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J Minim Invasive Gynecol 2019 Apr 17. Epub 2019 Apr 17.

Department of Obstetrics and Gynecology, University of South Florida, Morsani College of Medicine, Tampa, FL. Electronic address:

Study Objective: To compare the detection rate of adenomyosis when ultrasound is performed by a radiologist compared to a gynecologic expert sonologist.

Design: A retrospective, single center study.

Setting: University teaching hospital PATIENTS: All women above 18 years of age with a positive histopathology diagnosis of adenomyosis obtained in a hysterectomy specimen from October 1, 2011 - October 1, 2017 were screened for inclusion. Read More

J Obstet Gynaecol Can 2019 Apr 16. Epub 2019 Apr 16.

Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB. Electronic address:

Objective: Combined oral contraceptives (COC) are a popular choice among women. The Internet is an accessible and popular source of information on contraception. The objective of this study was to evaluate the quality of online information on COC. Read More

J Ethnopharmacol 2019 Apr 15:111883. Epub 2019 Apr 15.

Laboratory of Biology, Department of Animal Biology and Physiology, Faculty of Science, University of Yaoundé I, P.O. Box 812, Yaoundé, Cameroon; Centre for Schistosomiasis and Parasitology, P.O. Box 7244, Yaoundé, Cameroon. Electronic address:

Ethnopharmacological Relevance: Ozoroa pulcherrima Schweinf. (syn.: Heeria pulcherrrima Schweinf. Read More

Int J Hyperthermia 2019 Apr 17:1-7. Epub 2019 Apr 17.

a Department of Gynecology, Shanghai First Maternity and Infant Hospital , Tongji University School of Medicine , Shanghai , PR China.

Objective: To evaluate the combined efficacy of high-intensity focused ultrasound (HIFU), gonadotropin-releasing hormone agonist (GnRH-a) and the levonorgestrel-releasing intrauterine system (LNG-IUS) for the treatment of severe adenomyosis.

Method: Four hundred and sixty-six patients with adenomyosis admitted to the Department of Gynecology of Shanghai First Maternity and Infant Hospital underwent HIFU treatment, and then were consecutively administered with GnRH-a 1 d, 1 month and 3 months after HIFU treatment. The uterine size was then measured with ultrasound or MRI 2-4 weeks after three cycles of GnRH-a injection. Read More

Fertil Steril 2019 Apr 13. Epub 2019 Apr 13.

Augusta University, Augusta, Georgia.

Objective: To evaluate the efficacy of elagolix, an oral GnRH antagonist, for the reduction of fatigue in women with moderate or severe endometriosis-associated pain.

Design: Randomized, double-blind, multicenter, placebo-controlled phase III trial.

Setting: Clinics. Read More

Rev Bras Ginecol Obstet 2019 Mar 16;41(3):170-175. Epub 2019 Apr 16.

University of Siena, Siena, Italy.

Objective:  Endometriosis is a complex disease, and pain is an important component of the syndrome. One of the most used methods to assess pain is the visual analogue scale (VAS). The aim of the present research was to study the pain experienced by patients who referred to our unit for endometriosis, using the VAS to understand the variables that could influence it. Read More

Altern Ther Health Med 2019 Mar;25(2):22-38

Insulin resistance (IR) is defined as the inability of a known quantity of exogenous or endogenous insulin to increase glucose uptake and utilization. Several mechanisms have been proposed as possible causes underlying the development of IR and the IR syndrome. IR occurs as part of a cluster of cardiovascular-metabolic abnormalities commonly referred to as "The Metabolic Syndrome. Read More

Zhongguo Zhong Yao Za Zhi 2019 Feb;44(3):559-565

Pharmacy College, Chengdu University of Traditional Chinese Medicine Chengdu 611137, China.

This paper aimed to predict and explore the mechanism of multiple components, targets and pathways of Siwu decoction for treatment of primary dysmenorrhea, and to establish a network pharmacological model of "compound-target-pathway-disease". According to the active ingredients in Siwu Decoction, Swiss Target Prediction server was used to predict the active component targets based on the reverse pharmacodynamic group matching method, and the primary dysmenorrhea targets approved by FDA were selected by database including DrugBank, OMIM and TTD. According to the enrichment analysis of the target pathways by using KEGG, the Cytoscape software was used to construct the network of "compound-target-pathway-disease" of Siwu Decoction. Read More

J Ethnopharmacol 2019 Apr 12:111874. Epub 2019 Apr 12.

Department of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea; Biomedical Center for Animal Resource and Development, Seoul National University College of Medicine, Seoul, Republic of Korea; Graduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea; Designed Animal and Transplantation Research Institute, Institute of GreenBio Science Technology, Seoul National University, Pyeongchang-gun, Gangwon-do, Republic of Korea. Electronic address:

Ethnopharmacology Relevance: Dendropanax morbifera Leveille (DM) has been used in traditional medicines for infectious and skin diseases, and dysmenorrhea. It exhibits a diverse therapeutic potential including anti-cancer, anti-thrombotic, anti-diabetic, anti-oxidant, and anti-inflammatory activities.

Aim Of The Study: Despite promising health benefits of DM, knowledge of its potential adverse effects is very limited. Read More

J Family Med Prim Care 2019 Feb;8(2):640-647

Department of Paediatrics, Pramukhswami Medical College, Karamsad, Gujarat, India.

Aim Of Study: We assessed the prevalence and severity of premenstrual syndrome (PMS) in adolescents and identified probable associations of PMS and premenstrual dysphoric disorder (PMDD) with age, locality, food habits, obesity, stress, genetic influence, menorrhagia and dysmenorrhoea.

Methods: Cross-sectional study in schools of Anand District in State of Gujarat, India. We conducted the study in 1702 girls in the age group of 8-23 years who had achieved menarche. Read More

Open Access Maced J Med Sci 2019 Mar 28;7(6):920-924. Epub 2019 Mar 28.

University of Medicine and Health Sciences, Basseterre, St. Kitts and Nevis.

Background: Dysmenorrhea occurs as one of the symptoms of menstruation. While not necessarily a condition that plagues every woman, it is known to cause significant distress. Absenteeism from school and work as well as general discomfort are some of its adverse effects. Read More

Acta Obstet Gynecol Scand 2019 Apr 10. Epub 2019 Apr 10.

Department of Obstetrics and Gynecology, Aarhus University Hospital, Aarhus, Denmark.

Introduction: Deep infiltrating endometriosis is a common cause of pelvic pain. However, some patients have limited problems that may be controlled by medical treatment, thus avoiding potentially severe complications to major surgery. This approach requires detailed knowledge on the quality of life and clinical symptoms over time. Read More

BMJ Open 2019 Apr 8;9(4):e026643. Epub 2019 Apr 8.

Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, Shanghai, China.

Objectives: To investigate the association between tea drinking and dysmenorrhoea among women of reproductive age.

Design: A cross-sectional study based on Shanghai Birth Cohort Study.

Setting: Two preconceptional care clinics in Shanghai, China. Read More

Gynecol Endocrinol 2019 Apr 7:1-5. Epub 2019 Apr 7.

a Student Research Committee, School of Health , Qazvin University of Medical Sciences , Qazvin , Iran.

Primary dysmenorrhea is a common gynecologic disorder and is one of the main causes for referral to the gynecology clinic. This study aimed to determine the effects of alpha-lipoic acid (ALA) and mefenamic acid and a combination compared with placebo on the girls with primary dysmenorrhea. This double-blind, placebo-controlled clinical trial done on population consisted of female students living in dormitories of Qazvin University of Medical Sciences who had moderate to severe dysmenorrhea using the Visual Analog Scale (VAS) questionnaire. Read More

Zhongguo Zhen Jiu 2019 Apr;39(4):367-70

the Eighth Hospital Affiliated to Sun Yat-Sen University, Shenzhen 518033, Guangdong Province.

Objective: To explore the clinical effects on primary dysmenorrhea treated with moxibustion at Shenque (CV 8) and warm needling at Guanyuan (CV 4) and Sanyinjiao (SP 6).

Methods: A total of 120 patients with primary dysmenorrhea were randomized into an observation group and a control group, 60 cases in each one. In the control group, the warm needling technique was used at Guanyuan (CV 4) and Sanyinjiao (SP 6). Read More

Sex Med 2019 Apr 3. Epub 2019 Apr 3.

BC Women's Center for Pelvic Pain and Endometriosis, Vancouver, British Columbia, Canada; Women's Health Research Institute, Vancouver, British Columbia, Canada; Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, British Columbia, Canada; BC Centre for Vulvar Health, Vancouver, British Columbia, Canada. Electronic address:

Introduction: Pelvic pain and vulvar pain are common conditions in women. In this study, we sought to characterize the clinical picture of patients with concurrent pelvic pain and provoked vestibulodynia (PVD).

Aim: To analyze the association between sexual/clinical characteristics and a diagnosis of PVD among women with pelvic pain. Read More

Mater Sci Eng C Mater Biol Appl 2019 Jul 24;100:276-285. Epub 2019 Feb 24.

Lovely School of Pharmaceutical Sciences, Lovely Professional University, Jalandhar-Delhi, G.T.Road (NH-1), Phagwara, Jalandhar, Punjab 144411, India; National Institute of Pharmaceutical Education and Research (NIPER)-Guwahati, C/O NETES Institute of Technology & Science, NH-37, Santipur, Parli Part, Mirza, Assam 781125, India. Electronic address:

Ginger (GIN) powder-loaded oil-in-water (o/w) macroemulsions were prepared based on olive-and silicone-oils. The dispersed oil droplets with paired-beans structure were evident and thus the final emulsion can be termed as Janus macroemulsions. The objectives of the present study are (1) to identify the marker compound present in GIN powder via HPLC analysis, (2) to process the GIN powder via anti-solvent precipitation technique, (3) to see the solubility of GIN powder in various single oils or oil combination, (4) to optimize the GIN-loaded o/w macroemulsions using the central composite design (CCD) with respect to mean particle size of dispersed oil droplets and highest percentage drug entrapment efficiency values (DEE) and (5) to evaluate the pain reducing activity of optimized GIN-loaded macroemulsion via in vivo primary dysmenorrhea (PD) mice model. Read More

J Am Med Inform Assoc 2019 Apr 4. Epub 2019 Apr 4.

Interdisciplinary Program of Medical Informatics, Seoul National University, Seoul, Korea.

Objective: Most healthcare providers are reluctant to use health apps for healthcare because there is no rigorous way of choosing the best app for their patient or consumer. Accordingly, we developed a new method of app selection that fully considers target users' needs. This study verified whether health apps selected based on target users' needs can influence health-related factors. Read More

Medicine (Baltimore) 2019 Apr;98(14):e15100

School of Preclinical Medicine, Beijing University of Chinese Medicine, Beijing, China.

Introduction: Chinese herbal medicines (CHM) have been commonly used in the treatment of primary dysmenorrhea in East Asia. Several systematic reviews have been conducted to assess the clinical efficacy of CHM in the treatment of primary dysmenorrhea. However, their comparative efficacy is still unclear. Read More

Neurourol Urodyn 2019 Apr 4. Epub 2019 Apr 4.

Department of Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin.

Aims: The neuropathophysiology of a debilitating chronic urologic pain condition, bladder pain syndrome (BPS), remains unknown. Our recent data suggests withdrawal of cardiovagal modulation in subjects with BPS, in contrast to sympathetic nervous system dysfunction in another chronic pelvic pain syndrome, myofascial pelvic pain (MPP). We evaluated whether comorbid disorders differentially associated with BPS vs MPP shed additional light on these autonomic differences. Read More

Zhen Ci Yan Jiu 2019 Feb;44(2):120-4

School of Acupuncture-moxibustion and Massage, Guiyang College of Traditional Chinese Medicine, Guiyang 550002, China.

Objective: To observe the effect of herbal-cake-partitioned moxibustion (HCPM) of "Shenque" (CV8) and "Daheng" (SP15) on abdominal pain, plasma β-endorphin (β-EP), uterine prostaglandin E (PGE) and prostaglandin F (PGF) levels, as well as splenetic natural killer cell (NK cell) activity in primary dysmenorrhea (PD) rats, so as to explore the specificity of acupoint function and the underlying mechanisms of moxibustion in relieving dysmenorrhea.

Methods: A total of 40 female rats were randomized into blank control, model, CV8-direct moxibustion, CV8-HCPM and SP15-HCPM groups (＝8 rats in each). The PD model was established by subcutaneous injection of estradiol benzoate injection (0. Read More

J Pediatr Adolesc Gynecol 2019 Mar 25. Epub 2019 Mar 25.

Department of Pediatrics, Harvard Medical School, 25 Shattuck Street, Boston, MA, USA, 02115. Electronic address:

Use of marijuana in adolescent girls is common and showing no sign of decreasing. With recent trends towards legalization of "recreational" and "medical" marijuana products, adolescents are increasingly faced with information and misinformation about the health effects of marijuana use. We review the current literature on the risks and potential benefits of marijuana use during adolescence with a specific focus on pediatric and adolescent gynecological conditions. Read More

Nurs Open 2019 Apr 27;6(2):268-275. Epub 2018 Sep 27.

Clarke International University School of Nursing Kampala Uganda.

Aim: Dysmenorrhoea presents as pain associated with menstruation. It is often an issue discussed privately, yet it continues to affect girls and women with grave impact on their education, social activities and work. This study sought to assess the factors associated with dysmenorrhoea among female students aged 18-45 years in three selected universities in Kampala Capital city, Uganda. Read More

J Obstet Gynaecol Res 2019 Mar 25. Epub 2019 Mar 25.

Department of Obstetrics and Gynecology of Shanghai Medical School, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, People's Republic of China.

Aim: Previous studies have revealed that loss of cell apical-basal polarity contributed to the early stages of tumorigenesis. Adenomyosis involves a down-growth and aberrant implantation of the endometrial basalis into the myometrium. This study discovered aberrant expression of polarity protein Scribble (Scrib) and Crumbs homologue 3 protein (CRB3) in epithelial cells of diffuse adenomyosis. Read More

J Family Med Prim Care 2019 Jan;8(1):137-140

Department of Preventive and Social Medicine, JIPMER, Puducherry, India.

Background: Menstrual disorders are common among women in reproductive age group and affect their normal functioning and social life. Due to cultural reasons, menstrual problems often get unreported. In India, the literature on the effect of menstrual disorders on the quality of life (QOL) of women is limited. Read More

Taiwan J Obstet Gynecol 2019 Mar;58(2):227-233

Department of Persian Medicine, School of Persian Medicine, Babol University of Medical Sciences, Babol, Iran; Traditional Medicine and History of Medical Sciences Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran. Electronic address:

Objective: This study strove to investigate the safety and effectiveness of Eryngo in the treatment of primary dysmenorrhea.

Materials And Methods: The researchers conducted a blinded, randomized, trial design on 169 women, 15-30 years of age, who had been diagnosed with primary dysmenorrhea at Babol University of Medical Sciences. Subjects were randomly assigned to receive 5 ml syrup of Eryngo, placebo, or Ibuprofen (200 mg) three times a day (15 ml/day), from one day prior to the onset of bleeding for five days. Read More

BMJ Open 2019 Mar 20;9(3):e023582. Epub 2019 Mar 20.

School of Public Health, Curtin University, Perth, Western Australia, Australia.

Introduction: A review of international and Australian school-based resources suggests that teaching of the ovulatory-menstrual (OM) cycle is predominantly couched in biology. A whole-person framework that integrates spiritual, intellectual, social and emotional dimensions with the physical changes of the OM cycle is needed to facilitate adolescent OM health literacy. This paper describes the protocol for a study that aims to develop and trial an intervention for adolescent girls aged 13-16 years that enhances positive attitudes towards OM health coupled with developing skills to monitor and self-report OM health. Read More

J Gynecol Obstet Hum Reprod 2019 Mar 18. Epub 2019 Mar 18.

Student Research Committee, School of Health, Qazvin University of Medical Sciences, Qazvin, Iran; Metabolic Diseases Research Center, Qazvin University of Medical Sciences, Qazvin, Iran. Electronic address:

Dysmenorrhea, also known as painful periods, or menstrual cramps, is pain during menstruation. This study was done in young women that assess the association of serum vitamin D concentration and severity of dysmenorrhea pain. This descriptive-analytic study conducted on young girls referred to Shahid fakuri clinic in Tehran. Read More

Arch Gynecol Obstet 2019 May 19;299(5):1305-1312. Epub 2019 Mar 19.

Department of gynecology and obstetrics, Shiraz University of Medical Sciences, Shiraz, Iran.

Purpose: Studies showed anti-inflammatory and immunomodulatory effects of macrolide antibiotics such as clarithromycin in endometriosis. Therefore, the present study aims to investigate the therapeutic efficacy of clarithromycin in patients with endometriosis.

Methods: This was a double-blinded randomized placebo-controlled trial conducted on endometriotic women during March 2016-2017 in Dena Hospital, Shiraz, Iran. Read More

J Minim Invasive Gynecol 2019 Mar 15. Epub 2019 Mar 15.

Department of Obstetrics and Gynaecology (Mr. Kent), Royal Surrey County University NHS Hospital Trust, Guildford, United Kingdom.

Study Objective: To examine whether existing quality of health outcome measures can be used to predict or have an association with nonresponse surgery for endometriosis.

Design: Retrospective cohort study.

Settings: Single endometriosis referral center. Read More

Am J Obstet Gynecol 2019 Mar 15. Epub 2019 Mar 15.

Department of Obstetrics and Gynaecology, Rijnstate Hospital, Arnhem, The Netherlands.

Background: Menstrual symptoms such as dysmenorrhea, heavy menstrual bleeding, and perimenstrual mood disorders are known to be widespread among the general population. From studies in patients with endometriosis and premenstrual disorder, it has been shown that these symptoms can have a large impact on women's quality of life and account for substantial health care use. Furthermore, it is estimated that many women initially do not consult a doctor while facing menstrual symptoms. Read More

BMC Pediatr 2019 Mar 18;19(1):80. Epub 2019 Mar 18.

Department of Community Medicine and Behavioural Sciences, Faculty of Medicine, Kuwait University, Box: 24923, 13110, Safat, Kuwait.

Background: Although dysmenorrhea is not a life-threatening condition, it can cause a substantial burden on individuals and communities. There is no data on the prevalence of dysmenorrhea in Kuwait. This study aimed to estimate the prevalence of dysmenorrhea among female public high-school students in Kuwait and investigate factors associated with dysmenorrhea. Read More

Medicine (Baltimore) 2019 Mar;98(11):e14579

Department of Gynecology, Second Hospital of Hebei Medical University, Shijiazhuang, China.

To evaluate the clinical efficacy and safety of adenomyomectomy using "H" type incision combined with Mirena (LNG-IUS) in the treatment of adenomyosis.A total of 57 women with adenomyosis who underwent adenomyomectomy using "H" type incision combined with LNG-IUS were selected. Visual analog scale (VAS), menstrual flow, uterine volume, serum CA125 levels and hemoglobin amounts were compared before and after the surgery. Read More

Geburtshilfe Frauenheilkd 2019 Mar 12;79(3):286-292. Epub 2019 Mar 12.

Frauenklinik, Kantonsspital Frauenfeld, Frauenfeld, Switzerland.

The study's objectives were to determine the success rate following radiofrequency endometrial ablation to treat abnormal menstrual bleeding and to assess risk factors for failure of the method. 195 women who were treated with bipolar radiofrequency endometrial ablation between 01/2009 and 06/2016 were included in this prospective cohort study. Postoperative data from 187 women were collected at a median of 17. Read More

World J Clin Cases 2019 Mar;7(5):676-683

Department of Obstetrics and Gynecology, the First Hospital of Jilin University, Changchun 130021, Jilin Province, China.

Background: Cystic adenomyosis is a special type of adenomyosis. Its clinical manifestations lack specificity. Pelvic ultrasound and nuclear magnetic resonance imaging can help clarify the diagnosis. Read More

Sleep 2019 Mar 7. Epub 2019 Mar 7.

Shandong University School of Public Health, Jinan, China.

Study Objectives: Menstrual problems and daytime sleepiness are prevalent in adolescent girls. Little is known about the associations between age at menarche, menstrual problems and daytime sleepiness. This study aimed to examine the associations of age at menarche and menstrual problems with daytime sleepiness among Chinese adolescent girls. Read More

Oral Surg Oral Med Oral Pathol Oral Radiol 2019 Feb 6. Epub 2019 Feb 6.

Associate Professor, Department of Oral Medicine and Pathology, Faculty of Dentistry, National and Kapodistrian University of Athens, Athens, Greece. Electronic address:

Objective: The aim of this study was to describe 2 patients with piroxicam-associated fixed drug eruption on the tongue and to review the literature.

Study Design: Two females presented with recurrent ulcers after taking piroxicam for dysmenorrhea and pelvic pain. The English language literature was reviewed for cases of piroxicam-induced fixed drug eruptions, with a report on the site of occurrence. Read More

World J Clin Cases 2019 Feb;7(4):441-451

Division of Colon and Rectal Surgery, Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul 05505, South Korea.

Background: Endometriosis is a common disease for women of reproductive age. However, when it involves intestines, it is difficult to diagnose preoperatively because its symptoms overlap with other diseases and the results of evaluations can be unspecific. Thus it is important to know the clinical characteristics of intestinal endometriosis and how to exactly diagnose. Read More

J Sep Sci 2019 Mar 6. Epub 2019 Mar 6.

School of pharmacy, China Medical University, Shenyang, P. R. China.

Leonurus japonicus houtt, a well-known herb of traditional Chinese medicine, is widely used to treat gynaecological diseases. In this study, a rapid and sensitive liquid chromatography with tandem mass spectrometry method for simultaneously quantifying leonurine and stachydrine, the two main bioactive components in Leonurus japonicus houtt, was developed and validated. Plasma samples were prepared by protein precipitation with acetonitrile and separation by a Hewlett Packard XDB-C8 column (150 × 4. Read More

BMC Pregnancy Childbirth 2019 Mar 4;19(1):85. Epub 2019 Mar 4.

Department of Obstetrics and Gynaecology, Research institutes 'Amsterdam Cardiovascular Sciences' and 'Amsterdam Reproduction and Development', Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, Netherlands.

Background: Double-layer compared to single-layer closure of the uterus after a caesarean section (CS) leads to a thicker myometrial layer at the site of the CS scar, also called residual myometrium thickness (RMT). It possibly decreases the development of a niche, which is an interruption of the myometrium at the site of the uterine scar. Thin RMT and a niche are associated with gynaecological symptoms, obstetric complications in a subsequent pregnancy and delivery and possibly with subfertility. Read More

Reprod Sci 2019 Mar 4:1933719119833483. Epub 2019 Mar 4.

1 Department of Minimally Invasive Gynecologic Center, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, People's Republic of China.

The myometrium, especially the junctional zone (JZ), is now well documented to have a role in the pathogenesis of adenomyosis. Cannabinoid receptors have been shown to participate in the establishment of endometriosis and its pain perception. However, its relation to adenomyosis has not been identified yet. Read More

South Med J 2019 Mar;112(3):174-179

From the Vanderbilt-Meharry Center of Excellence in Sickle Cell Disease, Vanderbilt University Medical Center, Nashville, Tennessee, Rodeghier Consultants, Chicago, Illinois, Wayne State University, Detroit, Michigan, and Obstetrics and Gynecology, Duke Hemostasis and Thrombosis Center, Duke University, Durham, North Carolina.

Objectives: Women with sickle cell disease (SCD) are living longer as a result of advances in the care of their underlying disease. With the population growing of women living with SCD, reproductive health issues in this population have become an emphasized area of medical care. We sought to describe current patterns of contraception use, menstruation, and quality-of-life (QOL) measures in women with SCD. Read More

J Ethnopharmacol 2019 May 28;236:277-287. Epub 2019 Feb 28.

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, PR China.

Ethnopharmacological Relevance: Yuanhu Zhitong prescription (YZP) is a commonly used and relatively simple clinical herb preparation recorded in the China Pharmacopoeia. It contains Corydalis yanhusuo (Chinese name, Yanhusuo [YH]) and Angelica dahurica (Hoffm.) (Chinese name, Baizhi [BZ]), and has a long history of use in traditional Chinese medicine (TCM) for the treatment of stomach pain, hypochondriac pain, headache, and dysmenorrhea. Read More

Int J Environ Res Public Health 2019 Feb 27;16(5). Epub 2019 Feb 27.

Department of Nursing, Physiotherapy and Occupational Therapy, Faculty of Nursing of Ciudad Real, Universidad de Castilla-La-Mancha, Spain.

(1) Background: Primary dysmenorrhea, which is characterized by menstrual pain in the absence of a pelvic pathology, is one of the main reasons for gynecological consultation. This study aimed to assess the prevalence of dysmenorrhea in a sample of university students, as well as their quality of life, and to examine the most common methods used for alleviating symptoms. (2) Methods: The participants comprised 305 female university students with a mean age of 20. Read More

Sci Rep 2019 Feb 18;9(1):2194. Epub 2019 Feb 18.

Department of Obstetrics and Gynecology, NorthShore University HealthSystem, Evanston IL, 60201, USA.

Menstrual pain, also known as dysmenorrhea, is a leading risk factor for bladder pain syndrome (BPS). A better understanding of the mechanisms that predispose dysmenorrheic women to BPS is needed to develop prophylactic strategies. Abnormal autonomic regulation, a key factor implicated in BPS and chronic pain, has not been adequately characterized in women with dysmenorrhea. Read More

BMC Womens Health 2019 Feb 18;19(1):35. Epub 2019 Feb 18.

Department of Obstetrics and Gynaecology, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang, Street, Ouhai District, Wenzhou, Zhejiang Province, 325000, People's Republic of China.

Background: Until now, no previous study has addressed the menstrual patterns among female international students in China. In this present study, our objectives are to ascertain the menstrual characteristics and address the menstrual problems together with their associated risk factors among international students in China.

Methods: A cross-sectional survey was carried out with 500 previously piloted self-structured questionnaires which were administered to female international students enrolled in 15 universities in Zhejiang Province, China from May 2-August 31, 2016. Read More

Int J Reprod Biomed (Yazd) 2018 Nov;16(11):665-678

Department of Epidemiology and Reproductive Health, Reproductive Epidemiology Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.

Background: Understanding the prevalence of menstrual disorders has important implications for both health service planning and risk factor epidemiology.

Objective: The aim of this review is to identify and collate studies describing the prevalence of menstrual disorders in Iran.

Materials And Methods: Studies with original data related to the prevalence of menstrual disorders were identified via searching six electronic databases and reviewing citations. Read More

Prz Menopauzalny 2018 Dec 31;17(4):141-143. Epub 2018 Dec 31.

3 Chair and Department of Gynaecology, Medical University of Lublin, Lublin, Poland.

Uterine fibroids are considered to be the most common benign tumours in females. The vast majority of these tumours are incidental findings and do not require any treatment. Symptomatic fibroids, with ailments such as abnormal uterine bleeding, dysmenorrhoea, pelvic pain, impaired urination, bowel dysfunction, infertility, and recurrent pregnancy loss, are indicated for medical treatment. Read More

Neuroreport 2019 Mar;30(5):363-368

Department of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine.

Neuroimaging studies have manifested functional abnormalities in pain-related brain regions in patients with primary dysmenorrhea (PDM). However, as the key region in brain pain matrix, whether and how the amygdala functional network alteration in PDM is unclear. In this study, we aimed to investigate the intrinsic amygdala functional connectivity (AFC) network alteration in patients with PDM during ovulatory period. Read More

Int Braz J Urol 2019 Jan 25;45. Epub 2019 Jan 25.

Department of Gynae-Oncology, Asian Cancer Institute, Mumbai, India.

We demonstrate robot assisted radical nephrectomy with hysterectomy in the same sitting position followed by specimen retrieval per vagina (NOSE- Natural Orifice Specimen Extraction) A 36 year old female P2L2, presented with long standing dysmenorrhoea. Abdominal sonography detected incidental large left renal mass with a large fundal fibroid. CT scan revealed 8cmx8cm mass arising from mid and lower zone of the left kidney without vascular invasion and lymphadenopathy with a large fundal fibroid. Read More