309,920 results match your criteria Dynamic Medicine [Journal]


[Introduction: The city of Villeurbanne has made the political choice to reduce social inequalities in health (SIH). The Public Health Department wanted to assess the health impact in the context of this project. The main objective was to analyse the links between urban development and health in order to identify the impact of the urban project on health and to make recommendations to reduce physical inactivity of children. Attention was focused on a neighbourhood of 6,000 inhabitants in the process of urban renewal. A high rate of adults on antidiabetic treatment was observed in this relatively deprived neighbourhood. School medicine also noted a high proportion of overweight children in schools in the neighbourhood, higher than in all schools of the city. The objective of this HIA was therefore to identify the impact of the renovation project on children’s mobility and to make recommendations in order to combat their physical inactivity by encouraging spontaneous physical activity.Methods: The selected determinants were grouped into four categories: outdoor environment, use of open spaces, adapted sports facilities/equipment, roads. The evaluation was based on analysis of urban planning documents, environmental analysis reports, ad hoc surveys, individual interviews with the various partners and target actors. A bibliographic review confirmed the positive or negative impacts of various aspects of the project on health.Results: Although some aspects of the project had a positive impact on the health of the inhabitants, others have a negative impact on children’s mobility, well-being and social capital. About 30 recommendations were proposed and prioritized according to their political support and their technical, economic and temporal feasibility.Discussion].

Sante Publique 2018 Sep;S2(HS2):63-67

Introduction: The city of Villeurbanne has made the political choice to reduce social inequalities in health (SIH). The Public Health Department wanted to assess the health impact in the context of this project. The main objective was to analyse the links between urban development and health in order to identify the impact of the urban project on health and to make recommendations to reduce physical inactivity of children. Read More

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September 2018

Statistical Network Inference for Time-Varying Molecular Data with Dynamic Bayesian Networks.

Methods Mol Biol 2019 ;1883:25-48

German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.

In this chapter, we review the problem of network inference from time-course data, focusing on a class of graphical models known as dynamic Bayesian networks (DBNs). We discuss the relationship of DBNs to models based on ordinary differential equations, and consider extensions to nonlinear time dynamics. We provide an introduction to time-varying DBN models, which allow for changes to the network structure and parameters over time. Read More

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January 2019

The Role of Vitamins and Minerals in Hair Loss: A Review.

Dermatol Ther (Heidelb) 2018 Dec 13. Epub 2018 Dec 13.

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1475 NW 12th Ave. Suite 2175, Miami, FL, 33136, USA.

People commonly inquire about vitamin and mineral supplementation and diet as a means to prevent or manage dermatological diseases and, in particular, hair loss. Answering these queries is frequently challenging, given the enormous and conflicting evidence that exists on this subject. There are several reasons to suspect a role for micronutrients in non-scarring alopecia. Read More

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December 2018
1 Read

Leaf litter species identity influences biochemical composition of ectomycorrhizal fungi.

Mycorrhiza 2018 Dec 13. Epub 2018 Dec 13.

Forest Botany and Tree Physiology, University of Goettingen, Buesgenweg 2, 37077, Goettingen, Germany.

In forest ecosystems, ectomycorrhizal (ECM) fungi are important for plant growth and soil biogeochemical processes. The biochemical composition of ECM mycelium is an important fungal effect trait with consequences for its decomposition rate, and consequently on soil carbon pools and plant nutrition. Although the link between ECM fungi and leaf litter-released nutrients is well known, the response of ECM fungal biochemical composition to different leaf litter species remains poorly understood. Read More

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December 2018

Effects of Flywheel Training on Strength-Related Variables: a Meta-analysis.

Sports Med Open 2018 Dec 13;4(1):55. Epub 2018 Dec 13.

Åstrand Laboratory of Work Physiology, The Swedish School of Sport and Health Sciences, Stockholm, Sweden.

Background: Strength and power development are abilities important for athletic performance in many sports. Generally, resistance training based on gravity is used to improve these qualities. Flywheel training instead utilizes kinetic energy transferred to a flywheel. Read More

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December 2018

Pumpless platform for high-throughput dynamic multicellular culture and chemosensitivity evaluation.

Lab Chip 2018 Dec 14. Epub 2018 Dec 14.

Department of Chemical Engineering and Materials Science, Stevens Institute of Technology, 1 Castle Point on Hudson, Hoboken, New Jersey 07030, USA.

We report here a novel pumpless, 96-well plate-based platform for high-throughput dynamic multicellular culture and chemosensitivity evaluation. A gravity-driven flow strategy was developed to generate and sustain the flow rate of culture medium within 10% in the platform's 20 culture chambers. The ability of the platform to generate and sustain the medium flow was demonstrated by computational simulation, flow visualization, and ascertaining the previously known effect of flow-induced shear stress on the stimulated osteogenic differentiation of osteoblasts. Read More

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December 2018

Influence spreading model used to analyse social networks and detect sub-communities.

Authors:
Vesa Kuikka

Comput Soc Netw 2018 29;5(1):12. Epub 2018 Nov 29.

Finnish Defence Research Agency, PO BOX 10, Tykkikentäntie 1, 11311 Riihimäki, Finland.

A dynamic influence spreading model is presented for computing network centrality and betweenness measures. Network topology, and possible directed connections and unequal weights of nodes and links, are essential features of the model. The same influence spreading model is used for community detection in social networks and for analysis of network structures. Read More

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November 2018

Layered calcium phenylphosphonate: a hybrid material for a new generation of nanofillers.

Beilstein J Nanotechnol 2018 20;9:2906-2915. Epub 2018 Nov 20.

SYNPO, akciová společnost, S. K. Neumanna 1316, 532 07 Pardubice, Czech Republic.

The use of nanosheets of layered calcium phenylphosphonate as a filler in a polymeric matrix was investigated. Layered calcium phenylphosphonate (CaPhP), with chemical formula CaCHPO∙2HO, is a hybrid organic-inorganic material that exhibits a hydrophobic character due to the presence of phenyl groups on the surface of the layers. In this paper, various CaPhP synthesis methods were studied with the aim of obtaining a product most suitable for its subsequent exfoliation. Read More

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November 2018
1 Read

Large-scale loyalty card data in health research.

Digit Health 2018 Jan-Dec;4:2055207618816898. Epub 2018 Nov 29.

Department of Food and Nutrition, University of Helsinki, Helsinki, Finland.

Objective: To study the characteristics of large-scale loyalty card data obtained in Finland, and to evaluate their potential and challenges in health research.

Methods: We contacted the holders of a certain loyalty card living in a specific region in Finland via email, and requested their electronic informed consent to obtain their basic background characteristics and grocery expenditure data from 2016 for health research purposes. Non-participation and the characteristics and expenditure of the participants were mainly analysed using summary statistics and figures. Read More

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November 2018
1 Read

Decreased levels of regulatory B cells in patients with acute pancreatitis: association with the severity of the disease.

Oncotarget 2018 Nov 3;9(90):36067-36082. Epub 2018 Jan 3.

Department of Intensive Care Unit, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, 310004, China.

Early stratification of the severity of acute pancreatitis (AP) is clinically important. Regulatory B cells have been found to be associated with disease activity of autoimmune diseases. However, the role of Regulatory B cells in AP remains unknown. Read More

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November 2018

Transaminase-Catalyzed Racemization with Potential for Dynamic Kinetic Resolutions.

ChemCatChem 2018 Nov 11;10(21):5012-5018. Epub 2018 Oct 11.

Department of Industrial Biotechnology KTH Royal Institute of Technology AlbaNova University Center Stockholm SE-106 91 Sweden.

Dynamic kinetic resolution (DKR) reactions in which a stereoselective enzyme and a racemization step are coupled in one pot would represent powerful tools for the production of enantiopure amines through enantioconvergence of racemates. The exploitation of DKR strategies is currently hampered by the lack of effective, enzyme-compatible and scalable racemization strategies for amines. In the present work, the proof of concept of a fully biocatalytic method for amine racemization is presented. Read More

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November 2018
1 Read

Dynamic instability of the acromioclavicular joint: A new classification for acute AC joint separation.

Obere Extrem 2018 28;13(4):279-285. Epub 2018 Jun 28.

2Center for Musculoskeletal Surgery, Campus Virchow, Charité-Universitaetsmedizin, Berlin, Germany.

Background: Acute acromioclavicular (AC) dislocation is classified according to Rockwood (RW). Although of clinical relevance, dynamic horizontal translation (DHT) is not listed in this classification or in frequently used clinical evaluation tools. The aim of this study was (a) to evaluate vertical and horizontal AC joint instabilities and assess their combined occurrence and clinical appearance in a consecutive group of patients, as well as (b) to develop a new classification of acute AC joint dislocation. Read More

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Dynamic changes and diagnostic and prognostic significance of serum PCT, hs-CRP and s-100 protein in central nervous system infection.

Exp Ther Med 2018 Dec 16;16(6):5156-5160. Epub 2018 Oct 16.

Inspection Department, People's Hospital of Rizhao, Rizhao, Shandong 276800, P.R. China.

The aim of the study was to analyze the dynamic changes and diagnostic and prognostic significance of serum procalcitonin (PCT), high-sensitivity C-reactive protein (hs-CRP) and s-100 protein in central nervous system infection. A total of 110 patients diagnosed with central nervous system infection in Department of Neurology in the People's Hospital of Rizhao from January 2014 to January 2016 were selected and retrospectively analyzed; they were divided into the bacterium (n=70) and virus (n=40) groups. Another 45 normal subjects were selected as the control group. Read More

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December 2018

Meaningful Memory? Eighteen-Month-Olds Only Remember Cartoons With a Meaningful Storyline.

Front Psychol 2018 28;9:2388. Epub 2018 Nov 28.

Department of Psychology and Behavioral Sciences, Center on Autobiographical Memory Research, Aarhus University, Aarhus, Denmark.

In two studies we investigated the importance of a storyline for remembering cartoons across a delay of 2 weeks in 18-month-old infants by means of the visual paired-comparison (VPC) paradigm. In Study 1 seventy-one 18-month-olds were tested using similar cartoons as in a recent study from our lab while varying the richness of the storyline information. In a VPC task half of the infants watched uncompromised versions of the cartoons used in the recent study (Storyline Condition), whereas the other half watched Pixelized versions of the cartoons (number of pixels reduced by 98% covering up the narrative, but leaving perceptual details, e. Read More

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November 2018
1 Read

Pupillary Measures of the Cognitive Effort in Auditory Novel Word Processing and Short-Term Retention.

Front Psychol 2018 27;9:2248. Epub 2018 Nov 27.

Department of Psychology, Universidad Complutense de Madrid, Madrid, Spain.

The use of the task-evoked pupillary responses (TEPRs) methodology is emerging in the psycholinguistics literature, as a sensitive, reliable and dynamic psychophysiological measure of the cognitive effort produced by various aspects of language processing. This preliminary study aimed to assess the functionality and effectiveness of a TEPRs design for measuring the cognitive effort required for the processing and spontaneous (non-explicitly prompted) short-term retention of novel phonological forms presented auditorily. Twenty-four young adult participants (aged 19-28 years, = 20. Read More

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November 2018
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Genetic and Environmental Influences on the Affective Regulation Network: A Prospective Experience Sampling Analysis.

Front Psychiatry 2018 28;9:602. Epub 2018 Nov 28.

Department of Psychiatry and Psychology, Maastricht University Medical Centre, Maastricht, Netherlands.

The study of networks of affective mental states that play a role in psychopathology may help model the influence of genetic and environmental risks. The aim of the present paper was to examine networks of affective mental states (AMS: "cheerful," "insecure," "relaxed," "anxious," "irritated," and "down") over time, stratified by genetic liability for psychopathology and exposure to environmental risk, using momentary assessment technology. Momentary AMS, collected using the experience sampling method (ESM) as well as childhood trauma and genetic liability (based on the level of shared genes and psychopathology in the co-twin) were collected in a population-based sample of female-female twin pairs and sisters (585 individuals). Read More

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November 2018

Gene Regulatory Network Modeling of Macrophage Differentiation Corroborates the Continuum Hypothesis of Polarization States.

Front Physiol 2018 27;9:1659. Epub 2018 Nov 27.

Institute for Applied Computing, National Research Council of Italy, Rome, Italy.

Macrophages derived from monocyte precursors undergo specific polarization processes which are influenced by the local tissue environment: classically activated (M1) macrophages, with a pro-inflammatory activity and a role of effector cells in Th1 cellular immune responses, and alternatively activated (M2) macrophages, with anti-inflammatory functions and involved in immunosuppression and tissue repair. At least three different subsets of M2 macrophages, namely, M2a, M2b, and M2c, are characterized in the literature based on their eliciting signals. The activation and polarization of macrophages is achieved through many, often intertwined, signaling pathways. Read More

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November 2018

A Cell Atlas for the Mouse Brain.

Front Neuroinform 2018 28;12:84. Epub 2018 Nov 28.

Blue Brain Project, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

Despite vast numbers of studies of stained cells in the mouse brain, no current brain atlas provides region-by-region neuron counts. In fact, neuron numbers are only available for about 4% of brain of regions and estimates often vary by as much as 3-fold. Here we provide a first 3D cell atlas for the whole mouse brain, showing cell positions constructed algorithmically from whole brain Nissl and gene expression stains, and compared against values from the literature. Read More

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November 2018
1 Read

Dynamic microtubules drive fibroblast spreading.

Biol Open 2018 Dec 13;7(12). Epub 2018 Dec 13.

Department of Electron Microscopy, A.N. Belozersky Institute of Physico-Chemical Biology, M.V. Lomonosov State University, 1-40 Leninskie Gory, Moscow 119991, Russia

When cells with a mesenchymal type of motility come into contact with an adhesive substrate they adhere and start spreading by the formation of lamellipodia. Using a label-free approach and virtual synchronization approach we analyzed spreading in fibroblasts and cancer cells. In all cell lines spreading is a non-linear process undergoing isotropic or anisotropic modes with first fast (5-20 min) and then slow (30-120 min) phases. Read More

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December 2018

Allosteres to Regulate Neurotransmitter Sulfonation.

J Biol Chem 2018 Dec 13. Epub 2018 Dec 13.

Microbiology & Immunology, The Albert Einstein College of Medicine, United States.

Catecholamine neurotransmitter levels in the synapses of the brain shape human disposition - cognitive flexibility, aggression, depression, reward seeking… - and manipulating these levels is a major objective of the pharmaceutical industry. Certain neurotransmitters are extensively sulfonated and inactivated by human sulfotransferase 1A3 (SULT1A3). To our knowledge, sulfonation as therapeutic means of regulating transmitter activity has not been explored. Read More

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December 2018
2 Reads

Long noncoding RNAs of single hematopoietic stem and progenitor cells in healthy and dysplastic human bone marrow.

Haematologica 2018 Dec 13. Epub 2018 Dec 13.

NHLBI/NIH.

Long noncoding RNAs (lncRNAs), which are regulators of cell differentiation and development. The lncRNA transcriptome in human hematopoietic stem and progenitor cells is not comprehensively defined. We investigated lncRNAs in 979 human bone marrow-derived CD34+ cells by single cell RNA sequencing followed by de novo transcriptome reconstruction. Read More

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December 2018

Multilayer network switching rate predicts brain performance.

Proc Natl Acad Sci U S A 2018 Dec 13. Epub 2018 Dec 13.

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, VIC 3010, Australia.

Large-scale brain dynamics are characterized by repeating spatiotemporal connectivity patterns that reflect a range of putative different brain states that underlie the dynamic repertoire of brain functions. The role of transition between brain networks is poorly understood, and whether switching between these states is important for behavior has been little studied. Our aim was to model switching between functional brain networks using multilayer network methods and test for associations between model parameters and behavioral measures. Read More

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December 2018
1 Read

A Golgi-released subpopulation of the trans-Golgi network mediates protein secretion in Arabidopsis.

Plant Physiol 2018 Dec 13. Epub 2018 Dec 13.

RIKEN CITY: Saitama POSTAL_CODE: 351-0198 Japan [JP].

Spatiotemporal coordination of protein trafficking between organelles is essential for eukaryotic cells, and the post-Golgi interface, including the trans-Golgi network (TGN), is a pivotal hub for multiple trafficking pathways. The Golgi-released independent TGN (GI-TGN) is a compartment described only in plant cells, and its cellular and physiological roles remain elusive. In Arabidopsis thaliana, the SYP4 group Qa-SNARE (soluble N-ethyl-maleimide sensitive factor attachment protein receptor) membrane fusion proteins are shared components of TGN and GI-TGN and regulate secretory and vacuolar transport. Read More

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December 2018

Deadbeat-fuzzy controller for the power control of a Doubly Fed Induction Generator based wind power system.

ISA Trans 2018 Dec 5. Epub 2018 Dec 5.

Federal University of ABC - Santo André, SP, Brazil. Electronic address:

This paper proposes a Fuzzy Logic Controller for improvement of the steady-state response of a Doubly Fed Induction Generator used in a wind energy system, and governed by means of a Deadbeat Power Controller. The generator mathematical model is consistent with the Stator Flux oriented strategy in the synchronous reference frame. Different simulation scenarios were developed in Matlab/Simulink to evaluate the dynamic and the steady-state responses. Read More

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December 2018

New results on stability of switched continuous-time systems with all subsystems unstable.

ISA Trans 2018 Dec 5. Epub 2018 Dec 5.

School of Information and Communication Engineering, University of Electronic Science and Technology of China, Chengdu 611731, Sichuan, China. Electronic address:

This paper studies the stability problem of switched continuous-time systems with all subsystems unstable. Switchings can be classified into two categories depending on their dwell time, which are the switching without divergence time and the switching with divergence time. Based on this, stability conditions under the bounded maximum average dwell time (BMADT) switching are established. Read More

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December 2018
1 Read

A new rooted tree optimization algorithm for indirect power control of wind turbine based on a doubly-fed induction generator.

ISA Trans 2018 Nov 26. Epub 2018 Nov 26.

University of Brest, FRE CNRS 3744 IRDL, CS 93837, 29238 Brest, France; Shanghai Maritime University, 201306 Shanghai, China.

A new control strategy based on the root tree optimization (RTO) is presented in order to reduce the chattering phenomena in active and reactive powers, and to minimize the harmonic currents which appear mostly at the level of the rotor side converter (RSC), in a doubly-fed induction generator (DFIG). The root tree optimization is used to adjust the parameters (K,K) of PI controller (RTO-PI). Simulation results are presented to demonstrate the effectiveness of the new proposed technique. Read More

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November 2018

Adaptive sliding mode current control with sliding mode disturbance observer for PMSM drives.

ISA Trans 2018 Nov 30. Epub 2018 Nov 30.

Changchun Institute of Optics, Fine Mechanic and Physics, Chinese Academy of Science, Changchun, Jilin 130033, China.

This paper focuses on the current control of a permanent magnet synchronous motor (PMSM) for electric drives with model uncertainties and external disturbances. To improve the performance of the PMSM current loop in terms of the speed of response, tracking accuracy, and robustness, a hybrid control strategy is proposed by combining the adaptive sliding mode control and sliding mode disturbance observer (SMDO). An adaptive law is introduced in the sliding mode current controller to improve the dynamic response speed of the current loop and robustness of the PMSM drive system to the existing parameter variations. Read More

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November 2018

Ventral and dorsal visual pathways exhibit abnormalities of static and dynamic connectivities, respectively, in patients with schizophrenia.

Schizophr Res 2018 Dec 10. Epub 2018 Dec 10.

Medical Imaging Department, Nanfang Hospital, Southern Medical University, Guangzhou, China. Electronic address:

Previous studies suggest that schizophrenia-related visual perceptual abnormalities are primarily attributed to deficits of the dorsal rather than ventral visual pathway. In this study, we comparatively explored changes in dorsal and ventral networks in schizophrenia patients in both static and dynamic functional connectivity (FC). Resting-state MR scans were acquired for forty schizophrenia patients and twenty-four healthy controls matched for age and gender. Read More

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December 2018
1 Read

Lung Scintigraphy in the Assessment of Aerosol Deposition and Clearance.

Semin Nucl Med 2019 Jan 22;49(1):47-57. Epub 2018 Nov 22.

Department of Medical Radiation Physics and Nuclear Medicine, Karolinska University Hospital, Stockholm, Sweden; Department of Oncology-pathology. Karolinska Institutet, Stockholm, Sweden. Electronic address:

Environmental and occupational exposure to particulate aerosols is known to have negative health effects. However little is known about how these aerosols trigger the development of pathophysiological mechanisms in the body or the fate of ultrafine particles in the lungs after inhalation. The development of aerosols of different origin that can be labeled to a large variety with radionuclides compatible with clinical gamma camera systems opens the possibility of using lung scintigraphy imaging to study these causalities in detail. Read More

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January 2019

The bacterial community significantly promotes cast iron corrosion in reclaimed wastewater distribution systems.

Microbiome 2018 Dec 13;6(1):222. Epub 2018 Dec 13.

Guangdong Provincial Engineering Research Center for Urban Water Recycling and Environmental Safety, Graduate School at Shenzhen, Tsinghua University, Shenzhen, China.

Background: Currently, the effect of the bacterial community on cast iron corrosion process does not reach consensus. Moreover, some studies have produced contrasting results, suggesting that bacteria can either accelerate or inhibit corrosion.

Results: The long-term effects of the bacterial community on cast iron corrosion in reclaimed wastewater distribution systems were investigated from both spatial (yellow layer vs. Read More

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December 2018

Assessment of the modulation degrees of intensity-modulated radiation therapy plans.

Radiat Oncol 2018 Dec 13;13(1):244. Epub 2018 Dec 13.

Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea.

Background: To evaluate the modulation indices (MIs) for predicting the plan delivery accuracies of intensity-modulated radiation therapy (IMRT) plans.

Methods: A total of 100 dynamic IMRT plans that used TrueBeam STx and 102 dynamic IMRT plans that used Trilogy were selected. For each plan, various MIs were calculated, which included the modulation complexity score (MCS), plan-averaged beam area (PA), plan-averaged beam irregularity (PI), plan-averaged beam modulation (PM), MI quantifying multi-leaf collimator (MLC) speeds (MI), MI quantifying MLC acceleration (MI), and MI quantifying MLC acceleration and segment aperture irregularity (MI). Read More

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December 2018

Thymoma with an isolated splenic metastasis eight years after extended thymectomy: a case report.

BMC Cancer 2018 Dec 13;18(1):1249. Epub 2018 Dec 13.

Department of Surgery, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan.

Background: Thymomas are typically slow-growing tumors and AB type thymomas are considered no/low risk tumors with a better prognosis. Extra-thoracic metastases are extremely rare. To the best of our knowledge, no patient with an isolated splenic metastasis from a thymoma has been reported. Read More

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December 2018
1 Read

Global Methylome and gene expression analysis during early Peanut pod development.

BMC Plant Biol 2018 Dec 13;18(1):352. Epub 2018 Dec 13.

Biotechnology Research Center, Shandong Academy of Agricultural Sciences; Shandong Provincial Key Laboratory of Crop Genetic Improvement, Ecology and Physiology, Jinan, 250100, People's Republic of China.

Background: Early peanut pod development is an important process of peanut reproductive development. Modes of DNA methylation during early peanut pod development are still unclear, possibly because its allotetraploid genome may cause difficulty for the methylome analysis.

Results: To investigate the functions of the dynamic DNA methylation during the early development of the peanut pod, global methylome and gene expression analyses were carried out by Illumina high throughput sequencing. Read More

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December 2018
1 Read

Interstitial Fluid in Gynecologic Tumors and Its Possible Application in the Clinical Practice.

Int J Mol Sci 2018 Dec 12;19(12). Epub 2018 Dec 12.

Institute for Maternal and Child Health-IRCCS "Burlo Garofolo", 34137 Trieste, Italy.

Gynecologic cancers are an important cause of worldwide mortality. The interstitium consists of solid and fluid phases, situated between the blood vessels and cells. The interstitial fluid (IF), or fluid phase, is an extracellular fluid bathing and surrounding the tissue cells. Read More

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December 2018

Synonymous Codon Usages as an Evolutionary Dynamic for .

Int J Mol Sci 2018 Dec 12;19(12). Epub 2018 Dec 12.

State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China.

The family of contains a group of obligate intracellular bacteria that can infect a wide range of hosts. The evolutionary trend of members in this family is a hot topic, which benefits our understanding of the cross-infection of these pathogens. In this study, 14 whole genomes of 12 species were used to investigate the nucleotide, codon, and amino acid usage bias by synonymous codon usage value and information entropy method. Read More

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December 2018
1 Read

Characterization of Tunable Micro-Lenses with a Versatile Optical Measuring System.

Sensors (Basel) 2018 Dec 12;18(12). Epub 2018 Dec 12.

STMicroelectronics, 20010 Cornaredo (Mi), Italy.

In this work, we present the results of the opto⁻electro⁻mechanical characterization of tunable micro-lenses, Tlens, performed with a single-spot optical measuring system. Tested devices are composed of a transparent soft polymer layer that is deposited on a supporting glass substrate and is covered by a glass membrane with a thin-film piezoelectric actuator on top. Near-infrared optical low-coherence reflectometry is exploited for both static and low-frequency dynamic analyses in the time domain. Read More

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December 2018

MRI Study of the Influence of Surface Coating Aging on the In Vivo Biodistribution of Iron Oxide Nanoparticles.

Biosensors (Basel) 2018 Dec 12;8(4). Epub 2018 Dec 12.

Magnetic Resonance Imaging Laboratory, CIC biomaGUNE, 20014 Donostia-San Sebastián, Spain.

Medical imaging is an active field of research that fosters the necessity for novel multimodal imaging probes. In this line, nanoparticle-based contrast agents are of special interest, since those can host functional entities either within their interior, reducing potential toxic effects of the imaging tracers, or on their surface, providing high payloads of probes, due to their large surface-to-volume ratio. The long-term stability of the particles in solution is an aspect usually under-tackled during probe design in research laboratories, since their performance is generally tested briefly after synthesis. Read More

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December 2018

Application of Real-Time Cell Electronic Analysis System in Modern Pharmaceutical Evaluation and Analysis.

Molecules 2018 Dec 11;23(12). Epub 2018 Dec 11.

Beijing Body Revival Medical Technology Co., Ltd., Beijing 100088, China.

We summarized the progress of the xCELLigence real-time cell analysis (RTCA) technology application in recent years for the sake of enriching and developing the application of RTCA in the field of Chinese medicine. The RTCA system is an established electronic cellular biosensor. This system uses micro-electronic biosensor technology that is confirmed for real-time, label-free, dynamic and non-offensive monitoring of cell viability, migration, growth, spreading, and proliferation. Read More

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December 2018

Endothelial Contributions to Zebrafish Heart Regeneration.

J Cardiovasc Dev Dis 2018 Dec 11;5(4). Epub 2018 Dec 11.

Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.

Studies over the past two decades have shown heart regeneration in zebrafish to be a dynamic process, choreographed by multiple cell types. In particular, recent work has identified revascularization of the wound to be a sentinel event during heart regeneration. The cardiac endothelium has emerged as a key orchestrator of heart regeneration, influencing cardiomyocyte hyperplasia and tissue morphogenesis. Read More

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December 2018

Background Light Rejection in SPAD-Based LiDAR Sensors by Adaptive Photon Coincidence Detection.

Sensors (Basel) 2018 Dec 8;18(12). Epub 2018 Dec 8.

Department of Electronic Components and Circuits, University Duisburg-Essen, 47057 Duisburg, Germany.

Light detection and ranging (LiDAR) systems based on silicon single-photon avalanche diodes (SPAD) offer several advantages, like the fabrication of system-on-chips with a co-integrated detector and dedicated electronics, as well as low cost and high durability due to well-established CMOS technology. On the other hand, silicon-based detectors suffer from high background light in outdoor applications, like advanced driver assistance systems or autonomous driving, due to the limited wavelength range in the infrared spectrum. In this paper we present a novel method based on the adaptive adjustment of photon coincidence detection to suppress the background light and simultaneously improve the dynamic range. Read More

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December 2018

A Guided Vehicle under Fire Conditions Based on a Modified Ultrasonic Obstacle Avoidance Technology.

Sensors (Basel) 2018 Dec 10;18(12). Epub 2018 Dec 10.

Civil and Infrastructure Engineering Discipline, School of Engineering, RMIT University, Melbourne, VIC 3000, Australia.

Low visibility and hot smoke environment under fire conditions can largely hamper the related fire rescue processes. Ultrasound obstacle avoidance technology is then useful for guidance. However, the biggest challenge of adopting ultrasound technology comes from accurate distance measurements under the disturbances of high temperature and soot particle concentration. Read More

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December 2018

Explosion Suppression Mechanism Characteristics of MEMS S&A Device With In Situ Synthetic Primer.

Micromachines (Basel) 2018 Dec 10;9(12). Epub 2018 Dec 10.

National Key Laboratory of Electro-Mechanics Engineering and Control, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing 100081, China.

The traditional silicon-based micro-electro-mechanical systems (MEMS) safety and arming (S&A) device fuze cannot isolate abnormal outputs in the detonation environment, which creates hazards for personnel. To address this problem, we report the design of a MEMS S&A device with integrated silver, copper, nickel and polyimide (PI) films, which is based on the principle of a MEMS S&A device and uses copper azide as the primer. The MEMS S&A device was optimized using theoretical calculations of the explosion suppression mechanism performance in a detonation field, where the theoretical model was verified by dynamic simulation (LS-Dyna). Read More

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December 2018

Clustering Transmission Opportunity Length (CTOL) Model over Cognitive Radio Network.

Sensors (Basel) 2018 Dec 10;18(12). Epub 2018 Dec 10.

Faculty of Engineering Electrical and Computer Engineering, Shinshu University, 4-17-1, Wakasato, Nagano City 380 8553, Japan.

This paper investigated the throughput performance of a secondary user (SU) for a random primary user (PU) activity in a realistic experimental model. This paper proposed a sensing and frame duration of the SU to maximize the SU throughput under the collision probability constraint. The throughput of the SU and the probability of collisions depend on the pattern of PU activities. Read More

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December 2018

Fatty Acid Composition and Thermotropic Behavior of Glycolipids and Other Membrane Lipids of Ulva lactuca (Chlorophyta) Inhabiting Different Climatic Zones.

Mar Drugs 2018 Dec 7;16(12). Epub 2018 Dec 7.

Department of Biochemistry, Microbiology and Biotechnology, School of Natural Sciences, Far Eastern Federal University, Vladivostok 690091, Russia.

Increasing global temperatures are expected to increase the risk of extinction of various species due to acceleration in the pace of shifting climate zones. Nevertheless, there is no information on the physicochemical properties of membrane lipids that enable the adaptation of the algae to different climatic zones. The present work aimed to compare fatty acid composition and thermal transitions of membrane lipids from green macroalgae harvested in the Sea of Japan and the Adriatic Sea in summer. Read More

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December 2018

Reinforcement Learning-Based Satellite Attitude Stabilization Method for Non-Cooperative Target Capturing.

Sensors (Basel) 2018 Dec 7;18(12). Epub 2018 Dec 7.

Centre for Computational Intelligence, De Montfort University, Gateway House, Leicester LE1 9BH, UK.

When a satellite performs complex tasks such as discarding a payload or capturing a non-cooperative target, it will encounter sudden changes in the attitude and mass parameters, causing unstable flying and rolling of the satellite. In such circumstances, the change of the movement and mass characteristics are unpredictable. Thus, the traditional attitude control methods are unable to stabilize the satellite since they are dependent on the mass parameters of the controlled object. Read More

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December 2018

Viscoelastic Mechanical Responses of HMAP under Moving Load.

Materials (Basel) 2018 Dec 7;11(12). Epub 2018 Dec 7.

Institute of Transportation Engineering, Zhejiang University, Hangzhou 3100580, China.

In order to represent the mechanical response laws of high-modulus asphalt pavement (HMAP) faithfully and objectively, the viscoelasticity of high-modulus asphalt mixture (HMAM) was considered, and the viscoelastic mechanical responses were calculated systematically based on moving load by numerical simulations. The performances of the HMAP in resistance to the deformation and the cracking at the bottom layer were compared with the ordinary asphalt pavement. Firstly, Lubao and Honeywell 7686 (H7686) were selected as the high modulus modifiers. Read More

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December 2018

Different Pathogen Defense Strategies in : More than Pathogen Recognition.

Cells 2018 Dec 7;7(12). Epub 2018 Dec 7.

Key Laboratory of Bio-Resources and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, China.

Plants constantly suffer from simultaneous infection by multiple pathogens, which can be divided into biotrophic, hemibiotrophic, and necrotrophic pathogens, according to their lifestyles. Many studies have contributed to improving our knowledge of how plants can defend against pathogens, involving different layers of defense mechanisms. In this sense, the review discusses: (1) the functions of PAMP (pathogen-associated molecular pattern)-triggered immunity (PTI) and effector-triggered immunity (ETI), (2) evidence highlighting the functions of salicylic acid (SA) and jasmonic acid (JA)/ethylene (ET)-mediated signaling pathways downstream of PTI and ETI, and (3) other defense aspects, including many novel small molecules that are involved in defense and phenomena, including systemic acquired resistance (SAR) and priming. Read More

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December 2018

Validation of a Dynamic Planning Navigation Strategy Applied to Mobile Terrestrial Robots.

Sensors (Basel) 2018 Dec 7;18(12). Epub 2018 Dec 7.

Department of Computer Engineering and Automation, Center of Technology, Federal University of Rio Grande do Norte-UFRN, 59078-970, Brazil.

This work describes the performance of a DPNA-GA (Dynamic Planning Navigation Algorithm optimized with Genetic Algorithm) algorithm applied to autonomous navigation in unknown static and dynamic terrestrial environments. The main aim was to validate the functionality and robustness of the DPNA-GA, with variations of genetic parameters including the crossover rate and population size. To this end, simulations were performed of static and dynamic environments, applying the different conditions. Read More

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December 2018

Advances in the Structural Health Monitoring of Bridges Using Piezoelectric Transducers.

Sensors (Basel) 2018 Dec 7;18(12). Epub 2018 Dec 7.

School of Traffic Engineering, Shenyang Jianzhu University, Shenyang 110168, Liaoning, China.

With the rapid development of the world's transportation infrastructure, many long-span bridges were constructed in recent years, especially in China. However, these bridges are easily subjected to various damages due to dynamic loads (such as wind-, earthquake-, and vehicle-induced vibration) or environmental factors (such as corrosion). Therefore, structural health monitoring (SHM) is vital to guarantee the safety of bridges in their service lives. Read More

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December 2018

Ictal networks of temporal lobe epilepsy: views from high-frequency oscillations in stereoelectroencephalography.

Authors:

J Neurosurg 2018 Nov 1:1-9. Epub 2018 Nov 1.

OBJECTIVEIn this study, the authors investigated high-frequency oscillation (HFO) networks during seizures in order to determine how HFOs spread from the focal cerebral cortex and become synchronized across various areas of the brain.METHODSAll data were obtained from stereoelectroencephalography (SEEG) signals in patients with drug-resistant temporal lobe epilepsy (TLE). The authors calculated intercontact cross-coefficients between all pairs of contacts to construct HFO networks in 20 seizures that occurred in 5 patients. Read More

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November 2018