34,159 results match your criteria Duodenal Ulcers


Obesity, peptic ulcer disease and metabolic status in the Wuwei Cohort of northwest China: A cross-sectional study.

Asia Pac J Clin Nutr 2022 ;31(2):294-304

The First School of Clinical Medicine, Lanzhou University, Lanzhou, China. Email:

Background And Objectives: Peptic ulcer disease is a common digestive system disease. However, whether peptic ulcer disease and obesity are related is unclear. We assessed the associations of obesity and metabolic status with peptic ulcer disease. Read More

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January 2022

Case report: two cases of spontaneous intramural duodenal hematoma associated with pancreatitis.

Acta Biomed 2022 Jun 29;93(S1):e2022226. Epub 2022 Jun 29.

Department of Surgery, University Hospital Centre Zagreb, Zagreb, Croatia.

Intramural duodenal hematoma (IDH) is a rare entity and is generally associated with trauma. Spontaneous (nontraumatic) intramural duodenal hematoma is associated with bleeding disorders, anticoagulation therapy, alcoholism, pancreatitis, tumours  and duodenal ulcers. We report two cases of spontaneous intramural duodenal hematoma in middle-aged men who subsequently developed pancreatitis. Read More

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Diagnoses after newly recorded abdominal pain in primary care: observational cohort study.

Br J Gen Pract 2022 Apr 20. Epub 2022 Apr 20.

Cancer Diagnosis (DISCO), University of Exeter Medical School, Exeter.

Background: Non-acute abdominal pain in primary care is diagnostically challenging.

Aim: To quantify the 1-year cumulative incidence of 35 non-malignant diagnoses and nine cancers in adults after newly recorded abdominal pain in primary care.

Design And Setting: Observational cohort study of 125 793 Clinical Practice Research Datalink GOLD records. Read More

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Endoscopic and histopathological findings in adult dyspeptic patients, and their association with infection in Dhaka, Bangladesh.

IJID Reg 2022 Mar 24;2:30-34. Epub 2021 Nov 24.

Lecturer, Department of Microbiology, Dhaka Medical College, Shahbag 1000, Dhaka, Bangladesh.

Objectives: Conventional upper-intestinal endoscopy is usually performed to diagnose () associated diseases, using gastric mucosa from the biopsy. The objective of our study was to identify the prevalence of and its relation with endoscopic findings and histopathological features in dyspeptic adult patients.

Methods: Gastroduodenal biopsy specimens were collected from 143 adult dyspeptic outpatients who attended the Department of Gastroenterology, Bangabandhu Sheikh Mujib Medical University (BSMMU) and Dhaka Medical College Hospital (DMCH), for endoscopy. Read More

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Massive upper gastrointestinal bleeding due to a gastric ulcer in a newborn.

Proc (Bayl Univ Med Cent) 2022 5;35(4):567-568. Epub 2022 Apr 5.

Department of Neonatology, Dr Sami Ulus Maternity and Children Research and Training Hospital, University of Health Sciences of Turkey, Ankara, Turkey.

Usually, swallowing of maternal blood is the cause of bloody vomiting in healthy term newborns. Other reported causes include gastritis, esophagitis, gastric ulcer, and duodenal ulcer. We report a newborn girl born by cesarean at 37 weeks who had hematemesis on postnatal day 1 and hematochezia on day 2. Read More

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[A comparative analysis of the distribution of the high-risk population of upper gastrointestinal cancer and endoscopic screening compliance in two urban areas and two rural areas in China].

Zhonghua Zhong Liu Za Zhi 2022 Jun;44(6):531-539

Office of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

To analyze and compare the distribution of the high-risk population of upper gastrointestinal (UGI) cancer and the factors influencing the compliance rate of endoscopic screening in urban China and rural China. From 2015 to 2017, an epidemiological survey was conducted on residents aged 40-69 in two rural areas (Luoshan county of Henan province, Sheyang county of Jiangsu province) and two urban areas (Changsha city of Hunan province, Harbin city of Heilongjiang province). As a result, high-risk individuals were recommended for endoscopic screening. Read More

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Editorial: risk of gastric and duodenal ulcers among new users of low-dose aspirin.

Aliment Pharmacol Ther 2022 Jul;56(2):334-335

Department of Medicine, The University of Melbourne, Parkville, Victoria, Australia.

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Factors Associated with Colorectal Polyps in Middle-Aged and Elderly Populations.

Int J Environ Res Public Health 2022 Jun 20;19(12). Epub 2022 Jun 20.

Division of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 123, Dapi Road, Niaosong District, Kaohsiung 833, Taiwan.

Colorectal polyps are the precursor lesions of most colorectal cancers. This study aimed to evaluate associations between bone mineral density (BMD), metabolic syndrome (MetS), and gastrointestinal diseases with colorectal polyps in middle-aged and elderly populations. A retrospective cross-sectional study was performed using data from the health examination database of a tertiary medical center in southern Taiwan in 2015. Read More

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Antibiotic Resistance of in Children with Gastritis and Peptic Ulcers in Mekong Delta, Vietnam.

Healthcare (Basel) 2022 Jun 17;10(6). Epub 2022 Jun 17.

Department of Pharmacology and Clinical Pharmacy, Can Tho University of Medicine and Pharmacy, Can Tho City 900000, Vietnam.

Background: () infection causes gastritis, duodenal and gastric ulcers, and gastric cancer. eradication efficacy is low worldwide, and antibiotic resistance is the leading cause of therapy failure; therefore, this study was performed to determine the characteristics of antibiotic resistance of in children with gastritis, duodenal and gastric ulcer.

Methods: A cross-sectional study was conducted on 237 pediatric patients diagnosed with gastroduodenal inflammation and ulcer at two hospitals in Vietnam from March 2019 to April 2022. Read More

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Treatment of Pediatric Infection.

Antibiotics (Basel) 2022 Jun 1;11(6). Epub 2022 Jun 1.

Division of Gastroenterology, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan City 33305, Taiwan.

infection can cause gastritis, gastric or duodenal ulcers, mucosa-associated lymphoid tissue lymphoma, gastric cancer, and extra-gastrointestinal manifestations. Ideal treatment should be guided by antibiotic susceptibility testing. However, this is not feasible in many regions, so the treatment generally relies on clinical experience and regional culture sensitivity profiles. Read More

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Network Pharmacology Analysis and Experimental Verification Strategies Reveal the Action Mechanism of Danshen Decoction in Treating Ischemic Cardiomyopathy.

Evid Based Complement Alternat Med 2022 2;2022:7578055. Epub 2022 May 2.

State Key Laboratory of Quality Research in Chinese Medicine, Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, Macau, China.

Background: Danshen Decoction comprises , , and . It can promote blood circulation and remove blood stasis, and is commonly used in the treatment of gastric and duodenal ulcers, coronary heart disease, angina pectoris, etc. This research is based on network pharmacology and is experimentally verified to explore the potential mechanism of Danshen Decoction in the treatment of ischemic cardiomyopathy (ICM). Read More

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Endoscopic management of intramural spontaneous duodenal hematoma: A case report.

World J Gastroenterol 2022 May;28(20):2243-2247

Gastroenterology and Endoscopy Unit, Ospedale G. Mazzini, Teramo 64100, Italy.

Background: Intramural duodenal hematoma is a rare condition described for the first time in 1838. This condition is usually associated with blunt abdominal trauma in children. Other non-traumatic risk factors for spontaneous duodenal haematoma include several pancreatic diseases, coagulation disorders, malignancy, collagenosis, peptic ulcers, vasculitis and upper endoscopy procedures. Read More

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A Cohort Study to Compare Effects between Ulcer- and Nonulcer-Related Nonvariceal Upper Gastrointestinal Bleeding.

Appl Bionics Biomech 2022 10;2022:3342919. Epub 2022 Jun 10.

Department of Gastroenterology, Yantai Mountain Hospital, Yantai, China.

Objective: The aim of this study was to better understand the characteristics and etiology of acute nonvariceal upper gastrointestinal bleeding (ANVUGIB) in recent years in this region and to provide evidence-based medical evidence.

Methods: 100 patients with acute nonvariceal upper gastrointestinal bleeding (ANVUGIB) who met the clinical diagnostic criteria of ANVUGIB admitted to Suzhou First People's Hospital from January 2017 to December 2021 were analyzed, as well as the age difference and change rule. According to age, 100 patients were divided into young (18-39 years), middle-aged (40-59 years), and elderly (60 years and above), and the differences in the three groups were compared. Read More

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Duodenocaval Fistula: A Spontaneous Complication of Chemoradiation Therapy in Stage III Ovarian Cancer.

Cureus 2022 May 15;14(5):e25031. Epub 2022 May 15.

Oncology, Staten Island University Hospital, New York City, USA.

Duodenocaval fistula (DCF) is a rare entity which is sparsely described in the literature. Few etiologies have been listed including chemoradiation therapy. Early recognition may reduce the high mortality rate. Read More

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Retrospective analysis of different therapeutic approaches for retroperitoneal duodenal perforations.

Sci Rep 2022 Jun 17;12(1):10243. Epub 2022 Jun 17.

Department of General, Visceral and Transplant Surgery, University Hospital of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany.

Surgical therapy of duodenal perforation into the retroperitoneum entails high morbidity. Conservative treatment and endoscopic negative pressure therapy have been suggested as promising therapeutic alternatives. We aimed to retrospectively assess outcomes of patients treated for duodenal perforation to the retroperitoneum at our department. Read More

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Spontaneous perforated duodenal diverticulum: a case series.

Acta Gastroenterol Belg 2022 Apr-Jun;85(2):387-389

Department of gastroenterology and hepatology, AZ Nikolaas, Sint-Niklaas, Belgium and Faculty of Medicine, Ghent University, Ghent, Belgium.

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Higher viral load of Epstein-Barr virus in gastric cancer compared with non-cancerous gastroduodenal tissues.

Infez Med 2022 1;30(2):263-271. Epub 2022 Jun 1.

Cancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Introduction: Epstein-Barr Virus (EBV)-associated gastric cancer is a distinct molecular subtype of gastrointestinal carcinomas as defined by the Cancer Genome Atlas.

Methods: In the present study 237 samples from Iranian patients diagnosed with gastric cancer and gastroduodenal disease were retrospectively examined for EBV infection by quantitative Real-Time PCR.

Results: Of the 237 samples tested, EBV DNA was detected in 37 samples (15. Read More

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Gastric Helicobacter species associated with dogs, cats and pigs: significance for public and animal health.

Vet Res 2022 Jun 13;53(1):42. Epub 2022 Jun 13.

Department of Pathobiology, Pharmacology and Zoological Medicine, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.

This article focuses on the pathogenic significance of Helicobacter species naturally colonizing the stomach of dogs, cats and pigs. These gastric "non-Helicobacter (H.) pylori Helicobacter species" (NHPH) are less well-known than the human adapted H. Read More

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Analysis of Adverse Reactions of Aspirin in Prophylaxis Medication Based on FAERS Database.

Comput Math Methods Med 2022 26;2022:7882277. Epub 2022 May 26.

Department of Neurology, Jinnan Nanjiao Hospital, Jinan City 250000, Shandong Province, China.

Objective: As the most commonly used drug in the world, aspirin has shown benefits for myocardial infarction, stroke, and vascular death in many secondary prevention trials and their meta-analysis. The purpose of this study was to evaluate the association between aspirin and its adverse reactions as a preventive drug using the FDA adverse event reporting system (FAERS).

Methods: The FAERS database was queried for the adverse drug events (ADE) reported from the first quarter of 2004 to the second quarter of 2021. Read More

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The Association Between Oral Helicobacter pylori and Gastric Complications: A Comprehensive Review.

Cureus 2022 May 3;14(5):e24703. Epub 2022 May 3.

Department of Oral Biology, Faculty of Dentistry, King Abdulaziz University, Jeddah, SAU.

() is linked to chronic gastritis, duodenal or gastric ulcers, and gastric cancer (GC). Because the oral cavity is the first component of the gastrointestinal tract (GIT) and the entrance point for , it has been proposed as a possible reservoir of . As a result, a putative oral-oral transmission pathway of poses the possibility of whether personal contact, such as kissing or sharing a meal, might trigger transmission. Read More

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Upper gastrointestinal system bleedings in COVID-19 patients: Risk factors and management/a retrospective cohort study.

Ulus Travma Acil Cerrahi Derg 2022 Jun;28(6):762-768

Department of General Surgery, University of Health Sciences, Gülhane Training and Research Hospital, Ankara-Turkey.

Background: Upper gastrointestinal system bleeding (UGIB) that occurs with the effect of coagulopathy due to COVID-19 disease itself and drugs such as LMWH and steroids used in the treatment negatively affects the outcomes. In this study, we aimed to examine the frequency of gastrointestinal system bleeding in COVID-19 patients, risk factors, effect on outcomes, and management.

Methods: Institutional center (a third-level pandemic center) database was searched for patients hospitalized for COVID-19 between March 11, 2020, and December 17, 2020, retrospectively. Read More

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Iatrogenic duodenal diverticular perforation during a right laparoscopic nephroureterectomy: a rare complication.

BMJ Case Rep 2022 Jun 1;15(6). Epub 2022 Jun 1.

Department of Urology, Wagga Wagga Base Hospital, Wagga Wagga, New South Wales, Australia.

Duodenal diverticulum perforation is a rare and life-threatening pathology. Perforation secondary to iatrogenic causes is rare, with only 14 cases previously reported. This paper explores a world-first case report on iatrogenic duodenal diverticulum perforation during right laparoscopic nephroureterectomy and a systematic review of all reported cases of duodenal diverticulum perforation in the literature. Read More

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Endoscopic-catheter-directed infusion of diluted (-)-noradrenaline for atypical hemobilia caused by liver abscess: A case report.

World J Clin Cases 2022 Apr;10(10):3306-3312

Department of Liver Surgery & Liver Transplantation, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu 610044, Sichuan Province, China.

Background: Hemobilia occurs when there is a fistula between hepatic blood vessels and biliary radicles, and represents only a minority of upper gastrointestinal hemorrhages. Causes of hemobilia are varied, but liver abscess rarely causes hemobilia and only a few cases have been reported. Here, we present a case of atypical hemobilia caused by liver abscess that was successfully managed by endoscopic hepatobiliary intervention through endoscopic retrograde cholangiopancreatography (ERCP). Read More

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Protects Against Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Restoring the Intestinal Mucosal Barrier and Modulating the Oncostatin M/Oncostatin M Receptor Pathway.

Front Pharmacol 2022 13;13:819826. Epub 2022 May 13.

The College of Life Sciences, Northwest University, Xi'an, China.

(IR) is a traditional Chinese medicine used for the clinical treatment of gastric ulcers and duodenal ulcers; however, the effect of IR on ulcerative colitis (UC) and its underlying mechanism remains unclear. This study investigated the therapeutic effect of IR on UC mice induced by dextran sulfate sodium (DSS) as well as the potential underlying mechanism. The main components of IR were analyzed by ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry. Read More

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Crack cocaine abuse as an undescribed cause of gastric outlet obstruction.

Rev Esp Enferm Dig 2022 May 31. Epub 2022 May 31.

Gastroenterología y Endoscopia Digestiva, Hospital Universitario UANL, México.

A 32-year-old male with crack-cocaine abuse for 10 years, 300 g/day. He started with epigastric abdominal pain, intensity 10/10, he went to another hospital where a perforated peptic ulcer was suspected and a laparotomy was performed, with no findings. Subsequently, he started with vomiting and weight loss, on admission, a gastric outlet obstruction (GOO) was suspected and CT scan showed a concentric duodenal growth. Read More

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Endoscopic findings among geriatric patients with anaemia and chronic kidney disease at a tertiary teaching hospital in Malaysia.

Med J Malaysia 2022 05;77(3):284-291

Universiti Kebangsaan Malaysia, Faculty of Medicine, Gastroenterology Unit, Kuala Lumpur, Malaysia.

Background: Older people with chronic kidney disease (CKD) may be anaemic due to various reasons, and they are vulnerable to various consequences. One of the most important causes of anaemia to be recognised in this population is gastrointestinal loss. The outcome can be improved by early detection, careful investigation, and suitable therapies. Read More

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and the Role of Lipopolysaccharide Variation in Innate Immune Evasion.

Front Immunol 2022 13;13:868225. Epub 2022 May 13.

School of Science, RMIT University, Melbourne, VIC, Australia.

is an important human pathogen that infects half the human population and can lead to significant clinical outcomes such as acute and chronic gastritis, duodenal ulcer, and gastric adenocarcinoma. To establish infection, employs several mechanisms to overcome the innate and adaptive immune systems. can modulate interleukin (IL) secretion and innate immune cell function by the action of several virulence factors such as VacA, CagA and the type IV secretion system. Read More

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Improvement of Three Duodenal Re-leaks: Two-way Vacuum-assisted Closure.

J Coll Physicians Surg Pak 2022 Apr;32(4):S15-S17

Department of Surgery, University of Health Sciences, Okmeydani Education and Research Hospital, Istanbul, Turkey.

We share our experience of a two-way vacuum-assisted closure (VAC) technique that allows patients to heal when generalised peritonitis develops because of a recurrent duodenal leak. Two patients underwent omentoplasty for duodenal ulcer perforation and one patient underwent antrectomy, gastrojejunostomy, and tube duodenostomy. Two-way VAC was performed by taking an abdominal fluid culture and washing the abdomen with 6-12 litres of warm saline. Read More

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Diabetic Neuropathic Cachexia: A Clinical Case and Review of Literature.

Life (Basel) 2022 May 4;12(5). Epub 2022 May 4.

Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 42121 Modena, Italy.

A 46-year-old man was admitted to the surgical department because of abdominal pain and anemia, with the radiological finding of a perforated duodenal ulcer, and underwent laparoscopic surgical treatment. Type 2 diabetes mellitus (T2DM) had been diagnosed 5 years earlier and treated with diet. At clinical investigation, the patient was depressed and anorexic; moreover, he complained of lower extremity weakness and bilateral feet pain, burning in nature and accompanied by allodynia. Read More

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