Ann Plast Surg 2021 Feb 12. Epub 2021 Feb 12.
From the Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA Research Department, Shriners Hospitals for Children, Cincinnati, OH Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH.
Abstract: Dupuytren disease is a connective tissue disorder occurring on the palm, causing flexion contractures of fingers. There is a pressing need for therapeutic interventions that can slow, stop, or even incrementally reverse the progression of the disease. Numerous in vitro studies have shed light on cellular and molecular agents that contribute to contractures. Read More