1,955 results match your criteria Dysthymic Disorder


Frequency of mental disorders among chronic pain patients with or without fibromyalgia in Japan.

Neuropsychopharmacol Rep 2018 Dec 11;38(4):167-174. Epub 2018 Aug 11.

Department of Psychiatry, Osaka University Graduate School of Medicine, Osaka, Japan.

Aim: To explore the characteristics of psychiatric morbidity in chronic pain patients who present with or without fibromyalgia.

Methods: Patients are referred to our chronic pain clinic from primary medical institutions, as we are a secondary medical institution. Although some patients have chronic pain, they have no clear organic disorder such as rheumatoid arthritis to account for the pain. Read More

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December 2018
4 Reads

Citing Hippocrates on depression in epilepsy.

Authors:
Christian Hoppe

Epilepsy Behav 2018 Nov 27;90:31-36. Epub 2018 Nov 27.

Department of Epileptology, University of Bonn Medical Centre, Sigmund-Freud-Strasse 25, FRG-53127 Bonn, Germany. Electronic address:

Objectives: When writing about the bidirectional etiological relationship between depression and epilepsy, neuropsychiatrists often cite Lewis (1934) [Lewis AJ. Melancholia: a historical review. Journal of Mental Science 1934; 80: 1-42] who cited Hippocrates - namely, "melancholics ordinarily become epileptics, and epileptics, melancholics". Read More

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November 2018
1 Read

Incident Chronic Spinal Pain and Depressive Disorders: Data From the National Comorbidity Survey.

J Pain 2018 Nov 22. Epub 2018 Nov 22.

Washington State University, Vancouver, Washington.

This study examined pre-existing depression as a risk factor for the development of chronic spinal pain, and pre-existing chronic spinal pain as a risk factor for the development of depression. Data from the National Comorbidity Survey, a stratified sample of 5,001 participants evaluated in 1990 to 1992 (NCS-1) and again in 2000 to 2001 (NCS-2) were used to address these associations. Cox regression was used to estimate hazard ratios and time-to-incidence after NCS-1. Read More

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November 2018
3 Reads

[Prevalence of bipolar spectrum disorders in migraine patients].

Agri 2018 Oct;30(4):189-198

Department of Psychology, Üsküdar University Faculty of Humanities and Social Sciences, Istanbul, Turkey.

Objectives: Comorbidity of migraine and mood disorders has long been recognized. Most of the studies have focused on the relationship between migraine and major depression with only few studies suggesting a special association between migraine and bipolar spectrum disorders. We aimed to evaluate the prevalence of bipolar disorder in migraine patients in a specialized headache outpatient clinic. Read More

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October 2018
9 Reads

Differences between chronic and nonchronic depression: Systematic review and implications for treatment.

Depress Anxiety 2018 Oct 9. Epub 2018 Oct 9.

Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany.

Background: There is still uncertainty if and to what extent chronic depression (CD) presents with specific features especially in contrast to the nonchronic course of major depressive disorder (non-CD). This systematic review aims to summarize the existing literature regarding sociodemographic factors, psychopathology, and course of disease in patients with CD in comparison to patients with non-CD.

Methods: A structured database search (MEDLINE, PsycINFO, Web of Science, CENTRAL) was performed. Read More

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October 2018
2 Reads

Course and stability of cognitive and metacognitive beliefs in depression.

Depress Anxiety 2018 12 12;35(12):1239-1246. Epub 2018 Sep 12.

Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Maladaptive cognitive beliefs as measured by the Dysfunctional Attitudes Scale (DAS) increase vulnerability to depression. Maladaptive metacognitive beliefs as measured by the Metacognitive Questionnaire-30 (MCQ-30) are also thought to contribute to depression. However, the long-term stability of metacognitive beliefs in depression has not yet been investigated. Read More

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December 2018
1 Read

Persistent depressive disorder has long-term negative impacts on depression, anxiety, and somatic symptoms at 10-year follow-up among patients with major depressive disorder.

J Affect Disord 2019 Jan 18;243:255-261. Epub 2018 Sep 18.

Department of Nursing, Mackay Medical College, Taiwan.

Objective: The study aimed to investigate the impacts of persistent depressive disorder (PDD) and pharmacotherapy on depression, anxiety, and somatic symptoms among patients with major depressive disorder (MDD) over a ten-year period.

Methods: 290 outpatients with MDD were enrolled, including 117 with PDD, at baseline. Subjects were followed-up at six-month, two-year, and 10-year points. Read More

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January 2019
1 Read

Social cognitive abilities predict psychosocial dysfunction in major depressive disorder.

Depress Anxiety 2018 Sep 13. Epub 2018 Sep 13.

Department of Psychiatry, Melbourne Medical School, University of Melbourne, Melbourne, VIC, Australia.

Background: Major depressive disorder (MDD) is associated with social cognitive deficits (e.g., poor affect recognition and impaired theory of mind). Read More

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September 2018
3 Reads

Moderating effect of comorbid anxiety disorders on treatment outcome in a randomized controlled psychotherapy trial in early-onset persistently depressed outpatients.

Depress Anxiety 2018 10 10;35(10):1001-1008. Epub 2018 Sep 10.

Department of Psychiatry and Psychotherapy, Lübeck University, Lübeck, Germany.

Background: Persistent depressive disorder (PDD) is associated with high rates of comorbid psychiatric disorders, mostly anxiety disorders (ADs). Comorbid AD was found to be associated with poorer treatment outcome in PDD patients. The effect of comorbid AD on disorder-specific treatment for PDD (Cognitive Behavioral Analysis System of Psychotherapy [CBASP]) has not been studied yet. Read More

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October 2018
2 Reads

Depression Plays a Moderating Role in the Cognitive Decline Associated With Changes of Brain White Matter Hyperintensities.

J Clin Psychiatry 2018 Sep 4;79(5). Epub 2018 Sep 4.

Department of Neuropsychiatry, Seoul National University Bundang Hospital, 300 Gumidong, Bundanggu, Seongnamsi, Gyeonggi-do, Korea 463-707.

Objective: In the elderly, depression and white matter hyperintensities (WMH) are common and associated with cognitive impairment. This study investigated the possible interactions between depression and WMH in their influences on cognition of the elderly.

Methods: Using multiple neuropsychological tests, we evaluated the cognitive function of 122 community-dwelling elders with depression at baseline between November 2008 and February 2009. Read More

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September 2018
73 Reads

Protective Role of L-3--Butylphthalide in Cognitive Function and Dysthymic Disorders in Mouse With Chronic Epilepsy.

Front Pharmacol 2018 11;9:734. Epub 2018 Jul 11.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, China.

Epilepsy is a common neurological disease with recurrent seizures and neurobehavioral comorbidities, including cognitive impairment and psychiatric disorders. Recent studies suggest that L-3--butylphthalide (NBP), an extract from the seeds of Linn. (Chinese celery), ameliorates cognitive dysfunction in ischemia and/or Alzheimer's disease animal models. Read More

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July 2018
1 Read

Clinical and radiological characteristics of early versus late mild cognitive impairment in patients with comorbid depressive disorder.

Int J Geriatr Psychiatry 2018 Dec 23;33(12):1604-1612. Epub 2018 Jul 23.

Columbia University, New York, NY, USA.

Objective: The classification of mild cognitive impairment (MCI) continues to be debated though it has recently been subtyped into late (LMCI) versus early (EMCI) stages. Older adults presenting with both a depressive disorder (DEP) and cognitive impairment (CI) represent a unique, understudied population. Our aim was to examine baseline characteristics of DEP-CI patients in the DOTCODE trial, a randomized controlled trial of open antidepressant treatment for 16 weeks followed by add-on donepezil or placebo for 62 weeks. Read More

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December 2018
2 Reads

CBT and positive psychology interventions for clinical depression promote healthy attentional biases: An eye-tracking study.

Depress Anxiety 2018 10 20;35(10):966-973. Epub 2018 Jul 20.

Department of Psychology, Faculty of Health Sciences, Francisco de Vitoria University, Madrid, Spain.

Background: Although there is a growing interest in the role of attentional biases in depression, there are no studies assessing changes in these biases after psychotherapeutic interventions.

Methods: We used a validated eye-tracking procedure to assess pre-post therapy changes in attentional biases toward emotional information (i.e. Read More

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October 2018
2 Reads

Heterogeneity in Male Adolescents With Illegal Sexual Behavior: A Latent Profile Approach to Classification.

Sex Abuse 2018 Jul 1:1079063218784554. Epub 2018 Jul 1.

1 Auburn University, AL, USA.

Current research has established that male adolescents with illegal sexual behavior (AISB) are a heterogeneous population. We aimed to explore this within-group heterogeneity to derive clinically relevant groups of AISB using the Millon Adolescent Clinical Inventory (MACI). We then compared these groups on selected covariates (age at intake, minority status, and child maltreatment history) and distal outcomes (general, nonviolent, violent, drug, and sexual recidivism 5 years after release) to identify any differences. Read More

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July 2018
3 Reads

Trajectories after first-episode psychosis: Complement to ambiguous outcomes of long-term antipsychotic treatment by exploring a few hidden cases.

Early Interv Psychiatry 2018 Jun 21. Epub 2018 Jun 21.

Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan.

Aim: Patient's long-term phenomenology after first-episode psychosis could be blurred due to early intervention. The contradictory messages regarding necessity of long-term antipsychotic treatment derived from different methodologies warrants careful reappraisal.

Methods: We approached a group of patients lost to follow-up in a previous study. Read More

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June 2018
2 Reads

Anaerobic muscle strengthening physical activity and depression severity among USA adults.

Prev Med Rep 2018 Jun 14;10:299-303. Epub 2018 Mar 14.

Ohio State University, United States.

We investigated the association between depression and anaerobic physical activity (while controlling aerobic physical activity), using a nationally representative sample of USA adults ( = 7354) who participated in the cross sectional National Health and Nutrition Examination Survey (NHANES, 1999-2006). We defined depression using the validated "Patient Health Questionnaire" (PHQ) scale of 0-27 as PHQ  10. Severity of depression was classified by clinically established PHQ levels: mild (5-9), dysthymic (10-14), moderate (15-19), and major depression (20). Read More

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June 2018
1 Read

The ICD-11 developmental field study of reliability of diagnoses of high-burden mental disorders: results among adult patients in mental health settings of 13 countries.

World Psychiatry 2018 Jun;17(2):174-186

Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA.

Reliable, clinically useful, and globally applicable diagnostic classification of mental disorders is an essential foundation for global mental health. The World Health Organization (WHO) is nearing completion of the 11th revision of the International Classification of Diseases and Related Health Problems (ICD-11). The present study assessed inter-diagnostician reliability of mental disorders accounting for the greatest proportion of global disease burden and the highest levels of service utilization - schizophrenia and other primary psychotic disorders, mood disorders, anxiety and fear-related disorders, and disorders specifically associated with stress - among adult patients presenting for treatment at 28 participating centers in 13 countries. Read More

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June 2018
12 Reads
1 Citation
14.220 Impact Factor

Prevalence of anxiety and depressive disorders among youth with intellectual disabilities: A systematic review and meta-analysis.

J Affect Disord 2018 08 6;236:230-242. Epub 2018 Apr 6.

Department of Psychoeducation and Psychology, Université du Québec en Outaouais (UQO), Saint-Jérôme, Canada; School of Public Health, Department of Social and Preventive Medicine, Université de Montréal, Montréal, Canada; Research Center, Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Nord-de-l'Île-de-Montréal, Montréal, Canada.

Background: The purpose of this meta-analytic study was to determine the pooled prevalence estimates of anxiety and depressive disorders among children and adolescents with intellectual disabilities (ID) and to assess the extent to which these pooled prevalence rates differed according to studies' characteristics.

Method: A systematic literature search was performed in nine databases and 21 studies, published between 1975 and 2015, met the inclusion criteria.

Results: The resulting pooled prevalence estimates of combined subtypes of anxiety and depressive disorders were respectively (a) 5. Read More

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August 2018
4 Reads

Characterizing anxiety subtypes and the relationship to behavioral phenotyping in major depression: Results from the EMBARC study.

J Psychiatr Res 2018 Jul 6;102:207-215. Epub 2018 Apr 6.

The University of Texas Southwestern Medical Center, Department of Psychiatry, Center for Depression Research and Clinical Care, Department of Psychiatry, Dallas, TX, USA. Electronic address:

The current study aimed to characterize the multifaceted nature of anxiety in patients with major depression by evaluating distinct anxiety factors. We then related these derived anxiety factors to performance on a Flanker Task of cognitive control, in order to further validate these factors. Data were collected from 195 patients with nonpsychotic chronic or recurrent major depression or dysthymic disorder. Read More

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July 2018
11 Reads

Antidepressants for the treatment of depression in people with cancer.

Cochrane Database Syst Rev 2018 04 23;4:CD011006. Epub 2018 Apr 23.

​Department of Neuroscience, Biomedicine and Movement Sciences, Section of Psychiatry, University of Verona, Policlinico "GB Rossi", Piazzale L.A. Scuro, 10, Verona, Italy, 37134.

Background: Major depression and other depressive conditions are common in people with cancer. These conditions are not easily detectable in clinical practice, due to the overlap between medical and psychiatric symptoms, as described by diagnostic manuals such as the Diagnostic and Statistical Manual of Mental Disorders (DSM) and International Classification of Diseases (ICD). Moreover, it is particularly challenging to distinguish between pathological and normal reactions to such a severe illness. Read More

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April 2018
4 Reads

Emerging psychiatric disorders in Kleine-Levin syndrome.

J Sleep Res 2018 Oct 14;27(5):e12690. Epub 2018 Apr 14.

National Reference Centre for Narcolepsy, Hypersomnia and Kleine-Levin Syndrome, Pitie-Salpetriere University Hospital, AP-HP, Paris, France.

In Kleine-Levin syndrome (KLS), episodes of hypersomnia and cognitive, psychiatric and behavioural disturbances alternate with asymptomatic periods in adolescents. We evaluated whether psychiatric disorders would emerge during asymptomatic periods in a naturalistic, uncontrolled clinical cohort. Patients with primary KLS underwent psychiatric interviews at diagnosis and every year for 1-10 years, leading to diagnosis of former and present comorbid psychiatric disorders. Read More

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October 2018
6 Reads

The association between lifetime cannabis use and dysthymia across six birth decades.

J Affect Disord 2018 07 16;234:327-334. Epub 2018 Mar 16.

Lev Hasharon Medical Center, Israel; Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: Though high rates of co-occurring cannabis use and depression are well-documented, data regarding the association between cannabis use and dysthymia is scarce. The aim of this cross-sectional study was to explore clinical correlations of cannabis use among individuals with dysthymia, as well as the changes in the association between cannabis use and dysthymia across six decades of birth cohorts.

Methods: Data were drawn from the National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III; 2012-2013; N = 36,309). Read More

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July 2018
5 Reads

Obsessive-compulsive disorder and the risk of subsequent mental disorders: A community study of adolescents and young adults.

Depress Anxiety 2018 04 28;35(4):339-345. Epub 2018 Feb 28.

Division of Clinical Psychology and Epidemiology, Department of Psychology, University of Basel, Basel, Switzerland.

Background: Comorbidity of obsessive-compulsive disorder (OCD) with other mental disorders has been demonstrated repeatedly. Few longitudinal studies, however, have evaluated the temporal association of prior OCD and subsequent mental disorders across the age period of highest risk for first onset of mental disorders. We examined associations between prior OCD and a broad range of subsequent mental disorders and simulated proportions of new onsets of mental disorders that could potentially be attributed to prior OCD, assuming a causal relationship. Read More

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April 2018
7 Reads

Antidepressant effects of dammarane sapogenins in chronic unpredictable mild stress-induced depressive mice.

Phytother Res 2018 Jun 22;32(6):1023-1029. Epub 2018 Feb 22.

Research Center for Pharmacology and Toxicology, Institute of Medicinal Plant Development (IMPLAD), Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100006, China.

Depression is a common, dysthymic, and psychiatric disorder, resulting in enormous social and economic burden. Dammarane sapogenins (DS), an active fraction from oriental ginseng, has shown antidepressant-like effects in chronic restraint rats and sleep interruption-induced mice, and the present study aimed to further confirm the antidepressant effects of DS in a model of chronic unpredictable mild stress (CUMS) and to explore the underlying mechanism. Oral administration of DS (20, 40, and 80 mg/kg) markedly improved depressant-like behaviors, increasing the sucrose intake in the sucrose preference test and reducing the latency in the novelty-suppressed feeding test, and decreasing the immobility time in both the tail suspension and forced swimming tests, compared with the CUMS mice. Read More

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June 2018
7 Reads

Childhood trajectories of peer victimization and prediction of mental health outcomes in midadolescence: a longitudinal population-based study.

CMAJ 2018 01;190(2):E37-E43

McGill Group for Suicide Studies (Geoffroy, Renaud, Perret, Turecki) and Manulife Centre for Breakthroughs in Teen Depression and Suicide Prevention (Renaud), Douglas Mental Health University Institute; McGill University (Geoffroy, Renaud, Perret, Turecki), Montréal, Que.; Research Unit on Children's Psychosocial Maladjustment (Geoffroy, Boivin, Turecki, Vitaro, Brendgen, Tremblay, Côté), Montréal and Québec, Que.; Université Laval (Boivin), Québec, Que.; Institute of Genetic, Neurobiological, and Social Foundations of Child Development at Tomsk State University (Boivin), Tomsk, Russian Federation; Institute of Psychiatry, Psychology and Neuroscience (Arseneault), King's College London, London, UK; Centre de recherche INSERM U1219 (Michel, Salla, Côté), Université de Bordeaux, Bordeaux, France; Université de Montréal (Vitaro, Tremblay, Côté); CHU Sainte-Justine Research Center (Vitaro, Brendgen); Université du Québec à Montréal (Brendgen), Montréal, Que.; University College Dublin (Tremblay), Dublin, Ireland.

Background: Exposure to peer victimization is relatively common. However, little is known about its developmental course and its effect on impairment associated with mental illnesses. We aimed to identify groups of children following differential trajectories of peer victimization from ages 6 to 13 years and to examine predictive associations of these trajectories with mental health in adolescence. Read More

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January 2018
39 Reads

Mood disorders in familial epilepsy: A test of shared etiology.

Epilepsia 2018 02 10;59(2):431-439. Epub 2018 Jan 10.

Department of Genetics, Human Genetics Institute of New Jersey, Rutgers, State University of New Jersey, Piscataway, NJ, USA.

Objective: Mood disorders are the most common comorbid conditions in epilepsy, but the cause remains unclear. One possible explanation is a shared genetic susceptibility to epilepsy and mood disorders. We tested this hypothesis by evaluating lifetime prevalence of mood disorders in relatives with and without epilepsy in families containing multiple individuals with epilepsy, and comparing the findings with rates from a general population sample. Read More

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February 2018
2 Reads

Clinical and Genetic Predictors of Delayed Remission After Multiple Levels of Antidepressant Treatment: Toward Early Identification of Depressed Individuals for Advanced Care Options.

J Clin Psychiatry 2017 Nov/Dec;78(9):e1291-e1298

Department of Psychiatry, The University of Alabama, Birmingham, Alabama, USA.

Objective: To identify clinical and genetic characteristics that can be used to recognize depressed patients who are likely to respond quickly versus those who will have a more delayed response following multiple treatment trials.

Methods: The data used were obtained from the National Institute of Mental Health-sponsored Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study, which was conducted between July 2001 and September 2006. Of the 4,041 treatment-naive participants in the original study, 1,953 with DNA samples were included. Read More

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January 2017
11 Reads

Comorbidity of narcolepsy and depressive disorders: a nationwide population-based study in Taiwan.

Sleep Med 2017 Nov 5;39:95-100. Epub 2017 Sep 5.

Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Department of Chinese Medicine, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan, Taiwan. Electronic address:

Objective: Narcolepsy is a chronic sleep disorder that is likely to have neuropsychiatric comorbidities. Depression is a serious mood disorder that affects individuals' daily activities and functions. The current study aimed to investigate the relationship between narcolepsy and depressive disorders. Read More

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November 2017
6 Reads

Pattern of Changes during Treatment: A Comparison between a Positive Psychology Intervention and a Cognitive Behavioral Treatment for Clinical Depression.

Span J Psychol 2017 Oct 26;20:E52. Epub 2017 Oct 26.

Universidad Complutense (Spain).

Research on psychotherapy has traditionally focused on analyzing changes between the beginning and the end of a treatment. Few studies have addressed the pattern of therapeutic change during treatment. The aim of this study was to examine the pattern of changes in clinical and well-being variables during a cognitive behavioral therapy (CBT) program compared with an integrative positive psychology interventions program for clinical depression IPPI-D. Read More

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October 2017
6 Reads

Clinical characteristics of patients with diagnostic uncertainty of major depressive disorder.

Asian J Psychiatr 2017 Dec 16;30:159-162. Epub 2017 Oct 16.

Department of Psychiatry, National Defense Medical College, Saitama, Japan. Electronic address:

Background: Physicians do not always confidently diagnose psychiatric disorders. The present study was conducted to identify the clinical characteristics of patients in whom a definitive diagnosis of major depressive disorder (MDD) could not be established.

Methods: The participants were 199 consecutive outpatients with MDD, who were comprehensively diagnosed using the Mini International Neuropsychiatric Interview (MINI). Read More

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December 2017
9 Reads

Multimorbidity is associated with increased rates of depression in patients hospitalized with diabetes mellitus in the United States.

J Diabetes Complications 2017 Nov 4;31(11):1571-1579. Epub 2017 Aug 4.

Department of Family and Community Medicine, Baylor College of Medicine, 3701 Kirby Dr., Suite 600 (MS: BCM700), Houston, TX 77098, USA.

Aims: Information on the burden and risk factors for diabetes-depression comorbidity in the US is sparse. We used data from the largest all-payer, nationally-representative inpatient database in the US to estimate the prevalence, temporal trends, and risk factors for comorbid depression among adult diabetic inpatients.

Methods: We conducted a retrospective analysis using the 2002-2014 Nationwide Inpatient Sample databases. Read More

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November 2017
12 Reads
1.920 Impact Factor

The prevalence of depression in rheumatoid arthritis in China: A systematic review.

Oncotarget 2017 Aug 21;8(32):53623-53630. Epub 2017 Apr 21.

Children's Research Institute, Children's National Medical Center, Washington, DC, USA.

This systematic review is to explore the prevalence of depression in patients with rheumatoid arthritis (RA) in China. Articles of prevalence rates for depression in adult RA patients published before October 2015 were identified from PubMed, Embase, The Cochrane Library, CNKI, CBM, VIP, and Wanfang database and other internet databases. Relevant journals and the recommendations of expert panels were also searched manually. Read More

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August 2017
27 Reads

Association between physiological oscillations in self-esteem, narcissism and internet addiction: A cross-sectional study.

Psychiatry Res 2017 12 19;258:239-243. Epub 2017 Aug 19.

University of East Sarajevo, Faculty of Medicine, Studentska 5, 73300 Foca, Bosnia and Herzegovina.

Internet addiction is a novel and relatively uninvestigated form of dependence that is fairly common in adolescent population. Previous research has indicated that it may be associated with other mental health problems, such as dysthymic mood and narcissistic behavior. In our study, we tested the existence and strength of relationship between Internet addiction, self-esteem and narcissism in a student population. Read More

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December 2017
21 Reads
2.470 Impact Factor

Vulnerable narcissism is associated with severity of depressive symptoms in dysthymic patients.

Psychiatry Res 2017 11 30;257:265-269. Epub 2017 Jul 30.

Barakaldo Mental Health Center, Mental Health Network of Biscay, Barakaldo, Spain.

Pathological narcissism involves grandiose and vulnerable presentations. Narcissism, and specifically the vulnerable presentation, has been associated to depression, although empirical research studying this relationship is limited. Dysthymia is characterized by a greater treatment resistance and poorer prognosis than other chronic depressive disorders. Read More

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November 2017
2 Reads

Economic evaluation of stepped-care versus usual care for depression and anxiety in older adults with vision impairment: randomized controlled trial.

BMC Psychiatry 2017 08 1;17(1):280. Epub 2017 Aug 1.

Department of Ophthalmology and the Amsterdam Public Health Research Institute, VU University Medical Centre, De Boelelaan 1117, 1081, Amsterdam, HV, The Netherlands.

Background: A stepped-care program was found effective in preventing depressive and anxiety disorders in older adults with vision impairment. However, before a decision can be made about implementation, the cost-effectiveness of this program should be investigated. Therefore, we aimed to compare the cost-effectiveness of stepped-care versus usual care within low vision rehabilitation. Read More

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August 2017
9 Reads

Association of restless legs syndrome and mortality in end-stage renal disease: an analysis of the United States Renal Data System (USRDS).

BMC Nephrol 2017 Aug 1;18(1):258. Epub 2017 Aug 1.

Division of Nephrology, Department of Medicine, SUNY Downstate Medical Center, 450 Clarkson Ave, Box 52, Brooklyn, NY, 11203, USA.

Background: Objective of the study is to assess prevalence and survival among end stage renal disease patients with restless legs syndrome (RLS) within a national database (USRDS).

Methods: A case-control, retrospective analysis was performed. Differences in characteristics between the groups, RLS and those with no sleep disorder (NSD), were determined using χ2 tests. Read More

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August 2017
12 Reads

[Peculiarities of clinical psychopathological phenomenology of chronic neuropathies].

Wiad Lek 2017;70(3 pt 2):592-595

Vinnitsa National Pirogov Memorial Medical University, Vinnitsa, Ukraine.

Introduction: The study of psycho-emotional reactions associated with chronic neuropathies, is an important factor of the integrated solution to the problem of treatment and prevention of disorders of the peripheral nervous system. The aim of the research is to study clinical psychopathological phenomenology and personality characteristics of patients suffering from chronic neuropathies.

Material And Methods: We examined 115 patients with chronic neuropathies in comparison with 60 healthy persons using a clinical conversation method, shortened multivariable personality questionnaire, The Zung Self-Rating Depression Scale, Spilberger's scale of trait and state anxiety and Symptom Check List-90-Revised questionnaire. Read More

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October 2018
1 Read

ARNTL, CLOCK and PER3 polymorphisms - links with chronotype and affective dimensions.

Chronobiol Int 2017 14;34(8):1105-1113. Epub 2017 Jul 14.

b Psychiatric Genetics Unit, Department of Psychiatry , Poznan University of Medical Sciences , Poznan , Poland.

Recently, seven single nucleotide polymorphisms (SNPs) of ARNTL, TIM and PER3 genes were found associated with affective temperaments in bipolar disorder patients. This study aimed to test whether a) the same associations appear in a non-clinical sample; b) the SNPs are related to other affective dimensions; c) the SNPs underpin the associations between chronotype and affective temperaments/dimensions. Three hundred thirty-eight university students completed the Temperament Scale of Memphis, Pisa, Paris and San Diego Auto-questionnaire, the Centre for Epidemiological Studies Depression Scale, the Perceived Stress Scale, the General Health Questionnaire, the Seasonal Pattern Assessment Questionnaire and the Composite Scale of Morningness. Read More

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July 2018
4 Reads

Antidepressant effect of taurine in chronic unpredictable mild stress-induced depressive rats.

Sci Rep 2017 Jul 10;7(1):4989. Epub 2017 Jul 10.

Liaoning Provincial Key Laboratory of Zoonosis, College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang, Liaoning, 110866, P.R. China.

Depression, a psychiatric and dysthymic disorder, severely affects the learning, work and life quality. The main pathogenesis of depression is associated with central nervous system (CNS) dysfunction. Taurine has been demonstrated to exert protective effects on the brain development and can improve learning ability and memory. Read More

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July 2017
18 Reads

[Influence of depression on the initial diagnosis and the evolution of cognitive impairment].

Rev Neurol 2017 Jul;65(2):63-69

Hospital General Universitario Gregorio Maranon, Madrid, Espana.

Introduction: Depression and cognitive impairment maintain a close and complex relationship, which could be modified by pharmacological treatment.

Aim: To analyze the influence of depression and antidepressive medication on the initial diagnosis and the evolution of cognitive impairment.

Patients And Methods: All the patients derived to a Neurology clinic due to complaints or suspicion of cognitive impairment, during a period of nine years, were studied. Read More

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July 2017
11 Reads

Incremental Benefit-Cost of MOMCare: Collaborative Care for Perinatal Depression Among Economically Disadvantaged Women.

Psychiatr Serv 2017 Nov 3;68(11):1164-1171. Epub 2017 Jul 3.

Dr. Grote and Ms. Lohr are with the School of Social Work, University of Washington, Seattle. Dr. Simon is with Kaiser Permanente Washington Health Research Institute, Seattle. Dr. Russo is with the Department of Psychiatry and Behavioral Sciences, University of Washington Medical Center, Seattle, where the late Dr. Katon was affiliated. Ms. Carson, who is retired, was with Maternity Support Services, Seattle-King County Department of Public Health, Seattle, at the time of this study.

Objective: Effectiveness of collaborative care for perinatal depression has been demonstrated for MOMCare, from early pregnancy up to 15 months postpartum, for Medicaid enrollees in a public health system. MOMCare had a greater impact on reducing depression and improving functioning for women with comorbid posttraumatic stress disorder (PTSD) than for those without PTSD. This study estimated the incremental benefit and cost and the net benefit of MOMCare for women with major depression and PTSD. Read More

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November 2017
12 Reads

Atypical depression and double depression predict new-onset cardiovascular disease in U.S. adults.

Depress Anxiety 2018 01 22;35(1):10-17. Epub 2017 Jun 22.

Department of Psychology, Indiana University-Purdue University Indianapolis (IUPUI), Indianapolis, IN, USA.

Background: Although depression is a risk factor for cardiovascular disease (CVD), it is unknown whether this risk varies across depressive disorder subtypes. Thus, we investigated atypical major depressive disorder (MDD) and double depression as predictors of new-onset CVD in a nationally representative sample of U.S. Read More

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January 2018
17 Reads

White matter microstructure in boys with persistent depressive disorder.

J Affect Disord 2017 10 13;221:11-16. Epub 2017 Jun 13.

Developmental Imaging, Murdoch Childrens Research Institute, Parkville, Australia.

Background: Persistent depressive symptoms in children and adolescents are considered a risk factor for the development of major depressive disorder (MDD) later in life. Previous research has shown alterations in white matter microstructure in pediatric MDD but discrepancies exist as to the specific tracts affected. The current study aimed to improve upon previous methodology and address the question whether previous findings of lower fractional anisotropy (FA) replicate in a sample of children with persistent depressive disorder characterized by mild but more chronic symptoms of depression. Read More

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October 2017
7 Reads

[Conflict dynamics in chronic depression - Results of the conflict and structure axis using the OPD in the LAC Study].

Z Psychosom Med Psychother 2017 Jun;63(2):151-162

Sigmund-Freud-Institut Myliusstr. 20 60323 Frankfurt amMain Deutschland Sigmund-Freud-Institut.

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June 2017
21 Reads

Differences in clinical and cognitive variables in seasonal affective disorder compared to depressive-related disorders: Evidence from a population-based study in Finland.

Eur Psychiatry 2017 07 28;44:9-16. Epub 2017 Mar 28.

Department of Health, National Institute for Health and Welfare (THL), P.O. Box 30, Mannerheimintie 168b, FI-00271, Helsinki, Finland.

Background: Seasonal affective disorder (SAD) is a type of depression with seasonal pattern. Although it involves some idiosyncratic symptoms, it can overlap with other depressive disorders such as major depressive disorder (MDD) or dysthymia. We aimed to characterize the differences in specific cognitive and clinical symptoms between SAD and depressive-related disorders. Read More

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July 2017
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