6,497 results match your criteria Dysmenorrhea


Ginsenoside Rf alleviates dysmenorrhea and inflammation through the BDNF-TrkB-CREB pathway in a rat model of endometriosis.

Food Funct 2018 Dec 14. Epub 2018 Dec 14.

Department of Obstetrics and Gynecology, Shandong University QiLu Hospital, 104 culture west Road, Jinan 250012, Shandong, China.

To investigate the effects and the underlying mechanisms of ginsenoside Rf in a surgically induced rat endometriosis model, endometriosis was constructed through homologous transplantation and the Wistar rats were further randomly classified into the sham group, the estradiol valerate (E2V) control group, the endometriosis group, and the ginsenoside Rf groups (1.0, 2.0 and 4. Read More

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December 2018

Effect of Ginger and Novafen on menstrual pain: A cross-over trial.

Taiwan J Obstet Gynecol 2018 Dec;57(6):806-809

Department of Midwifery, Babol University of Medical Sciences, Babol, Islamic Republic of Iran.

Objective: Menstrual pain is a periodic pain which happens during the days of menses. The menstrual disturbances as a health problem among young girls affect not only reproductive, but also psychical health and quality of life. This study was done with the goal of comparing the effect of Ginger and Novafen on the menstrual pain. Read More

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December 2018

Interactions of Val66Met Polymorphism and Menstrual Pain on Brain Complexity.

Front Neurosci 2018 20;12:826. Epub 2018 Nov 20.

Institute of Brain Science, National Yang-Ming University, Taipei, Taiwan.

The irregularity and uncertainty of neurophysiologic signals across different time scales can be regarded as neural complexity, which is related to the adaptability of the nervous system and the information processing between neurons. We recently reported general loss of brain complexity, as measured by multiscale sample entropy (MSE), at pain-related regions in females with primary dysmenorrhea (PDM). However, it is unclear whether this loss of brain complexity is associated with inter-subject genetic variations. Read More

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November 2018

LATE IMPACT OF THE LAPAROSCOPIC TREATMENT OF DEEP INFILTRATING ENDOMETRIOSIS WITH SEGMENTAL COLORECTAL RESECTION.

Arq Bras Cir Dig 2018 Dec 6;31(4):e1406. Epub 2018 Dec 6.

Medical School, University of Southern Santa Catarina, Palhoça.

Background: Deep infiltrating colorectal endometriosis may severely affect the quality of life and fertility of patients. Although segmental resection is a therapeutic option that provides positive outcomes in the management of symptoms, its functional effects are still unproven.

Aim: Assess the late impact of the laparoscopic approach in treating deep infiltrating endometriosis with segmental colorectal resection. Read More

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December 2018

Local injection of tissue-plasminogen activator using a pulse spray catheter as a treatment option for proximal deep vein thrombosis: A case report.

J Cardiol Cases 2014 Nov 27;10(5):163-166. Epub 2014 Jun 27.

Showa University Northern Yokohama Hospital, Division of Cardiology and Cardiac Catheterization Laboratories, Yokohama, Japan.

A 24-year-old woman was admitted to our hospital with the diagnosis of pulmonary thromboembolism (PTE) and left common iliac vein thrombosis. She had used low-dose contraceptive pill for dysmenorrhea. Otherwise, her laboratory data did not show any other thrombotic risk factors. Read More

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November 2014
1 Read

Increased mast cells in endocervical smears of women with dysmenorrhea.

Cytojournal 2018 12;15:27. Epub 2018 Nov 12.

Address: Department of Obstetrics and Gynecology, Shiga University of Medical Science, Seta, Otsu, Shiga, Japan.

Background: Mast cells are observed in peritoneal endometriosis which causes dysmenorrhea. However, there is no report about the relationship between endocervical mast cells and dysmenorrhea. The aim of this study is to evaluate the relationship using endocervical smears. Read More

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November 2018

Five-Year Contraceptive Efficacy and Safety of a Levonorgestrel 52-mg Intrauterine System.

Obstet Gynecol 2018 Dec 4. Epub 2018 Dec 4.

Department of Obstetrics and Gynecology, University of Colorado, Aurora, Colorado; the Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, Utah; the Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Magee-Womens Research Institute, Pittsburgh, Pennsylvania; the Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk, Virginia; Medicines360, San Francisco, California; and the Department of Obstetrics and Gynecology, University of California, Davis, Sacramento, California.

Objective: To assess the 5-year contraceptive efficacy and safety of a levonorgestrel (LNG) 52-mg intrauterine system (IUS) from an ongoing 10-year phase 3 contraceptive trial.

Methods: Study investigators enrolled 1,751 nulliparous and parous females aged 16-45 years and desiring contraception to receive a novel LNG 52-mg IUS at 29 centers in the United States, including reproductive health clinics, private offices, and university centers. Participants had scheduled follow-up visits four times during the first year. Read More

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December 2018
3 Reads

Uterine contractility changes in a perfused swine uterus model induced by local anesthetics procaine, lidocaine, and ropivacaine.

PLoS One 2018 6;13(12):e0206053. Epub 2018 Dec 6.

Department of Gynecological Endocrinology and Fertility Disorders, University of Heidelberg, Heidelberg, Germany.

Background: Local anesthetics (LAs) are increasingly used as therapeutics due to their multiple molecular effects. They may be potential agents also in gynecology and reproductive medicine. The objective of this study was to investigate the contractility response of the perfused swine uterus to different concentrations of the LAs procaine, lidocaine, and ropivacaine. Read More

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December 2018
1 Read

An update and systematic review on the treatment of primary dysmenorrhea.

JBRA Assist Reprod 2018 Dec 6. Epub 2018 Dec 6.

Nursing Research Center, Golestan University of Medical Sciences, Gorgan, IR Iran.

Objectives: Primary dysmenorrhea is a painful uterine contraction caused by endometrial laceration. Drug therapies and complementary medicine have been used to treat dysmenorrhea. The aim of this study was to investigate and offer an updated perspective on the treatments for dysmenorrhea. Read More

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December 2018
4 Reads

Risk factors related to the recurrence of endometrioma in patients with long-term postoperative medical therapy.

Ginekol Pol 2018 ;89(11):611-617

Department of Obstetrics and Gynecology, Pusan National University School of Medicine Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.

Objectives: The purpose of this study was to identify clinical risk factors for the recurrence of ovarian endometrioma after ovarian cystectomy in Korean women with long-term postoperative medical therapy.

Material And Methods: A total of 134 patients who were surgically treated for endometriotic cysts at Pusan National University Hospital were included in this retrospective study. All patients received long-term postoperative medical treatment for at least 12 months after the first-line conservative surgery. Read More

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January 2018
1 Read

A case report of traditional Korean medicine treatments on uterine myoma with thyroid cancer.

Integr Med Res 2018 Dec 25;7(4):303-306. Epub 2018 Oct 25.

Department of Korean Medicine Obstetrics & Gynecology, College of Korean Medicine, Dae-jeon University, Daejeon, Republic of Korea.

Uterine myoma is a common benign tumor. When the symptoms are not severe, patients are often suggested to wait for menopause without treatment. If the size becomes too large or the symptoms get worse, the patient will receive surgery or hormone therapy. Read More

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December 2018
1 Read

Case Report: Persistent Genital Arousal Disorder in an Adolescent Woman.

Authors:
Kelly A Curran

J Pediatr Adolesc Gynecol 2018 Dec 1. Epub 2018 Dec 1.

Section of Adolescent Medicine, Department of Pediatrics, University of Oklahoma Health Sciences Center, 1200 Children's Avenue, Suite 12204 Oklahoma City, OK. Electronic address:

Background: After several visits with unrelated complaints, a 16-year-old female disclosed symptoms of unwanted genital arousal and was diagnosed with persistent genital arousal disorder (PGAD).

Case: A 16-year-old female with history of depression, sexual abuse, and dysmenorrhea insistently requested etonogestrel rod removal. At two visits following implant removal, the patient disclosed the reason for her insistence: PGAD symptoms developed after implant insertion, though they worsened with removal. Read More

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December 2018
12 Reads

Mechanism of penehyclidine hydrochloride on a dysmenorrhea rat model.

Drug Dev Res 2018 Dec 3. Epub 2018 Dec 3.

Department of Gynaecology and Obstetrics, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, Sichuan, China.

Primary dysmenorrhea affects the quality of life in young women, particularly school and work performance. This study investigated the mechanisms of penehyclidine hydrochloride (PHC) efficacy on a rat model of primary dysmenorrhea. The model was induced by injecting both estradiol benzoate and oxytocin. Read More

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December 2018
1 Read

The Clinical Anatomy of Endometriosis: A Review.

Cureus 2018 Sep 25;10(9):e3361. Epub 2018 Sep 25.

Neurosurgery, Seattle Science Foundation, Seattle, USA.

Endometriosis is a gynecological disorder identified by the presence of ectopic endometrial tissue outside the uterus. Largely, it affects reproductive-aged women and is a major cause of infertility. Clinical manifestations of endometriosis include dyspareunia, cyclic menstrual pain, chronic pelvic pain, and dyschezia, all of which can affect the patient's quality of life and health severely; therefore, it is paramount that medical treatment is initiated as soon as endometriosis is suspected clinically. Read More

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September 2018
2 Reads

Comparative efficacy and safety of NSAIDs-controlled acupuncture in the treatment of patients with primary dysmenorrhoea: a Bayesian network meta-analysis.

J Int Med Res 2018 Nov 30:300060518800609. Epub 2018 Nov 30.

2 Clinical Medical College of Acupuncture, Moxibustion and Rehabilitation Clinic, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.

Background: Acupuncture and non-steroidal anti-inflammatory drugs (NSAIDs) are used frequently to treat primary dysmenorrhoea. However, it is unclear whether this treatment greatly reduces the risk of primary dysmenorrhoea.

Methods: Eight databases were searched up to January 2018. Read More

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November 2018
2 Reads

Obesity as an effect modifier of the association between menstrual abnormalities and hypertension in young adult women: Results from Project ELEFANT.

PLoS One 2018 28;13(11):e0207929. Epub 2018 Nov 28.

Human Nutrition Research Centre, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.

Background: The menstrual cycle is regulated by reproductive hormones such as estrogen which has been implicated in the pathogenesis of hypertension and is associated with obesity. However, to date there has scant study of hypertension in relation to menstrual characteristics and abnormalities. We hypothesize that adverse menstrual characteristics are associated with an increase the prevalence of hypertension and that this relationship is exacerbated by obesity. Read More

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November 2018

The relationship between smoking and dysmenorrhea: A meta-analysis.

Women Health 2018 Nov 27:1-10. Epub 2018 Nov 27.

c Psychosocial Injuries Research Center , Ilam University of Medical Sciences , Ilam , Iran.

Many studies have investigated the potential association between smoking and dysmenorrhea. However, results from such studies have been inconsistent. In this study, we assessed the association between smoking and dysmenorrhea by meta-analysis. Read More

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November 2018
4 Reads

An integrative urinary metabolomic study of the therapeutic effect of Guizhi Fuling capsule on primary dysmenorrheal rats based H NMR and UPLC-MS.

J Pharm Biomed Anal 2018 Nov 17;164:750-758. Epub 2018 Nov 17.

School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China; School of Pharmacy, Huaihai Institute of Technology, Lianyungang, Jiangsu 222001, China; State Key Laboratory of New-tech For Chinese Medicine Pharmaceutic Process, Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang, Jiangsu 222001, China.

Guizhi Fuling capsule (GFC) was an important traditional Chinese herbal medicine used for the treatment of primary dysmenorrheal (PD). The aim of this study was to evaluate the anti-dysmenorrheal effect of GFC on dysmenorrheal rats induced by oxytocin and to investigate its mechanism of action. An integrative urinary metabolomic study based on H NMR and UPLC-MS was used to investigate the therapeutic effect of GFC on PD rats. Read More

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November 2018
2 Reads

Effect of Menstrugole on primary dysmenorrhea: a randomized clinical trial.

Obstet Gynecol Sci 2018 Nov 11;61(6):684-687. Epub 2018 Oct 11.

Mother and Child Care Research Center, School of Nursing and Midwifery, Hamadan University of Medical Sciences, Hamadan, Iran.

Objective: Primary dysmenorrhea occurs in more than 50% of women of reproductive age. This survey evaluated the effects of Menstrugole on the alleviation of primary dysmenorrhea.

Methods: This study was performed in western Iran between August 15 and December 15, 2017, in female students with primary dysmenorrhea. Read More

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November 2018
6 Reads

Risk of female athlete triad development in Japanese collegiate athletes is related to sport type and competitive level.

Int J Womens Health 2018 30;10:671-687. Epub 2018 Oct 30.

Faculty of Health and Sport Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan,

Introduction: Menstrual dysfunction, musculoskeletal injury, and poor nutrition combine to form the female athlete triad (FAT), which results in serious health consequences for affected athletes. To this point, the risk factors of this phenomenon have not been fully explored in Japanese female college athletes. Additionally, the effect of competitive level on FAT risk factors has also not been reported. Read More

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October 2018
2 Reads

Clinical comparison of mifepristone and gestrinone for laparoscopic endometriosis.

Pak J Pharm Sci 2018 Sep;31(5(Special)):2197-2201

Department of Centerfor Reproductive Medicine, The Affiliated Yantai Yuhuangding Hospital of Medical College, Qingdao University, Yantai, China.

Endometriosis is a common disease among women of childbearing age, and it is the main cause of dysmenorrhea and infertility. This article analyzes the efficacy of mifepristone and gestrinone in the treatment of endometriosis. The results showed that the recurrence rate of mifepristone group and gestrinone group were 8. Read More

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September 2018
2 Reads

ACOG Committee Opinion No. 760: Dysmenorrhea and Endometriosis in the Adolescent.

Authors:

Obstet Gynecol 2018 Dec;132(6):e249-e258

Dysmenorrhea, or menstrual pain, is the most common menstrual symptom among adolescent girls and young women. Most adolescents experiencing dysmenorrhea have primary dysmenorrhea, defined as painful menstruation in the absence of pelvic pathology. When the patient's history suggests primary dysmenorrhea, empiric treatment should be initiated. Read More

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December 2018
7 Reads

ACOG Committee Opinion No. 760 Summary: Dysmenorrhea and Endometriosis in the Adolescent.

Authors:

Obstet Gynecol 2018 Dec;132(6):1517-1518

Dysmenorrhea, or menstrual pain, is the most common menstrual symptom among adolescent girls and young women. Most adolescents experiencing dysmenorrhea have primary dysmenorrhea, defined as painful menstruation in the absence of pelvic pathology. When the patient's history suggests primary dysmenorrhea, empiric treatment should be initiated. Read More

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December 2018
6 Reads

[Pneumothorax catamenial: results of 18 cases operas].

Pan Afr Med J 2018 25;30:168. Epub 2018 Jun 25.

Service de Chirurgie Thoracique, Institut de Cardiologie d'Abidjan, Abidjan, Côte d'Ivoire.

This study aims to propose a therapeutic approach for catamenial pneumothorax based on outcomes reported in 18 cases. We conducted a retrospective study of 18 female elderly patients with an average age of 32.2 years who had undergone surgery for right (16 cases) and bilateral catamenial pneumothorax (2 cases) from January 1994 to December 2016. Read More

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December 2018
1 Read

Late morbidity in cesarean section scar syndrome.

Ceska Gynekol Fall 2018;83(4):300-306

Objective: To summarize recent knowledge on ethiology, diagnostic management and treatment possibilities of cesarean section scar syndrome (isthmocoele).

Design: Review article.

Setting: Department of Gynaecology and Obstetrics, Faculty Hospital and Palacky University, Olomouc; Department of Gynaecology and Obstetrics, Vítkovická nemocnice, Ostrava-Vítkovice. Read More

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November 2018
3 Reads

A phase 2b multicenter, randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of vaginal rings containing nomegestrol acetate or etonogestrel and 17β-estradiol in the treatment of women with primary dysmenorrhea.

Contraception 2018 Nov 12. Epub 2018 Nov 12.

Reprovision Clinical Consultancy, Beethovengaarde 111, 5344, CE, Oss, The Netherlands. Electronic address:

Objective: To evaluate the effect of investigational vaginal rings containing nomegestrol acetate (NOMAC) plus 17β-estradiol (E2) or etonogestrel (ENG) plus E2 in women with moderate to severe primary dysmenorrhea.

Study Design: This was a Phase 2b randomized, placebo-controlled, multicenter, double-blind study. We randomized participants to one of five treatment groups: four hormonal rings and one placebo ring. Read More

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November 2018

Preconception dysmenorrhea as a risk factor for psychological distress in pregnancy: The Japan Environment and Children's Study.

J Affect Disord 2018 Nov 5;245:475-483. Epub 2018 Nov 5.

Division of Public Health, Hygiene and Epidemiology, Tohoku Medical and Pharmaceutical University Faculty of Medicine. 1-15-1 Fukumuro, Miyagino-ku, Sendai, Miyagi 983-8536, Japan; Tohoku Medical Megabank Organization, Tohoku University. 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8573, Japan. Electronic address:

Background: Dysmenorrhea influences emotional distress as well as physical suffering in young non-pregnant women. The aim of this study was to assess the potential association between preconception dysmenorrhea and the development of psychological distress during pregnancy.

Methods: This study was a part of the Japan Environment and Children's Study (JECS), a nationwide birth cohort study conducted between 2011 and 2014 in Japan. Read More

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November 2018
6 Reads

Bilateral salpingectomy versus bilateral partial salpingectomy during cesarean delivery.

Int J Womens Health 2018 23;10:649-653. Epub 2018 Oct 23.

Department of Obstetrics and Gynecology, University of Tennessee Health Science Center, Memphis, TN, USA,

Objective: To compare surgical outcomes in patients undergoing bilateral salpingectomy (salpingectomy group) with those who had partial salpingectomy (partial salpingectomy group) during cesarean delivery.

Materials And Methods: A chart review from July 2015 to November 2016 was performed. We included women who had sterilization during cesarean delivery. Read More

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October 2018
12 Reads

Aromatherapy for Managing Pain in Primary Dysmenorrhea: A Systematic Review of Randomized Placebo-Controlled Trials.

J Clin Med 2018 Nov 10;7(11). Epub 2018 Nov 10.

Department of Nursing, Chodang University, Muan-gun 58530, Korea.

Aromatherapy, the therapeutic use of essential oils, is often used to reduce pain in primary dysmenorrhea. Eleven databases, including four English (PubMed, AMED, EMBASE, and the Cochrane Library) and seven Korean medical databases, were searched from inception through August 2018 without restrictions on publication language. Randomized controlled trials (RCTs) testing aromatherapy for pain reduction in primary dysmenorrhea were considered. Read More

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November 2018
7 Reads

Mesenteric vascular and nerve sparing surgery in laparoscopic segmental intestinal resection for deep infiltrating endometriosis.

Eur J Obstet Gynecol Reprod Biol 2018 Dec 1;231:214-219. Epub 2018 Nov 1.

Department of Obstetrics and Gynecology, AOUI Verona, University of Verona, Verona, Italy.

Objective(s): To investigate Mesenteric vascular and nerve Sparing Surgery (MSS) as surgical laparoscopic technique to perform segmental intestinal resection for deep infiltrating endometriosis (DIE).

Study Design: Prospective cohort study between January 2013 and December 2016. Consecutive patients with suspected intestinal DIE underwent clinical and imaging evaluation to confirm intestinal involvement. Read More

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December 2018
4 Reads
1.630 Impact Factor

[Additional non-contraceptive effects of contraception: CNGOF Contraception Guidelines].

Gynecol Obstet Fertil Senol 2018 Nov 7. Epub 2018 Nov 7.

Service de gynécologie-obstétrique, CHRU de Nancy, 10, avenue du Dr-Heydenreich, 54035 Nancy, France. Electronic address:

Hormonal and intrauterine contraceptive methods provide women with highly efficient protection against undesired pregnancy. Additional non-contraceptive effects are now well documented. Combined hormonal contraceptives use, either through the oral transdermal and vaginal route, allow a reduction in menorrhagia, dysmenorrhea, functional ovarian cysts, benign breast and uterine disease, endometriosis-related pain and recurrence. Read More

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November 2018
4 Reads

Pelvic pain in young girls: not only dysmenorrhoea!

BMJ Case Rep 2018 Nov 8;2018. Epub 2018 Nov 8.

Gynecology and Obstetrics Department, Hospital de Braga, Braga, Portugal.

Imperforate hymen is the most frequent cause of haematocolpos, although it is a rare malformation (1:2000). We present two cases of young girls with cyclic abdominal pain and urinary symptoms. At gynaecological examination, they all presented imperforate hymen and ultrasound revealed significant vaginal distension. Read More

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November 2018
10 Reads

"Complementary Medicine": Complementary and alternative health approaches in pediatric and adolescent gynecology.

J Pediatr Adolesc Gynecol 2018 Nov 3. Epub 2018 Nov 3.

Division of Adolescent and Transition Medicine, Child Life & Integrative Care, Cincinnati Children's Hospital Medical Center.

Complementary and alternative health care approaches are prevalent in the patients and families served by practitioners in pediatric and adolescent gynecology. This paper addresses gaps in knowledge, including new terminology, prevalence of use, rates of and reasons behind nondisclosure, and potential interactions of herbal products with prescribed medication. It closes with practical complementary health approaches to the adolescent with dysmenorrhea. Read More

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November 2018
6 Reads

The effect of Cinnamon on primary dysmenorrhea: A randomized, double-blind clinical trial.

Complement Ther Clin Pract 2018 Nov 15;33:56-60. Epub 2018 Aug 15.

Department of Midwifery & Reproductive Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: Primary dysmenorrhea is a cyclic cramp in pelvic which interferes with daily activity. This study determined the effect of Cinnamon on relieving dysmenorrhea.

Methods: This is a randomized, double-blind clinical trial. Read More

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November 2018
5 Reads

Short-term effects of connective tissue manipulation in women with primary dysmenorrhea: A randomized controlled trial.

Complement Ther Clin Pract 2018 Nov 21;33:1-6. Epub 2018 Jul 21.

Hacettepe University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, 06100, Samanpazarı, Ankara, Turkey. Electronic address:

Aim: To evaluate the short-term effectiveness of connective tissue manipulation (CTM) for relieving menstrual pain and symptoms in primary dysmenorrhea (PD).

Methods: Forty-four women with PD were randomly assigned to treatment (n = 21) or control group (n = 23). While the control group was given only advising, the treatment group additionally received CTM. Read More

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November 2018
4 Reads

A sonographic classification of adenomyosis: interobserver reproducibility in the evaluation of type and degree of the myometrial involvement.

Fertil Steril 2018 Nov;110(6):1154-1161.e3

Department of Biomedicine and Prevention Obstetrics and Gynecological Clinic, University of Rome "Tor Vergata", Rome, Italy. Electronic address:

Objective: To study the interobserver reproducibility of our new ultrasonographic mapping system to define the type and extension of uterine adenomyosis.

Design: Interobserver study involving two observers with different medical backgrounds and gynecological ultrasound experience.

Setting: University hospital. Read More

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November 2018
8 Reads

Control of endometriosis-associated pain with etonogestrel-releasing contraceptive implant and 52-mg levonorgestrel-releasing intrauterine system: randomized clinical trial.

Fertil Steril 2018 Nov;110(6):1129-1136

Department of Obstetrics and Gynecology, Faculty of Medical Sciences, University of Campinas, Campinas, São Paolo, Brazil. Electronic address:

Objective: To assess the efficacy of an etonogestrel (ENG)-releasing contraceptive implant or the 52-mg levonorgestrel-releasing intrauterine system (LNG-IUS) in the control of endometriosis-associated pelvic pain.

Design: Noninferiority randomized clinical trial in which women with endometriosis were assigned to use an ENG implant (experimental treatment) or an LNG-IUS (active comparator). Monthly follow-up visits were conducted up to 6 months. Read More

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November 2018
3 Reads

Diagnosis and Management of an Adenomatoid Uterine Tumor: Ultrasound, Magnetic Resonance Imaging, Surgical Appearance, and Pathology Correlation.

Biores Open Access 2018 26;7(1):159-164. Epub 2018 Oct 26.

Department of Obstetrics and Gynecology and Texas Tech University Health Sciences Center, Lubbock, Texas.

Adenomatoid uterine tumors are rare, and their appearance on medical imaging modalities is not well established. We present a case of an adenomatoid uterine tumor reviewing a unique sonographic presentation, magnetic resonance imaging (MRI), gross surgical appearance of the tumor, and microscopic pathology images. A 29-year-old gravida 0 Caucasian woman presented with dysmenorrhea, menorrhagia, and desire to conceive. Read More

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October 2018
2 Reads

Heat therapy for primary dysmenorrhea: A systematic review and meta-analysis of its effects on pain relief and quality of life.

Sci Rep 2018 Nov 2;8(1):16252. Epub 2018 Nov 2.

Department of Pediatrics of Korean Medicine, Kyung Hee University Korean Medicine Hospital, Kyung Hee University Medical Center, 23 Kyungheedae-ro, Dongdaemun-gu, 02447, Seoul, Republic of Korea.

Primary dysmenorrhea, which is menstrual pain without pelvic pathology, is the most common gynecologic condition in women. Heat therapy has been used as a treatment. We assessed the evidence on heat therapy as a treatment for primary dysmenorrhea. Read More

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November 2018
3 Reads

Correlation of LOX‑5 and COX‑2 expression with inflammatory pathology and clinical features of adenomyosis.

Mol Med Rep 2018 Nov 1. Epub 2018 Nov 1.

Department of Gynecology and Obstetrics, Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, P.R. China.

Adenomyosis is a common benign disease of women of childbearing age. The typical clinical features are prolonged menstruation, menorrhagia and ingravescent dysmenorrhea. In the present study, the severity of dysmenorrhea was assessed using the visual analogue scale system as follows: 0, No pain; 1‑3, minimal pain; 4‑6, moderate pain; and 7‑10, severe pain. Read More

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November 2018
3 Reads

RhoA/ROCK/ARHGAP26 signaling in the eutopic and ectopic endometrium is involved in clinical characteristics of adenomyosis.

J Int Med Res 2018 Nov 2:300060518789038. Epub 2018 Nov 2.

3 Department of Gynecology and Obstetrics, Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.

Objective: This study aimed to investigate RhoA, RhoA-associated coiled-coil containing protein kinase (ROCK) 1, ROCK2, and Rho GTPase-activating protein 26 (ARHGAP26) expression in the eutopic endometrium (EU) and ectopic endometrium (EC), and examine their relationships with the clinical characteristics of adenomyosis.

Methods: Twenty patients with adenomyosis who underwent laparoscopy were recruited. Protein and mRNA expression of RhoA, ROCK1, ROCK2, and ARHGAP26 in EU and EC of patients with adenomyosis and in control endometrium without adenomyosis (CE) was detected. Read More

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November 2018
2 Reads

Extrapelvic endometriosis in abdominal wall scar and PPAR gamma expression: A case report.

Int J Surg Case Rep 2018 Oct 24;53:66-69. Epub 2018 Oct 24.

Division of Reproductive Endocrinology and Infertility, Department of Obstetric and Gynecology, Faculty of Medicine, Universitas Indonesia, Dr.Cipto Mangunkusumo General Hospital, Jakarta, Indonesia.

Introduction: Endometriosis is a frequent gynecological disorder. Its findings on the abdominal wall are rare cases, usually reported with a history of former surgery. The activation of PPARy expression could be one of alternative non-hormonal treatment for endometriosis. Read More

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October 2018
2 Reads

Naturopathic Medicine for the Management of Endometriosis, Dysmenorrhea, and Menorrhagia: A Content Analysis.

J Altern Complement Med 2018 Oct 31. Epub 2018 Oct 31.

1 Australian Research Centre in Complementary and Integrative Medicine, Faculty of Health, University of Technology Sydney , Ultimo, New South Wales, Australia .

Objectives: To explore the recommendations of naturopathic medicine for the management of endometriosis, dysmenorrhea, and menorrhagia, drawing on traditional and contemporary sources.

Design: Content analysis.

Setting: Australia, Canada, and the United States of America (USA). Read More

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October 2018
2 Reads

Preliminary insights on the relation between endometriosis, pelvic pain, and employment.

Gynecol Obstet Invest 2018 Oct 31:1-6. Epub 2018 Oct 31.

Department of Clinical Sciences and Community Health, Università degli Studi, and Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Aims: The economic burden of endometriosis and pelvic pain involves direct and indirect healthcare costs due to work loss and decreased productivity. However, the relation between endometriosis, pelvic pain, and employment remains underinvestigated. This study aimed at providing preliminary insights into this topic. Read More

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October 2018
3 Reads

Whole brain structural MRI based classification of primary dysmenorrhea in pain-free phase: a machine learning study.

Pain 2018 Oct 29. Epub 2018 Oct 29.

Center for Brain Imaging, School of Life Science and Technology, Xidian University, Xi'an 710126, Peoples R China.

To develop a machine learning model to investigate the discriminative power of whole-brain gray matter (GM) images derived from primary dysmenorrhea (PDM) women and healthy controls (HC) during the pain-free phase, and further evaluate the predictive ability of contributing features in predicting the variance in menstrual pain intensity. Sixty PDM patients and 54 matched female HC were recruited from the local university. All participants underwent the head and pelvic MRI scans to calculate GM volume and myometrium apparent diffusion coefficient (ADC) during their periovulatory phase. Read More

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October 2018
1 Read

Predisposing factors for predicting the therapeutic response of adenomyosis after uterine artery embolization: serum CA125 levels and accompanying endometriosis.

Diagn Interv Radiol 2018 Nov;24(6):364-371

Department of Radiology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Purpose: We aimed to identify predisposing factors that could help predict the therapeutic response of adenomyosis after uterine artery embolization (UAE).

Methods: This was a retrospective, single-center study of patients admitted to the hospital for adenomyosis between 2013 and 2015. Sixty-eight patients with adenomyosis who underwent UAE with tris-acryl gelatin microspheres were divided into two groups based on their therapeutic response (complete or incomplete necrosis of lesions), and pre- and postprocedural pelvic magnetic resonance imaging (MRI) data. Read More

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November 2018
6 Reads

Assessment of biomarkers in women with endometriosis-associated pain using the ENG contraceptive implant or the 52 mg LNG-IUS: a non-inferiority randomised clinical trial.

Eur J Contracept Reprod Health Care 2018 Oct 29;23(5):344-350. Epub 2018 Oct 29.

a Department of Obstetrics and Gynaecology , University of Campinas Medical School , Campinas , Brazil.

Objective: The aim of the study was to assess the serum levels of the following biomarkers in women with endometriosis-associated pelvic pain before and after six months of using the etonogestrel (ENG) contraceptive implant or the 52 mg levonorgestrel-releasing intrauterine system (LNG-IUS): cancer antigen (CA)-125, cluster of differentiation (CD) 23 and endometrial nerve fibre density.

Methods: The study was conducted at the Department of Obstetrics and Gynaecology, University of Campinas Medical School, Brazil. A total of 103 women with endometriosis-associated pain diagnosed by surgery, transvaginal ultrasound and/or magnetic resonance imaging were included. Read More

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October 2018
11 Reads

Efficacy of a Herbal Formulation Based on Foeniculum Vulgare in Oligo/Amenorrhea: A Randomized Clinical Trial.

Curr Drug Discov Technol 2018 Oct 29. Epub 2018 Oct 29.

Department of Persian Medicine, School of Persian and Complementary Medicine, Mashhad University of Medical Sciences, Mashhad. Iran.

Background: The aim of this study was to evaluate the efficacy of the herbal tea based on Foeniculum vulgare, on inducing regular bleeding in women with oligomenorrhea and secondary amenorrhea(oligo/amenorrhea).

Methods: Forty women aged 18- 40 with oligo/amenorrhea were enrolled in this randomized controlled clinical trial and were allocated to two groups equally. The women in the first group were treated by Fomentex (Foeniculum vulgare / Mentha longifolia / Vitex agnus-castus) herbal tea 11. Read More

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October 2018
5 Reads

[Degree of fibrosis of adenomyotic myometrium and its relationship with dysmenorrhea].

Zhonghua Fu Chan Ke Za Zhi 2018 Oct;53(10):689-693

Gynecological Minimally Invasive Center, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100006, China.

To investigate degrees of fibrosis of adenomyosis (AM) myometrium and explore its relationship with dysmenorrhea. Thirty AM patients who had hysterectomy from July, 2015 to December, 2016 in Beijing Obstetrics and Gynecology Hospital were selected as AM group; 28 cases of hysterectomy due to cervical lesions (none AM) were selected as control group. The area ratio of collagen fiber in the two groups was analysed by modified Masson stain, and the expression of collagen type Ⅰprotein in the two groups was analysed by immunohistochemical method. Read More

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October 2018
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Association of Pelvic Inflammatory Disease with Risk of Endometriosis: A Nationwide Cohort Study Involving 141,460 Individuals.

J Clin Med 2018 Oct 24;7(11). Epub 2018 Oct 24.

School of Chinese Medicine, China Medical University, Taichung 40402, Taiwan.

Endometriosis occurs when endometrial tissue exists outside the uterine cavity. The presence of ectopic endometrial tissue and resultant inflammation cause serious symptoms, including chronic pelvic pain, dysmenorrhea, dyspareunia, and infertility. Pelvic inflammatory disease is caused by the ascension of pathogenic bacteria from the vagina to the uterus, Fallopian tubes, and ovaries. Read More

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October 2018
5 Reads