Search Our Scientific Publications & Authors

Indian J Gastroenterol 2021 May 11. Epub 2021 May 11.

Department of Gastroenterology, G B Pant Institute of Postgraduate Medical Education and Research, 1, J L N Marg, New Delhi, 110 002, India.

Background: Scope-induced duodenal perforation is a life-threatening complication and surgery remains the standard of care. With the advent of over-the-scope clip (OTSC), scope-induced perforations are increasingly managed conservatively, though there is no study comparing this form of non-surgical treatment with surgery. We aimed to compare OTSC and surgery in the management of scope-induced perforation of the duodenum. Read More

Cureus 2021 Apr 7;13(4):e14353. Epub 2021 Apr 7.

Gastroenterology, Shimane University Hospital, Izumo, JPN.

Background This study was performed to examine the prevalence of asymptomatic angiodysplasia detected in upper gastrointestinal endoscopic examinations and of hereditary hemorrhagic telangiectasia (HHT) suspected cases. Methodology The study participants were 5,034 individuals (3,206 males, 1,828 females; mean age 53.5 ± 9. Read More

BMJ Case Rep 2021 May 10;14(5). Epub 2021 May 10.

Department of Surgery, Greenslopes Private Hospital, Brisbane, Queensland, Australia

A 59-year-old woman was referred to a specialist gastroenterologist following a year of intermittent abdominal bloating and worsening reflux. In the month prior to referral, the patient developed intermittent large volume vomiting consisting of bile-stained undigested food. This was accompanied by a 10 kg weight loss. Read More

Ann Surg Oncol 2021 May 9. Epub 2021 May 9.

Department of Surgery, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea.

Background: Limited evidence exists for the safety and oncologic efficacy of minimally invasive surgery (MIS) for nonfunctioning pancreatic neuroendocrine tumors (NF-PNETs) according to tumor location. This study aimed to compare the surgical outcomes of MIS and open surgery (OS) for right- or left-sided NF-PNETs.

Methods: The study collected data on patients who underwent surgical resection (pancreatoduodenectomy, distal/total/central pancreatectomy, duodenum-preserving pancreas head resection, or enucleation) of a localized NF-PNET between January 2000 and July 2017 at 14 institutions. Read More

Cureus 2021 Apr 6;13(4):e14323. Epub 2021 Apr 6.

Internal Medicine, University of California, Riverside School of Medicine, Riverside, USA.

Periampullary carcinoma is a broad term used to define the group of carcinomas arising from the head of the pancreas, the distal common bile duct, and the duodenum. It is clinically important to differentiate ampullary from periampullary carcinoma as this can affect resectability and prognosis. Atypical left-sided chest pain is an atypical presentation of periampullary duodenal adenocarcinoma. Read More

Gastroenterol Hepatol Bed Bench 2021 ;14(2):185-189

Division of Gastroenterology, Department of Internal Medicine, Hatyai Hospital, Songkhla, Thailand.

Follicular lymphoma (FL) is one of the most common types of non-Hodgkin lymphoma (NHL). The gastrointestinal tract is the most involved extra-nodal site of NHL. Primary duodenal FL (DFL) is a rare entity with only a few reported cases. Read More

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2021 Apr;43(2):222-229

Department of Gastroenterology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.

Objective To analyze clinical characteristics and short-term efficacy of endoscopic hemostasis in acute duodenal hemorrhage. Methods A retrospective study was conducted for the patients who received endoscopy in the PUMC Hospital due to upper gastrointestinal bleeding and were confirmed to be on account of duodenal lesions for bleeding from January 2011 to December 2018.Clinical information of patients was collected,including demographics,comorbidities,and medication use. Read More

Georgian Med News 2021 Mar(312):105-113

I. Horbachevsky Ternopil National Medical University, Ukraine.

Aim of the research - comprehensive morphometric assessment of the structural and spatial organization of the circulatory system of the duodenum in obstructive cholestasis in intact animals. Three days after the simulated obstructive cholestasis in 3 experimental animals, on examination of radiographs there is a tendency to reorient the arterial and venous bed of the duodenum. Analysis of morphometric parameters also showed a tendency to constriction of arteries and varicose veins. Read More

BMJ Case Rep 2021 May 7;14(5). Epub 2021 May 7.

Department of Medical Oncology, HealthCare Global Enterprises Ltd, Bangalore, Karnataka, India.

Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. Dedifferentiation in these tumours occurs rarely, and when it does occurs most commonly after prolonged treatment with imatinib. We report the case of a 64-year-old man who presented with a mass of 8×7×3 cm dimensions involving the duodenum and head of the pancreas. Read More

Morphologie 2021 May 4. Epub 2021 May 4.

Division of Anatomy, Department 1, Faculty of Dental Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania. Electronic address:

The celiaco-mesenteric anastomoses occur either directly between the celiac trunk and the superior mesenteric artery (SMA), or between different branches of them. A rarely occurring such anastomosis is the arc of Bühler. A new variant of arc of Bühler was found incidentally during a retrospective study of the computed tomography angiograms of a 62 y. Read More

Int J Surg Case Rep 2021 Apr 29;82:105927. Epub 2021 Apr 29.

Department of General Surgery, Mata Chanan Devi Hospital, New Delhi, India.

Introduction: Horseshoe kidneys are the most common fusion defect of the kidneys, which amounts to about 0.25% of the population. They are usually asymptomatic and are often identified incidentally. Read More

BMJ Case Rep 2021 May 6;14(5). Epub 2021 May 6.

Department of Hepato Pancreato Biliary(HPB) Surgery and Liver Transplant, HealthCare Global Enterprises Ltd, Bangalore, Karnataka, India.

Inflammatory myofibroblastic tumours (IMTs) are rare benign neoplasms of intermediate malignant potential that are found in the lungs and rarely at extrapulmonary sites common in children and young adults. IMTs tend to be locally invasive and have some amount of metastatic potential as well. We present two cases of IMTs involving the duodenum, pancreas and distal bile duct. Read More

BMJ Case Rep 2021 May 6;14(5). Epub 2021 May 6.

Department of Diabetes and Endocrinology, Mater Dei Hospital, Msida, Malta.

An elderly gentleman was admitted to hospital with severe hypokalaemia of 1.75mmol/L. A background of a recently diagnosed metastatic gastric carcinoma with a neuroendocrine component pointed towards the diagnosis of ectopic ACTH secretion causing this dangerous electrolyte imbalance. Read More

Top Companion Anim Med 2021 May 3:100537. Epub 2021 May 3.

University of Murcia: Universidad de Murcia, Espinardo, Murcia, Spain.

Endoscopic polypectomy is commonly performed in human medicine, with large-scale studies reported. However, few reports have described its use in veterinary medicine and, specifically, the procedure in the case of duodenal polyps in cats has not been reported. A 7 kg 14-year-old cat presented with recurrent vomiting for several months. Read More

Biol Trace Elem Res 2021 May 5. Epub 2021 May 5.

Centre for Nutrition and Food Sciences, Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, Brisbane, QLD, 4072, Australia.

This experiment was conducted to investigate the effect of the supplementation of hot-melt extrusion (HME) processed zinc sulfate (ZnSO) on the growth performance, antioxidative activity, pancreatic digestive enzyme, small intestinal morphology, nutrient digestibility, and Zn content in broilers. The chicks were allocated to three treatments, each of which had five replicates of 15 chicks per replicate. The broiler chickens were assigned to three dietary treatments: the control (without supplemental Zn), IN-Zn (ZnSO, 80 mg/kg), and HME-Zn (HME processed ZnSO as nano-Zn, 80 mg/kg). Read More

Intern Med 2021 1;60(9):1433-1442. Epub 2021 May 1.

Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Japan.

The gastrointestinal tract is considered an important endocrine organ for controlling glucose homeostasis via the production of incretins. A 21-year-old man emergently underwent total colectomy due to severe ulcerative colitis, and overt diabetes became evident. Weekly administration of a glucagon-like peptide (GLP)-1 receptor agonist (RA) dramatically improved his glucose control. Read More

N Engl J Med 2021 05;384(18):1778

Washington University School of Medicine, St. Louis, MO

N Engl J Med 2021 05;384(18):1777-1778

Centre Hospitalier Universitaire de Lille, Lille, France

N Engl J Med 2021 05;384(18):1777

National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD

J Gastrointestin Liver Dis 2021 May 3. Epub 2021 May 3.

Academic Department of Gastroenterology, Royal Hallamshire Hospital, Sheffield Teaching Hospitals, Sheffield, United Kingdom.

Background And Aims: Methods of assessing gluten-free diet (GFD) adherence in adults with coeliac disease (CD) include serological testing, dietitian evaluation, questionnaires and repeat duodenal biopsies. Persisting villous atrophy (VA) is associated with CD complications, however gastroscopy with biopsies is expensive and invasive. This study aimed to assess the abilities of a duodenal bulb (D1) biopsy and the Celiac Dietary Adherence Test (CDAT) to detect persisting VA in adults with CD. Read More

Clin J Gastroenterol 2021 May 5. Epub 2021 May 5.

Department of Gastroenterology, National Hospital Organization Kyoto Medical Center, 1-1 Mukaihatacho, Fukakusa, Kyoto, 612-8555, Japan.

Immunoglobulin A (IgA) vasculitis mainly affects the joints, skin, kidneys, and gastrointestinal tract; however, purpura is an essential diagnostic criterion. Here, we report an unusual case of IgA vasculitis without purpura in an elderly woman. A 76-year-old woman was admitted to our hospital complaining of diarrhea and abdominal pain. Read More

J Anal Toxicol 2021 May 5. Epub 2021 May 5.

Institute of Legal Medicine, Saarland University, 66421 Homburg, Germany.

In spite of a decreasing number of new releases, New Synthetic Opioids (NSO) are gaining increasing importance in postmortem (PM) forensic toxicology. For the interpretation of analytical results, toxicokinetic (TK) data, e.g. Read More

bioRxiv 2021 Apr 28. Epub 2021 Apr 28.

Diarrhea occurs in 2-50% of cases of COVID-19 (∼8% is average across series). The diarrhea does not appear to account for the disease mortality and its contribution to the morbidity has not been defined, even though it is a component of Long Covid or post-infectious aspects of the disease. Even less is known about the pathophysiologic mechanism of the diarrhea. Read More

Radiat Oncol 2021 May 4;16(1):84. Epub 2021 May 4.

Department of Radiation Oncology, University Hospital of Zurich, University of Zurich, Raemistrasse 100, 8091, Zurich, Germany.

Purpose: To assess the effects of daily adaptive MR-guided replanning in stereotactic body radiation therapy (SBRT) of liver metastases based on a patient individual longitudinal dosimetric analysis.

Methods: Fifteen patients assigned to SBRT for oligometastatic liver metastases underwent daily MR-guided target localization and on-table treatment plan re-optimization. Gross tumor volume (GTV) and organs at risk (OARs) were adapted to the anatomy-of-the-day. Read More

Cancers (Basel) 2021 Apr 29;13(9). Epub 2021 Apr 29.

Department of Radiation Oncology, Division of Radiation Oncology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.

We developed and implemented an objective toxicity scoring system to be used during endoscopic evaluation of the upper gastrointestinal (GI) tract in order to directly assess changes in toxicity during the radiation treatment of pancreatic cancer. We assessed and validated the upper GI toxicity of 19 locally advanced pancreatic cancer trial patients undergoing stereotactic body radiation therapy (SBRT). Wilcoxon-signed rank tests were used to compare pre- and post-SBRT scores. Read More

Animals (Basel) 2021 Apr 30;11(5). Epub 2021 Apr 30.

State Key Laboratory of Animal Nutrition, Institute of Animal Sciences of Chinese Academy of Agricultural Sciences, No. 2 Yuan Ming Yuan West Road, Beijing 100193, China.

The study was conducted to investigate the effects of replacing antibiotic growth promoters (AGPs) with an egg immunoglobulin (IgY) combined with phytomolecules (PM) on the growth rate, serum immunity, and intestinal health of weaned pigs challenged with K88 ( K88). A total of 192 piglets were weaned at 28 days old with an average weight of 7.29 (± 0. Read More

Arthritis Res Ther 2021 May 3;23(1):133. Epub 2021 May 3.

Department of Rheumatology and Clinical Immunology, Kobe University Graduate School of Medicine, Kobe, Japan.

Background: Systemic sclerosis (SSc) is a chronic autoimmune-mediated connective tissue disorder. Although the etiology of the disease remains undetermined, SSc is characterized by fibrosis and proliferative vascular lesions of the skin and internal organs. SSc involves the gastrointestinal tract in more than 90 % of patients. Read More

Endosc Int Open 2021 May 22;9(5):E735-E740. Epub 2021 Apr 22.

Department of Clinical Research, Surat Institute of Digestive Sciences (SIDS), Surat, India.

 Crush cytology is a simple and rapid method used for diagnosis of central nervous system lesions. We have evaluated the diagnostic accuracy of crush cytology for gastrointestinal tract lesions.  This was a prospective, cross-sectional, single center study, conducted on the patients who had suspected malignant lesions between August 2018 and March 2020. Read More

J Surg Case Rep 2021 Apr 22;2021(4):rjab093. Epub 2021 Apr 22.

College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.

Amyloidosis is a disorder characterized by deposition of abnormally folded proteins in the extracellular space of various tissues and organs, possibly leading to their dysfunction. In the majority of cases, amyloidosis presents with systemic involvement including the gastrointestinal tract; however, localized gastroduodenal amyloidosis is rare. We report a case of gastroduodenal amyloidosis in a 36-year-old male with multiple comorbidities who presented with right upper quadrant abdominal pain. Read More

J Cytol 2021 Jan-Mar;38(1):8-13. Epub 2021 Jan 8.

Department of Pathology, Dong-A University College of Medicine, Busan, Korea.

Context: Subtyping of solitary pulmonary lesion (SPL) in small amount of cytology specimen using a limited panel of immunohistochemistry (IHC) markers is very important to the correct choice of treatment. This study was performed to categorize non-small cell carcinoma-not otherwise specified (NSCC-NOS) on cytology in patients with SPL, especially with regard to the incidence of metastatic cancer.

Materials And Methods: We reviewed 91 cases, in which a precise morphology-based, lineage-specific IHC-aided subtyping was not possible, that qualified as NSCC-NOS on cytology. Read More