.1016/j.jad.2018.08.010DOI Listing
December 2018
6 Reads

Clinical and radiological characteristics of early versus late mild cognitive impairment in patients with comorbid depressive disorder.

Int J Geriatr Psychiatry 2018 12 23;33(12):1604-1612. Epub 2018 Jul 23.

Columbia University, New York, NY, USA.

Objective: The classification of mild cognitive impairment (MCI) continues to be debated though it has recently been subtyped into late (LMCI) versus early (EMCI) stages. Older adults presenting with both a depressive disorder (DEP) and cognitive impairment (CI) represent a unique, understudied population. Our aim was to examine baseline characteristics of DEP-CI patients in the DOTCODE trial, a randomized controlled trial of open antidepressant treatment for 16 weeks followed by add-on donepezil or placebo for 62 weeks. Read More

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http://dx.doi.org/10.1002/gps.4955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246783PMC
December 2018
12 Reads

CBT and positive psychology interventions for clinical depression promote healthy attentional biases: An eye-tracking study.

Depress Anxiety 2018 10 20;35(10):966-973. Epub 2018 Jul 20.

Department of Psychology, Faculty of Health Sciences, Francisco de Vitoria University, Madrid, Spain.

Background: Although there is a growing interest in the role of attentional biases in depression, there are no studies assessing changes in these biases after psychotherapeutic interventions.

Methods: We used a validated eye-tracking procedure to assess pre-post therapy changes in attentional biases toward emotional information (i.e. Read More

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http://dx.doi.org/10.1002/da.22786DOI Listing
October 2018
2 Reads

Prevalence of Childhood Affective disorders in Turkey: An epidemiological study.

Authors:
Gul Karacetin Ayse Rodopman Arman Nese Perdahli Fis Esra Demirci Sevgi Ozmen Selma Tural Hesapcioglu Didem Oztop Ali Evren Tufan Umit Tural Evrim Aktepe Hatice Aksu Ulku Akyol Ardic Senem Basgul Oznur Bilac Murat Coskun Gonca Gul Celik Sevcan Karakoc Demirkaya Onur Burak Dursun Ibrahim Durukan Tulin Fidan Salih Gencoglan Cem Gokcen Emel Sari Gokten Isık Gorker Vahdet Gormez Ozlem Yildiz Gundogdu Cihat Kagan Gurkan Sabri Herguner Hasan Kandemir Birim Gunay Kilic Ayse Kilincaslan Tuba Mutluer Serhat Nasiroglu Ozlem Ozel Ozcan Mucahit Ozturk Sermin Yalin Sapmaz Serkan Suren Nilfer Sahin Aysegul Yolga Tahiroglu Fevziye Toros Fatih Unal Pinar Vural Ipek Percinel Yazici Kemal Utku Yazici Veli Yildirim Yasemin Yulaf Murat Yuce Tugba Yuksel Devrim Akdemir Hatice Altun Basak Ayik Ayhan Bilgic Ozlem Hekim Bozkurt Emine Demirbas Cakir Veysi Ceri Nagehan Ucok Demir Gulser Dinc Mustafa Yasin Irmak Dursun Karaman Mehmet Fatih Kinik Betul Mazlum Nursu Cakin Memik Dilsad Foto Ozdemir Hayati Sinir Bedia Ince Tasdelen Beril Taskin Cagatay Ugur Pınar Uran Taciser Uysal Ozden Sukran Uneri Savas Yilmaz Sultan Seval Yilmaz Burak Acikel Huseyin Aktas Rumeysa Alaca Betul Gul Alic Mahmoud Almbaidheen Fatma Pinar Ari Cihan Aslan Ender Atabay Merve Gunay Ay Hilal Aydemir Gülseda Ayranci Zehra Babadagi Hasan Bayar Pelin Con Bayhan Ozlem Bayram Nese Dikmeer Bektas Kivanc Kudret Berberoglu Recep Bostan Yasemin Cakan Merve Arici Canli Mehmet Akif Cansiz Cansin Ceylan Nese Coskun Seyma Coskun Ibrahim Demir Nuran Demir Esen Yildirim Demirdogen Busra Dogan Yunus Emre Donmez Funda Donder Aysegul Efe Safak Eray Seda Erbilgin Semih Erden Elif Gokce Ersoy Tugba Eseroglu Sumeyra Kina Firat Ezgi Eynalli Gok Seyda Celik Goksoy Gulen Guler Zafer Gules Gulay Gunay Serkan Gunes Adem Gunes Gokcen Guven Havvana Horozcu Ayse Irmak Umit Isik Ozlem Kahraman Bilge Merve Kalayci Umut Karaaslan Mehmet Karadag Hilal Tugba Kilic Fethiye Kilicaslan Duygu Kinay Esra Bulanik Koc Omer Kocael Rahime Kadir Mutlu Zejnep San Kevser Nalbant Nilufer Okumus Fatih Ozbek Fatma Akkus Ozdemir Hanife Ozdemir Borte Gurbuz Ozgur Selcuk Ozkan Esra Yildirim Ozyurt Berna Polat Hatice Polat Ebru Sekmen Mehmet Sertcelik Feyza Hatice Sevgen Oguz Sevince Ulker Shamkhalova Funda Suleyman Nurcan Eren Simsek Yasar Tanir Mehmet Tekden Seyhan Temtek Melike Topal Zehra Topal Tugba Turk Halit Necmi Ucar Filiz Ucar Duygu Uygun Necati Uzun Zeynep Vatansever Neslihan Gokce Yazgili Dilsad Miniksar Yildiz Nazike Yildiz Eyup Sabri Ercan

J Affect Disord 2018 10 30;238:513-521. Epub 2018 May 30.

Ege University Faculty of Medicine, Department of Child and Adolescent Psychiatry, Izmir, Turkey. Electronic address:

Aim: To determine the prevalence of affective disorders in Turkey among a representative sample of Turkish population.

Methods: This study was conducted as a part of the "The Epidemiology of Childhood Psychopathology in Turkey" (EPICPAT-T) Study, which was designed by the Turkish Association of Child and Adolescent Mental Health. The inclusion criterion was being a student between the second and fourth grades in the schools assigned as study centers. Read More

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http://dx.doi.org/10.1016/j.jad.2018.05.014DOI Listing
October 2018
23 Reads
3.383 Impact Factor

The ICD-11 developmental field study of reliability of diagnoses of high-burden mental disorders: results among adult patients in mental health settings of 13 countries.

World Psychiatry 2018 Jun;17(2):174-186

Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA.

Reliable, clinically useful, and globally applicable diagnostic classification of mental disorders is an essential foundation for global mental health. The World Health Organization (WHO) is nearing completion of the 11th revision of the International Classification of Diseases and Related Health Problems (ICD-11). The present study assessed inter-diagnostician reliability of mental disorders accounting for the greatest proportion of global disease burden and the highest levels of service utilization - schizophrenia and other primary psychotic disorders, mood disorders, anxiety and fear-related disorders, and disorders specifically associated with stress - among adult patients presenting for treatment at 28 participating centers in 13 countries. Read More

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http://dx.doi.org/10.1002/wps.20524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980511PMC
June 2018
27 Reads
1 Citation
14.220 Impact Factor

Prevalence of anxiety and depressive disorders among youth with intellectual disabilities: A systematic review and meta-analysis.

J Affect Disord 2018 08 6;236:230-242. Epub 2018 Apr 6.

Department of Psychoeducation and Psychology, Université du Québec en Outaouais (UQO), Saint-Jérôme, Canada; School of Public Health, Department of Social and Preventive Medicine, Université de Montréal, Montréal, Canada; Research Center, Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Nord-de-l'Île-de-Montréal, Montréal, Canada.

Background: The purpose of this meta-analytic study was to determine the pooled prevalence estimates of anxiety and depressive disorders among children and adolescents with intellectual disabilities (ID) and to assess the extent to which these pooled prevalence rates differed according to studies' characteristics.

Method: A systematic literature search was performed in nine databases and 21 studies, published between 1975 and 2015, met the inclusion criteria.

Results: The resulting pooled prevalence estimates of combined subtypes of anxiety and depressive disorders were respectively (a) 5. Read More

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http://dx.doi.org/10.1016/j.jad.2018.04.029DOI Listing
August 2018
13 Reads

The Role of Self-Esteem in Depression: A Longitudinal Study.

Behav Cogn Psychother 2019 Mar 25;47(2):244-250. Epub 2018 Apr 25.

Department of Psychological Methodology and Assessment,Ludwig-Maximilians-University,Munich,Germany.

Background: Based on the vulnerability model, several studies indicate that low self-esteem seems to contribute to depressive symptoms.

Aims: The aim of this study was to treat depressive symptoms in a cognitive behavioural group therapy, focusing on the enhancement of self-esteem, and to explore co-variation in depressive symptoms and the level of self-esteem.

Method: The Multidimensional Self-esteem Scale (MSWS) and the Beck Depression Inventory (BDI) were administered to 147 psychiatric in-patients with current depressive symptoms due to an affective disorder (major depression, bipolar I, dysthymia). Read More

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http://dx.doi.org/10.1017/S1352465818000243DOI Listing
March 2019
4 Reads

Characterizing anxiety subtypes and the relationship to behavioral phenotyping in major depression: Results from the EMBARC study.

J Psychiatr Res 2018 Jul 6;102:207-215. Epub 2018 Apr 6.

The University of Texas Southwestern Medical Center, Department of Psychiatry, Center for Depression Research and Clinical Care, Department of Psychiatry, Dallas, TX, USA. Electronic address:

The current study aimed to characterize the multifaceted nature of anxiety in patients with major depression by evaluating distinct anxiety factors. We then related these derived anxiety factors to performance on a Flanker Task of cognitive control, in order to further validate these factors. Data were collected from 195 patients with nonpsychotic chronic or recurrent major depression or dysthymic disorder. Read More

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http://dx.doi.org/10.1016/j.jpsychires.2018.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097520PMC
July 2018
23 Reads

Antidepressants for the treatment of depression in people with cancer.

Cochrane Database Syst Rev 2018 04 23;4:CD011006. Epub 2018 Apr 23.

​Department of Neuroscience, Biomedicine and Movement Sciences, Section of Psychiatry, University of Verona, Policlinico "GB Rossi", Piazzale L.A. Scuro, 10, Verona, Italy, 37134.

Background: Major depression and other depressive conditions are common in people with cancer. These conditions are not easily detectable in clinical practice, due to the overlap between medical and psychiatric symptoms, as described by diagnostic manuals such as the Diagnostic and Statistical Manual of Mental Disorders (DSM) and International Classification of Diseases (ICD). Moreover, it is particularly challenging to distinguish between pathological and normal reactions to such a severe illness. Read More

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http://dx.doi.org/10.1002/14651858.CD011006.pub3DOI Listing
April 2018
13 Reads

Emerging psychiatric disorders in Kleine-Levin syndrome.

J Sleep Res 2018 Oct 14;27(5):e12690. Epub 2018 Apr 14.

National Reference Centre for Narcolepsy, Hypersomnia and Kleine-Levin Syndrome, Pitie-Salpetriere University Hospital, AP-HP, Paris, France.

In Kleine-Levin syndrome (KLS), episodes of hypersomnia and cognitive, psychiatric and behavioural disturbances alternate with asymptomatic periods in adolescents. We evaluated whether psychiatric disorders would emerge during asymptomatic periods in a naturalistic, uncontrolled clinical cohort. Patients with primary KLS underwent psychiatric interviews at diagnosis and every year for 1-10 years, leading to diagnosis of former and present comorbid psychiatric disorders. Read More

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http://dx.doi.org/10.1111/jsr.12690DOI Listing
October 2018
11 Reads

The association between lifetime cannabis use and dysthymia across six birth decades.

J Affect Disord 2018 07 16;234:327-334. Epub 2018 Mar 16.

Lev Hasharon Medical Center, Israel; Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: Though high rates of co-occurring cannabis use and depression are well-documented, data regarding the association between cannabis use and dysthymia is scarce. The aim of this cross-sectional study was to explore clinical correlations of cannabis use among individuals with dysthymia, as well as the changes in the association between cannabis use and dysthymia across six decades of birth cohorts.

Methods: Data were drawn from the National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III; 2012-2013; N = 36,309). Read More

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http://dx.doi.org/10.1016/j.jad.2018.03.005DOI Listing
July 2018
9 Reads

Obsessive-compulsive disorder and the risk of subsequent mental disorders: A community study of adolescents and young adults.

Depress Anxiety 2018 04 28;35(4):339-345. Epub 2018 Feb 28.

Division of Clinical Psychology and Epidemiology, Department of Psychology, University of Basel, Basel, Switzerland.

Background: Comorbidity of obsessive-compulsive disorder (OCD) with other mental disorders has been demonstrated repeatedly. Few longitudinal studies, however, have evaluated the temporal association of prior OCD and subsequent mental disorders across the age period of highest risk for first onset of mental disorders. We examined associations between prior OCD and a broad range of subsequent mental disorders and simulated proportions of new onsets of mental disorders that could potentially be attributed to prior OCD, assuming a causal relationship. Read More

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http://doi.wiley.com/10.1002/da.22733
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http://dx.doi.org/10.1002/da.22733DOI Listing
April 2018
11 Reads

Antidepressant effects of dammarane sapogenins in chronic unpredictable mild stress-induced depressive mice.

Phytother Res 2018 Jun 22;32(6):1023-1029. Epub 2018 Feb 22.

Research Center for Pharmacology and Toxicology, Institute of Medicinal Plant Development (IMPLAD), Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100006, China.

Depression is a common, dysthymic, and psychiatric disorder, resulting in enormous social and economic burden. Dammarane sapogenins (DS), an active fraction from oriental ginseng, has shown antidepressant-like effects in chronic restraint rats and sleep interruption-induced mice, and the present study aimed to further confirm the antidepressant effects of DS in a model of chronic unpredictable mild stress (CUMS) and to explore the underlying mechanism. Oral administration of DS (20, 40, and 80 mg/kg) markedly improved depressant-like behaviors, increasing the sucrose intake in the sucrose preference test and reducing the latency in the novelty-suppressed feeding test, and decreasing the immobility time in both the tail suspension and forced swimming tests, compared with the CUMS mice. Read More

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http://dx.doi.org/10.1002/ptr.6040DOI Listing
June 2018
23 Reads

Awareness of Medical Fitness to Drive Guidelines among Occupational Physicians and Psychiatrists.

Ir Med J 2017 Dec 18;110(10):653. Epub 2017 Dec 18.

National Office for Traffic Medicine, Royal College of Physicians of Ireland, Dublin 2.

Irrespective of national guidelines for medical fitness to drive, this study investigated the cumulative expert wisdom of clinicians regarding minimum periods of driving cessation required for patients suffering from conditions that can impair driver capability. Occupational Physicians (196) and Psychiatrists (103) completed an online questionnaire. For private motorists, the modal response for anxiety and depression favoured clinical discretion, followed by three month cessations for hypomania, acute psychosis, schizophrenia and alcohol dependence and six weeks for alcohol misuse/dependence. Read More

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December 2017
3 Reads

Mood disorders in familial epilepsy: A test of shared etiology.

Epilepsia 2018 02 10;59(2):431-439. Epub 2018 Jan 10.

Department of Genetics, Human Genetics Institute of New Jersey, Rutgers, State University of New Jersey, Piscataway, NJ, USA.

Objective: Mood disorders are the most common comorbid conditions in epilepsy, but the cause remains unclear. One possible explanation is a shared genetic susceptibility to epilepsy and mood disorders. We tested this hypothesis by evaluating lifetime prevalence of mood disorders in relatives with and without epilepsy in families containing multiple individuals with epilepsy, and comparing the findings with rates from a general population sample. Read More

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http://dx.doi.org/10.1111/epi.13985DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803440PMC
February 2018
6 Reads

Clinical and Genetic Predictors of Delayed Remission After Multiple Levels of Antidepressant Treatment: Toward Early Identification of Depressed Individuals for Advanced Care Options.

J Clin Psychiatry 2017 Nov/Dec;78(9):e1291-e1298

Department of Psychiatry, The University of Alabama, Birmingham, Alabama, USA.

Objective: To identify clinical and genetic characteristics that can be used to recognize depressed patients who are likely to respond quickly versus those who will have a more delayed response following multiple treatment trials.

Methods: The data used were obtained from the National Institute of Mental Health-sponsored Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study, which was conducted between July 2001 and September 2006. Of the 4,041 treatment-naive participants in the original study, 1,953 with DNA samples were included. Read More

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http://dx.doi.org/10.4088/JCP.17m11448DOI Listing
April 2019
19 Reads

Comorbidity of narcolepsy and depressive disorders: a nationwide population-based study in Taiwan.

Sleep Med 2017 Nov 5;39:95-100. Epub 2017 Sep 5.

Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Department of Chinese Medicine, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan, Taiwan. Electronic address:

Objective: Narcolepsy is a chronic sleep disorder that is likely to have neuropsychiatric comorbidities. Depression is a serious mood disorder that affects individuals' daily activities and functions. The current study aimed to investigate the relationship between narcolepsy and depressive disorders. Read More

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http://dx.doi.org/10.1016/j.sleep.2017.07.022DOI Listing
November 2017
11 Reads

Pattern of Changes during Treatment: A Comparison between a Positive Psychology Intervention and a Cognitive Behavioral Treatment for Clinical Depression.

Span J Psychol 2017 Oct 26;20:E52. Epub 2017 Oct 26.

Universidad Complutense (Spain).

Research on psychotherapy has traditionally focused on analyzing changes between the beginning and the end of a treatment. Few studies have addressed the pattern of therapeutic change during treatment. The aim of this study was to examine the pattern of changes in clinical and well-being variables during a cognitive behavioral therapy (CBT) program compared with an integrative positive psychology interventions program for clinical depression IPPI-D. Read More

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http://dx.doi.org/10.1017/sjp.2017.44DOI Listing
October 2017
7 Reads

Clinical characteristics of patients with diagnostic uncertainty of major depressive disorder.

Asian J Psychiatr 2017 Dec 16;30:159-162. Epub 2017 Oct 16.

Department of Psychiatry, National Defense Medical College, Saitama, Japan. Electronic address:

Background: Physicians do not always confidently diagnose psychiatric disorders. The present study was conducted to identify the clinical characteristics of patients in whom a definitive diagnosis of major depressive disorder (MDD) could not be established.

Methods: The participants were 199 consecutive outpatients with MDD, who were comprehensively diagnosed using the Mini International Neuropsychiatric Interview (MINI). Read More

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http://dx.doi.org/10.1016/j.ajp.2017.10.001DOI Listing
December 2017
11 Reads

Differences in the association between persistent pathogens and mood disorders among young- to middle-aged women and men in the U.S.

Brain Behav Immun 2018 02 28;68:56-65. Epub 2017 Sep 28.

Department of Global Health and Social Medicine, King's College London, London, UK; Department of Epidemiology and Biostatistics, CUNY Graduate School of Public Health and Health Policy, New York, NY, United States.

Background: A growing literature supports the role of immune system alterations in the etiology of mood regulation, yet there is little population-based evidence regarding the association between persistent pathogens, inflammation and mood disorders among younger women and men in the U.S.

Methods: We used data from the National Health and Nutrition Examination Survey III on individuals 15-39 years of age assessed for major depression, dysthymia, and/or bipolar disorder I and tested for cytomegalovirus (N=6825), herpes simplex virus (HSV)-1 (N=5618) and/or Helicobacter pylori (H. Read More

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http://dx.doi.org/10.1016/j.bbi.2017.09.017DOI Listing
February 2018
6 Reads

Multimorbidity is associated with increased rates of depression in patients hospitalized with diabetes mellitus in the United States.

J Diabetes Complications 2017 Nov 4;31(11):1571-1579. Epub 2017 Aug 4.

Department of Family and Community Medicine, Baylor College of Medicine, 3701 Kirby Dr., Suite 600 (MS: BCM700), Houston, TX 77098, USA.

Aims: Information on the burden and risk factors for diabetes-depression comorbidity in the US is sparse. We used data from the largest all-payer, nationally-representative inpatient database in the US to estimate the prevalence, temporal trends, and risk factors for comorbid depression among adult diabetic inpatients.

Methods: We conducted a retrospective analysis using the 2002-2014 Nationwide Inpatient Sample databases. Read More

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http://dx.doi.org/10.1016/j.jdiacomp.2017.08.001DOI Listing
November 2017
23 Reads
1.925 Impact Factor

The prevalence of depression in rheumatoid arthritis in China: A systematic review.

Oncotarget 2017 Aug 21;8(32):53623-53630. Epub 2017 Apr 21.

Children's Research Institute, Children's National Medical Center, Washington, DC, USA.

This systematic review is to explore the prevalence of depression in patients with rheumatoid arthritis (RA) in China. Articles of prevalence rates for depression in adult RA patients published before October 2015 were identified from PubMed, Embase, The Cochrane Library, CNKI, CBM, VIP, and Wanfang database and other internet databases. Relevant journals and the recommendations of expert panels were also searched manually. Read More

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http://dx.doi.org/10.18632/oncotarget.17323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581135PMC
August 2017
51 Reads

Vulnerable narcissism is associated with severity of depressive symptoms in dysthymic patients.

Psychiatry Res 2017 11 30;257:265-269. Epub 2017 Jul 30.

Barakaldo Mental Health Center, Mental Health Network of Biscay, Barakaldo, Spain.

Pathological narcissism involves grandiose and vulnerable presentations. Narcissism, and specifically the vulnerable presentation, has been associated to depression, although empirical research studying this relationship is limited. Dysthymia is characterized by a greater treatment resistance and poorer prognosis than other chronic depressive disorders. Read More

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http://dx.doi.org/10.1016/j.psychres.2017.07.061DOI Listing
November 2017
6 Reads

Economic evaluation of stepped-care versus usual care for depression and anxiety in older adults with vision impairment: randomized controlled trial.

BMC Psychiatry 2017 08 1;17(1):280. Epub 2017 Aug 1.

Department of Ophthalmology and the Amsterdam Public Health Research Institute, VU University Medical Centre, De Boelelaan 1117, 1081, Amsterdam, HV, The Netherlands.

Background: A stepped-care program was found effective in preventing depressive and anxiety disorders in older adults with vision impairment. However, before a decision can be made about implementation, the cost-effectiveness of this program should be investigated. Therefore, we aimed to compare the cost-effectiveness of stepped-care versus usual care within low vision rehabilitation. Read More

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http://dx.doi.org/10.1186/s12888-017-1437-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539614PMC
August 2017
19 Reads

Association of restless legs syndrome and mortality in end-stage renal disease: an analysis of the United States Renal Data System (USRDS).

BMC Nephrol 2017 Aug 1;18(1):258. Epub 2017 Aug 1.

Division of Nephrology, Department of Medicine, SUNY Downstate Medical Center, 450 Clarkson Ave, Box 52, Brooklyn, NY, 11203, USA.

Background: Objective of the study is to assess prevalence and survival among end stage renal disease patients with restless legs syndrome (RLS) within a national database (USRDS).

Methods: A case-control, retrospective analysis was performed. Differences in characteristics between the groups, RLS and those with no sleep disorder (NSD), were determined using χ2 tests. Read More

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http://dx.doi.org/10.1186/s12882-017-0660-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540277PMC
August 2017
28 Reads

ARNTL, CLOCK and PER3 polymorphisms - links with chronotype and affective dimensions.

Chronobiol Int 2017 14;34(8):1105-1113. Epub 2017 Jul 14.

b Psychiatric Genetics Unit, Department of Psychiatry , Poznan University of Medical Sciences , Poznan , Poland.

Recently, seven single nucleotide polymorphisms (SNPs) of ARNTL, TIM and PER3 genes were found associated with affective temperaments in bipolar disorder patients. This study aimed to test whether a) the same associations appear in a non-clinical sample; b) the SNPs are related to other affective dimensions; c) the SNPs underpin the associations between chronotype and affective temperaments/dimensions. Three hundred thirty-eight university students completed the Temperament Scale of Memphis, Pisa, Paris and San Diego Auto-questionnaire, the Centre for Epidemiological Studies Depression Scale, the Perceived Stress Scale, the General Health Questionnaire, the Seasonal Pattern Assessment Questionnaire and the Composite Scale of Morningness. Read More

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http://dx.doi.org/10.1080/07420528.2017.1343341DOI Listing
July 2018
14 Reads

Antidepressant effect of taurine in chronic unpredictable mild stress-induced depressive rats.

Sci Rep 2017 07 10;7(1):4989. Epub 2017 Jul 10.

Liaoning Provincial Key Laboratory of Zoonosis, College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang, Liaoning, 110866, P.R. China.

Depression, a psychiatric and dysthymic disorder, severely affects the learning, work and life quality. The main pathogenesis of depression is associated with central nervous system (CNS) dysfunction. Taurine has been demonstrated to exert protective effects on the brain development and can improve learning ability and memory. Read More

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http://dx.doi.org/10.1038/s41598-017-05051-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504064PMC
July 2017
35 Reads

[Influence of depression on the initial diagnosis and the evolution of cognitive impairment].

Rev Neurol 2017 Jul;65(2):63-69

Hospital General Universitario Gregorio Maranon, Madrid, Espana.

Introduction: Depression and cognitive impairment maintain a close and complex relationship, which could be modified by pharmacological treatment.

Aim: To analyze the influence of depression and antidepressive medication on the initial diagnosis and the evolution of cognitive impairment.

Patients And Methods: All the patients derived to a Neurology clinic due to complaints or suspicion of cognitive impairment, during a period of nine years, were studied. Read More

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July 2017
14 Reads

Incremental Benefit-Cost of MOMCare: Collaborative Care for Perinatal Depression Among Economically Disadvantaged Women.

Psychiatr Serv 2017 Nov 3;68(11):1164-1171. Epub 2017 Jul 3.

Dr. Grote and Ms. Lohr are with the School of Social Work, University of Washington, Seattle. Dr. Simon is with Kaiser Permanente Washington Health Research Institute, Seattle. Dr. Russo is with the Department of Psychiatry and Behavioral Sciences, University of Washington Medical Center, Seattle, where the late Dr. Katon was affiliated. Ms. Carson, who is retired, was with Maternity Support Services, Seattle-King County Department of Public Health, Seattle, at the time of this study.

Objective: Effectiveness of collaborative care for perinatal depression has been demonstrated for MOMCare, from early pregnancy up to 15 months postpartum, for Medicaid enrollees in a public health system. MOMCare had a greater impact on reducing depression and improving functioning for women with comorbid posttraumatic stress disorder (PTSD) than for those without PTSD. This study estimated the incremental benefit and cost and the net benefit of MOMCare for women with major depression and PTSD. Read More

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http://dx.doi.org/10.1176/appi.ps.201600411DOI Listing
November 2017
15 Reads

Atypical depression and double depression predict new-onset cardiovascular disease in U.S. adults.

Depress Anxiety 2018 01 22;35(1):10-17. Epub 2017 Jun 22.

Department of Psychology, Indiana University-Purdue University Indianapolis (IUPUI), Indianapolis, IN, USA.

Background: Although depression is a risk factor for cardiovascular disease (CVD), it is unknown whether this risk varies across depressive disorder subtypes. Thus, we investigated atypical major depressive disorder (MDD) and double depression as predictors of new-onset CVD in a nationally representative sample of U.S. Read More

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http://dx.doi.org/10.1002/da.22666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741545PMC
January 2018
36 Reads
4.407 Impact Factor