64,281 results match your criteria Dysphagia


The predictive dysphagia score (PreDyScore) in the short- and medium-term post-stroke: a putative tool in PEG indication.

Neurol Sci 2019 Apr 19. Epub 2019 Apr 19.

Unità Operativa Dietetica e Nutrizione Clinica, IRCCS per l'Oncologia e la Neurologia, Ospedale Policlinico San Martino, Genoa, Italy.

Purpose: We performed an evaluation of dysphagia in an unselected series of strokes to identify factors causing persisting dysphagia at 1 month after onset and to formulate a predictive score.

Methods: We evaluated the association between dysphagia and clinical aspects (univariate analysis) at the 7th and 30th days after admission. We performed a multivariate logistic regression at the 30th day on the factors that were significant. Read More

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http://dx.doi.org/10.1007/s10072-019-03896-2DOI Listing

Functional and oncological outcomes after retropharyngeal node dissection for papillary thyroid carcinoma.

Eur Arch Otorhinolaryngol 2019 Apr 19. Epub 2019 Apr 19.

Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, 7-5-1, Kusunoki-cho, Chuo-Ku, Kobe, Hyogo, 650-0017, Japan.

Background: Papillary thyroid carcinoma frequently metastasizes to central and lateral neck lymph nodes, but metastasis to retropharyngeal lymph nodes (RPLN) is rare.

Patients And Methods: We retrospectively reviewed 16 patients with RPLN metastasis of PTC who underwent therapeutic dissection of RPLN metastases.

Results: Among 16 patients, 7 patients underwent RPLN dissection with initial surgery and remaining 9 patients as salvage surgery. Read More

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http://dx.doi.org/10.1007/s00405-019-05420-wDOI Listing

Clinical guide for the diagnosis and follow-up of myotonic dystrophy type 1, MD1 or Steinert's disease.

Neurologia 2019 Apr 16. Epub 2019 Apr 16.

Servicio de Neurología, Hospital Universitario 12 de Octubre, Madrid, España.

Background And Objectives: Steinert's disease or myotonic dystrophy type 1 (MD1), (OMIM 160900), is the most prevalent myopathy in adults. It is a multisystemic disorder with dysfunction of virtually all organs and tissues and a great phenotypical variability, which implies that it has to be addressed by different specialities with experience in the disease. The knowledge of the disease and its management has changed dramatically in recent years. Read More

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http://dx.doi.org/10.1016/j.nrl.2019.01.001DOI Listing

Neurological conditions and acute dysphagia.

Authors:
Katie Atkinson

Br J Nurs 2019 Apr;28(8):490-492

Highly Specialised Speech and Language Therapist, National Hospital for Neurology and Neurosurgery, London.

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http://dx.doi.org/10.12968/bjon.2019.28.8.490DOI Listing

Lingual and Maxillary Labial Frenuloplasty with Myofunctional Therapy as a Treatment for Mouth Breathing and Snoring.

Case Rep Otolaryngol 2019 10;2019:3408053. Epub 2019 Mar 10.

The Breathe Institute, Los Angeles, CA, USA.

Chronic mouth breathing may adversely affect craniofacial development in children and may result in anatomical changes that directly impact the stability and collapsibility of the upper airway during sleep. Mouth breathing is a multifactorial problem that can be attributed to structural, functional, and neurological etiologies, which are not all mutually exclusive. While therapeutic interventions (myofunctional, speech and swallowing, occupational, and craniosacral therapy) may address the functional and behavioral factors that contribute to mouth breathing, progress may sometimes be limited by restrictive lingual and labial frenum that interfere with tongue and lip mobility. Read More

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http://dx.doi.org/10.1155/2019/3408053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437727PMC

The Swallowing Clinical Assessment Score in Parkinson's Disease (SCAS-PD) Is a Valid and Low-Cost Tool for Evaluation of Dysphagia: A Gold-Standard Comparison Study.

J Aging Res 2019 13;2019:7984635. Epub 2019 Mar 13.

Graduate Program in Biomedical Gerontology, School of Medicine, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil.

Background: Dysphagia is a predictor of mortality in Parkinson's disease (PD). Developing alternative methods to videofluoroscopy swallowing study (VFSS) for the evaluation of dysphagia is a public health necessity. The is an alternative and low-cost tool for diagnosis of dysphagia, but had not been properly validated in comparison to the gold-standard method. Read More

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http://dx.doi.org/10.1155/2019/7984635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436359PMC
March 2019
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Clinical presentation and outcome after anterior cervical discectomy and fusion for degenerative cervical disc disease.

J Craniovertebr Junction Spine 2019 Jan-Mar;10(1):28-32

Department of Neurosurgery, Narayana Medical College Hospital, Nellore, Andhra Pradesh, India.

Background: Anterior cervical discectomy and fusion (ACDF) is a well-described surgical approach for symptomatic degenerative cervical disc disease which does not respond to conservative management. In the present study, we assessed clinical presentation and outcomes of ACDF.

Materials And Methods: The present study was conducted from October 1, 2015, to October 31, 2017, in the Department of Neurosurgery, Narayana Medical College and Hospital, Nellore, Andhra Pradesh, among 100 consecutive adult patients who underwent single- or two-level ACDF for degenerative cervical disc disease. Read More

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http://dx.doi.org/10.4103/jcvjs.JCVJS_87_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469327PMC

Swallowing Safety and Efficiency after Open Partial Horizontal Laryngectomy: A Videofluoroscopic Study.

Cancers (Basel) 2019 Apr 17;11(4). Epub 2019 Apr 17.

Head and Neck Oncology Service, Candiolo Cancer Institute-FPO IRCCS, Strada Provinciale 142 km 95, 10060 Candiolo (TO), Italy.

Dysphagia is common after an open partial horizontal laryngectomy (OPHL). The mechanisms causing lower airways' invasion and pharyngeal residue are unclear. The study aims to examine physio-pathological mechanisms affecting swallowing safety and efficiency after OPHL. Read More

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http://dx.doi.org/10.3390/cancers11040549DOI Listing

The Mealtime Assessment Scale (MAS): Part 1 - Development of a Scale for Meal Assessment.

Folia Phoniatr Logop 2019 Apr 18:1-13. Epub 2019 Apr 18.

Department of Biomedical and Clinical Sciences "L. Sacco," Università degli Studi di Milano, Milan, Italy.

Aims: Safety and efficacy of swallowing in instrumental assessment may not overlap safety and efficacy of swallowing during meal, as personal and environmental factors can influence the performance. This study aims to develop a scale to assess the safety and efficacy of swallowing during meal.

Methods: A working group discussed the latent construct, target population, and purposes of the scale. Read More

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https://www.karger.com/Article/FullText/494135
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http://dx.doi.org/10.1159/000494135DOI Listing
April 2019
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Clinical Significance of the Esophageal Outflow Resistance Imposed by a Nissen Fundoplication.

J Am Coll Surg 2019 Apr 15. Epub 2019 Apr 15.

Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA. Electronic address:

Background: Attention has been focused on the amplitude of esophageal body contraction to avoid persistent dysphagia after a Nissen fundoplication. The current recommended level is a contraction amplitude in the distal third of esophagus above the 5th percentile. We hypothesized that a more physiologic approach is to measure outflow resistance imposed by a fundoplication, which needs be overcome by the esophageal contraction amplitude. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10727515193027
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http://dx.doi.org/10.1016/j.jamcollsurg.2019.03.024DOI Listing
April 2019
1 Read

Correlation Between Clinical Course and Biochemical Analysis in Odontogenic Space Infections.

J Maxillofac Oral Surg 2019 Jun 22;18(2):203-209. Epub 2018 Jun 22.

Department of Oral and Maxillofacial Surgery, Sri Guru Ram Das Institute of Dental Sciences and Research, Mall Mandi, Amritsar, Punjab 143006 India.

Objective: To correlate the clinical course and biochemical analysis in odontogenic space infections.

Methods: A randomized prospective study was undertaken in 50 patients presenting with infections of odontogenic origin. The data were subjected to statistical analysis to co-relate the values of CRP, WBC count and ESR with the clinical course of odontogenic infections. Read More

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http://link.springer.com/10.1007/s12663-018-1132-1
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http://dx.doi.org/10.1007/s12663-018-1132-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441441PMC
June 2019
1 Read

Management of Dysphagia in Patients with Parkinson's Disease and Related Disorders.

Intern Med 2019 Apr 17. Epub 2019 Apr 17.

Department of Neurology, Kochi Medical School, Kochi University, Japan.

Various methods of rehabilitation for dysphagia have been suggested through the experience of treating stroke patients. Although most of these patients recover their swallowing function in a short period, dysphagia in Parkinson's disease (PD) and Parkinson-related disorder (PRD) degenerates with disease progression. Muscle rigidity and bradykinesia are recognized as causes of swallowing dysfunction, and it is difficult to easily apply the strategies for stroke to the rehabilitation of dysphagia in PD patients. Read More

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http://dx.doi.org/10.2169/internalmedicine.2373-18DOI Listing
April 2019
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Endoscopic Ultrasound-guided Drainage of a Mediastinal Abscess Caused by an Ingested Fish Bone.

Intern Med 2019 Apr 17. Epub 2019 Apr 17.

Division of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine, Japan.

Cases of foreign body ingestion are encountered relatively often in clinical settings; however, serious complications are rare. In such cases, mediastinal abscess due to esophageal perforation can become a life-threatening complication. Although highly invasive, surgery is often used as the first-line treatment. Read More

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http://dx.doi.org/10.2169/internalmedicine.1992-18DOI Listing
April 2019
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Myopathy in a 61-year-old Hispanic man.

BMJ Case Rep 2019 Apr 16;12(4). Epub 2019 Apr 16.

Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

A 61-year-old Hispanic man presented to a county hospital for subacute progressive weakness, heliotrope rash and dysphagia. There was initial suspicion for dermatomyositis (DM) given the history; however, the physical exam was not consistent. An MRI followed by a muscle biopsy revealed necrotising autoimmune myositis and anti-3-hydroxy-3-methylglutary-coenzyme A-reductase antibody titers returned positive; the patient was diagnosed with necrotising autoimmune myositis. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22889
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http://dx.doi.org/10.1136/bcr-2018-228892DOI Listing
April 2019
2 Reads

Caustic Agents Ingestion in Children: A 51-Year Retrospective Cohort Study.

Ear Nose Throat J 2019 Apr 17:145561319843109. Epub 2019 Apr 17.

3 Clinic of Pediatric Otolaryngology, Phoniatrics and Audiology, Medical University of Lublin, Lublin, Poland.

Objectives: Children experience serious gastrointestinal tract injuries due to consumption of caustic agents more often than adults. The aim of the study was to analyze diagnostic methods and treatment of children with esophageal burns according to the degree of the injury.

Methods: Our one-center population-based retrospective cohort study included 150 children admitted between 1967 and 2018 to Clinic of Pediatric Otolaryngology, Phoniatrics and Audiology of University Children's Hospital in Lublin, Poland, due to the chemical burn of the mouth, throat, larynx, and esophagus. Read More

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http://dx.doi.org/10.1177/0145561319843109DOI Listing
April 2019
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The Mealtime Assessment Scale (MAS): Part 2 - Preliminary Psychometric Analysis.

Folia Phoniatr Logop 2019 Apr 17:1-12. Epub 2019 Apr 17.

Department of Biomedical and Clinical Sciences "L. Sacco," Università degli Studi di Milano, Milan, Italy.

Aims: The Mealtime Assessment Scale (MAS) was developed to assess swallowing safety and efficacy during the meal. The study aims to perform a preliminary validation of MAS by investigating internal consistency, inter-rater agreement, concurrent and known-group validity, and responsiveness.

Methods: MAS was tested on 100 persons without dysphagia (group 1) and 100 persons with dysphagia (group 2). Read More

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http://dx.doi.org/10.1159/000494136DOI Listing

Oropharyngeal dysphagia in early stages of myotonic dystrophy type 1.

Muscle Nerve 2019 Apr 17. Epub 2019 Apr 17.

Laboratory of Genomic Medicine, Department of Genetics, National Rehabilitation Institute (INR-LGII), Mexico City, Mexico.

Introduction: Myotonic dystrophy type 1 (DM1) is a multisystemic disorder characterized mainly by skeletal muscle alterations. Althought oropharyngeal dysphagia is a prominent clinical feature of DM1, it remains poorly studied in its early disease stages.

Methods: Dysphagia was investigated in 11 pre-symptomatic DM1-carriers, 14 DM1 patients, and 12 age-matched healthy controls, using fiberoptic endoscopic evaluation of swallowing (FEES) and clinical scores. Read More

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http://dx.doi.org/10.1002/mus.26485DOI Listing
April 2019
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Hypercontractile esophageal motility disorder or functional esophageal symptoms and unrelated hypercontractility?

Neurogastroenterol Motil 2019 May;31(5):e13594

Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands.

In this issue of the journal, Mion and coworkers describe 23 patients with dysphagia and/or thoracic pain and hypercontractile esophageal motility disorders who were either treated with botulinum toxin 100 U or underwent a sham procedure. The surprising outcome of the study was that both active botulinum toxin treatment and sham treatment resulted in a significant reduction in symptoms and manometric abnormalities after 3 months, with no difference between the two arms. One can interpret the lack of effect of botulinum toxin over placebo as indicative of the benign natural history of hypercontractile esophageal motility disorders or be convinced that many patients with hypercontractility on manometry actually have functional symptoms not related to the manometric findings, and thus, treatment of hypercontractility is not more effective than placebo. Read More

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http://dx.doi.org/10.1111/nmo.13594DOI Listing
May 2019
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Chronic daily opioid exposure is associated with dysphagia, esophageal outflow obstruction, and disordered peristalsis.

Neurogastroenterol Motil 2019 Apr 17:e13601. Epub 2019 Apr 17.

Division of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, Wisconsin.

Background: Opioid receptors are present in the esophagus, and chronic opioid therapy may be associated with esophageal dysfunction. Given the current opioid epidemic in the United States, the potential contribution of opioids to esophageal dysmotility is important from both public health and patient care perspectives. Therefore our aim is to investigate the potential contribution of opioids to dysphagia and the prevalence of major motor disorders in patients undergoing manometric evaluation. Read More

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http://dx.doi.org/10.1111/nmo.13601DOI Listing
April 2019
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Ectopic Thyroid Mass Separately Present in Mediastinum and Not a Retrosternal Extension: A Report of Two Cases.

Case Rep Surg 2019 12;2019:3821767. Epub 2019 Mar 12.

Department of Surgery, The Aga Khan University Hospital, Karachi, Pakistan.

Retrosternal extension of goiter is one of the most common types of masses in the superior mediastinum. These types of goiters classically present with compressive symptoms such as dyspnea, dysphonia, dysphagia, or sleep apnea. Surgical treatment with a total thyroidectomy and complete removal of the intrathoracic portion of thyroid is the gold standard treatment. Read More

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https://www.hindawi.com/journals/cris/2019/3821767/
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http://dx.doi.org/10.1155/2019/3821767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434302PMC
March 2019
2 Reads

Safety and efficacy of cervical disc arthroplasty in preventing the adjacent segment disease: a meta-analysis of mid- to long-term outcomes in prospective, randomized, controlled multicenter studies.

Ther Clin Risk Manag 2019 28;15:531-539. Epub 2019 Mar 28.

Department of Bioengineering, Institute of Biomedical Engineering, Technical University of Wroclaw, Wroclaw, Poland.

Objectives: Cervical disc arthroplasty (CDA) has become an alternative treatment for cervical radiculopathy and myelopathy. This technique preserves appropriate motion at both the index and adjacent disc levels and consequently may prevent adjacent segment degeneration (ASD). The authors performed a meta-analysis to compare the safety and efficacy of CDA to those of the gold standard, anterior cervical discectomy and fusion (ACDF). Read More

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http://dx.doi.org/10.2147/TCRM.S196349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445235PMC
March 2019
2 Reads

The convergent validity of a Dutch Screening tool for Dysphagia (Signaleringslijst Verslikken) for people with severe or profound intellectual and multiple disabilities.

J Appl Res Intellect Disabil 2019 Apr 16. Epub 2019 Apr 16.

Faculty of Behavioural and Social Sciences, Department of Special Needs Education and Youth Care, University of Groningen, Groningen, The Netherlands.

Background: Dysphagia is potentially life-threatening and highly prevalent in people with severe/profound intellectual and multiple disabilities (SPIMD). The "Signaleringslijst Verslikken" (SV) is a frequently used Dutch screening tool to detect dysphagia. The aim was to examine the convergent validity of the SV for people with SPIMD. Read More

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http://dx.doi.org/10.1111/jar.12592DOI Listing

Prevalence and Associated Impacts of Cervical Esophageal Clearance Issues Post Chemoradiotherapy for Nasopharyngeal Carcinoma (NPC).

Dysphagia 2019 Apr 15. Epub 2019 Apr 15.

School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, QLD, Australia.

At present, the nature and extent of upper esophageal stage clearance issues following nonsurgical management of nasopharyngeal cancer (NPC) is not well elucidated. The aim of this study was to conduct an initial retrospective study of the prevalence and severity of upper esophageal clearance impairments in a cohort of patients post-NPC management. A secondary aim was to explore any observed relationship between severity of impairment with both (a) aspiration and (b) temporal oropharyngeal swallowing measures. Read More

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http://dx.doi.org/10.1007/s00455-019-10007-yDOI Listing
April 2019
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Correlation Between and Malocclusion in Rett Syndrome: A preliminary study.

Sultan Qaboos Univ Med J 2018 Nov 28;18(4):e489-e493. Epub 2019 Mar 28.

Department of Ear, Nose & Throat, University Hospital of Siena, Siena, Italy.

Objectives: Rett syndrome (RS) is a severe neurological developmental disorder characterised by stereotypical hand movements, epileptic seizures, craniofacial dysmorphism and digestive dysfunction. This study aimed to examine the correlation between the severity of malocclusion and in patients with RS.

Methods: This preliminary study was conducted at the Ear, Nose & Throat Clinic of the University Hospital of Siena, Siena, Italy, from January 2014 to December 2017. Read More

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https://journals.squ.edu.om/index.php/squmj/article/view/299
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http://dx.doi.org/10.18295/squmj.2018.18.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443277PMC
November 2018
2 Reads

Upper Esophageal Sphincter Dilation for Recalcitrant Dysphagia Secondary to Dermatomyositis.

Ear Nose Throat J 2019 Apr 15:145561319842511. Epub 2019 Apr 15.

1 Department of Otolaryngology, Head and Neck Surgery, Emory University, Atlanta, GA, USA.

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http://dx.doi.org/10.1177/0145561319842511DOI Listing
April 2019
1 Read

Rehabilitation following open partial laryngeal surgery: key issues and recommendations from the UK evidence based meeting on laryngeal cancer.

J Laryngol Otol 2019 Mar;133(3):177-182

Department of ENT,Royal Marsden NHS Foundation Trust,London,UK.

Background: It is recognised that a limited cohort of patients receive open partial laryngeal surgery in specific centres within the UK, so sharing information around key clinical issues and recommendations for practice is necessary to improve outcomes.

Methods: This position statement provides practice recommendations based on a synthesis of the available evidence presented at the 12th Evidence Based Management day on 'Laryngeal Cancer' and the ensuing discussions. Literature searches and critical analysis of available evidence were undertaken and triangulated with the clinical experience of the authors to develop these recommendations. Read More

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http://dx.doi.org/10.1017/S0022215119000483DOI Listing

[A comparative study of short- and long-term outcomes for transcervical versus transoral surgery for Zenker diverticulum].

Orv Hetil 2019 Apr;160(16):629-635

Sebészeti Klinika, Szegedi Tudományegyetem, Általános Orvostudományi Kar Szeged, Semmelweis u. 8., 6720.

Introduction And Aim: We present our experience with open (transcervical diverticulectomy, cricomyotomy) and transoral surgery (transoral stapler diverticulostomy) for Zenker diverticulums.

Method: Between 1 January 2006 and 31 December 2016, 29 patients were examined with a symptom-causing Zenker diverticulum. In 13 cases, transcervical surgery, in 16 cases, transoral surgery were performed. Read More

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http://dx.doi.org/10.1556/650.2019.31360DOI Listing
April 2019
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Evaluation of Oropharyngeal Dysphagia in Patients Who Underwent Percutaneous Endoscopic Gastrostomy: Stratification Risk of Pneumonia.

JPEN J Parenter Enteral Nutr 2019 Apr 14. Epub 2019 Apr 14.

Division of Pulmonary and Critical Care, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

Background: Aspiration pneumonia is the most common cause of death in patients who undergo percutaneous endoscopic gastrostomy (PEG). This study aims to evaluate the severity of oropharyngeal dysphagia and predict the risk of pneumonia in such patients, using upper gastrointestinal endoscopy.

Methods: Endoscope examined the pharyngolaryngeal region in patients who underwent PEG. Read More

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http://dx.doi.org/10.1002/jpen.1592DOI Listing
April 2019
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Brachytherapy in the Palliation of Oesophageal Cancer: Effective but Impractical?

Clin Oncol (R Coll Radiol) 2019 Apr 11. Epub 2019 Apr 11.

Clinical Effectiveness Unit, The Royal College of Surgeons of England, London, UK; Department of Health Services Research and Policy, London School of Hygiene & Tropical Medicine, London, UK.

Dysphagia in people with advanced oesophageal cancer can be treated by oesophageal stents, external beam radiotherapy (EBRT) and intraluminal brachytherapy. Despite guidelines recommending brachytherapy for patients with a predicted life expectancy exceeding 3 months, its uptake in the UK has been limited. Here we examine the strength of the evidence supporting the use of brachytherapy compared with oesophageal stents and EBRT and possible reasons for its limited uptake. Read More

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http://dx.doi.org/10.1016/j.clon.2019.03.045DOI Listing
April 2019
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The Prevalence of Dysphonia and Dysphagia in Patients with Vitamin D Deficiency.

J Voice 2019 Apr 11. Epub 2019 Apr 11.

Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon. Electronic address:

Objective: To investigate the prevalence of phonatory and swallowing symptoms in patients with hypovitaminosis D.

Methods/design: All patients presenting to the endocrinology clinic and investigated for vitamin D deficiency between January 2018 and April 2018 were asked to participate in this study. Demographic data included age, gender, allergy, and history of smoking. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08921997183049
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http://dx.doi.org/10.1016/j.jvoice.2019.03.007DOI Listing
April 2019
5 Reads

Opioid Treatment and Excessive Alcohol Consumption Are Associated With Esophagogastric Junction Disorders.

J Neurogastroenterol Motil 2019 Apr;25(2):205-211

Division of Gastroenterology and Hepatology, University Hospital Zurich, Switzerland.

Background/aims: The influence of external factors such as opioids and alcohol has been extensively investigated for various segments of the gastrointestinal tract. However, the association between their use and the development of esophagogastric junction outflow obstruction disorders (EGJOODs) is unknown. Therefore, the aim of this study is to analyze prevalence and clinical relevance of opioids and alcohol intake in patients with EGJOODs. Read More

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http://dx.doi.org/10.5056/jnm18150DOI Listing
April 2019
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Predictors of Oral Feeding Resumption after Stroke in a Rehabilitation Hospital: A Retrospective Study.

J Stroke Cerebrovasc Dis 2019 Apr 10. Epub 2019 Apr 10.

Department of Neurorehabilitation Sciences, Casa di Cura del Policlinico, Milano, Italy.

Background: Dysphagia is common after stroke, requiring exclusive enteral feeding in 20% of patients. Recovery of oral feeding is associated with increased quality of life, better functional outcomes, and decreased mortality rates. However, evidence is heterogeneous and not conclusive on which factors are predictive of oral feeding recovery for stroke patients in rehabilitation units. Read More

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2019.03.040DOI Listing
April 2019
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An Unusual Cause of Dysphagia in an Elderly Woman: Dysphagia Megalatriensis.

Am J Med Sci 2019 Feb 23. Epub 2019 Feb 23.

Department of Gastroenterology, Changhua Christian Hospital, Changhua, Taiwan; General Education Center, Chienkuo Technology University, Changhua, Taiwan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029629193008
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http://dx.doi.org/10.1016/j.amjms.2019.02.018DOI Listing
February 2019
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Impact Of The Occiput and External Acoustic Meatus to Axis (O-EA) Angle On Dysphagia In Patients Suffering from Anterior Atlantoaxial Subluxation after Occipitocervical Fusion.

Spine J 2019 Apr 10. Epub 2019 Apr 10.

Department of Orthopedics surgery, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China. Electronic address:

Background Context: Dysphagia is a complication that sometimes occurs after occipitocervical fusion (OCF). An appropriate O-C2 angle (O-C2a) is recognized as a critical factor for preventing dysphagia. The occiput and external acoustic meatus to axis angle (O-EAa) has some advantages over the O-C2a and is now recognized to outperform O-C2a in predicting dysphagia. Read More

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http://dx.doi.org/10.1016/j.spinee.2019.04.002DOI Listing
April 2019
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Lingual (Not Palatine) Tonsillolith: Case Report.

J Oral Maxillofac Surg 2019 Mar 19. Epub 2019 Mar 19.

Director, Salivary Gland Center; Associate Dean, Clinical Professor, Division of Oral and Maxillofacial Surgery, Columbia University College of Dental Medicine, New York, NY. Electronic address:

The lingual tonsil (LT), located at the base of the tongue posterior to the circumvallate papillae, consists of aggregates of lymphoid tissue separated by a median glossoepiglottic ligament that splits the LT into right and left halves. Tonsillar tissue on either side of the ligament exhibits discrete round nodules that project upward. Each prominence is covered by nonkeratinized epithelium and has a central crypt formed by an invagination of the overlying epithelium. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02782391193027
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http://dx.doi.org/10.1016/j.joms.2019.03.006DOI Listing
March 2019
2 Reads

Mucosal loss as a critical factor in esophageal stricture formation after mucosal resection: a pilot experiment in a porcine model.

Surg Endosc 2019 Apr 12. Epub 2019 Apr 12.

Department of Gastroenterology, First Affiliated Hospital of Zhengzhou University, No. 1 Eastern Jianshe Road, Zhengzhou, 450052, China.

Background And Aim: Esophageal stricture is a major complication of large areas endoscopic submucosal dissection (ESD). Until now, the critical mechanism of esophageal stricture remains unclear. We examined the role of mucosal loss versus submucosal damage in esophageal stricture formation after mucosal resection using a porcine model. Read More

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http://dx.doi.org/10.1007/s00464-019-06793-zDOI Listing
April 2019
1 Read

Effective treatment improves the body composition of patients with esophageal motility disorders.

Dis Esophagus 2019 Apr 12. Epub 2019 Apr 12.

Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, and.

Although treatment for esophageal motility disorder improves dysphagia and increases body weight, the effect of the treatment on body composition is unclear. This study aimed to assess the change in body composition between before and after treatment, the preoperative predictors of muscle increase, and the association between muscle increase and quality of life. Sixty-one patients (achalasia, n = 55; spastic esophageal disorder n = 6) who underwent per-oral endoscopic myotomy were analyzed in a single-arm prospective observational study. Read More

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https://academic.oup.com/dote/advance-article/doi/10.1093/do
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http://dx.doi.org/10.1093/dote/doz022DOI Listing
April 2019
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Effect of attention on chewing and swallowing behaviors in healthy humans.

Sci Rep 2019 Apr 12;9(1):6013. Epub 2019 Apr 12.

Division of Dysphagia Rehabilitation, Niigata University Graduate School of Medical and Dental Sciences, 2-5274 Gakkocho-dori, Chuo-ku, Niigata, 951-8514, Japan.

We examined how attention alters chewing and swallowing behaviors. Twenty-one healthy volunteers were asked to freely eat 8 g of steamed rice in three separate trials, and we obtained the average number of chewing cycles (N) and chewing duration (T) prior to the first swallow in each trial. We also conducted an N-limited test, in which participants chewed the food while independently counting the number of chewing cycles and swallowed the food when they reached N, and a T-limited test, in which they chewed the food for T sec and then swallowed. Read More

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http://www.nature.com/articles/s41598-019-42422-4
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http://dx.doi.org/10.1038/s41598-019-42422-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461604PMC
April 2019
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Spontaneous cervical chyle fistula: A case report.

Am J Otolaryngol 2019 Apr 2. Epub 2019 Apr 2.

Cleveland Clinic, Head and Neck Institute, Cleveland, OH, USA. Electronic address:

Background: Cervical chylous fistulae are rare complications usually occurring from iatrogenic injury to the thoracic duct. There have been no reported cases of spontaneous chyle leaks in surgical naïve necks.

Methods: Case report. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01960709193026
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http://dx.doi.org/10.1016/j.amjoto.2019.04.004DOI Listing
April 2019
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[Current Treatment of Achalasia 2019].

Zentralbl Chir 2019 Apr 12;144(2):163-170. Epub 2019 Apr 12.

Universitätsklinik für Chirurgie, Salzburger Landeskliniken, Salzburg, Österreich.

Treatment of primary idopathic achalasia, the most common of the rare oesophageal motility disorders, is currently changing. The therapeutic priciple of Heller's myotomy is increasingly accepted as standard. In 1913, the German surgeon Ernst Heller described the cardiomyotomy named after him, faciliating excellent symptom control. Read More

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http://dx.doi.org/10.1055/a-0863-4917DOI Listing
April 2019
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Evaluation of the efficacy of Hypericum perforatum (St. John's wort) oil in the prevention of stricture due to esophageal corrosive burns.

Esophagus 2019 Apr 11. Epub 2019 Apr 11.

Department of Pediatric Surgery, Kocaeli University Medical Faculty, Umuttepe, 41380, Kocaeli, Turkey.

Background/purpose: The inflammatory response that follows the caustic burns results in fibrosis on the esophageal wall leading to esophageal stricture, dysphagia, and malnutrition. The controversy over the use of corticosteroids warrants alternative therapeutic interventions. We investigated the effect of extracts from St. Read More

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http://dx.doi.org/10.1007/s10388-019-00671-2DOI Listing
April 2019
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Botulinum toxin for the treatment of hypercontractile esophagus: Results of a double-blind randomized sham-controlled study.

Neurogastroenterol Motil 2019 May 11;31(5):e13587. Epub 2019 Apr 11.

CHU Bordeaux, Gastroenterology, Université de Bordeaux, Bordeaux, France.

Introduction: Botulinum toxin injection is known to be efficient to treat achalasia. We conducted a randomized trial in order to evaluate its efficacy to treat symptomatic hypercontractile esophageal disorders as characterized by esophageal high-resolution manometry.

Methods: Patients with significant dysphagia and/or thoracic pain related to an hypercontractile esophageal motility disorder as defined by the Chicago Classification were randomized to receive an injection of botulinum toxin (100 U in 10 points in the distal part of the esophageal wall) or a sham procedure. Read More

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http://dx.doi.org/10.1111/nmo.13587DOI Listing
May 2019
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Ineffective esophageal motility: Concepts, future directions, and conclusions from the Stanford 2018 symposium.

Neurogastroenterol Motil 2019 Apr 11:e13584. Epub 2019 Apr 11.

Division of Gastroenterology, Stanford University, Stanford, California.

Background: Ineffective esophageal motility (IEM) is a heterogenous minor motility disorder diagnosed when ≥50% ineffective peristaltic sequences (distal contractile integral <450 mm Hg cm s) coexist with normal lower esophageal sphincter relaxation (integrated relaxation pressure < upper limit of normal) on esophageal high-resolution manometry (HRM). Ineffective esophageal motility is not consistently related to disease states or symptoms and may be seen in asymptomatic healthy individuals.

Purpose: A 1-day symposium of esophageal experts reviewed existing literature on IEM, and this review represents the conclusions from the symposium. Read More

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http://dx.doi.org/10.1111/nmo.13584DOI Listing
April 2019
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Association of GSTP1 and ERCC1 polymorphisms with toxicity in locally advanced head and neck cancer platinum-based chemoradiotherapy treatment.

Head Neck 2019 Apr 11. Epub 2019 Apr 11.

Pharmacy Department, University Hospital of Santiago (SERGAS), Santiago de Compostela, Spain.

Background: Platinum-based chemoradiotherapy (CRT) is the standard treatment for locally advanced head and neck squamous-cell carcinomas (HNSCC), and most patients experience serious toxicities. The aim of this study was to investigate the association between candidate genes involved in radiation/platinum pathways and acute toxicity of CRT to determine the predictive value of these polymorphisms for toxicity.

Methods: Thirty-six selected single nucleotide polymorphisms (SNPs) in 29 genes were genotyped in 110 patients treated with cisplatin-based CRT. Read More

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http://dx.doi.org/10.1002/hed.25754DOI Listing
April 2019
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Hypersalivation: update of the German S2k guideline (AWMF) in short form.

J Neural Transm (Vienna) 2019 Apr 10. Epub 2019 Apr 10.

Department for Otorhinolaryngology, University of Luebeck, Ratzeburger Allee 120, 23538, Lübeck, Germany.

Hypersalivation describes a relatively excessive salivary flow, which wets the patient himself and his surroundings. It may result because of insufficient oro-motor function, dysphagia, decreased central control and coordination. This update presents recent changes and innovation in the treatment of hypersalivation. Read More

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http://dx.doi.org/10.1007/s00702-019-02000-4DOI Listing
April 2019
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Disappearance of Anterior Cervical Corpectomy Cage.

Cureus 2019 Jan 30;11(1):e3985. Epub 2019 Jan 30.

Neurosurgery, Taipei Veterans General Hospital, Taipei, TWN.

Although cage subsidence and dislodgement are not uncommon in anterior cervical spine surgery, missing cages have seldom been reported. This is the first report of the disappearance of a metallic corpectomy cage after anterior cervical fusion. A 63-year-old man, who had a history of ankylosing spondylitis and diabetes mellitus, was involved in a motor vehicle accident that broke his neck. Read More

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https://www.cureus.com/articles/17446-disappearance-of-anter
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http://dx.doi.org/10.7759/cureus.3985DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443108PMC
January 2019
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The Shaking Palsy of the Larynx-Potential Biomarker for Multiple System Atrophy: A Pilot Study and Literature Review.

Front Neurol 2019 26;10:241. Epub 2019 Mar 26.

Hospital for Movement Disorders/Parkinson's Disease, Beelitz-Heilstätten, Germany.

In its early stages multiple system atrophy (MSA), a neurodegenerative movement disorder, can be difficult to differentiate from idiopathic Parkinson's disease (PD), and emphasis has been put on identifying premotor symptoms to allow for its early identification. The occurrence of vegetative symptoms in addition to motor impairment, such as orthostatic hypotension and neurogenic bladder dysfunction, enable the clinical diagnosis in the advanced stages of the disease. Usually with further disease progression, laryngeal abnormalities become clinically evident and can manifest in laryngeal stridor due to impaired vocal fold motion, such as vocal fold abduction restriction, mostly referred to as vocal fold paresis, or paradoxical vocal fold adduction during inspiration. Read More

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http://dx.doi.org/10.3389/fneur.2019.00241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443854PMC
March 2019
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Gliclazide Prevents 5-FU-Induced Oral Mucositis by Reducing Oxidative Stress, Inflammation, and P-Selectin Adhesion Molecules.

Front Physiol 2019 26;10:327. Epub 2019 Mar 26.

Postgraduate Oral Science, Postgraduate Programs in Pharmaceutical Science, Department of Biophysics and Pharmacology, Federal University of Rio Grande Norte, Natal, Brazil.

Oral mucositis (OM) is one of the main side effects of the head and neck cancer treatment, particularly radiotherapy and/or chemotherapy. OM is characterized by ulcers, erythema, dysphagia, xerostomia, and increased susceptibility to opportunistic infections. In the perspective of finding pharmacological therapies to prevent inflammation and ulceration of OM, the investigation of the pleiotropic effect of commercial drugs is needed, among them gliclazide, an antidiabetic drug. Read More

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http://dx.doi.org/10.3389/fphys.2019.00327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445135PMC
March 2019
2 Reads